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Maturitas

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https://www.readbyqxmd.com/read/28209237/vitamin-d-prescribing-in-older-people-in-the-uk-depends-on-postcode
#1
EDITORIAL
Thomas R Hill, Terry J Aspray
No abstract text is available yet for this article.
January 25, 2017: Maturitas
https://www.readbyqxmd.com/read/28173974/dementia-overtakes-heart-disease-as-the-leading-cause-of-death-but-does-this-mean-that-incidence-has-increased
#2
EDITORIAL
John M Starr
No abstract text is available yet for this article.
January 17, 2017: Maturitas
https://www.readbyqxmd.com/read/28081964/interventions-to-reduce-inappropriate-polypharmacy-implications-for-research-and-practice
#3
EDITORIAL
Tim Johansson, Maria Flamm, Andreas Sönnichsen, Jochen Schuler
No abstract text is available yet for this article.
December 26, 2016: Maturitas
https://www.readbyqxmd.com/read/28159064/vasomotor-symptoms-and-metabolic-syndrome
#4
REVIEW
Pauliina Tuomikoski, Hanna Savolainen-Peltonen
A vast majority of menopausal women suffer from vasomotor symptoms, such as hot flushes and night sweats, the mean duration of which may be up to 7-10 years. In addition to a decreased quality of life, vasomotor symptoms may have an impact on overall health. Vasomotor symptoms are associated with overactivity of the sympathetic nervous system, and sympathetic overdrive in turn is associated with metabolic syndrome, which is a known risk factor for cardiovascular disease. Menopausal hot flushes have a complex relationship to different features of the metabolic syndrome and not all data point towards an association between vasomotor symptoms and metabolic syndrome...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159063/-i-don-t-eat-when-i-m-sick-older-people-s-food-and-mealtime-experiences-in-hospital
#5
Kelti Hope, Maree Ferguson, Dianne P Reidlinger, Ekta Agarwal
BACKGROUND: Inadequate dietary intake is a common problem amongst older acute-care patients and has been identified as an independent risk factor for in-hospital mortality. This study aimed to explore whether food and mealtime experiences contribute to inadequate dietary intake in older people during hospitalisation. METHODS: This was a qualitative phenomenological study, data for which were collected using semi-structured interviews over a three-week period. During this time, 26 patients aged 65 years or more, admitted to medical and surgical wards in a tertiary acute-care hospital, were asked to participate if they were observed to eat less than half of the meal offered at lunch...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159062/abaloparatide-recombinant-human-pthrp-1-34-anabolic-therapy-for-osteoporosis
#6
REVIEW
Chee Kian Chew, Bart L Clarke
The treatment of osteoporosis is generally either by inhibition of bone resorption with antiresorptive agents or by stimulation of bone formation with anabolic agents. Currently, teriparatide (recombinant human parathyroid hormone 1-34 [rhPTH (1-34)]) is the only available approved anabolic agent in the U.S. Other anabolic agents are under investigation however. Abaloparatide is recombinant human parathyroid hormone-related peptide 1-34. This agent is an anabolic agent that appears more potent than teriparatide, and it may have more rapid onset of fracture reduction than teriparatide...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159061/the-effect-of-genistein-on-glucose-control-and-insulin-sensitivity-in-postmenopausal-women-a-meta-analysis
#7
REVIEW
Yang Liu, Jiapeng Li, Tiansheng Wang, Yitong Wang, Libo Zhao, Yi Fang
Preclinical studies have revealed the beneficial effects of genistein in pancreatic β-cell functions. The results of randomized controlled trials (RCTs) in assessing the effects of genistein on glucose metabolism are inconsistent, however. The aim of this meta-analysis is to evaluate the effects of genistein on glucose control and insulin sensitivity in postmenopausal women. This study searched the Medline, PubMed, and Cochrane databases, and ClinicalTrials.gov for trials from January 1970 to February 2016...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159060/gender-differences-in-the-incidence-of-and-risk-factors-for-hip-fracture-a-16-year-longitudinal-study-in-a-southern-european-population
#8
Elena Lobo, Guillermo Marcos, Javier Santabárbara, Helena Salvador-Rosés, Luis Lobo-Escolar, Concepción De la Cámara, Alberto Aso, Antonio Lobo-Escolar
OBJECTIVES: To analyze independently in men and women the incidence rate of and risk factors for hip fracture in a southern European population. Illiteracy, dementia, clinically significant depression and disability were factors to receive special emphasis. STUDY DESIGN: A community sample of 4803 individuals aged over 55 years was assessed in a two-phase case-finding study in Zaragoza, Spain, and was followed up for 16 years. Medical history and psychiatric history were collected with standardized instruments, including the History and Aetiology Schedule, the Geriatric Mental State (GMS) scale, and a Risk Factors Questionnaire...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159059/the-association-between-anorexia-of-aging-and-physical-frailty-results-from-the-national-center-for-geriatrics-and-gerontology-s-study-of-geriatric-syndromes
#9
Kota Tsutsumimoto, Takehiko Doi, Hyuma Makizako, Ryo Hotta, Sho Nakakubo, Keitaro Makino, Takao Suzuki, Hiroyuki Shimada
OBJECTIVES: The present study examined the association between anorexia of aging and physical frailty among older people. STUDY DESIGN: An observational, cross-sectional cohort design was used with a sample of 4417 elderly Japanese citizens living in a community setting. MAIN OUTCOME MEASURES: Frailty was operationalized as the following frailty components: slowness, weakness, exhaustion, low level of physical activity, and weight loss. Participants were grouped as non-frail, pre-frail, and frail, and categorized as anorexic or not using questionnaire cutoff scores...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159058/migraine-and-cardiovascular-disease-in-women
#10
REVIEW
Katie M Linstra, Khatera Ibrahimi, Gisela M Terwindt, Marieke J H Wermer, Antoinette MaassenVanDenBrink
Migraine is responsible for high rates of disability. In addition, it is associated with an increased risk of cardiovascular disease. This association is not limited to the brain in the form of stroke, but includes cardiac ischemia. The increased risk is most consistently described in the female population and in particular for migraine with aura. This article reviews the current knowledge on migraine and the associated risk of cardiovascular disease, with a focus on female-specific factors.
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159057/the-impact-of-parity-and-age-at-first-and-last-childbirth-on-the-prevalence-of-delayed-onset-asthma-in-women-the-korean-national-health-and-nutrition-examination-survey
#11
Ji Ho Choi, Bora Lee, Kyung Do Han, Se Hwan Hwang, Jae Hoon Cho
OBJECT: Asthma is a chronic inflammatory airway disease. The aim of this study was to investigate the relationships between asthma and reproductive factors, including age at first childbirth and parity, in a representative sample of Korean women. MAIN OUTCOME MEASURES: We analyzed data from the Korean National Health and Nutrition Examination Survey (2010-2012). A total of 7837 adults who completed a questionnaire and examination were evaluated. The presence of asthma was based on the Health Interview Survey...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159056/-unknown-title
#12
LETTER
Ekavi Georgousopoulou, Demosthenes B Panagiotakos, Duane Mellor, Nenad Naumovski
No abstract text is available yet for this article.
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159055/design-of-a-frailty-index-among-community-living-middle-aged-and-older-people-the-rotterdam-study
#13
Josje D Schoufour, Nicole S Erler, Loes Jaspers, Jessica C Kiefte-de Jong, Trudy Voortman, Gijsbertus Ziere, Jan Lindemans, Caroline C Klaver, Henning Tiemeier, Bruno Stricker, Arfan M Ikram, Joop S E Laven, Guy G O Brusselle, Fernando Rivadeneira, Oscar H Franco
OBJECTIVES: To design a frailty index (FI) and evaluate three methods to handle missing data. Furthermore, we evaluated its construct (i.e., skewed distribution, correlation with age and sub-maximum score) and criterion validity (based on mortality risk). STUDY DESIGN: We included 11,539 participants (45± years) from a population-based cohort in the Netherlands. Frailty was measured with a FI, which we constructed based on the accumulation of 45 health-related variables, related to mood, cognition, functional status, diseases and conditions, biomarkers, and nutritional status...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28159054/long-term-sequelae-of-unconfined-morcellation-during-laparoscopic-gynecological-surgery
#14
REVIEW
Aviad Cohen, Togas Tulandi
Although rare, unconfined morcellation of occult sarcoma has been associated with reduced survival rates. Morcellation of uterus and myoma can also lead to iatrogenic endometriosis, parasitic myoma and, albeit rarely, disseminated peritoneal leiomyomatosis. These benign sequelae of morcellation occur more often than malignant dissemination of sarcomatous tissue. Accordingly, confined morcellation should be performed with a minimally invasive technique while eliminating tissue dissemination inside the abdominal cavity...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28041602/serum-vitamin-d-and-sex-hormones-levels-in-men-and-women-the-multi-ethnic-study-of-atherosclerosis-mesa
#15
Di Zhao, Pamela Ouyang, Ian H de Boer, Pamela L Lutsey, Youssef M K Farag, Eliseo Guallar, David S Siscovick, Wendy S Post, Rita R Kalyani, Kevin L Billups, Erin D Michos
INTRODUCTION: 25-hydroxyvitamin D [25(OH)D] deficiency has been associated with low testosterone levels in men, but there are conflicting reports of its associations with sex hormones in women. Less is known about whether these associations are independent of adiposity and lifestyle factors, and whether they differ by race/ethnicity. AIM: To examine associations of 25(OH)D concentrations with sex hormone levels. METHODS: Cross-sectional analysis of 3017 men and 2929 women in a multi-ethnic cohort...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041601/higher-intake-of-cryptoxanthin-is-related-to-low-body-mass-index-and-body-fat-in-japanese-middle-aged-women
#16
Asuka Hirose, Masakazu Terauchi, Miho Hirano, Mihoko Akiyoshi, Yoko Owa, Kiyoko Kato, Toshiro Kubota
OBJECTIVES: The prevalence of cardiovascular diseases increases with age, especially in postmenopausal women. In this study, we investigated the dietary patterns associated with body mass and body fat in Japanese middle-aged women. STUDY DESIGN: Cross-sectional. MAIN OUTCOME MEASURES: This study used baseline data collected in a previous study in 88 women aged 40-60 years. Participants were assessed for age, menopausal status, lifestyle factors, body composition, and dietary habits using a brief-type self-administered diet history questionnaire, which provides information on the amounts of nearly 100 nutritional factors consumed during the previous month...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041600/study-protocol-for-the-option-randomised-controlled-trial-on-the-effect-of-prioritising-treatment-goals-among-older-patients-with-cancer-in-a-palliative-setting
#17
M E Stegmann, J Schuling, T J N Hiltermann, A K L Reyners, H Burger, M Y Berger, A J Berendsen
PURPOSE: Traditionally, general practitioners (GPs) are not involved in cancer-related treatment decisions, despite their often long relationship with patients, and their unique position to explore patients' values, especially with older patients. Therefore, we designed a randomised controlled trial to study the effect, on self-efficacy related to treatment decisions, of a conversation about treatment goals between GPs and patients with cancer in a palliative setting. METHODS: We aim to include 168 patients aged ≥70 years with a diagnosis of non-curable cancer, due to consult their oncologist about treatment options...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041599/influence-of-equol-and-resveratrol-supplementation-on-health-related-quality-of-life-in-menopausal-women-a-randomized-placebo-controlled-study
#18
Sergio Davinelli, Giovanni Scapagnini, Fulvio Marzatico, Vincenzo Nobile, Nicola Ferrara, Graziamaria Corbi
OBJECTIVE: This study was designed to evaluate the effects of equol and resveratrol supplementation on health-related quality of life (HRQoL) in otherwise healthy menopausal women with hot flashes, anxiety and depressive symptoms. METHODS: Sixty recently menopausal women aged 50-55 years were randomized in a 12-week, placebo-controlled trial to receive 200mg of fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day). The primary outcome was the change in score on the Menopause Rating Scale (MRS), used to evaluate the severity of age-/menopause-related complaints...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041598/premature-ovarian-insufficiency-and-perinatal-parameters-a-retrospective-case-control-study
#19
S Sadrzadeh, R C Painter, Y M van Kasteren, D D M Braat, C B Lambalk
OBJECTIVE: The peak number of oocytes is reached during intrauterine development, after which numbers decline until reserves are depleted and a woman enters menopause. In premature ovarian insufficiency (POI), the process of follicle depletion occurs at a young age (generally taken as 40 years); the condition affects about 1% of women. In this study, we investigate whether women with POI had experienced a different perinatal milieu, as reflected in their birth weight or prematurity. STUDY DESIGN: In this retrospective case-control study, we evaluated whether women diagnosed with POI had a different birth weight or prematurity rate (<37 weeks) compared with women aged over 40 at natural menopause (the controls)...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28041597/the-effects-of-vitamin-b-on-the-immune-cytokine-network-and-their-involvement-in-depression
#20
REVIEW
Kathleen Mikkelsen, Lily Stojanovska, Monica Prakash, Vasso Apostolopoulos
Increasing evidence indicates that there are various interactions between the nervous system and the immune system, and that the immune system plays an important role in the pathogenesis of depression. Pro-inflammatory cytokines (such as IL-1, IL-6, TNF-α) have been implicated in the neurobiological manifestations of depression. The immune/cytokine network has a powerful influence on the brain. In addition, deficiency in B vitamins has been linked to depression. Hence, greater knowledge of how immune cells change in the presence of vitamin B derivatives could improve understanding of how immune changes may correlate with depression, all of which are discussed herein...
February 2017: Maturitas
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