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Journal of Affective Disorders

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https://www.readbyqxmd.com/read/28222360/maintenance-therapy-with-second-generation-antipsychotics-for-bipolar-disorder-a-systematic-review-and-meta-analysis
#1
REVIEW
Leif Lindström, Eva Lindström, Mikael Nilsson, Malin Höistad
BACKGROUND: Second generations antipsychotics (SGA) are frequently used for maintenance treatment in bipolar disorder. We systematically reviewed the efficacy and long-term effects of treatment with SGA, regardless of treatment strategy (SGA administered either as monotherapy or as adjunctive therapy), in comparison to placebo, lithium or valproate. Primary outcomes were relapses (mood episode recurrence) and discontinuation. METHOD: Clinical studies were identified through database searching in PubMed, Embase, PsychInfo and Cochrane Library and critically appraised based on the Cochrane Handbook...
February 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28222359/disgust-proneness-predicts-obsessive-compulsive-disorder-symptom-severity-in-a-clinical-sample-of-youth-distinctions-from-negative-affect
#2
Bunmi O Olatunji, Chad Ebesutani, Jingu Kim, Bradley C Riemann, David M Jacobi
BACKGROUND: Although studies have linked disgust proneness to the etiology and maintenance of obsessive-compulsive disorder (OCD) in adults, there remains a paucity of research examining the specificity of this association among youth. METHOD: The present study employed structural equation modeling to examine the association between disgust proneness, negative affect, and OCD symptom severity in a clinical sample of youth admitted to a residential treatment facility (N =471)...
February 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28219028/identifying-women-at-risk-for-sustained-postpartum-anxiety
#3
Cindy-Lee Dennis, Hilary K Brown, Kobra Falah-Hassani, Flavia Casasanta Marini, Simone N Vigod
INTRODUCTION: To describe the prevalence of sustained postpartum anxiety and to develop a multifactorial predictive model to assist in targeted screening procedures. METHODS: In a population-based cohort in a health region near Vancouver, Canada, 522 mothers completed a mailed questionnaire at 1, 4, and 8 weeks postpartum measuring socio-demographic, biological, pregnancy-related, life stressor, social support, obstetric, and maternal adjustment factors. We undertook a sequential logistic regression analysis to develop a multifactorial predictive model of sustained postpartum anxiety, as measured by a State Trait Anxiety Inventory (STAI) score >40 at 1 week and/or 4 weeks, and 8 weeks postpartum...
February 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28213123/risk-of-depression-in-patients-with-uterine-leiomyoma-a-nationwide-population-based-cohort-study
#4
Te-Chun Shen, Chih-Yi Yang, Yu-Jhen Huang, Cheng-Li Lin, Fung-Chang Sung
BACKGROUND: Population-based cohort study investigating the depression risk for patients with uterine leiomyoma (UL) is unavailable. This study investigated the subsequent risk of depression among patients with UL in an Asian population. METHODS: Using data from the National Health Insurance Research Database of Taiwan, we established a cohort with 21,168 patients diagnosed with UL between 2000 and 2010, and a non-UL cohort of 82,108 women without UL matched by age and year of diagnosis...
February 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28213121/determination-of-a-clinically-important-difference-and-definition-of-a-responder-threshold-for-the-ucsd-performance-based-skills-assessment-upsa-in-patients-with-major-depressive-disorder
#5
Philip D Harvey, William Jacobson, Wei Zhong, George G Nomikos, Christina Kurre Olsen, Elizabeth Merikle, Michael Cronquist Christensen
BACKGROUND: This article reports an evaluation of the psychometric properties and clinically important difference (CID) threshold of the UCSD Performance-Based Skills Assessment (UPSA) in major depressive disorder (MDD), using data from a large-scale study of the effects of vortioxetine on cognitive functioning and functional capacity in MDD patients. METHODS: Adults with moderate-to-severe recurrent MDD and self-reported cognitive dysfunction were randomized to 8 weeks of double-blind treatment with vortioxetine 10/20mg QD (flexible), duloxetine 60mg QD, or placebo...
February 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28213122/improvement-of-mindfulness-skills-during-mindfulness-based-cognitive-therapy-predicts-long-term-reductions-of-neuroticism-in-persons-with-recurrent-depression-in-remission
#6
Philip Spinhoven, Marloes J Huijbers, Johan Ormel, Anne E M Speckens
BACKGROUND: This study examined whether changes in mindfulness skills following Mindfulness-based Cognitive Therapy (MBCT) are predictive of long-term changes in personality traits. METHODS: Using data from the MOMENT study, we included 278 participants with recurrent depression in remission allocated to Mindfulness-Based Cognitive Therapy (MBCT). Mindfulness skills were measured with the FFMQ at baseline, after treatment and at 15-month follow-up and personality traits with the NEO-PI-R at baseline and follow-up...
February 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28199893/decreased-cingulate-cortex-activation-during-cognitive-control-processing-in-bipolar-disorder
#7
Staci A Gruber, M Kathryn Dahlgren, Kelly A Sagar, Atilla Gonenc, Lesley Norris, Bruce M Cohen, Dost Ongur, Kathryn E Lewandowski
BACKGROUND: Cognitive deficits are well-documented in patients with bipolar disorder (BPD) and may impact the efficacy of psychotherapy. Cognitive control, a form of executive functioning, is often used therapeutically to shift patients' thoughts and behaviors from automatic, maladaptive responses to adaptive coping strategies. This study examined cognitive control processing in patients with BPD using the Multi-Source Interference Task (MSIT). METHOD: Twenty-nine patients diagnosed with BPD and 21 healthy control (HC) subjects completed the MSIT with concurrent functional magnetic resonance imaging (fMRI)...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28199892/a-prognostic-index-pi-as-a-moderator-of-outcomes-in-the-treatment-of-depression-a-proof-of-concept-combining-multiple-variables-to-inform-risk-stratified-stepped-care-models
#8
Lorenzo Lorenzo-Luaces, Robert J DeRubeis, Annemieke van Straten, Bea Tiemens
BACKGROUND: Prognostic indices (PIs) combining variables to predict future depression risk may help guide the selection of treatments that differ in intensity. We develop a PI and show its promise in guiding treatment decisions between treatment as usual (TAU), treatment starting with a low-intensity treatment (brief therapy (BT)), or treatment starting with a high-intensity treatment intervention (cognitive-behavioral therapy (CBT)). METHODS: We utilized data from depressed patients (N=622) who participated in a randomized comparison of TAU, BT, and CBT in which no statistically significant differences in the primary outcomes emerged between the three treatments...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28192737/a-systematic-review-of-yoga-for-major-depressive-disorder
#9
REVIEW
Holger Cramer, Dennis Anheyer, Romy Lauche, Gustav Dobos
BACKGROUND: The purpose of this review was to investigate the efficacy and safety of yoga interventions in treating patients with major depressive disorder. METHODS: MEDLINE, Scopus, and the Cochrane Library were screened through December 2016. Randomized controlled trials (RCTs) comparing yoga to inactive or active comparators in patients with major depressive disorder were eligible. Primary outcomes included remission rates and severity of depression. Anxiety and adverse events were secondary outcomes...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28192736/evidence-of-the-dissociative-ptsd-subtype-a-systematic-literature-review-of-latent-class-and-profile-analytic-studies-of-ptsd
#10
REVIEW
Maj Hansen, Jana Ross, Cherie Armour
BACKGROUND: The dissociative PTSD (D-PTSD) subtype was first introduced into the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) in 2013. Prior to this, studies using latent profile analysis (LPA) or latent class analysis (LCA), began to provide support for the D-PTSD construct and associated risk factors. This research is important, because dissociative symptoms in the context of PTSD may potentially interfere with treatment course or outcome. The aims of the present study were twofold: to systematically review the LCA and LPA studies investigating support for the D-PTSD construct; and to review the associated research on the risk factors or covariates of D-PTSD in the identified studies...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28189964/the-relationship-between-childhood-trauma-and-the-severity-of-adulthood-depression-and-anxiety-symptoms-in-a-clinical-sample-the-mediating-role-of-cognitive-emotion-regulation-strategies
#11
Hyu Jung Huh, Kyung Hee Kim, Hee-Kyung Lee, Jeong-Ho Chae
BACKGROUND: Childhood trauma is an important factor in adverse mental health outcomes, including depression and anxiety. The purpose of the present study was to evaluate a hypothesized model describing a pathway of childhood trauma and its influence on psychiatric symptoms in patients with depressive disorder. In this model, childhood trauma was positively associated with current depression and anxiety symptoms, which were mediated by a cognitive emotional regulation strategy. METHOD: Patients with depressive disorder (n=585, 266 men, 316 women) completed the Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Childhood Trauma Questionnaire (CTQ), and Cognitive Emotion Regulation Questionnaire (CERQ)...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28189963/ceramides-and-depression-a-systematic-review
#12
REVIEW
Adam Dinoff, Nathan Herrmann, Krista L Lanctôt
BACKGROUND: Major depressive disorder is a significant contributor to global disability and mortality. The mechanisms of depression are vast and not fully understood, and as a result current treatment of depression is suboptimal. Aberrant sphingolipid metabolism has been observed in some cases of depression, specifically alterations in ceramide concentrations. The role of ceramides and other sphingolipids in depression is a novel concept. This review summarizes and evaluates the current state of evidence for a role of ceramides in depression pathophysiology and the potential for novel depression pharmacotherapies targeting ceramide metabolism...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28189965/serum-lipid-levels-in-depression-and-suicidality-the-korea-national-health-and-nutrition-examination-survey-knhanes-2014
#13
Jihoon Oh, Tae-Suk Kim
BACKGROUND: The level of serum lipids has been reported to be associated with depression and suicidality, but the exact relationship between these factors remains controversial. The aim of this study was to investigate the association between lipid levels and depression with suicidality in large sample. METHODS: We examined the association between serum lipid levels and the existence of mild depression measured using Patient Health Questionnaire 9 (PHQ-9) in a national sample of Korean...
February 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28188994/anxiety-disorder-among-rheumatoid-arthritis-patients-insights-from-real-life-data
#14
Abdulla Watad, Nicola L Bragazzi, Mohammad Adawi, Gali Aljadeff, Howard Amital, Doron Comaneshter, Arnon D Cohen, Daniela Amital
BACKGROUND: Psychiatric disorders occur in a considerable proportion of patients with rheumatoid arthritis (RA), often reflecting the difficulties of these patients in coping with a chronic debilitating disorder. AIM OF THE STUDY: To evaluate the proportion of anxiety disorder in RA patients using a large database analysis. METHODS: The study was designed as a case-control population-based study using data from the Clalit Health Services (CHS) database...
February 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28213124/reciprocal-relationships-between-substance-use-and-disorders-and-suicidal-ideation-and-suicide-attempts-in-the-collaborative-study-of-the-genetics-of-alcoholism
#15
Arpana Agrawal, Rebecca Tillman, Richard A Grucza, Elliot C Nelson, Vivia V McCutcheon, Lauren Few, Kenneth R Conner, Michael T Lynskey, Danielle M Dick, Howard J Edenberg, Victor M Hesselbrock, John R Kramer, Samuel Kuperman, John I Nurnberger, Marc A Schuckit, Bernice Porjesz, Kathleen K Bucholz
BACKGROUND: Substance use and misuse and suicidal thoughts and behaviors tend to co-occur. The purpose of this study was to examine whether (a) suicidal ideation and attempt are related to onset of alcohol, nicotine and cannabis use and dependence; (b) early use of alcohol, nicotine and cannabis is associated with onset of suicidal ideation and attempt; and (c) whether these associations persist while controlling for covariates, such as family history of alcohol problems, major depression and other internalizing and externalizing disorders...
February 3, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28187293/assessing-the-contributions-of-childhood-maltreatment-subtypes-and-depression-case-control-status-on-telomere-length-reveals-a-specific-role-of-physical-neglect
#16
John Vincent, Iiris Hovatta, Souci Frissa, Laura Goodwin, Matthew Hotopf, Stephani L Hatch, Gerome Breen, Timothy R Powell
BACKGROUND: Studies have provided evidence that both childhood maltreatment and depressive disorders are associated with shortened telomere lengths. However, as childhood maltreatment is a risk factor for depression, it remains unclear whether this may be driving shortened telomere lengths observed amongst depressed patients. Furthermore, it's unclear if the effects of maltreatment on telomere length shortening are more pervasive amongst depressed patients relative to controls, and consequently whether biological ageing may contribute to depression's pathophysiology...
February 3, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28188993/excess-costs-of-social-anxiety-disorder-in-germany
#17
Judith Dams, Hans-Helmut König, Florian Bleibler, Jürgen Hoyer, Jörg Wiltink, Manfred E Beutel, Simone Salzer, Stephan Herpertz, Ulrike Willutzki, Bernhard Strauß, Eric Leibing, Falk Leichsenring, Alexander Konnopka
BACKGROUND: Social anxiety disorder is one of the most frequent mental disorders. It is often associated with mental comorbidities and causes a high economic burden. The aim of our analysis was to estimate the excess costs of patients with social anxiety disorder compared to persons without anxiety disorder in Germany. METHODS: Excess costs of social anxiety disorder were determined by comparing two data sets. Patient data came from the SOPHO-NET study A1 (n=495), whereas data of persons without anxiety disorder originated from a representative phone survey (n=3213) of the general German population...
February 2, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28161115/corrigendum-to-affective-temperament-profile-in-psoriasis-patients-in-tunisia-using-temps-a-j-affect-disord-151-1-2013-321-324
#18
N Litaiem, S Youssef, K Jabeur, M R Dhaoui, N Doss
No abstract text is available yet for this article.
February 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28161114/corrigendum-to-the-effect-of-psychotherapeutic-interventions-on-positive-and-negative-affect-in-depression-a-systematic-review-and-meta-analysis-j-affect-disord-202-2016-153-162
#19
Nikolaos Boumparis, Eirini Karyotaki, Annet Kleiboer, Stefan G Hofmann, Pim Cuijpers
No abstract text is available yet for this article.
February 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28192765/neurophysiological-correlates-of-suicidal-ideation-in-major-depressive-disorder-hyperarousal-during-sleep
#20
Michael R Dolsen, Philip Cheng, J Todd Arnedt, Leslie Swanson, Melynda D Casement, Hyang Sook Kim, Jennifer R Goldschmied, Robert F Hoffmann, Roseanne Armitage, Patricia J Deldin
BACKGROUND: Suicide is a major public health concern, and a barrier to reducing the suicide rate is the lack of objective predictors of risk. The present study considers whether quantitative sleep electroencephalography (EEG) may be a neurobiological correlate of suicidal ideation. METHODS: Participants included 84 (45 female, mean age=26.6) adults diagnosed with major depressive disorder (MDD). The item that measures thoughts of death or suicide on the Quick Inventory of Depressive Symptomatology (QIDS) was used to classify 47 participants as low suicidal ideation (24 females, mean age=26...
January 26, 2017: Journal of Affective Disorders
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