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Clinical and Experimental Dermatology

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https://www.readbyqxmd.com/read/28084616/piperacillin-tazobactam-induced-linear-iga-bullous-dermatosis-presenting-clinically-as-stevens-johnson-syndrome-toxic-epidermal-necrolysis-overlap
#1
N R Adler, C A McLean, A K Aung, M S Y Goh
Linear IgA bullous dermatosis (LABD) is a subepidermal autoimmune bullous disease characterized by linear IgA deposition at the basement membrane zone, which is visualized by direct immunofluorescence. Patients with LABD typically present with widespread vesicles and bullae; however, this is not necessarily the case, as the clinical presentation of this disease is heterogeneous. LABD clinically presenting as Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) is an infrequent, yet well-described phenomenon...
January 13, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28071814/genital-porokeratosis-with-amyloid-deposition-mimicking-extramammary-paget-disease
#2
LETTER
T Mori, T Yamamoto
No abstract text is available yet for this article.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28070920/unusual-skin-changes-on-the-neck
#3
A D Lock, F Deroide, M H A Rustin, V Jolliffe
No abstract text is available yet for this article.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28070901/a-case-of-blue-naevus-of-the-mucocutaneous-junction-of-the-lower-eyelid-margin-associated-with-acquired-bilateral-naevus-of-ota-like-macule
#4
LETTER
T Nako, T Hoashi, A Kanzaki, N Serizawa, Y Funasaka, H Saeki
No abstract text is available yet for this article.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28070898/clearance-of-recalcitrant-warts-in-a-patient-with-idiopathic-immune-deficiency-following-administration-of-the-quadrivalent-human-papillomavirus-vaccine
#5
S P Smith, H E Baxendale, J C Sterling
Human papillomavirus (HPV)-induced cutaneous warts are potentially serious and debilitating. In immunosuppressed patients, these warts may be resistant to standard therapies. We report a case of a young patient with a primary immune deficiency whose recalcitrant cutaneous warts regressed completely following administration of a quadrivalent HPV vaccine.
January 10, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28054376/toll-like-receptor-tlr-7-expression-in-mycosis-fungoides-and-psoriasis-a-case-control-study
#6
A M El Tawdy, I M Amin, R M Abdel Hay, A S Hassan, Z S Gad, L A Rashed
BACKGROUND: Toll-like receptors (TLRs) have been implicated in various dermatological diseases. TLR agonists have the capacity to potently activate the innate immune cells of patients with advanced, refractory, cutaneous T-cell lymphoma (CTCL). AIM: To detect TLR7 gene expression in mycosis fungoides (MF) (a neoplastic skin condition) and to compare it with psoriasis (an inflammatory skin condition) in an attempt to clarify the pathogenic role played by TLR7 in both conditions...
January 5, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28054370/unilateral-blue-rubber-bleb-naevus-syndrome-with-chiari-malformation
#7
LETTER
F Topaloglu Demir, F Deniz, A Mesrur Halefoglu, I Kivanc Altunay, K Esen Salman
No abstract text is available yet for this article.
January 5, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052512/innate-immunity-in-cutaneous-melanoma
#8
REVIEW
C Mignogna, E Scali, C Camastra, I Presta, P Zeppa, T Barni, G Donato, U Bottoni, A Di Vito
The skin immune system is composed of a vast network of immune cells, including lymphocytes, macrophages, neutrophils, dendritic cells and Langerhans cells, which not only are involved in inflammatory responses but also contribute to homeostatic function and may participate in the various steps of carcinogenesis. Many studies support the notion that innate immunity has a key role in the development, growth and prognosis of cutaneous malignant melanoma (MM), through the release of pro- and/or anti-inflammatory cytokines and tumour growth factors...
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052437/dabigatran-in-the-management-of-livedoid-vasculopathy
#9
T Sawada, M Suehiro
No abstract text is available yet for this article.
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052374/use-of-nicotinamide-in-dermatology
#10
REVIEW
E Forbat, F Al-Niaimi, F R Ali
Nicotinamide (niacinamide) is the water-soluble, amide form of vitamin B3. We review the evidence underlying the use of nicotinamide for various dermatological indications, including nonmelanoma cancer prophylaxis, blistering disorders, acne vulgaris and cosmetic indications, and speculate upon its future role in dermatological practice.
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052372/segmental-lichen-aureus-in-infancy
#11
LETTER
Y Saito, Y Shimomura, M Orime, N Kariya, R Abe
No abstract text is available yet for this article.
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052370/acantholytic-dermatosis-of-the-vagina-the-diagnostic-challenge-of-acantholytic-disease-in-the-genital-region
#12
J Kentley, R Cerio, M Khorshid, K Gibbon
We report the case of a 24-year-old woman with an 8-month history of deep pelvic pain and postcoital bleeding. Examination revealed desquamation of the vaginal epithelium with tender fissured plaques in the vagina, initially thought to be vaginal intraepithelial neoplasia. Histology showed squamous mucosa with suprabasal acantholysis and hyperkeratosis, and no evidence of viral infection, dysplasia or malignancy. These findings were consistent with acantholytic dermatosis (AD), a rare lesion that resembles Hailey-Hailey and Darier disease histopathologically, but can be distinguished on a clinical basis...
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052369/development-of-abdominal-wall-endometriosis-in-a-region-distant-from-a-caesarean-section-scar
#13
LETTER
S Egami, Y Kumagai, T Yokoyama, M Sugiura
No abstract text is available yet for this article.
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052368/synthesis-and-activity-of-the-salicylic-acid-ester-of-bakuchiol-in-psoriasis-surrogate-keratinocytes-and-skin-substitutes
#14
S Ma, K Gobis, W R Swindell, R Chaudhuri, R Bojanowski, K Bojanowski
BACKGROUND: Topical retinoids are effective in retarding skin ageing and restoring homeostasis in skin conditions such as psoriasis. However their adverse effects (AEs), which include irritation (retinoid dermatitis), photosensitivity and teratogenicity, limit their use and patient compliance. Development of retinoid analogues with minimal AEs would allow a broader and more compliant use. AIM: To synthesise a novel molecule, bakuchiol salicylate (bakusylan), with a modulatory gene expression profile similar to retinoids, using as reference three prescription retinoids: tretinoin, tazarotene and adapalene...
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052367/morphoea-with-prominent-plasma-cell-endoneuritis
#15
M Singh, N Farquharson, C Owen, A J Howat, S Singh, N Francis, E Calonje
Morphoea (localized scleroderma) is a cutaneous inflammatory condition characterized by the development of indurated and discoloured plaques. The histological features of morphoea typically include a superficial and deep perivascular and periadnexal chronic inflammatory infiltrate associated with variable degrees of dermal and/or subcutaneous sclerosis. The infiltrate is typically composed of lymphocytes, macrophages and conspicuous plasma cells. The early stages of morphoea may have a very prominent inflammatory infiltrate associated with subtle sclerosis...
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052364/hypothyroidism-associated-with-nivolumab-treatment-of-unresectable-malignant-melanoma
#16
LETTER
K Imafuku, K Yoshino, K Yamaguchi, S Tsuboi, K Ohara, H Hata
No abstract text is available yet for this article.
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052362/dermal-hyperneury-a-rare-but-increasingly-recognized-entity
#17
LETTER
N Watson, R Gardner, C Moyes, E Calonje, A MacDonald
No abstract text is available yet for this article.
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052359/diffuse-angiomatosis-with-severe-facial-disfigurement
#18
LETTER
T Gambichler, S Ziarna, A Deutsch, A Janus, M Stücker, M Doerler
No abstract text is available yet for this article.
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28052358/use-of-optical-coherence-tomography-for-the-diagnosis-of-preclinical-lesions-of-circumscribed-palmar-hypokeratosis
#19
G Abignano, A Kapadia, G Lettieri, M Goodfield, P Emery, D McGonagle, F Del Galdo, J Mikeljevic
Circumscribed hypokeratosis of palms and soles is a rare dermatosis, usually affecting women. Diagnosis is mainly based on the clinical characteristics, including the clinical appearance and anatomical site of the skin lesions and on the demographic features of the affected patients, usually middle-aged to elderly women. Skin biopsy may be performed to confirm clinical diagnosis. Optical coherence tomography (OCT) is a technique that has been undergone substantial development in dermatology in recent years, and its use in clinical practice has been growing progressively...
January 4, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28044372/psoriasis-and-metabolic-syndrome-in-children-current-data
#20
A Pietrzak, E Grywalska, M Walankiewicz, T Lotti, J Roliński, W Myśliński, P Chabros, D Piekarska-Myślińska, K Reich
BACKGROUND: The prevalence of cardiovascular and metabolic disorders in paediatric patients with psoriasis is not well established. AIM: To conduct a meta-analysis of previously published studies dealing with the occurrence of metabolic disorders in children with psoriasis. METHODS: Data from 7 studies with a total of 965 children with psoriasis were analysed using a random effects model. RESULTS: Prevalence of metabolic syndrome (MetS) was significantly higher in patients with psoriasis than in healthy controls (HCs)...
January 2, 2017: Clinical and Experimental Dermatology
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