Read by QxMD icon Read

Early Human Development

Joanne M George, Simona Fiori, Jurgen Fripp, Kerstin Pannek, Andrea Guzzetta, Michael David, Robert S Ware, Stephen E Rose, Paul B Colditz, Roslyn N Boyd
AIM: This study aimed to examine associations between structural MRI and concurrent motor, neurological and neurobehavioral measures at 30-32 weeks postmenstrual age (PMA; 'Early'), and at term equivalent age ('Term'). METHOD: In this prospective cohort study, infants underwent Early MRI (n = 119; 73 male; median 32 weeks 1 day PMA) and Term MRI (n = 102; 61 male; median 40 weeks 4 days PMA) at 3 T. Structural images were scored generating white matter (WM), cortical gray matter, deep gray matter, cerebellar and global brain abnormality scores...
January 13, 2018: Early Human Development
Victor Grech
Data analysis at the descriptive stage and the eventual presentation of results requires the tabulation and summarisation of data. This exercise should always precede inferential statistics. Pivot tables and pivot charts are one of Excel's most powerful and underutilised features, with tabulation functions that immensely facilitate descriptive statistics. Pivot tables permit users to dynamically summarise and cross-tabulate data, create tables in several dimensions, offer a range of summary statistics and can be modified interactively with instant outputs...
January 12, 2018: Early Human Development
Victor Grech
Plotting data into graphs is a crucial step in data analysis as part of an initial descriptive statistics exercise since it gives the researcher an overview of the shape and nature of the data. Outlier values may also be identified, and these may be incorrect data, or true and important outliers. This paper explains how to access Microsoft Excel's Analysis Toolpak and provides some pointers for the utilisation of the histogram tool within the Toolpak.
January 12, 2018: Early Human Development
Gareth Richards, Magdalena Klimek, Grazyna Jasienska, Urszula M Marcinkowska
BACKGROUND: Digit ratio (2D:4D) is used by researchers as an indicator of prenatal sex hormone exposure. Two previous studies have examined associations between 2D:4D and circulating sex steroid concentrations across the menstrual cycle in adult females. One reported that digit ratio correlated positively with oestradiol levels, whereas the other found no such effect; neither observed significant associations with progesterone. AIMS: To examine associations between 2D:4D, as well as asymmetry (i...
January 8, 2018: Early Human Development
Sebastian Pfahl, Thomas Hoehn, Klaus Lohmeier, Renate Richter-Werkle, Florian Babor, Dirk Schramm, Hemmen Sabir
No abstract text is available yet for this article.
January 5, 2018: Early Human Development
Natalie Fairbairn, Claire Galea, Alison Loughran-Fowlds, Antoinette Hodge, Nadia Badawi, Karen Walker
BACKGROUND: Previous predictive research has predominantly focussed on infants who are preterm, low birth weight, who have a specific condition or who have undergone a specific procedure. AIM: This study investigated the ability of outcomes at one year of age to predict outcomes at three years using the Bayley-III for infants who have undergone early major cardiac surgery (CS) or non-cardiac (NC) surgery and their healthy peers. STUDY DESIGN: Participants who were part of the Development After Infant Surgery (DAISy) study who had complete Bayley-III assessments at one and three years of age were included in the analyses...
December 27, 2017: Early Human Development
M P H Koster, L van Duijn, Y H M Krul-Poel, J S Laven, W A Helbing, S Simsek, R P M Steegers-Theunissen
BACKGROUND: Interactions between genetic and environmental factors, including modifiable maternal nutrition and lifestyle, play a significant role in the pathogenesis of most congenital heart defects (CHD). The aim of this study was to investigate associations between periconceptional maternal vitamin D status and the prevalence of CHD in offspring. METHODS: A case-control study was performed in 345 mothers of a child with CHD and 432 mothers of a child without CHD from four tertiary hospitals in the Netherlands between 2003 and 2005...
December 26, 2017: Early Human Development
Yuliya S Krivova, Alexandra E Proshchina, Valeriy M Barabanov, Irina V Barinova, Sergey V Saveliev
BACKGROUND: Expression of the intermediate filament protein vimentin has been recently observed in the pancreatic islet β- and α-cells of humans with type 2 diabetes mellitus. It was suggested that the presence of vimentin in endocrine cells may indicate islet tissue renewal, or potentially represent the dedifferentiation of endocrine cells, which could contribute to the onset of type 2 diabetes or islet cell dysfunction. AIM: To analyze the expression of vimentin in pancreatic β- and α-cells of macrosomic infants of diabetic and nondiabetic mothers...
December 21, 2017: Early Human Development
S van Veen, C S H Aarnoudse-Moens, J Oosterlaan, L van Sonderen, T R de Haan, A H van Kaam, A G van Wassenaer-Leemhuis
AIM: To explore changes in motor and cognitive outcomes in very preterm (VP; gestational age<30weeks) born children between ages five and six years, and to determine whether changes in these outcomes were associated with the use of healthcare therapies and educational provisions. STUDY DESIGN: Single-center observational cohort study. Five-year-old VP born children of a one-year-cohort of our neonatal follow-up program (N=90) were invited for re-assessments at age six...
December 21, 2017: Early Human Development
Roberta Pineda, Joy Bender, Bailey Hall, Lisa Shabosky, Anna Annecca, Joan Smith
OBJECTIVE: To 1) define predictors of parent presence, any holding, holding in arms, and skin-to-skin care in the NICU and 2) investigate the relationships between parent participation and a) early neurobehavior and b) developmental outcomes at age 4 to 5years among preterm infants. METHODS: Eighty-one preterm infants born ≤32weeks estimated gestational age were prospectively enrolled within one week of life in a level III-IV NICU. Parent (maternal and paternal) presence and holding (including holding in arms and skin-to-skin care) were tracked throughout NICU hospitalization...
December 21, 2017: Early Human Development
David P Laplante, Kimberley J Hart, Michael W O'Hara, Alain Brunet, Suzanne King
No abstract text is available yet for this article.
December 15, 2017: Early Human Development
Inês Baía, Mariana Amorim, Susana Silva, Michelle Kelly-Irving, Cláudia de Freitas, Elisabete Alves
No abstract text is available yet for this article.
December 14, 2017: Early Human Development
Tinka Bröring, Marsh Königs, Kim J Oostrom, Harrie N Lafeber, Anniek Brugman, Jaap Oosterlaan
BACKGROUND: Very preterm birth has a detrimental impact on the developing brain, including widespread white matter brain abnormalities that threaten efficient sensory processing. Yet, sensory processing difficulties in very preterm children are scarcely studied, especially at school age. AIMS: To investigate somatosensory registration, multisensory integration and sensory modulation. PARTICIPANTS: 57 very preterm school-age children (mean age=9...
December 8, 2017: Early Human Development
Victor Grech
INTRODUCTION: Stress reduces the male to female ratio at birth (M/T). China's Great Leap Forward (11/1957-1/1961) had disastrous consequences with a catastrophic national famine that lasted between 1959 and 1961. This resulted in a reduction in births and an additional male birth deficit. This study was carried out in order to estimate the total pregnancy losses and M/T, along with these value's perinatal mortality rates equivalents. METHODS: Estimated M/T and births for 1956-61 and for the aggregates of 1956-58 and 1959-61 were calculated...
December 8, 2017: Early Human Development
Charlotte V Farewell, Zaneta M Thayer, Jini E Puma, Susan Morton
No abstract text is available yet for this article.
December 7, 2017: Early Human Development
Mario Motta, Brunetta Guaragni, Elena Pezzotti, Carmen Rodriguez-Perez, Gaetano Chirico
No abstract text is available yet for this article.
December 7, 2017: Early Human Development
Stefano Ghirardello, Genny Raffaeli, Giacomo Cavallaro, Fabio Mosca
No abstract text is available yet for this article.
December 7, 2017: Early Human Development
Martha L Velez, Krystle McConnell, Nancy Spencer, Lina Montoya, Michelle Tuten, Lauren M Jansson
No abstract text is available yet for this article.
December 7, 2017: Early Human Development
Daniela Testoni, Christoph P Hornik, Ruth Guinsburg, Reese H Clark, Rachel G Greenberg, Daniel K Benjamin, P Brian Smith
BACKGROUND: Lumbar puncture (LP) is the gold standard for diagnosing meningitis; however it is unknown whether early LP (≤3days of life) is associated with increased risk of intraventricular hemorrhage (IVH) in very low birth weight (VLBW) infants. OBJECTIVE: To determine whether early LP in VLBW infants is associated with severe IVH. METHODS: VLBW infants from a cohort of 1,158,789 infants discharged from 382 neonatal intensive care units (1997-2015) were enrolled...
December 5, 2017: Early Human Development
Victor Grech
The sex ratio at birth may be depressed by a variety of events or conditions due to an excess of male foetal losses. Evidence is accumulating that observed differences in this ratio between races, nations and even at regional global level, may be due to socio-economic stress. This review summarises findings pertaining to Blacks in the United States, and to a global United Nations dataset. Extant evidence reinforces the theory that chronic socio-economic stress may be the reason for a lower birth sex ratio at racial, national and global levels...
December 4, 2017: Early Human Development
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"