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Clinical and Experimental Obstetrics & Gynecology

C r Gaggero, S Bogliolo, P Sala, C Molinari, M Motzo, E Fulcheri, P Anserini, P De Biasio
PURPOSE OF INVESTIGATION: Hydatidiform mole (HM) is an abnormal pregnancy characterized by proliferation of cytotrophoblast and syncytiotrophoblast and vesicular swelling of placental villi. The fetus or embryo can be absent or abnormal. HMs can be complete or partial. CASE REPORT: A case of diginyc partial HM at 12 weeks of gestational age was referred to the present center of prenatal diagnosis. The patient showed ovarian hyperstimulation syndrome. At ultrasonography, increased fetal nuchal translucency (NT) with fetal anomaly was evident, without sonographic signs of placental mole...
2016: Clinical and Experimental Obstetrics & Gynecology
R Bedir, I Sehitoglu, G Balik, M Kagitci, H Gucer, C Yurdakul, P Bagci
OBJECTIVE: Nectins are immunoglobulin-like adhesion molecules, and they play important role in cell proliferation and tumor metastasis. The objective in this study was to compare the expression of Nectin-4 in normal endometrium and in ectopic endometriotic tissues. MATERIALS AND METHODS: Nectin-4 expression was investigated in ovarian endometriosis (n = 20), peritoneal endometriosis (n = 20), endometrium of endometriosis (n = 20), and in a control group (having no endometriosis) (n = 20) by immunohistochemical method...
2016: Clinical and Experimental Obstetrics & Gynecology
M A Guven, O Koc, H Bodur, S Erkanli, T Bagis, D Usal
Twin reversed arterial perfusion (TRAP) sequence is a serious condition of monochorionic twin pregnancy, occurring in approximately one in 35,000 cases. First trimester treatment of TRAP sequence is controversial with higher incidence of procedure related complications. Present case demonstrates a TRAP sequence that was managed by intrauterine treatment with one-ml 100% pure alcohol injection into the abdominal part of the umbilical artery and obliteration of the acardiac twin at 14 weeks of gestation. Antenatal follow-up was uneventful and elective cesarean section was performed at 39 weeks' gestation...
2016: Clinical and Experimental Obstetrics & Gynecology
N Obeidat, B Sallout, W ALAAli
Sub-diaphragmatic extralobar pulmonary sequestration (PS) is an extremely rare malformation defined as a portion of lung tissue that is totally discontinuous from the tracheobronchial tree and usually has its own pleural covering with an anomalous systemic blood supply. It is usually associated with other congenital malformations. The authors present an extremely rare case of isolated sub-diaphragmatic PS which was antenatally detected and followed up with postnatal ultrasound, where it masqueraded as a suprarenal mass; it was totally asymptomatic with spontaneous resolution at age of two years...
2016: Clinical and Experimental Obstetrics & Gynecology
R Słopień, M Pawlak, A Warenik-Szymankiewicz, S Sajdak
The study describes the case of a patient, in which as a result of removing an endometrioid ovarian cyst, there was an improvement as regards hirsutism and the decrease of testosterone concentration in the serum of peripheral blood.
2016: Clinical and Experimental Obstetrics & Gynecology
R Narayan, M Peres, G Kesby
Bartter syndrome is a rare heterogeneous group of autosomal-recessive salt-losing renal tubular disorders that can present in fetal life (antenatal Bartter syndrome; ABS) as "unexplained" early-onset polyhydramnios, often associated with growth restriction. Prenatal diagnosis of the condition involves assessment of amniotic fluid biochemistry in a setting of polyuric polyhydramnios; with elevated chloride levels considered a consistent and diagnostic finding. Other amniotic fluid biochemical markers have been described, notably increased aldosterone levels, and low total protein levels...
2016: Clinical and Experimental Obstetrics & Gynecology
X H Yang, Y Q Xu, X L Chen, S Zhao, L Zhang, D Pugash
This article reports a case of prenatal ultrasonographic diagnosis and monitoring of the twin reversed arterial perfusion (TRAP) sequence pump twin and describes progression of the disorder to a severe heart failure and fetal death. Genetic analyses were also performed for both fetuses by array-based comparative genomic hybridization (aCGH).
2016: Clinical and Experimental Obstetrics & Gynecology
P Bakas, C Tzouma, M Creatsa, I Boutas, D Hassiakos
PURPOSE OF INVESTIGATION: To report a rare case of maternal hyperthyroidism after intrauterine insemination due to hypertrophic action of hCG. MATERIALS AND METHODS: A 36-year-old woman after successful intrauterine insemination and triplet pregnancy, developed hyperthyroidism with resistance to medical treatment. RESULTS: All signs of hyperthyroidism resolved and the results of thyroid function tests returned to normal without any medication after embryo meiosis...
2016: Clinical and Experimental Obstetrics & Gynecology
I Brunel, S Iacoponi, A Hernandez, M D Diestro, J De Santiago, I Zapardiel
Intravenous leiomyomatosis (IVL) is a rare benign condition characterized by the proliferation of smooth muscle cells originating from either the uterine venous wall or a uterine myoma. This leiomyomatosis extends most frequently to pelvic vessels, but also occasionally into the inferior vena cava and right cardiac chambers. Preoperative diagnosis is difficult and it should be suspected in the presence of cardiac or pelvic masses in women who have undergone hysterectomy or myomectomy previously. The treatment is hysterectomy, normally associated with a bilateral oophorectomy and removing the mass or metastasis if any...
2016: Clinical and Experimental Obstetrics & Gynecology
Z Kamalak, N Köşüş, Ü Isaoğlu, E Ç Tanriverdi, N Isaoğlu
Data consistently show that in experienced trained hands, laparoscopic tubal sterilization is safe and highly effective regardless of the approach or occlusive method. The known mortality rate is between four and eight deaths per 100,000 cases and the rate of intraoperative and postoperative major complications is less than 1%. The anesthetic complication rate for laparoscopy is between 0.016% and 0.75%. Carbon dioxide (CO2) pneumoperitoneum effects are still controversial. Here the authors present a case report of patient who suffered from intraoperative cardiac arrest during laparoscopic tubal ligation under general anesthesia...
2016: Clinical and Experimental Obstetrics & Gynecology
G P Fragulidis, F V Oreopulu, A Vezakis, C Sofoudis, E Kalambokas, V Koutoulidis, N F Vlahos
Endometriosis represents a main cause of infertility and pelvic pain affecting 3-43% among reproductive age women. Deep pelvic endometriosis is defined as subperitoneal infiltration of endometrial implants in the uterosacral ligaments, rectum, rectovaginal septum, vagina or bladder. The authors present a case of a 29-year-old patient who underwent laparoscopic excision of extensive endometriotic plaque in rectovaginal septum accompanied with deeply infiltrating endometriosis (DIE) and chronic pelvic pain (CPP)...
2016: Clinical and Experimental Obstetrics & Gynecology
A Nishikawa, S Matsuzaki, K Mimura, T Kanagawa, T Kimura
PURPOSE: The influence of the B-Lynch suture technique on subsequent fertility and pregnancy outcomes is not clear. In the present report, the authors describe the case of a very short interpregnancy interval following the successful placement of a B-lynch suture and discuss the associated problems. MATERIALS AND METHODS: A 33-year-old-woman underwent cesarean section after undergoing artificial induction of labor and subsequent atonic postpartum hemorrhage. Placement of a B-Lynch brace suture successfully stopped the bleeding and preserved the uterus...
2016: Clinical and Experimental Obstetrics & Gynecology
M Miccini, M Gregori, D Ferraro, A Ciardi, S Cassibba, D Biacchi
Abdominal scar endometriosis, corresponding to the presence of an endometrial tissue near or inside an abdominal surgical incision, is a rare clinical event that can occur in women after gynecological or obstetric surgery. Generally, a triad consisting of underlying mass at the incision, cyclic menstrual scar pain, and history of previous gynecological or obstetric surgery leads to the preoperative diagnosis. In rare cases, the clinical presentation is atypical and the differential diagnosis with incarcerated incisional hernia, granuloma, abscess or other soft tissue tumors can be difficult...
2016: Clinical and Experimental Obstetrics & Gynecology
Z Kamalak, N Köşüş, A Köşüş, D Hizli, B Akçal, H Kafali, M Canbal, Ü Isaoğlu
OBJECTIVE: The impact of being an adolescent and socio-demographic parameters on depression development during pregnancy were evaluated in this study. MATERIALS AND METHODS: Between September 2010 and September 2011, 105 consecutive adolescent women ≤ 17 years of age were defined as the study group and 105 consecutive pregnant women over 18 years of age and matched for gestational age, were defined as the control group. Groups were compared according to depression development...
2016: Clinical and Experimental Obstetrics & Gynecology
Shao-Hui Chen, Zhao-Ai Li, Xiu-Ping Du
OBJECTIVE: To evaluate the safety and efficacy of robot-assisted laparoscopy (RAL) versus conventional laparoscopy (CL) in the treatment of advanced stage endometriosis. MATERIALS AND METHODS: Utilizing electronic databases (PubMed, Embase, and Elsevier), a systematic literature review was performed between 2008 and 2015 to compare the RAL surgery with CL surgery (CLS) in the treatment of advanced stage endometriosis. According to meta-analysis criteria, two comparative clinical trials were selected...
2016: Clinical and Experimental Obstetrics & Gynecology
D X Zhou, X Y Bian, X Y Cheng, P Xu, Y F Zhang, J X Zhong, H Y Qian, S Huang
OBJECTIVE: The aim of this study was to investigate the impacts of late gestational liver dysfunction and its impact on pregnancy outcomes. MATERIALS AND METHODS: The patients hospitalized for liver dysfunction in their late pregnancy between 2010-2012 were set as the observation group, and the pregnant women with normal liver function at the same period were randomly selected and set as the control group. The impacts towards the pregnancy outcomes were compared between these two groups and the impacts of different-degree transaminase increasing towards the pregnancy outcome were analyzed...
2016: Clinical and Experimental Obstetrics & Gynecology
H C Özcan, E Öztürk, S Sucu, M G Uğur, I Kutlar, O Balat, B Erbağci
PURPOSE OF INVESTIGATION: This study aims to investigate whether hydatidiform mole (HM) disease with malignant potential is significantly associated with increased sialic acid (SA) levels. MATERIALS AND METHODS: A total of 114 women were enrolled in this study. Patients were divided into three groups including HM (Group 1, n = 34), control group including non-pregnant healthy patients (Group 2, n = 42), and another control group including healthy pregnant patients within 12 weeks of gestation (Group 3, n = 38)...
2016: Clinical and Experimental Obstetrics & Gynecology
L Shuang, W Jidong, P Hongjuan, Y Zhenwei
OBJECTIVE: To investigate the influence of apelin on proliferation and apoptosis in rat ovarian granulosa cells (GCs) in vitro. MATERIALS AND METHODS: Primary culture of SD rat ovarian GCs was cultured with different concentrations of apelin 10(-8) mol/L, and APJ expression in GCs was inhibited by small RNA interfering (siRNA). Signaling inhibitor LY294002 of PI3K/Akt, HIMO intervention, MTT assay and flow cytometry were combined to observe the cell proliferation and apoptosis; Western blot was used to detect signaling protein expression related with cell apoptosis...
2016: Clinical and Experimental Obstetrics & Gynecology
P Anninos, P Anastasiadis, A Adamopoulos, A Kotini
This article reports the application of non-linear analysis to biomagnetic signals recorded from fetal growth restriction, fetal brain activity, ovarian lesions, breast lesions, umbilical arteries, uterine myomas, and uterine arteries in a Greek population. The results were correlated with clinical findings. The biomagnetic measurements and the application of non-linear analysis are promising procedures in Obstetrics and Gynecology.
2016: Clinical and Experimental Obstetrics & Gynecology
K Özerkan, B C Demir, S Baykara, K Aslan
OBJECTIVE: To determine the importance of placental membrane microscopic chorionic pseudocysts (MCP) in preeclamptic and normal placentas and evaluate the association between MCP and neonatal complications in preeclamptic patients. MATERIALS AND METHODS: In this prospective case-control study, microscopic examination of placentas was performed, including MCP count, in 33 preeclamptic and 35 normal control pregnant women from December 2008 to May 2009. The MCP were counted in placentas for each patient and modeled as a continuous variable to assess the difference between the two groups...
2016: Clinical and Experimental Obstetrics & Gynecology
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