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Journal of Ethnopharmacology

Ju-Yeon Park, Sun-Dong Park, Young Jun Koh, Dong-Il Kim, Ju-Hee Lee
ETHNOPHARMACOLOGICAL RELEVANCE: Dipsaci Radix, which is the dried root of Dipsacus asperoides C. Y. Cheng and T. M. Ai (Dipsacaceae), is used to treat back pain and blood stasis syndrome in Korean traditional medicine. AIM OF THE STUDY: To understand the mechanisms responsible for the pharmacological activities of D. asperoides, we investigated the inhibitory effect of D. asperoides on lipopolysaccharide (LPS)-induced inflammation in mouse macrophages RAW 264.7 cells...
November 8, 2018: Journal of Ethnopharmacology
O S Ajayi, M A Aderogba, E M Obuotor, R R T Majinda
BACKGROUND: Anthocleista vogelii (Planch) is used in folk medicine in conditions related to inflammation and oxidative stress. AIM OF STUDY: The leaf extracts were investigated for their bioactive constituents in our quest for novel compounds for the management of neurodegenerative diseases. MATERIALS AND METHODS: Anthocleista vogelii crude leaf extract obtained from 80% methanol was successively partitioned with n-hexane, dichloromethane (DCM), ethyl acetate (EtOAc) and n-butanol...
November 8, 2018: Journal of Ethnopharmacology
Guilherme Vieira Botelho de Almeida, Karuppusamy Arunachalam, Sikiru Olaitan Balogun, Eduarda Pavan, Sérgio Donizeti Ascêncio, Ilsamar Mendes Soares, Ana C Zanatta, Wagner Vilegas, Antonio Macho, Domingos Tabajara de Oliveira Martins
ETHNOPHARMACOLOGICAL RELEVANCE: Virola elongata is a tree species belonging to the Myristicaceae family, distributed in the North and Midwest regions of Brazil, in the phytogeographic domain of the Amazon. The aqueous infusion or the hydroethanolic macerate of the stem bark of V. elongata are used in Brazilian and Ecuadorian indigenous folk medicine for several ethnopharmacological purposes, principally, in the treatment of stomach pain, indigestions, and gastric ulcers. This study was aimed to investigate the gastroprotective activity of this plant in order to support its popular use with scientific evidence...
November 8, 2018: Journal of Ethnopharmacology
Seong-Gu Jeong, Sunggyu Kim, Han Gyung Kim, Eunji Kim, Deok Jeong, Ji Hye Kim, Woo Seok Yang, Junsang Oh, Gi-Ho Sung, Mohammad Amjad Hossain, Jongsung Lee, Jong-Hoon Kim, Jae Youl Cho
ETHNOPHARMACOLOGICAL RELEVANCE: Mycetia cauliflora Reinw. (Rubiaceae) has been used as a traditional remedy to ameliorate clinical signs of inflammatory diseases, including pain, inflammation, ulcers, and wounds. Among the Mycetia subfamilies, the molecular and cellular mechanisms of Mycetia longifolia (Rubiaceae) have been studied. However, those of Mycetia cauliflora are not clearly understood. Comprehensive investigation of this plant is necessary to evaluate its potential for ethnopharmacological use...
November 8, 2018: Journal of Ethnopharmacology
Tingting Fang, Yuan Fang, Xiaojing Xu, Mingyan He, Zhiying Zhao, Peixin Huang, Feifei Yuan, Mengzhou Guo, Biwei Yang, Jinglin Xia
ETHNO-PHARMACOLOGICAL RELEVANCE: Numerous studies have demonstrated the potent anticancer activity of various Chinese herbs. Actinidia Chinensis Planch root (acRoots), a traditional Chinese medicine, functions as an antitumor and detoxifying agent and plays a role in diuresis and hemostasis. Treatment with acRoots confers strong inhibition of tumor growth in various forms of cancer. Here, we evaluated the anticancer activity and molecular mechanisms of Actinidia Chinensis Planch root extract (acRoots) on hepatocellular carcinoma (HCC)...
November 8, 2018: Journal of Ethnopharmacology
C S P Della Pasqua, R D Iwamoto, E Antunes, A A Borghi, A C F H Sawaya, E C T Landucci
ETHNOPHARMACOLOGICAL RELEVANCE: Mikania glomerata Spreng. (MG) and Mikania laevigata Sch. Bip. ex Baker (ML), popularly known as guaco, are medicinal plants similar in morphology, chemical composition and medicinal uses. Both species are often used and sold without distinction; however, it is believed that their chemical composition is different. AIM: Thus, the aim of this study is to investigate if the aqueous extract of MG and ML present similar anti-inflammatory activity to the point of being used interchangeably...
November 8, 2018: Journal of Ethnopharmacology
María Eugenia Suárez
ETHNOPHARMACOLOGICAL RELEVANCE: This article presents the results of a study on wild plant pharmacopeia and medical ethnobotany of the Wichí people of the South American Gran Chaco region, where native forest still persist. Few previous works on the former subjects exist, with only partial information. Traditionally, shamans are in charge of healing serious diseases and wild plants are used for treating minor problems. Some ethnobotanists believe that much of the present pharmacopeia of native peoples of the Gran Chaco comes from the Criollos (local non-native people) and that medicinal plants and uses would have been much fewer in the past...
November 7, 2018: Journal of Ethnopharmacology
Sergio Ortiz, Marylin Lecsö-Bornet, Christine Bonnal, Sandrine Houze, Sylvie Michel, Raphaël Grougnet, Sabrina Boutefnouchet
ETHNOPHARMACOLOGICAL RELEVANCE: Previous ethnobotanical surveys from the north Andean part of Chile, where different ethnic groups are co-existing, with the preeminence of Aymara and Atacama traditions, revealed an extensive domestic use of the local flora. In these communities, traditional medicinal uses are mainly related to the treatment of respiratory, gastro-intestinal and urinary disorders, pain and inflammation, which is closely linked to epidemiological observations. AIM OF THE STUDY: As these symptoms may be related to infectious diseases, a bioguided evaluation of antibacterial and antifungal activity was conducted on eighteen species selected with the Taira community, in Ollague...
November 6, 2018: Journal of Ethnopharmacology
Changyoung Lee, Soo-Yong Kim, Sangmi Eum, Jin-Hyub Paik, Tran The Bach, Ashwini M Darshetkar, Ritesh Kumar Choudhary, Do Van Hai, Bui Hong Quang, Nguyen Trung Thanh, Sangho Choi
ETHNOPHARMACOLOGICAL RELEVANCE: The ethnobotanical survey was carried out in the Bac Huong Hoa Nature Reserve (BHHNR), Vietnam. The Van Kieu ethnic group, the inhabitant of Nature Reserve, is rich in knowledge about the medicinal plants found in the Nature Reserve. However, their knowledge is less documented. AIM OF THE STUDY: The present study was conducted to document the use of medicinal plants, plant parts used, mode of preparation and delivery by the ethnic group of Van Kieu...
November 6, 2018: Journal of Ethnopharmacology
Chao Wu, Weiyang Chen, Meng Fang, Alex Boye, Xiangming Tao, Yuanyuan Xu, Shu Hou, Yan Yang
ETHNOPHARMACOLOGICAL RELEVANCE: Compound Astragalus and Salvia miltiorrhiza extract (CASE), containing astragalosides, astragalus polysaccharide extracted from Astragalus membranaceus (Fisch.) Bge. and salvianolic acids from Salvia miltiorhiza Bge., has been found to inhibit hepatocarcinogenesis via mediating transforming growth factor-β (TGF-β)/Smad signaling, especially Smad3 phosphorylation. The crucial interaction between microRNA-145/microRNA-21 (miR-145/miR-21) and Smad3 phosphorylation is implicated in the pathogenesis and progression of hepatocellular carcinoma (HCC)...
November 6, 2018: Journal of Ethnopharmacology
Tanvi H Desai, Shrikant V Joshi
ETHNOPHARMACOLOGICAL RELEVANCE: Albizia lebbeck (L.) Benth. (Family: Mimosaceae) is commonly known as Sirisha in Sanskrit. The leaves and pods of A. lebbeck were claimed to be used against cancer in traditional medicine. Previous studies using bark, leaves, seeds and pods of A. lebbeck showed cytotoxic activity against hepatic, colon, larynx, cervical and breast cancer cell lines. AIM OF THE STUDY: To evaluate the anticancer activity of saponin rich fraction of Albizia lebbeck by using various in vitro models...
November 5, 2018: Journal of Ethnopharmacology
Jiahua Ma, Jun Huang, Shiyao Hua, Yan Zhang, Yiwei Zhang, Tingting Li, Lin Dong, Qinghan Gao, Xueyan Fu
ETHNOPHARMACOLOGICAL RELEVANCE: Angelica biserrata (R.H.Shan & C.Q.Yuan) C.Q.Yuan & R.H.Shan (Angelica pubescens Maxim. f. biserrata Shan et Yuan) (A.biserrata) is a widely used traditional Chinese medicine; its roots known as 'Duhuo' in China. The herb is used for expelling wind, eliminating dampness, and terminating pain. Moreover, it is used for treating the onset of anemofrigid-damp arthralgia, pain of the waist and knee and headache caused by latent wind pathogenic factor or damp-cold pathogenic factor...
November 5, 2018: Journal of Ethnopharmacology
Wonjong Lee, Eun-Rhan Woo, Dong Gun Lee
ETHNOPHARMACOLOGICAL RELEVANCE: Aster yomena, a perennial herb that grows mainly in South Korea, has been employed in the traditional temple food for antibiotic efficacy. Recently, it was reported that apigenin isolated from A. yomena has a physical antifungal mechanism targeting membrane against Candida albicans. AIM OF THE STUDY: Our study aimed to investigate the biochemical responses underlying the antifungal activity of apigenin isolated from A. yomena due to lack studies reporting the investigation of intracellular responses of apigenin in C...
November 5, 2018: Journal of Ethnopharmacology
Muhammet Emin Cam, Ayse Nur Hazar-Yavuz, Sila Yıldız, Busra Ertas, Betul Ayaz Adakul, Turgut Taskın, Saadet Alan, Levent Kabasakal
ETHNOPHARMACOLOGICAL RELEVANCE: Thymus praecox subsp. skorpilii var. skorpilii (syn. Thymus praecox subsp. jankae (Celak.) Jalas) is consumed as a Turkish folk medicine for the treatment of spasm, sore throat and shortness of breath, also having strong antioxidant activity and the leaves of the plant have been utilized for the treatment of diabetes as the decoction in Turkey. AIM OF THE STUDY: In the present study, we aimed to investigate the potential mechanism of antidiabetic action of Thymus praecox subsp...
November 3, 2018: Journal of Ethnopharmacology
Vera Lúcia de Almeida, Cláudia Gontijo Silva, Andréia Fonseca Silva, Priscilla Rodrigues Valadares Campana, Kenn Foubert, Júlio César Dias Lopes, Luc Pieters
ETHNOPHARMACOLOGICAL RELEVANCE: Species of Aspidosperma are known popularly as "peroba, guatambu, carapanaúba, pau-pereiro" and "quina". The genus can be found in the Americas, mainly between Mexico and Argentina. Many species of Aspidosperma are used by the population in treating cardiovascular diseases, malaria, fever, diabetes and rheumatism. The phytochemical aspects of the species of the genus Aspidosperma have been studied extensively. The monoterpene indole alkaloids are the main secondary metabolites in Aspidosperma species, and about 250 of them have been isolated showing a considerable structural diversity...
November 2, 2018: Journal of Ethnopharmacology
Jang Mi Han, Eun Kyeong Lee, So Youn Gong, Jae Kyung Sohng, Yue Jai Kang, Hye Jin Jung
ETHNOPHARMACOLOGY RELEVANCE: Sparassis crispa, also known as cauliflower mushroom, has been used historically in traditional Asian medicine. It possesses various biological activities, such as immunopotentiation, anti-diabetes, anti-cancer, and anti-inflammatory effects. Recently, we isolated the non-aqueous fraction from methanol extract of S. crispa (SCF4) by using water-organic solvent mixtures and high-performance liquid chromatography (HPLC). In the present study, we identified the anti-inflammatory activity and action mechanism of SCF4 in lipopolysaccharide (LPS)-stimulated RAW264...
November 2, 2018: Journal of Ethnopharmacology
Frederico Formagio-Neto, Carla Roberta Ferreira Volobuff, Milena Menezes Corrêa Pederiva, Zefa Valdevina Pereira, Maria Helena Sarragiotto, Claudia Andrea Lima Cardoso, Candida Aparecida Leite Kassuya, Anelise Samara Nazari Formagio
ETHNOPHARMACOLOGICAL RELEVANCE: Alchornea glandulosa (Euphorbiaceae) has traditionally been used in medicine for treating immune-mediated inflammatory diseases. AIM OF STUDY: This work aimed to evaluate the anti-inflammatory effects of a methanolic extract of leaves from A. glandulosa (MEAG), as well as the ethyl acetate fraction (EAFAG) and isolated compound guanidine alkaloid N-1, N-2, N-3-triisopentenylguanidine (AG-1), in experimental in vivo models of inflammation in mice...
November 2, 2018: Journal of Ethnopharmacology
Muhammad Ibrar, Mir Azam Khan, Abdullah, Mohammad Nisar, Munasib Khan
ETHNOPHARMACOLOGICAL RELEVANCE: Paeonia emodi Wall. ex Royle (peony) is an important member of family Paeoniaceae. Different parts of the plant have been folklorically used for treatment of different diseases. Infusion of dried flowers is used to treat diarrhea, the seeds are emetic and cathartic while the rhizome has been indicated for the treatment of hysteria, abdominal spasm, nervine tonic and headache. Besides these, peony has also been used in different respiratory and cardiovascular diseases (CVDs) like hypertension, palpitations, congestive heart failure and atherosclerosis...
November 1, 2018: Journal of Ethnopharmacology
Róża Sawczuk, Joanna Karpinska, Wojciech Miltyk
ETNOPHARMACOLOGICAL RELEVANCE: Bee products have been used in natural medicine for centuries. The largest number of scientific reports focused on the properties and therapeutic action of propolis, royal jelly, honey, bee venom and pollen. Less information can be foundabout another product of beekeeping which is drone brood. Drone brood - form of bee larvae, from which drones will develop- is considered to be waste of beekeepers. Drones are responsible for the fertilization of aqueen bee, thereby prolonging bee species...
November 1, 2018: Journal of Ethnopharmacology
Li-Feng Chen, Yuan-Lin Zhong, Ding Luo, Zhong Liu, Wei Tang, Wen Cheng, Si Xiong, Yao-Lan Li, Man-Mei Li
ETHNOPHARMACOLOGICAL RELEVANCE: Lophatherum gracile, an important medicinal plant, is used traditionally in the treatment of cough associated with lung heat and inflammation. In this study, an ethanol extract of L. gracile (DZY) was shown to inhibit respiratory syncytial virus (RSV) infection and RSV-induced inflammation in vitro and in vivo. These findings provide a strong and powerful support for the traditional use of L. gracile in the treatment of RSV-related diseases. AIM OF THE STUDY: To determine the anti-RSV activities of DZY and its ingredients, and explore the relationship between RSV infection and inflammation...
October 31, 2018: Journal of Ethnopharmacology
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