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Gastroentérologie Clinique et Biologique

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https://www.readbyqxmd.com/read/21075574/feasibility-and-safety-of-granulocytapheresis-in-crohn-s-disease-a-prospective-cohort-study
#1
G Bresci, A Romano, A Mazzoni, F Scatena, E Altomare, A Capria, R Sacco
BACKGROUND AND OBJECTIVE: This study evaluated the feasibility and safety of granulocytapheresis (GCAP) in inducing and maintaining remission in refractory Crohn's disease. The relationship between the clinical outcomes and the location (ileal or ileocolonic) of disease was also assessed. PATIENTS: We evaluated 16 patients with ileal location (group A), 14 with ileocolonic location (group B). The patients underwent five sessions (1 session/wk) of GCAP (Adacolumn(TM))...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/21051167/stem-cells-and-colon-cancer-the-questionable-cancer-stem-cell-hypothesis
#2
REVIEW
C Gespach
The fine-tuning between cell proliferation and differentiation of self-renewing stem cells and pluripotent progenitors in gastric glands and colon epithelial crypts is coordinated by the mechanisms that regulate colon epithelial cell migration and guidance along the crypt axis. This leads to the acquisition of specialized cellular functions and the exfoliation of desquamated senescent and apoptotic epithelial cells at the apical mucosa interface with the gut lumen. Self-renewing stem cells and pluripotent progenitors are involved in the clonal and polyclonal growth of digestive tumors...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20971590/therapeutic-apheresis-from-the-early-civilizations-to-the-twenty-first-century
#3
EDITORIAL
A R Saniabadi, H Hanai
No abstract text is available yet for this article.
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20970937/heterotopic-pancreas-an-unusual-cause-of-epigastric-pain
#4
LETTER
S Reggoug, I Errabih, L Ouazzani, N Benzzoubeir, H Krami, M Raiss, A Hrora, M Ahallat, H Ouazzani
No abstract text is available yet for this article.
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20970271/colonoscopy-practices-and-colorectal-cancer-and-polyp-screening-as-assessed-in-the-french-district-of-is%C3%A3-re-from-may-to-july-in-2004
#5
C Exbrayat, F Poncet, A Billette de Villemeur, A Garnier, P Bureau du Colombier
BACKGROUND: A pilot program of organized screening for colorectal cancers was conducted in Isère, an administrative district in France. A fecal occult blood test (Hemoccult II(®)) was proposed for all individuals aged greater than 50 years (women since 1991 and men since 2002), followed by colonoscopy for those testing positive. A prospective study was carried out from May to July in 2004 and compared with a similar study conducted in 1996. The goal was to investigate colonoscopy practices, especially the role of screening...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20934290/transcatheter-local-thrombolysis-in-patients-with-extensive-tips-thrombosis
#6
J Dumortier, T Walter, O Guillaud, F Pietu, M Vallin, L Henry, F Pilleul
BACKGROUND: Transcatheter local thrombolytic therapy in patients with portosplanchnic venous thrombosis has been used in few cases. CASE REPORTS: Here, we present our single-center experience with transcatheter thrombolytic therapy in three patients with extensive refractory portal and transjugular intrahepatic portosystemic shunt (TIPS) thrombosis. Thrombolytic therapy was successful for all three patients. Two patients developed minor procedure-related bleeding...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20934287/clinical-and-endoscopic-features-of-responders-and-non-responders-to-adsorptive-leucocytapheresis-a-report-based-on-120-patients-with-active-ulcerative-colitis
#7
Tomotaka Tanaka, Hideharu Okanobu, Yoshio Kuga, Yoshikazu Yoshifuku, Hatsue Fujino, Tomohiro Miwata, Takashi Moriya, Toshihiro Nishida, Toshihide Oya
BACKGROUND AND OBJECTIVE: Elevated/activated myeloid leucocytes, like the CD14(+)CD16(+) monocytes are sources of TNF-α, and therefore, selective depletion of these cells by granulocyte/monocyte (GM) adsorption (GMA) should promote remission or enhance drug efficacy. However, studies in ulcerative colitis (UC) reported contrasting efficacy, from an 85% to statistically insignificant level. We investigated patients' demography in responders and non-responders. METHODS: In 120 UC patients, 61 steroid naive and 59 steroid dependent, we looked for entry clinical or endoscopic features to identify responders (or non-responders) to GMA...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20884146/multiple-intestinal-perforation-in-a-patient-with-wegener-s-granulomatosis-a-case-report-and-review-of-the-literature
#8
REVIEW
A C Yildirim, E Koçak, P Yildiz, M Yildiz, A Ş Karakayali, B Kaptanoglu, S Köklü
Wegener's granulomatosis is a necrotizing vasculitis of unknown etiology characterized mainly by inflammation of the small- and medium-sized arteries and veins that affect any viscera. It may rarely involve the gastrointestinal tract. Only a few cases of multiple focus ileal perforation due to ulcers associated with Wegener's granulomatosis have been reported. Herein we report a case of a 32-year-old man with extensive intestinal small bowel ischaemic perforation due to Wegener's granulomatosis.
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20864281/a-not-so-solitary-fibrous-tumor-of-the-liver
#9
C Brochard, S Michalak, C Aubé, C Singeorzan, H-D Fournier, L Laccourreye, P Calès, J Boursier
Solitary fibrous tumor (SFT) is a rare neoplasm. Liver parenchyma is a rare location of SFT and, in this case, it usually follows a benign course. We report here the case of a 54-year-old man who presented a large SFT tumor of the right hepatic lobe. The tumor was surgically resected. Local recurrence occurred 6 years later as a 15 cm diameter liver tumor. Histological examination of the resected lesion showed features of an aggressive form of SFT. Two years later, the patient presented with complaints of neck pain and ensuing examinations revealed a tumor of the cranial base...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20832215/circulating-free-tumor-dna-and-colorectal-cancer
#10
T Lecomte, N Ceze, E Dorval, P Laurent-Puig
Cancer is characterized by multiple somatic genetic and epigenetic alterations that could be useful as molecular markers for detecting tumor DNA in different bodily fluids. In patients with various diseases as well as in healthy subjects, circulating plasma and serum carry small amounts of non-cell-bound DNA. In this free circulating DNA, tumor-associated molecular alterations can be detected in patients who have cancer. In many instances, the alterations identified are the same as those found in the primary tumor tissue, thereby suggesting tumor origin from a fraction of the circulating free DNA...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20828955/acute-colonic-pseudo-obstruction
#11
A Akhaddar, M Boucetta
No abstract text is available yet for this article.
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20813475/multinodular-fatty-sparing
#12
M Garetier, C Delluc, J Rousset, S Chinellato, C Sandillon-Garetier, J-A Bronstein
No abstract text is available yet for this article.
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20810228/abdominal-lymphatic-tuberculosis-and-portal-hypertension
#13
A S Bhalla, S Hari, S H Chandrashekhara, A Sinha, G Makharia, R Gupta
Abdominal tuberculosis involving the portal vasculature is a rare phenomenon. We retrospectively reviewed the imaging findings of 183 cases of abdominal tuberculosis at our institution from 2002 to 2010 and found thrombosis of the splenoportal axis associated with abdominal lymphadenopathy in seven patients. However, there was no relationship between the lymph nodal size and development of thrombosis. Reversibility was noted in one patient, who had near complete recanalisation of portal vein. Mechanisms, other than direct mass effect on the splenoportal axis, may be involved, like contiguous spread of inflammation or granulomas in the vessel wall...
December 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/21051169/expected-increase-in-prevalence-of-hcv-related-cirrhosis-and-its-complications-in-the-united-states-no-effect-of-current-antiviral-treatment-coverage
#14
COMMENT
S Deuffic-Burban
Davis et al. projected the future prevalence of chronic hepatitis C (CHC) and its complications in the United States, using a multicohort natural history model with a tree model. First, the model predicted that in 2010 many patients have already progressed to F4, including to decompensated cirrhosis and HCC. Second, the model emphasized that cirrhosis and its complications are most common after 60 years old, regardless of when the infection occurred. Finally, the model showed that current treatment patterns will have little effect on the incidence of the complications hepatitis C...
November 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/21051168/chronic-anemia-resistant-to-erythropoietin-in-a-patient-treated-with-gemcitabine-showing-a-hemolytic-uremic-syndrome-hus
#15
LETTER
C Assi, C Lepage, J-L Jouve, C Sgro, L Bedenne
No abstract text is available yet for this article.
November 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/21051166/the-emerging-role-of-internal-rectal-prolapse-in-the-aetiology-of-faecal-incontinence
#16
REVIEW
R Collinson, C Harmston, C Cunningham, I Lindsey
No abstract text is available yet for this article.
November 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/21050688/images-of-the-month-unusual-left-iliac-fossa-pain
#17
R Arora, S H Chandrashekhara
No abstract text is available yet for this article.
November 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/21050687/enteropathy-associated-t-cell-lymphoma-a-review-on-clinical-presentation-diagnosis-therapeutic-strategies-and-perspectives
#18
REVIEW
M-O Chandesris, G Malamut, V Verkarre, B Meresse, E Macintyre, R Delarue, M-T Rubio, F Suarez, B Deau-Fischer, N Cerf-Bensussan, N Brousse, C Cellier, O Hermine
INTRODUCTION: Enteropathy-associated T-cell lymphoma (EATL) is a rare complication of celiac disease (<1% of lymphomas) and has a poor prognosis. METHODS: International literature review with PubMed search (up to January 2009) of pathophysiological, clinical and therapeutic data. RESULTS: EATL is found in patients with a mean age of 59 years, often with a complication that signals its diagnosis. Refractory celiac disease (RCD), equivalent to low-grade intraepithelial T-cell lymphoma, could be an intermediary between celiac disease and high-grade invasive T-cell lymphoma...
November 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/21036500/image-of-the-month-hepatic-visceral-larva-migrans-due-to-toxocara-canis
#19
S H Chandrashekhara, R Sharma, S Bagh, P Garg
No abstract text is available yet for this article.
November 2010: Gastroentérologie Clinique et Biologique
https://www.readbyqxmd.com/read/20980114/polycythemia-and-elevated-serum-erythropoietin-associated-with-a-liver-haemangioma
#20
Jean-Sébastien Lanne, Jérôme Dumortier, Valérie Hervieu, Frank Pilleul, Jean-Yves Scoazec, Mustapha Adham
BACKGROUND: Secondary polycythemia is a rare condition, which is usually associated to neoplasia or chronic pulmonary disorders. CASE REPORT: A 41-year-old man man with no history of liver disease was admitted for erythrocytosis. The paraclinical investigations revealed an increased erythropoietin level in the serum and a voluminous hepatic tumor but its identification was unclear. A liver resection was performed and the histopathological examination concluded that the tumor was a giant cavernous haemangioma with extensive myxoid changes...
November 2010: Gastroentérologie Clinique et Biologique
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