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Sexually Transmitted Diseases

Lao-Tzu Allan-Blitz, Olivia L Ellis, Robert Bolan, Peera Hemarajata, Romney M Humphries, Akbar Shahkolahi, Mark McGrath, Jeffrey D Klausner
No abstract text is available yet for this article.
September 13, 2018: Sexually Transmitted Diseases
Benjamin O Weger, David A Klein, Barbara L Bowsher, Larissa F Weir, Timothy A Roberts
The CDC suggests screening for Trichomonas vaginalis infection might be considered in high prevalence populations. High asymptomatic infection rates and poor sensitivity of clinical diagnosis make it difficult to estimate local prevalence. Testing of ThinPrep samples can provide an estimate of local Trichomonas vaginalis infection rates and guide screening practices.
September 13, 2018: Sexually Transmitted Diseases
Mohammad M Rahman, Ashley Hoover, Chaquetta Johnson, Thomas A Peterman
BACKGROUND: Louisiana has had the highest rates of congenital syphilis (CS) in the nation since 2012. CS Case Review Boards were established statewide in 2016 to study CS cases and identify interventions. METHODS: We summarized the findings of CS review boards, assessed which cases were preventable by prenatal care providers, reviewed recommended interventions, and assessed subsequent improvement in provider practices. RESULTS: All 79 CS cases reported January 2016-July 2017 were reviewed by boards during August 2016-August 2017...
August 31, 2018: Sexually Transmitted Diseases
Anna B Cope, Victoria L Mobley, Sara E Oliver, Mara Larson, Nicole Dzialowy, Jason Maxwell, Jessica L Rinsky, Thomas A Peterman, Aaron Fleischauer, Erika Samoff
BACKGROUND: Ocular syphilis (OS) has been associated with HIV coinfection previously. We compared demographic and clinical characteristics of syphilis patients with and without HIV to identify risk factors for developing OS. METHODS: We reviewed all syphilis cases (early and late) reported to the North Carolina (NC) Division of Public Health during 2014-2016 and categorized HIV status (positive, negative, unknown) and OS status based on report of ocular symptoms with no other defined etiology...
August 31, 2018: Sexually Transmitted Diseases
Elizabeth Micks, Hyunju Son, Amalia Magaret, Stacy Selke, Christine Johnston, Anna Wald
BACKGROUND: The effect of female sex hormones on HSV-2 shedding and lesion frequency is poorly understood. Previous studies suggest that hormonal contraception may increase the frequency of HSV-2 shedding. METHODS: We studied HSV-2 seropositive women who performed daily genital swabbing for HSV DNA and completed diaries for genital lesions and menses. We used Poisson mixed effects models to determine if HSV detection varied throughout the menstrual cycle, or in response to hormonal contraception...
August 24, 2018: Sexually Transmitted Diseases
Erica M Lokken, Barbra A Richardson, John Kinuthia, Khamis Mwinyikai, Amina Abdalla, Walter Jaoko, Kishorchandra Mandaliya, Juma Shafi, R Scott McClelland
BACKGROUND: Some studies suggest that higher body mass index is associated with increased susceptibility to bacterial vaginosis (BV), but results are conflicting. METHODS: Female sex workers aged 16-45 and participating in an open, prospective cohort study in Mombasa, Kenya between 2000 and 2014 were included in this analysis. Up to 2 years of follow-up were included per woman. Body mass index (BMI) was categorized as underweight (≤18.5), normal (18.5-24.9), overweight (25-29...
August 24, 2018: Sexually Transmitted Diseases
Susan Cha, Daniel R Newman, Mohammad Rahman, Thomas A Peterman
BACKGROUND: Chlamydial infections are common among young women and can lead to serious reproductive health complications. We assessed the risk of reported repeat chlamydial infection among young women in Louisiana and time interval between infections by age and race/ethnicity. METHODS: We analyzed surveillance data on chlamydial infections reported among women in Louisiana from January 1, 2000 to December 31, 2015. Multiple reports for the same person were matched using unique codes...
August 24, 2018: Sexually Transmitted Diseases
Linda M Niccolai, Kim M Blankenship, Danya E Keene
BACKGROUND: Housing instability is linked to numerous health outcomes, but the specific impact of eviction from renter-occupied households, an event that has immediate implications for residential stability for low-income individuals, on sexually transmitted infections (STI) rates has not been adequately studied. METHODS: We examined county-level associations between eviction rates in 2014 and rates of chlamydia and gonorrhea in the following year using publicly available data sources (Eviction Lab National Database and AtlasPlus, respectively)...
August 24, 2018: Sexually Transmitted Diseases
Mira Henien, Paul Nyirjesy, Katharine Smith
No abstract text is available yet for this article.
August 14, 2018: Sexually Transmitted Diseases
Gweneth B Lazenby, Lauren Thompson, Anna M Powell, David E Soper
BACKGROUND: Our primary objective was to determine the rate of persistent Trichomonas infection among pregnant women post-treatment. The secondary objective was to determine if oral multi-dose metronidazole was associated with fewer cases of persistent Trichomonas compared to single dose treatment. METHODS: This is a retrospective cohort study of women diagnosed with genital Trichomonas vaginalis from 2008-17. We calculated the rate of persistent Trichomonas by dividing the number of positive Trichomonas tests collected ≥ 21 days post-treatment by the total number of women treated and retested...
July 31, 2018: Sexually Transmitted Diseases
Matthew M Hamill, Louise Seppings, Vivienne Kit, Sheelah Antao
We believe this to be the first report of co-existing PCR-confirmed primary genital and ocular syphilis in a patient with penicillin allergy treated with doxycycline. The case examines the use of non-penicillin and corticosteroid treatment of ocular syphilis and highlights the risk of eye involvement early in the disease process.
July 24, 2018: Sexually Transmitted Diseases
Aaron Louette, Jessica Krahn, Vera Caine, Shalane Ha, Tim T Y Lau, Ameeta E Singh
A systematic review of studies completed in the last eleven years for the treatment of acute epididymitis identified 1534 records of which 29 were assessed for eligibility, and only one study met criteria for inclusion. This highlights the need for more prospective studies evaluating treatment regimens for acute epididymitis.
July 24, 2018: Sexually Transmitted Diseases
Thomas A Peterman, Sarah E Kidd
BACKGROUND: Before penicillin, the syphilis case-fatality rate was 10% within 40 years. Late complications, such as cardiovascular syphilis, were still common in the 1950s but now seem quite rare even though some infections likely go undetected. We studied trends in syphilis mortality as an indicator of trends in severe complications of syphilis. METHODS: We assessed underlying cause of death from U.S. death certificates for 1968-2015. We examined death trends by type of syphilis (cardiovascular, neuro, congenital, other)...
July 24, 2018: Sexually Transmitted Diseases
Guoyu Tao, Kristen Kreisel, Thomas L Gift
We examined Medicaid claims data during 2004-2013. The proportion of sexually-active females aged 15-25 years who had Pap testing or were pregnant significantly decreased during 2004-2013 (67.0% to 43.9%, p<0.05), resulting in a slowed increasing trend in overall chlamydia screening rates. Structural-level interventions for improving chlamydia screening are urgently needed.
July 24, 2018: Sexually Transmitted Diseases
Thomas L Gift, Kendra M Cuffe, Jami S Leichliter
Staffing reductions in state (SHD) and local health departments (LHD) in fiscal year 2012 were concentrated in disease investigation specialists (DIS) and clinicians (local) and DIS and administrative staff (state). LHDs with budget cuts, were significantly more likely to report reduced partner services if they had staffing reductions.
July 24, 2018: Sexually Transmitted Diseases
Jillian Pintye, Benson Singa, Kennedy Wanyonyi, Janet Itindi, John Kinuthia, Agnes Langat, Lucy Nganga, Abraham Katana, Jared Baeten, Christine J McGrath, Grace C John-Stewart
Antenatal register data from 62 clinics in 5 regions of Kenya were used to estimate women with HIV risk (partner HIV status, syphilis). With individual risk-guided PrEP offer in all regions, 39% of pregnant women nationally would be offered PrEP. PrEP offer to all women in high prevalence regions would result in 26%.
July 24, 2018: Sexually Transmitted Diseases
Samuel M Jenness, Kevin M Weiss, Pragati Prasad, Maria Zlotorzynska, Travis Sanchez
BACKGROUND: Prevention of bacterial STIs among men who have sex with men (MSM) requires timely disease detection, but this is complicated by asymptomatic infection. We estimated screening/testing rates by symptomatic status to evaluate adherence to CDC STI screening guidelines. METHODS: In a cross-sectional study of 2572 US MSM aged 15-65 in 2017-2018, we measured the reported number of asymptomatic STI screens in the past 2 years versus tests prompted by disease symptoms...
July 24, 2018: Sexually Transmitted Diseases
Sara Belga, Jennifer Gratrix, Petra Smyczek, M N Lindsay Bertholet, Ron Read, Kelsey Roelofs, Ameeta Singh
BACKGROUND: A case of gonococcal conjunctivitis (GC) prompted us to review the reported cases and treatment regimens of gonococcal conjunctivitis in Alberta, Canada. METHODS: Gonococcal cases reported from 2000 to 2016 were extracted from the provincial STI reporting database. The diagnosis of GC was based on a positive culture and/or nucleic acid amplification test from the eye. RESULTS: A total of 45 cases of GC were reported in adults. Three-quarters (75...
July 24, 2018: Sexually Transmitted Diseases
Eugene W Liu, Kimberly A Workowski, Laura Taouk, Jay Schulkin, William E Secor, Jeffrey L Jones
PURPOSE: Trichomoniasis is the most prevalent non-viral sexually transmitted infection in the United States. It can present with vaginitis in women and urethritis in men, but is most often asymptomatic or occurs with minimal symptoms. It is associated with other sexually transmitted infections (STIs), adverse pregnancy outcomes and pelvic inflammatory disease. For these reasons, healthcare provider awareness of trichomoniasis is of public health importance. METHODS: To assess practitioner knowledge, attitudes, and practices concerning trichomoniasis management, the American College of Obstetricians and Gynecologists (ACOG) conducted an online survey in 2016 of its members, and we analyzed results from 230 respondents...
July 7, 2018: Sexually Transmitted Diseases
Li Xiao, Ken B Waites, Barbara Van Der Pol, Kristal J Aaron, Edward W Hook, William M Geisler
BACKGROUND: Mycoplasma genitalium (MG) is a sexually transmitted pathogen associated with inflammatory syndromes in men and women. Macrolides and fluoroquinolones are recommended MG treatments. The frequency of MG strains with macrolide resistance-associated mutations (MRMs) and quinolone resistance-associated mutations (QRMs) is increasing worldwide, however these data are sparse in populations in the US. METHODS: We investigated the prevalence of MG infections with MRMs and QRMs and MG infection concordance within African American couples in Birmingham, Alabama...
July 3, 2018: Sexually Transmitted Diseases
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