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Early Human Development

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https://www.readbyqxmd.com/read/28282531/bone-fracture-in-severe-small-for-gestational-age-extremely-low-birth-weight-infants-a-single-center-analysis
#1
Hidehiko Maruyama, Shoichiro Amari, Hideshi Fujinaga, Shuhei Fujino, Junko Nagasawa, Yuka Wada, Keiko Tsukamoto, Yushi Ito
INTRODUCTION: Bone fracture is a complication of extremely low birth weight infants (ELBWIs). This study aimed to analyze risk factors for bone fracture in a population of severe small-for-gestational-age (SGA) ELBWIs. METHODS: We retrospectively studied data from ELBWIs with a birth weight <1000g and <-2 standard deviations (SDs) born at the National Center for Child Health and Development, Japan, from 2013 to 2015. Infants were divided into fracture and control groups...
March 7, 2017: Early Human Development
https://www.readbyqxmd.com/read/28282530/effect-of-early-intervention-on-functional-outcome-at-school-age-follow-up-and-process-evaluation-of-a-randomised-controlled-trial-in-infants-at-risk
#2
Elisa G Hamer, Tjitske Hielkema, Arend F Bos, Tineke Dirks, Siebrigje J Hooijsma, Heleen A Reinders-Messelink, Rivka F Toonen, Mijna Hadders-Algra
BACKGROUND: The long-term effect of early intervention in infants at risk for developmental disorders is unclear. The VIP project (n=46, originally) evaluated by means of a randomised controlled trial the effect of the family centred early intervention programme COPCA (Coping with and Caring for infants with special needs) in comparison to that of traditional infant physiotherapy (TIP). AIMS: To evaluate the effect of early intervention on functional outcome at school age...
March 1, 2017: Early Human Development
https://www.readbyqxmd.com/read/28282529/evidence-of-socio-economic-stress-and-female-foeticide-in-racial-disparities-in-the-gender-ratio-at-birth-in-the-united-states-1995-2014
#3
Victor Grech
BACKGROUND: Males are born in excess of females, expressed as M/T (male/total births), which is expected to approximate 0.515. Racial M/T disparities have been long known. This study was carried out in order to identify such disparities in different races in the United States. DESIGN: Monthly male and female live births by race for the entire US were obtained from the website of the Centers for Disease Control and Prevention for 1995-2014 for the four racial groups: American Indian or Alaska Native, Asian or Pacific Islander, Black or African American and White...
March 1, 2017: Early Human Development
https://www.readbyqxmd.com/read/28199954/effects-of-single-family-rooms-on-nurse-parent-and-nurse-infant-interaction-in-neonatal-intensive-care-unit
#4
Mirka Toivonen, Liisa Lehtonen, Eliisa Löyttyniemi, Anna Axelin
BACKGROUND: Single-family rooms in neonatal intensive care unit can provide longer interaction between family and staff. On the other hand, separation in private rooms has been shown detrimental to child development if parents are not present. AIMS: To examine the effects of single-family rooms on nurse-family, nurse-parent and nurse-infant interaction time in neonatal intensive care unit. STUDY DESIGN: A quantitative, comparative, observational study was conducted before and after a move to a neonatal intensive care unit with single-family rooms...
February 12, 2017: Early Human Development
https://www.readbyqxmd.com/read/28193574/effects-of-preterm-birth-and-fetal-growth-retardation-on-life-course-cardiovascular-risk-factors-among-schoolchildren-from-colombia-the-fuprecol-study
#5
Robinson Ramírez-Vélez, Jorge Enrique Correa-Bautista, Emilio Villa-González, Javier Martínez-Torres, Anthony C Hackney, Antonio García-Hermoso
BACKGROUND: Both fetal growth restriction and prematurity have been associated with cardiometabolic risk in youth and adults, however, data on their combined effects on cardiometabolic health in youth are scarce. AIMS: This study aimed at assessing the effects of birth weight and gestational age combined on life-course cardiovascular risk factors and obesity among schoolchildren from Colombia. STUDY DESIGN: A cross-sectional study. SUBJECTS: Participants comprised 2510 Colombian schoolchildren (54...
February 10, 2017: Early Human Development
https://www.readbyqxmd.com/read/28189798/preterm-infant-development-maternal-distress-and-sensitivity-the-influence-of-severity-of-birth-weight
#6
Erica Neri, Francesca Agostini, Franco Baldoni, Elisa Facondini, Augusto Biasini, Fiorella Monti
OBJECTIVE: To evaluate the influence of the severity of prematurity based on birth weight on maternal distress and sensitivity and on infant development. METHODS: Sixty-eight mothers and their preterm babies (30 babies classified into Extremely-Low-Birth Weight-ELBW and 38 into Very-Low-Birth Weight-VLBW) were assessed at 9months of infant corrected age, using: Griffiths Scales for infant development, CARE-Index for maternal sensitivity during 5-minute of mother-infant interaction, and Parenting Stress Index-Short Form (PSI-SF) for maternal distress...
February 9, 2017: Early Human Development
https://www.readbyqxmd.com/read/28189001/functional-outcome-at-school-age-of-children-born-with-gastroschisis
#7
Chiara C M M Lap, Sandra W Bolhuis, Koenraad N J A Van Braeckel, Sijmen A Reijneveld, Gwendolyn T R Manten, Arend F Bos, Jan B F Hulscher
OBJECTIVE: We aimed to determine motor, cognitive and behavioural outcomes of school aged children born with gastroschisis compared to matched controls. STUDY DESIGN: We compared outcomes of 16 children born with gastroschisis treated at the University Medical Center Groningen, the Netherlands, between 1999 and 2006 with 32 controls matched for gender, gestational age, birth weight, and corrected for small for gestational age (SGA) and parental socioeconomic status (SES)...
February 8, 2017: Early Human Development
https://www.readbyqxmd.com/read/28189000/breast-milk-retinol-concentration-in-mothers-of-preterm-newborns
#8
Mayara Santa Rosa Lima, Karla Danielly da Silva Ribeiro, Jeane Franco Pires, Dalila Fernandes Bezerra, Paula Emília Nunes Ribeiro Bellot, Luana Patrícia de Oliveira Weigert, Roberto Dimenstein
BACKGROUND: Preterm newborns have low vitamin A reserves at birth, which increases their risk of morbidity and mortality. In the absence of supplementation, breast milk is the only source of this nutrient for exclusively breastfed infants. AIMS: To assess retinol concentration in preterm milk and the relationship between this retinol concentration and lactation phase, degree of prematurity, and maternal serum retinol level. STUDY DESIGN: Longitudinal study...
February 7, 2017: Early Human Development
https://www.readbyqxmd.com/read/28187337/brain-morphology-in-school-aged-children-with-prenatal-opioid-exposure-a-structural-mri-study
#9
Eivind Sirnes, Leif Oltedal, Hauke Bartsch, Geir Egil Eide, Irene B Elgen, Stein Magnus Aukland
BACKGROUND: Both animal and human studies have suggested that prenatal opioid exposure may be detrimental to the developing fetal brain. However, results are somewhat conflicting. Structural brain changes in children with prenatal opioid exposure have been reported in a few studies, and such changes may contribute to neuropsychological impairments observed in exposed children. AIM: To investigate the association between prenatal opioid exposure and brain morphology in school-aged children...
February 7, 2017: Early Human Development
https://www.readbyqxmd.com/read/28183002/unconjugated-free-bilirubin-in-preterm-infants
#10
Lori W E van der Schoor, Peter H Dijk, Henkjan J Verkade, Anna C J Kamsma, Andrea B Schreuder, Henk Groen, Christian V Hulzebos
BACKGROUND: Hyperbilirubinemia guidelines are based on total serum bilirubin (TSB), in combination with either gestational age (GA) or birth weight (BW), postnatal age and specific risk factors. However, TSB is a poor predictor of bilirubin-induced neurotoxicity (BIND). Free unconjugated bilirubin (UCBfree) and the UCBfree/TSB ratio are more directly related to BIND, but data on their postnatal courses are unknown. AIMS: To characterize the postnatal courses of UCBfree and UCBfree/TSB ratio, and assess their relationships with clinical characteristics...
February 6, 2017: Early Human Development
https://www.readbyqxmd.com/read/28183001/social-impairments-among-children-perinatally-exposed-to-oxytocin-or-oxytocin-receptor-antagonist
#11
Edwa Friedlander, Ohad Feldstein, David Mankuta, Maya Yaari, Ayelet Harel-Gadassi, Richard P Ebstein, Nurit Yirmiya
No abstract text is available yet for this article.
February 6, 2017: Early Human Development
https://www.readbyqxmd.com/read/28178582/short-term-weight-gain-velocity-in-infants-with-congenital-diaphragmatic-hernia-cdh
#12
Jason Gien, Karna Murthy, Eugenia K Pallotto, Beverly Brozanski, Louis Chicoine, Isabella Zaniletti, Ruth Seabrook, Sarah Keene, Deepthi Alapati, Nicolas Porta, Natalie Rintoul, Theresa R Grover
BACKGROUND: Appropriate post-natal growth remains a mainstay of therapeutic goals for infants with CDH, with the hypothesis that optimizing linear growth will improve survival through functional improvements in pulmonary hypoplasia. However, descriptions of growth and the effect on survival are limited in affected infants. OBJECTIVE: Describe in-hospital weight gain related to survival among infants with CDH. DESIGN/METHODS: Children's Hospitals Neonatal Database (CHND) identified infants with CDH born ≥34weeks' gestation (2010-14)...
February 5, 2017: Early Human Development
https://www.readbyqxmd.com/read/28171806/bedside-rop-screening-and-telemedicine-interpretation-integrated-to-a-neonatal-transport-system-economic-aspects-and-return-on-investment-analysis
#13
Gábor Kovács, Zsolt Somogyvári, Erika Maka, László Nagyjánosi
BACKGROUND AND AIM: Peter Cerny Ambulance Service - Premature Eye Rescue Program (PCA-PERP) uses digital retinal imaging (DRI) with remote interpretation in bedside ROP screening, which has advantages over binocular indirect ophthalmoscopy (BIO) in screening of premature newborns. We aimed to demonstrate that PCA-PERP provides good value for the money and to model the cost ramifications of a similar newly launched system. METHODS: As DRI was demonstrated to have high diagnostic performance, only the costs of bedside DRI-based screening were compared to those of traditional transport and BIO-based screening (cost-minimization analysis)...
February 4, 2017: Early Human Development
https://www.readbyqxmd.com/read/28131458/biomarkers-for-the-diagnosis-of-neonatal-sepsis-and-necrotizing-entercolitis-clinical-practice-guidelines
#14
Margaret Gilfillan, Vineet Bhandari
Sepsis and necrotizing enterocolitis are major contributors to morbidity and mortality in neonates, especially in those born preterm. While therapeutic interventions are available for both (for e.g. antibiotics), a major dilemma is early diagnosis so that these interventions can be done in a timely manner. As clinical evaluation alone is unreliable in identifying infants in the early stages of neonatal sepsis or necrotizing enterocolitis, there is a need to find specific biomarkers associated with these conditions to improve diagnostic capabilities...
January 25, 2017: Early Human Development
https://www.readbyqxmd.com/read/28107673/mri-patterns-of-brain-injury-and-neurodevelopmental-outcomes-in-neonates-with-severe-anaemia-at-birth
#15
Begoña Loureiro, Miriam Martinez-Biarge, Francesca Foti, Maria Papadaki, Frances M Cowan, Courtney J Wusthoff
AIMS: To define patterns of brain injury and associated neurodevelopmental outcomes in infants with severe neonatal anaemia. METHODS: We studied 20 infants with severe anaemia at birth (haemoglobin<7g/dL). Clinical details were analysed for causes of anaemia and co-morbidities. All had early brain magnetic resonance imaging (MRI) scans, which were reviewed for injury pattern. Neurodevelopmental outcomes were assessed at a median age of 24months. RESULTS: The aetiology of the anaemia was feto-maternal haemorrhage in 17 and antepartum haemorrhage in 3 infants...
January 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28095344/concordance-between-maternal-recall-of-birth-complications-and-data-from-obstetrical-records
#16
Kate Keenan, Alison Hipwell, Rose McAloon, Amy Hoffmann, Arpita Mohanty, Kelsey Magee
BACKGROUND: Prenatal complications are associated with poor outcomes in the offspring. Access to medical records is limited in the United States and investigators often rely on maternal report of prenatal complications. STUDY DESIGN AND AIMS: We tested concordance between maternal recall and birth records in a community-based sample of mothers participating in a longitudinal study in order to determine the accuracy of maternal recall of perinatal complications. SUBJECTS: Participants were 151 biological mothers, who were interviewed about gestational age at birth, birthweight, and the most commonly occurring birth complications: nuchal cord and meconium aspiration when the female child was on average 6years old, and for whom birth records were obtained...
January 14, 2017: Early Human Development
https://www.readbyqxmd.com/read/28094060/corrigendum-to-parenting-very-preterm-infants-and-stress-in-neonatal-intensive-care-units-early-hum-dev-101-2016-3-9
#17
Inês Baía, Mariana Amorim, Susana Silva, Michelle Kelly-Irving, Cláudia de Freitas, Elisabete Alves
No abstract text is available yet for this article.
January 13, 2017: Early Human Development
https://www.readbyqxmd.com/read/28089174/neonatal-acute-kidney-injury-severity-and-recovery-prediction-and-the-role-of-serum-and-urinary-biomarkers
#18
Deirdre U Sweetman
Neonatal acute kidney injury is common, in part due to incomplete renal maturation and also due to frequent exposure to risk factors for acute kidney injury such as perinatal asphyxia, extracorporeal-membrane-oxygenation, cardiac surgery, sepsis, prematurity and nephrotoxicity. However the current method by which acute kidney injury is diagnosed is sub-optimal and not universally accepted which impairs the accurate estimation of the true incidence of neonatal acute kidney injury. Serum Cystatin-C, urinary NGAL, KIM-1 and IL-18 are promising neonatal acute kidney injury biomarkers however the diagnosis of acute kidney injury remains serum creatinine/urine output-based in many studies...
January 11, 2017: Early Human Development
https://www.readbyqxmd.com/read/28088062/a-retrospective-audit-of-bacterial-culture-results-of-donated-human-milk-in-perth-western-australia
#19
Yahya Almutawif, Benjamin Hartmann, Megan Lloyd, Wendy Erber, Donna Geddes
INTRODUCTION: The bacterial content of donated human milk is either endogenous or introduced via contamination. Defining milk bank bacterial content will allow researchers to devise appropriate tests for significant and commonly encountered organisms. OBJECTIVE: A retrospective audit was conducted on data recorded from the Perron Rotary Express Milk Bank, King Edward Memorial Hospital, Subiaco, Western Australia. This aimed to describe the incidence of bacterial species detected in donated human milk and to identify potentially pathogenic bacteria...
January 11, 2017: Early Human Development
https://www.readbyqxmd.com/read/28057383/reference-values-for-nucleated-red-blood-cells-and-serum-lactate-in-very-and-extremely-low-birth-weight-infants-in-the-first-week-of-life
#20
Martin Poryo, Antonia Wissing, Aylin Aygün, Jürgen Geisel, Stefan Wagenpfeil, Michael Zemlin, Sascha Meyer
STUDY PURPOSE: To provide reference values for nucleated red blood cells and serum lactate concentrations in very and extremely low birth weight (VLBW/ELBW) infants in the first week of life. PATIENTS AND METHODS: Retrospective data analysis of serial, daily measurements of NRBC counts and serum lactate during the first 6days of life in VLBW and ELBW infants. RESULTS: In total, 250 infants<1500g were included in this study. Intrauterine growth retardation (IUGR) was seen in 87 (34...
January 2, 2017: Early Human Development
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