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Maturitas

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https://www.readbyqxmd.com/read/28705438/patients-expectations-and-preferences-regarding-cancer-follow-up-care
#1
REVIEW
D Brandenbarg, A J Berendsen, G H de Bock
INTRODUCTION: Most survivors of cancer enter a follow-up routine after their treatment, the aim of which is to detect recurrence, provide psychological support, monitor treatment-related side-effects, and to evaluate care. Due to rising numbers of people with cancer and better survival of these patients, current follow-up routines are under pressure. We reviewed the literature on patients' expectations and preferences regarding this care. METHODS: We systematically searched the databases of Pubmed, CINAHL, and PsychInfo...
July 5, 2017: Maturitas
https://www.readbyqxmd.com/read/28687135/advance-care-planning-within-survivorship-care-plans-for-older-cancer-survivors-a-systematic-review
#2
REVIEW
Rónán O'Caoimh, Nicola Cornally, Ronan O'Sullivan, Ruth Hally, Elizabeth Weathers, Amanda H Lavan, Tara Kearns, Alice Coffey, Ciara McGlade, D William Molloy
Advances in the medical treatment of cancer have increased the number of survivors, particularly among older adults, who now represent the majority of these. Survivorship care plans (SCPs) are documents that cancer patients receive summarising their care, usually at the end of treatment but preferably from initial diagnosis. These may increase patient satisfaction and represent an opportunity to initiate preventative strategies and address future care needs. Advance care planning (ACP), incorporating advance healthcare decision-making, including formal written directives, increases satisfaction and end-of-life care...
June 23, 2017: Maturitas
https://www.readbyqxmd.com/read/28619461/predictability-of-brca1-2-mutation-status-in-patients-with-ovarian-cancer-how-to-select-women-for-genetic-testing-in-middle-income-countries
#3
Natalia Teixeira, Simone Maistro, Maria Del Pilar Estevez Diz, Marian J Mourits, Jan C Oosterwijk, Maria Aparecida Koike Folgueira, Geertruida H de Bock
OBJECTIVES: To evaluate the accuracy of algorithms for predicting BRCA1/2 germ-line mutation carrier probability, and to identify factors that could improve their performance among Brazilian women with ovarian cancer (OC). STUDY DESIGN: In this cross-sectional study, we enrolled patients (unselected for family history of cancer) undergoing treatment or follow-up for OC in a single centre in Brazil. Clinical and demographic data, including family history of cancer, were obtained...
June 4, 2017: Maturitas
https://www.readbyqxmd.com/read/28602465/the-management-of-sexuality-intimacy-and-menopause-symptoms-sims-after-prophylactic-bilateral-salpingo-oophorectomy-how-to-maintain-sexual-health-in-previvors
#4
REVIEW
Mehida Alexandre, Jonathan Black, Margaret Whicker, Mary Jane Minkin, Elena Ratner
"Previvors", or "pre-survivors", are individuals who do not have cancer but have a genetic predisposition to cancer. One such example is women with BRCA mutations. As a result of their predisposition to cancer, many will undergo a bilateral salpingo-oophorectomy when they are premenopausal. For premenopausal women, the removal of ovaries results in the depletion of estrogen, immediate menopause, and, in many cases, resultant Sexuality, Intimacy, and Menopausal Symptoms (SIMS). Furthermore, they may undergo changes in body image...
June 3, 2017: Maturitas
https://www.readbyqxmd.com/read/28583397/long-term-cardiovascular-health-in-adult-cancer-survivors
#5
REVIEW
W R Naaktgeboren, M Linschoten, A de Graeff, A V Rhenen, M J Cramer, F W Asselbergs, A H E M Maas, A J Teske
The number of cancer survivors has tremendously increased over the past decades as a result of aging of the population and improvements in early cancer detection and treatment. Ongoing successes in cancer treatment are expected to result in a further increase in the number of long-term survivors. However, cancer treatment can have detrimental cardiovascular side-effects that impact morbidity and mortality, reducing quality of life in cancer survivors. The spectrum of radiotherapy- and chemotherapy-induced cardiovascular disease is broad, varying from subclinical valvular dysfunction to overt congestive heart failure, and such effects may not be apparent for more than twenty years after the initial cancer treatment...
May 21, 2017: Maturitas
https://www.readbyqxmd.com/read/28551081/exposure-to-stress-across-the-life-course-and-its-association-with-anxiety-and-depressive-symptoms-results-from-the-australian-women-s-wellness-after-cancer-program-wwacp
#6
Charrlotte Seib, Alexandra McCarthy, Amanda McGuire, Janine Porter-Steele, Sarah Balaam, Robert S Ware, Debra Anderson
OBJECTIVES: Earlier life stressors can increase the risk of persistent anxiety and depressive symptoms in women after cancer, though our understanding of the underlying mechanisms is limited. In this study, we tested alternative life course models to determine which best described associations between exposure to stressors in childhood, adolescence, and adulthood, and self-reported health in women previously treated for breast, gynaecological, and blood cancer. STUDY DESIGN: Data were drawn from 351 Australian women within 2 years of completing active cancer treatment who were participating in the Women's Wellness After Cancer Program (WWACP) randomised controlled trial...
May 19, 2017: Maturitas
https://www.readbyqxmd.com/read/28545906/optimizing-diet-and-nutrition-for-cancer-survivors-a-review
#7
REVIEW
Niki Mourouti, Demosthenes B Panagiotakos, Elias A Kotteas, Konstantinos N Syrigos
The number of cancer survivors is increasing and they are often highly motivated to search for information about nutrition and about physical activity in order to try to improve their treatment outcomes, quality of life and overall survival. In the light of these concerns, the World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) as well as the American Cancer Society recommend a largely plant-based diet with limited consumption of red and processed meat, and limited consumption of alcohol, as well as the maintenance of a healthy weight throughout life and regular engagement in physical activity...
May 19, 2017: Maturitas
https://www.readbyqxmd.com/read/28551082/gynaecological-care-after-stem-cell-transplant-an-overview
#8
REVIEW
Annabelle Brennan, Martha Hickey
Haematopoietic stem cell transplants are an important treatment for haematological malignancies. With increasing efficacy of treatment, it has become important to provide comprehensive long-term follow-up by experienced specialists in a multidisciplinary setting. This article gives an overview of the gynaecological implications of haematopoietic stem cell transplants, including appropriate pre-treatment counselling, the development of menopausal symptoms, bone loss, genital graft-versus-host disease and secondary genital malignancies...
May 17, 2017: Maturitas
https://www.readbyqxmd.com/read/28545905/resveratrol-alleviates-oxidative-damage-in-enteric-neurons-and-associated-gastrointestinal-dysfunction-caused-by-chemotherapeutic-agent-oxaliplatin
#9
Elizabeth L Donald, Lily Stojanovska, Vasso Apostolopoulos, Kulmira Nurgali
Oxaliplatin is a first-line chemotherapeutic agent used for the treatment of colorectal cancer. Its use is associated with severe gastrointestinal (GI) side-effects, associated with oxidative damage and neurotoxicity to the enteric neurons. Resveratrol is a potent anti-oxidant that has been shown to protect against oxidative damage and neurotoxicity in other neurons and could therefore prevent oxaliplatin-induced damage to enteric neurons. We determined whether co-administration of resveratrol with oxaliplatin alleviates enteric neuron toxicity and GI dysfunction in mice...
May 17, 2017: Maturitas
https://www.readbyqxmd.com/read/28551083/the-effects-of-yoga-and-self-esteem-on-menopausal-symptoms-and-quality-of-life-in-breast-cancer-survivors-a-secondary-analysis-of-a-randomized-controlled-trial
#10
Anna K Koch, Sybille Rabsilber, Romy Lauche, Sherko Kümmel, Gustav Dobos, Jost Langhorst, Holger Cramer
OBJECTIVES: Previous research has found that yoga can enhance quality of life and ease menopausal symptoms of breast cancer survivors. The study examined whether self-esteem mediated the effects of yoga on quality of life, fatigue and menopausal symptoms, utilizing validated outcome measures. STUDY DESIGN: This is a secondary analysis of a randomized controlled trial comparing the effects of yoga with those of usual care in 40 breast cancer survivors who suffered from menopausal symptoms...
May 13, 2017: Maturitas
https://www.readbyqxmd.com/read/28545907/impact-of-chemotherapy-on-gastrointestinal-functions-and-the-enteric-nervous-system
#11
REVIEW
Jonathan Escalante, Rachel M McQuade, Vanesa Stojanovska, Kulmira Nurgali
Chemotherapy is the main treatment for many cancers, including colorectal cancer, a type of cancer with some of the highest prevalence and mortality rates worldwide. Although chemotherapeutic drugs have greatly improved the survival rates of cancer patients, there are many side-effects associated with their use. The gastrointestinal side-effects of chemotherapy often lead to dose reduction or even discontinuation of treatment, which in turn affects the clinical outcome. Gastrointestinal side-effects, such as chemotherapy-induced diarrhea and constipation, may persist many years after treatment, greatly reducing quality of life...
May 10, 2017: Maturitas
https://www.readbyqxmd.com/read/28528727/sexual-inactivity-in-partnered-female-cancer-survivors
#12
Jennifer L Marino, Christobel M Saunders, Martha Hickey
OBJECTIVE: To measure sexual activity in a clinic population of partnered female cancer survivors, and to better understand reasons for sexual inactivity in this population. MATERIALS AND METHODS: Partnered peri- or post-menopausal cancer survivors seen at a specialty clinic for menopause symptoms after cancer completed Fallowfield's Sexual Activity Questionnaire, quality of life measures (the Functional Assessment of Cancer Therapy General, Breast Cancer, and Endocrine Symptom Scales), and the Greene Climacteric Scale...
May 9, 2017: Maturitas
https://www.readbyqxmd.com/read/28515012/breast-cancer-and-exercise-the-role-of-adiposity-and-immune-markers
#13
REVIEW
Supa Pudkasam, Kathy Tangalakis, Nanthapan Chinlumprasert, Vasso Apostolopoulos, Lily Stojanovska
Currently, breast cancer accounts for a quarter of all cancers and 15% of cancer-specific deaths amongst females. The global occurrence of breast cancer has increased in the last decade whilst the mortality rate has decreased. Exercise can be beneficial to breast cancer patients through changes in adiposity and immune responses. Even though there is some evidence supporting the improvement of fat metabolism and immune function after an exercise program in breast cancer, randomized controlled studies are limited and require further comprehensive analysis in this population group...
May 8, 2017: Maturitas
https://www.readbyqxmd.com/read/28487092/corrigendum-to-the-trajectory-of-negative-mood-and-depressive-symptoms-over-two-decades-maturitas-95-2017-36-41
#14
Katherine E Campbell, Lorraine Dennerstein, Mark Tacey, Cassandra E Szoeke
No abstract text is available yet for this article.
May 6, 2017: Maturitas
https://www.readbyqxmd.com/read/28483346/bisphosphonates-or-denosumab-discontinuation-and-risk-of-fractures-response-to-the-letter-by-anastasilakis-et-al
#15
LETTER
Panagiotis Anagnostis, Stavroula A Paschou, Gesthimani Mintziori, Iuliana Ceausu, Herman Depypere, Irene Lambrinoudaki, Alfred Mueck, Faustino R Pérez-López, Margaret Rees, Levent M Senturk, Tommaso Simoncini, John C Stevenson, Petra Stute, Florence A Trémollieres, Dimitrios G Goulis
No abstract text is available yet for this article.
April 28, 2017: Maturitas
https://www.readbyqxmd.com/read/28495014/bisphosphonates-or-denosumab-discontinuation-and-risk-of-fractures
#16
LETTER
Athanasios D Anastasilakis, Maria P Yavropoulou, Polyzois Makras
No abstract text is available yet for this article.
April 27, 2017: Maturitas
https://www.readbyqxmd.com/read/28477990/the-mechanisms-tumor-cells-utilize-to-evade-the-host-s-immune-system
#17
REVIEW
Nyanbol Kuol, Lily Stojanovska, Kulmira Nurgali, Vasso Apostolopoulos
The immune system plays an essential role in the tumor progression; not only can it inhibit tumor growth but it can also promote tumor growth by establishing a favorable environment. Tumor cells utilize several strategies to evade the host's immune system, including expression of immunosuppressive molecules such as PD-L1, IDO and siglec-9. In addition, tumor cells not only regulate the recruitment and development of immunosuppressive forces to influence the tumor microenvironment but also shift the phenotype and function of normal immune cells from a possibly anti-tumor state to a pro-tumor state...
April 27, 2017: Maturitas
https://www.readbyqxmd.com/read/28610687/assessing-the-thickness-of-the-vaginal-wall-and-vaginal-mucosa-in-pre-menopausal-versus-post-menopausal-women-by-transabdominal-ultrasound-a-feasibility-study
#18
Adrian Balica, Daniella Wald-Spielman, Katherine Schertz, Susan Egan, Gloria Bachmann
OBJECTIVE: As life expectancy increases, the number of women reporting adverse genito-urinary symptoms (genitourinary syndrome of menopause; GSM) from menopause, including vaginal dryness and sexual pain, also will increase. Current objective measurements of vaginal atrophy such as maturation index require vaginal swabs and are invasive; at present, no minimally invasive measurements exist. The purpose of this study was to assess whether total vaginal wall thickness (TVT) and total vaginal mucosa thickness (TMT) as measured by transabdominal ultrasound could qualify as additional objective markers of vaginal wall thinning which could be related to menopausal status...
August 2017: Maturitas
https://www.readbyqxmd.com/read/28610686/levels-of-physical-activity-and-sleep-patterns-among-older-people-with-dementia-living-in-long-term-care-facilities-a-24-h-snapshot
#19
Wendy Moyle, Cindy Jones, Jenny Murfield, Brian Draper, Elizabeth Beattie, David Shum, Lukman Thalib, Siobhan O'Dwyer, Cindy M Mervin
OBJECTIVES: To objectively measure over a 24-h period the daytime and nighttime levels of physical activity and sleep patterns of older people with dementia living in long-term care facilities. STUDY DESIGN: Nested within a larger research program, this cross-sectional study involved 415 residents, aged ≥60 years, with a documented diagnosis of dementia, from 28 long-term care facilities in south-east Queensland, Australia. MAIN OUTCOME MEASURES: Residents wore SenseWear(®) activity armbands continuously for 24h, with data recorded for: step count; total energy expenditure; metabolic equivalent of task (MET); and the amount of time spent physically active, lying down, awake, and asleep...
August 2017: Maturitas
https://www.readbyqxmd.com/read/28610685/the-overweight-paradox-in-the-prognosis-of-acute-coronary-syndrome-for-patients-with-heart-failure-a-truth-for-all-a-10-year-follow-up-study
#20
Matina Kouvari, Christina Chrysohoou, Eleptherios Tsiamis, Hara Kosyfa, Lemonia Kalogirou, Androniki Filippou, Stelios Iosifidis, Panagiotis Aggelopoulos, Christos Pitsavos, Dimitris Tousoulis
OBJECTIVES: In established acute coronary syndrome (ACS) with major complications (i.e. heart failure), overweight/obese patients usually have a survival advantage. To what extent this is irrespective of other characteristics remains inconclusive. The role of body mass index (BMI) in ACS prognosis (fatal/recurrent non-fatal cardiac episodes) and background potential interactions were evaluated. STUDY DESIGN: In 2006-2009, 1000 consecutive patients, hospitalized at First Cardiology Clinic of Athens with a diagnosis of ACS were enrolled in the study...
August 2017: Maturitas
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