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JPEN. Journal of Parenteral and Enteral Nutrition

Tarifin Sikder, Geva Maimon, Nadia Sourial, Mehdi Tahiri, Debby Teasdale, Paule Bernier, Shannon A Fraser, Sebastian Demyttenaere, Simon Bergman
BACKGROUND: Malnutrition among elderly surgical patients has been associated with poor postoperative outcomes and reduced functional status. Although previous studies have shown that nutrition contributes to patient outcomes, its long-term impact on functional status requires better characterization. This study examines the effect of nutrition on postoperative upper body function over time in elderly patients undergoing elective surgery. METHODS: This is a 2-year prospective study of elderly patients (≥70 years) undergoing elective abdominal surgery...
April 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Manpreet S Mundi, Wanda Duellman, Lisa Epp, Jacob Davidson, Ryan T Hurt
BACKGROUND: Misconnections between enteral supplies and other access devices have led to significant morbidity and mortality. To reduce misconnections, a standard small-bore connector has been developed (International Organization for Standards 80369-8; ENFit). The full impact of transition to this connector is not known, however. METHOD: Working with major manufacturers and Food and Drug Administration, we obtained ENFit and comparative legacy tubes of variable sizes (low-profile, 14F, 18F, 20F, and 24F balloon gastrostomies)...
April 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Giliane Belarmino, Maria Cristina Gonzalez, Priscila Sala, Raquel Susana Torrinhas, Wellington Andraus, Luiz Augusto Carneiro D'Albuquerque, Rosa Maria R Pereira, Valéria F Caparbo, Eduardo Ferrioli, Karina Pfrimer, Lucas Damiani, Steven B Heymsfield, Dan L Waitzberg
BACKGROUND: Ascites in cirrhotic patients interfere with accurate assessment of skeletal muscle when diagnosing sarcopenia. We hypothesized measurement of appendicular skeletal muscle index (ASMI) with dual-energy x-ray absorptiometry (DXA) improves the diagnosis of sarcopenia in cirrhotic patients as ASMI does not include the fluid-filled abdominal compartment. OBJECTIVE: To evaluate if ASMI is influenced by ascites, lower limb edema (LLE) and predicts mortality alone or combined with handgrip strength (HGS) in cirrhotic patients...
April 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Pierre Poinsot, Perrine Geoffroy, Pierre Braillon, Angelique Denis, Irene Loras-Duclaux, Stéphanie Marotte, Stéphanie Boutroy, Justine Bacchetta, Sandrine Touzet, Alain Lachaux, Noel Peretti
BACKGROUND: Metabolic bone disease is common in children receiving home parenteral nutrition (HPN) for intestinal failure (IF). Long-term evolution of bone mass in pediatric IF is poorly documented. The aims of this study were (1) to determine the prevalence of low bone mass (LBM) in children receiving HPN for IF, (2) to evaluate the evolution of total bone mineral content (TBMC) during HPN with dual-energy x-ray absorptiometry (DXA), and (3) to identify related factors. METHODS: All children referred in our HPN center from 2004 to 2014 were eligible...
March 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Heidi Zweers, Mirian C H Janssen, Susanne Leij, Geert Wanten
BACKGROUND: Mitochondrial disease (MD) is a group of disorders caused by dysfunctional mitochondria, the organelles that generate energy for the cell. Malnutrition in patients with MD may lead to increased mitochondrial dysfunction, which may enhance already existing symptoms. The aim of this study was to investigate whether patients with MD have an insufficient or unbalanced food intake and to establish which nutrients and product groups are particularly compromised in this patient group...
March 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Carmen A Cunningham, Lindsay B Gervais, Vera C Mazurak, Vijay Anand, Daniel Garros, Katelynn Crick, Bodil M K Larsen
BACKGROUND: Patients admitted to pediatric intensive care units (PICUs) often experience prolonged periods without nutrition support, which may result in hospital-induced malnutrition and longer length of stay. Nurse-driven feeding protocols have been developed to prevent unnecessary interruptions or delays to nutrition support. The primary objective of this study was to identify compliance and reasons for noncompliance to a feeding protocol at a tertiary care hospital PICU in Canada...
February 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Patricia Worthington, Jane Balint, Matthew Bechtold, Angela Bingham, Lingtak-Neander Chan, Sharon Durfee, Andrea K Jevenn, Ainsley Malone, Maria Mascarenhas, Daniel T Robinson, Beverly Holcombe
Parenteral nutrition (PN) represents one of the most notable achievements of modern medicine, serving as a therapeutic modality for all age groups across the healthcare continuum. PN offers a life-sustaining option when intestinal failure prevents adequate oral or enteral nutrition. However, providing nutrients by vein is an expensive form of nutrition support, and serious adverse events can occur. In an effort to provide clinical guidance regarding PN therapy, the Board of Directors of the American Society for Parenteral and Enteral Nutrition (ASPEN) convened a task force to develop consensus recommendations regarding appropriate PN use...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Tommy Cederholm, Gordon L Jensen
During the European Society for Clinical Nutrition and Metabolism (ESPEN) Congress in Copenhagen, Denmark (September 2016), representatives of the 4 largest global parenteral and enteral nutrition (PEN) societies from Europe (ESPEN), the United States (American Society for Parenteral and Enteral Nutrition [ASPEN]), Asia (Parenteral and Enteral Nutrition Society of Asia [PENSA]), and Latin America (Latin American Federation of Parenteral and Enteral Nutrition [FELANPE]) and from national PEN societies around the world met to continue the conversation on how to diagnose malnutrition that started during the Clinical Nutrition Week, Austin, Texas (February 2016)...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Ronald L Koretz
No abstract text is available yet for this article.
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
(no author information available yet)
Boullata JI, Carrera AL, Harvey L, et al. ASPEN safe practices for enteral nutrition therapy. JPEN J Parenter Enteral Nutr. 2017;41:15-103. (Original DOI: 10.1177/0148607116673053 ).
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
(no author information available yet)
White JV, Guenter P, Jensen G, et al. CONSENSUS STATEMENT: Academy of Nutrition and Dietetics and American Society for Parenteral and Enteral Nutrition: characteristics recommended for the identification and documentation of adult malnutrition (undernutrition). JPEN J Parenter Enteral Nutr. 2012;36:275-283. (Original DOI: 10.1177/0148607112440285 ).
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Krishnan Sriram, Suela Sulo, Gretchen VanDerBosch, Jamie Partridge, Josh Feldstein, Refaat A Hegazi, Wm Thomas Summerfelt
BACKGROUND: Although screening patients for malnutrition risk on hospital admission is standard of care, nutrition shortfalls are undertreated. Nutrition interventions can improve outcomes. We tested effects of a nutrition-focused quality improvement program (QIP) on hospital readmission and length of stay (LOS). MATERIALS AND METHODS: QIP included malnutrition risk screening at admission, prompt initiation of oral nutrition supplements (ONS) for at-risk patients, and nutrition support...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Ronald L Koretz, Timothy O Lipman
Systematic reviews should be distinguished from narrative reviews. In the latter, an editor asks an expert to sum up all of the information that is known about a particular topic. However, the expert is under no constraints regarding what he or she does, or does not, choose to include in the review. As a result, his or her bias can influence the final message. A systematic review, which may or may not be written by experts, typically asks a narrower question, and then answers it using the entirety of the medical literature...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Neil Grenade, Christina Kosar, Karen Steinberg, Yaron Avitzur, Paul W Wales, Glenda Courtney-Martin
Vitamin D deficiency is common in patients with intestinal failure and short bowel syndrome who have been weaned of parenteral nutrition. Dietary supplementation with vitamin D is necessary to correct this deficiency. In certain cases, routine supplementation strategy may be ineffective. We report 3 cases of vitamin D deficiency in patients with intestinal failure who showed improvement in serum 25-hydroxyvitamin D levels after supplementation with a loading dose of 20,000-40,000 IU vitamin D provided weekly...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Moftah H Alhagamhmad, Andrew S Day, Daniel A Lemberg, Steven T Leach
BACKGROUND: Exclusive enteral nutrition (EEN) therapy using a polymeric formula (PF) can substantially attenuate intestinal inflammation in Crohn's disease (CD) patients. However, the mechanism(s) by which EEN suppresses inflammation are not yet fully understood. The aims were to examine cellular mechanism(s) through which EEN may suppress inflammation and investigate potential pathways to enhance anti-inflammatory properties of EEN. METHODS: Glutamine, arginine, vitamin D3, and α linolenic acid (ALA), present in PF, along with curcumin, were identified as immunoactive nutrient therapies...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Philippe Chessex, Sophie Laborie, Nehad Nasef, Benoit Masse, Jean-Claude Lavoie
BACKGROUND: Intravenous nutrition preparations that are not photoprotected generate oxidants, which are deleterious for cell survival. The question remains: are these observations of clinical relevance in individuals receiving parenteral nutrition (PN), especially in those who exhibit immature antioxidant defenses such as premature infants? OBJECTIVE: To review clinical trials reporting the effect of light-exposed vs light-protected PN to determine whether photoprotection reduces neonatal mortality in preterm infants...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Kathy Prelack, Yong Ming Yu, Maggie Dylewski, Martha Lydon, Timothy J Keaney, Robert L Sheridan
BACKGROUND: A persistent hypermetabolic state delays anabolism and growth in burned children. However, our own clinical experience has been that resting energy expenditure (REE) is not increased during the rehabilitative phase, suggesting other contributing factors. We measured total energy expenditure (TEE) and its components in rehabilitating pediatric burn patients to identify the basis for accelerated energy metabolism in this population. MATERIALS AND METHODS: Children admitted with initial burns of 20% of their total body surface area (TBSA) or greater were enrolled into this prospective, descriptive study...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Ali Arshad, John Isherwood, Christopher Mann, Jill Cooke, Cristina Pollard, Franscois Runau, Bruno Morgan, William Steward, Matthew Metcalfe, Ashley Dennison
BACKGROUND: Marine-derived ω-3 fatty acids (ω-3FAs) have proven antitumor activity in vivo and in vitro and improve quality of life (QOL) in clinical cancer studies. These changes may be mediated by reduction in circulating proangiogenic and proinflammatory factors. In this first study of intravenous ω-3FAs as a therapy in cancer patients, we aimed to assess if it could augment the antitumor activity of gemcitabine in patients with advanced pancreatic cancer and improve QOL. MATERIALS AND METHODS: Patients were administered gemcitabine 1000 mg/m(3) weekly followed by up to 100 g (200 mg/mL) of ω-3 rich lipid emulsion for 3 weeks followed by a rest week...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Lauren M Beckman, Joseph I Boullata, Paige L Fisher, Charlene W Compher, Carrie P Earthman
BACKGROUND: When managing patients with disorders that require clinical intervention, a practical assessment of body habitus is valued. The Duffull-Green lean body weight (LBW) equation was derived and validated in adults across a wide body mass index (BMI) range. Whether this predictive equation will perform well in patients at BMI extremes or perform better than a widely used empiric "ideal" body weight (IBW) equation is unknown. MATERIALS AND METHODS: Calculated LBW and calculated IBW were each compared with the dual-energy x-ray absorptiometry (DXA)-derived lean body mass (LBM) by simple linear regression...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
Andrea Carpenter, Vicky Lee Ng, Karen Chapman, Simon C Ling, Marialena Mouzaki
BACKGROUND AND OBJECTIVES: Malnutrition is common in children with end-stage liver disease (ESLD) and is associated with increased morbidity and mortality. The inability to accurately estimate energy needs of these patients may contribute to their poor nutrition status. In clinical practice, predictive equations are used to calculate resting energy expenditure (cREE). The objective of this study is to assess the accuracy of commonly used equations in pediatric patients with ESLD. METHODS: Retrospective study performed at the Hospital for Sick Children...
March 2017: JPEN. Journal of Parenteral and Enteral Nutrition
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