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JPEN. Journal of Parenteral and Enteral Nutrition

Ronald L Koretz
No abstract text is available yet for this article.
January 15, 2019: JPEN. Journal of Parenteral and Enteral Nutrition
Danielle McClanahan, Andrew Yeh, Brian Firek, Stacey Zettle, Matthew Rogers, Richard Cheek, Michelle V L Nguyen, Christopher P Gayer, Stacy G Wendell, Steven J Mullett, Michael J Morowitz
BACKGROUND: Dietary intake sharply impacts the structure and function of the gut microbiota, which is important for childhood health. However, little is known about the microbiota of children who cannot eat by mouth. Standard enteral formulas for supplemental nutrition are low in fiber and high in processed sugars and are commonly associated with gastrointestinal side effects. In this pilot study, we examined the effects of plant-based enteral nutrition (PBEN) upon the gut bacteria of chronically ill children...
January 15, 2019: JPEN. Journal of Parenteral and Enteral Nutrition
George M Slim, Marihan Lansing, Pamela Wizzard, Patrick N Nation, Sarah E Wheeler, Patricia L Brubaker, Palle B Jeppesen, Paul W Wales, Justine M Turner
BACKGROUND: Glucagon-like peptide-2 (GLP-2) is an intestinotrophic factor released from L-cells in the ileum, a segment commonly resected or atretic in neonatal short bowel syndrome (SBS). In piglets, ileal resection decreases intestinal adaptation and endogenous GLP-2 production, whereas exogenous replacement promotes adaptation. In this study, we determined the effect of a novel long-acting GLP-2 analogue, FE 203799 (FE; apraglutide), upon intestinal growth, adaptation, and function in neonatal SBS piglets without ileum...
January 6, 2019: JPEN. Journal of Parenteral and Enteral Nutrition
Mariela Bernabe-García, Raúl Villegas-Silva, Astrid Villavicencio-Torres, Philip C Calder, Maricela Rodríguez-Cruz, Jorge Maldonado-Hernández, Denisse Macías-Loaiza, Mardia López-Alarcón, Patricia Inda-Icaza, Leonardo Cruz-Reynoso
BACKGROUND: Retinopathy of prematurity (ROP) is a disorder of the retina of low-birth-weight preterm infants that potentially leads to blindness. Docosahexaenoic acid (DHA), is protective in experimental models, but its administration as part of parenteral nutrition has shown inconsistent results. We test the effect of enteral DHA to prevent ROP and/or severity and to reduce hospital stay. METHODS: This was a double-blind parallel clinical trial. Preterm infants (n = 110; 55 per group) with birth weight <1500 g but ≥1000 g were recruited in a neonatal intensive care unit...
January 6, 2019: JPEN. Journal of Parenteral and Enteral Nutrition
Lucy Perrem, Jana Semberova, Anne O'Sullivan, Emily A Kieran, Colm P F O'Donnell, Martin John White, Jan Miletin
BACKGROUND: Peripherally inserted central catheters (PICCs) are used to administer parenteral nutrition (PN) in very low birth weight infants (VLBW; <1500 g). Clinicians try to optimize early nutrition but also minimize the risks associated with intravascular devices. The objective of this study was to examine the early nutrition impact of discontinuing PN at different enteral feed volumes in VLBW infants. METHODS: In this unmasked, multicenter, randomized controlled trial, patients were randomly assigned to PICC removal and PN discontinuation at an enteral feed volume of 100 mL/kg/day (intervention) or 140 mL/kg/day (control)...
January 6, 2019: JPEN. Journal of Parenteral and Enteral Nutrition
Dandan Zhang, Jie Wen, Jiefei Zhou, Wei Cai, Linxi Qian
BACKGROUND: Evidence has provided support for the beneficial effects of milk fat globule membrane (MFGM) on inflammation in the intestinal tract. The objective of this study was to investigate the effects of MFGM on a rat model of necrotizing enterocolitis (NEC) and its potential mechanism of action. METHODS: Sixty-two newborn Sprague Dawley rats were randomly divided into 4 experimental groups: Breast-fed normal, formula fed (FF), FF + 6 g/L MFGM, and FF + 12 g/L MFGM...
January 6, 2019: JPEN. Journal of Parenteral and Enteral Nutrition
Lyvonne N Tume, Frédéric V Valla, Alejandro A Floh, Praveen Goday, Corinne Jotterand Chaparro, Bodil Larsen, Jan Hau Lee, Yara M F Moreno, Nazima Pathan, Sascha Verbruggen, Nilesh M Mehta
BACKGROUND: Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations. OBJECTIVE: The objective of this paper was to develop a list of topics to be prioritized for nutrition research in pediatric critical care in the next 10 years. METHODS: A modified 3-round Delphi process was undertaken by a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition...
December 26, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Helen Lowe, Stacey Segal, Marialena Mouzaki, Veronika Langos, Nomazulu Dlamini
No abstract text is available yet for this article.
December 20, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Ann-Marie Brown, Elaine Fisher, Michael L Forbes
BACKGROUND: Malnutrition increases the risk of mortality and morbidity in the pediatric intensive care unit (PICU). Barriers to adequate delivery of enteral nutrition (EN) include hemodynamic instability, feeding interruptions and intolerance, and lack of standardized feeding protocols. The most recent guidelines on nutrition support for the critically ill child describe a paucity of evidence around the best method to deliver EN. There is an untested clinical assumption that bolus gastric feeding (B-GF) in intubated patients is associated with aspiration events, lung injury, and associated morbidity compared with continuous gastric feeding (C-GF)...
December 20, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Andrew S Tseng, Nicole A Traub, Lucinda A Harris, Michael D Crowell, Charlene R Hoffman-Snyder, Brent P Goodman, John K DiBaise
BACKGROUND: Patients with postural tachycardia syndrome (POTS) often have gastrointestinal (GI) symptoms. Occasionally, these symptoms can be so severe that nonoral nutrition/hydration support (NONHS), including intravenous fluids (IVFs), enteral nutrition (EN), and parenteral nutrition (PN), becomes necessary. METHODS: This is a retrospective cohort study of adult patients diagnosed with POTS at the Mayo Clinic Arizona from January 2010 to January 2017 with a minimum of 6 months of follow up...
December 18, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Erin F Barreto, Tejaswi Kanderi, Sara R DiCecco, Arnaldo Lopez-Ruiz, Janelle O Poyant, Kristin C Mara, Joy Heimgartner, Ognjen Gajic, Andrew D Rule, Erin M Nystrom, Kianoush B Kashani
BACKGROUND: Reliable and valid tools to screen for malnutrition in the intensive care unit (ICU) remain elusive. The sarcopenia index (SI) [(serum creatinine/serum cystatin C) × 100], could be an inexpensive, objective tool to predict malnutrition. We evaluated the SI as a screening tool for malnutrition in the ICU and compared it with the modified-NUTRIC score. MATERIALS AND METHODS: This was a historical cohort study of ICU patients with stable kidney function admitted to Mayo Clinic ICUs between 2008 and 2015...
December 18, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Korn Lertpipopmetha, Chanon Kongkamol, Pimsiri Sripongpun
BACKGROUND: Diarrhea in enteral tube-fed patients is not uncommon and can lead to unfavorable outcomes. Fiber in enteral nutrition (EN) formula might play a role in postfeeding diarrhea. Theoretically, soluble fiber is beneficial for both prevention and treatment of postfeeding diarrhea, but different types of soluble fiber may not provide the same effect. This study aims to determine whether supplementation with psyllium in standard EN reduces the incidence of diarrhea in tube-fed patients...
December 18, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
David A August
No abstract text is available yet for this article.
December 18, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Farrukh R Virani, Travis Peery, Orlyn Rivas, Jeffrey Tomasek, Ravin Huerta, Charles E Wade, Jenny Lee, John B Holcomb, Karen Uray
BACKGROUND: Although feeding intolerance is a common complication in trauma patients, the incidence, development, and effects are poorly understood. METHODS: We performed a retrospective study in which trauma patients were classified as having feeding intolerance based on time to reach feeding goal. Subsequently, we sorted patients by gastric residual volumes (GRVs) or symptoms of slowed gastrointestinal motility. RESULTS: One-third of trauma patients experienced delayed time to reach feeding goal after diet initiation...
December 3, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Christian Stoppe, Julia Ney, Vladimir V Lomivorotov, Sergey M Efremov, Carina Benstoem, Aileen Hill, Ekaterina Nesterova, Elena Laaf, Andreas Goetzenich, Bernard McDonald, Arne Peine, Gernot Marx, Karl Fehnle, Daren K Heyland
BACKGROUND: Cardiovascular surgery patients with a prolonged intensive care unit (ICU) stay may benefit most from early nutrition support. Using established scoring systems for nutrition assessment and operative risk stratification, we aimed to develop a model to predict a prolonged ICU stay ≥5 days in order to identify patients who will benefit from early nutrition interventions. METHODS: This is a retrospective analysis of a prospective observational study of patients undergoing elective valvular, coronary artery bypass grafting, or combined cardiac surgery...
December 2, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
David A August
No abstract text is available yet for this article.
November 29, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Brett R Loman, Menghua Luo, Geraldine E Baggs, Diane C Mitchell, Jeffrey L Nelson, Thomas R Ziegler, Nicolaas E Deutz, Laura E Matarese
BACKGROUND: Reduced nutrient intake is common in patients after hospitalization, contributing to increased risk for readmission and mortality. Oral nutrition supplements can improve nutrition status and clinical outcomes, but intake of food is prioritized by clinicians. This study examines the impact of a high-protein oral nutrition supplement (S-ONS) on nutrient intake post discharge. METHODS: In a subset of patients (14 S-ONS and 16 placebo) from the NOURISH (Nutrition effect On Unplanned ReadmIssions and Survival in Hospitalized patients) trial, 24-hour dietary recalls were conducted on 3 randomly selected days during the weeks of 30, 60, and 90 days post discharge...
November 22, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Marita de Waard, Yanqi Li, Yanna Zhu, Adejumoke I Ayede, Janet Berrington, Frank H Bloomfield, Olubunmi O Busari, Barbara E Cormack, Nicholas D Embleton, Johannes B van Goudoever, Gorm Greisen, Zhongqian He, Yan Huang, Xiaodong Li, Hung-Chih Lin, Jiaping Mei, Paula P Meier, Chuan Nie, Aloka L Patel, Christian Ritz, Per T Sangild, Thomas Skeath, Karen Simmer, Olukemi O Tongo, Signe S Uhlenfeldt, Sufen Ye, Xuqiang Ye, Chunyi Zhang, Ping Zhou
BACKGROUND: Transition to enteral feeding is difficult for very low-birth-weight (VLBW; ≤1500 g) infants, and optimal nutrition is important for clinical outcomes. METHOD: Data on feeding practices and short-term clinical outcomes (growth, necrotizing enterocolitis [NEC], mortality) in VLBW infants were collected from 13 neonatal intensive care units (NICUs) in 5 continents (n = 2947). Specifically, 5 NICUs in Guangdong province in China (GD), mainly using formula feeding and slow feeding advancement (n = 1366), were compared with the remaining NICUs (non-GD, n = 1581, Oceania, Europe, United States, Taiwan, Africa) using mainly human milk with faster advancement rates...
November 22, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
David C Frankenfield
BACKGROUND: Predicting resting metabolic rate (RMR) in mechanically ventilated, critically ill patients is an important part of the nutrition care in such patients. METHODS: RMR and associated clinical data from various studies of mechanically ventilated, critically ill patients were combined, and the impact of body size, age, reason for admission, and sedation level were analyzed along with prediction methods of RMR (the American Society for Parenteral and Enteral Nutrition [ASPEN] standards and the Penn State equation)...
November 21, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Min Yang, Meizhen Tan, Jieling Wu, Zhuojie Chen, Xiaoling Long, Yongmei Zeng, Huabo Cai, Yong Zhang, Lanlan Geng, Yulian Xiao, Haijin Ke, Ying Liu, Linhui Rong, Simao Fu, Hong Wang, Yuan Wang, Xiaoxiu Li, Peiyu Chen, Kelvin Li, Jing Xie, Huan Chen, Huiwen Li, Hongli Wang, Ding-You Li, Sitang Gong
BACKGROUND: Cow's milk protein allergy (CMPA) is commonly seen in children. There have been no reports of the true prevalence of CMPA in Chinese infants. The aim of this population-based study is to determine the prevalence, clinical characteristics, and outcome of CMPA in Chinese infants. METHODS: We carried out a prospective survey in 7 participating hospitals throughout southern China. We included infants ≤12 months of age during the survey. For those suspected of CMPA, oral food challenge with cow's milk protein (CMP) was performed...
November 19, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
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