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Auris, Nasus, Larynx

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https://www.readbyqxmd.com/read/28648812/neck-metastasis-in-patients-with-t1-2-supraglottic-cancer
#1
Tomoyasu Tachibana, Yorihisa Orita, Hidenori Marunaka, Sei-Ichiro Makihara, Misato Hirai, Yuka Gion, Kana Ikegami, Kentaro Miki, Takuma Makino, Yasuyuki Noyama, Yasutoshi Komatsubara, Miyuki Kimura, Tadashi Yoshino, Kazunori Nishizaki, Yasuharu Sato
OBJECTIVES: Unlike glottic cancer, supraglottic cancer often presents with neck metastases. This different might be attributable to the location of the primary lesion. This study aimed to clarify the relationships between the sublocation of T1-2 supraglottic cancer, human papillomavirus (HPV) infection, neck metastasis, and prognosis of supraglottic cancer. METHODS: This retrospective clinical study investigated 55 Japanese patients with T1-2 supraglottic cancer treated between 1994 and 2015...
June 22, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28648811/a-case-of-improved-hearing-with-cochlear-implantation-in-gaucher-disease-type-1
#2
Shiori Endo, Kunihiro Mizuta, Takashi Yamatodani, Hiroshi Nakanishi, Kumiko Hosokawa, Kiyoshi Misawa, Seiji Hosokawa, Hiroyuki Mineta
Gaucher disease is a lysosomal storage disorder that is caused by congenital defective function of the enzyme glucocerebrosidase. Glucocerebroside that is not hydrolyzed by glucocerebrosidase mainly accumulates in the reticular tissue. We describe a Japanese boy with Gaucher disease type 1 who developed bilateral profound sensorineural hearing loss within approximately 4years. We performed cochlear implantation initially on his right ear and again on his left ear 5 months later. The cochlear implants were successfully utilized with a speech discrimination score of 95% on a Japanese sentence recognition test...
June 22, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28647143/a-tertiary-center-experience-with-velopharyngeal-surgical-techniques-for-treatment-of-snoring-and-obstructive-sleep-apnea
#3
Omer Karakoc, Murat Binar, Umit Aydin, Hakan Genc, Timur Akcam, Mustafa Gerek
OBJECTIVES: The aim of this study was to assess the outcomes of patients who treated with the relatively new surgical procedures; anterior palatoplasty (AP), Cahali lateral pharyngoplasty (CLP), and expansion sphincter pharyngoplasty (ESP) for habitual snoring or obstructive sleep apnea (OSA). METHODS: Prospective series of 93 patients were evaluated. The performed surgical techniques, polysomnographic outcomes, pre- and postoperative clinical parameters, and complication rates were assessed...
June 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28641905/high-gpx1-expression-predicts-poor-survival-in-laryngeal-squamous-cell-carcinoma
#4
REVIEW
Qicheng Zhang, Hongli Xu, Yiwen You, Jie Zhang, Renjie Chen
OBJECTIVE: Several studies have demonstrated that abnormal glutathione peroxidases 1 (Gpx1) expression can influence the biological behavior of malignant cells. However, the roles of Gpx1 in laryngeal squamous cell carcinoma (LSCC) remain unknown. The purpose of this study is to analyze the Gpx1 expression and prognostic significance in LSCC patients. METHODS: Gpx1 mRNA levels in laryngeal tissues were determined by qRT-PCR. Meanwhile, We examined the expression levels of Gpx1 protein in 140 primary tumor tissues and 28 cases of normal tissues by immunohistochemistry (IHC) analysis on tissue microarrays (TMA)...
June 19, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28633976/transnasal-endoscopic-removal-of-bilateral-postoperative-maxillary-cysts-after-aesthetic-orthognathic-ssurgery-differences-from-that-of-caldwell-luc-operations
#5
Hyung Chae Yang, Sung Hoon Kang, Sung Ho Yoon, Hyong-Ho Cho
Postoperative maxillary cysts (PMCs) after orthognathic surgery are a rare disease condition. In this study, we reported first case of bilateral PMCs after cosmetic orthognathic surgery which was treated via the intranasal endoscopic approach. In addition, we compared the characteristics of PMCs after aesthetic orthognathic surgery with those of PMCs after Caldwell-Luc operation. We expect that this case will be helpful to surgeons who encounter similar cases.
June 17, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28625531/the-extended-bundle-of-the-tensor-veli-palatini-anatomic-consideration-of-the-dilating-mechanism-of-the-eustachian-tube
#6
Ryuhei Okada, Satoru Muro, Kohtaro Eguchi, Kohei Yagi, Hisayo Nasu, Kumiko Yamaguchi, Koh Miwa, Keiichi Akita
OBJECTIVE: The aim of this study was to analyze the topographical structures of the muscles surrounding the Eustachian tube. MATERIALS AND METHODS: We conducted macroscopic and histological studies of 24 halves of 12 heads from Japanese cadavers. RESULTS: The main findings were as follows: 1) the infero-lateral muscle bundles of the tensor veli palatini didn't turn medially at the pterygoid hamulus but were distributed laterally and continuous with the buccinator; 2) the tensor veli palatini attached laterally to the membranous part of the Eustachian tube; 3) the superior pharyngeal constrictor was not only adjacent to the buccinator at the pterygomandibular raphe but also had muscular continuation with it laterally and 4) some bundles of the superior pharyngeal constrictor adhered with the palatine aponeurosis...
June 15, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28624429/squamous-cell-carcinoma-of-the-retromolar-trigone-treatment-outcomes
#7
Hideaki Nishi, Takeshi Shinozaki, Toshifumi Tomioka, Takashi Maruo, Ryuichi Hayashi
OBJECTIVE: Squamous cell carcinoma (SCC) of the retromolar trigone is uncommon, accounting for 1.4% of all oral cancer cases in Japan. Few studies have examined the optimal treatment for this cancer. The aim of this study was to evaluate the outcome of treatment for primary SCC of the retromolar area. METHODS: We retrospectively analyzed the outcome and prognosis of 45 patients (38 men, 7 women) with SCC of the retromolar trigone who underwent treatment in our department between July 1992 and March 2011...
June 14, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28624428/undifferentiated-sarcoma-of-the-sphenoid-sinus
#8
Masaya Nagaishi, Kensuke Suzuki, Yoshiki Sugiura, Issei Takano, Yoshihiro Tanaka, Akio Hyodo
Paranasal sinuses sarcomas are rare and no treatments have been established. We report a young-adult case of sphenoid sinus sarcoma treated by carbon-ion radiotherapy. The patient presented with progressive left-sided visual impairment. A tumor was then identified and partial resection by transnasal approach was performed. The resected mass showed typical morphology of mesenchymal tumor, and morphological and molecular analyses ruled out a predominant-differentiation phenotype. The pathological diagnosis was undifferentiated sarcoma...
June 14, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28624427/a-case-grafted-with-polyglycolic-acid-sheets-and-fibrin-glue-for-protection-after-temporary-resection-of-a-metastatic-cervical-skin-tumor
#9
Takashi Matsuzuka, Masahiro Suzuki, Masakazu Ikeda, Kaoru Sato, Junko Fujimoto, Rumi Hosaka, Yuko Tanji, Shu Soeda, Shigeyuki Murono
The aim of this case report was to evaluate the usefulness of a grafting with polyglycolic acid sheet and a fibrin glue spray (PGA sheet grafting) after resection of a cervical skin tumor. A 61-year-old woman presented with left cervical skin tumor resistance to chemo-radiotherapy. She had been undergoing multimodal therapy for ovarian serous papillary adenocarcinoma for the previous six years. Although she had a poor general condition and a cervical skin tumor of 9cm in diameter, which was painful and easy bleeding, had offensive smell, she hoped to return to her job...
June 14, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28602229/diagnosis-and-following-up-of-m%C3%A3-ni%C3%A3-re-s-disease-using-multifrequency-tympanometry-cutoff-values-and-temporal-changes-in-measurements
#10
Kazuyuki Ishizu, Akihiro Tamae, Kazuhiko Kubo, Takamasa Yoshida, Nozomu Matsumoto, Tetsurou Yasui, Takashi Nakagawa
OBJECTIVE: This study aimed to verify cutoff values for G width (the width of bimodal peaks for the waveform obtained when measuring conductance at 2000Hz) in Japanese individuals diagnosed with Ménière's disease (MD) using multifrequency tympanometry (MFT) and to determine the relationship between the G width and ability to hear low-pitched sounds using measurements over time. METHODS: The study included 51 patients with clinically diagnosed MD, who had not undergone endolymphatic sac surgery, but had no other known ear disease (57 ears in patients aged 22-80 years were affected, and 45 ears in patients aged 18-83 years were unaffected; mean age: 53...
June 8, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28595773/endoscopic-endonasal-management-of-esthesioneuroblastoma-a-retrospective-multicenter-study
#11
Takayuki Nakagawa, Satoru Kodama, Masayoshi Kobayashi, Tetsuji Sanuki, Shuho Tanaka, Nobuhiro Hanai, Toyoyuki Hanazawa, Hiroko Monobe, Hidenori Yokoi, Motohiko Suzuki, Masaru Yamashita, Koichi Omori
OBJECTIVE: The aim of the present study was to illustrate the safety and utility of the endoscopic endonasal approach (EEA) for the treatment of esthesioneuroblastomas (ENB). METHODS: We retrospectively reviewed patients with a diagnosis of ENB between March 2008 and February 2016 at 10 tertiary referral hospitals in Japan, and assessed demographic data, stage of disease, surgical approach, outcomes and postoperative complications. RESULTS: A total of 22 patients (10 males and 12 females; mean age at presentation, 49...
June 5, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28579442/phosphaturic-mesenchymal-tumor-of-the-nasal-cavity-and-paranasal-sinuses-a-clinical-curiosity-presenting-a-diagnostic-challenge
#12
Shubhada V Kane, Aanchal Kakkar, Nikita Oza, Epari Sridhar, Prathamesh S Pai
Phosphaturic mesenchymal tumor (PMT) is a rare mesenchymal neoplasm associated with tumor-induced osteomalacia (TIO) and elevated serum FGF-23. Common in extremities, PMT rarely occurs in sinonasal region. We report a series of sinonasal PMT diagnosed at our institute over a 6-year period. Six cases of sinonasal PMT were identified during this period, of which five presented with features of TIO. Median age of patients was 45.5 years. All six tumors were composed of stellate to spindled cells, with prominent staghorn vasculature in four cases...
June 1, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28552275/delayed-type-of-allergic-skin-reaction-to-candida-albicans-in-eosinophilic-rhinosinusitis-cases
#13
Nozomu Wakayama, Shoji Matsune, Kimihiro Okubo
OBJECTIVE: Eosinophilic chronic rhinosinusitis (ECRS) is frequently complicated by asthma, and recognized as refractory and persistent rhinosinusitis. However, the detailed pathophysiology of ECRS has not been elucidated yet. In this study, we investigated the association between recurrent ECRS and intradermal testing to multi-antigens including Candida albicans. METHODS: The subjects were 49 cases of bilateral chronic rhinosinusitis including 24 ECRS cases. They underwent endoscopic sinus surgery and submitted to pathological examination...
May 25, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28552274/effectiveness-of-hemostatic-gelatin-sponge-as-a-packing-material-after-septoplasty-a-prospective-randomized-multicenter-study
#14
Sung-Dong Kim, Sung-Lyong Hong, Min-Jung Kim, Joo-Yeon Kim, Yong-Wan Kim, Soo-Kweon Koo, Kyu-Sup Cho
OBJECTIVE: Although hemostatic gelatin sponge is a gelatin-based packing material with a powerful hemostatic effect, there were no studies in regard to its efficacy for packing material after septoplasty. The purpose of this study was to investigate the efficacy of hemostatic gelatin sponge nasal packing on patient's subjective symptoms, hemostasis, and wound healing following septoplasty. SUBJECTS AND METHODS: Seventy six adult patients with nasal septum deviation requiring septoplasty were included...
May 25, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28546036/relationship-between-various-anthropometric-measures-and-apnea-hypopnea-index-in-korean-men
#15
Jeong-Hong Kim, Yong Cheol Koo, Hyung Ju Cho, Ju Wan Kang
OBJECTIVE: Body mass index (BMI) has been shown to be strongly correlated with severity of OSA. However, BMI has not been shown to be correlated with sleep apnea in all patients studied. The purpose of this study was to evaluate the relationship between various anthropometric measures and severity of OSA according to BMI in men. METHODS: We conducted a retrospective analysis of the medical records of patients who visited for evaluation of OSA. Polysomnography results, height, weight, neck circumference, waist circumference, and hip circumference were obtained in all subjects...
May 22, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28522300/primary-reconstructive-method-for-tracheal-defect-from-invasion-by-differentiated-thyroid-carcinoma
#16
Atsumori Hamahata, Takeshi Beppu, Takashi Yamaki, Hiroyuki Sakurai
Differentiated thyroid carcinoma is not highly malignant, and thus surgical resection is the most common treatment even if the carcinoma has invaded the trachea. Although some cases exist in which the carcinoma invades the trachea, using the tracheal window resection method allows complete resection of the carcinoma. Yet these patients must often control a large tracheocutaneous wound until reconstructive surgery is performed because such surgery occurs secondarily. Our hospital admitted three patients for which tracheally invasive, differentiated thyroid carcinoma was surgically resected...
May 15, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28511890/intratympanic-steroid-delivery-by-an-indwelling-catheter-in-refractory-severe-sudden-sensorineural-hearing-loss
#17
Diego Zanetti, Federica Di Berardino, Nader Nassif, Luca Oscar Redaelli De Zinis
OBJECTIVE: Many studies over the last decade showed favorable outcomes with intratympanic (IT) steroid treatment, alone as salvage treatment or in combination with conventional systemic therapy (ST). However, in severe to profound sensorineural hearing loss resistant to ST, the optimal infusion mode, the type and concentration of the solution, the preferable drug, its total amount, and the duration and fractionation of the treatment are still debated. Aim of the study was to investigate the feasibility and the outcomes of a direct and constant IT delivery of dexamethasone (DEX) by means of a new indwelling catheter...
May 13, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28511889/severely-infected-pneumoceles-of-the-frontal-sinus-in-patients-with-mental-retardation-and-brain-atrophy-treated-by-endoscopic-sinus-surgery
#18
Ichiro Tojima, Hirotaka Kikuoka, Takao Ogawa, Takeshi Shimizu
We herein present three cases of abnormally expanded frontal sinuses (pneumoceles) with severe infection in patients with mental retardation and brain atrophy. Two patients previously underwent laryngotracheal separation surgery, and bacteriological examinations of purulent nasal discharge revealed infections caused by drug-resistant bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. As conservative medical treatments were ineffective, all three patients were treated by computed tomography-guided endoscopic sinus surgery...
May 13, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28506522/thick-tumor-capsule-is-a-valuable-risk-factor-for-distant-metastasis-in-follicular-thyroid-carcinoma
#19
Wataru Shimbashi, Iwao Sugitani, Kazuyoshi Kawabata, Hiroki Mitani, Kazuhisa Toda, Keiko Yamada, Yukiko Sato
OBJECTIVE: While the biological behavior of follicular thyroid carcinoma (FTC) has been studied in great detail using clinical experience, few studies have investigated pre- or intraoperative factors related to the risk of distant metastasis (DM) among patients with FTC. The aim of this study was to analyze the characteristics of FTC with DM. METHODS: This study retrospectively investigated 102 patients with FTC who underwent surgery between 1988 and 2013. We compared clinicopathological characteristics between FTC with and without DM...
May 12, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28502583/homozygous-ednrb-mutation-in-a-patient-with-waardenburg-syndrome-type-1
#20
Noriko Morimoto, Hideki Mutai, Kazunori Namba, Hiroki Kaneko, Rika Kosaki, Tatsuo Matsunaga
OBJECTIVE: To examine and expand the genetic spectrum of Waardenburg syndrome type 1 (WS1). METHODS: Clinical features related to Waardenburg syndrome (WS) were examined in a five-year old patient. Mutation analysis of genes related to WS was performed in the proband and her parents. Molecular modeling of EDNRB and the p.R319W mutant was conducted to predict the pathogenicity of the mutation. RESULTS: The proband showed sensorineural hearing loss, heterochromia iridis, and dystopia canthorum, fulfilling the clinical criteria of WS1...
May 11, 2017: Auris, Nasus, Larynx
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