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Journal of Ethnopharmacology

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https://www.readbyqxmd.com/read/29471086/gastroprotective-effect-of-ethanol-extracts-of-cladodes-and-roots-of-pilosocereus-gounellei-a-weber-ex-k-schum-bly-ex-rowl-cactaceae-on-experimental-ulcer-models
#1
Glaubert A Sousa, Irisdalva S Oliveira, Francilene V Silva-Freitas, Ana Flávia S C Viana, Benedito P S Neto, Francisco Valmor M Cunha, Rodrigo L G Gonçalves, Antônio Carlos M Lima Filho, Maurício P M Amaral, Rita de Cássia M Oliveira, Pedro D Fernandes, Jéssica K S Maciel, Tânia Maria S da Silva, Maria de Fátima V Souza, Francisco A Oliveira
ETHNOPHARMACOLOGICAL RELEVANCE: Pilosocereus gounellei Cactaceae), popularly known as "xique xique", is a species native from Caatinga region of Northeast Brazil, which is used by traditional communities in folk medicine for a variety of health problems, especially inflammatory processes and gastritis. AIM OF THE STUDY: The present study investigates the possible gastric antiulceractivity of ethanol extracts obtained from the cladodes and roots of Pilosocereus gounellei (EECPG and EERPG, respectively) and mechanisms of action underlying this effect...
February 19, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29471085/houttuynia-cordata-polysaccharides-ameliorate-pneumonia-severity-and-intestinal-injury-in-mice-with-influenza-virus-infection
#2
Haiyan Zhu, Xiaoxiao Lu, Lijun Ling, Hong Li, Yingye Ou, Xunlong Shi, Yan Lu, Yunyi Zhang, Daofeng Chen
ETHNOPHARMACOLOGICAL RELEVANCE: Hottuynia cordata is an important traditional Chinese medicine for the treatment of respiratory diseases including bacterial and viral infections. Polysaccharides isolated from Houttuynia cordata (HCP), as its main ingredients, have been demonstrated to ameliorate the LPS-induced acute lung injury in mice. The study aimed to determine the protective effects of HCP on multiple organ injury in influenza A virus (IAV) H1N1 infected mice and its primary mechanisms in anti-inflammation and immune regulation...
February 19, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29462700/eugenia-brasiliensis-leaves-extract-attenuates-visceral-and-somatic-inflammatory-pain-in-mice
#3
Róli R Simões, Scheila I Kraus, Igor S Coelho, Daniela Dal-Secco, Diogo A Siebert, Gustavo A Micke, Michele D Alberton, Adair R S Santos
ETHNOPHARMACOLOGICAL RELEVANCE: Eugenia brasiliensis Lam. (Myrtaceae) is a Brazilian tree distributed throughout Atlantic rain forest, since Bahia until Santa Catarina state, and is popularly known as "grumixaba, grumixameira, cumbixaba, ibaporoiti, and cereja-brasileira". The bark and leaves of Eugenia brasiliensis are used in folk medicine as adstringent, diuretic, energizing, anti-rheumatic and anti-inflammatory. This study aimed at investigating the chemical composition, antinociceptive and anti-inflammatory effect of the hydroalcoholic extract of Eugenia brasiliensis (HEEb)...
February 17, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29462699/effect-of-eucommia-ulmoides-oliv-gynostemma-pentaphyllum-thunb-makino-and-curcuma-longa-l-on-th1-and-th2-cytokine-responses-and-human-leukocyte-antigen-dr-expression-in-peripheral-blood-mononuclear-cells-of-septic-patients
#4
Huang-Pin Wu, Yin-Ku Lin
ETHNOPHARMACOLOGICAL RELEVANCE: Many traditional Chinese medicines (TCM), such as Eucommia ulmoides Oliv., Gynostemma pentaphyllum (Thunb.) Makino, and Curcuma longa L., have been reported to have various immune-modulatory effects. AIM OF THE STUDY: To determine the effects of extracts from these three TCM on type 1T help (Th1)- and Th2-cytokine responses and human leukocyte antigen (HLA)-DR expression in peripheral blood mononuclear cells (PBMCs) obtained from septic patients...
February 17, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29462698/piper-sarmentosum-roxb-confers-neuroprotection-on-beta-amyloid-a%C3%AE-induced-microglia-mediated-neuroinflammation-and-attenuates-tau-hyperphosphorylation-in-sh-sy5y-cells
#5
Emilia Tze Ying Yeo, Kelly Wang Ling Wong, Mun Ling See, Ka Yan Wong, Sook Yee Gan, Elaine Wan Ling Chan
ETHNOPHARMACOLOGICAL RELEVANCE: Piper sarmentosum Roxb. (PS), belonging to Piperaceae family, is an edible plant with medicinal properties. It is traditionally used by the Malays to treat headache and boost memory. Pharmacological studies revealed that PS exhibits anti-inflammatory, anti-oxidant, anti-acetylcholinesterase, and anti-depressant-like effects. In view of this, the present study aimed to investigate the anti-inflammatory actions of PS and its potential neuroprotective effects against beta-amyloid (Aβ)-induced microglia-mediated neurotoxicity...
February 17, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29458147/sessein-and-isosessein-with-anti-inflammatory-antibacterial-and-antioxidant-activity-isolated-from-salvia-sessei-benth
#6
Abraham Gómez-Rivera, Manasés González-Cortazar, Maribel Herrera-Ruíz, Alejandro Zamilpa, Verónica Rodríguez-López
ETHNOPHARMACOLOGICAL RELEVANCE: Salvia sessei Benth, popularly known as "pipilolxochitl" or "sabanito", is a plant utilized in Mexico in traditional medicine for the treatment of erysipela. To date, only one report, to our knowledge, has been found in which a royleanone-type diterpene of the aerial parts of the species was isolated but, again to our knowledge, studies have not been conducted on the pharmacological activity of extracts and compounds isolated from this plant...
February 16, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29458146/enhanced-anticancer-effects-of-scutellaria-barbata-d-don-in-combination-with-traditional-chinese-medicine-components-on-non-small-cell-lung-cancer-cells
#7
Qian Wang, Narayan Acharya, Zhongwei Liu, Xianmei Zhou, Meghan Cromie, Jia Zhu, Weimin Gao
ETHNOPHARMACOLOGICAL RELEVANCE: Experience-based herbal medicine as a complementary to modern western medicine has triggered an array of studies in quest of novel anticancer drugs. Scutellaria barbata D. Don (SB) is commonly used to treat different types of cancers, but its molecular mechanism of action is not clearly understood. In this study, we attempted to elucidate the mode of action of a traditional Chinese medicine prescription with a total of 14 components, named Lian-Jia-San-Jie-Fang (LJSJF, in Chinese), where SB works as the "principle" against non-small cell lung cancer (NSCLC) cells...
February 16, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29454914/substituting-one-paris-for-another-in-vitro-cytotoxic-and-in-vivo-antitumor-activities-of-paris-forrestii-a-substitute-of-paris-polyphylla-var-yunnanensis
#8
Yue-Hu Wang, Min Shi, Hong-Mei Niu, Jun Yang, Meng-Yuan Xia, Ji-Feng Luo, Ying-Jie Chen, Yi-Ping Zhou, Heng Li
ETHNOPHARMACOLOGICAL RELEVANCE: Chong-lou (Paris polyphylla var. yunnanensis or P. polyphylla var. chinensis) is traditionally used as an anticancer medicine in China. It is also the material basis of some Chinese patent anticancer medicines, such as Gan-Fu-Le capsules, Bo-Er-Ning capsules, Lou-Lian capsules, Ruan-Jian oral liquid, and Qi-Zhen capsules. P. forrestii, a substitute for Chong-lou, is planted at a large scale in the Yunnan Province of China. AIM OF THE STUDY: To clarify the active chemical constituents of P...
February 15, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29454913/restoring-th17-treg-balance-via-modulation-of-stat3-and-stat5-activation-contributes-to-the-amelioration-of-chronic-obstructive-pulmonary-disease-by-bufei-yishen-formula
#9
Peng Zhao, Jiansheng Li, Yange Tian, Jing Mao, Xuefang Liu, Suxiang Feng, Junzi Li, Qingqing Bian, Huige Ji, Lanxi Zhang
ETHNOPHARMACOLOGY RELEVANCE: Bufei Yishen formula (BYF), a Traditional Chinese Medicine (TCM), has been extensively applied in clinical treatment of chronic obstructive pulmonary disease (COPD) and provides an effective treatment strategy for the syndrome of lung-kidney qi deficiency in COPD patients. Here, we investigated its anti-COPD mechanism in COPD rats in relation to the balance between T helper (Th) 17 cells and regulatory T (Treg) cells. METHODS: Rat model of cigarette smoke- and bacterial infection-induced COPD was established, and orally treated with BYF for 12 consecutive weeks...
February 15, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29454912/anticancer-effect-of-petroleum-ether-extract-from-bidens-pilosa-l-and-its-constituent-s-analysis-by-gc-ms
#10
Yiwei Shen, Zhouliang Sun, Peiying Shi, Gang Wang, Youjia Wu, Shaoguang Li, Yanjie Zheng, Liying Huang, Liqing Lin, Xinhua Lin, Hong Yao
ETHNOPHARMACOLOGICAL RELEVANCE: Bidens pilosa L, belonging to the family of Acanthaceae, has been used as an anticancer medicine in folk in China. In our preliminary experiments, the petroleum ether extract from B. pilosa showed good cytotoxic activity to human lung cancer A549 cell. However, to date, it's lack of the further study on antitumor effect, mechanism and active substances composition of the petroleum ether extract of B. pilosa. AIM OF THE STUDY: The study aimed to evaluate the anti-lung cancer efficacy of the petroleum ether extract from B...
February 15, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29454024/development-of-an-in-vitro-screening-method-of-acute-cytotoxicity-of-the-pyrrolizidine-alkaloid-lasiocarpine-in-human-and-rodent-hepatic-cell-lines-by-increasing-susceptibility
#11
Kristina Forsch, Verena Schöning, Lucia Disch, Beate Siewert, Matthias Unger, Jürgen Drewe
ETHNOPHARMACOLOGICAL RELEVANCE: Pyrrolizidine alkaloids (PAs) are secondary plant ingredients formed in many plant species to protect against predators. PAs are generally considered acutely hepatotoxic, genotoxic and carcinogenic. Up to now, only few in vitro and in vivo investigations were performed to evaluate their relative toxic potential. AIM OF THE STUDY: The aim was to develop an in vitro screening method of their cytotoxicity. MATERIALS AND METHODS: Human and rodent hepatocyte cell lines (HepG2 and H-4-II-E) were used to assess cytotoxicity of the PA lasiocarpine...
February 14, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29452141/a-rich-source-of-potential-bioactive-compounds-with-anticancer-activities-by-catharanthus-roseus-cambium-meristematic-stem-cell-cultures
#12
So Hyun Moon, Muthuraman Pandurangan, Doo Hwan Kim, Jelli Venkatesh, Rahul V Patel, Bhupendra M Mistry
ETHNOPHARMACOLOGICAL IMPORTANCE: Catharanthus roseus (L.) G. Don. is an important medicinal plant with rich sources of remarkable health benefits consisting more than 100 alkaloids and significant amounts of bioactive compounds, which have been widely used as a folk medicine for treatment of several pathologies. THE AIM OF THE STUDY: In the present study, we isolated and cultured innately undifferentiated cambium meristematic cells (CMCs), which were observed stable cell growth, enhancement of bioactive compounds from C...
February 13, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29447950/ethnobotanical-and-ethnomedicinal-studies-in-baluchi-tribes-a-case-study-in-mt-taftan-southeastern-iran
#13
Tahereh Maleki, Hossein Akhani
ETHNOBOTANICAL RELEVANCE: From ancient times, the applied use of herbs has been common among indigenous people throughout the world. The present survey is a regional ethnobotanical study of Baluchi tribes living in the Mt. Taftan area, Sistan and Baluchistan Province, southeastern Iran. The aim of this study was to document all traditional knowledge and analyze the medicinal plants used in area and also to identify significant plant species for future pharmacological study. MATERIALS AND METHODS: Local knowledge was obtained through semi structured and open interviews, in which 51 informants were interviewed...
February 12, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29447949/protective-effects-of-alpinae-oxyphyllae-fructus-extracts-on-lipopolysaccharide-induced-animal-model-of-alzheimer-s-disease
#14
Yunlong Wang, Mengshi Wang, Kaiyue Fan, Tongde Li, Tingxu Yan, Bo Wu, Kaishun Bi, Ying Jia
ETHNOPHARMACOLOGICAL RELEVANCE: Alpinae Oxyphyllae Fructus (AOF) with warming and tonifying the kidney and spleen, anti-salivation, anti-polyuria and anti-diarrhea functions is the dried ripe fruits of Alpinia oxyphylla Miq. (Zingiberaceae). As a traditional Chinese medicine, its application history is very long. AIMS OF THE STUDY: The purpose of our study is to investigate the effects of different solvent extracts from AOF on lipopolysaccharide (LPS)-induced animal model of Alzheimer's disease (AD) to elucidate the traditional medical theories with modern pharmacological methods and provide a reference for further clarifying its active components and mechanisms...
February 12, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29432856/aqueous-extracts-from-uncaria-tomentosa-willd-ex-schult-dc-reduce-bronchial-hyperresponsiveness-and-inflammation-in-a-murine-model-of-asthma
#15
Bruna Cestari de Azevedo, Lucas Junqueira de Freitas Morel, Fábio Carmona, Thiago Mattar Cunha, Silvia Helena Taleb Contini, Piero Giuseppe Delprete, Fernando Silva Ramalho, Eduardo Crevelin, Bianca Waléria Bertoni, Suzelei de Castro França, Marcos de Carvalho Borges, Ana Maria Soares Pereira
ETHNOPHARMACOLOGICAL RELEVANCE: Uncaria tomentosa (Willd. Ex Schult) DC is used by indigenous tribes in the Amazonian region of Central and South America to treat inflammation, allergies and asthma. The therapeutic properties of U. tomentosa have been attributed to the presence of tetracyclic and pentacyclic oxindole alkaloids and to phenolic acids. AIMS OF THE STUDY: To characterize aqueous bark extracts (ABE) and aqueous leaf extracts (ALE) of U. tomentosa and to compare their anti-inflammatory effects...
February 9, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29432855/suppression-of-lung-inflammation-by-the-methanol-extract-of-spilanthes-acmella-murray-is-related-to-differential-regulation-of-nf-%C3%AE%C2%BAb-and-nrf2
#16
Kyun Ha Kim, Eun Jung Kim, Min Jung Kwun, Ji Yeon Lee, Tran The Bach, Sang Mi Eum, Jun Yong Choi, Sayeon Cho, Sang-Jun Kim, Seung-Il Jeong, Myungsoo Joo
ETHNOPHARMACOLOGICAL RELEVANCE: Although Spilanthes acmella has been used to relieve inflammation, fever, pain, or infection in traditional Asian medicine, experimental evidence supporting these functions is scarce. Here, we examined an anti-inflammatory function and a possible underlying mechanism of S. acmella Murray (SAM). MATERIALS AND METHOD: The methanol extract of SAM was fingerprinted by HPLC. C57BL/6 mice were administered with a single intratracheal (i...
February 9, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29428242/bu-shen-yi-sui-capsule-promotes-remyelination-correlating-with-sema3a-nrp-1-lif-lifr-and-nkx6-2-in-mice-with-experimental-autoimmune-encephalomyelitis
#17
Pei-Yuan Zhao, Yong-Qiang Wang, Xi-Hong Liu, Ying-Jun Zhu, Hui Zhao, Qiu-Xia Zhang, Fang Qi, Jun-Ling Li, Nan Zhang, Yong-Ping Fan, Kang-Ning Li, Yuan-Yuan Zhao, Jian-Feng Lei, Lei Wang
ETHNOPHARMACOLOGICAL RELEVANCE: Bu Shen Yi Sui capsule (BSYSC), based on traditional Chinese formula Liu Wei Di Huang pill, is effective for the treatment of multiple sclerosis (MS) in clinical experience and trials. Our previous studies confirmed that BSYSC had the neuroprotective effect in MS and its animal model, experimental autoimmune encephalomyelitis (EAE); however, its mechanism of action was not clear. Thus, the effect of BSYSC on remyelination and the underlying mechanisms were investigated in the EAE mice...
February 8, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29428241/ethnomedical-uses-and-pharmacological-activities-of-most-prevalent-species-of-genus-piper-in-panama-a-review
#18
REVIEW
Armando A Durant-Archibold, Ana I Santana, Mahabir P Gupta
ETHNOPHARMACOGICAL RELEVANCE: Piperaceae is the fifth largest family of plants in Panama. This review focuses on the ethnomedical uses of the most prevalent Panamanian species and biological activities of their extracts and/or constituents both in Panama and worldwide. Many species have a plethora of ethnomedical uses such as antibacterial, antifungal, anti-inflammatory, anticancer, antidiabetic, anti-Helicobacter pylori, antiulcer, antiprotozoal, estrogenic, insecticidal, local anesthetic, diuretic, and for women's health conditions...
February 8, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29428240/anti-inflammatory-activity-and-gastroprotective-effect-of-hertia-cheirifolia-l-roots-extract
#19
Kaouther Majouli, Assia Hamdi, Amal Abdelhamid, Abderrahman Bouraoui, Adberraouf Kenani
ETHNOPHARMACOLOGICAL RELEVANCE: Hertia cheirifolia L. is used traditionally to treat rheumatic pains and known as a medicinal plant having several pharmaceutical and biological activities. The present study evaluated in vivo the anti-inflammatory and gastroprotective effects of the methanolic extract from H. cheirifolia L. MATERIALS AND METHODS: Reverse phase high-performance liquid chromatography (RP-HPLC) was performed to identify various chemical components of the plant extract...
February 8, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29427634/mucuna-pruriens-l-dc-chemo-sensitize-human-breast-cancer-cells-via-downregulation-of-prolactin-mediated-jak2-stat5a-signaling
#20
Sonam Sinha, Sonal Sharma, Jaykant Vora, Heta Shah, Anshu Srivastava, Neeta Shrivastava
ETHNOPHARMACOLOGICAL RELEVANCE: Mucuna pruriens (L.) DC (MP) is an ancient Indian medicinal plant traditionally used to treat Parkinson's disease. L-Dopa (LD), precursor of dopamine is abundantly found in the seeds of MP. L-dopa is a natural inhibitor of prolactin (PRL) hormone which is required to maintain lactation in women but it's over production (hyperprolactinemia) plays critical role in advancement of breast cancer. AIM OF THE STUDY: We aim to examine the pharmacological effect of LD and MP on this hyperprolactinemia associated breast cancer and related signaling for effective management of the disease...
February 7, 2018: Journal of Ethnopharmacology
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