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Auris, Nasus, Larynx

Malene Hentze, Sten Schytte, Hans Pilegaard, Tejs Ehlers Klug
OBJECTIVE: Management of tracheal stenosis remains controversial. Endoscopic interventions commonly provide immediate relief of symptoms, but are associated with high recurrence rates. In contrast, high success rates have been reported in patients undergoing tracheal resection. However, well-defined indications and contraindications for tracheal resection are lacking and previous studies commonly ignore patient-related outcomes (e.g. dyspnoea). We aimed to evaluate the outcome of tracheal resection at our institution and identify risk factors for complications...
June 19, 2018: Auris, Nasus, Larynx
Su Young Jung, Hyung-Sik Kim, Jin-Young Min, Kyoung Jin Hwang, Sung Wan Kim
OBJECTIVE: Sleep hygiene-related conditions are factors that affect the symptoms experienced by patients with obstructive sleep apnea (OSA). However, very few studies have investigated the association between sleep hygiene and sleep symptoms, especially in patients with mild or moderate OSA. This study evaluated the relationship between factors related to sleep hygiene and clinical symptoms in patients with mild to moderate OSA. METHODS: One hundred and seventy-four patients who visited the Sleep Breathing Disorder Center at a tertiary academic center to evaluate suspected OSA were included...
June 19, 2018: Auris, Nasus, Larynx
Jeong-Whun Kim, Seung Hoon Lee, Hong Joong Kim, Chae-Seo Rhee, Seung-No Hong
OBJECTIVE: Our aim was to radiographically and histologically characterize the tongue base tissues removed after robotic surgery and to analyze their relationship with polysomnographic measurements in obstructive sleep apnea. METHODS: Medical records, radiographs and histologic specimen of the patients who underwent transoral robotic tongue base reduction surgery were retrospectively reviewed. Findings in computed tomography (CT) images, histopathological features of the removed tongue base tissues, and respiratory parameters in polysomnography were compared and analyzed...
June 18, 2018: Auris, Nasus, Larynx
Jung Ju Han, Jung Mee Park, Dong Kee Kim, So Young Park, Shi Nae Park
OBJECTIVE: This pilot study was performed to investigate the therapeutic effect of Valsalva maneuver on otitis media in adults and to evaluate the prognostic factors for the good response. METHODS: Thirty nine ears of 32 adult patients who were diagnosed as otitis media with effusion and managed by one-week Valsalva maneuver (>20/day) without any other medication were included in this study. Its therapeutic efficacy was evaluated and the prognostic factors which predict the response of Valsalva maneuver were analyzed by comparing various clinical and audiological factors between success and failure groups...
June 15, 2018: Auris, Nasus, Larynx
Isao Suzaki, Yurika Kimura, Akihiko Tanaka, Kojiro Hirano, Atsushi Ishibashi, Tomomi Mizuyoshi, Izumi Ando, Tatsuya Kitajima, So Watanabe, Yasuyuki Hinonira, Hitome Kobayashi
Eosinophilic otitis media (EOM), which is characterized by the accumulation of eosinophils in middle ear effusion and the middle ear mucosa, is a refractory type of otitis media that is often associated with asthma. Although an early diagnosis and appropriate treatment are necessary to prevent the progression of hearing loss in patients with EOM, there are currently no well-established treatments for this condition. We treated a 60-year-old male patient with asthma and EOM. The patient's asthma was poorly controlled, despite the use of high-dose inhaled corticosteroids, long-acting beta-agonist treatment, and the regular use of systemic corticosteroids...
June 13, 2018: Auris, Nasus, Larynx
Yukiyoshi Hyo, Hisaki Fukushima, Tamotsu Harada, Hirotaka Hara
Although nasal septal abscess (NSA) was formerly common, it has become rare since the development of antibiotics. NSA, if left untreated, can lead to intracranial complications such as meningitis and eventually result in saddle-nose deformity. NSA often occurs after injury, and indigenous skin bacteria such as Staphylococcus aureus are frequently detected. We treated a patient who had injured the upper alveolus in a fall on the stairs and developed NSA two weeks later. Anaerobic bacteria, including Veillonella parvula and Peptostreptococcus sp...
June 7, 2018: Auris, Nasus, Larynx
So Young Kim, Jae Joon Han, Seung Ha Oh, Jun Ho Lee, Myung-Whan Suh, Me Hee Kim, Moo Kyun Park
OBJECTIVE: This study was aimed to investigate whether wideband tympanometry (WBT) can distinguish among various kinds of conductive hearing loss and provide additional information. METHODS: We recruited normal subjects and patients with conductive hearing loss due to the following reasons: tympanic membrane perforation only, ossicular chain problem only, and one or other of those conditions combined with mastoid problems. Wideband absorbance at ambient pressure, peak pressure, resonance frequency, and averaged tympanogram data were measured by WBT and compared between the normal, tympanic membrane perforation only, ossicular chain problem only, and combined with mastoid problems groups...
June 6, 2018: Auris, Nasus, Larynx
Masahiro Okada, Koichiro Suemori, Daiki Takagi, Masato Teraoka, Hiroyuki Yamada, Jun Ishizaki, Takuya Matsumoto, Hitoshi Hasegawa, Naohito Hato
OBJECTIVE: To investigate treatment outcomes, hearing outcomes, and adverse effects of rituximab (RTX) for intractable otitis media with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV). METHODS: Twenty-three patients who met the criteria proposed by the OMAAV study group were included. RTX was used for patients who had difficulty achieving induction of remission using glucocorticoids (GC) and intravenous cyclophosphamide (IVCY). RESULTS: Six patients were treated with RTX (RTX group), while 17 patients did not require RTX for induction of remission (non-RTX group)...
June 6, 2018: Auris, Nasus, Larynx
Hafizah Husna Johari, Irfan Mohamad, Ida Sadja'ah Sachlin, Mohd Ezane Aziz, Teoh Yuen Mey, Ramiza Ramza Ramli
OBJECTIVE: This study was done to determine frontal recess anatomy cell variations and its association with frontal sinusitis. The incidence of frontal recess cells in the population, the presence of frontal recess cell variations in chronic rhinosinusitis and non-chronic rhinosinusitis and the association of frontal recess cell variation in the development of frontal sinusitis were also assessed. METHODS: This was an observational, retrospective cross-sectional study of computed tomography (CT) scan of paranasal sinus that had been performed on patients in Hospital Universiti Sains Malaysia and Hospital Sultanah Bahiyah done from January 2009 until December 2016...
June 4, 2018: Auris, Nasus, Larynx
David Bächinger, Daiki Takagi, Hiroyuki Yamada, Masato Teraoka, Masahiro Okada, Jun Hyodo, Christof Röösli, Alexander M Huber, Naohito Hato
OBJECTIVE: In the assessment of chronic otitis media (COM) and its treatment, patient-reported outcomes are becoming increasingly important. The aim of the present study was to translate and validate the Zurich chronic middle ear inventory (ZCMEI-21) in Japanese in order to provide the first Japanese-language instrument for measuring health-related quality of life (HRQoL) in COM. METHODS: The ZCMEI-21 was translated into Japanese according to published guidelines...
June 2, 2018: Auris, Nasus, Larynx
Kyurin Hwang, Bo Gyung Kim, Jong Dae Lee, Eek-Sung Lee, Tae Kyeong Lee, Ki-Bum Sung
OBJECTIVES: We questioned whether the extent of vestibular impairment affected the recovery of vestibular function in acute vestibular neuritis (VN). The objective of this study was to identify how the extent of vestibular impairment influenced the recovery from canal paresis (CP) in patients with VN. METHODS: We retrospectively reviewed the medical records of 46 patients diagnosed with acute vestibulopathy between January 2012 and December 2015. Pure-tone audiometry, a caloric test, and cervical vestibular evoked myogenic potential (cVEMP) testing were performed in all patients...
June 1, 2018: Auris, Nasus, Larynx
Doh Young Lee, Karam Kang, Hwaejoon Jung, Young Min Park, Jae-Gu Cho, Seung-Kuk Baek, Soon-Young Kwon, Kwang-Yoon Jung, Jeong-Soo Woo
OBJECTIVE: In this study, we analyzed clinicopathological characteristics and survival outcomes according to extranodal involvement of diffuse large B-cell lymphoma (DLBCL) in the head and neck. METHODS: A retrospective analysis was conducted on 110 patients from 2004 to 2014 with CD20-positive DLBCL involving the head and neck area. Patients were categorized into two groups, extranodal and nodal, according to involvement of extranodal sites in the head and neck...
May 31, 2018: Auris, Nasus, Larynx
Xudong Chen, Litao Zhang, Shixiong Tang
OBJECTIVE: MicroRNAs (miRNAs) are aberrantly expressed in various tumors and play a critical role in the progression and development of tumors. However, there is little information about the role of miR-4497 in laryngeal squamous cell carcinoma (LSCC). The aim of this study is to investigate the role of miR-4497 in LSCC. METHODS: MiR-4497 expression in tumor tissues and adjacent normal tissues was measured by RT-PCR. The effects of miR-4497 on cell viability and apoptosis were evaluated by the MTT assay, Flow cytometry and caspase-3 activity assay...
May 26, 2018: Auris, Nasus, Larynx
Takeshi Watanabe, Haruo Yoshida, Kan Kishibe, Yuka Morita, Naohiro Yoshida, Haruo Takahashi, Yasuaki Harabuchi
OBJECTIVE: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) without systemic symptoms but with initial symptoms related to the ear, such as hearing loss, otalgia, and dizziness, has recently been reported. We have categorized this condition as otitis media with AAV (OMAAV), and have recently proposed its diagnostic criteria. METHODS: To determine the effectiveness of cochlear implantation (CI) in patients with profound hearing loss due to OMAAV...
May 25, 2018: Auris, Nasus, Larynx
Mika Adachi, Mitsuhiro Sato, Mariko Miyazaki, Osamu Hotta, Koji Hozawa, Toshinobu Sato, Yoshio Taguma, Yukio Katori
OBJECTIVE: Tonsillectomy combined with steroid-pulse therapy is a widely accepted method for the treatment of IgA nephropathy (IgAN) in Japan. However, the indication of tonsillectomy for IgAN is still controversial, and the timing of tonsillectomy is not clearly defined for the protocol of this therapy. Based on the results of a randomized control trial in Japan, the Evidence-Based Clinical Practice Guidelines for IgA nephropathy 2014 (edited in Japan) recommended tonsillectomy combined with steroid-pulse therapy for Grade C1...
May 19, 2018: Auris, Nasus, Larynx
Yusuke Kikuoka, Ryo Kawata, Masaaki Higashino, Tetsuya Terada, Shin-Ichi Haginomori
OBJECTIVE: The marginal mandibular branch of the facial nerve must be protected during surgery for benign diseases of submandibular gland. Methods for protecting the marginal mandibular branch include the nerve identification method and the non-identification method. METHODS: We performed submandibular gland surgery in 138 patients with benign submandibular gland diseases using the non-identification method to preserve the marginal mandibular branch. In brief, the submandibular gland capsule is incised at the inferior border of the gland and detached along the gland parenchyma...
May 19, 2018: Auris, Nasus, Larynx
Takafumi Nakada, Masaaki Teranishi, Yukio Ueda, Michihiko Sone
OBJECTIVE: Patients with benign paroxysmal positional vertigo (BPPV) can have vitamin D deficiency, which is a cause of abnormal bone turnover. Several studies have established a relationship between osteoporosis and BPPV. The World Health Organization Fracture Risk Assessment Tool, widely known as FRAX® (, is a computer-based algorithm for assessing fracture risk. No direct comparison has been made between the FRAX scores of patients with BPPV and controls...
May 18, 2018: Auris, Nasus, Larynx
Hideaki Goto, Naomi Kiyota, Naoki Otsuki, Yoshinori Imamura, Naoko Chayahara, Hirotaka Suto, Yoshiaki Nagatani, Masanori Toyoda, Toru Mukohara, Ken-Ichi Nibu, Toshihiko Kasahara, Yasuhiro Ito, Akihiro Miya, Mitsuyoshi Hirokawa, Akira Miyauchi, Hironobu Minami
Sorafenib and lenvatinib showed efficacy for patients with radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC) in pivotal phase 3 clinical trials. Although the efficacy of lenvatinib in patients who received previous treatment with multi-target kinase inhibitors (m-TKIs), including sorafenib, was reported, the efficacy of sorafenib in patients who previously received lenvatinib remains unknown. A 75-year-old woman diagnosed as RAI-refractory poorly differentiated carcinoma with multiple lung metastases and started treatment with lenvatinib...
May 17, 2018: Auris, Nasus, Larynx
Sabri Özden, Servet Güreşci, Barış Saylam, Gül Dağlar
OBJECTIVE: The main cause of primary hyperparathyroidism is a single parathyroid adenoma. Parathyroid lipoadenomas contain abundance of fat cells. Because of these histological features, they can mimic normal parathyroid tissue at the histopathologic examination and radiological imaging could be difficult to localize lipoadenomas. CLINICAL PRESENTATION: In this case report, we present three cases of functional parathyroid lipoadenomas. CONCLUSION: Preoperative imaging modalities often can't localize lipoadenoma...
May 16, 2018: Auris, Nasus, Larynx
Chisato Mogi, Hirotaka Shinomiya, Natsumi Fujii, Tomoyuki Tsuruta, Naruhiko Morita, Tatsuya Furukawa, Masanori Teshima, Maki Kanzawa, Mitsuyoshi Hirokawa, Naoki Otsuki, Ken-Ichi Nibu
Carcinoma arising in lingual thyroid is an extremely rare entity accounting for only 1% of all reported ectopic thyroids. Here, we report a case of carcinoma arising in lingual thyroid, which has been successfully managed by transoral resection and bilateral neck dissections. A lingual mass 4-cm in diameter with calcification was incidentally detected by computed tomography at medical check-up. No thyroid tissue was observed in normal position. Ultrasound examination showed bilateral multiple lymphadenopathies...
May 15, 2018: Auris, Nasus, Larynx
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