journal
MENU ▼
Read by QxMD icon Read
search

Artificial Organs

journal
https://www.readbyqxmd.com/read/29774568/effects-of-plasma-proteins-on-the-transport-and-surface-characteristics-of-polysulfone-polyethersulfone-and-asymmetric-cellulose-triacetate-high-flux-dialyzers
#1
Tae Ryung Kim, Mahsa Hadidi, Seyed Pouria Motevalian, Takashi Sunohara, Andrew L Zydney
Blood-membrane interactions can have a large impact on the performance of hemodialysis membranes, particularly for high flux membranes in which the membrane itself provides very low resistance to solute transport. The objective of this study was to examine the effects of exposure to serum on the solute clearance and convective sieving characteristics of high flux polysulfone (Optiflux F250NR), polyethersulfone (ELISIO-25H), and asymmetric cellulose triacetate (SOLACEA-25H) hemodialyzers using both vitamin B12 and a range of polydisperse dextrans...
May 17, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29774558/clinical-outcome-and-comparison-of-three-different-left-ventricular-assist-devices-in-a-high-risk-cohort
#2
Konstantin Zhigalov, Ahmed Mashhour, Marcin Szczechowicz, Sabreen Mkalaluh, Sergei Karagezian, Irakli Gogia, Maxim Isaev, Bakitbek K Kadyraliev, Jerry Easo, Juergen Ennker, Harald C Eichstaedt, Alexander Weymann
We present a comparison between three left ventricular assist devices (LVADs): HeartWare (HVAD) (HeartWare International Inc., Framingham, MA, USA), HeartMate II (HMII) and HeartMate III (HMIII) (Thoratec Corp., Pleasanton, CA, USA). To our knowledge, no study to date has aimed at placing these three devices in juxtaposition. Between June 2007 and June 2017, 108 consecutive patients received HMII, n = 77 (71.3%), HVAD, n = 14 (13%), or HM III, n = 17 (15.7%), for end-stage heart failure. Mean age was 63...
May 17, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29774551/in-vitro-hemodynamic-evaluation-of-an-adult-pulsatile-extracorporeal-membrane-oxygenation-system
#3
Shigang Wang, Morgan Moroi, Christoph E Brehm, Allen R Kunselman, Akif Ündar
The objective of this study was to evaluate a pulsatile extracorporeal membrane oxygenation (ECMO) system in terms of hemodynamic energy generation and transmission under various pulsatile amplitudes, flow rates, and pseudopatient pressures in a simulated adult ECMO circuit. Surplus hemodynamic energy (SHE), a measure of the quality of pulsatility, was used to quantify pulsatile flow. The circuit consisted of an i-cor diagonal pump, an adult XLung oxygenator, a 21 Fr Medtronic Biomedicus femoral arterial cannula, a 23/25 Fr Sorin RAP femoral venous cannula, and 3/8 in ID tubing for both arterial and venous lines...
May 17, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29774549/extracorporeal-membrane-oxygenation-characteristics-and-outcomes-in-adult-patients-with-down-syndrome
#4
Vicky Duffy, Daniel Gomez, Peter Rycus, Brian Rivera, Stephanie L Santoro, Carl H Backes, Clifford L Cua
Patients with Down syndrome (DS) may have multiple medical issues that place them at risk for requiring extracorporeal membrane oxygenation. Use of extracorporeal membrane oxygenation in pediatric patients with Down syndrome has been described, but minimal data exist for extracorporeal membrane oxygenation use in adults with Down syndrome. The goal of this study was to describe the clinical characteristics and to determine if there were differences between adult extracorporeal membrane oxygenation patients with Down syndrome that were alive (aDS) versus those that died (dDS) prior to hospital discharge...
May 17, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29761832/psychophysical-evaluation-of-a-tactile-display-based-on-coin-motors
#5
H Christiaan Stronks, Daniel J Parker, Ashley Stacey, Nick Barnes
Tactile vision substitution devices present visual images as tactile representations on the skin. In this study we have tested the performance of a prototype 96-tactor vibrotactile using a subset of 64 tactors. We have determined the tactile spatial acuity and intensity discrimination in 14 naïve subjects. Spatial acuity was determined using a grating acuity task. Subjects could successfully identify the orientation of horizontal and vertical gratings with an average psychophysical threshold of 120 mm. When diagonal gratings were included in the analysis, the median performance dropped below psychophysical threshold, but was still significantly above chance at gratings of 142 mm wide...
May 15, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29726019/speed-modulation-of-the-heartware-hvad-to-assess-in-vitro-hemocompatibility-of-pulsatile-and-continuous-flow-regimes-in-a-rotary-blood-pump
#6
Jarod T Horobin, Michael J Simmonds, Deepika Nandakumar, Shaun D Gregory, Geoff Tansley, Jo P Pauls, Angela Girnghuber, Nicoletta Balletti, John F Fraser
Although rotary blood pumps (RBPs) sustain life, blood exposure to continuous supra-physiological shear stress induces adverse effects (e.g., thromboembolism); thus, pulsatile flow in RBPs represents a potential solution. The present study introduced pulsatile flow to the HeartWare HVAD using a custom-built controller and compared hemocompatibility biomarkers (i.e., platelet aggregation, concentrations for ADAMTS13, von Willebrand factor (vWf), and free-hemoglobin in plasma (pfHb), red blood cell (RBC) deformability, and RBC-nitric oxide synthase (NOS) activity) between continuous and pulsatile flow in a blood circulation loop over 5 h...
May 3, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29726017/effect-of-cerebral-flow-autoregulation-function-on-cerebral-flow-rate-under-continuous-flow-left-ventricular-assist-device-support
#7
Selim Bozkurt
Neurological complications in continuous flow left ventricular assist device (CF-LVAD) patients are the second-leading risk of death after multi-organ failure. They are associated with altered blood flow in the cardiovascular system because of CF-LVAD support. Moreover, an impaired cerebral autoregulation function may also contribute to complications such as hyperperfusion in the cerebral circulation under mechanical circulatory support. The aim of this study is to evaluate the effect of cerebral autoregulatory function on cerebral blood flow rate under CF-LVAD support...
May 3, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29726003/limitations-of-current-near-infrared-spectroscopy-configuration-in-detecting-focal-cerebral-ischemia-during-cardiac-surgery-an-observational-case-series-study
#8
Gabor Erdoes, Christian Rummel, Reto M Basciani, Rajeev Verma, Thierry Carrel, Yara Banz, Balthasar Eberle, Gerhard Schroth
Cerebral oximetry using near-infrared spectroscopy (NIRS) allows for continuous monitoring of cerebral perfusion and immediate treatment of hemodynamic perturbations. In configurations used in current clinical practice, NIRS optodes are placed on the patient`s forehead and cerebral oxygen saturation (ScO2 ) is determined in bilateral frontal cortical samples. However, focal cerebral ischemic lesions outside of the NIRS field of view may remain undetected. The objective of this observational case-series study was to investigate ScO2 measurements in patients with acute iatrogenic stroke not located in the frontal cortical region...
May 3, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29682761/in-vitro-hemodynamic-evaluation-of-ecg-synchronized-pulsatile-flow-using-i-cor-pump-as-short-term-cardiac-assist-device-for-neonatal-and-pediatric-population
#9
Madison Force, Morgan Moroi, Shigang Wang, Allen R Kunselman, Akif Ündar
The objective of this study was to assess the hemodynamic properties of the i-cor ECG-synchronized cardiac assist system for off-label use as a short-term cardiac assist device for neonatal and pediatric patients and compare nonpulsatile to pulsatile flow with different amplitudes. The circuit consisted of the i-cor diagonal pump with 3 feet of ¼ inch arterial and venous tubing and a soft-shell reservoir, primed with lactated Ringer's solution and human packed red blood cells (hematocrit 42%). Trials were conducted with three different sets of cannulas (8-Fr arterial 10-Fr venous, 10-Fr arterial 12 Fr-venous, and 12-Fr arterial 14-Fr venous) with increasing flow rates at varying pseudo-patient pressures (40, 60, 80, and 100 mm Hg) and under nonpulsatile mode and pulsatile mode with pulsatile amplitudes 2000, 2500, and 3000 rpm at 36°C...
April 22, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29682748/successful-practice-transitioning-between-hemodialysis-and-hemodiafiltration-in-outpatient-units-ten-key-issues-for-physicians-to-remember
#10
Tibor Fülöp, Mihály B Tapolyai, Lajos Zsom, Miklos Z Molnar, Sohail Abdul Salim, László Újhelyi, Gergely Becs, József Balla, Mehrdad Hamrahian
Hemodiafiltration (HDF) during chronic renal replacement therapy (RRT) is a relatively new practice phenomenon, emerging over the last two decades. While the technological platforms utilized during chronic RRT are in many cases similar or effectively identical to conventional hemodialysis (HD), significant differences may emerge in daily practice. Several authors of this review moved practice site between the United States and the European Union and transitioned from an HD-based practice to predominantly HDF-practicing networks...
April 22, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29675919/therapy-and-outcome-of-staphylococcus-aureus-infections-of-intracorporeal-ventricular-assist-devices
#11
Miquel B Ekkelenkamp, Mats T Vervoorn, Jumamurat R Bayjanov, Ad C Fluit, Barry J Benaissa-Trouw, Faiz Z Ramjankhan
Infection of the driveline or pump pocket is a common complication in patients with ventricular assist devices (VADs) and Staphylococcus aureus is the main pathogen causing such infections. Limited evidence is currently available to guide the choice of antibiotic therapy and the duration of treatment in these patients. Patients at the University Medical Center Utrecht who developed a VAD-related S. aureus infection between 2007 and 2016 were retrospectively assessed. Blood culture isolates were typed by whole genome sequencing to differentiate between relapses and reinfections, and to determine whether antibiotic therapy had led to acquisition of resistance mutations...
April 19, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29667205/application-of-heparin-collagen-redv-selective-active-interface-on-eptfe-films-to-enhance-endothelialization-and-anticoagulation
#12
Yaping Shan, Bing Jia, Ming Ye, Hua Shen, Weicheng Chen, Huifeng Zhang
Expanded polytetrafluoroethylene (ePTFE) prosthetic valves have been widely used in clinical applications in Asian countries. However, these valves still have limits with regard to thrombosis, neointimal hyperplasia, restenosis, and valvar vegetation. The achievement of in situ endothelialization on implant materials is a promising way to overcome those limits. Here, heparin/collagen multilayers were fabricated on ePTFE films via a layer-by-layer (LBL) self-assembly technique, and then, the endothelial cell (EC) adhesive peptide sequence Arg-Glu-Asp-Val (REDV) was immobilized on the multilayers...
April 18, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29663430/effectiveness-of-a-new-single-needle-single-pump-dialysis-system-with-simultaneous-monitoring-of-dialysis-dose
#13
Wolfgang Bieser, Markus Welsch, Marten Jakob, Jörn Meibaum, David A Rodriguez, Henrik Wolff, Daniele Marcelli, Claudia Barth
To date, single-needle (SN) hemodialysis (HD) requires a dialysis machine equipped with two blood pumps-one controlling arterial blood flow (Qb) and one controlling venous Qb. B. Braun has developed an innovative single-pump SN HD system. Therefore, usability is improved by reducing complexity. The aim of this study was to compare dialysis parameters of the new single-pump SN HD system with a double-pump SN HD system available on the market (Fresenius Medical Care [FMC] 5008). In this two-armed crossover study, patients were randomized into two groups (B...
April 16, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29660857/impact-of-different-perfusion-modalities-on-coronary-and-carotid-blood-flow-velocities-in-an-adult-ecls-swine-model
#14
Shigang Wang, Sunil Patel, Jenelle M Izer, Joseph B Clark, Allen R Kunselman, Ronald P Wilson, Akif Ündar
The objective of this study was to compare the effects of nonpulsatile and ECG-synchronized pulsatile extracorporeal life support on coronary and carotid blood flow velocities using transthoracic echocardiography and vascular ultrasound, respectively. Nine adult swine were randomly separated into nonpulsatile (NP, n = 5) and pulsatile (P, N = 4) groups and placed on ECLS for 24 h using an i-cor ECLS system. Noninvasive transthoracic images of the left and right coronary artery and the left carotid artery were acquired at the pre-ECLS (baseline), 30 min, 3, 6, 9, 12, and 24 h on-ECLS stages...
April 16, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29660797/repair-of-a-giant-omphalocele-in-an-infant-with-a-pericardial-implant-crosslinked-with-oligourethane
#15
Juan Vargas-Mancilla, María A Torrero-Serrato, Aarón J Palacios-Rodríguez, Gloria B Rodríguez-de León, Metzeri I Montes-Rodríguez, Birzabith Mendoza-Novelo
The giant omphalocele (GO) represents a challenge for the pediatric surgeon in its management and wall abdominoplasty. Here, we report the outcome of a case in which a GO in a newborn patient was repaired with an implant derived from decellularized bovine pericardium crosslinked with oligourethane. The implantation time was extended for 6 months. This was then followed up by the retrieval of the implant and the subsequent reconstruction in a second surgical time by the closure of the abdominal wall fascia...
April 16, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29660790/development-of-a-tissue-engineered-artificial-ligament-reconstruction-of-injured-rabbit-medial-collateral-ligament-with-elastin-collagen-and-ligament-cell-composite-artificial-ligament
#16
Masaki Hirukawa, Shingo Katayama, Tatsuya Sato, Kota Inoue, Kosuke Niwa, Naoya Ito, Tetsuya Hattori, Takashi Hosoi, Hironori Unno, Yoshiaki Suzuki, Masahiro Hasegawa, Keiichi Miyamoto, Takashi Horiuchi
Ligament reconstruction using a tissue-engineered artificial ligament (TEAL) requires regeneration of the ligament-bone junction such that fixation devices such as screws and end buttons do not have to be used. The objective of this study was to develop a TEAL consisting of elastin-coated polydioxanone (PDS) sutures covered with elastin and collagen fibers preseeded with ligament cells. In a pilot study, a ring-type PDS suture with a 2.5 mm (width) bone insertion was constructed with/without elastin coating (Ela-coat and Non-coat) and implanted into two bone tunnels, diameter 2...
April 16, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29633282/visual-evoked-potential-recovery-by-subretinal-implantation-of-photoelectric-dye-coupled-thin-film-retinal-prosthesis-in-monkey-eyes-with-macular-degeneration
#17
Toshihiko Matsuo, Tetsuya Uchida, Jun Sakurai, Koichiro Yamashita, Chie Matsuo, Tomoaki Araki, Yusuke Yamashita, Kunihisa Kamikawa
Retinal prosthesis or artificial retina is a promising modality of treatment for outer retinal degeneration, caused by primary and secondary loss of photoreceptor cells, in hereditary retinal dystrophy and age-related macular degeneration, respectively. Okayama University-type retinal prosthesis (OUReP) is a photoelectric dye-coupled polyethylene film which generates electric potential in response to light and stimulates nearby neurons. The dye-coupled films were implanted by vitreous surgery in the subretinal space of monkey eyes with macular degeneration which had been induced by cobalt chloride injection from the scleral side...
April 6, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29611214/hydrogen-gas-does-not-ameliorate-renal-ischemia-reperfusion-injury-in-a-preclinical-model
#18
Sarah A Hosgood, Tom Moore, Maria Qurashi, Tom Adams, Michael L Nicholson
In renal transplantation, ischemia reperfusion injury impairs early graft function and can reduce long term graft survival. Hydrogen has antioxidant and anti-inflammatory properties that can reduce the effects of ischemic injury. The aim of this study was to examine the effects of hydrogen gas administered during reperfusion in a preclinical model of kidney ischemia reperfusion injury. Porcine kidneys underwent 15 min of warm ischemia followed by 22 h of cold ischemia. They were then reperfused for 6 h with whole autologous blood on an ex vivo reperfusion circuit...
April 2, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29611212/design-of-bioartificial-pancreases-from-the-standpoint-of-oxygen-supply
#19
Hiroo Iwata, Yusuke Arima, Yusuke Tsutsui
A bioartificial pancreas (BAP), in which islets of Langerhans (islets) are enclosed in a semipermeable membrane, has been developed to realize islet transplantation without the use of immunosuppressive drugs. Although recent progress in induced pluripotent stem (iPS) and embryonic stem (ES) cells has attracted attention owing to the potential applications of these cells as insulin-releasing cells, concerns about the safety of implantation of these cells remain. The use of the BAP has the advantage of easy removal if insulin-releasing cells derived from iPS/ES cells undesirably proliferate and form tumors in the BAP...
April 2, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29611208/the-effect-of-on-line-hemodiafiltration-vegetarian-diet-and-urine-volume-on-advanced-glycosylation-end-products-measured-by-changes-in-skin-auto-fluorescence
#20
Arkom Nongnuch, Andrew Davenport
Increasing urea clearance by hemodialysis (HD) has not improved patient survival. Hemodiafiltration (HDF) has been reported to reduce cardiovascular mortality. HDF increases middle sized solute clearances. Advanced glycosylation end products (AGEs) are associated with increased cardiovascular mortality. We wished to determine whether HDF reduces AGEs. Skin auto-fluorescence (SAF) measures circulating AGEs deposited in the skin. We compared SAF measurements 12 months apart in high flux HD and HDF patients. At enrollment SAF was not different (HD 3...
April 2, 2018: Artificial Organs
journal
journal
27299
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"