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Clinical and Experimental Dermatology

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https://www.readbyqxmd.com/read/28211143/alitretinoin-treatment-in-mycosis-fungoides-with-cd30-positive-large-cell-transformation
#1
LETTER
J Park, O Kwon, K Park, H Chung
No abstract text is available yet for this article.
February 16, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28211129/detection-of-serpinb7-mutation-can-distinguish-nagashima-type-palmoplantar-keratoderma-from-other-keratodermas-with-palmoplantar-lesions
#2
LETTER
T Hashimoto, K Teye, S Numata, Y Suga, T Hamada, N Ishii
No abstract text is available yet for this article.
February 16, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28211089/icariin-promotes-mouse-hair-follicle-growth-by-increasing-insulin-like-growth-factor-1-expression-in-dermal-papillary-cells
#3
Y-S Su, Z-X Fan, S-E Xiao, B-J Lin, Y Miao, Z-Q Hu, H Liu
BACKGROUND: Icariin is a major flavonoid isolated from Epimedium spp. leaves (Epimedium Herba), and has multiple pharmacological functions, including anti-angiogenesis, anti-oxidant, anti-inflammatory and immunoprotective effects. AIM: To investigate whether icariin can stimulate growth of hair follicles in mice and the underlying mechanism. METHODS: In vitro, the effect of icariin on hair growth was assessed by using a vibrissae hair follicle (VHF) organ-culture model...
February 16, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28211077/severe-bullous-pemphigoid-associated-with-pembrolizumab-therapy-for-metastatic-melanoma-with-complete-regression
#4
O Rofe, G Bar-Sela, Z Keidar, T Sezin, C D Sadik, R Bergman
Bullous pemphigoid (BP) is considered to be a humorally mediated autoimmune disease, but autoreactive T-cells and T-regulatory cells (Tregs) have also been implicated in this disease. Tregs and the programmed death-1 (PD-1) : programmed death ligand (PD-L) pathway are both critical in terminating immune response, and elimination of either can result in breakdown of tolerance and development of autoimmunity. We report a patient with metastatic malignant melanoma (MM), who underwent pembrolizumab (anti-PD-1) therapy following unsuccessful treatment with ipilimumab [anti-cytotoxic T-lymphocyte-associated protein (CTLA)-4]...
February 16, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28194809/prodromal-symptoms-in-hidradenitis-suppurativa
#5
H C Ring, P Theut Riis, K Zarchi, I M Miller, D M Saunte, G B Jemec
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease, which presents as recurrent nodules and sinus tracts (tunnels) with subsequent scarring, predominantly involving the intertriginous regions. Although prodromal symptoms (i.e. various symptoms preceding the eruption of the HS lesions) are often mentioned, there have been no formal investigations into this aspect. Insight into prodromal symptoms may enable patients with HS or dermatologists in choosing a more targeted treatment at a much earlier stage, potentially increasing treatment efficacy and quality of life...
February 14, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28194816/verrucous-discoid-lupus-erythematosus-in-a-child
#6
F Topaloglu Demir, F Deniz, Y Ozben, I Kivanc Altunay
No abstract text is available yet for this article.
February 13, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28194815/peristomal-psoriasis
#7
C Marshall, S Woodmansey, C C Lyon
BACKGROUND: Psoriasis is a common skin condition, affecting 1.3-2.2% of the population. The prevalence of psoriasis has previously been reported as 11.2% in patients with Crohn disease (CD) and 5.7% in patients with ulcerative colitis. AIM: To assess the prevalence of psoriasis around stoma sites and identify the most effective treatment. METHODS: A departmental database of all patients attendings stoma clinic was accessed between 1 May 2003 and 15 October 2015...
February 13, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28188648/pilot-study-to-evaluate-a-plasma-device-for-the-treatment-of-onychomycosis
#8
S R Lipner, G Friedman, R K Scher
Onychomycosis is a fungal infection of the nail unit, and is the most common of the nail disorders. Current therapies for onychomycosis have less than ideal efficacy and have the potential for adverse effects. As previous studies have shown that nonthermal plasma inhibits the in vitro growth of Trichophyton rubrum, we conducted a pilot study on 19 participants with toenail onychomycosis. The primary endpoint was safety of the device, and secondary outcome measures were clinical efficacy and mycological cure...
February 11, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28188645/fingolimod-and-melanoma-risk-is-there-sufficient-evidence
#9
LETTER
A Filoni, L Lospalluti, G Giudice, D Bonamonte, M Vestita
No abstract text is available yet for this article.
February 11, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28111789/treatment-of-adult-diffuse-pityriasis-lichenoides-chronica-with-narrowband-ultraviolet-b-experience-and-literature-review
#10
M Fernández-Guarino, S Aboin-Gonzalez, C Ciudad Blanco, D Velázquez Tarjuelo, P Lázaro Ochayta
Pityriasis lichenoides chronica (PLC) is an infrequent dermatosis of unknown aetiology, wholse evolution and response to treatment differs between children and adults. When PLC is recalcitrant or unresponsive to topical treatment, phototherapy is one of the main treatments used. We carried out a prospective study of adult diffuse PLC treated with narrowband ultraviolet B (NB-UVB). We treated eight patients whose disease showed no response to topical therapy, and obtained a complete response rate of 88% in a mean of 23 sessions (cumulative dose 16...
January 23, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28111786/enlarging-plaques-and-nodules-on-the-face-and-legs
#11
A Flynn, C Kiely, A M Tobin, M Jeffers, M Connolly
No abstract text is available yet for this article.
January 23, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28111784/myaesthenia-gravis-exacerbation-caused-by-axillary-injection-of-botulinum-toxin-a-for-treatment-of-hyperhidrosis
#12
S El-Heis, G Burke, W Gibb, M R Ardern-Jones
No abstract text is available yet for this article.
January 23, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28084616/piperacillin-tazobactam-induced-linear-iga-bullous-dermatosis-presenting-clinically-as-stevens-johnson-syndrome-toxic-epidermal-necrolysis-overlap
#13
N R Adler, C A McLean, A K Aung, M S Y Goh
Linear IgA bullous dermatosis (LABD) is a subepidermal autoimmune bullous disease characterized by linear IgA deposition at the basement membrane zone, which is visualized by direct immunofluorescence. Patients with LABD typically present with widespread vesicles and bullae; however, this is not necessarily the case, as the clinical presentation of this disease is heterogeneous. LABD clinically presenting as Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) is an infrequent, yet well-described phenomenon...
January 13, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28071814/genital-porokeratosis-with-amyloid-deposition-mimicking-extramammary-paget-disease
#14
LETTER
T Mori, T Yamamoto
No abstract text is available yet for this article.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28070920/unusual-skin-changes-on-the-neck
#15
A D Lock, F Deroide, M H A Rustin, V Jolliffe
No abstract text is available yet for this article.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28070901/a-case-of-blue-naevus-of-the-mucocutaneous-junction-of-the-lower-eyelid-margin-associated-with-acquired-bilateral-naevus-of-ota-like-macule
#16
LETTER
T Nako, T Hoashi, A Kanzaki, N Serizawa, Y Funasaka, H Saeki
No abstract text is available yet for this article.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28070898/clearance-of-recalcitrant-warts-in-a-patient-with-idiopathic-immune-deficiency-following-administration-of-the-quadrivalent-human-papillomavirus-vaccine
#17
S P Smith, H E Baxendale, J C Sterling
Human papillomavirus (HPV)-induced cutaneous warts are potentially serious and debilitating. In immunosuppressed patients, these warts may be resistant to standard therapies. We report a case of a young patient with a primary immune deficiency whose recalcitrant cutaneous warts regressed completely following administration of a quadrivalent HPV vaccine.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28054376/toll-like-receptor-tlr-7-expression-in-mycosis-fungoides-and-psoriasis-a-case-control-study
#18
A M El Tawdy, I M Amin, R M Abdel Hay, A S Hassan, Z S Gad, L A Rashed
BACKGROUND: Toll-like receptors (TLRs) have been implicated in various dermatological diseases. TLR agonists have the capacity to potently activate the innate immune cells of patients with advanced, refractory, cutaneous T-cell lymphoma (CTCL). AIM: To detect TLR7 gene expression in mycosis fungoides (MF) (a neoplastic skin condition) and to compare it with psoriasis (an inflammatory skin condition) in an attempt to clarify the pathogenic role played by TLR7 in both conditions...
January 5, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28054370/unilateral-blue-rubber-bleb-naevus-syndrome-with-chiari-malformation
#19
LETTER
F Topaloglu Demir, F Deniz, A Mesrur Halefoglu, I Kivanc Altunay, K Esen Salman
No abstract text is available yet for this article.
January 5, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052512/innate-immunity-in-cutaneous-melanoma
#20
REVIEW
C Mignogna, E Scali, C Camastra, I Presta, P Zeppa, T Barni, G Donato, U Bottoni, A Di Vito
The skin immune system is composed of a vast network of immune cells, including lymphocytes, macrophages, neutrophils, dendritic cells and Langerhans cells, which not only are involved in inflammatory responses but also contribute to homeostatic function and may participate in the various steps of carcinogenesis. Many studies support the notion that innate immunity has a key role in the development, growth and prognosis of cutaneous malignant melanoma (MM), through the release of pro- and/or anti-inflammatory cytokines and tumour growth factors...
January 4, 2017: Clinical and Experimental Dermatology
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