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Current Problems in Cardiology

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https://www.readbyqxmd.com/read/30173910/risk-reduction-to-disease-management-clinical-pharmacists-as-cardiovascular-care-providers
#1
REVIEW
Katherine E Di Palo, Khusbu Patel, Troy Kish
Most cardiovascular diseases are caused by modifiable risk factors yet prevalence continues to increase and heart disease remains the leading cause of death in the United States. Screening, identifying and appropriately managing high risk patients are strategies to shift the paradigm from treatment to prevention. Pharmacists are an underutilized population health resource despite robust evidence to support their roles as interdisciplinary team members and direct patient care providers in both inpatient and outpatient settings...
August 4, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30193747/atrial-fibrillation-and-deterioration-in-cognitive-function
#2
REVIEW
Viswanatha Chinta, Sameh Askandar, Amit Nanda, Arindam Sharma, Peter Abader, Rajesh Kabra, Rami N Khouzam
The link between atrial fibrillation and cognitive decline and dementia has gained interest of the medical community lately. More research is being conducted to prevent and or delay this morbidity as no curative therapy is available for cognitive decline and dementia. The exact mechanism of causation is unclear. Multiple pathophysiological mechanisms have been implicated. Lately, treatment for atrial fibrillation including anticoagulation and catheter ablation therapies have shown to decrease the risk of deterioration of cognitive function...
July 11, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30185374/empowering-the-aging-with-mobile-health-a-mhealth-framework-for-supporting-sustainable-healthy-lifestyle-behavior
#3
REVIEW
Anthony Faiola, Elizabeth Lerner Papautsky, Miriam Isola
Healthcare providers are shifting to a value-based model that acknowledges the importance of a healthy lifestyle for managing chronic disease and mental health. This approach empowers patients to adopt and/or sustain healthy lifestyle choices through the use of innovative technologies-providing beneficial ways of delivering health literacy, self-monitoring, and patient-provider collaboration. Such pathways have the potential to enable healthy lifestyle management for a growing U.S. cohort-the "baby boomer" generation (BBG)-who are at risk for developing heart disease, stroke, arthritis, high cholesterol, and diabetes, etc...
July 9, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30195639/sglt-2-inhibitors-and-peripheral-artery-disease-a-statistical-hoax-or-reality
#4
REVIEW
Subhankar Chatterjee, Dhrubajyoti Bandyopadhyay, Raktim K Ghosh, Uddalak Majumdar, Ashish Aneja, Carl J Lavie, Prakash Deedwania
Inhibitors of sodium-glucose cotransporters type-2 are the most recent addition to the armamentarium of oral antidiabetic agents. This class of drugs has shown promising results in glycemic control and most importantly to reduce cardiovascular disease (CVD) mortality risk. Despite the encouraging data, there is concern regarding their potential for causing or worsening peripheral artery disease (PAD), which may increase the risk of lower extremity amputations. Following the publication of results of CANVAS and CANVAS-R trials, which revealed that leg and mid-foot amputations occurred about twice as often in patients treated with canagliflozin compared to placebo, the Food and Drug Administration (FDA) in the United States issued a black box warning of leg and foot amputations associated with canagliflozin use...
July 6, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30217253/foreword
#5
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30196886/foreword
#6
(no author information available yet)
No abstract text is available yet for this article.
September 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29150149/pregnancy-and-heart-disease-pregnancy-associated-hypertension-and-peripartum-cardiomyopathy
#7
Tobias Jonathan Pfeffer, Denise Hilfiker-Kleiner
Cardiovascular diseases are major complications in pregnancy worldwide and the number of patients who develop cardiac problems during pregnancy is increasing. Pregnancy-associated hypertensive complications such as pre-eclampsia (PE) or peripartum cardiomyopathy (PPCM) are potentially life-threatening heart diseases emerging during pregnancy, under delivery or in the first postpartal months in previously healthy women. Both disease entities display substantial morbidity and mortality in the acute phase. Long-term effects are just beginning to be evaluated...
September 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30001780/foreword
#8
(no author information available yet)
No abstract text is available yet for this article.
August 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29290389/treatment-strategies-in-symptomatic-intermediate-low-risk-and-asymptomatic-patients-with-severe-aortic-stenosis
#9
Marko D Banovic, Serge D Nikolic
Survival of symptomatic patients with severe aortic stenosis (AS) is very poor, with an average mortality reaching up to 2% per month. Approach to diagnosis and treatment of patients with AS was conservative; patients were referred to surgery only if the AS-induced symptoms become apparent and significantly limit the quality of patient' life. In the past 15 years, the novel treatment strategy in subgroups of symptomatic patients with AS have been the subject of extensive research, starting from introduction of transcatheter aortic valve implant (TAVI) in inoperable symptomatic patients with severe AS and continuing further to patients with very high and high operative risk...
August 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29174586/aortic-valve-regurgitation-a-comprehensive-review
#10
Oluwaseun A Akinseye, Aradhana Pathak, Uzoma N Ibebuogu
Aortic regurgitation (AR) has an estimated prevalence of 4.9% in the Framingham study, with moderate or severe AR occurring in 0.5% of the study population. The incidence and severity of AR increases with age, and may occur acutely or as a chronic valvular disease with distinct presentations, natural history and management strategy. Our review is a comprehensive description of the varied presentation of aortic regurgitation and its management.
August 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29310997/neurohormonal-imbalance-a-neglected-problem-and-potential-therapeutic-target-in-acute-heart-failure
#11
Steven R Goldsmith, Bradley A Bart, Ileana L Pin A
Decompensated or acute heart failure (AHF) is characterized by increased ventricular and atrial pressures which may lead to and be caused by circulatory congestion. Unless due to a primary decrease in cardiac function, congestion arises from volume expansion or vasoconstriction. In turn, volume expansion and vasoconstriction are due to neurohormonal imbalance since both result from activation of the sympathetic nervous system, the renin-angiotensin-aldosterone axis and excess secretion of arginine vasopressin...
July 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30172551/ultrasonography-in-heart-failure-a-story-that-matters
#12
REVIEW
Chiara Mozzini, Luciano Cominacini, Alder Casadei, Cosima Schiavone, Maurizio Soresi
Heart failure (HF) is a clinical syndrome caused by structural and/or functional cardiac abnormalities, resulting in a reduced cardiac output and/or elevated intracardiac pressures at rest or during stress. It is the leading cause of hospitalization in Internal Medicine departments. This article aims at reviewing evidence of the importance of ultrasound in HF both for hospitalized patients and in the follow-up. Ultrasound may be used as a recovery monitoring instrument at the bedside and also as a global cardiovascular assessment tool for these patients...
June 21, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/30172550/applying-precision-medicine-to-healthy-living-for-the-prevention-and-treatment-of-cardiovascular-disease
#13
Ross Arena, Cemal Ozemek, Deepika Laddu, Tavis Campbell, Codie R Rouleau, Robert Standley, Samantha Bond, Eulàlia P Abril, Andrew P Hills, Carl Lavie
Healthy living medicine (HLM) is an emerging concept that recognizes the importance of: (1) Moving more and sitting less; (2) Consuming a healthy diet at the appropriate caloric load; (3) Maintaining a healthy body weight; and (4) Not smoking. Suffice to say, HLM should be practiced by all health professionals, prescribing a personalized healthy living polypill to individuals under their care while titrating the dosage for optimal adherence and therapeutic efficacy. Traditionally, HLM, particularly when practiced in the context of physical activity and diet, is commonly viewed as an all-or-none and one-size-fits-all paradigm...
June 14, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29759117/current-evidence-based-understanding-of-the-epidemiology-prevention-and-treatment-of-atrial-fibrillation
#14
Paul A Rogers, Michael L Bernard, Christopher Madias, Sudarone Thihalolipavan, N A Mark Estes, Daniel P Morin
Atrial fibrillation (AF) is the most common atrial arrhythmia in adults worldwide. As medical advancements continue to contribute to an ever-increasing aging population, the burden of atrial fibrillation on the modern health care system continues to increase. Therapies are also evolving, for treatment of the arrhythmia itself, and stroke risk mitigation. Internists and cardiologists alike are, in most instances, the frontline contact for AF patients, and would benefit from remaining facile in their understanding of care options...
June 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29784533/long-qt-syndrome-a-comprehensive-review-of-the-literature-and-current-evidence
#15
REVIEW
Syed Raza Shah, Ki Park
Long QT syndrome (LQT) represents a heterogeneous family of cardiac electrophysiologic disorders characterized by QT prolongation and T-wave abnormalities on the electrocardiogram. It is commonly associated with syncope, however, sudden cardiac death can occur due to torsades de pointes. LQT is a clinical diagnosis and should be suspected in individuals on the basis of clinical presentation, family history and electrocardiogram characteristics. Management is focused on the prevention of syncope and ultimately sudden death...
May 10, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29555024/foreword
#16
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29174585/current-trends-and-future-perspectives-in-the-treatment-of-pulmonary-arterial-hypertension
#17
REVIEW
Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, Walter Tan, Timir K Paul
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies of pulmonary arterial hypertension...
May 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29153390/current-trends-and-future-perspectives-in-the-treatment-of-pulmonary-hypertension-who-group-ii-v
#18
REVIEW
Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, Akm Monwarul Islam, Ramesh Daggubati, Timir K Paul
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies of pulmonary hypertension group II-V...
May 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29731112/degenerative-mitral-stenosis-from-pathophysiology-to-challenging-interventional-treatment
#19
REVIEW
Marko Banovic, Mark DaCosta
Mitral stenosis (MS) is characterized by obstruction of left ventricular inflow as a result of narrowing of the mitral valve orifice. Although its prevalence has declined over the last decade, especially in developed countries, it remains an important cause of morbidity and mortality.  The most often cause of MS worldwide is still postrheumatic mitral valve disease. However, in developed countries, degenerative or calcific changes cause MS in a siginificant proportion of patients. Although the range of treatment for mitral valve disease has grown over the years in parallel with transcatheter therapies for aortic valve disease, these improvements in mitral valve disease therapy have experienced slower development...
April 6, 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29530242/let-us-talk-about-moving-reframing-the-exercise-and-physical-activity-discussion
#20
REVIEW
Ross Arena, Amy McNeil, Steven Street, Samantha Bond, Deepika R Laddu, Carl J Lavie, Andrew P Hills
Noncommunicable and chronic disease are interchangeable terms. According to the World Health Organization, "they are of long duration and generally slow progression. The 4 main types of chronic diseases are cardiovascular diseases (ie, heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma), and diabetes." We have known about the benefits of physical activity (PA) for thousands of years. Perhaps our approach, from public health messaging to the individual clinical encounter, as to how PA and exercise are discussed and prescribed can be improved upon, with the ultimate goal of increasing the likelihood that an individual moves more; ultimately moving more should be the goal...
April 2018: Current Problems in Cardiology
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