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Current Problems in Cardiology

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https://www.readbyqxmd.com/read/29310997/neurohormonal-imbalance-a-neglected-problem-and-potential-therapeutic-target-in-acute-heart-failure
#1
Steven R Goldsmith, Bradley A Bart, Ileana L PiƱa
Decompensated or acute heart failure (AHF) is characterized by increased ventricular and atrial pressures which may lead to and be caused by circulatory congestion. Unless due to a primary decrease in cardiac function, congestion arises from volume expansion or vasoconstriction. In turn, volume expansion and vasoconstriction are due to neurohormonal imbalance since both result from activation of the sympathetic nervous system, the renin-angiotensin-aldosterone axis and excess secretion of arginine vasopressin...
December 16, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29290389/treatment-strategies-in-symptomatic-intermediate-low-risk-and-asymptomatic-patients-with-severe-aortic-stenosis
#2
Marko D Banovic, Serge D Nikolic
Survival of symptomatic patients with severe aortic stenosis (AS) is very poor, with an average mortality reaching up to 2% per month. Approach to diagnosis and treatment of patients with AS was conservative; patients were referred to surgery only if the AS-induced symptoms become apparent and significantly limit the quality of patient' life. In the past 15 years, the novel treatment strategy in subgroups of symptomatic patients with AS have been the subject of extensive research, starting from introduction of transcatheter aortic valve implant (TAVI) in inoperable symptomatic patients with severe AS and continuing further to patients with very high and high operative risk...
December 12, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29174586/aortic-valve-regurgitation-a-comprehensive-review
#3
Oluwaseun A Akinseye, Aradhana Pathak, Uzoma N Ibebuogu
Aortic regurgitation (AR) has an estimated prevalence of 4.9% in the Framingham study, with moderate or severe AR occurring in 0.5% of the study population. The incidence and severity of AR increases with age, and may occur acutely or as a chronic valvular disease with distinct presentations, natural history and management strategy. Our review is a comprehensive description of the varied presentation of aortic regurgitation and its management.
November 2, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29153385/foreword
#4
(no author information available yet)
No abstract text is available yet for this article.
November 2, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29174585/current-trends-and-future-perspectives-in-the-treatment-of-pulmonary-arterial-hypertension
#5
Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, Walter Tan, Timir K Paul
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies of pulmonary arterial hypertension...
October 31, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29153390/current-trends-and-future-perspectives-in-the-treatment-of-pulmonary-hypertension-who-group-ii-v
#6
Sukhdeep Bhogal, Debabrata Mukherjee, Subhash Banerjee, Akm Monwarul Islam, Ramesh Daggubati, Timir K Paul
Pulmonary hypertension continues to be a life-threatening illness with debilitating physical and emotional consequences affecting around 1% of global population. The progression of this devastating disease is characterized by increase in pulmonary vascular resistance resulting in elevated pulmonary pressure, eventually leading to right heart failure and death. Better understanding of pathophysiology has led to substantial improvements in terms of availability of treatment options. The purpose of this review is to summarize the currently available treatment options along with pertinent trials and possible future therapies of pulmonary hypertension group II-V...
October 31, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29150149/pregnancy-and-heart-disease-pregnancy-associated-hypertension-and-peripartum-cardiomyopathy
#7
Tobias Jonathan Pfeffer, Denise Hilfiker-Kleiner
Cardiovascular diseases are major complications in pregnancy worldwide and the number of patients who develop cardiac problems during pregnancy is increasing. Pregnancy-associated hypertensive complications such as pre-eclampsia (PE) or peripartum cardiomyopathy (PPCM) are potentially life-threatening heart diseases emerging during pregnancy, under delivery or in the first postpartal months in previously healthy women. Both disease entities display substantial morbidity and mortality in the acute phase. Long-term effects are just beginning to be evaluated...
October 31, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29277221/wearable-cardioverter-defibrillator-the-lifevest-device-design-limitations-and-areas-of-improvement
#8
Manyoo Agarwal, Dennis Narcisse, Nader Khouzam, Rami N Khouzam
Sudden cardiac death is a potentially fatal clinical event demanding use of emergent intervention such as defibrillation. Over the last 1 decade, development of devices such as implantable and wearable cardioverter defibrillators (WCD) has provided new avenues in the management of sudden cardiac death. Several clinical studies have commented on the therapeutic and preventive aspect of WCD, however, literature describing the device functioning and limitations is limited. In this review study, we describe the technical aspects and limitations of WCD with a focus on identifying potential areas of improvement and framework for future research studies...
February 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29277220/foreword
#9
(no author information available yet)
No abstract text is available yet for this article.
February 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29173805/cardiac-amyloidosis-an-updated-review-with-emphasis-on-diagnosis-and-future-directions
#10
Sukhdeep Bhogal, Vatsal Ladia, Puja Sitwala, Emilie Cook, Kailash Bajaj, Vijay Ramu, Carl J Lavie, Timir K Paul
Cardiac amyloidosis occurs because of abnormal protein (amyloid) deposition in the cardiac tissue. Even with advanced diagnostic techniques and treatments, the prognosis of amyloidosis remains poor. The diagnosis of cardiac amyloidosis particularly needs to be in the differential in patients presenting with heart failure with preserved ejection fraction. This entity remains underdiagnosed due to lack of suspicion on the part of many clinicians. Involvement of cardiac tissue is the utmost determinant factor for available treatment options and prognosis...
January 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29110813/duration-of-dual-antiplatelet-therapy-following-drug-eluting-stent-implantation-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#11
Abhishek Sharma, Ofek Hai, Akash Garg, Ajay Vallakati, Carl J Lavie, Jonathan D Marmur
To evaluate the efficacy and safety of long-duration dual antiplatelet therapy (L-DAPT) compared to short-duration dual antiplatelet therapy (S-DAPT) after drug-eluting stent implantation. We searched Medline, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) to identify randomized controlled trials assessing the clinical effect of L-DAPT vs S-DAPT after drug-eluting stent. Efficacy end points were all-cause mortality, cardiac mortality, myocardial infarction (MI), stent thrombosis (ST), and target vessel revascularization (TVR)...
December 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28965561/obesity-and-cardiovasculardiseases
#12
REVIEW
Parham Parto, Carl J Lavie
Obesity has reached epidemic proportions both in the United States and worldwide. There are numerous adverse effects on cardiac structure, hemodynamics, and cellular abnormalities, as well as increases in cardiovascular disease (CVD) risk factors such as hypertension, coronary heart disease, dyslipidemia, atrial fibrillation, and depression. Despite these overwhelming findings, large amounts of evidence support the presence of an "obesity paradox," where obese patients with CVD have a better prognosis than do lean or normal weight in patients with CVD...
November 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28919124/foreword
#13
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28870377/cardiac-imaging-in-the-diagnosis-of-coronary-artery-disease
#14
Ashvarya Mangla, Estefania Oliveros, Kim Allan Williams, Dinesh K Kalra
Coronary artery disease (CAD) continues to be a leading cause of morbidity and mortality worldwide. Although invasive coronary angiography has previously been the gold standard in establishing the diagnosis of CAD, there is a growing shift to more appropriately use the cardiac catheterization laboratory to perform interventional procedures once a diagnosis of CAD has been established by noninvasive imaging modalities rather than using it primarily as a diagnostic facility to confirm or refute CAD. With ongoing technological advancements, noninvasive imaging plays a pre-eminent role in not only diagnosing CAD but also informing the choice of appropriate therapies, establishing prognosis, all while containing costs and providing value-based care...
October 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28818325/foreword
#15
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28764841/non-st-elevation-acute-coronary-syndromes-a-comprehensive-review
#16
REVIEW
Tamunoinemi Bob-Manuel, Ikechuckwu Ifedili, Guy Reed, Uzoma N Ibebuogu, Rami N Khouzam
Non-ST elevation-acute coronary syndrome (NSTE-ACS) includes NSTE myocardial infarction and unstable angina. This patient population forms approximately two-thirds of all hospital admissions for ACS in the United States each year and is associated with an in-hospital mortality of 5%. NSTE-ACS is primarily due to an acute change in the supply and demand balance of coronary perfusion and myocardial oxygen consumption, because of the significant coronary artery obstruction presenting as plaque rupture or erosion...
September 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28764840/foreword
#17
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29032851/foreword
#18
(no author information available yet)
No abstract text is available yet for this article.
August 18, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28709475/evolution-of-american-academic-medicine-a-view-of-its-contributions-to-world-medicine-and-reflections-influenced-by-personal-role-models
#19
Edward D Frohlich
The changes in American academic medicine in the last 6 decades has been a success. During these years, I participated in this development through patients care, research, editorship of major Journals and as a member of governing boards of several professional organizations. This discussion will describe some of the developments of medicine and will recount my own professional career and my mentors who help me to achieve my goals.
August 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28709474/foreword
#20
Hector O Ventura
No abstract text is available yet for this article.
August 2017: Current Problems in Cardiology
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