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Maturitas

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https://www.readbyqxmd.com/read/28381329/implantable-hormonal-contraception-for-women-aged-over-45-years
#1
EDITORIAL
Helen Roberts
No abstract text is available yet for this article.
March 25, 2017: Maturitas
https://www.readbyqxmd.com/read/28396018/urinary-incontinence-and-other-pelvic-floor-disorders-after-radiation-therapy-in-endometrial-cancer-survivors
#2
Saya Segal, Gabriella John, Mary Sammel, Uduak Umoh Andy, Christina Chu, Lily A Arya, Justin Brown, Kathryn Schmitz
OBJECTIVE: To investigate radiation therapy as a risk factor for urinary or fecal incontinence, pelvic organ prolapse, and sexual dysfunction in endometrial cancer survivors. STUDY DESIGN: We performed a retrospective cohort study of endometrial cancer survivors. Data were collected using a mailed survey and the medical record. Validated questionnaires were used to generate rates of urinary incontinence and other pelvic floor disorders. The incidence rates of pelvic floor disorders were compared across groups with different exposures to radiation...
March 18, 2017: Maturitas
https://www.readbyqxmd.com/read/28389043/interventions-to-reduce-the-risk-of-ovarian-and-fallopian-tube-cancer-a-european-menopause-and-andropause-society-postition-statement
#3
REVIEW
Faustino R Pérez-López, Iuliana Ceausu, Herman Depypere, Sean Kehoe, Irene Lambrinoudaki, Alfred Mueck, Levent M Senturk, Tommaso Simoncini, John C Stevenson, Petra Stute, Margaret Rees
BACKGROUND: Ovarian cancer is a leading cause of female gynecological cancer-related death, and there are no effective screening procedures or early diagnostic approaches. AIMS: To examine risk factors and risk-reducing strategies for both sporadic and familial tumors. MATERIALS AND METHODS: Literature review and consensus of expert opinion. RESULTS AND CONCLUSIONS: In women with a genetic predisposition to ovarian cancer, salpingo-oophorectomy reduces the risk of ovarian malignancy, and to a lesser degree of breast cancer...
March 15, 2017: Maturitas
https://www.readbyqxmd.com/read/28320546/a-holistic-approach-to-women-s-health-in-an-ageing-society
#4
EDITORIAL
Manuel Neves-E-Castro
No abstract text is available yet for this article.
February 28, 2017: Maturitas
https://www.readbyqxmd.com/read/28236487/erratum-to-association-of-anthropometric-measures-with-fat-and-fat-free-mass-in-the-elderly-the-rotterdam-study-maturitas-88-2016-96-100
#5
Klodian Dhana, Chantal M Koolhaas, Josje D Schoufour, Fernando Rivadeneira, Albert Hofman, Maryam Kavousi, Oscar H Franco
No abstract text is available yet for this article.
February 21, 2017: Maturitas
https://www.readbyqxmd.com/read/28268037/sexual-health-after-breast-cancer-recommendations-from-the-spanish-menopause-society-federaci%C3%A3-n-espa%C3%A3-ola-de-sociedades-de-sexolog%C3%A3-a-sociedad-espa%C3%A3-ola-de-m%C3%A3-dicos-de-atenci%C3%A3-n-primaria-and-sociedad-espa%C3%A3-ola-de-oncolog%C3%A3-a-m%C3%A3-dica
#6
REVIEW
Nicolás Mendoza, Francisca Molero, Fermín Criado, Mª Jesús Cornellana, Encarna González
Breast cancer is the most common cancer in women. As survival rates are increasing, the long-term health problems of survivors now need attention. Many survivors develop sexual disorders as a consequence of either the side-effects of treatment or induced menopause. A panel of experts from various Spanish scientific societies (Spanish Menopause Society, SMS; Federación Española de Sociedades de Sexología, FESS; Sociedad Española de Médicos de Atención Primaria, SEMERGEN; and Sociedad Española de Oncología Médica) met to develop recommendations for the management of sexual health in breast cancer survivors based on the best evidence available...
February 20, 2017: Maturitas
https://www.readbyqxmd.com/read/28215451/acupuncture-for-the-management-of-menopausal-and-perimenopausal-symptoms-current-clinical-evidence-and-perspectives-for-future-research
#7
EDITORIAL
Tae-Hun Kim, Myeong Soo Lee, Terje Alraek
No abstract text is available yet for this article.
February 7, 2017: Maturitas
https://www.readbyqxmd.com/read/28364876/alterations-of-fatty-acid-profiles-in-gestational-diabetes-and-influence-of-the-diet
#8
REVIEW
Andréa Taschereau-Charron, Marine S Da Silva, Jean-François Bilodeau, Anne-Sophie Morisset, Pierre Julien, Iwona Rudkowska
Gestational diabetes mellitus (GDM) is a pregnancy-induced complication with increased prevalence, especially in overweight women. Fatty acid (FA) composition in tissues can reflect dietary fat intake, especially essential FA intake. Moreover, it has been shown that FA profiles in blood lipid fractions are altered in diabetic patients. Consequently, women with GDM may also have a distinctive FA profile. The objective of this review is compare FA profiles in different blood lipid fractions and the influence of dietary fat intake in women with GDM or normoglycemic pregnancies...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364875/care-homes-the-developing-ideology-of-a-homelike-place-to-live
#9
REVIEW
Anne Fleming, Angela Kydd, Sally Stewart
This paper reports on part of a doctoral study which explored stakeholder perceptions of the importance of a homelike environment in a care home and which factors contributed to this. The changes in institutional care for older people have evolved from being a 'warehouse' type of environment for those too poor, too mad, too sick and too unloved, to a place where older people in need of care can spend their days in safety, in a 'homely' environment. Such an environment is one of the quality indicators of care home provision...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364874/is-the-hymen-a-suitable-cut-off-point-for-clinically-relevant-pelvic-organ-prolapse
#10
Marian Wiegersma, Chantal M C R Panman, Boudewijn J Kollen, Marjolein Y Berger, Yvonne Lisman-van Leeuwen, Janny H Dekker
OBJECTIVES: The primary objective was to evaluate the ability of different anatomic cut-off points, as established in specialist urogynecology populations, to identify clinically relevant prolapse in a population of postmenopausal women with pelvic floor symptoms recruited from primary care. STUDY DESIGN: Cross-sectional study among 890 women (≥55 years) screened for pelvic floor symptoms. MAIN OUTCOME MEASURES: The Pelvic Floor Distress Inventory 20 was used to measure symptoms, and the Pelvic Organ Prolapse Quantification (POP-Q) system was used to assess prolapse...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364873/broadening-our-perspectives-on-complementary-and-alternative-medicine-for-menopause-a-narrative-review
#11
REVIEW
Dunia Tonob, Melissa K Melby
Complementary and alternative medicine (CAM) is widely used for menopause, although not all women disclose use to their healthcare providers. This narrative review aims to expand providers' understanding of cross-cultural approaches to treating and managing menopause by providing an overarching framework and perspective on CAM treatments. Increased provider understanding and awareness may improve not only provider-patient communication but also effectiveness of treatments. The distinction between illness (what patients suffer) and disease (what physicians treat) highlights the gap between what patients seek and doctors provide, and may help clarify why many women seek CAM at menopause...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364872/association-between-pelvic-organ-prolapse-and-climacteric-symptoms-in-postmenopausal-women
#12
Angelo Cagnacci, Federica Palma, Antonella Napolitano, Anjeza Xholli
OBJECTIVE: To evaluate whether climacteric symptoms are related to pelvic organ prolapse (POP) in postmenopausal women. STUDY DESIGN: A cross-sectional investigation was performed on 1382 postmenopausal women attending an outpatient service for menopause at a university hospital. MAIN OUTCOME MEASURES: Data regarding climacteric symptoms, as captured by the Greene Climacteric Scale, and objective POP were retrieved from an electronic database...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364871/oxidative-stress-and-frailty-a-systematic-review-and-synthesis-of-the-best-evidence
#13
REVIEW
Pinar Soysal, Ahmet Turan Isik, Andre F Carvalho, Brisa S Fernandes, Marco Solmi, Patricia Schofield, Nicola Veronese, Brendon Stubbs
OBJECTIVE: Oxidative stress (OS) is associated with accelerated aging. Previous studies have suggested a possible relationship between OS and frailty but this association remains unclear. We conducted a systematic review to investigate potential interactions between OS and frailty. METHODS: A systematic literature search of original reports providing data on 'OS and antioxidant' parameters and frailty was carried out across major electronic databases from inception until May 2016...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364870/plasma-orexin-a-levels-in-recently-menopausal-women-during-and-3-years-following-use-of-hormone-therapy
#14
Dahima Cintron, John P Beckman, Kent R Bailey, Brian D Lahr, Muthuvel Jayachandran, Virginia M Miller
OBJECTIVE: Alterations in sleep quality and metabolism during menopause are improved by menopausal hormone therapy (MHT). The mechanisms mediating these effects remain unclear. Orexin A (OxA) is a neuro-peptide that regulates sleep/wakefulness, food intake and metabolism. This study examined changes in plasma OxA levels during and after treatment in women from the Kronos Early Estrogen Prevention Study (KEEPS). METHODS: KEEPS randomized women within three years of menopause to: oral conjugated equine estrogen (o-CEE, 0...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364869/a-vaginal-estradiol-softgel-capsule-tx-004hr-has-negligible-to-very-low-systemic-absorption-of-estradiol-efficacy-and-pharmacokinetic-data-review
#15
REVIEW
James A Simon, David F Archer, Ginger D Constantine, James H Pickar, Julia M Amadio, Brian Bernick, Shelli Graham, Sebastian Mirkin
This paper reviews the efficacy, safety, and systemic absorption of estradiol with TX-004HR, an investigational, low-dose 17β-estradiol vaginal softgel capsule, designed to treat vulvar and vaginal atrophy (VVA) in postmenopausal women, with an improved user experience. In phase 2 (NCT02449902) and phase 3 REJOICE (NCT02253173) studies, TX-004HR significantly improved the proportions of vaginal superficial and parabasal cells and vaginal pH, and in the phase 3 study decreased the severity of dyspareunia, vaginal dryness, and vulvar and/or vaginal itching or irritation...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364868/sex-differences-in-the-presentation-of-stroke
#16
REVIEW
A Berglund, K Schenck-Gustafsson, M von Euler
Stroke affects both men and women of all ages, although the condition is more common among the elderly. Stroke occurs at an older age among women than among men; although the incidence is lower among women than among men, as women have a longer life expectancy their lifetime risk is slightly higher. Ischemic stroke is the most common type of stroke; and reperfusion treatment is possible if the patient reaches hospital early enough. Thrombolysis and thrombectomy are time-sensitive treatments - the earlier they are initiated the better is the chance of a positive outcome...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364867/preventing-urinary-tract-infections-after-menopause-without-antibiotics
#17
REVIEW
Marta Caretto, Andrea Giannini, Eleonora Russo, Tommaso Simoncini
Urinary tract infections (UTIs) are the most common bacterial infections in women, and increase in incidence after the menopause. It is important to uncover underlying abnormalities or modifiable risk factors. Several risk factors for recurrent UTIs have been identified, including the frequency of sexual intercourse, spermicide use and abnormal pelvic anatomy. In postmenopausal women UTIs often accompany the symptoms and signs of the genitourinary syndrome of menopause (GSM). Antimicrobial prophylaxis has been demonstrated to be effective in reducing the risk of recurrent UTIs in women, but this may lead to drug resistance of both the causative microorganisms and the indigenous flora...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364866/being-overweight-or-obese-is-associated-with-harboring-a-gut-microbial-community-not-capable-of-metabolizing-the-soy-isoflavone-daidzein-to-o-desmethylangolensin-in-peri-and-post-menopausal-women
#18
Lindsey M Miller, Johanna W Lampe, Katherine M Newton, Gabrielle Gundersen, Sharon Fuller, Susan D Reed, Cara L Frankenfeld
OBJECTIVE: Obesity can be a considerable health concern for peri- and post-menopausal women. Evidence suggests an association between the gut microbiome and obesity. The study objective was to evaluate the association between being overweight or obese and phenotypic markers of having an overall gut microbial environment not capable of metabolizing the isoflavone daidzein to equol or O-desmethylangolensin (ODMA). STUDY DESIGN: Cross-sectional study of 137 peri- and 218 post-menopausal women, aged 44-55 years, who consumed at least three servings per week of soy (source of daidzein)...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364865/the-effect-of-hormone-replacement-therapy-and-tibolone-on-lipoprotein-a-concentrations-in-postmenopausal-women-a-systematic-review-and-meta-analysis
#19
REVIEW
Panagiotis Anagnostis, Petros Galanis, Vasileia Chatzistergiou, John C Stevenson, Ian F Godsland, Irene Lambrinoudaki, Mamas Theodorou, Dimitrios G Goulis
OBJECTIVE: Data on the effect of hormone replacement therapy (HRT) and tibolone on lipoprotein (a) [Lp(a)], an independent risk factor for cardiovascular disease, are heterogeneous and conflicting. Studies of the effect of HRT and tibolone on Lp(a) concentrations in post-menopausal women are reviewed in this meta-analysis. DESIGN AND METHODS: MEDLINE, Scopus, EMBASE and Cochrane databases were searched (up to February 10, 2017). Two researchers identified randomized controlled studies and extracted data...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28364864/evaluation-of-the-efficacy-and-safety-of-tribulus-terrestris-in-male-sexual-dysfunction-a-prospective-randomized-double-blind-placebo-controlled-clinical-trial
#20
Zdravko Kamenov, Svetlana Fileva, Krassimir Kalinov, Emmanuele A Jannini
OBJECTIVE: The primary objectives were to compare the efficacy of extracts of the plant Tribulus terrestris (TT; marketed as Tribestan), in comparison with placebo, for the treatment of men with erectile dysfunction (ED) and with or without hypoactive sexual desire disorder (HSDD), as well as to monitor the safety profile of the drug. The secondary objective was to evaluate the level of lipids in blood during treatment. PARTICIPANTS AND DESIGN: Phase IV, prospective, randomized, double-blind, placebo-controlled clinical trial in parallel groups...
May 2017: Maturitas
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