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Maturitas

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https://www.readbyqxmd.com/read/28081964/interventions-to-reduce-inappropriate-polypharmacy-implications-for-research-and-practice
#1
EDITORIAL
Tim Johansson, Maria Flamm, Andreas Sönnichsen, Jochen Schuler
No abstract text is available yet for this article.
December 26, 2016: Maturitas
https://www.readbyqxmd.com/read/28041602/serum-vitamin-d-and-sex-hormones-levels-in-men-and-women-the-multi-ethnic-study-of-atherosclerosis-mesa
#2
Di Zhao, Pamela Ouyang, Ian H de Boer, Pamela L Lutsey, Youssef M K Farag, Eliseo Guallar, David S Siscovick, Wendy S Post, Rita R Kalyani, Kevin L Billups, Erin D Michos
INTRODUCTION: 25-hydroxyvitamin D [25(OH)D] deficiency has been associated with low testosterone levels in men, but there are conflicting reports of its associations with sex hormones in women. Less is known about whether these associations are independent of adiposity and lifestyle factors, and whether they differ by race/ethnicity. AIM: To examine associations of 25(OH)D concentrations with sex hormone levels. METHODS: Cross-sectional analysis of 3017 men and 2929 women in a multi-ethnic cohort...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041601/higher-intake-of-cryptoxanthin-is-related-to-low-body-mass-index-and-body-fat-in-japanese-middle-aged-women
#3
Asuka Hirose, Masakazu Terauchi, Miho Hirano, Mihoko Akiyoshi, Yoko Owa, Kiyoko Kato, Toshiro Kubota
OBJECTIVES: The prevalence of cardiovascular diseases increases with age, especially in postmenopausal women. In this study, we investigated the dietary patterns associated with body mass and body fat in Japanese middle-aged women. STUDY DESIGN: Cross-sectional. MAIN OUTCOME MEASURES: This study used baseline data collected in a previous study in 88 women aged 40-60 years. Participants were assessed for age, menopausal status, lifestyle factors, body composition, and dietary habits using a brief-type self-administered diet history questionnaire, which provides information on the amounts of nearly 100 nutritional factors consumed during the previous month...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041600/study-protocol-for-the-option-randomised-controlled-trial-on-the-effect-of-prioritising-treatment-goals-among-older-patients-with-cancer-in-a-palliative-setting
#4
M E Stegmann, J Schuling, T J N Hiltermann, A K L Reyners, H Burger, M Y Berger, A J Berendsen
PURPOSE: Traditionally, general practitioners (GPs) are not involved in cancer-related treatment decisions, despite their often long relationship with patients, and their unique position to explore patients' values, especially with older patients. Therefore, we designed a randomised controlled trial to study the effect, on self-efficacy related to treatment decisions, of a conversation about treatment goals between GPs and patients with cancer in a palliative setting. METHODS: We aim to include 168 patients aged ≥70 years with a diagnosis of non-curable cancer, due to consult their oncologist about treatment options...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041599/influence-of-equol-and-resveratrol-supplementation-on-health-related-quality-of-life-in-menopausal-women-a-randomized-placebo-controlled-study
#5
Sergio Davinelli, Giovanni Scapagnini, Fulvio Marzatico, Vincenzo Nobile, Nicola Ferrara, Graziamaria Corbi
OBJECTIVE: This study was designed to evaluate the effects of equol and resveratrol supplementation on health-related quality of life (HRQoL) in otherwise healthy menopausal women with hot flashes, anxiety and depressive symptoms. METHODS: Sixty recently menopausal women aged 50-55 years were randomized in a 12-week, placebo-controlled trial to receive 200mg of fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day). The primary outcome was the change in score on the Menopause Rating Scale (MRS), used to evaluate the severity of age-/menopause-related complaints...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041598/premature-ovarian-insufficiency-and-perinatal-parameters-a-retrospective-case-control-study
#6
S Sadrzadeh, R C Painter, Y M van Kasteren, D D M Braat, C B Lambalk
OBJECTIVE: The peak number of oocytes is reached during intrauterine development, after which numbers decline until reserves are depleted and a woman enters menopause. In premature ovarian insufficiency (POI), the process of follicle depletion occurs at a young age (generally taken as 40 years); the condition affects about 1% of women. In this study, we investigate whether women with POI had experienced a different perinatal milieu, as reflected in their birth weight or prematurity. STUDY DESIGN: In this retrospective case-control study, we evaluated whether women diagnosed with POI had a different birth weight or prematurity rate (<37 weeks) compared with women aged over 40 at natural menopause (the controls)...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041597/the-effects-of-vitamin-b-on-the-immune-cytokine-network-and-their-involvement-in-depression
#7
REVIEW
Kathleen Mikkelsen, Lily Stojanovska, Monica Prakash, Vasso Apostolopoulos
Increasing evidence indicates that there are various interactions between the nervous system and the immune system, and that the immune system plays an important role in the pathogenesis of depression. Pro-inflammatory cytokines (such as IL-1, IL-6, TNF-α) have been implicated in the neurobiological manifestations of depression. The immune/cytokine network has a powerful influence on the brain. In addition, deficiency in B vitamins has been linked to depression. Hence, greater knowledge of how immune cells change in the presence of vitamin B derivatives could improve understanding of how immune changes may correlate with depression, all of which are discussed herein...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041596/clinical-settings-in-knee-osteoarthritis-pathophysiology-guides-treatment
#8
REVIEW
Gabriel Herrero-Beaumont, Jorge A Roman-Blas, Olivier Bruyère, Cyrus Cooper, John Kanis, Stefania Maggi, René Rizzoli, Jean-Yves Reginster
Osteoarthritis (OA) is the most common chronic joint disorder and its prevalence increases rapidly during midlife. Complex interactions of genetic alterations, sex hormone deficit, and aging with mechanical factors and systemic inflammation-associated metabolic syndrome lead to joint damage. Thus, the expression of a clinical phenotype in the early stages of OA relies on the main underlying pathway and predominant joint tissue involved at a given time. Moreover, OA often coexists with other morbidities in the same patient, which in turn condition the OA process...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041595/factors-associated-with-educational-mobility-in-mid-age-australian-women
#9
Leigh R Tooth, Gita D Mishra
The educational mobility of mid-age women is rarely studied. We analysed the baseline socio-economic position (SEP) and health factors associated with obtaining further education in 4117 mid-age Australian women between 1996 and 2010 (aged 45-50 at baseline, 62-67 at follow-up) from a population-based study. Women either unemployed or working part-time at baseline had higher odds of a stable low and middle education over time (ORs ranging from 1.61 to 3.86) versus educational mobility. Apart from obesity, characteristics that may signal an unhealthy lifestyle in early mid-life were not useful indicators of women's future educational mobility...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041594/malignant-and-borderline-epithelial-ovarian-tumors-in-the-pediatric-and-adolescent-population
#10
Dimitrios Nasioudis, Michail Alevizakos, Kevin Holcomb, Steven S Witkin
OBJECTIVES: Malignant and borderline ovarian tumors of epithelial origin are rarely encountered among prepubertal girls and adolescents. The aim of this population-based study was to elucidate their clinicopathological characteristics and prognosis using a multi-institutional tumor registry. STUDY DESIGN AND OUTCOMES: The National Cancer Institute's Surveillance, Epidemiology, and End Results database was accessed and a cohort of females aged <=19years old, diagnosed between 1988 and 2013 with a borderline ovarian tumor (BOT) or a malignant epithelial ovarian carcinoma (EOC) was accessed...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041593/differential-expression-of-sex-hormone-receptors-in-abdominal-aortic-aneurysms
#11
Christina Villard, Per Eriksson, Malin Kronqvist, Mariette Lengquist, Carl Jorns, Johan Hartman, Joy Roy, Rebecka Hultgren
OBJECTIVE: Male sex is a significant risk factor for abdominal aortic aneurysm (AAA). Female sex hormones have been reported to prevent aneurysm formation in animal models. The study aims to describe the expression profile of sex hormone receptors in the aneurysm wall of men and women with AAA and compare with unaffected controls. METHODS: Aneurysm wall biopsies were obtained during elective open repair of AAA in men and women (n=16+16). Aortic vessel wall from controls were obtained at organ donation (n=6)...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041592/visual-impairment-at-baseline-is-associated-with-future-poor-physical-functioning-among-middle-aged-women-the-study-of-women-s-health-across-the-nation-michigan-site
#12
Navasuja Chandrasekaran, Sioban Harlow, Sayoko Moroi, David Musch, Qing Peng, Carrie Karvonen-Gutierrez
OBJECTIVES: Emerging evidence suggests that the prevalence rates of poor functioning and of disability are increasing among middle-aged individuals. Visual impairment is associated with poor functioning among older adults but little is known about the impact of vision on functioning during midlife. The objective of this study was to assess the impact of visual impairment on future physical functioning among middle-aged women. STUDY DESIGN: In this longitudinal study, the sample consisted of 483 women aged 42 to 56 years, from the Michigan site of the Study of Women's Health Across the Nation...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041591/hot-flashes-and-midlife-symptoms-in-relation-to-levels-of-salivary-cortisol
#13
Linda M Gerber, Lynnette L Sievert, Joseph E Schwartz
OBJECTIVES: This study examined the relationship between salivary cortisol levels and hot flashes during midlife. Previous studies have shown that cortisol levels increase with hot flashes in the laboratory, and higher cortisol levels have been associated with more severe hot flashes. Salivary cortisol levels were also examined in relation to total number of midlife symptoms. METHODS: Women aged 40-60 years (n=109) reported the presence or absence of 23 symptoms, including hot flashes, during the previous 2 weeks...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041590/patient-reported-outcome-measures-of-quality-of-end-of-life-care-a-systematic-review
#14
REVIEW
Tara Kearns, Nicola Cornally, William Molloy
End-of-life (EoL) care(1) is increasingly used as a generic term in preference to palliative care or terminal care, particularly with reference to individuals with chronic disease, who are resident in community and long-term care (LTC) settings. This review evaluates studies based on patient reported outcome measures (PROMS) of quality of EoL care across all health-care settings. From 1041 citations, 12 studies were extracted by searches conducted in EBSCO, Scopus, Web of Science, PubMed, Cochrane, Open Grey and Google Scholar databases...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041589/ovarian-aging-in-women-with-diabetes-an-overview
#15
REVIEW
Melissa F Wellons, Juliana J Matthews, Catherine Kim
Type 2 diabetes is a global epidemic, and the prevalence and incidence of type 1 diabetes are increasing. The negative effects of diabetes on kidneys, nerves, and vessels are well established. The effect of diabetes on reproductive function is less well understood, but important to characterize, given the increasing numbers of young women with diabetes. In this review, we summarize the available literature on how women with diabetes experience ovarian aging, from menarche to menopause. We report that women with type 1 diabetes appear more likely to have ovarian dysfunction, manifested by delayed menses, menstrual irregularities, and possibly earlier menopause...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041588/diagnosing-early-cognitive-decline-when-how-and-for-whom
#16
REVIEW
Charlotte L Allan, Sophie Behrman, Klaus P Ebmeier, Vyara Valkanova
Mild cognitive impairment (MCI) is a term used to describe cognitive impairment in one or more cognitive domains that is greater than any expected age-related changes, but not of the magnitude to warrant a diagnosis of dementia. This review considers how early cognitive decline is diagnosed, focusing on the use of neuropsychological tests and neuroimaging, as well as the differential diagnosis. Potential treatments, including secondary prevention, post-diagnostic support and self-help are discussed. Finally, medico-legal matters such as driving, lasting power of attorney and employment are outlined...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041587/inflammation-and-sarcopenia-a-systematic-review-and-meta-analysis
#17
REVIEW
Giulia Bano, Caterina Trevisan, Sara Carraro, Marco Solmi, Claudio Luchini, Brendon Stubbs, Enzo Manzato, Giuseppe Sergi, Nicola Veronese
Inflammatory cytokines have been shown to prompt muscle wasting, ultimately stimulating protein catabolism and suppressing muscle synthesis. However, the possible association between inflammatory parameters and sarcopenia is poorly understood. We therefore aimed to summarize the current evidence about this topic with a meta-analysis of studies reporting serum inflammatory parameters in patients with sarcopenia vs. people without sarcopenia (controls). An electronic PubMed and Scopus search through to 09/01/2016 and meta-analysis of cross-sectional studies comparing serum levels of inflammatory cytokines between patients with sarcopenia and controls was made, calculating random-effects standardized mean differences (SMDs) ±95% confidence intervals (CIs) as the effect size...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041586/thyroid-nodules-%C3%AE-guide-to-assessment-treatment-and-follow-up
#18
REVIEW
Stavroula Α Paschou, Andromachi Vryonidou, Dimitrios G Goulis
Thyroid nodules constitute by far the most common disorder of the endocrine system. Epidemiological studies have indicated that approximately 5% of women and 1% of men resident in iodine-sufficient areas have palpable thyroid nodules. However, by the age of 60 years about 50% of the general population is estimated to have at least one thyroid nodule. Indeed, the reported prevalence of a "thyroid incidentaloma" is up to 70% when neck/carotid artery ultrasound, computed tomography (CT) or magnetic resonance imaging (MRI) is performed for other indications...
February 2017: Maturitas
https://www.readbyqxmd.com/read/27986333/comments-on-tocotrienols-health-and-ageing
#19
LETTER
Kok-Yong Chin, Ima-Nirwana Soelaiman
No abstract text is available yet for this article.
February 2017: Maturitas
https://www.readbyqxmd.com/read/27765380/optimising-glycemic-index-in-diets-for-older-people
#20
EDITORIAL
Alan W Barclay
No abstract text is available yet for this article.
February 2017: Maturitas
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