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International Ophthalmology

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https://www.readbyqxmd.com/read/29442246/cataract-surgery-in-patients-with-glaucoma-drainage-implants-the-hooked-tube-technique
#1
Juha Välimäki
PURPOSE: Cataract surgery has been reported to adversely affect the IOP control in eyes with the glaucoma drainage implant (GDI). One reason might be the flow of lens debris/viscoelastic material through the GDI tube into the bleb. This pilot study was conducted to determine the clinical results of a novel technique for temporary occlusion of the GDI tube with an iris retractor hook during phacoemulsification. METHODS: Retrospective analysis of 15 patients (control group) who underwent phacoemulsification between January 2005 and December 2010 and 17 patients (treatment group) who underwent phacoemulsification with the hooked tube technique between January 2011 and April 2016 with a minimum 1-year follow-up...
February 13, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29442245/retrobulbar-and-intraocular-blood-flow-in-anterior-ischaemic-optic-neuropathy-are-linked-to-the-functional-impairment
#2
David Kuerten, Matthias Fuest, Marion Bienert, Niklas Plange
PURPOSE: Evaluation of ocular haemodynamics in patients with acute non-arteritic anterior ischaemic optic neuropathy (NAION) by colour Doppler imaging and fluorescein angiography and correlation of blood flow parameters to visual field loss and visual acuity. METHODS: Blood flow velocities (peak systolic velocity (PSV), end-diastolic velocity (EDV)) of the ophthalmic artery (OA), central retinal artery (CRA) and nasal and temporal posterior ciliary arteries (PCAs) were measured via colour Doppler imaging...
February 13, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29435797/phacoemulsification-cataract-surgery-in-patients-receiving-novel-oral-anticoagulant-medications
#3
Janice J C Cheung, Shasha Liu, Kenneth K W Li
INTRODUCTION: An increasing number of patients are taking novel oral anticoagulant (NOAC) medication, making perioperative management in phacoemulsification surgery an important issue. This study reports the haemorrhagic complications of NOAC in phacoemulsification surgery. DESIGN: Retrospective case study over a 4-year period. METHODS: Consecutive cases receiving NOAC during the time of phacoemulsification were reviewed. Patients were either advised to continue medications (continued group) or withhold medications before surgery (withheld group)...
February 13, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29435796/retinal-single-layer-analysis-with-optical-coherence-tomography-shows-inner-retinal-layer-thinning-in-huntington-s-disease-as-a-potential-biomarker
#4
Duygu Gulmez Sevim, Metin Unlu, Murat Gultekin, Cagatay Karaca
PURPOSE: There have been ongoing clinical trials of therapeutic agents in Huntington's disease (HD) which requires development of reliable biomarkers of disease progression. There have been studies in the literature with conflicting results on the involvement of retina in HD, and up to date there is not a study evaluating the single retinal layers in HD. We aimed to evaluate the specific retinal changes in HD and their usability as potential disease progression markers. METHODS: This cross-sectional study used spectral-domain optical coherence tomography with automatic segmentation to measure peripapillary retinal nerve fiber layer (pRNFL) thickness and the thickness and volume of retinal layers in foveal scans of 15 patients with HD and 15 age- and sex-matched controls...
February 12, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29429144/results-of-ethanol-assisted-epithelium-on-corneal-cross-linking-with-and-without-intrastromal-corneal-ring-implantation
#5
Orhan Ayar, Orkun Muftuoglu, Mehmet Orcun Akdemir, Mehmet Cuneyt Ozmen
PURPOSE: To evaluate the topographic, refractive, and pachymetric changes after ethanol-assisted transepithelial corneal cross-linking (CXL) to stabilize progression of keratoconus (KC). PATIENTS AND METHODS: This study retrospectively evaluated the long-term topographic, refractive, and pachymetric changes in patients diagnosed with KC who underwent corneal cross-linking and/or intrastromal corneal ring segment (ICRS) implantation. The subjects were divided into three groups, corresponding to eyes treated with CXL alone (group 1), CXL and ICRS at the same time (group 2), and CXL after ICRS implantation (group 3)...
February 10, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29426968/clinical-experience-with-urgent-tube-shunt-implantation-through-the-ciliary-sulcus-in-phakic-eyes
#6
Adam J Weiner, Yotam Weiner, Melissa L Severson, Asher Weiner
PURPOSE: To review the clinical course and outcomes of 3 phakic, ischemic, and inflamed eyes in which we performed urgent tube shunt implantation through the ciliary sulcus without lensectomy. METHODS: This is a retrospective interventional case series. Three eyes of 3 diabetic patients with uncontrolled severe neovascular glaucoma, shallow anterior chambers with closed angles and poor view to the posterior segment, where concomitant lensectomy was not recommended due to uncontrolled uveitis and ischemia, underwent tube shunt implantation through the ciliary sulcus...
February 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29426967/bleb-related-infections-and-long-term-follow-up-after-trabeculectomy
#7
J Luebke, M Neuburger, J F Jordan, T Wecker, D Boehringer, B Cakir, T Reinhard, A Anton
PURPOSE: Bleb-related infections are serious complications after trabeculectomy. They can be limited to the bleb or disseminate and lead to endophthalmitis. We herein report on all bleb-related infections that have been diagnosed at the Eye Center of the University of Freiburg, Germany, since 1999. METHODS: We reviewed a total of 1816 consecutive trabeculectomies that were performed at our hospital between the years 1999 and 2014 (353 without and 1463 with intraoperative application of mitomycin C)...
February 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29426966/multi-viral-canaliculitis-case-report-and-review-of-literature
#8
Mohammad Javed Ali, Joveeta Joseph, Shweta Gupta, Sai Jeevana Madhuri Guda
AIM: To report an atypical case of multiple viruses causing canaliculitis. METHODS: Case report of a young female presenting with atypical course of refractory unilateral canaliculitis with complete mid-bicanalicular obstructions. Canalicular scrapings were subjected to immunofluorescence techniques and polymerase chain reactions to identify the viruses. RESULTS: Investigations revealed a canaliculitis of multi-viral etiology; herpes simplex virus and varicella zoster virus...
February 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29423786/comparison-of-arms2-loc387715-a69s-and-cfh-y402h-risk-effect-in-wet-type-age-related-macular-degeneration-a-meta-analysis
#9
REVIEW
Mohammad Hossein Jabbarpoor Bonyadi, Mehdi Yaseri, Homayoun Nikkhah, Mortaza Bonyadi, Rahman Nazari, Masoud Soheilian
PURPOSE: We designed this meta-analysis to pool studies which have analyzed both CFH (Y402H or I62V) and ARMS2 A69S in the same samples to compare the effect of CFH and ARMS2 in neovascular AMD. METHODS: Relevant studies identified and reviewed separately in order to select those for inclusion. Included studies had genotype data of studied groups for both ARMS2 A69S and CFH. To modify the heterogeneity in the variables, we used random effects model. Meta-analysis was performed using STATA...
February 8, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29423785/damage-to-the-inferior-oblique-muscle-branch-of-the-oculomotor-nerve-a-complication-during-orbital-fat-decompression
#10
Yasuhiro Takahashi, Hirohiko Kakizaki
PURPOSE: To present patients who suffered damage to the inferior oblique muscle branch of the oculomotor nerve during orbital fat decompression. METHODS: This study was a retrospective chart review of all patients who underwent orbital decompression surgery between April 2009 and June 2016 by the authors. RESULTS: Among 414 sides from 226 consecutive patients who underwent orbital decompression, the inferior oblique muscle branch was injured in two sides (0...
February 8, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29423784/ocular-surface-squamous-neoplasia-in-a-setting-of-fungal-keratitis-a-rare-co-occurrence
#11
Swati Singh, Ruchi Mittal, Purvasha Narang, Vikas Mittal
PURPOSE: To describe a rare co-occurrence of ocular surface squamous neoplasia (OSSN) in a patient with microbial keratitis. METHODS: Case report. RESULTS: We describe a 68-years female who developed ocular surface squamous neoplasia (OSSN) in an eye with culture proven severe fungal keratitis of 5 months duration, which progressed to endophthalmitis. She was managed with extended enucleation for left eye. Histopathology examination was consistent with squamous cell carcinoma of ocular surface with no corneal stromal/scleral/anterior chamber involvement...
February 8, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29423783/peyronie-s-disease-and-dupuytren-s-contracture-secondary-to-topical-timolol
#12
Huw Oliphant, Pieter Gouws
INTRODUCTION: Topical beta-blockers are a proven and safe medication used in the treatment of glaucoma and ocular hypertension. Local and systemic side effects are, however, well documented. Systemic side effects can include severe cardio-respiratory impairment, endocrine dysfunction, as well as headache and hyper-somnolence. Disorders involving fibrosis such as Peyronie's disease, Dupuytren's contracture, and retroperitoneal fibrosis are rarely described in the literature. CASE REPORT: We describe a case of a 55-year-old male patient undergoing treatment for ocular hypertension with topical timolol 0...
February 8, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29423782/deep-blue-dot-corneal-degeneration-confocal-characteristics
#13
Harathy Selvan, Archita Singh, Radhika Tandon
PURPOSE: To discuss the clinical features, differential diagnosis and the novel confocal microscopic findings noted in the rare 'deep blue dot corneal degeneration'. METHODS: Observational case report. RESULTS: Slit-lamp biomicroscopic examination revealed bilateral, numerous, circular to oval discrete blue opacities at the level of deep stroma and fine grey linear opacities at the level of mid to deep stroma. Confocal microscopy demonstrated two types of corresponding hyper-reflective extracellular lesions: oval deposit-like, most concentrated at a depth of 430-480 µ and needle-like at the depth 330-370 µ...
February 8, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29417445/a-rating-scale-is-a-proper-method-to-evaluate-changes-in-quality-of-life-due-to-dry-eye-symptoms
#14
Wenwen Xue, Xian Xu, Haidong Zou
PURPOSE: To determine which utility value assessment method is more suitable to evaluate changes in the quality of life due to dry eye symptoms. METHODS: Dry eye outpatients with a presenting visual acuity of 20/25 or better in the worse-seeing eye were recruited. Presenting distance visual acuity, tear film break-up time, Schirmer I test and fluorescein were assessed. The severity of dry eye symptoms was assessed using the Ocular Surface Disease Index (OSDI), and utility values were measured using the time trade-off (TTO), standard gamble (SG1 and SG2) and rating scale (RS) methods...
February 7, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29417444/corneal-perforation-after-noncontact-tonometry-in-patients-with-active-recurrent-herpes-simplex-keratitis-case-report
#15
Napaporn Tananuvat, Atitaya Apivatthakakul, Chulaluck Tangmonkongvoragul
PURPOSE: To report iatrogenic complications and to review the potential complications caused by noncontact tonometry (NCT) in related literature. METHODS: This case report describes two cases of active recurrent herpes simplex keratitis (HSK) on top of a thin corneal scar. The cornea was perforated by the air pulse from the NCT, resulting in an air bubble in the anterior chamber. RESULTS: Both patients were diagnosed with active recurrent necrotizing stromal HSK on top of a thinned corneal scar after previous therapeutic treatment involving tissue adhesive glue with a bandage contact lens (BCL) to treat a perforated cornea...
February 7, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29417443/the-outcomes-of-subtotal-vitrectomy-in-macular-surgeries-a-single-surgeon-case-series
#16
Abdullah Ozkaya, Gurkan Erdogan, Beril Tulu, Hatice Nur Tarakcioglu
PURPOSE: To investigate the outcomes of subtotal vitrectomy in epiretinal membrane (ERM) and idiopathic macular hole (IMH) surgeries. METHODS: The patients who underwent vitrectomy for primary ERM and IMH were included. After the truncation of posterior hyaloid, cortical vitreous was incompletely removed and anterior vitreous was left in place. The main outcome measure was the complications of the surgical technique during the postoperative 12 months of follow-up...
February 7, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29411260/a-case-of-conjunctival-malt-lymphoma-successfully-treated-with-solely-extended-rituximab-therapy
#17
Hande Celiker, Ebru Toker, Isik Kaygusuz Atagunduz
PURPOSE: Primary ocular adnexal lymphomas are cured by radiotherapy; however, complications are frequent and relapses may occur. In this case, we aimed to report the efficacy and safety of extended systemic rituximab (anti-CD 20 monoclonal antibody) therapy of conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma. METHODS: In the standard regimen, rituximab is used as four consecutive weekly infusions of 375 mg/m2 in patients with low-grade lymphomas. We treated a patient who had bilateral conjunctival MALT lymphoma with rituximab 375 mg/m2 intravenously once weekly for 10 weeks as a first-line therapy...
February 6, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29411259/intravitreal-aflibercept-for-the-treatment-of-choroidal-neovascularization-associated-with-rubella-retinopathy
#18
Hasan Kiziltoprak, Esat Yetkin, Kemal Tekin, Mustafa Koc, İrfan Akalin, Mehmet Yasin Teke
PURPOSE: To report a case of choroidal neovascularization (CNV) associated with rubella retinopathy (RR) treated with intravitreal aflibercept. CASE PRESENTATION: A 15-year-old girl presented a complaint of visual decrease in her left eye. She had a history of hearing decrease since she was 1 year old in addition to patent ductus arteriosus. On ocular examination, the best corrected visual acuity (BCVA) was 20/20 in the right eye and 20/400 in the left eye. Dilated fundus examinations revealed a classic salt-and-pepper appearance in both eyes and a whitish subretinal lesion with retinal hemorrhages in the left macula...
February 6, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29404861/therapeutic-potential-of-curcumin-in-major-retinal-pathologies
#19
REVIEW
Krishi V Peddada, A'sha Brown, Vivek Verma, Marcella Nebbioso
PURPOSE: The retina is continually exposed to free radicals from its rich blood supply, numerous mitochondria, and photons of light which strike its surface. Most pathological processes that take place in the retina, such as inflammation, cell apoptosis, or angiogenesis, can hence involve free radicals directly or indirectly.  Since inflammatory and oxidative stress pathways underlie retinal pathology, compounds that address these factors are therefore natural choices for treatment. This review article summarizes and provides commentary on curcumin's therapeutic potential use in ophthalmology with principal focus on retinal dosorders...
February 5, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29404860/ranibizumab-versus-aflibercept-for-the-treatment-of-vascularized-pigment-epithelium-detachment-due-to-age-related-macular-degeneration
#20
Alexandros Rouvas, Irini Chatziralli, Angeliki Androu, Panagiota Mpougatsou, Dimitrios Alonistiotis, Maria Douvali, Stamatina A Kabanarou, Panagiotis Theodossiadis
PURPOSE: To compare the efficacy and safety of two intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents, ranibizumab and aflibercept, for the treatment of vascularized pigment epithelium detachment (vPED) due to age-related macular degeneration (AMD) in a follow-up time of 12 months. METHODS: Participants in this study were 71 patients (71 eyes) with vPED due to AMD, who were treated with intravitreal 0.5 mg ranibizumab (n = 38) or 2.0 mg aflibercept (n = 33) and had at least 12-month follow-up...
February 5, 2018: International Ophthalmology
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