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Muscle & Nerve

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https://www.readbyqxmd.com/read/27875635/muscle-adaptations-following-21-consecutive-days-of-strength-test-familiarization-compared-with-traditional-training
#1
Scott J Dankel, Brittany R Counts, Brian E Barnett, Samuel L Buckner, Takashi Abe, Jeremy P Loenneke
INTRODUCTION: Large increases in 1-repetition maximum (1RM) strength have been demonstrated from repeated testing, but it is unknown whether these increases can be augmented by resistance training. METHODS: Five trained individuals performed a 1RM test and maximal voluntary isometric contraction (MVC) for unilateral elbow flexion exercise on 1 arm (testing arm), while the other arm performed a 1RM test and MVC, in addition to 3 sets of exercise (70% 1RM) (training arm) for 21 straight days...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27875632/variable-phenotypic-expression-and-onset-in-myh14-distal-hmn-phenotype-in-a-large-multigenerational-north-american-family
#2
Stanley Iyadurai, W David Arnold, John T Kissel, Corey Ruhno, Vicki L McGovern, Pamela J Snyder, Thomas W Prior, Jennifer Roggenbuck, Arthur H Burghes, Stephen J Kolb
INTRODUCTION: Distal hereditary motor neuropathy (dHMN) causes distal-predominant weakness without prominent sensory loss. Myosin heavy chain disorders most commonly result in distal myopathy and cardiomyopathy with or without hearing loss, but a complex phenotype with dHMN, myopathy, hoarseness, and hearing loss was reported in a Korean family with a c.2822G>T mutation in MYH14. OBJECTIVE: To report phenotypic features in a North American family with the c.2822G>T in MYH14...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27875630/eosinophilic-fasciitis-with-subjacent-myositis
#3
Julia B Whitlock, Elliot L Dimberg, Duygu Selcen, Devon I Rubin
Introduction Eosinophilic fasciitis (EF) is a rare disorder that can present with muscle symptoms that mimic other neuromuscular diseases. Methods We report a 43-year-old woman with chronic muscle aches, tightness, and stiffness with hypertrophied, well-defined muscles despite physical inactivity, and thickened skin with reduced elasticity and discoloration. Results Except for mild peripheral eosinophilia, laboratory studies, including blood count, electrolytes, paraneoplastic panel, muscle enzymes, thyroid function, and serum protein electrophoresis were normal...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27875624/a-case-of-miller-fisher-syndrome-associated-with-preceding-herpes-zoster-ophthalmicus
#4
Angelo Cascio Rizzo, Martina Ulivi, Nicoletta Brunelli, Alessio Pepe, Giovanni Assenza, Lucia Florio, Vincenzo Di Lazzaro
No abstract text is available yet for this article.
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27875622/neurographic-course-of-wallerian-degeneration-after-human-peripheral-nerve-injury
#5
Maria Eder, Wilhelm Schulte-Mattler, Peter Pöschl
INTRODUCTION: Neurographic data on Wallerian degeneration (WD) following motor nerve injury are available only from animal studies and from human case reports of 9 patients altogether. A precise knowledge of neurographic features of WD would be highly relevant for diagnostic, prognostic, therapeutic, and forensic aspects of traumatic lesions. METHODS: We prospectively studied WD in patients with a peripheral nerve injury. They underwent sequential neurographic examinations beginning no later than 3 days after the injury until a plateau of the amplitude of compound muscle action potential was reached...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27875620/a-reliable-technique-for-us-guided-perineural-injection-in-ulnar-neuropathy-at-the-elbow
#6
Ulrike M Hamscha, Ines Tinhofer, Stefan Heber, Wolfgang Grisold, Wolfgang J Weninger, Stefan Meng
INTRODUCTION: Ulnar neuropathy at the elbow (UNE) is a common peripheral compression neuropathy and in most cases occurs at 2 sites, the retroepicondylar groove or the cubital tunnel. With regard to a potential therapeutic approach with perineural corticosteroid injection the aim of this study was to evaluate the distribution of injection fluid applied at a standard site. METHODS: We performed ultrasound-guided (US-guided) perineural injections to the ulnar nerve halfway between the olecranon and the medial epicondyle in 21 upper limbs from 11 non-embalmed cadavers...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27874200/two-patients-with-gmppb-mutation-the-overlapping-phenotypes-of-limb-girdle-myasthenic-syndrome-and-lgmd2t-dystroglycanopathy
#7
Federica Montagnese, Elisabeth Klupp, Dimitrios C Karampinos, Saskia Biskup, Dieter Gläser, Jan S Kirschke, Benedikt Schoser
INTRODUCTION: Mutations in the GDP-mannose pyrophosphorylase-B gene (GMPPB) have been identified in congenital muscular dystrophies (CMDs), limb-girdle muscular dystrophy (LGMD2T), and congenital myasthenic syndromes (CMSs); overall, 41 patients have been described. METHODS: Two patients presented with a myasthenic syndrome (patient 1, 74-year-old) and rhabdomyolysis (patient 2, 23-year-old). Examinations included repetitive nerve stimulation, muscle biopsy and whole-body MRI (WBMRI); next generation sequencing facilitated diagnosis...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27874195/double-peak-sensory-nerve-action-potentials-to-single-stimuli-in-nerve-conduction-studies
#8
REVIEW
Joao Leote, Pedro Pereira, Josep Valls-Sole
Introduction In humans, sensory nerve action potentials (SNAPs) can show 2 separate deflections, i.e., double peak potentials (DPp), which necessarily means that 1 peak is delayed with respect to the other. DPps may have various origins and be due to either physical or physiological properties. Methods We review the nature of commonly encountered DPps in clinical practice, provide the most likely interpretations for their physiological origin, and assess their reproducibility and clinical utility. Results We classified the DPps into 3 categories: 1) simultaneous anodal and cathodal stimulation...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27863443/gait-assessment-with-solesound-instrumented-footwear-in-spinal-muscular-atrophy
#9
Jacqueline Montes, Damiano Zanotto, Sally Dunaway Young, Rachel Salazar, Darryl C De Vivo, Sunil Agrawal
BACKGROUND: Gait impairment is common in spinal muscular atrophy (SMA) and is described using clinical assessments and instrumented walkways. Continuous over-ground walking has not been studied. METHODS: Nine SMA participants completed the six-minute walk test (6MWT) and 10-meter walk/run wearing instrumented footwear (SoleSound). Data were simultaneously collected using a reference system (GAITRite(TM) ). The root mean square error (RMSE) indicated criterion validity...
November 18, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27859367/complete-dislocation-of-the-ulnar-nerve-at-the-elbow-a-protective-effect-against-neuropathy
#10
A Arturo Leis, Benn E Smith, Heidi E Kosiorek, Gregor Omejec, Simon Podnar
INTRODUCTION: Recurrent complete ulnar nerve dislocation has been perceived as a risk factor for development of ulnar neuropathy at the elbow (UNE). However, the role of dislocation in the pathogenesis of UNE remains uncertain. METHODS: We studied 133 patients with complete ulnar nerve dislocation to determine if this condition is a risk factor for UNE. In all, the nerve was palpated as it rolled over the medial epicondyle during elbow flexion. RESULTS: Of 56 elbows with unilateral dislocation UNE localized contralaterally in 17 (30...
November 18, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27859360/physical-function-and-mobility-in-children-with-congenital-myotonic-dystrophy
#11
Evan M Pucillo, Deanna L DiBella, Man Hung, Jerry Bounsanga, Becky Crockett, Melissa Dixon, Russell J Butterfield, Craig Campbell, Nicholas E Johnson
INTRODUCTION: Congenital Myotonic Dystrophy (CDM) occurs when symptoms of myotonic dystrophy present at birth. This study evaluated the relationship between physical function, muscle mass, and age to provide an assessment of the disease and help prepare for therapeutic trials. METHODS: CDM participants performed timed functional tests (TFTs), The first 2 minutes of the 6-minute walk test (2/6MWT), myometry, and dual-energy x-ray absorption (DEXA) scans. Healthy controls (HC) performed TFTs, 6MWT, and myometry...
November 18, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27864992/the-mri-bullseye-sign-an-indicator-of-peripheral-nerve-constriction-in-parsonage-turner-syndrome
#12
Darryl B Sneag, Eliana B Saltzman, David W Meister, Joseph H Feinberg, Steve K Lee, Scott W Wolfe
INTRODUCTION: Magnetic resonance imaging's (MRI's) role in identifying hourglass constrictions (HGCs) of nerves in Parsonage-Turner syndrome (PTS) is largely unknown. METHODS: Six patients with PTS and with absent or minimal recovery underwent MRI. Surgical exploration was performed at identified pathologic sites. RESULTS: The time between symptom onset and surgery was 12.4 ± 6.9 months; the time between MRI and surgery was 1.3 ± 0...
November 16, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27864983/diagnosis-of-unilateral-trapezius-muscle-palsy-54-cases
#13
Paul Seror, Tanya Stojkovic, Marie Martine Lefevre-Colau, Timothée Lenglet
INTRODUCTION: We assessed medical and surgical causes of unilateral trapezius muscle (TM) palsy and/or wasting. METHODS: Clinical and electrodiagnostic data were collected in 54 patients with TM impairment over 21 years. RESULTS: In total, 35 cases had a medical origin: neuralgic amyotrophy (NA, n=22), idiopathic unilateral TM palsy (n=5), regional neck radiotherapy for different conditions (n=2), facioscapulohumeral dystrophy (FSH) (n=4), abnormal loop of the jugular vein (n=1), or basilar impression (n=1)...
November 16, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862032/pleural-drop-metastases-21-years-after-resection-of-a-thymoma
#14
Chia-Chun Chiang, Angela M Parsons, J Scott Kriegshauser, Harshita R Paripati, Matthew A Zarka, A Arturo Leis
INTRODUCTION: We describe an unusual case of pleural drop metastases 21 years after complete resection of an encapsulated thymoma in a Southeast Asian with myasthenia gravis (MG). METHODS: Case report and review of literature. RESULTS: The patient presented in 2015 with generalized weakness, fatigue, and shortness of breath, but no diplopia, ptosis, dysphagia, or dysarthria. Because these symptoms were atypical for an MG exacerbation, a de novo work-up was performed...
November 16, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862026/unusual-presentation-of-sj%C3%A3-gren-associated-neuropathy-with-plasma-cell-rich-infiltrate
#15
Elie Naddaf, Sarah E Berini, P James B Dyck, Ruple S Laughlin
INTRODUCTION: Sjögren syndrome is thought to be a lymphocyte-driven process. Peripheral nervous system involvement occurs in about 20-25% of patients. A sensory predominant, large fiber peripheral neuropathy is most common, and it is usually associated with a subacute to chronic presentation. METHODS: We report a rare case of an acute Sjögren-associated, sensory predominant, length-dependent peripheral neuropathy mimicking Guillain-Barré syndrome. The patient presented with sensory ataxia preceded by fever and polyarthralgia...
November 16, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862024/medial-gastrocnemius-specific-force-of-adult-men-with-spastic-cerebral-palsy
#16
Ayser W Hussain, Gladys L Onambele, Alun G Williams, Christopher I Morse
INTRODUCTION: Muscle weakness determines functional impairment in spastic cerebral palsy (SCP). Measurement of specific force (SF) allows for strength comparison with unimpaired populations (controls) accounting for neural (activation and coactivation), architectural (fascicle length and pennation angle), and structural differences (moment arm length). METHODS: Medial gastrocnemius (MG) SF (and its determinants) was assessed in both paretic and non-paretic legs of 11 men with SCP and 11 age-matched controls during plantarflexion maximal voluntary isometric contraction (MVIC)...
November 15, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862019/bent-spine-syndrome-as-the-initial-symptom-of-late-onset-pompe-disease
#17
Nicolas Taisne, Claude Desnuelle, Raul Juntas Morales, Xavier Ferrer Monasterio, Sabrina Sacconi, Fanny Duval, Guilhem Sole, René Marc Flipo, Arnaud Lacour, Patrick Vermersch, Thierry Cardon
INTRODUCTION: Late-onset Pompe disease (LOPD) is a rare disorder characterized by progressive proximal muscle weakness and early respiratory insufficiency, for which enzyme replacement therapy (ERT) is available. METHODS: Having diagnosed a case of LOPD presenting with bent spine syndrome, we conducted a brief survey in the French centers involved in management of Pompe disease, from which we collected data on 3 other cases. RESULTS: The patients (3 women and 1 man) had a mean age of 64 years (range 51-77 years) and a delay in diagnosis of approximately 10 years (range 8-42 years)...
November 15, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27859440/peripheral-nerve-ultrasound-in-cerebellar-ataxia-neuropathy-vestibular-areflexia-syndrome-canvas
#18
Luciana Pelosi, Ruth Leadbetter, Eoin Mulroy, Andrew M Chancellor, Stuart Mossman, Richard Roxburgh
INTRODUCTION: We report preliminary findings of nerve ultrasound in patients with cerebellar ataxia neuropathy vestibular areflexia syndrome (CANVAS) who have sensory impairment due to dorsal root ganglionopathy. METHODS: The ultrasound cross-sectional area (CSA) of median and ulnar nerves of 7 CANVAS patients was compared with 7 age- and gender-matched controls and with the mean CSA of our reference population. RESULTS: The nerve CSA of CANVAS patients was significantly smaller than that of controls at all sites (P < 0...
November 15, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27859366/subcoracoid-bursitis-presenting-with-brachial-plexopathy-involving-the-posterior-cord
#19
Suk-Won Ahn, Moo-Seok Park, Il-Han Yoo, Jeong-Min Kim, Byung-Nam Yoon, Sang-Beom Kim, Jae Yoon Kim
No abstract text is available yet for this article.
November 15, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862051/comparison-of-the-ballistic-contractile-responses-generated-during-microstimulation-of-single-human-motor-axons-with-brief-irregular-and-regular-stimuli
#20
Michael Leitch, Vaughan G Macefield
INTRODUCTION: Ballistic contractions are induced by brief, high frequency (60-100 Hz) trains of action potentials in motor axons. During ramp voluntary contractions, human motoneurones exhibit significant discharge variability of ∼20% and have shown to be advantageous to the neuromuscular system. We hypothesized that ballistic contractions incorporating discharge variability generate greater isometric forces than regular trains with zero variability. METHODS: High impedance tungsten microelectrodes were inserted into the fibular nerve, and single motor axons were stimulated with both irregular and constant-frequency stimuli at mean frequencies ranging from 57...
November 11, 2016: Muscle & Nerve
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