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Nuklearmedizin. Nuclear Medicine

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https://www.readbyqxmd.com/read/29871014/nachrichten-der-deutschen-gesellschaft-f%C3%A3-r-nuklearmedizin
#1
(no author information available yet)
No abstract text is available yet for this article.
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29871013/nodular-fasciitis-mimicking-malignant-soft-tissue-tumor-in-an-infant-with-18f-fdg-pet-ct-findings-a-case-report
#2
Byung Wook Choi, Hae Won Kim, Jae Cheon Jeon, Sungmin Kang
No abstract text is available yet for this article.
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29871012/-combined-internal-external-radiotherapy-ciert-in-a-cell-model
#3
Liane Oehme, Thomas Bartzsch, Ute Maucksch, Robert Freudenberg, Gerd Wunderlich, Jörg Kotzerke
AIM: Combined internal-external radiotherapy (CIERT) requires a unified assessment of biologic radiation effects in addition to the total dose. The concept of biological effective dose (BED) was evaluated in a cell model. METHODS: The thyroid NIS-positive cell line FRTL-5 was irradiated with X-ray and the radiotracer Tc-99m pertechnetate either alone or in combination. The cellular uptake of the radionuclide during the incubation time of 24 h was controlled by the presence or absence of perchlorate...
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29871011/comparison-of-68ga-and-fluorescence-labeled-microspheres-for-measurement-of-relative-pulmonary-perfusion-in-anesthetized-pigs
#4
Anja Braune, Martin Scharffenberg, Anne Naumann, Thomas Bluth, Marcelo Gama de Abreu, Jörg Kotzerke
AIM: We compared 68 Gallium (68 Ga)- and fluorescence-labeled microspheres for measurement of pulmonary perfusion distribution in anesthetized pigs without lung injury. METHODS: In two mechanically ventilated pigs, the distribution of pulmonary perfusion was marked in vivo with 68 Ga- and fluorescence-labeled microspheres in supine and prone position. After each injection, the distribution of 68 Ga-labeled microspheres was measured in vivo with positron emission tomography/ computed tomography (PET/CT) in the position in which microspheres were injected and vice versa...
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29871010/diagnostic-and-prognostic-value-of-additional-spect-ct-in-sentinel-lymph-node-mapping-in-breast-cancer-patients
#5
Susanne Stanzel, Birgit Pernthaler, Thomas Schwarz, Vesna Bjelic-Radisic, Stefan Kerschbaumer, Reingard M Aigner
THE AIM: of the study was to demonstrate the diagnostic and prognostic value of SPECT/CT in sentinel lymph node mapping (SLNM) in patients with invasive breast cancer. METHODS: 114 patients with invasive breast cancer with clinically negative lymph nodes were included in this retrospective study as they were referred for SLNM with 99m Tc-nanocolloid. Planar image acquisition was accomplished in a one-day or two-day protocol depending on the schedule of the surgical procedure...
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29871009/-lung-scintigraphy
#6
Carl Schümichen, Matthias Schmidt, Thomas Krause
The S1 guideline for lung scintigraphy has been updated and extended in order to emphasize the advantages oft the method in detecting acute pulmonary embolism (PE) in the periphery oft the lung (subsegmental PE), in underlying subacute and chronic pulmonary disorders, as well as in detecting chronic LE (CTEPH). Method of choice is ventilation / perfusion (V/P) SPECT or V/P SPECT/CT with even higher specificity. Because of its high sensitivity, a threshold (V/P mismatch in at least one segment or two subsegments) is introduced to avoid overtreatment...
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29871008/-psma-pet-ct-has-to-be-performed-in-every-patient-with-biochemical-recurrence-following-radical-prostatectomy-for-early-tumor-detection
#7
Jörg Kotzerke, Dirk Böhmer, Thorsten Schlomm, Thomas Maurer, Ambros J Beer, Heinz Schmidberger
The debate refers the known evidence for PSMA-PET/CT in biochemical recurrence of prostate cancer and consider carefully interdisciplinary in which situation which patient needs imaging to choose the adequate therapeutic option. General aspects for the care of cancer patients are taken into consideration.
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29871007/nuklearmedizin-in-deutschland-2018
#8
Bernd Joachim Krause
No abstract text is available yet for this article.
June 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29590679/nachrichten-der-deutschen-gesellschaft-f%C3%A3-r-nuklearmedizin
#9
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29590678/56-jahrestagung-der-deutschen-gesellschaft-f%C3%A3-r-nuklearme
#10
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29590677/successful-handling-of-an-accidental-extravasation-of-177lu-psma-617-in-the-treatment-of-advanced-prostate-cancer
#11
Michael Jüptner, Maaz Zuhayra, Isong Assam, Ulf Lützen
No abstract text is available yet for this article.
April 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29590676/radiotoxicity-of-alpha-particles-versus-high-and-low-energy-electrons-in-hypoxic-cancer-cells
#12
Ute Maucksch, Roswitha Runge, Liane Oehme, Jörg Kotzerke, Robert Freudenberg
PURPOSE: Hypoxic regions of tumors are less sensitive to radio- and chemotherapy, leading to poor prognosis of patients. One option to overcome the radioresistance is the irradiation of hypoxic tumors with high linear energy transfer (LET) α- or Auger electronemitters assuming their radiotoxicity would be less dependent on the cellular oxygenation status. Therefore, the aim of the present study was to determine whether irradiation with the intracellularly distributed Auger electron/γ-emitter 99m Tc using the tracer [99m Tc]TcHMPAO is a promising therapeutic option for the treatment of hypoxic tumor cells...
April 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29590675/influence-of-scan-time-point-and-volume-of-intravenous-contrast-administration-on-blood-pool-and-liver-suvmax-and-suvmean-in-18f-fdg-pet-ct
#13
Matthias Schoen, Timm Braun, Panagiota Manava, Sigrid Ludwigs, Michael Lell
AIM: To investigate the influence of scan time point and volume of intravenous contrast material in 18F-FDG PET/CT on maximum and mean standardized uptake values (SUVmax /mean ) in bloodpool and liver. METHODS: In 120 patients scheduled for routine whole-body 18F-FDG PET/CT the maximum and mean standardized uptake values (SUVmax /SUVmean ) in the liver and blood pool were measured after varying scan time-point (delay 0 s-140 s post injectionem) and volume of contrast material (CM; 0 ml, 80 ml, 100 ml of 300 mg/ml of Iodine)...
April 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29590674/-influence-of-glucocorticoid-therapy-on-intratherapeutic-biodistribution-of-131i-radioiodine-therapy-in-graves-disease
#14
Jörg Halstenberg, Wolfgang Tilman Kranert, Hüdayi Korkusuz, Amelie Mayer, Hanns Ackermann, Frank Grünwald, Christian Happel
AIM: Radioiodine therapy (RIT) is an important therapeutic method in the definitive treatment of Graves' disease (GD). However, RIT may trigger development of Graves' ophthalmopathy (GO) or exacerbate a pre-existing GO. Therefore, the procedure recommendation of the DGN (German Society of Nuclear Medicine) for RIT of benign thyroid diseases recommends an additional glucocorticoid therapy for patients with pre-existing GO. Aim of this study was to analyze the influence of a protective glucocorticoid therapy on 131 I biokinetics during RIT of patients with GD...
April 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29590673/willkommen-im-bremen
#15
Winfried Brenner
No abstract text is available yet for this article.
April 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29536500/international-consensus-radiochemistry-nomenclature-guidelines
#16
Heinz H Coenen, Antony D Gee, Michael Adam, Gunnar Antoni, Cathy S Cutler, Yasuhisa Fujibayashi, Jae Min Jeong, Robert H Mach, Thomas L Mindt, Victor W Pike, Albert D Windhorst
No abstract text is available yet for this article.
February 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29536499/i-123-mibg-scintigraphy-in-patients-with-neuroblastoma
#17
Julian M M Rogasch, Holger Amthauer, Christian Furth, Patrick Hundsdoerfer, Florian Wedel, Imke Schatka
AIM: According to German guidelines, I-123-MIBG scintigraphy in neuroblastoma (NB) is preferably performed as early (about 4 h p.i.) and late (24 h p.i.) planar imaging and single- photon emission computed tomography (SPECT) or SPECT/CT 24 h p.i. This study evaluated if the work-up could be reduced to a single timepoint. METHODS: Retrospective analysis of 37 examinations in 26 patients (f:8; m:18; age, 0.5-23.5a) with NB (initial, 15; restaging, 22). All 74 (early + late) pairs of ventral/dorsal planar whole-body images were reviewed by 3 independent readers in random order blinded to clinical data (1, certainly physiological; 2, likely physiological; 3, likely malignant; 4, certainly malignant)...
February 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29536498/volume-perfusion-ratio-from-lung-spect-ct
#18
Wolfgang Michael Schaefer, Daniela Knollmann, Jerome Avondo, Andreas Meyer
AIM: In pulmonary emphysema lung volume reduction procedures (LVRP) can optimize respiratory pump function. Identification of the most affected lobe can be reached using relative lobar volume (relVol) from CT, but this approach disregards the corresponding lobar perfusion. The aim of the study was therefore to establish a new parameter combining relVol from CT and relative perfusion (relPerf) from perfusion SPECT as a single parameter (volume/perfusion ratio (VPR)) to optimize the identification procedure...
February 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29536497/-18f-fdg-pet-ct-for-assessing-inguinal-lymph-nodes-in-patients-with-penile-cancer-correlation-with-histopathology-after-inguinal-lymphadenectomy
#19
Desiree L Dräger, Martin Heuschkel, Chris Protzel, Andreas Erbersdobler, Bernd J Krause, Oliver W Hakenberg, Sarah M Schwarzenböck
AIM: Accurate staging of penile cancer requires invasive methods such as sentinel node biopsy or lymphadenectomy (LAD). We assessed the value of [18 F]FDG PET/CT for non-invasive nodal staging in penile cancer (PC) patients before inguinal LAD. PATIENTS AND METHODS: 41 consecutive patients with PC (stage pT1 or higher, cN0) received [18 F]FDG PET/CT before undergoing bilateral modified or radical inguinal staging LAD. Lymph nodes with a visually increased [18 F]FDG uptake were classified as suspicious of lymph node metastases (LNM)...
February 2018: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29536496/relevant-tumor-sink-effect-in-prostate-cancer-patients-receiving-177lu-psma-617-radioligand-therapy
#20
Christian Filss, Alexander Heinzel, Berthold Miiller, Andreas T J Vogg, Karl-Josef Langen, Felix M Mottaghy
AIM: In metastatic prostate cancer patients PSMA targeting radioligands have gained significant impact as theranostic probes. In this study a correlation between total tumor volume (TTV) and measured kidney dose as well as salivary glands (SG) uptake in 177 Lu-PSMA-617 therapy was evaluated. METHODS: Eleven consecutive prostate cancer patients receiving a first cylcle of 177 Lu-PSMA-617 (administered activity of approximately 6GBq) were included. The 68 Ga-PSMA-11 PET/CT scan previous to therapy was used to determine TTV and SG uptake (glandulae submandibularis) employing PMOD version 3...
February 2018: Nuklearmedizin. Nuclear Medicine
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