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African Journal of Medicine and Medical Sciences

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https://www.readbyqxmd.com/read/29462536/type-1-diabetes-mellitus-and-graves-disease-in-down-s-syndrome-a-rare-combination
#1
T O Akande, J O Adeleye, N Sepu, O I Awofisoye
BACKGROUND: Autoimmune diseases including thyroid. disorders, type 1 diabetes and celiac disease are commoner in persons with Down's syndrome compared with the general population. Coexistent type 1 diabetes and hyperthyroidism in Down's syndrome is however not commonly reported in literature. OBJECTIVE: To report a case of a lady presenting with Graves' disease and type 1 diabetes at the same time. CLINICAL PRESENTATION: We report the case of a 22- year-old lady with Down's syndrome who presented with weight loss, polyuria and polydipsia...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462535/zinc-salt-enhances-gastroprotective-activity-of-risperidone-in-indomethacin-induced-gastric-ulcer
#2
F S Oluwole, C Onwuchekwa
BACKGROUND: Zinc has been reported to mediate cellular responses to injury by producing cytoprotection via the scavenging of reactive oxygen species. Anti-stress medications are generally anti-psychotic drugs and anti- depressants. Some Anti-psychotic drugs such as risperidone have been reported to possess anti-ulcer activity. Risperidone as an antipsychotic drug blocks several neurotransmitter systems including dopaminergic, adrenergic, histaminergic and serotonergic pathways. METHOD: The study investigated the antiulcer activity of Zinc Chloride (ZnCl(2)) in combination with risperidone in male Wistar rats...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462534/knowledge-and-attitude-of-sexually-transmitted-diseases-among-adolescents-in-ikeji-arakeji-osun-state-in-south-western-nigeria
#3
M E Akokuwebe, B Daini, E O Falayi, O Oyebade
BACKGROUND: Globally, sexually transmitted disease (STD) is a public health problem. In Nigeria, adolescents form a substantial proportion (22%) of the population and are particularly prone to STDs because of the influence of peer pressure and urge to experiment sexual activity. The study examined the knowledge and attitude of adolescents towards the prevention of sexually transmitted diseases. METHOD: The survey study was descriptive cross- sectional and carried out among consenting secondary school students aged 10-24 years completing a self- administered questionnaire on knowledge and attitude in relation to sexually transmitted diseases in Ikeji- Arakeji, Oriade Local government, Osun State, Nigeria...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462533/awareness-and-distribution-of-abo-rhesus-blood-groups-and-haemoglobin-phenotypes-among-medical-undergraduates-in-a-nigerian-university
#4
T S Akingbola, S Yuguda, O O Akinyemi, S Olomu
BACKGROUND: In the past two decades the Nigerian government and religious organisations have put more emphasis on knowing the haemoglobin electrophoresis of school children and intending couples respectively. Knowledge of the distribution of blood groups and haemoglobin electrophoretic patterns among young people is vital for the prevention of haemoglobinopathies in the population and for providing effective blood banking services. Therefore, this study was designed to assess the frequency and awareness of blood group and haemoglobinphenotypes among a new set of fourth year clinical medical and dental students of the University of Ibadan, Nigeria...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462532/functional-health-of-patients-with-knee-osteoarthritis-in-a-family-medicine-clinic-in-ibadan
#5
T Ilori, M M Ladipo, A M Ogunbode
BACKGROUND: Patients with knee osteoarthritis experience pain and functional impairment, which impacts upon activities of daily living ultimately leading to a loss of functional independence and low quality- of-life. This study therefore aimed at evaluating the functional health status of patients with knee osteoarthritis in the Family Medicine clinic, University College Hospital, Ibadan, Nigeria. METHODS: A cross-sectional study was conducted on 270 eligible respondents between January and March 2011...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462531/constraints-in-the-neurosurgical-management-of-pituitary-tumours-in-an-african-developing-country-a-5-year-observational-study-from-benin-republic
#6
H J Gandaho, A O Adeleye, A Kerekou, P Yekpe, F Djrolo
INTRODUCTION: Benin Republic, a very low-income-sub- Saharan African developing country, has a severely resource-constrained health system. There is hardly any data available on the pattern of pituitary tumour in this country METHODS: A single surgeon, hospital-based retrospective analysis of the pattern, presentation and clinical / surgical course of7a prospective cohort of pituitary tumours seen over a 5-year period is presented RESULTS: There were 38 cases, 20 (52.6%) female; 27% of all brain tumours seen...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462530/neuroprotective-effects-of-kolaviron-against-psycho-emotional-stress-induced-oxidative-brain-injury-in-rats-the-whisker-removal-model
#7
G F Ibironke, A A Fasanmade
BACKGROUND: The study investigated the neuroprotective potentials of kolaviron (a biflavonoid complex of Garcinia kola) against psycho-emotional stress induced oxidative brain injury in Wistar rats. METHODS: Twenty-four adult Wistar rats (180-220g) randomly divided into four groups (1-1V,n=6) were used for the study . Group 1 served as control (non stressed), group 11 consisted of stressed rats induced by complete removal' of the whiskers around the mouth and the nose without anaesthesia...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462529/accuracy-of-non-endoscopic-predictors-of-oesophageal-varices-in-liver-cirrhosis-using-platelet-count-splenic-size-and-portal-vein-diameter
#8
K O Akande, A Akere, J A Otegbayo, S O Ola, D Ousunmade
BACKGROUND: Endoscopy has been recommended for all patients with liver cirrhosis to detect varices, but it is expensive, invasive and uncomfortable. There is therefore, need to find non-endoscopic means to predict oesophageal varices. AIM: To determine the sensitivity and specificity of platelet count, splenic size and portal vein diameter to predict oesophageal varices in patients with liver cirrhosis. METHODOLOGY: Subjects were patients with liver cirrhosis and controls without liver disease aged 18 years and above...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462528/changes-in-kidney-function-and-oxidative-stress-biomarkers-in-offspring-from-dams-treated-with-dexamethasone-during-lactation-in-wistar-rats
#9
S O Jeje, O O Akindele, G Ushie, Y Rajil
BACKGROUND: The effects of maternal exposure to glucocorticoids during gestation on various organs in the offspring have been reported in literature. There is paucity of information on the effects of maternal glucocorticoids treatment during lactation on organ functions in the offspring. The present study was designed to investigate the changes in kidney function and oxidative stress biomarkers in offspring of dams treated with dexamethasone during lactation in Wistar rats METHODS: Twenty pregnant rats (180-200g) were divided into 4 groups (n=5)...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462527/dealing-with-diabetes-specific-emotional-distress-a-cross-sectional-survey-of-physical-activity-option
#10
A F Adeniyi, O O Ogwumikel, I A Adegboyega, J O Adeleye
BACKGROUND: Diabetes-specific emotional distress is common among people with type 2 diabetes due to the complexities associated with care and maintenance of wellness among the patients. Unlike the focus on glycaemic control, literature appears unavailable about how physical activity may help in the control of diabetes-specific emotional distress. This study was conducted to investigate the link between diabetes- specific emotional distress and physical activity. METHODOLOGY: Type 2 diabetes patients (n = 206) were enrolled into this study from two major health care facilities in Ibadan, Southwestern Nigeria...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29462526/essential-professional-duties-for-the-sub-saharan-medical-dental-graduate-an-association-of-medical-schools-of-africa-initiative
#11
E O Olapade-Olaopa, N Sewankambo, J E Iputo, P Rugarabamu, A H Amlak, M Mipando, Monekosso G L
BACKGROUND - Globally, human resources for health are being optimized to address the increasing health burden and concomitant increased demands on health professionals. These demands are even more exacting in Sub-SaharanAfrica considering the shortage of health care workers, especially physicians. The noteworthy efforts at deploying task-shifting to address this situation not-withstanding, the situation also signals the need to re-define the objectives of medical instruction to ensure effective and contemporary medical practice in a mostly physician-led health workforce across the sub-continent...
September 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465864/endodontic-flare-up-incidence-and-association-of-possible-risk-factors
#12
S O Gbadebo, A O Sulaiman, O O Anifowose
BACKGROUND: Endodontic emergency during root canal treatment (flare up) is a common occurrence in multivisit root canal treatment (RCT) and it may be associated with many factors. The occurrence however can affect the prognosis of the tooth and the patient -clinician relationship. AIM: To determine the incidence and risk factors associated with occurrence of flare up in a multi visit RCT. METHODOLOGY: Patients planned for multi-visit (RCT) were recruited for the research...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465863/methods-of-voluntary-reporting-medication-administration-errors-among-nurses-in-the-university-college-hospital-ibadan-nigeria
#13
R E Ilesanmi, E O Okojie, A C Ojerinde
BACKGROUND: Reporting medication administration error (MAEs) is a significant strategy to ensure patient safety. Literature had it that most of what is reported as errors of administration is just a tip of the iceberg, suggesting that a lot more go unreported. The methods of reporting medication administration errors in Nigeria have not been well explored. This study examined the methods of reporting MAEs by nurses in selected wards. in the University College Hospital, Ibadan. Nigeria...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465862/validation-of-a-yoruba-version-of-the-arthritis-self-efficacy-scale
#14
B O A Adegoke, A C Odole, A T Adekunle-Balogun, I Umar
BACKGROUND: The Arthritis Self Efficacy Scale (ASES) measures a patient's perceived efficacy to cope with the consequences of chronic arthritis. The aim of this, study was to translate ASES in to Yoruba, one of the indigenous Nigerian languages, and to investigate the validity and reliability of the translated version. METHODS: Forty one (21 males; 20 females).patients diagnosed with arthritis participated in this cross sectional survey, although only thirty seven (87...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465861/a-prospective-study-of-adverse-events-to-antiretroviral-therapy-in-hiv-infected-adults-in-ekiti-state-nigeria
#15
T D Popoola, O Awodele, K A Oshikoya
OBJECTIVES: Highly active antiretroviral therapy (HAART); the-current standard of antiretroviral therapy for Human Immunodeficiency Virus (HIV) infected persons, has been documented to drastically, reduce the number of cases of Acquired Immune Deficiency Sypdrome (AIDS). However, adverse. events are a challenge to the use of HAART. This study intends to determine the nature and incidence of suspected advcrse events to prescribed anti retroviral drugs in treatment centers in Ekiti State...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465860/sport-participation-and-injuries-among-undergraduate-students-of-a-nigerian-university
#16
O B A Owoeye, S R A Akinbo, S O Giwa
Backgroud: Sports participation is a healthy behaviour but it is not without the risk of injuries. Information on the extent of sport participation and sport injuries among Nigerian Unversity students is sparse. Objeclive: To determine the prevalence and types of sport participation and injuries among university.students in Nigeria. Factors associated with sport participation among students were also examined. METHODS: A cross-sectional survey was conducted using a self-administered questionnaire to collect information on the frequcncy and types of sport participation and sport-related injuries among a representative sample of undergraduate students of the University of Lagos, Nigeria...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465859/spectrophotometric-studies-of-a-novel-gedunin-2-hydroxypropyl-%C3%AE-cyclodextrin-binary-system
#17
M O Ologe, A O Adegoke, E O Iwalewa, O G AdeMowo
BACKGROUND: Gedunin, a limonoid, is linked with antimalarial, anticancer and anti-allergic activities. This study was aimed at preparing an inclusion complex of gedunin and 2-hydroxypropyl-p-cyclodextrin (HBD) to increase solubility of-gedunin in polar solvents which will increase absorption and bioavailability in vivo and thus enhance pharmacological effects. MATERIALS AND METHODS: Gedunin was obtained from the hexane extract of Entandrophragma angolense heartwood by column and preparative thin layer chromatography...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465858/perception-attitude-and-willingness-of-under-five-children-caregivers-to-growth-monitoring-in-ibadan-south-west-local-government-area-oyo-state-nigeria
#18
O Abiona, O Oladepo
OBJECTIVE: This study was carried out to explore perceptions ofunder five caregivers on growth monitoring in Ibadan south-west local government in Nigeria. METHOD: Descriptive. cross-sectional-design was used for the study which involved four-stage sampling techniques. The study was conducted among the 410 caregivers who consented to participate. Both qualitative and quantitative methods were used to collect the data. The questionnaire elicited information on sociodemographic characteristics, Knowledge, Attitude and Growth -Monitoring perceptions were measured on a 16-point scale and categorizedinto "negative" (≤8) and positive (>8) Descriptive statistics -using mean and standard deviation were generated while qualitative data was analysed using Atlas Ti version 7...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465857/dental-care-seeking-behaviour-of-children-in-a-rural-nigerian-community
#19
F B Lawal, O Ibiyemi, J O Taiwo, G A Oke
BACKGROUND: There is sparse information about oral health seeking behaviour of children in rural areas of developing countries. The aim of the Study was to determine the dental care seeking-behaviour of children attending the first rural based community oral health centre in Nigeria. METHODS: A retrospective review of records of patients aged 16 years or younger treated at the Primary Oral Health Care Centre in Ibarapa, Nigeria over six years was conducted. Data on sociodemographic characteristics of the patients, pattern of presentation and their oral hygiene practices were collected and processed using SPSS...
June 2016: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/29465856/bacteriology-of-middle-meatal-aspirate-of-adult-patients-with-chronic-rhinosinusitis-in-lagos-university-teaching-hospital-lagos
#20
S M Oladeji, C C Nwawolo, A J Fasunla, C J Elikwu, C O Ezeamagu
BACKGROUND: Chronic rhinosinusitis (CRS) significantly lowers the quality of life of patients. The common use of broad spectrum antibiotics for its treatment may alter the pathogens that promote the persistence of this condition. However, the data concerning the distribution of bacteria species. in patients with CRS are not consistent. OBJECTIVE: To isolate the common aerobic and anaerobic bacteria from the middle meatal aspirates of adult patients with CRS and determine their antibiotic sensitivity patterns Methods: This was a case-control study of adults with diagnosis of CRS...
June 2016: African Journal of Medicine and Medical Sciences
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