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Sexually Transmitted Diseases

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https://www.readbyqxmd.com/read/27898577/decline-in-herpes-simplex-virus-type-2-among-non-injecting-heroin-and-cocaine-users-in-new-york-city-2005-to-2014-prospects-for-avoiding-a-resurgence-of-human-immunodeficiency-virus
#1
Don C Des Jarlais, Kamyar Arasteh, Jonathan Feelemyer, Courtney McKnight, Susan Tross, David C Perlman, Aimee N C Campbell, Holly Hagan, Hannah L F Cooper
BACKGROUND: Herpes simplex virus type 2 (HSV-2) infection increases both susceptibility to and transmissibility of human immunodeficiency virus (HIV), and HSV-2 and HIV are often strongly associated in HIV epidemics. We assessed trends in HSV-2 prevalence among non-injecting drug users (NIDUs) when HIV prevalence declined from 16% to 8% among NIDUs in New York City. METHODS: Subjects were current non-injecting users of heroin and/or cocaine and who had never injected illicit drugs...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898576/sexually-transmitted-disease-testing-and-uptake-of-human-papillomavirus-vaccine-in-a-large-online-survey-of-us-men-who-have-sex-with-men-at-risk-for-hiv-infection-2012
#2
Erin M Kahle, Elissa Meites, R Craig Sineath, Muazzam Nasrullah, Kristina E Bowles, Elizabeth DiNenno, Patrick S Sullivan, Travis Sanchez
National guidelines recommend annual human immunodeficiency virus (HIV)/sexually transmitted disease testing for sexually active men who have sex with men (MSM) and vaccination against human papillomavirus for MSM through age 26. A 2012 online survey of 2,794 MSM found that 51%, 36%, and 14% reported receiving human immunodeficiency virus testing, sexually transmitted disease testing, and human papillomavirus vaccination, respectively.
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898575/rate-of-decline-in-nontreponemal-antibody-titers-and-seroreversion-after-treatment-of-early-syphilis
#3
Arlene C Seña, Mark Wolff, Frieda Behets, David H Martin, Peter Leone, Carol Langley, Linda McNeil, Edward W Hook
BACKGROUND: Syphilis management is complex and demonstration of treatment response requires monitoring of nontreponemal antibody titers for a ≥ 4-fold decline and/or seroreversion to nonreactive titers. METHODS: We evaluated data from a multicenter clinical trial of syphilis treatment conducted from 2000 to 2009 involving human immunodeficiency virus (HIV)-negative patients 18 years or older with early syphilis. To assess the rate of titer decline and seroreversion after effective therapy, rapid plasma reagin (RPR) titers were analyzed at 1, 3, 6, 9, and 12 months among patients with an appropriate treatment response...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898574/factors-associated-with-primary-care-physician-knowledge-of-the-recommended-regimen-for-treating-gonorrhea
#4
Marta Bornstein, Faruque Ahmed, Roxanne Barrow, Jami Fraze Risley, Sheena Simmons, Kimberly A Workowski
BACKGROUND: The recommended regimen for treating uncomplicated gonorrhea has changed over time, due to the emergence of antimicrobial resistance. We assessed physician knowledge of the recommendation for treating uncomplicated urogenital gonorrhea in adolescents and adults using ceftriaxone and azithromycin dual therapy. METHODS: We analyzed DocStyles 2015 survey data from 1357 primary care physicians practicing for at least 3 years who provided screening, diagnosis, or treatment for sexually transmitted diseases to one or more patients in an average month...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898573/improving-physician-recommendations-for-human-papillomavirus-vaccination-the-role-of-professional-organizations
#5
Yulin Hswen, Melissa B Gilkey, Barbara K Rimer, Noel T Brewer
BACKGROUND: To address low human papillomavirus (HPV) vaccination coverage, the American Academy of Family Physicians (AAFP) and the American Academy of Pediatrics (AAP) have launched national campaigns encouraging physicians to deliver strong HPV vaccine recommendations. We surveyed family physicians and pediatricians to examine the impact of these efforts on physicians' recommendation practices. METHODS: A national sample of family physicians and pediatricians (n = 776) completed our online survey in 2014...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898572/sexually-transmitted-infections-and-associated-risk-factors-among-street-based-and-residence-based-female-sex-workers-in-dhaka-bangladesh
#6
Rasheda Khanam, Masud Reza, Dilruba Ahmed, Mustafizur Rahman, M Shah Alam, Salima Sultana, Anadil Alam, Sharful I Khan, Kenneth H Mayer, Tasnim Azim
BACKGROUND: Female sex workers (FSWs) in Bangladesh remain at elevated risk of sexually transmitted infections (STIs) although the human immunodeficiency virus (HIV) prevalence among them is low. Recent information on the burden and etiological diagnosis of STIs among them has been lacking. This study examines prevalence and risk behaviors of selected STIs among FSWs in Dhaka in 2014. METHODS: Between August and October 2014, a cross-sectional study was conducted among street-based and residence-based FSWs receiving HIV prevention services at 24 drop in centers in Dhaka...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898571/single-dose-compared-with-multidose-metronidazole-for-the-treatment-of-trichomoniasis-in-women-a-meta-analysis
#7
Katharine Howe, Patricia J Kissinger
BACKGROUND: Trichomonas vaginalis is the most common curable sexually transmitted infection worldwide. Although the Centers for Disease Control and Prevention and the World Health Organization recommend a single 2-g dose of metronidazole for the first line of treatment for T. vaginalis among human immunodeficiency virus (HIV) negative women, high rates of repeat infections are found. The purpose of this meta-analysis was to compare treatment failure between single versus multidose metronidazole for the treatment of T...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898570/are-centers-for-disease-control-and-prevention-guidelines-for-preexposure-prophylaxis-specific-enough-formulation-of-a-personalized-hiv-risk-score-for-pre-exposure-prophylaxis-initiation
#8
Matthew R Beymer, Robert E Weiss, Catherine A Sugar, Linda B Bourque, Gilbert C Gee, Donald E Morisky, Suzanne B Shu, Marjan Javanbakht, Robert K Bolan
BACKGROUND: Preexposure prophylaxis (PrEP) has emerged as a human immunodeficiency virus (HIV) prevention tool for populations at highest risk for HIV infection. Current US Centers for Disease Control and Prevention (CDC) guidelines for identifying PrEP candidates may not be specific enough to identify gay, bisexual, and other men who have sex with men (MSM) at the highest risk for HIV infection. We created an HIV risk score for HIV-negative MSM based on Syndemics Theory to develop a more targeted criterion for assessing PrEP candidacy...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898569/elimination-of-mother-to-child-transmission-of-syphilis-in-the-americas-a-goal-that-must-not-slip-away
#9
Lola V Stamm, Angel A Noda
No abstract text is available yet for this article.
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898568/whole-exome-sequencing-to-identify-novel-biological-pathways-associated-with-infertility-after-pelvic-inflammatory-disease
#10
Brandie D Taylor, Xiaojing Zheng, Toni Darville, Wujuan Zhong, Kranti Konganti, Olayinka Abiodun-Ojo, Roberta B Ness, Catherine M O'Connell, Catherine L Haggerty
BACKGROUND: Ideal management of sexually transmitted infections (STI) may require risk markers for pathology or vaccine development. Previously, we identified common genetic variants associated with chlamydial pelvic inflammatory disease (PID) and reduced fecundity. As this explains only a proportion of the long-term morbidity risk, we used whole-exome sequencing to identify biological pathways that may be associated with STI-related infertility. METHODS: We obtained stored DNA from 43 non-Hispanic black women with PID from the PID Evaluation and Clinical Health Study...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898567/utilization-of-the-cepheid-xpert%C3%A2-ct-ng-sample-adequacy-control-to-determine-the-influence-of-the-urethral-swab-on-cellular-content-in-post-swab-versus-pre-swab-urine
#11
Stephen J Jordan, Barbara Van Der Pol, Edward W Hook
Chlamydia trachomatis/Neisseria gonorrhoeae assay performance in males is typically determined using post-swab urine, though pre-swab urine is used in practice. We collected swabs and urine from men and used the Cepheid Xpert® CT/NG sample adequacy control to determine the effect of swab collection on urine cellular content. No difference was observed.
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898566/antiretroviral-therapy-initiation-is-not-associated-with-risky-sexual-behavior-among-heterosexual-human-immunodeficiency-virus-infected-persons-in-serodiscordant-partnerships
#12
Andrew Mujugira, Connie Celum, Kenneth Ngure, Katherine K Thomas, Elly Katabira, Jared M Baeten
BACKGROUND: Few prospective studies have assessed whether antiretroviral therapy (ART) use is associated with changes in sexual risk behavior of human immunodeficiency virus (HIV)-infected persons in known HIV-serodiscordant partnerships. METHODS: We conducted a longitudinal analysis of HIV-infected persons with known uninfected partners enrolled in the Partners Pre-Exposure Prophylaxis Study in Kenya and Uganda. Antiretroviral therapy use and self-reported sexual behavior were ascertained every 3 months...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27898565/quantitative-real-time-polymerase-chain-reaction-for-the-diagnosis-of-mycoplasma-genitalium-infection-in-south-african-men-with-and-without-symptoms-of-urethritis
#13
Marie Cecilia le Roux, Anwar Ahmed Hoosen
BACKGROUND: This study was done to diagnose Mycoplasma genitalium infection based on bacterial load in urine specimens from symptomatic and asymptomatic men. METHODS: Urine specimens from 94 men with visible urethral discharge, 206 with burning on micturition and 75 without symptoms presenting to a family practitioner were tested for M. genitalium as well as Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis by transcription-mediated amplification assays...
November 28, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27835630/treponema-pallidum-pallidum-genotypes-and-macrolide-resistance-status-in-syphilitic-lesions-among-patients-at-2-sexually-transmitted-infection-clinics-in-lima-peru-erratum
#14
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27835629/the-association-of-health-seeking-behaviors-with-human-papillomavirus-vaccination-status-among-high-risk-urban-youth
#15
Holly B Fontenot, Terrence Lee-St John, Ralph Vetters, Danielle Funk, Chris Grasso, Kenneth H Mayer
BACKGROUND: Vaccination is the primary strategy to reduce the burden of human papillomavirus (HPV) related diseases in the United States. Unvaccinated youth are at risk for HPV infection and associated diseases, and limited research has explored factors associated with HPV vaccination among those who are disadvantaged and at high risk, including lesbian, gay, bisexual, transgender and queer and/or homeless. METHODS: A retrospective electronic medical record review was conducted at an urban, homeless, and lesbian, gay, bisexual, transgender and queer focused health center in northeastern US logistic regression models examined the associations between HPV vaccination and demographic/social characteristics and health behaviors...
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27835628/herpes-simplex-virus-type-1-shedding-in-tears-and-nasal-and-oral-mucosa-of-healthy-adults
#16
Meena Ramchandani, Marlene Kong, Elizabeth Tronstein, Stacy Selke, Anna Mikhaylova, Amalia Magaret, Meei-Li Huang, Christine Johnston, Lawrence Corey, Anna Wald
BACKGROUND: Herpes simplex virus type 1 (HSV-1) is prevalent worldwide and causes mucocutaneous infections of the oral area. We aimed to define the frequency and anatomic distribution of HSV-1 reactivation in the facial area in persons with a history of oral herpes. METHODS: Eight immunocompetent HSV-1 seropositive adults were evaluated for shedding of HSV-1 from 12 separate orofacial sites (8 from oral mucosa, 2 from nose, and 2 from conjunctiva) 5 days a week and from the oral cavity 7 days a week for approximately 5 consecutive weeks by a HSV DNA PCR assay...
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27835627/intravaginal-practices-and-prevalence-of-sexual-and-reproductive-tract-infections-among-women-in-rural-malawi
#17
Allahna Esber, Nisha Rao, Alison Norris, Patricia Carr Reese, Jonathan Kandodo, Patrick Nampandeni, Enock Jumbe, Abigail Norris Turner
BACKGROUND: Many women engage in intravaginal practices (IVP) with a goal of improving genital hygiene and increasing sexual pleasure. Intravaginal practices can disrupt the genital mucosa, and some studies have found that IVP increases risk of acquisition of HIV and bacterial vaginosis (BV). Limited prior research also suggests significant associations between IVP, herpes simplex virus type 2 (HSV-2), and high-risk types of human papillomavirus (HPV). METHODS: We examined associations between IVP and HPV, BV, and HSV-2 among 200 women in rural Malawi participating in a clinic-based study on sexual and reproductive tract infections...
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27835626/genotype-specific-concordance-of-chlamydia-trachomatis-genital-infection-within-heterosexual-partnerships
#18
Julia A Schillinger, Barry P Katz, Lauri E Markowitz, Phillip G Braslins, Lydia A Shrier, Guillermo Madico, Barbara Van Der Pol, Donald P Orr, Peter A Rice, Byron E Batteiger
BACKGROUND: Sexual transmission rates of Chlamydia trachomatis (Ct) cannot be measured directly; however, the study of concordance of Ct infection in sexual partnerships (dyads) can help to illuminate factors influencing Ct transmission. METHODS: Heterosexual men and women with Ct infection and their sex partners were enrolled and partner-specific coital and behavioral data collected for the prior 30 days. Microbiological data included Ct culture, and nucleic acid amplification testing (NAAT), quantitative Ct polymerase chain reaction, and ompA genotyping...
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27835625/use-of-treponemal-screening-assay-strength-of-signal-to-avoid-unnecessary-confirmatory-testing
#19
Gregory J Berry, Michael J Loeffelholz
BACKGROUND: Our reverse syphilis testing algorithm consists of a treponemal IgG multiplex flow immunoassay (MFI) followed by both rapid plasma reagin titer and the Treponema pallidum particle agglutination (TPPA) test on specimens with a reactive MFI result. We report here the impact of a modified reverse algorithm, in which the strength of signal of the MFI is used to avoid unnecessary TPPA testing. METHODS: The Bioplex syphilis IgG MFI was used as the syphilis screening assay, and specimens with equivocal (antibody index 0...
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27835624/cuba-validated-as-the-first-country-to-eliminate-mother-to-child-transmission-of-human-immunodeficiency-virus-and-congenital-syphilis-lessons-learned-from-the-implementation-of-the-global-validation-methodology
#20
Sonja Caffe, Freddy Perez, Mary L Kamb, Rodolfo Gomez Ponce de Leon, Monica Alonso, Ralph Midy, Lori Newman, Chika Hayashi, Massimo Ghidinelli
No abstract text is available yet for this article.
December 2016: Sexually Transmitted Diseases
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