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Early Human Development

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https://www.readbyqxmd.com/read/28431256/neurodevelopmental-outcomes-of-neonates-undergoing-surgery-under-general-anesthesia-for-malrotation-of-intestines
#1
Suresh Birajdar, Shripada Rao, Judy McMichael
BACKGROUND: It is difficult to differentiate between the potential adverse effects of general anesthesia (GA) on the developing brain and the role of associated co-morbidities and syndromes that can adversely affect neurodevelopmental outcomes in neonates undergoing GA. Neonates with malrotation of the intestines without volvulus usually do not have co-morbidities or syndromes. In addition, majority of them recover very well after surgery and are discharged home within a few days. Neonates with malrotation are a clean cohort of babies to study the role of a single episode of GA on the developing brain...
April 18, 2017: Early Human Development
https://www.readbyqxmd.com/read/28431255/do-orally-directed-behaviors-mediate-the-relationship-between-behavioral-state-and-nutritive-sucking-in-preterm-infants
#2
Rosemary White-Traut, Li Liu, Kathleen Norr, Krisitin Rankin, Suzann K Campbell, Thao Griffith, Rohitkumar Vasa, Victoria Geraldo, Barbara Medoff-Cooper
No abstract text is available yet for this article.
April 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28426979/response-based-sleep-intervention-helping-infants-sleep-without-making-them-cry
#3
Wendy Middlemiss, Helen Stevens, Lael Ridgway, Susan McDonald, Michelle Koussa
No abstract text is available yet for this article.
April 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28426948/digit-ratio-2d-4d-and-handgrip-strength-are-correlated-in-women-but-not-in-men-in-hui-ethnicity
#4
Hong Lu, Dan Shen, Lu Wang, Shibo Niu, Chunyue Bai, Zhanbing Ma, Zhenghao Huo
INTRODUCTION: Digit ratio, especially second-to-fourth digit ratio (2D:4D) is used as a biomarker of prenatal testosterone exposure and was found associated with physical ability, such as handgrip strength (HGS). Recently, this association has been discussed in several ethnic groups. AIMS: To investigate correlations between 2D:4D and HGS in Chinese population of Ningxia Hui ethnicity. METHODS: Here we firstly present the evidence on digit ratio and HGS of 346 college students (119 males and 227 females) by collecting photographs and HGS of both hands at Yinchuan city, in the Ningxia province of China...
April 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28411449/prenatal-concentrations-of-perfluoroalkyl-substances-and-early-communication-development-in-british-girls
#5
Zuha Jeddy, Terryl J Hartman, Ethel V Taylor, Cayla Poteete, Katarzyna Kordas
Perfluoroalkyl substances (PFAS), found in many household products and classed as endocrine disrupting chemicals, can be transferred through the placenta and are associated with multiple developmental deficits in offspring. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC), we investigated the association between intrauterine exposure to PFAS and early communication development in 432 mother-daughter dyads at 15 and 38months of age. Concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), perfluorohexane sulfonate (PFHxS), and perfluorononanoate (PFNA) were measured in maternal serum collected during pregnancy...
April 12, 2017: Early Human Development
https://www.readbyqxmd.com/read/28399458/the-role-of-maternal-anxiety-and-depressive-disorders-prior-to-and-during-pregnancy-and-perinatal-psychopathological-symptoms-for-early-infant-diseases-and-drug-administration
#6
Linda Krause, Franziska Einsle, Johanna Petzoldt, Hans-Ulrich Wittchen, Julia Martini
BACKGROUND: Maternal mental health prior to and during pregnancy has been shown to be associated with inflammatory diseases and gastrointestinal complaints in the offspring. Unfortunately, many studies merely focused on perinatal distress without consideration of lifetime anxiety and depressive disorders. AIMS: To prospectively investigate associations of anxiety and depressive disorders prior to and during pregnancy as well as perinatal distress with infants' inflammatory diseases, gastrointestinal complaints and corresponding drug administration...
April 8, 2017: Early Human Development
https://www.readbyqxmd.com/read/28399457/cumulative-pain-related-stress-and-developmental-outcomes-among-low-risk-preterm-infants-at-one-year-corrected-age
#7
Iris Morag, Ifat Rotem, Mor Frisch, Israel Hendler, Michal J Simchen, Leah Leibovitz, Ayala Maayan-Metzger, Tzipora Strauss
BACKGROUND: Extensive exposure of preterm infants to pain-related stress (PRS) at a time of physiological immaturity and rapid brain development may contribute to altered neurodevelopment. OBJECTIVE: To examine the relationship between early PRS and neurodevelopmental outcomes among low-risk very preterm infants at the age of one year corrected age (CA). METHODS: Participants included 107 infants born <32weeks gestational age (GA) and monitored prospectively at 12...
April 8, 2017: Early Human Development
https://www.readbyqxmd.com/read/28391117/delivery-and-feeding-mode-affects-fecal-calprotectin-levels-in-infants-7months-old
#8
Yoo Mi Lee, Chae-Yeon Min, You Jin Choi, Su Jin Jeong
BACKGROUND: Elevated fecal calprotectin (FC) is a non-invasive marker of inflammation indicating bowel disease. However, healthy infants have displayed high FC levels, with large variation. We sought to determine what factors might affect FC levels in children <6months old. METHODS: We recruited 133 healthy infants aged 0-6months from four Korean day care centers. Stool samples were analyzed by immunosorbent assay. All infants completed a questionnaire related to clinical characteristics including birth and feeding history...
April 6, 2017: Early Human Development
https://www.readbyqxmd.com/read/28390243/neonatal-neurological-examination-during-the-first-6h-after-birth
#9
Domenico M Romeo, Sarah Bompard, Carmen Cocca, Francesca Serrao, Maria Pia De Carolis, Antonio A Zuppa, Daniela Ricci, Francesca Gallini, Chiara Maddaloni, Costantino Romagnoli, Eugenio Mercuri
BACKGROUND: Few neurological assessments are easily performed during the first 6h after birth. AIMS: To assess a cohort of low risk term born newborns within the first 6h and at 48h after birth using the Hammersmith Neonatal Neurological Examination. STUDY DESIGN AND SUBJECTS: A population of low risk term born newborns was examined within 3h from birth or between 3 and 6h. Each infant was re-assessed at 48h, establishing the range and frequency distribution of neonatal neurological scores at each time point...
April 5, 2017: Early Human Development
https://www.readbyqxmd.com/read/28388489/serial-measures-of-cardiac-performance-using-tissue-doppler-imaging-velocity-in-preterm-infants-29weeks-gestations
#10
Colm R Breatnach, Afif El-Khuffash, Adam James, Naomi McCallion, Orla Franklin
INTRODUCTION: Tissue Doppler imaging (TDI) is a useful marker of myocardial performance in preterm infants. We aimed to demonstrate serial changes in TDI velocity in preterm infants <29weeks gestation, to assess the impact of inotropes and a haemodynamically significant patent ductus arteriosus (hsPDA). METHODS: This was a prospective observational study of preterm infants <29weeks gestation. Echocardiography was performed at days 1, 2, 5-7 and at 36weeks, or before hospital discharge...
April 4, 2017: Early Human Development
https://www.readbyqxmd.com/read/28371672/determinants-of-pulmonary-dead-space-in-ventilated-newborn-infants
#11
Theodore Dassios, Ourania Kaltsogianni, Anne Greenough
BACKGROUND: Pulmonary dead space (VD) is an index of ventilation inhomogeneity and one of the determinants of the magnitude of tidal volume to maintain optimal blood gases. AIMS: To identify the determinants of VD in ventilated newborns and to investigate differences in VD between prematurely born and term infants and those prematurely born infants who did or did not develop bronchopulmonary dysplasia (BPD). METHODS: Sixty-one mechanically ventilated infants (15 term, 46 preterm) were studied at a median age of 8 (IQR 2-31) days; 32 of the preterm infants developed BPD...
March 31, 2017: Early Human Development
https://www.readbyqxmd.com/read/28364636/associations-of-maternal-obesity-and-excessive-weight-gain-during-pregnancy-with-subcutaneous-fat-mass-in-infancy
#12
Varsha V Jharap, Susana Santos, Eric A P Steegers, Vincent W V Jaddoe, Romy Gaillard
BACKGROUND: Not much is known about the associations of maternal obesity and excessive gestational weight gain with body fat in infancy. OBJECTIVE: To examine the associations of maternal pre-pregnancy body mass index and gestational weight gain with infant subcutaneous fat. METHODS: In a population-based prospective cohort study among 845 mothers and their infants, we obtained maternal pre-pregnancy body mass index and measured maternal weight during pregnancy...
March 29, 2017: Early Human Development
https://www.readbyqxmd.com/read/28347592/a-review-of-the-established-and-suspected-causes-of-variations-in-human-sex-ratio-at-birth
#13
William H James, Victor Grech
The human sex ratio (proportion male) at birth (SRB) varies with many variables. Some of this variation has an established proximate cause. For instance, low SRB (more females) at birth are associated with various forms of stressful events or circumstances during or prior to pregnancy. These low SRB are almost certainly mainly caused by maternal-stress-induced male foetal loss. Other types of SRB variation are thought to be caused by hormonal variation in either or both parents around the time of conception...
March 24, 2017: Early Human Development
https://www.readbyqxmd.com/read/28347591/variability-of-late-and-moderate-preterm-definitions
#14
LETTER
Shilpi Chabra
No abstract text is available yet for this article.
March 24, 2017: Early Human Development
https://www.readbyqxmd.com/read/28343092/the-impact-of-cumulative-pain-stress-on-neurobehavioral-development-of-preterm-infants-in-the-nicu
#15
Xiaomei Cong, Jing Wu, Dorothy Vittner, Wanli Xu, Naveed Hussain, Shari Galvin, Megan Fitzsimons, Jacqueline M McGrath, Wendy A Henderson
BACKGROUND: Vulnerable preterm infants experience repeated and prolonged pain/stress stimulation during a critical period in their development while in the neonatal intensive care unit (NICU). The contribution of cumulative pain/stressors to altered neurodevelopment remains unclear. The study purpose was to investigate the impact of early life painful/stressful experiences on neurobehavioral outcomes of preterm infants in the NICU. METHODS: A prospective exploratory study was conducted with fifty preterm infants (28 0/7-32 6/7weeks gestational age) recruited at birth and followed for four weeks...
March 23, 2017: Early Human Development
https://www.readbyqxmd.com/read/28343091/rapid-detection-and-ruling-out-of-neonatal-sepsis-by-pcr-coupled-with-electrospray-ionization-mass-spectrometry-pcr-esi-ms
#16
Cristina Delcò, Oliver Karam, Riccardo Pfister, Alain Gervaix, Gesuele Renzi, Stéphane Emonet, Jacques Schrenzel, Klara M Posfay-Barbe
BACKGROUND: Sepsis is an important cause of morbidity and mortality in neonates and clinicians are typically required to administer empiric antibiotics while waiting for blood culture results. However, prolonged and inappropriate use of antibiotics is associated with various complications and adverse events. Better tools to rapidly rule out bacterial infections are therefore needed. AIMS: We aimed to assess the negative predictive value of PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS) compared to conventional blood cultures in neonatal sepsis...
March 23, 2017: Early Human Development
https://www.readbyqxmd.com/read/28342569/corrigendum-to-an-emerging-evidence-base-for-the-management-of-neonatal-hypoglycemia-early-hum-dev-2017-104-51-56
#17
J E Harding, D L Harris, J E Hegarty, J M Alsweiler, C J McKinlay
No abstract text is available yet for this article.
March 23, 2017: Early Human Development
https://www.readbyqxmd.com/read/28342385/follow-up-at-two-years-of-age-and-early-predictors-of-non-compliance-in-a-cohort-of-very-preterm-infants
#18
Claire Mas, Patrick Gérardin, Emmanuel Chirpaz, Magali Carbonnier, Corinne Mussard, Sylvain Samperiz, Duksha Ramful
AIM: To examine the rates of follow-up at two years of age and perinatal factors associated with non-compliance in an observational population-based cohort of very preterm children enrolled in a routine follow-up program. METHOD: Data review of infants born between 2008 and 2012 in the Observatoire de La Grande Prématurité, Reunion Island cohort. All singletons born alive before 33weeks of gestational age and resident on the island at two years of age were included...
March 22, 2017: Early Human Development
https://www.readbyqxmd.com/read/28282531/bone-fracture-in-severe-small-for-gestational-age-extremely-low-birth-weight-infants-a-single-center-analysis
#19
Hidehiko Maruyama, Shoichiro Amari, Hideshi Fujinaga, Shuhei Fujino, Junko Nagasawa, Yuka Wada, Keiko Tsukamoto, Yushi Ito
INTRODUCTION: Bone fracture is a complication of extremely low birth weight infants (ELBWIs). This study aimed to analyze risk factors for bone fracture in a population of severe small-for-gestational-age (SGA) ELBWIs. METHODS: We retrospectively studied data from ELBWIs with a birth weight <1000g and <-2 standard deviations (SDs) born at the National Center for Child Health and Development, Japan, from 2013 to 2015. Infants were divided into fracture and control groups...
March 2017: Early Human Development
https://www.readbyqxmd.com/read/28282530/effect-of-early-intervention-on-functional-outcome-at-school-age-follow-up-and-process-evaluation-of-a-randomised-controlled-trial-in-infants-at-risk
#20
Elisa G Hamer, Tjitske Hielkema, Arend F Bos, Tineke Dirks, Siebrigje J Hooijsma, Heleen A Reinders-Messelink, Rivka F Toonen, Mijna Hadders-Algra
BACKGROUND: The long-term effect of early intervention in infants at risk for developmental disorders is unclear. The VIP project (n=46, originally) evaluated by means of a randomised controlled trial the effect of the family centred early intervention programme COPCA (Coping with and Caring for infants with special needs) in comparison to that of traditional infant physiotherapy (TIP). AIMS: To evaluate the effect of early intervention on functional outcome at school age...
March 2017: Early Human Development
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