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Medical & Biological Engineering & Computing

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https://www.readbyqxmd.com/read/29238903/a-time-local-subset-feature-selection-for-prediction-of-sudden-cardiac-death-from-ecg-signal
#1
Elias Ebrahimzadeh, Mohammad Sajad Manuchehri, Sana Amoozegar, Babak Nadjar Araabi, Hamid Soltanian-Zadeh
Prediction of sudden cardiac death continues to gain universal attention as a promising approach to saving millions of lives threatened by sudden cardiac death (SCD). This study attempts to promote the literature from mere feature extraction analysis to developing strategies for manipulating the extracted features to target improvement of classification accuracy. To this end, a novel approach to local feature subset selection is applied using meticulous methodologies developed in previous studies of this team for extracting features from non-linear, time-frequency, and classical processes...
December 14, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29235056/separating-arterial-pressure-increases-and-decreases-in-assessing-cardiac-baroreflex-sensitivity-via-sequence-and-bivariate-phase-rectified-signal-averaging-techniques
#2
Beatrice De Maria, Vlasta Bari, Marco Ranucci, Valeria Pistuddi, Giovanni Ranuzzi, Anielle C M Takahashi, Aparecida M Catai, Laura Dalla Vecchia, Sergio Cerutti, Alberto Porta
Cardiac baroreflex (cBR) is activated by both arterial pressure (AP) increases and decreases. Sequence method, a widely utilized tool assessing cBR sensitivity (cBRS) from spontaneous heart period (HP) and systolic AP (SAP) variations, allows the separated computation of cBRS from positive and negative SAP variations. The recently proposed phase-rectified signal averaging (PRSA) method has the same feature but it has been applied so far solely to positive SAP variations. We adapted the PRSA method to compute cBRS over negative SAP variations and we compared the results with those derived from sequence method over two protocols: (i) graded head-up tilt (HUT) at 15, 30, 45, 60, and 75° in 19 healthy subjects and (ii) general anesthesia induction in 118 patients undergoing coronary artery bypass graft surgery...
December 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29235055/a-finite-element-model-to-assess-transtibial-prosthetic-sockets-with-elastomeric-liners
#3
John C Cagle, Per G Reinhall, Kate J Allyn, Jake McLean, Paul Hinrichs, Brian J Hafner, Joan E Sanders
People with transtibial amputation often experience skin breakdown due to the pressures and shear stresses that occur at the limb-socket interface. The purpose of this research was to create a transtibial finite element model (FEM) of a contemporary prosthesis that included complete socket geometry, two frictional interactions (limb-liner and liner-socket), and an elastomeric liner. Magnetic resonance imaging scans from three people with characteristic transtibial limb shapes (i.e., short-conical, long-conical, and cylindrical) were acquired and used to develop the models...
December 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29222614/a-singular-k-space-model-for-fast-reconstruction-of-magnetic-resonance-images-from-undersampled-data
#4
Jianhua Luo, Zhiying Mou, Binjie Qin, Wanqing Li, Philip Ogunbona, Marc C Robini, Yuemin Zhu
Reconstructing magnetic resonance images from undersampled k-space data is a challenging problem. This paper introduces a novel method of image reconstruction from undersampled k-space data based on the concept of singularizing operators and a novel singular k-space model. Exploring the sparsity of an image in the k-space, the singular k-space model (SKM) is proposed in terms of the k-space functions of a singularizing operator. The singularizing operator is constructed by combining basic difference operators...
December 9, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29218511/optical-monitoring-of-cerebral-microcirculation-in-neurointensive-care
#5
Peter Rejmstad, Neda Haj-Hosseini, Oscar Åneman, Karin Wårdell
Continuous optical monitoring of local cerebral microcirculation could benefit neurointensive care patients treated for subarachnoid hemorrhage (SAH). The aim of the study was to evaluate laser Doppler flowmetry (LDF) and diffuse reflectance spectroscopy (DRS) for long-term monitoring of brain microcirculation and oxygen saturation (SO2) in the neurointensive care unit (NICU). A fiber optic probe was designed for intraparenchymal use and connected to LDF and DRS for assessment of the local blood flow (perfusion and tissue reflectance (TLI)) and SO2 in the brain...
December 8, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29214465/the-peripheral-soft-tissues-should-not-be-ignored-in-the-finite-element-models-of-the-human-knee-joint
#6
Hamid Naghibi Beidokhti, Dennis Janssen, Sebastiaan van de Groes, Nico Verdonschot
In finite element models of the either implanted or intact human knee joint, soft tissue structures like tendons and ligaments are being incorporated, but usually skin, peripheral knee soft tissues, and the posterior capsule are ignored and assumed to be of minor influence on knee joint biomechanics. It is, however, unknown how these peripheral structures influence the biomechanical response of the knee. In this study, the aim was to assess the significance of the peripheral soft tissues and posterior capsule on the kinematics and laxities of human knee joint, based on experimental tests on three human cadaveric specimens...
December 7, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29209962/effects-of-location-and-extent-of-spine-clustering-on-synaptic-integration-in-striatal-medium-spiny-neurons-a-computational-study
#7
Mrunal Rane, Rohit Manchanda
The nucleus accumbens (NAc) is known widely for its role in the reward circuit, which is dysregulated in a number of psychological disorders. Recent evidence also suggests the contribution of this structure in spatial and gustatory memories. Because of its role in different types of memories, similar to the hippocampus, we assumed the formation of spine clusters, which are engrams of memory, to be present on dendrites of medium spiny neurons (MSNs). We found that the activation of clustered inputs resulted in sublinear summation when clusters were present on the same branch and also when inputs were distributed on different branches...
December 6, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29209961/finite-element-analysis-of-the-wrist-in-stroke-patients-the-effects-of-hand-grip
#8
Muhammad Hanif Ramlee, Gan Kok Beng, Nazri Bajuri, Mohammed Rafiq Abdul Kadir
The provision of the most suitable rehabilitation treatment for stroke patient remains an ongoing challenge for clinicians. Fully understanding the pathomechanics of the upper limb will allow doctors to assist patients with physiotherapy treatment that will aid in full arm recovery. A biomechanical study was therefore conducted using the finite element (FE) method. A three-dimensional (3D) model of the human wrist was reconstructed using computed tomography (CT)-scanned images. A stroke model was constructed based on pathological problems, i...
December 5, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29199363/development-and-preclinical-trials-of-a-wire-driven-end-effector-device-for-frozen-shoulder-treatment
#9
Chul Min Park, Seong-Il Kwon, Hanpyo Hong, Sungchul Kang, In-Ho Jeon, Shinsuk Park, Keri Kim
Several different flexible end effectors have been developed to solve the problem of approaching the lesion in a minimally invasive surgery. In this paper, we developed a wire-driven end effector device to treat frozen shoulder. Since the device is for capsular release surgery, it has a suitable bend radius for the surgery. It is a cylindrical cannula that can fit various surgical tools and can be sterilized after use. The end effector is made of an elastic material called PAI (polyamide-imide) with its outer diameter and total length being 4 and 19 mm...
December 4, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29192382/multimodal-molecular-3d-imaging-for-the-tumoral-volumetric-distribution-assessment-of-folate-based-biosensors
#10
Gerardo J Ramírez-Nava, Clara L Santos-Cuevas, Isaac Chairez, Liliana Aranda-Lara
The aim of this study was to characterize the in vivo volumetric distribution of three folate-based biosensors by different imaging modalities (X-ray, fluorescence, Cerenkov luminescence, and radioisotopic imaging) through the development of a tridimensional image reconstruction algorithm. The preclinical and multimodal Xtreme imaging system, with a Multimodal Animal Rotation System (MARS), was used to acquire bidimensional images, which were processed to obtain the tridimensional reconstruction. Images of mice at different times (biosensor distribution) were simultaneously obtained from the four imaging modalities...
December 1, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29181625/development-of-a-high-resolution-infrared-thermographic-imaging-method-as-a-diagnostic-tool-for-acute-undifferentiated-limp-in-young-children
#11
R Owen, S Ramlakhan, R Saatchi, D Burke
Acute limp is a common presenting condition in the paediatric emergency department. There are a number of causes of acute limp that include traumatic injury, infection and malignancy. These causes in young children are not easily distinguished. In this pilot study, an infrared thermographic imaging technique to diagnose acute undifferentiated limp in young children was developed. Following required ethics approval, 30 children (mean age = 5.2 years, standard deviation = 3.3 years) were recruited. The exposed lower limbs of participants were imaged using a high-resolution thermal camera...
November 28, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29178064/deblurring-sequential-ocular-images-from-multi-spectral-imaging-msi-via-mutual-information
#12
Jian Lian, Yuanjie Zheng, Wanzhen Jiao, Fang Yan, Bojun Zhao
Multi-spectral imaging (MSI) produces a sequence of spectral images to capture the inner structure of different species, which was recently introduced into ocular disease diagnosis. However, the quality of MSI images can be significantly degraded by motion blur caused by the inevitable saccades and exposure time required for maintaining a sufficiently high signal-to-noise ratio. This degradation may confuse an ophthalmologist, reduce the examination quality, or defeat various image analysis algorithms. We propose an early work specially on deblurring sequential MSI images, which is distinguished from many of the current image deblurring techniques by resolving the blur kernel simultaneously for all the images in an MSI sequence...
November 25, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29178063/evaluation-of-the-performance-of-three-tenodesis-techniques-for-the-treatment-of-scapholunate-instability-flexion-extension-and-radial-ulnar-deviation
#13
Teresa Alonso-Rasgado, Qing-Hang Zhang, David Jimenez-Cruz, Colin Bailey, Elizabeth Pinder, Avanthi Mandaleson, Sumedh Talwalkar
Chronic scapholunate ligament (SL) injuries are difficult to treat and can lead to wrist dysfunction. Whilst several tendon reconstruction techniques have been employed in the management of SL instability, SL gap reappearance after surgery has been reported. Using a finite element model and cadaveric study data, we investigated the performance of the Corella, scapholunate axis (SLAM) and modified Brunelli tenodesis (MBT) techniques. Scapholunate dorsal and volar gap and angle were obtained following virtual surgery undertaken using each of the three reconstruction methods with the wrist positioned in flexion, extension, ulnar deviation and radial deviation, in addition to the ulnar-deviated clenched fist and neutral positions...
November 25, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29150800/beat-to-beat-estimation-of-stroke-volume-using-impedance-cardiography-and-artificial-neural-network
#14
S M M Naidu, Prem C Pandey, Uttam R Bagal, Suhas P Hardas
Impedance cardiography is a low-cost noninvasive technique, based on monitoring of the thoracic impedance, for estimation of stroke volume (SV). Impedance cardiogram (ICG) is the negative of the first derivative of the impedance signal. A technique for beat-to-beat SV estimation using impedance cardiography and artificial neural network (ANN) is proposed. A three-layer feed-forward ANN with error back-propagation algorithm is optimized by examining the effects of number of neurons in the hidden layer, activation function, training algorithm, and set of input parameters...
November 18, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29150799/a-hybrid-approach-based-on-logistic-classification-and-iterative-contrast-enhancement-algorithm-for-hyperintense-multiple-sclerosis-lesion-segmentation
#15
Antonio Carlos da Silva Senra Filho
Multiple sclerosis (MS) is a neurodegenerative disease with increasing importance in recent years, in which the T2 weighted with fluid attenuation inversion recovery (FLAIR) MRI imaging technique has been addressed for the hyperintense MS lesion assessment. Many automatic lesion segmentation approaches have been proposed in the literature in order to assist health professionals. In this study, a new hybrid lesion segmentation approach based on logistic classification (LC) and the iterative contrast enhancement (ICE) method is proposed (LC+ICE)...
November 18, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29147835/automatic-localization-of-the-left-ventricular-blood-pool-centroid-in-short-axis-cardiac-cine-mr-images
#16
Li Kuo Tan, Yih Miin Liew, Einly Lim, Yang Faridah Abdul Aziz, Kok Han Chee, Robert A McLaughlin
In this paper, we develop and validate an open source, fully automatic algorithm to localize the left ventricular (LV) blood pool centroid in short axis cardiac cine MR images, enabling follow-on automated LV segmentation algorithms. The algorithm comprises four steps: (i) quantify motion to determine an initial region of interest surrounding the heart, (ii) identify potential 2D objects of interest using an intensity-based segmentation, (iii) assess contraction/expansion, circularity, and proximity to lung tissue to score all objects of interest in terms of their likelihood of constituting part of the LV, and (iv) aggregate the objects into connected groups and construct the final LV blood pool volume and centroid...
November 17, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29134413/comparison-of-feature-evaluation-criteria-for-speech-recognition-based-on-electromyography
#17
Niyawadee Srisuwan, Pornchai Phukpattaranont, Chusak Limsakul
In this paper, we present a performance comparison of 14 feature evaluation criteria and 4 classifiers for isolated Thai word classification based on electromyography signals (EMG) to find a near-optimal criterion and classifier. Ten subjects spoke 11 Thai number words in both audible and silent modes while the EMG signal from five positions of the facial and neck muscles were captured. After signal collection and preprocessing, 22 EMG features widely used in the EMG recognition field were computed and were then evaluated based on 14 evaluation criteria including both independent criteria (IC) and dependent criteria (DC) for feature evaluation and selection...
November 14, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29130138/automated-3d-method-for-the-construction-of-flexible-and-reconfigurable-numerical-breast-models-from-mri-scans
#18
Muhammad Omer, Elise C Fear
Anatomically realistic numerical breast models are essential tools for microwave breast imaging, supporting feasibility analysis, performance verification, and design improvements. Patient-specific models also assist in interpreting the results of the patient studies conducted on microwave imaging prototype systems. The proposed method employs automated and robust 3D processing techniques to construct flexible and reconfigurable breast models. These techniques include noise and artifact suppression with a principal component analysis (PCA) approach, and oversampling of the magnetic resonance imaging (MRI) data to enhance the intensity continuity...
November 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29130137/assessment-of-the-equivalent-dipole-layer-source-model-in-the-reconstruction-of-cardiac-activation-times-on-the-basis-of-bspms-produced-by-an-anisotropic-model-of-the-heart
#19
Arno M Janssen, Danila Potyagaylo, Olaf Dössel, Thom F Oostendorp
Promising results have been reported in noninvasive estimation of cardiac activation times (AT) using the equivalent dipole layer (EDL) source model in combination with the boundary element method (BEM). However, the assumption of equal anisotropy ratios in the heart that underlies the EDL model does not reflect reality. In the present study, we quantify the errors of the nonlinear AT imaging based on the EDL approximation. Nine different excitation patterns (sinus rhythm and eight ectopic beats) were simulated with the monodomain model...
November 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29130136/correction-to-quantitative-topographic-anatomy-of-the-femoral-acl-footprint-a-micro-ct-analysis
#20
Danielle G Norman, Alan Getgood, John Thornby, Jonathan Bird, Glen A Turley, Tim Spalding, Mark A Williams
An author has corrected their first name and updated their email address - see the affiliation section below. Daniel G. Norman should now be Danielle G. Norman as shown in the authorgroup section above.
November 13, 2017: Medical & Biological Engineering & Computing
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