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Hypertension

journal
https://www.readbyqxmd.com/read/29776989/hypertension-in-hiv-infected-adults-novel-pathophysiologic-mechanisms
#1
REVIEW
Sasha A Fahme, Gerald S Bloomfield, Robert Peck
No abstract text is available yet for this article.
May 18, 2018: Hypertension
https://www.readbyqxmd.com/read/29760154/maternal-exposure-to-ambient-particulate-matter-%C3%A2-2-5-%C3%A2%C2%B5m-during-pregnancy-and-the-risk-for-high-blood-pressure-in-childhood
#2
Mingyu Zhang, Noel T Mueller, Hongjian Wang, Xiumei Hong, Lawrence J Appel, Xiaobin Wang
Exposure to ambient air pollution has been associated with greater risk of elevated blood pressure (BP) in adults and children. Recent evidence suggests that air pollution exposure in pregnancy may also portend increased risk for the next generation; however, few studies have examined this relationship. We conducted a prospective study of 1293 mothers in the Boston Birth Cohort (enrolled 1998-2012) and their children who had follow-up visits between 3 and 9 years of age and complete exposure and outcome data...
May 14, 2018: Hypertension
https://www.readbyqxmd.com/read/29760153/do-maternal-air-pollution-exposures-have-long-lasting-influences-on-child-blood-pressure
#3
EDITORIAL
Diane R Gold, Antonella Zanobetti
No abstract text is available yet for this article.
May 14, 2018: Hypertension
https://www.readbyqxmd.com/read/29760152/20-hete-hypertension-and-beyond
#4
REVIEW
Richard J Roman, Fan Fan
No abstract text is available yet for this article.
May 14, 2018: Hypertension
https://www.readbyqxmd.com/read/29760151/salt-intake-and-immunity
#5
REVIEW
Baris Afsar, Masanari Kuwabara, Alberto Ortiz, Aslihan Yerlikaya, Dimitrie Siriopol, Adrian Covic, Bernardo Rodriguez-Iturbe, Richard J Johnson, Mehmet Kanbay
No abstract text is available yet for this article.
May 14, 2018: Hypertension
https://www.readbyqxmd.com/read/29735638/can-we-end-the-salt-wars-with-a-randomized-clinical-trial-in-a-controlled-environment
#6
EDITORIAL
Daniel W Jones, Friedrich C Luft, Paul K Whelton, Michael H Alderman, John E Hall, Eric D Peterson, Robert M Califf, David A McCarron
No abstract text is available yet for this article.
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29735637/saga-of-familial-hyperaldosteronism-yet-a-new-channel
#7
REVIEW
Livia Lenzini, Selene Prisco, Brasilina Caroccia, Gian Paolo Rossi
No abstract text is available yet for this article.
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29735636/potential-protective-mechanism-in-the-cardiac-microvascular-injury
#8
Xiuchuan Li, Juanni Hou, Jin Du, Jian Feng, Yi Yang, Yang Shen, Sha Chen, Juan Feng, Dachun Yang, De Li, Haifeng Pei, Yongjian Yang
Cardiac microvascular injury often occurs in patients with type 2 diabetes mellitus (T2DM) who develop hyperglycemia and hyperlipidemia. However, besides reported contradictory roles in cardiac diseases, the function of TRPV1 (transient receptor potential vanilloid 1) in cardiac microvessels is not well defined. This study was performed to determine the detailed role of TRPV1 in cardiac microvascular endothelial cells (CMECs) in T2DM. T2DM mice were established by multiple injections of low-dose streptozotocin and high-fat feeding...
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29735635/case-of-refractory-hypertension-controlled-after-aortic-and-mitral-valve-replacement-and-coronary-artery-bypass-grafting
#9
Mohammed Siddiqui, Robert A Phillips, Michael Bursztyn, Domenic Sica, Alejandro Velasco, Eric K Judd, Tanja Dudenbostel, Steven G Lloyd, Suzanne Oparil, David A Calhoun
No abstract text is available yet for this article.
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29735634/evaluation-of-sildenafil-and-tadalafil-for-reversing-constriction-of-fetal-arteries-in-a-human-placenta-perfusion-model
#10
Robert B Walton, Luckey C Reed, Sarah M Estrada, Stacey S Schmiedecke, Diana L Villazana-Kretzer, Peter G Napolitano, Nicholas Ieronimakis
Fetal growth restriction resulting from reduced placental blood perfusion is a major cause of neonatal morbidity and mortality. Aside from intense surveillance and early delivery, there is no treatment for fetal growth restriction. A potential treatment associated with placental vasoconstriction is the class of PDE5 (phosphodiesterase type 5) inhibitors such as sildenafil, which is known to cross the placenta. In contrast, tadalafil, a more potent and selective PDE5 inhibitor has not been studied in pregnancy or experimental models of fetal growth restriction...
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29735633/atrial-fibrillation-detection-during-24-hour-ambulatory-blood-pressure-monitoring-comparison-with-24-hour-electrocardiography
#11
Anastasios Kollias, Antonios Destounis, Petros Kalogeropoulos, Konstantinos G Kyriakoulis, Angeliki Ntineri, George S Stergiou
This study assessed the diagnostic accuracy of a novel 24-hour ambulatory blood pressure (ABP) monitor (Microlife WatchBP O3 Afib) with implemented algorithm for automated atrial fibrillation (AF) detection during each ABP measurement. One hundred subjects (mean age 70.6±8.2 [SD] years; men 53%; hypertensives 85%; 17 with permanent AF; 4 paroxysmal AF; and 79 non-AF) had simultaneous 24-hour ABP monitoring and 24-hour Holter monitoring. Among a total of 6410 valid ABP readings, 1091 (17%) were taken in ECG AF rhythm...
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29735632/endothelial-ppar%C3%AE-peroxisome-proliferator-activated-receptor-%C3%AE-is-essential-for-preventing-endothelial-dysfunction-with-aging
#12
T Michael De Silva, Ying Li, Dale A Kinzenbaw, Curt D Sigmund, Frank M Faraci
Little is known about mechanisms that control vascular aging, particularly at the cell-specific level. PPARγ (peroxisome proliferator-activated receptor-γ) exerts protective effects in the vasculature when activated pharmacologically. To gain insight into the cell-specific impact of PPARγ, we examined the hypothesis that genetic interference with endothelial PPARγ would augment age-induced vascular dysfunction. We studied carotid arteries from adult (11.6±0.3 months) and old (24.7±0.6 months) mice with endothelial-specific expression of a human dominant negative mutation in PPARγ driven by the vascular cadherin promoter (E-V290M), along with age-matched, nontransgenic littermates...
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29735631/renal-specific-silencing-of-tnf-tumor-necrosis-factor-unmasks-salt-dependent-increases-in-blood-pressure-via-an-nkcc2a-na-k-2cl-cotransporter-isoform-a-dependent-mechanism
#13
Shoujin Hao, Mary Hao, Nicholas R Ferreri
We tested the hypothesis that TNF (tumor necrosis factor)-α produced within the kidney and acting on the renal tubular system is part of a regulatory mechanism that attenuates increases in blood pressure in response to high salt intake. Intrarenal administration of a lentivirus construct, which specifically silenced TNF in the kidney, did not affect baseline blood pressure. However, blood pressure increased significantly 1 day after mice with intrarenal silencing of TNF ingested 1% NaCl in the drinking water...
May 7, 2018: Hypertension
https://www.readbyqxmd.com/read/29712746/nocturnal-hypertension-new-technology-and-evidence
#14
REVIEW
Kazuomi Kario
No abstract text is available yet for this article.
April 30, 2018: Hypertension
https://www.readbyqxmd.com/read/29712745/impact-of-intensive-versus-standard-blood-pressure-management-by-tertiles-of-blood-pressure-in-sprint-systolic-blood-pressure-intervention-trial
#15
Brian P Shapiro, Walter T Ambrosius, Joseph L Blackshear, William C Cushman, Paul K Whelton, Suzanne Oparil, Srinivasan Beddhu, Jamie P Dwyer, Lisa H Gren, William J Kostis, Michael Lioudis, Roberto Pisoni, Clive Rosendorff, William E Haley
Intensive systolic blood pressure (SBP) control improved outcomes in SPRINT (Systolic Blood Pressure Intervention Trial). Our objective was to expand on reported findings by analysis of baseline characteristics, primary outcomes, adverse events, follow-up blood pressure, and medication use differences by baseline SBP (tertile 1 [T1], <132; tertile 2 [T2], 132-145; and tertile 3 [T3], >145 mm Hg). Participants with higher baseline SBP tertile were more often women and older, had higher cardiovascular risk, and lower utilization of antihypertensive medications, statins, and aspirin...
April 30, 2018: Hypertension
https://www.readbyqxmd.com/read/29712744/vascular-cell-glycocalyx-mediated-vascular-remodeling-induced-by-hemodynamic-environmental-alteration
#16
Jiajia Liu, Hongyan Kang, Xuejiao Ma, Anqiang Sun, Huiqin Luan, Xiaoyan Deng, Yubo Fan
Vascular remodeling induced by hemodynamic stimuli contributes to the pathophysiology of cardiovascular diseases. The importance of vascular cells (endothelial cells and smooth muscle cells) glycocalyx in the mechanotransduction of flow-induced shear stress at the cellular and molecular levels has been demonstrated over the past decade. However, its potential mechanotransduction role in vascular remodeling has triggered little attention. In the present study, a home-made apparatus was used to expose the rat abdominal aorta to sterile, flow or no flow, normal-pressure or high-pressure conditions for 4 days...
April 30, 2018: Hypertension
https://www.readbyqxmd.com/read/29712743/impact-of-pituitary-gonadal-axis-hormones-on-pulmonary-arterial-hypertension-in-men
#17
Wen-Hui Wu, Ping Yuan, Si-Jin Zhang, Xin Jiang, Cheng Wu, Yuan Li, Shao-Fei Liu, Qian-Qian Liu, Jing-Hui Li, Bigyan Pudasaini, Qing-Hua Hu, Jocelyn Dupuis, Zhi-Cheng Jing
The association of sex hormone (estradiol, testosterone, and progesterone) with cardiopulmonary disease has already attracted great attention, especially in pulmonary arterial hypertension (PAH). However, the impact of sex hormones and their pituitary stimulators (follicle-stimulating hormone and luteinizing hormone) on PAH in men remains unclear. We conducted a prospective cohort study recruiting 95 patients with idiopathic PAH from 2008 to 2014 and following up for a median of 65 months for death. Compared with control, abnormal plasma levels of sex hormones were more common in patients with PAH...
April 30, 2018: Hypertension
https://www.readbyqxmd.com/read/29712742/persistent-organochlorine-pollutants-in-plasma-blood-pressure-and-hypertension-in-a-longitudinal-study
#18
Carolina Donat-Vargas, Agneta Åkesson, Andreas Tornevi, Maria Wennberg, Johan Sommar, Hannu Kiviranta, Panu Rantakokko, Ingvar A Bergdahl
Persistent organochlorine pollutants (POPs) have shown to be involved in the atherosclerotic process and to cause endothelial cell dysfunction. To assess longitudinally whether plasma concentrations of different POPs were associated with blood pressure and risk of hypertension in middle-aged women and men. Study subjects were 850 participants in the VIP (Västerbotten Intervention Programme) with 2 blood samples and blood pressure measurements, 10 years apart, during 1990 to 2003 (baseline) and during 2000 to 2013 (follow-up)...
April 30, 2018: Hypertension
https://www.readbyqxmd.com/read/29712741/cystathionine-%C3%AE-lyase-produced-hydrogen-sulfide-controls-endothelial-no-bioavailability-and-blood-pressure
#19
István András Szijártó, Lajos Markó, Milos R Filipovic, Jan Lj Miljkovic, Christoph Tabeling, Dmitry Tsvetkov, Ning Wang, Luiza A Rabelo, Martin Witzenrath, André Diedrich, Jens Tank, Noriyuki Akahoshi, Shotaro Kamata, Isao Ishii, Maik Gollasch
Hydrogen sulfide (H2 S) and NO are important gasotransmitters, but how endogenous H2 S affects the circulatory system has remained incompletely understood. Here, we show that CTH or CSE (cystathionine γ-lyase)-produced H2 S scavenges vascular NO and controls its endogenous levels in peripheral arteries, which contribute to blood pressure regulation. Furthermore, eNOS (endothelial NO synthase) and phospho-eNOS protein levels were unaffected, but levels of nitroxyl were low in CTH-deficient arteries, demonstrating reduced direct chemical interaction between H2 S and NO...
April 30, 2018: Hypertension
https://www.readbyqxmd.com/read/29712740/beneficial-effects-of-high-potassium-contribution-of-renal-basolateral-k-channels
#20
REVIEW
Alexander Staruschenko
No abstract text is available yet for this article.
April 30, 2018: Hypertension
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