Tetsuya Urano, Naoki Hayama, Jun Tanaka, Yukihiro Horio, Masako Sato, Shigeaki Hattori, Genki Takahashi, Fuminari Takahashi, Tomoe Takeuchi, Kazuki Harada, Hiroto Takiguchi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Takahisa Takihara, Kyoko Niimi, Tsuyoshi Oguma, Takuya Aoki, Go Ogura, Naoya Nakamura, Koichiro Asano
We report a case of multifocal micronodular pneumocyte hyperplasia (MMPH) in a patient with tuberous sclerosis complex, in whom the lung nodules increased in the number and size over the course of 8 years. We diagnosed MMPH following a lung biopsy performed during video-assisted thoracic surgery. In most of the previously reported cases, the number and size of lung nodules is unchanged during the clinical course. Our case is the first report of progressive disease in pathologically proven MMPH.
December 20, 2016: Tokai Journal of Experimental and Clinical Medicine