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Acta Medica Indonesiana

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https://www.readbyqxmd.com/read/29093241/national-consensus-on-management-of-dyspepsia-and-helicobacter-pylori-infection
#1
Ari F Syam, Marcellus Simadibrata, Dadang Makmun, Murdani Abdullah, Achmad Fauzi, Kaka Renaldi, Hasan Maulahela, Amanda P Utari
Dyspepsia is one of numerous general complaints, which is commonly encountered by doctors of various disciplines. In daily practice, the complaint is not only limited for gastroenterologists. Knowledge on pathophysiology of dyspepsia have been developing continuously since a scientific investigation has been started in 1980's, which considers Helicobacter pylori as one of key factor in managing dyspepsia, either it is associated with ulcer or non-ulcer. The management of dyspepsia cannot be separated from the management of H...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093240/current-issues-of-gastroenterology-in-indonesia
#2
Marcellus Simadibrata, Randy Adiwinata
Indonesia is one of the most populous developing countries in the world. Similar with other developing countries, Indonesia has been suffered from the high incidence of gastroenterology diseases that mainly due to infection. In the recent years, Indonesia had also increased number of non-infectious gastroenterology diseases cases such as inflammatory bowel disease, gastroesophageal reflux disease, and colorectal cancer. Nevertheless, the developments of diagnostic and therapeutic modality along with the cooperation between sectors have undergone rapid progress as an effort in improving digestive health in Indonesia...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093239/paraneoplastic-arthritis-in-a-patient-with-non-hodgkin-s-lymphoma
#3
Guntur Darmawan, Indra Wijaya, Laniyati Hamijoyo, Trinugroho Heri Fadjari
Paraneoplastic syndromes are a group of disorders associated with benign or malignant tumors but not related to mass effect or invasion directly. Paraneoplastic syndromes may affect any organic system of the human body, such as endocrine, neurologic, dermatologic, hematologic, rheumatologic. Paraneoplastic rheumatic syndromes are not quite common, about 7-10% of paraneoplastic syndromes, and may mimic rheumatic diseases. We present an interesting case of paraneoplastic arthritis in a woman with non-Hodgkin's lymphoma...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093238/multidiscipline-care-for-type-2-diabetes-patients-from-general-to-asian-population
#4
Benedicta Mutiara Suwita, Dewi Friska, Deriyan Sukma Widjaja, Liana Srisawitri
Multidiscipline care is defined as a care consisting of at least a physician, a nurse, and other healthcare worker (eg. dietician). Multidiscipline care has generated benefits, both in medical aspects (eg. increasing patients' compliance) and nonmedical aspects (eg. more cost-effective than conventional treatment). There are several models of multidiscpline care; however, which model is more suitable for type 2 diabetes care is not clear yet. In this review, we aimed to identify and compare multidiscipline care method for reducing glycated hemoglobin ( HbA1C) levels in type 2 diabetes patients, particularly Asian patients because they have greater tendency to develop type 2 diabetes at lower degrees of obesity and at younger ages than Caucasian ethnic group...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093237/basal-cell-carcinoma-of-vermilion-mucosa-of-upper-lip-a-rare-case-report
#5
Reza Yaghoobi, Nastaran Ranjbari, Nader Pazyar, Maryam Foroozan, Amir Feily
Although basal cell carcinoma (BCC) is a common skin tumor, very rare cases of BCC arising from upper vermilion mucosa of lip have been reported previously. This tumor basically, originates from pillar structures and the involvement of the vermilion lip contrasts this concept so it is devoid of hair follicles and sweat glands. The exact pathogenesis of vermilion lip BCC is not clear but it has been postulated that the neoplasm originates from the pluripotential epithelial cells of the oral mucosa and epidermis...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093236/primary-hyperaldosteronism-due-to-adrenocortical-adenoma-a-case-report
#6
Tjokorda Gde Dalem Pemayun, Ridho Naibaho, Maretina W Wiyati, Ardy Santosa, Siti Amarwati
Primary hyperaldosteronism is an adrenal abnormality in which there is some degree of autonomy of aldosterone secretion. We report a case of thirty three years old Javanese female presented with uncontrolled hypertension, muscular weakness, cramps  and progressing shortness of breath during working for 6 years. She had history of hypertension since age 20. Her serum potassium level was always low that associated with inappropriate kaliuresis. Blood gas analysis revealed metabolic alkalosis. Sonography of the adrenal gland showed right hipoechoic architecture; CT scan of the abdomen confirmed an right adrenal tumor measured 4 cm in its greatest dimension...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093235/pollen-serum-specific-ige-sensitization-in-respiratory-allergic-patients-in-jakarta-indonesia
#7
Iris Rengganis, Agus Joko Susanto
BACKGROUND: pollens from trees or grasses in Indonesia have a perennial distribution due to the tropical climate. However, pollen allergy has not been well studied. This study aimed to evaluate the profile of pollen IgE sensitization in respiratory allergic patients in Jakarta. METHODS: this was a cross-sectional study in patients with a history of respiratory allergy in Jakarta, Indonesia between September and December 2016. Adult asthmatic patients aged 19-60 years were invited to undergo serum specific IgE testing at the Allergy and Immunology Clinic, Cipto Mangunkusumo Hospital, Jakarta...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093234/comparative-cost-analysis-of-four-interventions-to-prevent-hiv-transmission-in-bandung-indonesia
#8
Eveline J M Verstraaten, Fenna M M Beeren, Jip L C Janssen, Sophie Kemper, Adiatma Y M Siregar, Noor Tromp, Rob Baltussen
BACKGROUND: the costs of HIV/AIDS interventions in Indonesia are largely unknown. Knowing these costs is an important input for policy makers in the decision-making of setting priorities among HIV/AIDS interventions. The aim of this analysis is to determine the costs of four HIV/AIDS interventions in Bandung, Indonesia in 2015, to inform the local AIDS commission. METHODS: data on utilization and costs of the different interventions were collected in a sexual transmitted infections (STI)-clinic and the KPA, the local HIV/AIDS commission, for the period of January 2015-December 2015...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093233/optimal-amikacin-levels-for-patients-with-sepsis-in-intensive-care-unit-of-cipto-mangunkusumo-hospital-jakarta-indonesia
#9
Gestina Aliska, Rianto Setiabudy, Purwantyastuti Purwantyastuti, Anis Karuniawati, Rudyanto Sedono, Trisni U Dewi, Muhammad K Azwar
BACKGROUND: Amikacin is one of the antibiotics of choice for sepsis and septic shock. Pharmacokinetic of amikacin can be influenced by septic condition with subsequent effect on its pharmacodynamic. At Cipto Mangunkusumo Hospital (RSCM), Jakarta, adult patients in the ICU were given standard amikacin dose of 1 g/day, however the achievement of optimal plasma level had never been evaluated. This study aimed to evaluate whether the optimal plasma level of amikacin was achieved with the use of standard dose in septic conditions...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093232/treatment-response-monitoring-of-chronic-hepatitis-b-patients-using-transient-elastography-and-aspartate-aminotransferase-to-platelet-ratio-index-apri
#10
Ignatius R Tenggara, C Rinaldi Lesmana, Rino A Gani
BACKGROUND: Hepatitis B is endemic in Indonesia and treatment response need to be monitored during and after antiviral therapy. Liver stiffness measurement and alanine aminotransferase-to-platelet ratio index (APRI) are noninvasive method to detect liver fibrosis available in Indonesia. However, little is known about their ability to evaluate treatment response in chronic hepatitis B (CHB) patients in Indonesia. This study aimed to investigate liver stiffness changes by transient elastography (TE) and APRI before and after one-year oral antiviral treatment in CHB patients and the correlation between TE and APRI...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093231/factors-related-with-handgrip-strength-in-elderly-patients
#11
Nur Riviati, Siti Setiati, Purwita W Laksmi, Murdani Abdullah
BACKGROUND: the aging process causes decreasing in the function of various organs. Skletal muscle is one of the organs affected by aging process. It is known as sarcopenia. Sarcopenia is defined as a syndrome characterized by progressive loss of muscle mass and strength. The handgrip strength examination is often applied as a sarcopenia filtering technique. This study aimed to determine the relationship between age, nutritional status, and chronic diseases such as stroke, hypertension (HT), diabetes mellitus (DM), coronary heart disease (CHD), and chronic obstructive pulmonary disease (COPD) with handgrip strength...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093230/sero-and-molecular-epidemiology-of-hiv-1-in-papua-province-indonesia
#12
Muhammad Qushai Yunifiar, Tomohiro Kotaki, Adiana Mutamsari Witaningrum, Siti Qamariyah Khairunisa, Dwi Wahyu Indriati, Meilani Meilani, Tigor Yeheskiel, Shuhei Ueda, Nasronudin Nasronudin, Masanori Kameoka
BACKGROUND: human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) cause serious health problems and affect the Indonesian economy. Papua province has the highest prevalence of HIV infection in the country; however, epidemiological data are limited. Therefore, in order to reveal the current situation of HIV/AIDS in Papua province, sero- and molecular epidemiological studies of HIV were conducted. METHODS: serological tests were conducted on 157 healthy individuals from the general population residing in Paniai, Papua...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093229/the-role-of-cytotoxic-t-lymphocyte-associated-protein-4-ctla-4-gene-thyroid-stimulating-hormone-receptor-tshr-gene-and-regulatory-t-cells-as-risk-factors-for-relapse-in-patients-with-graves-disease
#13
Fatimah Eliana, Pradana Suwondo, Asmarinah Asmarinah, Alida Harahap, Samsuridjal Djauzi, Joedo Prihartono, Tjokorda Gde Dalem Pemayun
BACKGROUND: graves' disease (GD) is the most common condition of thyrotoxicosis. The management of GD is initiated with the administration of antithyroid drugs; however, it requires a long time to achieve remission. In reality more than 50% of patients who had remission may be at risk for relapse after the drug is stopped. This study aimed to evaluate the role of clinical factors such as smoking habit, degree of ophtalmopathy, degree of thyroid enlargement; genetic factors such as CTLA-4 gene on nucleotide 49 at codon 17 of exon 1, CTLA-4 gene of promotor -318, TSHR gene polymorphism rs2268458 of intron 1; and immunological factors such as regulatory T cells (Treg) and thyroid receptor antibody (TRAb); that affecting the relapse of patients with Graves' disease in Indonesia...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29093228/hiv-infection-in-indonesia
#14
Erni Juwita Nelwan
No abstract text is available yet for this article.
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28790235/the-challenge-in-diagnosis-and-current-treatment-of-chronic-thromboembolic-pulmonary-hypertension
#15
Anggoro Budi Hartopo, Lucida Kris Dinarti, Abdul S Wahab
Chronic thromboembolic pulmonary hypertension (CTEPH) is currently underdiagnosis and consequently undertreatment in the clinical practice. A deficient in diagnostic modality and treatment availability especially in developing countries makes the CTEPH diagnosis unlikely to confirm. However, high index of clinical suspicion of CTEPH will lead to proper diagnosis and correct treatment  with significant reduction in morbidity and mortality. Left untreated, the mean survival time is 6.8 years and the three year mortality rate may be as high as 90 %...
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28790234/fixed-dose-combination-antituberculosis-therapy-as-a-risk-factor-for-tuberculosis-recurrence-an-evidence-based-case-report
#16
Arvin Pramudita, Cleopas M Rumende, Ardi Findyartini
BACKGROUND: a patient with a history of tuberculosis (TB) has a risk up to 27% to develop recurrence within 2 years after being cured. Indonesia itself has more than 7,500 recurrent cases annually, regardless of reinfection or relapse. This is an important problem, as recurrent TB is associated with lower cure rates with the anti-TB therapy and higher risk of developing drug resistance. Some risk factors for this recurrence are smoking, poor treatment adherence, low economic status, and weak immune status...
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28790233/functional-dyspepsia-with-helicobacter-pylori-infection
#17
Rabbinu Rangga Pribadi, Ari Fahrial Syam, Ening Krisnuhoni
Helicobacter pylori infection is commonly found worldwide. In Indonesia, the prevalence of H. pylori infection is 22.1%. The bacteria are responsible for gastritis, peptic ulcer disease (PUD), and gastric cancer.Helicobacter pylori may also has a role in functional dyspepsia. Diagnostic approach consists of noninvasive and invasive examinations. One of the invasive strategy is upper gastrointestinal (UGI) endoscopy and gastric mucosa biopsy.
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28790232/corneal-sensitivity-as-a-potential-marker-of-diabetic-neuropathy
#18
Ratna Sitompul
Diabetes mellitus (DM) is a complex and chronic metabolic disorder leading to many complications. One of the most common complications of DM is diabetic neuropathy. There are many studies exploring corneal sensitivity as a potential marker of diabetic neuropathy. This review aims to explore association between corneal sensitivity and diabetic neuropathy. In diabetic neuropathy, corneal sensitivity is impaired due to low level of corneal nerve trophic factors, impaired sensory nerve fibers, and lost communication of dendtritic cell...
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28790231/inflammation-immunity-and-hypertension
#19
Arisya Agita, M Thaha Alsagaff
The immune system, inflammation and hypertension are related to each other. Innate and adaptive immunity system triggers an inflammatory process, in which blood pressure may increase, stimulating organ damage. Cells in innate immune system produce ROS, such as superoxide and hydrogen peroxide, which aimed at killing pathogens. Long-term inflammation process increases ROS production, causing oxidative stress which leads to endothelial dysfunction. Endothelial function is to regulate blood vessel tone and structure...
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28790230/ventilator-associated-pneumonia-vap-in-a-patient-with-guillain-barre-syndrome
#20
Anti Dharmayanti, Dalima Astrawinata
A 46-year-old man was admitted to ICU with a diagnosis at the time of admission of Guillain Barre Syndrome (GBS) and sepsis due to suspected Ventilator-Associated Pneumoniae (VAP). Specimens for the following laboratory workup were inquired, i.e. complete blood count, culture and resistance workup using specimens obtained from the tip of suction pipe, urinalysis and urine culture, blood culture and resistance, procalcitonin and lactate levels. Neutrophilia was found along with increased procalcitonin and lactate levels, which supported the sepsis diagnosis...
April 2017: Acta Medica Indonesiana
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