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Irish Journal of Medical Science

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https://www.readbyqxmd.com/read/27882501/a-review-of-a-gp-registrar-run-mobile-health-clinic-for-homeless-people
#1
A O'Carroll, N Irving, J O'Neill, E Flanagan
BACKGROUND: Homeless people have excessively high morbidity and mortality rates, yet they face barriers accessing primary care. A mobile health clinic, staffed by GP registrars, was developed to provide services to homeless people, particularly rough sleepers and sex workers. AIM: The aims were to improve access to primary care and to challenge the stereotypes and prejudices of GP registrars through direct contact with homeless people. DESIGN AND SETTING: This was a qualitative study; questionnaires were completed on the mobile health clinic and two focus groups were conducted...
November 24, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27873142/university-hospital-waterford-5-year-experience-of-cutaneous-melanoma
#2
R Sehgal, C X Cheung, R Alradadi, D A Healy, R Landers, G T O'Donoghue
INTRODUCTION: The incidence of cutaneous melanoma (CM) continues to rise in Ireland. Despite significant advances in melanoma molecular therapy, surgery remains the mainstay of treatment for CM. The University Hospital Waterford (UHW) prospectively maintained CM registry was established in 2010. AIM: To summarize 5-year experience (2010-2015) of primary CM presenting to UHW. METHODS: Data were retrospectively obtained from a central electronic pathology and radiology repository augmented by HIPE data and theatre logs...
November 21, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27864782/the-cost-of-inpatient-management-of-heart-failure-patients-a-microcosting-study-in-the-irish-healthcare-setting
#3
R B Morgan, L McCullagh, M Barry, C Daly
AIMS: To formally assess the resource use and cost of the inpatient treatment of heart failure (HF) from the health-payer's perspective. In addition, to compare costs in our cohort to (a) locally derived patient-level costs (PLC) and (b) national costs as per disease-related group (DRG). METHODS AND RESULTS: Study population Demographics and resource utilisation data were obtained from a cohort of 30 patients (57% male, mean age 70 years) admitted into a single tertiary centre with heart failure...
November 19, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27844336/radiation-safety-awareness-among-medical-interns-are-eu-guidelines-being-implemented
#4
A M Lee, M J Lee
BACKGROUND: European recommendations suggest that medical students should be taught radiation safety before entering clinical practice. AIM: The aim of this study was to produce a summative assessment of radiation protection training in medical school in Ireland. MATERIALS AND METHODS: A web-based questionnaire was distributed to the 2014 intern population (n = 683) via network intern-coordinators. The survey encompassed knowledge of radiation dose in X-ray investigations, laws governing the prescribing of radiation and complications of radiation exposure to staff and patients...
November 14, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27830442/venous-thromboembolism-prophylaxis-risk-assessment-in-a-general-surgery-cohort-a-closed-loop-audit
#5
D M McGoldrick, H P Redmond
BACKGROUND AND AIMS: Venous thromboembolism (VTE) is a potential source of morbidity and mortality in surgical in-patients. A number of guidelines exist that advise on prophylactic measures. We aimed to assess VTE prophylaxis prescribing practices and compliance with a kardex-based risk assessment tool in a general surgery population. METHODS: Data on general surgery in-patients were collected on two separate wards on two separate days. Drug kardexes were assessed for VTE prophylaxis measures and use of the risk assessment tool...
November 9, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27822908/the-duration-of-gonadotropin-stimulation-does-not-alter-the-clinical-pregnancy-rate-in-ivf-or-icsi-cycles
#6
N Purandare, G Emerson, C Kirkham, C Harrity, D Walsh, E Mocanu
BACKGROUND: Ovarian stimulation is an essential part of assisted reproduction treatments. Research on whether the duration of stimulation alters the success in assisted reproduction has not been conclusive. AIM: The purpose of the study was to establish whether the duration of ovarian stimulation alters the success in assisted reproduction treatments. METHODS: All fresh (non-donor) stimulation cycles performed in an academic tertiary referral ART centre over a period of 18 years, between 1st January 1997 and 31st December 2014, were identified...
November 7, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27822907/multiple-intra-hospital-transports-during-relocation-to-a-new-critical-care-unit
#7
R-A O'Leary, I Conrick-Martin, C O'Loughlin, M-R Curran, B Marsh
OBJECTIVE: Intra-hospital transport (IHT) of critically ill patients is associated with morbidity and mortality. Mass transfer of patients, as happens with unit relocation, is poorly described. We outline the process and adverse events associated with the relocation of a critical care unit. DESIGN: Extensive planning of the relocation targeted patient and equipment transfer, reduction in clinical pressure prior to the event and patient care during the relocation phase...
November 7, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27817165/obesity-is-not-a-descriptive-factor-for-oxidative-stress-and-viscosity-in-follicular-fluid-of-in-vitro-fertilization-patients
#8
B Yuksel, S Kilic, N Yilmaz, T Goktas, U Keskin, A Seven, M Ulubay, S Batioglu
BACKGROUND: Obesity's impact on micro-environmental oxidative stress and follicular fluid (FF) viscosity and whether or not it has any effect on in vitro fertilization (IVF) success is a matter of debate. AIMS: In this study, our aim was to evaluate the levels of oxidative stress markers and the FF viscosity in obese and non-obese patients. METHODS: Eighty norm-responder patients undergoing IVF were prospectively grouped according to their body mass indexes (BMI)...
November 5, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27804078/assessment-of-the-2d-4d-ratio-in-aggression-related-injuries-in-children-attending-a-paediatric-emergency-department
#9
D E O'Briain, P H Dawson, J C Kelly, P Connolly
BACKGROUND: The 2D:4D ratio is a sexually dimorphic trait. A lower ratio is correlated with sporting prowess, successful financial trading, risk taking behaviour, aggression, and aggression-related injuries, such as the fifth metacarpal fractures. AIMS: We aimed to assess if the ratio correlates to skeletally immature patient aggression. METHODS: Radiology reports were searched for the terms "5th metacarpal" or "boxer". Of 537 X-rays, 142 had fractures...
November 1, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27796667/lymphocyte-integrin-expression-differences-between-sirs-and-sepsis-patients
#10
D S Heffernan, S F Monaghan, Alfred Ayala
BACKGROUND: Systemic Inflammatory Response Syndrome (SIRS) and sepsis remain leading causes of death. Despite many similarities, the two entities are very distinct clinically and immunologically. T-Lymphocytes play a key pivotal role in the pathogenesis and ultimately outcome following both SIRS and sepsis. Integrins are essential in the trafficking and migration of lymphocytes. They also serve vital roles in efficient wound healing and clearance of infections. Here, we investigate whether integrin expression, specifically β1 (CD29) and β2 (CD18), are disrupted in SIRS and sepsis, and assess differences in integrin expression between these two critically ill clinical categories...
October 31, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27796666/effects-of-remote-ischemic-preconditioning-on-acute-myocardial-injury-in-patients-undergoing-valve-replacement
#11
Z Cao, R Shen, X Zhang, G Cheng, Z Yan
BACKGROUND: This study investigated the effects of remote ischemic preconditioning (RIPC) on acute myocardial injury and clinical outcome in adult patients undergoing valve replacement surgery. METHODS: Sixty-three adult patients scheduled for elective valve replacement undergoing cardiopulmonary bypass (CPB) were randomly assigned to control or remote ischemic preconditioning treatment. RIPC was applied beginning with the first surgical incision by three times of inflating the cuff to 200 mmHg for 5 min, followed by 5 min of deflation...
October 31, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27796665/patient-reported-functional-outcomes-following-robotic-assisted-rarp-laparoscopic-lrp-and-open-radical-prostatectomies-orp
#12
G J Nason, F O'Kelly, S White, E Dunne, G P Smyth, R E Power
BACKGROUND: Radical prostatectomy for prostate cancer is associated with significant complications, such as urinary incontinence and erectile dysfunction. Debate remains regarding the influence of surgical technique on these important functional outcomes. AIM: The aim of this study was to compare the early functional outcomes following robotic-assisted (RARP), laparoscopic (LRP), and open radical prostatectomy (ORP) in a rapid access cohort. METHODS: A retrospective review of a prospectively maintained database was performed between 2011 and 2014...
October 28, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27770264/the-benefits-of-utilising-geo-mapping-for-visualising-the-vitamin-d-status-of-dublin-city-and-the-surrounding-urban-districts
#13
E Laird, T Shannon, V E F Crowley, M Healy
CONTEXT: There have been few published reports of visualising vitamin D status at a micro level, i.e., within large individual urban centres of countries. OBJECTIVE: To produce a visual map of the vitamin D status [25-hydroxy vitamin D-25(OH)D] of a large urban centre (n > 350,000) incorporating the regions of Dublin city that constitute the general practitioner catchment area of a large academic teaching adult hospital. DESIGN, SETTING AND PARTICIPANTS: An observational investigation of 5287 free living Irish adults (>18 years)...
October 21, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27757731/the-new-system-of-health-accounts-in-ireland-what-does-it-all-mean
#14
B Turner
BACKGROUND: The Central Statistics Office released new figures on Ireland's health spending in December 2015, based on the System of Health Accounts (SHA2011). These figures differ from previous figures, by virtue of an expanded definition of what constitutes health care. The new figures also provide more detail on health expenditure than the previous figures allowed. AIMS: This article examines the new figures, drawing out findings of note and discussing the implications of these for the Irish health care system...
October 18, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27752924/colorectal-cancer-incidence-and-survival-by-sub-site-and-stage-of-diagnosis-a-population-based-study-at-the-advent-of-national-screening
#15
J McDevitt, H Comber, P M Walsh
BACKGROUND: The location and staging of a colorectal cancer (CRC) determine prognosis and choice of treatment. We examined the sub-site, sex, and stage distribution for CRC in Ireland for patients diagnosed in the period immediately prior to the implementation of a national screening programme. METHODS: Incident cases of CRC were abstracted from the National Cancer Registry for the period 1994-2012 (n = 38,912). Incidence proportions and 3-year cancer-related survival were calculated...
October 18, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27744643/proton-therapy-in-paediatric-oncology-an-irish-perspective
#16
K A Lee, C O'Sullivan, P Daly, J Pears, C Owens, B Timmermann, C Ares, S E Combs, D Indelicato, M Capra
BACKGROUND: Proton therapy (PT) is a radiotherapy treatment modality that uses protons, rather than conventional photons. PT is often used in paediatric oncology due to its reported capability to reduce acute and late adverse treatment effects. As PT is unavailable in Ireland, patients are referred abroad for treatment. AIMS: To: (1) produce a descriptive study of Irish children referred abroad for PT, and (2) discuss the case for PT in general. METHODS: A retrospective review of all children referred for PT before October 2015 was performed...
October 15, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27744642/a-decade-of-domiciliary-non-invasive-ventilation-in-the-west-of-ireland
#17
P Gouda, J Chua, D Langan, T Hannon, A Scott, A O'Regan
BACKGROUND: While domiciliary non-invasive ventilation (NIV) was initially used in the treatment of respiratory failure resulting from chest wall deformity, the main indication is now chronic obstructive pulmonary disease (COPD) with recurrent exacerbations associated with type 2 respiratory failure. A longitudinal study of domiciliary NIV provides insights into the evolution of this treatment in the west of Ireland. METHODS: The cohort of patients receiving new prescriptions for domiciliary NIV from Galway University Hospital from 2000 to 2012 was reviewed using study coordinator chart reviews and telephone follow-ups...
October 15, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27734241/the-influence-of-breast-cancer-subtype-on-bone-metastases-development-and-survival-in-women-with-metastatic-breast-cancer
#18
R P Piggott, P S Waters, M J Kerin
BACKGROUND: Tumour metastatic disease reflects a complex interplay between tumour characteristics and local host factors. This complex relationship may have an influence on the development of metastatic disease and patient survival. Multiple factors of the primary tumour influence the development of metastases and survival in patients. Breast cancer subtype has been shown to influence patient prognosis and response to therapy. AIM: The aim of our study was to correlate breast cancer subtype with bony metastatic disease and patient survival...
October 12, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27730333/characterization-of-patients-with-diabetic-foot-disease-presenting-to-an-irish-podiatry-centre-profiling-suitability-for-entry-to-a-clinical-trial-of-advanced-wound-therapeutics
#19
A M Mahon, C MacGilchrist, C McIntosh, T O'Brien
BACKGROUND: Diabetes mellitus, coined the 'Black Death of the Twenty-First Century', is associated with complications, including foot ulceration with potential loss of limb. There is a need for development of new wound therapies through completion of robust clinical trials. AIMS: To profile demographics and wound characteristics of an Irish cohort with diabetes, forecast eligibility for entry to a clinical trial of advanced wound therapeutics, and adjust criteria to optimize eligibility for enrolment...
October 11, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27730332/pregnancy-associated-plasma-protein-a-papp-a-as-a-possible-biomarker-in-patients-with-coronary-artery-disease
#20
H Gutiérrez-Leonard, E Martínez-Lara, A E Fierro-Macías, V M Mena-Burciaga, M D Ronquillo-Sánchez, E Floriano-Sánchez, N Cárdenas-Rodríguez
BACKGROUND: Cardiovascular disease is the leading cause of death in the Western world, and a major cause of this disease is atherosclerosis. Research has demonstrated that pregnancy-associated plasma protein A (PAPP-A) plays a role in cardiovascular disease, as evidenced by the association between PAPP-A and severity of heart damage. AIM: The aim of this work was to investigate the correlation between PAPP-A concentrations in coronary and peripheral blood and certain clinicopathological factors and antioxidant enzyme activities in patients diagnosed with coronary artery disease...
October 11, 2016: Irish Journal of Medical Science
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