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Muscle & Nerve

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https://www.readbyqxmd.com/read/28722822/-test-retest-reliability-of-wide-pulse-high-frequency-nmes-evoked-force
#1
Daria Neyroud, Sidney Grosprêtre, Julien Gondin, Bengt Kayser, Nicolas Place
INTRODUCTION: We aimed to compare forces evoked by wide-pulse high-frequency (WPHF) neuromuscular electrical stimulation (NMES) delivered to a nerve trunk vs. muscle belly and to assess their test-retest intra- and inter-individual reliability. METHODS: Forces evoked during two sessions with WPHF NMES delivered over the tibial nerve trunk and two over the triceps surae muscle belly were compared. Ten individuals participated in four sessions involving ten 20-s WPHF NMES contractions interspaced by 40 s recovery...
July 19, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28722779/serial-diaphragm-ultrasound-studies-in-neuralgic-amyotrophy-with-bilateral-phrenic-neuropathies
#2
Rocio Garcia-Santibanez, Craig M Zaidman, Tonya Russell, Robert C Bucelli
No abstract text is available yet for this article.
July 19, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28719731/anatomical-vs-functional-motor-points-of-selected-upper-body-muscles
#3
Alexander Franz, Joschua Klaas, Moritz Schumann, Thomas Frankewitsch, Timm J Filler, Michael Behringer
Introduction We aimed to identify nerve entry points (NEP) of superficial skeletal muscles obtained by dissection of 20 human cadavers and to compare those to motor points (MP) previously obtained by electrical stimulation. Methods The biceps brachii- (BB), trapezius (TZ), latissimus dorsi (LD), pectoralis major (Pmaj) and pectoralis minor muscles (Pmin) were dissected from human cadavers. Mean values ±SD of the NEPs of each muscle were calculated. F-tests with Bonferroni corrections were used to compare NEPs and MPs...
July 18, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28719726/how-can-we-pay-the-piper-ibm-and-the-high-price-of-a-longer-life
#4
EDITORIAL
Clifton L Gooch
No abstract text is available yet for this article.
July 18, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28718962/nerve-ultrasound-showing-martin-gruber-anastomosis
#5
P Gans, N van Alfen
No abstract text is available yet for this article.
July 18, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28710794/ultrasound-assessment-of-the-sural-nerve-in-patients-with-neuropathic-pain-after-ankle-surgery
#6
Nadia Rbia, Tim H J Nijhuis, Gert R Roukema, Ruud W Selles, Cornelis H van der Vlies, Steven E R Hovius
BACKGROUND: The sural nerve may be damaged following ankle injury. The aim of our study was to determine the diagnostic utility of high-resolution sonography in patients with ankle fractures treated by open reduction and internal fixation in whom there was a clinical suspicion of sural neuropathy. METHODS: We examined the ultrasound (US) characteristics of patients with and without post-surgical sural neuropathic pain and healthy volunteers. Cross-sectional area (CSA), echogenicity and vascularization of the sural nerves were recorded...
July 15, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28692198/longitudinal-community-walking-activity-in-duchenne-muscular-dystrophy
#7
Eileen G Fowler, Loretta A Staudt, Kent R Heberer, Susan E Sienko, Cathleen E Buckon, Anita M Bagley, Michael D Sussman, Craig M McDonald
INTRODUCTION: Natural history studies for Duchenne muscular dystrophy (DMD) have not included measures of community ambulation. METHODS: Step activity (SA) monitors quantified community ambulation in 42 boys with DMD (4-16 years) with serial enrollment up to 5 years using a repeated measures mixed model. Additionally, data were compared to 10-meter walk/run (10mWR) speed to determine validity and sensitivity. RESULTS: There was a significant decline in average strides/day and all stride rates (low, moderate, high, pediatric high) as a function of age (P<0...
July 10, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28692128/carpal-tunnel-syndrome-in-inherited-neuropathies-a-retrospective-survey
#8
Francis B Panosyan, Callyn A Kirk, Devon Marking, Mary M Reilly, Steven S Scherer, Michael E Shy, David N Herrmann
INTRODUCTION: This survey was conducted to evaluate carpal tunnel syndrome (CTS) symptom severity, functional status and outcome of CTS therapies in patients with inherited neuropathies. METHODS: Validated questionnaires were used to compare symptom severity and functional status in patients with and without a diagnosis of CTS and a diagnosis of an inherited neuropathy. RESULTS: 309 patients with inherited neuropathies participated in this study...
July 10, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28686790/adipose-stem-cells-enhance-myoblast-proliferation-via-acetylcholine-and-erk1-2-signaling
#9
Roine El-Habta, Paul J Kingham, Ludvig J Backman
Introduction We investigated the interaction between adipose tissue derived stem cells (ASCs) and myoblasts in co-culture experiments. Methods Specific inductive media were used to differentiate ASCs in vitro into a Schwann cell-like phenotype (dASCs), and subsequently the expression of acetylcholine (ACh) related machinery was determined. Furthermore, the expression of muscarinic ACh receptors (mAChRs) was examined in denervated rat gastrocnemius muscles. Results In contrast to undifferentiated ASCs, dASCs expressed more choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT)...
July 7, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28681465/symptom-management-in-als-we-can-do-better
#10
EDITORIAL
Stephen A Goutman, Zachary Simmons
No abstract text is available yet for this article.
July 6, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28667708/acute-painful-autoimmune-neuropathy-a-variant-of-guillain-barr%C3%A3-syndrome
#11
Nobuhiro Yuki, Amanda C Chan, Anna Hiu Yi Wong, Takayuki Inoue, Masafumi Yokai, Takashi Kurihara, Jérôme J Devaux, Einar Wilder-Smith
Introduction We present a painful small fibre neuropathy variant of Guillain-Barré syndrome. Methods characterized by antecedent infectious symptoms, hyporeflexia and albuminocytologic dissociation. Results Two patients received intravenous immunoglobulin, and subsequently improved. IgG antibodies in their acute phase sera strongly bound to murine small nerve fibres, and the binding disappeared during the convalescent phase. Serum transfer to a murine nociceptive model induced transient alteration in thermal pain responses...
July 1, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28667691/subacute-demyelinating-peripheral-neuropathy-as-a-novel-presentation-of-late-infantile-metachromatic-leukodystrophy
#12
Hernan D Gonorazky, Kimberly Amburgey, Grace Yoon, Jiri Vajsar, Elysa Widjaja, James J Dowling
Metachromatic leukodystrophy (MLD) is a progressive white matter disease caused by mutations in the ARSA gene(1) . There are 3 clinical subtypes that vary based on age of onset and severity of presentation. The most severe subtype is the late infantile form that presents in the second year of life (after a period of normal development) with progressive motor and cognitive deterioration and occasionally seizures. Affected individuals progress to death, usually by age 5 years. MLD is typically suspected in the appropriate clinical setting by characteristic T2 changes on brain MRI...
July 1, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28667663/neuromuscular-ultrasound-findings-in-dads-variant-of-cidp
#13
Quang D Vu, Michael S Cartwright
No abstract text is available yet for this article.
July 1, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28662296/phase-iia-trial-of-fingolimod-for-als-demonstrates-acceptable-acute-safety-and-tolerability
#14
James D Berry, Sabrina Paganoni, Nazem Atassi, Eric A Macklin, Namita Goyal, Michael Rivner, Ericka Simpson, Stanley Appel, Daniela L Grasso, Nicte I Mejia, Farrah Mateen, Alan Gill, Fernando Vieira, Valerie Tassinari, Steven Perrin
INTRODUCTION: Immune activation is implicated in ALS progression. Oral fingolimod reduces circulating lymphocytes. The objective of this phase IIa randomized controlled trial was to test the short-term safety, tolerability, and target engagement of fingolimod in ALS. METHODS: Randomization was 2:1 (fingolimod:placebo). Treatment duration was four weeks. Primary outcomes were safety and tolerability. Secondary outcomes included circulating lymphocytes and whole blood gene expression...
June 29, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28662294/reliability-of-sonographic-muscle-thickness-measurements-of-the-thenar-and-hypothenar-muscles
#15
Tugce Ozekli Misirlioglu, Ozden Ozyemisci Taskiran
Introduction This study was undertaken to assess the intra-rater and inter-rater reliability of sonographic thickness measurements of the thenar and hypothenar muscles. Methods The thickness of the thenar and hypothenar muscles of both hands of 15 volunteers (7 male, 8 female) were evaluated with a 4- to 13- MHz linear probe by two examiners who were blinded to each other's measurements. Inter-rater reliability was then evaluated. To assess intra-rater reliability, the first examiner also performed a second measurement after an interval of at least one day...
June 29, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28662292/benign-and-malignant-tumors-in-the-uk-myotonic-dystrophy-patient-registry
#16
Rotana Alsaggaf, Youjin Wang, Chiara Marini-Bettolo, Libby Wood, Nikoletta Nikolenko, Hanns Lochmüller, Mark H Greene, Shahinaz M Gadalla
INTRODUCTION: In light of recent evidence that cancer is part of the myotonic dystrophy (DM) phenotype, we assessed the prevalence of benign and malignant tumors among 220 patients enrolled in the UK Myotonic Dystrophy Patient Registry, and evaluated factors associated with their development. METHODS: A survey was distributed to collect tumor history and lifestyle information. We used multinomial logistic regression for the analysis. RESULTS: Thirty-nine benign (30 patients), and 16 malignant (15 patients) tumors were reported...
June 29, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28662276/nerve-ultrasound-shows-subclinical-peripheral-nerve-involvement-in-neurofibromatosis-type-2
#17
Johan A Telleman, Menno D Stellingwerff, Geert J Brekelmans, Leo H Visser
INTRODUCTION: Neurofibromatosis type 2 (NF2) is mainly associated with central nervous system (CNS) tumors. Peripheral nerve involvement is described in symptomatic patients, but evidence of subclinical peripheral nerve involvement is scarce. METHODS: We conducted a cross-sectional pilot study in 2 asymptomatic and 3 minimally symptomatic patients with NF2 to detect subclinical peripheral nerve involvement. Patients underwent clinical examination, nerve conduction studies (NCS), and high-resolution ultrasonography (HRUS)...
June 29, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28646568/blink-r1-latency-utility-in-diagnosis-and-treatment-assessment-of-poems-and-cidp
#18
Wei Wang, William J Litchy, Michelle L Mauermann, P James B Dyck, Angela Dispenzieri, Jay Mandrekar, Peter J Dyck, Christopher J Klein
INTRODUCTION: In POEMS and CIDP, limb nerve conduction studies (NCS) are limited in identifying demyelination and detecting treatment effects in severely affected patients. Blink R1-latency may improve these assessments. METHODS: POEMS and CIDP patients having undergone NCS and blink reflex were identified. Correlations between R1-latency, limb NCS and neuropathy impairment scores (NIS) were compared. RESULTS: With182 patients (124 POEMS, 58 CIDP) identified, R1-prolongation (>13ms) occurred in 64...
June 23, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28646510/compound-muscle-action-potential-duration-in-critical-illness-neuromyopathy
#19
Christopher L Kramer, Andrea J Boon, C Michel Harper, Brent P Goodman
BACKGROUND: We sought to determine the specificity of compound muscle action potential (CMAP) durations and amplitudes in a large critical illness neuromyopathy (CINM) cohort relative to controls with other neuromuscular conditions. METHODS: Fifty-eight patients with CINM seen over a 17-year period were retrospectively studied. Electrodiagnostic findings of the CINM cohort were compared with patients with axonal peripheral neuropathy and myopathy due to other causes...
June 23, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28646486/editorial-on-ultrasonography-in-neuralgic-amyotrophy-sensitivity-spectrum-of-findings-and-clinical-correlations-by-ar%C3%A3-nyi-et-al
#20
EDITORIAL
Nens van Alfen
No abstract text is available yet for this article.
June 23, 2017: Muscle & Nerve
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