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International Ophthalmology

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https://www.readbyqxmd.com/read/29752594/late-onset-traumatic-dislocation-of-laser-in-situ-keratomileusis-corneal-flaps-a-case-series-with-many-clinical-lessons
#1
Darren Shu Jeng Ting, Jean-Pierre Danjoux
PURPOSE: To report three cases of late-onset (7-14 years postoperative) traumatic dislocation of laser in situ keratomileusis (LASIK) flaps with epithelial ingrowth that all had delayed surgical intervention. METHODS: A retrospective, interventional case series of three patients who underwent flap repositioning and mechanical debridement of epithelial ingrowth, all after an initial delayed diagnosis/treatment of dislocated LASIK flap. RESULTS: Visual improvement was noted in all three cases following LASIK flap repositioning and debridement of epithelial ingrowth; patient 1 improved from 20/800 corrected-distance-visual-acuity (CDVA) to 20/20 uncorrected-distance-visual-acuity (UDVA) postoperative (14 years post-LASIK, 5-week interval between injury and surgery), patient 2 improved from 20/50 CDVA to 20/20 CDVA (10 years post-LASIK, 4-month interval between injury and surgery) and patient 3 improved from 20/80 CDVA to 20/60 CDVA (7 years post-LASIK, 14-month interval between injury and surgery)...
May 12, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29752593/effects-of-kallidinogenase-in-patients-undergoing-vitrectomy-for-diabetic-macular-edema
#2
Yuki Yoshizumi, Zaigen Ohara, Hitoshi Tabuchi, Hitomi Sumino, Yukiko Maeda, Hideki Mochizuki, Ken Yamane, Yoshiaki Kiuchi
PURPOSE: To evaluate the effectiveness of the combination of vitrectomy with kallidinogenase for diabetic macular edema (DME). METHODS: This study was designed as a prospective, randomized, multicenter study comparing 19 eyes of 19 patients who received 150 units of kallidinogenase administered a day for 52 weeks from the day after vitrectomy (study group) with 20 eyes of 20 patients who received no kallidinogenase (control group). The main outcome measurements included logMAR visual acuity and central foveal thickness (CFT) before surgery and at 3, 6, 9, and 12 months after vitrectomy...
May 12, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29752592/the-rate-of-endophthalmitis-after-pars-plana-vitrectomy-and-its-risk-factors
#3
Seyed Ali Tabatabaei, Mohammad Soleimani, Hadi Vakili, Morteza Naderan, Alireza Lashay, Houshang Faghihi, Mehdi Yaseri
PURPOSE: To study the incidence of endophthalmitis after pars plana vitrectomy, its causative organisms, and visual acuity outcomes. PATIENTS AND METHODS: In this retrospective, comparative study, the medical records of patients with acute-onset postoperative endophthalmitis after pars plana vitrectomy at Farabi Eye Hospital, Tehran, Iran, during a 12-year period between January 2004 and November 2015 were reviewed. To compare the endophthalmitis patients with other cases who underwent pars plana vitrectomy at the same day and also the same operating room, a control group was developed by gathering the data from surgical records...
May 11, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29749568/structural-changes-of-macula-and-optic-disk-of-the-fellow-eye-in-patients-with-nonarteritic-anterior-ischemic-optic-neuropathy
#4
R Duman, G F Yavas, I Veliyev, M Dogan, R Duman
PURPOSE: The aim was to assess the ganglion cell complex (GCC) thickness, retinal nerve fiber layer (RNFL) thickness and optic disk features in the affected eyes (AE) and unaffected fellow eyes (FE) of subjects with unilateral nonarteritic anterior ischemic optic neuropathy (NAION) and to compare with healthy control eyes (CE) using spectral domain-optical coherence tomography (SD-OCT). METHODS: This study included 28 patients and age, sex and refraction-matched 28 control subjects...
May 10, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29749567/ocular-surface-squamous-neoplasia-analysis-based-on-the-8th-american-joint-committee-on-cancer-classification
#5
Swati Singh, Ashik Mohamed, Swathi Kaliki
PURPOSE: To evaluate outcomes of ocular surface squamous neoplasia (OSSN) based on American Joint Committee on Cancer (AJCC), 8th edition classification. METHODS: Retrospective, non-randomized interventional case series of 127 patients (136 eyes) with OSSN. RESULTS: On the basis of the AJCC (eighth edition), OSSN was classified as per T category as Tis (n = 14, 10%), T1 (n = 0), T2 (n = 4, 3%), T3 (n = 113, 83%), and T4 (n = 5, 4%)...
May 10, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29744763/accuracy-of-ultra-wide-field-fundus-ophthalmoscopy-assisted-deep-learning-a-machine-learning-technology-for-detecting-age-related-macular-degeneration
#6
Shinji Matsuba, Hitoshi Tabuchi, Hideharu Ohsugi, Hiroki Enno, Naofumi Ishitobi, Hiroki Masumoto, Yoshiaki Kiuchi
PURPOSE: To predict exudative age-related macular degeneration (AMD), we combined a deep convolutional neural network (DCNN), a machine-learning algorithm, with Optos, an ultra-wide-field fundus imaging system. METHODS: First, to evaluate the diagnostic accuracy of DCNN, 364 photographic images (AMD: 137) were amplified and the area under the curve (AUC), sensitivity and specificity were examined. Furthermore, in order to compare the diagnostic abilities between DCNN and six ophthalmologists, we prepared yield 84 sheets comprising 50% of normal and wet-AMD data each, and calculated the correct answer rate, specificity, sensitivity, and response times...
May 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29744762/functional-and-morphological-assessment-of-ocular-structures-and-follow-up-of-patients-with-early-stage-parkinson-s-disease
#7
Samir Hasanov, Elif Demirkilinc Biler, Ahmet Acarer, Cezmi Akkın, Zafer Colakoglu, Onder Uretmen
PURPOSE: To evaluate and follow-up of functional and morphological changes of the optic nerve and ocular structures prospectively in patients with early-stage Parkinson's disease. MATERIALS AND METHODS: Nineteen patients with a diagnosis of early-stage Parkinson's disease and 19 age-matched healthy controls were included in the study. All participants were examined minimum three times at the intervals of at least 6 month following initial examination. Pattern visually evoked potentials (VEP), contrast sensitivity assessments at photopic conditions, color vision tests with Ishihara cards and full-field visual field tests were performed in addition to measurement of retinal nerve fiber layer (RNFL) thickness of four quadrants (top, bottom, nasal, temporal), central and mean macular thickness and macular volumes...
May 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29744761/microstructural-retinal-regeneration-after-internal-limiting-membrane-flap-surgery-for-repair-of-large-macular-holes-a-1-year-follow-up-study
#8
Max Vieregge, Christophe Valmaggia, Hendrik P N Scholl, Josef Guber
PURPOSE: To evaluate long-term change in functional and structural outcomes after successful repair of large macular holes (MH) with internal limiting membrane (ILM) flap techniques. METHODS: Eleven consecutive patients were reviewed over a 1-year time period after the successful repair of large MH with ILM flap techniques. SD-optical coherence tomography (SD-OCT) images were taken to assess the anatomical outcome after surgery, while the best-corrected visual acuity (BCVA) was tested using Snellen charts to evaluate the functional outcome...
May 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29736691/comparison-of-pain-after-subepithelial-versus-conventional-accelerated-corneal-collagen-cross-linking-for-keratoconus
#9
Shaowei Li, Huatao Xie, Man Xu, Meiyan Li, Chang Liu, Jingliang He, Tian Han, Xingtao Zhou
PURPOSE: To compare the postoperative pain and epithelial healing time in conventional and subepithelial accelerated corneal collagen cross-linking (CXL) for progressive keratoconus. METHODS: The medical records of 27 consecutive patients who underwent accelerated CXL for progressive keratoconus were retrospectively reviewed. Patients were divided into two groups: the conventional (n = 16) and the subepithelial accelerated CXL group (n = 11). Corneal epithelial layers with a diameter of 8...
May 7, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29730856/comparison-of-densitometric-profile-after-deep-lamellar-keratoplasty-with-two-different-techniques-for-treatment-of-keratoconus
#10
Mohammad Ghoreishi, Abolfazl Kashfi, Mohammadreza Peyman, Shahriar Hanjani, Mohaddese Mohammadinia, Mike Straiko
PURPOSE: To compare densitometric outcome of two techniques of deep lamellar keratoplasty using Pentacam HR corneal densitometry software. METHODS: Postoperative outcomes of 31 patients with big bubble (BB) and 28 patients with Melles (M) surgery for the treatment of keratoconus were evaluated. Data were gathered at least 3 months after the removal of all sutures including demographic data, uncorrected distance visual acuity (UCDVA), best spectacle-corrected visual acuity (BSCVA), refraction and endothelial cell count...
May 5, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29728896/nd-yag-laser-for-epithelial-ingrowth-after-laser-in-situ-keratomileusis
#11
Osama Ali Mohammed, Amr Mounir, Amin Aboali Hassan, Alahmady Hamad Alsmman, Engy Mohamed Mostafa
PURPOSE: To evaluate the efficacy of neodymium:yttrium-aluminum-garnet (Nd:YAG) laser for treatment of epithelial ingrowth after laser in situ keratomileusis (LASIK). PATIENTS AND METHODS: Fifty-eight patients with epithelial ingrowth presented to Sohag refractive center, Sohag, Egypt, between January 2015 and March 2017. Only 41 patients (18 females and 23 males, mean age: 33.4 years) involving 41 eyes were indicated for treatment by Nd:YAG laser as the rest of the eyes were only under observation...
May 4, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29721842/pigment-dispersion-syndrome-and-pigmentary-glaucoma-a-review-and-update
#12
Gianluca Scuderi, Maria Teresa Contestabile, Luca Scuderi, Aloisa Librando, Vito Fenicia, Siavash Rahimi
INTRODUCTION: Potential factors influencing stereopsis were investigated in patients with both refractive accommodative esotropia (RAE) and amblyopia. Pigment dispersion syndrome (PDS) is a condition where anomalous iridozonular contact leads to pigment dispersion throughout the anterior segment and the released pigment is abnormally deposited on various ocular structures. CLINICAL PRESENTATION: The clinical presentation of PDS is defined by the presence of pigmented cells on the corneal endothelium, an increase of pigmentation of the trabecular meshwork, and mid-periphery transillumination defects of the iris...
May 2, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29721841/histomorphometric-analysis-of-the-choroid-of-donkeys-buffalos-camels-and-dogs
#13
Ahmed M Kotb, Ismail Abdel-Aziz Ibrahim, Khaled H Aly, Ahmed E Zayed
AIM: The present study was carried out to investigate the morphological and histomorphometric characters of choroid in donkeys, buffalos, camels and dogs. RESULTS: The findings of the study revealed that, macroscopically, the choroid was consisted of two areas in all studied animals, except in camel which consists of one area. Histologically, the choroid consists of five layers. Interestingly, the anterior borders of all investigated animals were free of pigments except in camel...
May 2, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29713855/case-report-acute-hydrops-and-spontaneous-corneal-perforation-in-a-patient-with-keratoconus-treated-with-colchicine-for-familial-mediterranean-fever
#14
Assaf Hilely, Guy Kleinmann
PURPOSE: To report a rare case of spontaneous corneal perforation after hydrops in keratoconus patients who suffer from familial Mediterranean fever and was treated systemically with Colchicine. METHODS: Case report. RESULTS: We report a case of a 30-year-old male with keratoconus and familial Mediterranean fever treated with colchicine, presented with acute hydrops in his left eye, which progressed to a spontaneous corneal perforation. Attempts to treat the perforation with cyanoacrylate glue failed, and he underwent penetrating keratoplasty with an excellent visual outcome...
April 30, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29705893/a-study-of-changes-in-levator-muscle-in-congenital-ptosis
#15
Abhidnya Surve, M C Sharma, Neelam Pushker, M S Bajaj, Rachna Meel, Seema Kashyap
PURPOSE: To study microscopic and ultrastructural changes of levator palpebrae superioris (LPS) muscle in congenital ptosis. METHODS: In this prospective observational study, LPS muscle was studied in 77 eyelids with congenital ptosis; 35-simple congenital ptosis (SCP), 12-Marcus Gunn jaw winking phenomenon (MGJWP), and 30-blepharophimosis epicanthus inversus syndrome (BPES). Light microscopy, enzyme histochemistry, immunohistochemistry and electron microscopy were performed, and results were analyzed...
April 28, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29705892/the-ophthalmic-diagnosis-and-management-of-four-siblings-with-werner-syndrome
#16
C Lyons, D Gallagher, T McSwiney, E McElnea, F Kinsella
INTRODUCTION: Werner syndrome is a rare autosomal recessive disorder caused by mutations in the Werner syndrome WRN gene, on chromosome 8. Those affected manifest early the features of ageing. DISCUSSION: Cataract surgery is prone to post-operative complications in those with Werner syndrome. The development of cystoid macular oedema (CMO) is likely multifactorial. Patients with WS have diabetes mellitus type 2 which can contribute to macular oedema. There is a deposition of abnormal WRN proteins in the macula which also predisposes to macular oedema...
April 28, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29705891/keratomycosis-due-to-tintelnotia-destructans-refractory-to-common-therapy-treated-successfully-with-systemic-and-local-terbinafine-in-combination-with-polyhexamethylene-biguanide
#17
Wolfgang J Behrens-Baumann, Wolfram Hofmüller, Ina Tammer, Kathrin Tintelnot
PURPOSE: To report on a wearer of rigid gas-permeable contact lenses with a keratomycosis due to Tintelnotia-a new genus of Phaeosphaeriaceae-treated with terbinafine and polyhexamethylene biguanide. METHODS: Chart review of a patient with fungal keratitis treated additionally with systemic and topical terbinafine 0.25% after symptoms increased under conventional antimycotic therapy with voriconazole. Antifungal susceptibility had been tested in vitro. RESULTS: After starting an additional treatment with systemic and topical terbinafine, the severe corneal infection was sufficiently resolved...
April 28, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29704132/hook-and-flip-technique-for-phacoemulsification-in-non-rotating-nuclei-and-posterior-polar-cataracts
#18
Shikha Gupta, Harathy Selvan, Sudarshan Khokhar
PURPOSE: We put forward a physical levitation method to hook and flip the chopped nuclear fragments that could not be solely drawn by vacuum during phacoemulsification, due to various reasons such as a non-rotating nuclei or posterior polar cataracts where hydrodissection was unsuccessful or contra-indicated, respectively. METHOD: A Sinskey hook is insinuated through the crack of the divided nuclei into a plane behind the nuclear pie to 'hook and flip' the chopped piece, heading it towards the phacoemulsification probe...
April 27, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29704131/factors-influencing-stereopsis-in-patients-with-both-refractive-accommodative-esotropia-and-amblyopia
#19
Burçin Çakır, Özlem Bursalı, Sedat Özmen, Nilgün Özkan Aksoy, Tural Babashli, Gursoy Alagöz
PURPOSE: Potential factors influencing stereopsis were investigated in patients with both refractive accommodative esotropia (RAE) and amblyopia. MATERIALS AND METHODS: A retrospective chart review was performed to find out all patients with the diagnosis of both RAE and amblyopia. Patients are classified into two groups: group 1 (with stereopsis) and group 2 (without stereopsis). Onset age of RAE, history of strabismus in family members, time of amblyopia treatment, mean spherical equivalent, anisometropia, ocular movement disorders, especially, overaction of inferior oblique (IO) muscle, visual acuity difference (VAD) between eyes, best-corrected visual acuity (BCVA) levels of amblyopic and normal eyes and the presence of alternation of fixation (AOF) were investigated as possible factors...
April 27, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29704130/recurrent-corneal-erosion-caused-by-retained-sutures-in-blepharoplasty
#20
I-Hsin Ma, Bo-I Kuo, Yu-Chih Hou
PURPOSE: To present recurrent corneal erosion (RCE) caused by late suture exposure after blepharoplasty. METHODS: Four patients who have unilateral RCE were found to have previous blepharoplasty. The RCE was associated with late suture exposure. The clinical courses, characteristics, methods to identify the suture exposure and treatment were presented. RESULTS: The clinical presentations including local erosion of upper bulbar conjunctiva, corneal abrasion lines, local corneal epithelial defects with rough border, and subepithelial opacity were noticed in all four patients...
April 27, 2018: International Ophthalmology
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