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African Journal of Medicine and Medical Sciences

O A M Adesiyun, P O Adeoye, C K P Ofoegbu, E A O Afolayan
Chemodectoma, a neuroendocrine tumour of the paraganglionic cells in the carotid body remains an uncommon tumour. We report the first case from University of Ilorin Teaching Hospital, Ilorin, Nigeria. Though with a red herring history of trauma induced swelling, clinical and radiologic features were characteristic of chemodectoma. Histologic features of the excised lesion are presented.
December 2015: African Journal of Medicine and Medical Sciences
E O Adewoye, T E Adekeye, A O Ige
UNLABELLED: Abstract INTRODUCTION: Uncontrolled diabetes mellitus has been reported to lead to renal dysfunction. Quail egg consumption has been reported to exert curative effects in some disease conditions like diabetes mellitus, tuberculosis, and asthma. This study investigated the effects of quail egg consumption on some kidney functions in alloxan induced diabetic rats. METHODS: Forty male Wistar rats with an average weight of 170g were randomly divided into four groups...
December 2015: African Journal of Medicine and Medical Sciences
B M Gbadebo, R F Afolabi, A S Adebowale
BACKGROUND: Female Circumcision (FC) is a harmful traditional practice and remains a public health problem particularly in the era of HIV/AIDS. Aside its numerous health implications, it can cause infertility, complications in childbirth and increased risk of newborn deaths. FC is widely practised in Nigeria. OBJECTIVE: The study assessed the level of FC, daughters' circumcision and attitude towards discontinuation of the practice among women of reproductive age...
December 2015: African Journal of Medicine and Medical Sciences
T A Esan, E O Oziegbe
BACKGROUND: The World Health Organization in 1994 recommended that dental education should be problem based, socially and culturally relevant, and community oriented. OBJECTIVES: To explore the perceptions of Pre-phase II (pre-clinical II) dental students on three methods of teaching used during two academic sessions. METHODS: All part IV dental students in two consecutive sessions undergoing pre phase II course in the Faculty of Dentistry, Obafemi Awolowo University, Ile-Ife were recruited into the study...
December 2015: African Journal of Medicine and Medical Sciences
T O Babatunde, J O Ogunbiyi
BACKGROUND: Biliary tract carcinomas are uncommon but highly fatal malignancies. Most patients in our environment are diagnosed late and are not candidates for curative resection. OBJECTIVE: To determine the pattern and risk factors of biliary tract carcinoma in Ibadan. METHODOLOGY: This was a retrospective study of histologically confirmed cases of biliary tract carcinoma diagnosed at the University College Hospital, Ibadan between January 1971 and December 20 10...
December 2015: African Journal of Medicine and Medical Sciences
A T Salawu, S O Reis, O I Fawole, M D Dairo
BACKGROUND: Sexual behaviour among the youth contributes largely to the burden of reproductive health problems in Nigeria. This may have been worsened by the introduction of electronic media like internet and television (TV). However, little is known about the effects of electronic media on sexual behaviour of youth in Nigeria. Therefore, exploring the influence of effect of electronic media on sexual behaviour of youth may help policy maker to provide interventions to these problems...
December 2015: African Journal of Medicine and Medical Sciences
O K Moyib, O Falegbe, F R Moyib
BACKGROUND: The present study estimated nutrient composition of walnuts before and after cooking with respect to its potential as valuable source of nutrients for daily intake. METHOD: Walnut fruits were purchased from five different markets in Ijebu-Ode local government area and its environs. The fruits samples were divided into two portions, labelled R (for raw) and C (cooked). The C samples were cooked at 100 degrees C for 1 hr and allowed to cool to room temperature...
December 2015: African Journal of Medicine and Medical Sciences
K A Akinlade, J O Akinyemi, O I Fawole
BACKGROUND: In Nigeria, self-medication of young children is common. Children under the age of five are often self-medicated with antibiotics because of their increased susceptibility to infections. OBJECTIVES: To assess mothers' knowledge on the hazards of antibiotics self-medication in a rural community of South-west Nigeria. METHODOLOGY: A community-based, cross-sectional study was conducted among 513 mothers selected through a purposive sampling technique from Koko community in Olodo, Ibadan between October and December, 2014...
December 2015: African Journal of Medicine and Medical Sciences
OA Sowande, Ao Talabi, Sa Olowookere, Adejuyigbe, Fj Owotade
BACKGROUND: HIV exposed children could require surgical procedures when ill. This study assessed how paediatric HIV/AIDS affected surgical practice among Nigerian paediatric surgeons. METHODS: Descriptive cross-sectional study among consenting paediatric surgeons completing a self-administered questionnaire on the current practices and perception on HIV/AIDS in relation to their surgical practice. Data were analyzed using descriptive and inferential statistics. RESULTS: Thirty eight out of forty two copies of questionnaire distributed were completed and included in analysis giving a response rate of 92...
December 2015: African Journal of Medicine and Medical Sciences
F S Oluwole
Peptic ulcer disease is a multi-factorial disorder of the gastrointestinal tract with a global prevalence affecting about 4.6 million people annually and having a mortality of one death per 10,000 cases. Helicobacter pylori (H. pylori) plays a profound role in the pathogenesis of chronic gastritis, peptic ulcer, including gastric mucosa-associated lymphoid tissue and carcinoma. Any compromise to the gastric mucosal barrier will greatly affect the integrity of the stomach. H. pylori is an organism which mediates a compromise of the gastric mucosal barrier by stimulating increased gastric acid secretion, causing alteration of certain immune factors, penetration of the mucosal layer and provoking persistent inflammation even without invading the mucus membrane...
December 2015: African Journal of Medicine and Medical Sciences
A Ogunniyi
No abstract text is available yet for this article.
December 2015: African Journal of Medicine and Medical Sciences
A O Ifesanya, O J Ogundele, A A Anejukwo
BACKGROUND: Bilateral posterior dislocation of the shoulders is rare and may result from a seizure. A 48 year-old HIV-positive man who presented eight weeks after bilateral posterior shoulder dislocation and bilateral fractures of the surgical necks of both humeri is reviewed. He was treated with an algesics and physiotherapy and was able to return to work after 9 months. CONCLUSION: The rarity of this lesion, its late presentation, the importance of a high index of suspicion in making the diagnosis and the fair outcome of non-operative treatment informed this report...
September 2015: African Journal of Medicine and Medical Sciences
O A Adetunji, N F Adigun, M A Odeniyi
BACKGROUND: This study was undertaken with the objective of evaluating the pharmaceutical and chemical equivalence of some commercially available loratadine tablets, and offers a possible explanation for the therapeutic failure of the drug products. METHOD: The equivalence of eight brands of loratadine hydrochloride tablets labelled A to H was assessed and compared with the Innovator brand labelled I. Visual observation and uniformity of weight tests were carried out on the tablets, mechanical properties were assessed using friability and crushing strength tests as parameters...
September 2015: African Journal of Medicine and Medical Sciences
E O Adewoye, B O Adele
BACKGROUND: Increased generation of free radicals from protein glycation has been associated with compromised integrity of erythrocytes in diabetes. Musa sapientum has been reported to possess anti-diabetic properties and this study investigated the effect of methanol extract of Musa sapientum on protein glycation and erythrocyte integrity. METHODS: Forty-two male Wistar rats (180-200g) were randomly grouped into seven: 1 (control), 2 (diabetic untreated), 3 (normal extract-treated (250 mg/kg)), 4 (normal metformin-treated (150 mg/kg)), 5 (diabetic extract-treated (250 mg/kg)), 6 (diabetic metformin-treated (150 mg/kg)), 7 (diabetic insulin-treated (1 IU/kg))...
September 2015: African Journal of Medicine and Medical Sciences
S A Onasanwo, J A Adeyemi, G G Latinwo, S O Faborode, V Mishra
BACKGROUND: Nevirapine is a very potent antiretroviral drug frequently used in the management of Human Immunodeficiency Virus (HIV). Opportunistic pathologies in HIV/AIDS patients include gastric ulcer and gastrointestinal haemorrhage. Hence, the impact of nevirapine on induced gastric ulcer was studied using Wistar rats. METHODS: Anti-ulcer activity of nevirapine was evaluated using cold restraint stress-induced, ethanol-induced and pylorus ligation-induced gastric ulcer models for acute ulceration; and acetic acid-induced ulcer model for the chronic ulceration in Wistar rats...
September 2015: African Journal of Medicine and Medical Sciences
A E Orimadegun, A O Alohan, S Onazi
UNLABELLED: Abstract BACKGROUND: Haemoglobin desaturation, which presents as hypoxaemia, is a known phenomenon in the cycle of red blood cells sickling in sickle cell anaemia (SCA). Thus, early and accurate recognition of hypoxaemia is important in order to ameliorate its adverse effects on vital organs. This study was carried out to investigate clinical and laboratory features that predict hypoxaemia in children with SCA during steady-state. METHODS: We prospectively measured percutaneous haemoglobin saturation of 208 children with SCA in room air during steady-state at a secondary health facility in the north-west of Nigeria...
September 2015: African Journal of Medicine and Medical Sciences
B A Olusanya, M O Ugalahi, C E Okoli, A M Baiyeroju
BACKGROUND: The prevalence and burden of amblyopia in developing countries is probably underestimated, and little is known about the pattern of amblyopia in West Africa. AIM: To determine the relative frequency and types of amblyopia among children with refractive errors seen in the eye clinic of a tertiary hospital over a 2 year period. METHODS: A cross-sectional study conducted at the eye clinic of the University College Hospital, Ibadan, Nigeria between January 2012 and December 2013...
September 2015: African Journal of Medicine and Medical Sciences
B V Owoyele, A L Oyewole, S A Biliaminu, Y Alashi
BACKGROUND: Caffeine is a component of several beverages such as coffee and tea. It has been shown to possess psychoactive properties because it increases alertness, energy and ability to concentrate at moderate doses. Taurine on the other hand, is an amino acid which has the capacity to promote neural development, osmoregulation and neuroprotection. There is paucity of information on the effect of the combined administration of taurine and caffeine on C-reactive protein (CRP)--a marker of inflammation and plasma calcium level in rats...
September 2015: African Journal of Medicine and Medical Sciences
S A Bamigboye, O O Dosumu, D M Ajayi
BACKGROUND: Oral environment is not sterile, and dentures worn by the patients can be infected and therefore needs disinfection. Solution disinfectants such as sodium hypochlorite and glutaraldehyde can be used but they have side effects. Microwave disinfection method is more recent, however, there are conflicting reports at the moment on the appropriate power and time regimen for disinfection of denture. OBJECTIVE: To determine the power and time regimen at which the disinfection of dentures can be achieved using microwave...
September 2015: African Journal of Medicine and Medical Sciences
G F Ibironke, O G Modupe
BACKGROUND: This study investigated the mechanism of Ocimum gratissimum induced neurobehavioural alterations in mice. The plant is widely consumed in most parts of the world including Nigeria where it is used as a spice and phytomedicine by alternate medical practitioners. METHODS: The animals were divided into three groups of six mice each. Control and Ocimum gratissum treated mice were subjected to the hole-board, light/dark box, elevated plus maze and open field tests...
September 2015: African Journal of Medicine and Medical Sciences
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