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Acta Medica Indonesiana

Audrey Amelia, Agung Nugroho, Paul N Harijanto
Bacterial resistance to antibiotics is a serious problem worldwide that affect the increment of morbidity and mortality rate; Enterobacteriaceae producing ESBL is one of the causes. However, there are still limited information regarding diagnosis and management of ESBL-E infection. Detection of ESBL-E requires certain steps that are problematic and time consuming. Diagnosis and management of ESBL-E infection have become more and more challenging due to limited diagnostic method available and choice of antibiotics that may be used, along with growing subtyped of ESBL through various of mutations...
April 2016: Acta Medica Indonesiana
Felix F Widjaja, Paramita Khairan, Telly Kamelia, Irsan Hasan
Large volume paracentesis may cause paracentesis induced circulatory dysfunction (PICD). Albumin is recommended to prevent this abnormality. Meanwhile, the price of albumin is too expensive and there should be another alternative that may prevent PICD. This report aimed to compare albumin to colloids in preventing PICD. Search strategy was done using PubMed, Scopus, Proquest, dan Academic Health Complete from EBSCO with keywords of "ascites", "albumin", "colloid", "dextran", "hydroxyethyl starch", "gelatin", and "paracentesis induced circulatory dysfunction"...
April 2016: Acta Medica Indonesiana
Dante S Harbuwono, Laurentius A Pramono, Hari Hendarto, Imam Subekti
This is a case of 51 year-old woman with uncontrolled type 2 diabetes mellitus which was diagnosed 1.5 year earlier, obesity with body mass index 32.2 kg/m2, waist circumference of 113 cm, diffuse goiter with neck circumference 40 cm, and hypertension with blood pressure >140/90 mmHg. Since 6 months ago, she often seemed like having less concentration or daydreaming, chronic fatigue, depression, and low food intake. Her body weight had been increasing over time. Her hypothyroidism clinical scoring Billewicz and Zulewski criterias were 17 and 8 respectively, showing that she tended to experience hypothyroidism...
April 2016: Acta Medica Indonesiana
Noorwati Sutandyo
Cancer prevalence is increasing every year and now cancer is the third highest cause of death in developing countries. Effective anticancer treatment can prolong life and improve the patient's quality of life. Targeted therapy is a new therapeutic modality which targets specific molecules in the cancer cell and disrupts dysregulated signaling pathways involved in carcinogenesis. Since targeted therapy does not attack normal cells, its side effects are considered low compared to chemotherapy. More than 15 drugs have been approved for treatment in various human cancers...
April 2016: Acta Medica Indonesiana
Een Hendarsih, Trinugroho H Fadjari, Amaylia Oehadian
We present 2 patients who developed spontaneous pneumothorax (SP) following rapid regression of lymphoma and rhabdomyosarcoma with lung metastases. Case 1, a 43-year old man was admitted to our hospital with dyspnea 10 days before admission. He denied any recent trauma or previous treatment for lung tuberculosis. Three weeks prior to admission, he received first cycle of CHOP for non-Hodgkin's lymphoma stage II BE. Chest X-ray consistent with right pneumothorax. After treatment with chest tube drainage for about 1 month, the patient recovered and chemotherapy could be continued without further complications...
April 2016: Acta Medica Indonesiana
Hendra Koncoro, I Komang W D Putra, I Dewa N Wibawa
Macrocystic serous cystadenoma is an unusual and essentially benign pancreatic tumor. Herein, we report on a 40-year-old woman diagnosed with macrocystic serous cystadenoma who presented with obstructive jaundice. A cystic lesion in the head and body of the pancreas was revealed by abdominal computed tomography. Intraoperative pancreatic cyst aspiration ruled out mucinous cystic neoplasm which has a malignant potential. The pancreatic cyst fluid cytology was basophilic amorph materials concluded as benign cystic lesion...
April 2016: Acta Medica Indonesiana
Catarina Budyono, Siti Setiati, Dyah Purnamasari, Cleopas M Rumende
AIM: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. METHODS: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged 60 years old who sought treatment at outpatient clinic of Geriatry and Diabetes Division at Cipto Mangunkusumo Hospital between January and March 2016. Orthostatic hypotension was defined as a decrease in systolic blood pressure 20 mmHg and/or diastolic pressure 10 mmHg within 3 minutes after changing position from lying to standing...
April 2016: Acta Medica Indonesiana
Dwi R Helianthi, Christina Simadibrata, Adiningsih Srilestari, Edy R Wahyudi, Rudy Hidayat
AIM: to compare the effectiveness of active laser acupuncture with placebo on reducing pain intensity and improving functional outcome in geriatric patients with knee osteoarthritis (OA). METHODS: a double-blind randomized controlled trial was conducted in geriatrics with knee OA at Medical Acupuncture Outpatient Clinic, Integrated Geriatric Outpatient Clinic, Rheumatology Outpatient Clinic of Cipto Mangunkusumo Hospital, Jakarta, during May to October 2015. Sixty two patients with knee OA were randomly assigned into two groups: active laser acupuncture group or placebo laser acupuncture group...
April 2016: Acta Medica Indonesiana
Anggoro B Hartopo, Irsad A Arso, Budi Y Setianto
AIM: the impact of atherogenic index of plasma (AIP), calculated as logarithmic of triglyceride:HDL ratio (log10.[TG:HDL]), on major adverse cardiovascular events (MACE) during acute myocardial infarction (AMI) has not been fully accepted. This study aims to investigate the role of AIP in predicting major adverse cardiovascular events following AMI during intensive care in the hospital. METHODS: this was a prospective cohort study. We enrolled subjects with AMI hospitalized in intensive coronary care unit at Dr...
April 2016: Acta Medica Indonesiana
Rama Firmanto, Gampo A Irdam, Irfan Wahyudi
AIM: this meta-analysis study will evaluate the incidence of urethral stricture as a successfull parameter in the management of PFUI through early realignment, compared with delayed urethroplasty. Long-term complications such as erectile dysfunction and incontinence on both methods will also be evaluated. METHODS: online literature was sourced from Pubmed, Embase, Cochrane, and Google Scholar. The incidence of stricture was evaluated from the entire study group of ER and DU...
April 2016: Acta Medica Indonesiana
Rachmat Hamonangan, Ika P Wijaya, Siti Setiati, Kuntjoro Harimurti
AIM: to obtain the proportion of frailty and the incidence of 30-day major adverse cardiovascular events (MACE) as well as to review the impact of frailty on the prognosis of elderly patients with coronary heart disease who underwent elective PCI. METHODS: this is a prospective cohort study to assess the frailty of elderly patients with coronary artery disease that underwent elective PCI in Cipto Mangunkusumo Hospital using the frailty phenotype criteria. They were subsequently followed-up for 30 days to see whether there was any MACE developed...
April 2016: Acta Medica Indonesiana
Harrina E Rahardjo, Pande M W Tirtayasa, Andika Afriansyah, Dyandra Parikesit, Muhammad I Akbar
AIM: to evaluate the effect of a 3-day course antibiotic post-urodynamic study (UDS) to prevent urinary tract infection (UTI). METHODS: this was a randomized double blind clinical trial on the proportion of UTI in patients who received levofloxacin 500 mg once a day for 3 days after UDS compared to nontreated patients. The outcome of this study was the incidence of lower UTI in levofloxacin group and placebo group. Lower UTI was defined as patient with one or more clinical symptoms of lower UTI and one or more urinalysis parameter of UTI...
April 2016: Acta Medica Indonesiana
Esthika Dewiasty
Cardiovascular disesase has been identified as the most frequent cause of death, while frailty has been identified as one of geriatric giants characterized by decreased physiological reserves and increased vulnerability. Despite of aggressive treatment for cardiovascular diseases such as invasive methods,frail patients who undergo these procedures tend to experience undesirable effects compared to non frail patients. As the population of elderly patiens worldwide is growing larger, these issues lead to major health problems that we have to overcome...
April 2016: Acta Medica Indonesiana
Andi Kristanto, Randy Adiwinata, Silvia Suminto, Benny N Kurniawan, Finna Christianty, Robert Sinto
The body circardian rhythm affects blood pressure variability at day and night, therefore blood pressure at day and night might be different. Nocturnal hypertension is defined as increase of blood pressure >120/70mmHg at night, which is caused by disturbed circadian rhythm, and associated with higher cardiovascular and cerebrovascular events also mortality in hypertensive patients. Nocturnal hypertension and declining blood pressure pattern, can only be detected by continuous examination for 24 hours, also known as ambulatory blood pressure measurement (ABPM)...
January 2016: Acta Medica Indonesiana
Eric D Tenda, Abraham Yakub
AIM: to determine the effectiveness of endobronchial valve placement as treatment of emphysema compared to medical care. METHODS: literature searching regarding comparison of endobronchial valve and medical care as treatment of emphysema on PubMed database. The quality of the literatures found was appraised by using critical appraisal sheet from Center of Evidence-Based Medicine, University of Oxford. RESULTS: two randomized controlled trials (RCT) were obtained from literature searching...
January 2016: Acta Medica Indonesiana
Indra Wijaya
A 57 year old female came with the complaint of recurrent headache, often fatigue, and sometimes feel numbs and rigid in her extremities, no other symptom was noted. Her body weight is stable and she was in menopausal state. She had a history of partial thyroidectomy 20 years ago and continues thiamazole 2.5 mg with seldom regular consult to physician. From the physical examination, the patient had a scar from thyroid surgery and other organs were in the normal condition. From laboratory examination, there was slight normocytic normochromic anemia (Hb: 10...
January 2016: Acta Medica Indonesiana
Zulkifli Amin, Hilman Z Amin, Lukman Z Amin
Obstructive sleep apnea (OSA) is a sleep respiratory disorder characterized by recurrent episodes of complete or partial airway obstruction, resulting in apneas or hypopneas. OSA could contribute to atherosclerosis through direct and indirect mechanisms. Endothelial dysfunction, sympathetic stimulation, and proinflammatory cytokine modulation caused by OSA play significant role to an atherosclesrotic event. Other risk factors of atherosclerosis like hypertension and diabetes mellitus also associated with OSA...
January 2016: Acta Medica Indonesiana
Reza Yaghoobi, Arezou Bagherzade, Maryam Aliabdi, Parvin Kheradmand, Afshin Kazerouni, Amir Feily
A 52-year-old woman was admitted with a 3 weeks history of periorbital edema and lips swelling. She developed several subcutaneous firm erythematous papules and nodules on the face, scalp and two indurated plaques on the upper back and left forearm. These lesions grew rapidly. The patient had a positive history of epileptic seizures since childhood. General examination was normal. There was a mild pitting edema on her hands and feet. Laboratory data were within normal limits. Histopathological examination revealed a well circumscribed accumulation of mucin in the dermis...
January 2016: Acta Medica Indonesiana
Rabbinu R Pribadi, Gurmeet Singh, Cleopas M Rumende
Pneumothorax is the presence of air in the pleural space. Its management consists of noninvasive and invasive therapies and it is determined based on clinical manifestations, type and size of pneumothorax. We present a case of a patient with diagnosis of primary spontaneous pneumothorax treated with incentive spirometry (noninvasive therapy). A 20 year old man came to respirology clinic with chief complaint of shortness of breath. He was recently diagnosed with left pneumothorax based on previous chest X-ray in another health care facilities and was advised to undergo tube thoracostomy but he refused the procedure...
January 2016: Acta Medica Indonesiana
Muhadi, Sally A Nasution, Rudi Putranto, Kuntjoro Harimurti
AIM: to assess heart rate variability (HRV) measurements using pulse photoplethysmograph (PPG) in predicting major adverse cardiac event (MACE) in acute coronary syndrome (ACS) patients. METHODS: a prospective cohort study was conducted among hospitalized ACS patients. Heart rate variability as predictor was measured by PPG within 48 hours after admission and the incidence of MACE as outcome was identified during ICCU stay. The ability of HRV in predicting MACE during hospitalization was determined by area under ROC curve (AUC) of low frequency (LF), high fequency (HF), and LF/HF ratio parameters...
January 2016: Acta Medica Indonesiana
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