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Maturitas

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https://www.readbyqxmd.com/read/29279141/prescribing-gardening-and-conservation-activities-for-health-and-wellbeing-in-older-people
#1
EDITORIAL
Kerryn Husk, Rebecca Lovell, Ruth Garside
No abstract text is available yet for this article.
December 21, 2017: Maturitas
https://www.readbyqxmd.com/read/29292013/testing-ovarian-reserve-in-pre-menopausal-women-why-whom-and-how
#2
REVIEW
Agnieszka Podfigurna, Krzysztof Lukaszuk, Adam Czyzyk, Michal Kunicki, Marzena Maciejewska-Jeske, Grzegorz Jakiel, Blazej Meczekalski
Numerous social and environmental factors (environmental hazards, social factors such as education and career, higher economic status desired before the decision is made to have children) influence a women's decision to postpone pregnancy until late reproductive age. In turn, age is related to a fall in ovarian reserve. The main goal of testing ovarian reserve is the identification of women with so-called diminished ovarian reserve (DOR). Additionally, it provides assistance in the counselling of women who are planning to use assisted reproductive techniques (ART)...
November 22, 2017: Maturitas
https://www.readbyqxmd.com/read/29150063/lactose-avoidance-and-bone
#3
EDITORIAL
Bo Abrahamsen, Peter Vestergaard
No abstract text is available yet for this article.
November 3, 2017: Maturitas
https://www.readbyqxmd.com/read/29290220/diagnosis-and-management-of-vulvodynia-in-postmenopausal-women
#4
REVIEW
Pedro Vieira-Baptista, Gilbert Donders, Lynnette Margesson, Libby Edwards, Hope K Haefner, Faustino R Pérez-López
Vulvodynia, defined as vulvar pain or burning sensation for more than 3 months, without an identifiable cause, can occur at any age. In this paper, the authors address the classification, epidemiology, etiology, diagnosis, and treatment of this condition, focusing on postmenopausal women. In postmenopausal women, vulvar pain and dyspareunia can often be attributed to low levels of estrogen resulting in vulvovaginal atrophy. While correction of vulvovaginal atrophy is an important part of the management of these patients, it will usually be insufficient to manage vulvodynia...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290219/associations-of-obesity-and-weight-change-with-physical-and-mental-impairments-in-elderly-chinese-people
#5
Jingjing Zhu, Yong-Bing Xiang, Hui Cai, Honglan Li, Yu-Tang Gao, Wei Zheng, Xiao-Ou Shu
OBJECTIVE: To examine the associations between anthropometric measurements and functional impairments in a sample of urban elderly Chinese people. METHODS: In two population-based cohort studies, the Shanghai Women's Health Study (SWHS) and Shanghai Men's Health Study (SMHS), 11,505 men and 17,166 women aged 70-88 years at the time of the functional assessment were studied. Weight history was collected and anthropometric data were taken at study enrollment (from 1996 to 2000 for the SWHS, 2002-2006 for the SMHS)...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290218/shoulder-replacement-for-osteoarthritis-a-review-of-surgical-management
#6
REVIEW
Jay Pandya, Tamara Johnson, Adrian K Low
Osteoarthritis of the shoulder is caused by progressive cartilage wear of the glenohumeral joint. Its prevalence is increasing due to our ageing population and it may affect up to one-third of people over 60 years of age. Patients usually complain of pain with restricted shoulder movement and function. Initial treatment should be non-operative, such as activity modification, oral analgesics (e.g. non-steroidal anti-inflammatories) and possibly physical therapy or corticosteroid injections. Patients with ongoing severe pain and functional restriction despite non-operative treatment would be candidates for surgery, usually a shoulder replacement...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290217/variation-in-symptoms-of-depression-and-anxiety-in-midlife-women-by-menopausal-status
#7
Stephanie Mulhall, Ross Andel, Kaarin J Anstey
OBJECTIVES: To examine the association between menopausal status and the risk of symptoms of depression and anxiety in a community-based sample of Australian midlife women. STUDY DESIGN: Female participants (mean age 50.6±1.5) who were premenopausal (n=237), perimenopausal (n=249) or naturally postmenopausal (n=225) were drawn from the Personality and Total Health (PATH) Through Life Project, a longitudinal study. MAIN OUTCOME MEASURES: Symptoms of depression and anxiety were measured using the Goldberg Depression Scale and Goldberg Anxiety Scale...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290216/cardiovascular-disease-in-women-living-with-hiv-a-narrative-review
#8
REVIEW
Danielle Solomon, Caroline A Sabin, Patrick W G Mallon, Alan Winston, Shema Tariq
Advances in the treatment of HIV have led to increasing numbers of people living with HIV reaching older age. Age-related comorbid conditions, such as cardiovascular disease (CVD), are therefore of increasing importance in HIV clinical practice. Over half the global population of people living with HIV are female. We present a narrative literature review of 39 studies exploring CVD in women living with HIV (WLHIV), with particular reference to coronary heart disease, and focusing on: (1) epidemiology, (2) pathophysiology, (3) risk factors (including traditional risk factors and HIV-related risk factors), and (4) management...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290215/predictors-for-dislodgment-of-vaginal-pessary-within-one-year-in-women-with-pelvic-organ-prolapse
#9
Rachel Y K Cheung, Loreta L L Lee, Tony K H Chung, Symphorosa S C Chan
OBJECTIVES: To identify clinical risk factors for dislodgment of vaginal pessary within one year in women with symptomatic pelvic organ prolapse. STUDY DESIGN: This was a prospective observational study which recruited consecutive women with symptomatic pelvic organ prolapse in a tertiary urogynecology center. Basic demographics, clinical symptoms and staging of pelvic organ prolapse were assessed. A vaginal pessary was offered where appropriate. MAIN OUTCOME MEASURES: Demographics and clinical parameters were compared between women who were able to use a vaginal pessary for one year and those whose pessaries were dislodged within one year...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290214/dietary-management-of-dyslipidaemias-is-there-any-evidence-for-cardiovascular-benefit
#10
REVIEW
Panagiotis Anagnostis, Stavroula A Paschou, Dimitrios G Goulis, Vasilios G Athyros, Asterios Karagiannis
Specific dietary strategies are the mainstay of management in most cases of dyslipidaemia, prior to or simultaneously with the initiation of a lipid-lowering agent. The exact approach differs according to the type of dyslipidaemia. In particular, a reduction in carbohydrates (mainly foods with a high glycaemic index) and their substitution with mono- and polyunsaturated fatty acids is the main strategy in patients with high levels of triglycerides (Tg) and/or low levels of high-density lipoprotein cholesterol (HDL-c)...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290213/sex-hormone-levels-and-change-in-left-ventricular-structure-among-men-and-post-menopausal-women-the-multi-ethnic-study-of-atherosclerosis-mesa
#11
Vinita Subramanya, Di Zhao, Pamela Ouyang, Joao A Lima, Dhananjay Vaidya, Chiadi E Ndumele, David A Bluemke, Sanjiv J Shah, Eliseo Guallar, Chike C Nwabuo, Matthew A Allison, Susan R Heckbert, Wendy S Post, Erin D Michos
OBJECTIVE: Sex hormone (SH) levels may contribute to sex differences in the risk of heart failure with preserved ejection fraction (HFpEF). We examined the associations of SH levels with left ventricular mass (LVM) and mass (M):volume (V) ratio, which are risk markers for HFpEF. STUDY DESIGN: We studied 1941 post-menopausal women and 2221 men, aged 45-84 years, participating in the Multi-Ethnic Study of Atherosclerosis (MESA). Serum SH levels, cardiac magnetic resonance imaging (MRI) and ejection fraction (EF) ≥50% had been recorded at baseline (2000-2002)...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290212/the-sexual-health-approach-in-postmenopause-the-five-minutes-study
#12
Marcos J Cuerva, Daniel Gonzalez, Marta Canals, Borja Otero, Jose Angel Espinosa, Francisca Molero, Levent M Senturk, Nicolas Mendoza
OBJECTIVES: To determine whether actively addressing sexuality in a gynaecological consultation with menopausal patients improves the diagnosis of sexual problems. STUDY DESIGN: A multi-centre analytical cross-sectional study was conducted at 12 Spanish hospitals. In gynaecological consultations the usual medical histories were taken, except that, initially, issues relating to sexuality were omitted, unless the patients raised them. Then, after 5min, gynaecologists offered the possibility of talking about sexuality and asked about possible sexual problems...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290211/reverse-engineering-of-triple-negative-breast-cancer-cells-for-targeted-treatment
#13
Lena Bluemel, Marie-Kristin von Wahlde, Joke Tio, Ludwig Kiesel, Christof Bernemann
OBJECTIVE: Targeting the human epidermal growth factor receptor HER2 has increased survival in HER2-positive breast cancer patients. In the contrast, for triple-negative breast cancer (TNBC) patients, no targeted agents are available. We hypothesized that artificial overexpression of HER2 in TNBC cells might induce sensitivity to anti-HER2 agents in these cells. METHODS: TNBC cell lines were transduced using lentiviral HER2 overexpression particles. Functionality of HER2 was determined by protein analysis and localization studies...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290210/the-most-bothersome-symptom-of-vaginal-atrophy-evidence-from-the-observational-agata-study
#14
Federica Palma, Anjeza Xholli, Angelo Cagnacci
OBJECTIVES: Vaginal atrophy (VA) is a chronic medical condition. It is managed unsatisfactorily, despite its high prevalence and negative impact on female quality of life. In order to meet their needs, it would be useful to know what women perceive to be the most bothersome symptom (MBS) of VA. STUDY DESIGN: Cross-sectional, multicenter study of 913 postmenopausal women consulting 22 gynecological outpatient services. MAIN OUTCOME MEASURES: Prevalence of the MBS perceived by postmenopausal women of different age and vaginal condition...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290209/self-compassion-physical-fitness-and-climacteric-symptoms-in-oophorectomized-brca1-2-mutation-carriers
#15
Marieke Arts-de Jong, Liselore L van Westerop, Nicoline Hoogerbrugge, Leon F Massuger, Angela H Maas, Maria H van Beek, Joanne A de Hullu
OBJECTIVES: To reduce the risk of ovarian cancer, BRCA1/2 mutation carriers are advised to undergo salpingo-oophorectomy (RRSO) around the age of 40 years. This may induce severe climacteric symptoms, potentially lowering their quality of life. Personal positive resources such as physical fitness and self-compassion may help women to deal with these symptoms. We investigated the association of climacteric symptoms with self-compassion and physical fitness in oophorectomized BRCA1/2 mutation carriers...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29290208/quality-of-life-among-postmenopausal-women-enrolled-in-the-minnesota-green-tea-trial
#16
Allison Dostal Webster, Deborah A Finstad, Mindy S Kurzer, Carolyn J Torkelson
BACKGROUND: Postmenopausal symptomatology has not been elucidated in large, long-term human clinical trials. Our objective was to measure quality of life in postmenopausal women aged 50-70 years. METHODS: A Menopause-Specific Quality of Life-Intervention (MENQOL) questionnaire was completed by women enrolled in the Minnesota Green Tea Trial (n=932) to assess vasomotor, physical, sexual, and psychosocial symptoms in the years following menopause. Responses were coded; mean overall and domain scores ranged from 1 to 8...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29169589/vitamin-d-deficiency-is-associated-with-metabolic-syndrome-in-postmenopausal-women
#17
Eneida Boteon Schmitt, Jorge Nahas-Neto, Flavia Bueloni-Dias, Priscila Ferreira Poloni, Claudio Lera Orsatti, Eliana Aguiar Petri Nahas
OBJECTIVE: To evaluate the association between vitamin D (VD) deficiency and risk factors for metabolic syndrome (MetS) in postmenopausal women. STUDY DESIGN: Observational, cross-sectional cohort study. MAIN OUTCOME MEASURES: In this study, 463 women, aged 45-75 years, with amenorrhea >12months, without VD supplementation or established cardiovascular disease were included. Clinical and anthropometric data were collected. Biochemical parameters, including total cholesterol (TC), HDL, LDL, triglycerides, glucose, insulin and 25-hydroxyvitamin-D [25(OH)D] were measured...
January 2018: Maturitas
https://www.readbyqxmd.com/read/29169588/changes-in-hormonal-and-metabolic-parameters-in-transgender-subjects-on-cross-sex-hormone-therapy-a-cohort-study
#18
Roberto Vita, Salvatore Settineri, Marco Liotta, Salvatore Benvenga, Francesco Trimarchi
OBJECTIVES: Gender identity disorder is defined as a strong and persistent cross-gender identification that is associated with a remarkable uneasiness of living in an incongruent gender (gender dysphoria). We performed a retrospective study on the hormonal and metabolic effects of cross-sex hormone therapy (CSHT) in a small cohort of transgender patients. STUDY DESIGN: Retrospective study. MEAN OUTCOME MEASURES: Hormonal and biochemical parameters at baseline (i...
January 2018: Maturitas
https://www.readbyqxmd.com/read/29169587/multimorbidity-and-perceived-stress-a-population-based-cross-sectional-study-among-older-adults-across-six-low-and-middle-income-countries
#19
Brendon Stubbs, Davy Vancampfort, Nicola Veronese, Patricia Schofield, Pao-Yen Lin, Ping-Tao Tseng, Marco Solmi, Trevor Thompson, André F Carvalho, Ai Koyanagi
BACKGROUND: Stress in chronic conditions or multimorbidity (≥2 chronic conditions) has been reported to affect clinical outcomes but there are no studies on the association between stress and chronic conditions/multimorbidity among older adults in low- and middle-income countries (LMICs). Thus, we investigated this association among adults aged ≥50 years across six LMICs. METHODS: A cross-sectional analysis using data from the World Health Organization's Study on Global Ageing and Adult Health (China, Ghana, India, Mexico, Russia, South Africa) was conducted...
January 2018: Maturitas
https://www.readbyqxmd.com/read/29169586/the-prevalence-of-urinary-incontinence-in-nulliparous-adolescent-and-middle-aged-women-and-the-associated-risk-factors-a-systematic-review
#20
REVIEW
Sania Almousa, Alda Bandin van Loon
Urinary incontinence (UI) has been defined as the complaint of involuntary loss of urine. There is a general belief that UI is experienced almost exclusively by the elderly and women who have given birth. However, epidemiological studies report that young women who are nulliparous also experience UI. The aim of this study was to systematically review studies investigating the prevalence of UI in nulliparous adolescent and middle-aged women and to provide an overview of risk factors associated with UI. The electronic databases PubMed, EMBASE, CINAHL, and Cochrane Library were systematically searched for eligible studies...
January 2018: Maturitas
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