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Clinical and Experimental Dermatology

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https://www.readbyqxmd.com/read/28649780/therapeutic-efficacy-and-safety-of-oral-tranexamic-acid-and-that-of-tranexamic-acid-local-infiltration-with-microinjections-in-patients-with-melasma-a-comparative-study
#1
R Sharma, V K Mahajan, K S Mehta, P S Chauhan, R Rawat, T N Shiny
BACKGROUND: Tranexamic acid (TXA) has been used orally, intravenously, topically and intradermally (microinjection, microneedling) for treating melasma. However, the comparative efficacy of these different routes of administration remains underevaluated. AIM: To ascertain the comparative efficacy of different routes of administration of TXA. METHODS: In total, 100 consecutive patients with melasma (8 men, 92 women, age range 18-55 years) were randomly assigned to one of two groups comprising 50 patients each...
June 25, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28649778/granuloma-faciale-associated-with-igg4-related-disease
#2
LETTER
N López-Navarro, E Gallego-Dominguez, A Vargas-Nevado, R Castillo-Muñoz, E Herrera
No abstract text is available yet for this article.
June 25, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28649751/long-term-management-of-chronic-spontaneous-urticaria-with-omalizumab
#3
M Pinto Gouveia, A Gameiro, A Pinho, M Gonçalo
BACKGROUND: Clinical trials have shown the efficacy of omalizumabs efficacy in refractory chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU), but real-life management strategies are lacking. AIM: To assess the long-term efficacy and safety of omalizumab, and to identify predictive factors and optimum dosage regimens. METHODS: This was a prospective study of 13 patients (11 women, 2 men) with severe CSU [weekly urticaria activity score (UAS7) > 28] resistant to anti-H1 antihistamines...
June 25, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28649738/adjuvant-therapy-with-low-dose-interferon-beta-for-stage-ii-and-iii-melanoma-results-of-a-retrospective-analysis
#4
T Yanagi, H Hata, E Homma, S Kitamura, K Imafuku, H Shimizu
Interferon (IFN)-alfa as an adjuvant therapy has been found to improve relapse-free survival in patients with malignant melanoma (MM). However, the efficacy of IFN-beta has not been studied in detail. This study evaluated the contribution of adjuvant IFN-beta therapy to improvements in the prognosis of patients with MM. We reviewed 63 patients with resected stage II/III primary MM at our institution. Of these, 36 had been treated with IFN-beta adjuvant therapy (subcutaneous injection, 3 × 10(6) IU/day, 10 days), while 27 patients had undergone observation alone...
June 25, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28639716/expression-of-the-autoantigen-trim33-tif1%C3%AE-in-skin-and-muscle-of-patients-with-dermatomyositis-is-upregulated-together-with-markers-of-cellular-stress
#5
B Scholtissek, S Ferring-Schmitt, J Maier, J Wenzel
Dermatomyositis (DM) is an autoimmune disorder associated with a dysregulation of immune homeostasis of both the innate and adaptive immune system. Earlier data suggested that these two arms of the immune system interconnect in DM. In the current study, we analysed the association of autoantigen expression [adaptive system components: Mi2, transcriptional intermediary factor (TIF)1γ, small ubiquitin-like modifier 1 activating enzyme subunit (SAE)1, melanoma differentiation-associated protein (MDA)5] with markers of cellular stress (innate system components: MxA, p53) in skin and muscle (immunohistology and gene expression data, respectively)...
June 22, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28639715/refractory-chronic-spontaneous-urticaria-associated-with-cd4-lymphocytopenia-in-a-patient-with-thymoma
#6
J Wu, L M Zhang, T Xiao, H D Chen
No abstract text is available yet for this article.
June 22, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28639713/rosacea-in-black-south-africans-with-skin-phototypes-v-and-vi
#7
N C Dlova, A Mosam
Rosacea is a chronic facial dermatosis considered to affect primarily white patients with light phototype skin, and is poorly documented in black patients. The aim of this study was to document the clinical features of rosacea in patients with phototypes V and VI. An 8-year retrospective chart review of patients with a clinical and histological diagnosis of rosacea or acne rosacea was undertaken. Of 6700 patients, 15 (0.2%) had rosacea. All were of African descent with skin phototype V or VI. Mean age was 47 years, and female : male ratio was 14 : 1...
June 22, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28639709/vesiculobullous-variant-of-erythema-elevatum-diutinum
#8
L Ossorio-García, D Jiménez-Gallo, C Arjona-Aguilera, M Salamanca-Sánchez, M Linares-Barrios
The vesiculobullous variant of erythema elevatum diutinum (EED) is a very rare variant of EED. We describe a 16-year-old boy who presented with symmetrical nodular lesions accompanied by vesicles on the dorsa of his hands. Biopsy findings were consistent with EED. The histopathological presence of IgA and neutrophils in the vesicles indicates that the joint action of both is responsible for formation of these subepidermic vesicles. We hypothesize that absence of human leucocyte antigen related to dermatitis herpetiformis (DH) in our patient might have influenced the location and distribution of the lesions, so that they were not typical of DH...
June 22, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28639343/first-case-of-anaphylaxis-after-botulinum-toxin-type-a-injection
#9
I J Moon, S E Chang, S D Kim
Botulinum toxin type A (BTA) (also known as onabotulinum toxin A) injection is widely used in the field of cosmetic dermatology. Although a few adverse events related to intramuscular BTA injection have been reported, no life-threatening adverse reaction has been documented to date. We report a case of anaphylaxis induced by intramuscular BTA injection into the masseter muscles of a 35-year-old woman. She had previously received injections of the identical BTA product into the same muscles without incident...
June 21, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28636260/lichenoid-keratosis-is-frequently-misdiagnosed-as-basal-cell-carcinoma
#10
D Maor, C Ondhia, L L Yu, J J Chan
Lichenoid keratosis (LK), also known as benign lichenoid keratosis or lichen planus-like keratosis, is a solitary, pink to red-brown scaly plaque representing a host immunological response to a variety of precursor lesions. LK is often misdiagnosed as a dermatological malignancy owing to its clinical resemblance to basal cell carcinoma (BCC) or Bowen disease. We performed a retrospective analysis of the pathology records of a series of LK lesions with reference to the demographic features and accuracy of clinical diagnosis...
June 21, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28636090/chronic-inflammatory-acantholytic-dermatosis-a-previously-under-recognized-or-emerging-variant-of-grover-disease
#11
LETTER
J L C Wong, A Bakshi, L C Stewart, A Al-Sharqi
No abstract text is available yet for this article.
June 21, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28636073/chanarin-dorfman-syndrome
#12
B Demir, A Sen, L Bilik, U Deveci, I H Ozercan, D Cicek, Y Dogan
No abstract text is available yet for this article.
June 21, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28621002/real-world-single-centre-experience-of-apremilast-for-the-treatment-of-moderate-to-severe-psoriasis
#13
LETTER
T H Wong, S Sinclair, B Smith, C Fraser, C A Morton
No abstract text is available yet for this article.
June 16, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28616880/imiquimod-induced-cutaneous-lupus-erythematosus-with-antinuclear-antibodies-showing-a-homogenous-pattern
#14
LETTER
D Jiménez-Gallo, B J F Brandão, C Arjona-Aguilera, J M Báez-Perea, M Linares-Barrios
No abstract text is available yet for this article.
June 14, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28616878/lichen-striatus-following-yellow-fever-vaccination-in-an-adult-woman
#15
M Karouni, M Kurban, O Abbas
No abstract text is available yet for this article.
June 14, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28614617/urticaria-pigmentosa-with-concomitant-polycythaemia-vera-in-a-3-year-old-boy
#16
B E K Guevara, V P Guillano, J F Dayrit
No abstract text is available yet for this article.
June 14, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28614598/pulmonary-adenocarcinoma-diagnosed-by-incisional-skin-metastasis-in-an-old-scar-from-a-non-neoplastic-surgery
#17
B R Ferreira, M M Brites, J C Cardoso, J P Reis
No abstract text is available yet for this article.
June 14, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28598021/onset-of-kaposi-sarcoma-and-merkel-cell-carcinoma-during-low-dose-steroid-therapy-for-rheumatic-polymyalgia
#18
L Brambilla, L Esposito, G Nazzaro, A Tourlaki
No abstract text is available yet for this article.
June 9, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28598008/a-persistent-umbilical-nodule
#19
A Ramoutar, S El Sheikh, A Aslam
No abstract text is available yet for this article.
June 9, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28597997/an-under-recognized-life-threatening-complication-of-atopic-dermatitis
#20
C Pagliarello, S Scrivani, G Fabrizi, C Feliciani, S Di Nuzzo
No abstract text is available yet for this article.
June 9, 2017: Clinical and Experimental Dermatology
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