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Hearing Research

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https://www.readbyqxmd.com/read/28441570/neural-indices-of-phonemic-discrimination-and-sentence-level-speech-intelligibility-in-quiet-and-noise-a-p3-study
#1
Tess K Koerner, Yang Zhang, Peggy B Nelson, Boxiang Wang, Hui Zou
This study examined how speech babble noise differentially affected the auditory P3 responses and the associated neural oscillatory activities for consonant and vowel discrimination in relation to segmental- and sentence-level speech perception in noise. The data were collected from 16 normal-hearing participants in a double-oddball paradigm that contained a consonant (/ba/ to /da/) and vowel (/ba/ to /bu/) change in quiet and noise (speech-babble background at a -3 dB signal-to-noise ratio) conditions. Time-frequency analysis was applied to obtain inter-trial phase coherence (ITPC) and event-related spectral perturbation (ERSP) measures in delta, theta, and alpha frequency bands for the P3 response...
April 18, 2017: Hearing Research
https://www.readbyqxmd.com/read/28432874/delayed-changes-in-auditory-status-in-cochlear-implant-users-with-preserved-acoustic-hearing
#2
Rachel A Scheperle, Viral D Tejani, Julia K Omtvedt, Carolyn J Brown, Paul J Abbas, Marlan R Hansen, Bruce J Gantz, Jacob J Oleson, Marie V Ozanne
This retrospective review explores delayed-onset hearing loss in 85 individuals receiving cochlear implants designed to preserve acoustic hearing at the University of Iowa Hospitals and Clinics between 2001 and 2015. Repeated measures of unaided behavioral audiometric thresholds, electrode impedance, and electrically evoked compound action potential (ECAP) amplitude growth functions were used to characterize longitudinal changes in auditory status. Participants were grouped into two primary categories according to changes in unaided behavioral thresholds: (1) stable hearing or symmetrical hearing loss and (2) delayed loss of hearing in the implanted ear...
April 12, 2017: Hearing Research
https://www.readbyqxmd.com/read/28412580/a-non-toxic-dose-of-cobalt-chloride-blocks-hair-cells-of-the-zebrafish-lateral-line
#3
William J Stewart, Jacob L Johansen, James C Liao
Experiments on the flow-sensitive lateral line system of fishes have provided important insights into the function and sensory transduction of vertebrate hair cells. A common experimental approach has been to pharmacologically block lateral line hair cells and measure how behavior changes. Cobalt chloride (CoCl2) blocks the lateral line by inhibiting calcium movement through the membrane channels of hair cells, but high concentrations can be toxic, making it unclear whether changes in behavior are due to a blocked lateral line or poor health...
April 12, 2017: Hearing Research
https://www.readbyqxmd.com/read/28426992/factors-affecting-sound-energy-absorbance-in-acute-otitis-media-model-of-chinchilla
#4
Xiying Guan, Thomas W Seale, Rong Z Gan
Acute otitis media (AOM) is a rapid-onset infection of the middle ear which results in middle ear pressure (MEP), middle ear effusion (MEE), and structural changes in middle ear tissues. Previous studies from our laboratory have identified that MEP, MEE, and middle ear structural changes are three factors affecting tympanic membrane (TM) mobility and hearing levels (Guan et al., 2014, 2013). Sound energy reflectance or absorbance (EA) is a diagnostic tool increasingly used in clinical settings for the identification of middle ear diseases...
April 10, 2017: Hearing Research
https://www.readbyqxmd.com/read/28390777/on-the-role-of-ephrina2-in-auditory-function
#5
Neil J Ingham, Karen P Steel, Uwe Drescher
Recent findings suggest that the manipulation of the EphA/ephrinA system can improve hearing threshold sensitivity in the auditory system (Yates et al., 2014). These results appear to open-up the possibility that pharmacological manipulation of this system could lead to the development of treatments to cure some types of hearing loss. As a first step towards this goal, we have performed a further series of auditory brainstem evoked potential recordings on ephrinA2 homozygous knockout mice and their wildtype littermates in order to replicate the previously reported findings...
April 5, 2017: Hearing Research
https://www.readbyqxmd.com/read/28390736/reply-to-critical-examination-of-the-article-impulse-noise-injury-prediction-based-on-the-cochlear-energy
#6
LETTER
Brissi Zagadou, Philemon Chan, Kevin Ho, David Shelley
No abstract text is available yet for this article.
March 30, 2017: Hearing Research
https://www.readbyqxmd.com/read/28390253/the-intelligibility-of-speech-in-a-harmonic-masker-varying-in-fundamental-frequency-contour-broadband-temporal-envelope-and-spatial-location
#7
Thibaud Leclère, Mathieu Lavandier, Mickael L D Deroche
Differences in fundamental frequency (F0), modulations in the masker envelope, and differences in spatial location between a speech target and a masker can improve speech intelligibility in cocktail-party situations. These cues have been thoroughly investigated independently and associated with unmasking mechanisms: F0 segregation, temporal dip listening and spatial unmasking, respectively. Two experiments were conducted to examine whether F0 segregation interacts with spatial unmasking (experiment 1) or temporal modulations in the masker envelope (experiment 2) by measuring speech reception thresholds for a monotonized or an intonated voice against eight types of harmonic complex masker...
March 29, 2017: Hearing Research
https://www.readbyqxmd.com/read/28431309/brief-critical-examination-of-the-article-impulse-noise-injury-prediction-based-on-the-cochlear-energy-by-zagadou-chan-ho-and-shelly
#8
LETTER
G Richard Price, Joel T Kalb, Charles R Jokel
No abstract text is available yet for this article.
March 28, 2017: Hearing Research
https://www.readbyqxmd.com/read/28431308/hyperexcitability-of-inferior-colliculus-and-acoustic-startle-reflex-with-age-related-hearing-loss
#9
Binbin Xiong, Ana'am Alkharabsheh, Senthilvelan Manohar, Guang-Di Chen, Ning Yu, Xiaoming Zhao, Richard Salvi, Wei Sun
Chronic tinnitus and hyperacusis often develop with age-related hearing loss presumably due to aberrant neural activity in the central auditory system (CAS) induced by cochlear pathologies. However, the full spectrum of physiological changes that occur in the CAS as a result age-related hearing loss are still poorly understood. To address this issue, neurophysiological measures were obtained from the cochlea and the inferior colliculus (IC) of 2, 6 and 12 month old C57BL/6J mice, a mouse model for early age-related hearing loss...
March 27, 2017: Hearing Research
https://www.readbyqxmd.com/read/28323018/modulation-of-auditory-percepts-by-transcutaneous-electrical-stimulation
#10
Margarete Anna Ueberfuhr, Amalia Braun, Lutz Wiegrebe, Benedikt Grothe, Markus Drexl
Transcutaneous, electrical stimulation with electrodes placed on the mastoid processes represents a specific way to elicit vestibular reflexes in humans without active or passive subject movements, for which the term galvanic vestibular stimulation was coined. It has been suggested that galvanic vestibular stimulation mainly affects the vestibular periphery, but whether vestibular hair cells, vestibular afferents, or a combination of both are excited, is still a matter of debate. Galvanic vestibular stimulation has been in use since the late 18th century, but despite the long-known and well-documented effects on the vestibular system, reports of the effect of electrical stimulation on the adjacent cochlea or the ascending auditory pathway are surprisingly sparse...
March 18, 2017: Hearing Research
https://www.readbyqxmd.com/read/28323019/comparison-of-perceptual-properties-of-auditory-streaming-between-spectral-and-amplitude-modulation-domains
#11
Shimpei Yamagishi, Sho Otsuka, Shigeto Furukawa, Makio Kashino
The two-tone sequence (ABA_), which comprises two different sounds (A and B) and a silent gap, has been used to investigate how the auditory system organizes sequential sounds depending on various stimulus conditions or brain states. Auditory streaming can be evoked by differences not only in the tone frequency ("spectral cue": ΔFTONE, TONE condition) but also in the amplitude modulation rate ("AM cue": ΔFAM, AM condition). The aim of the present study was to explore the relationship between the perceptual properties of auditory streaming for the TONE and AM conditions...
March 17, 2017: Hearing Research
https://www.readbyqxmd.com/read/28286099/tinnitus-and-hyperacusis-contributions-of-paraflocculus-reticular-formation-and-stress
#12
Yu-Chen Chen, Guang-Di Chen, Benjamin D Auerbach, Senthilvelan Manohar, Kelly Radziwon, Richard Salvi
Tinnitus and hyperacusis are common and potentially serious hearing disorders associated with noise-, age- or drug-induced hearing loss. Accumulating evidence suggests that tinnitus and hyperacusis are linked to excessive neural activity in a distributed brain network that not only includes the central auditory pathway, but also brain regions involved in arousal, emotion, stress and motor control. Here we examine electrophysiological changes in two novel non-auditory areas implicated in tinnitus and hyperacusis: the caudal pontine reticular nucleus (PnC), involved in arousal, and the paraflocculus lobe of the cerebellum (PFL), implicated in head-eye coordination and gating tinnitus and we measure the changes in corticosterone stress hormone levels...
March 7, 2017: Hearing Research
https://www.readbyqxmd.com/read/28213134/speech-in-noise-perception-in-musicians-a-review
#13
REVIEW
Emily B J Coffey, Nicolette Mogilever, Robert J Zatorre
The ability to understand speech in the presence of competing sound sources is an important neuroscience question in terms of how the nervous system solves this computational problem. It is also a critical clinical problem that disproportionally affects the elderly, children with language-related learning disorders, and those with hearing loss. Recent evidence that musicians have an advantage on this multifaceted skill has led to the suggestion that musical training might be used to improve or delay the decline of speech-in-noise (SIN) function...
February 14, 2017: Hearing Research
https://www.readbyqxmd.com/read/28189838/auditory-perceptual-load-a-review
#14
REVIEW
Sandra Murphy, Charles Spence, Polly Dalton
Selective attention is a crucial mechanism in everyday life, allowing us to focus on a portion of incoming sensory information at the expense of other less relevant stimuli. The circumstances under which irrelevant stimuli are successfully ignored have been a topic of scientific interest for several decades now. Over the last 20 years, the perceptual load theory (e.g. Lavie, 1995) has provided one robust framework for understanding these effects within the visual modality. The suggestion is that successful selection depends on the perceptual demands imposed by the task-relevant information...
February 8, 2017: Hearing Research
https://www.readbyqxmd.com/read/28161584/analytical-and-numerical-modeling-of-the-hearing-system-advances-towards-the-assessment-of-hearing-damage
#15
REVIEW
Annalisa De Paolis, Marom Bikson, Jeremy T Nelson, J Alexander de Ru, Mark Packer, Luis Cardoso
Hearing is an extremely complex phenomenon, involving a large number of interrelated variables that are difficult to measure in vivo. In order to investigate such process under simplified and well-controlled conditions, models of sound transmission have been developed through many decades of research. The value of modeling the hearing system is not only to explain the normal function of the hearing system and account for experimental and clinical observations, but to simulate a variety of pathological conditions that lead to hearing damage and hearing loss, as well as for development of auditory implants, effective ear protections and auditory hazard countermeasures...
February 1, 2017: Hearing Research
https://www.readbyqxmd.com/read/28153668/prevalence-of-hearing-loss-and-tinnitus-in-iraq-and-afghanistan-veterans-a-chronic-effects-of-neurotrauma-consortium-study
#16
A A Swan, J T Nelson, B Swiger, C A Jaramillo, B C Eapen, M Packer, M J Pugh
The purpose of this study was to describe the prevalence of hearing loss and tinnitus in a cohort of Iraq and Afghanistan Veterans (IAV) with common post-deployment conditions, including traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), and other typical post-concussive conditions such as headaches and vertigo/dizziness. This retrospective observational study used data from the national Veterans Health Administration (VA) data repository from fiscal years 2001-2014. Veteran data was included if there were at least three years of VA care, with one or more years of care in 2007 or after...
January 31, 2017: Hearing Research
https://www.readbyqxmd.com/read/28286233/speech-intelligibility-and-subjective-benefit-in-single-sided-deaf-adults-after-cochlear-implantation
#17
Mareike Finke, Angelika Strauß-Schier, Eugen Kludt, Andreas Büchner, Angelika Illg
Treatment with cochlear implants (CIs) in single-sided deaf individuals started less than a decade ago. CIs can successfully reduce incapacitating tinnitus on the deaf ear and allow, so some extent, the restoration of binaural hearing. Until now, systematic evaluations of subjective CI benefit in post-lingually single-sided deaf individuals and analyses of speech intelligibility outcome for the CI in isolation have been lacking. For the prospective part of this study, the Bern Benefit in Single-Sided Deafness Questionnaire (BBSS) was administered to 48 single-sided deaf CI users to evaluate the subjectively perceived CI benefit across different listening situations...
May 2017: Hearing Research
https://www.readbyqxmd.com/read/28286100/the-gap-prepulse-inhibition-deficit-of-the-cortical-n1-p2-complex-in-patients-with-tinnitus-the-effect-of-gap-duration
#18
Yunseo Ku, Joong Woo Ahn, Chiheon Kwon, Do Youn Kim, Myung-Whan Suh, Moo Kyun Park, Jun Ho Lee, Seung Ha Oh, Hee Chan Kim
The present study aimed to investigate whether gap-prepulse inhibition (GPI) deficit in patients with tinnitus occurred in the N1-P2 complex of the cortical auditory evoked potential. Auditory late responses to the intense sound of the GPI paradigm were obtained from 16 patients with tinnitus and 18 age- and hearing loss-matched controls without tinnitus. The inhibition degrees of the N1-P2 complex were assessed at 100-, 50-, and 20-ms gap durations with tinnitus-pitch-matched and non-matched frequency background noises...
May 2017: Hearing Research
https://www.readbyqxmd.com/read/28284736/contributions-of-sensory-tuning-to-auditory-vocal-interactions-in-marmoset-auditory-cortex
#19
Steven J Eliades, Xiaoqin Wang
During speech, humans continuously listen to their own vocal output to ensure accurate communication. Such self-monitoring is thought to require the integration of information about the feedback of vocal acoustics with internal motor control signals. The neural mechanism of this auditory-vocal interaction remains largely unknown at the cellular level. Previous studies in naturally vocalizing marmosets have demonstrated diverse neural activities in auditory cortex during vocalization, dominated by a vocalization-induced suppression of neural firing...
May 2017: Hearing Research
https://www.readbyqxmd.com/read/28284735/isolating-spectral-cues-in-amplitude-and-quasi-frequency-modulation-discrimination-by-reducing-stimulus-duration
#20
Ewa Borucki, Bruce G Berg
This study investigated the psychophysical effects of distortion products in a listening task traditionally used to estimate the bandwidth of phase sensitivity. For a 2000 Hz carrier, estimates of modulation depth necessary to discriminate amplitude modulated (AM) tones and quasi-frequency modulated (QFM) were measured in a two interval forced choice task as a function modulation frequency. Temporal modulation transfer functions were often non-monotonic at modulation frequencies above 300 Hz. This was likely to be due to a spectral cue arising from the interaction of auditory distortion products and the lower sideband of the stimulus complex...
May 2017: Hearing Research
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