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Clinical and Experimental Dermatology

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https://www.readbyqxmd.com/read/27917526/a-painful-leg-ulcer
#1
T King, R A Carr, M Sharma
No abstract text is available yet for this article.
December 5, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27917524/recurrent-oral-ulcers-and-blisters-in-a-young-woman
#2
C H Chu, P K Tuan, Y P Cheng, J Y Chan, C Y Chou
No abstract text is available yet for this article.
December 5, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27917523/a-curious-case-of-blinking-bottom
#3
H Rajgopal Bala, C C Wong, S J Robertson
No abstract text is available yet for this article.
December 5, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27917516/idiopathic-eruptive-macular-pigmentation-with-papillomatosis
#4
LETTER
M Ghiasi, K Kamyab
No abstract text is available yet for this article.
December 5, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27917514/vulvar-basal-cell-carcinoma-with-adhesion-of-the-labia-majora-and-minora
#5
LETTER
S Saito, H Hata, Y Inamura, S Kitamura, T Yanagi, H Shimizu
No abstract text is available yet for this article.
December 5, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27910137/amelanotic-naevoid-melanoma-in-a-16-month-old-albino-infant
#6
N Knöpfel, A Martín-Santiago, L J Del Pozo, C Saus, M Pascual, L Requena
Melanoma in individuals with oculocutaneous albinism has been reported in the literature to be rare compared with the more common occurrence of squamous cell carcinoma and basal cell carcinoma. We present a singular case of amelanotic naevoid melanoma arising from a small congenital naevus in a 16-month old albino boy, the youngest reported to date.
December 2, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27910130/necrotizing-eosinophilic-folliculitis-a-new-manifestation-of-the-atopic-diathesis
#7
LETTER
F Cunningham, P Gupta, G Becher, C M Magro
No abstract text is available yet for this article.
December 2, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27910127/treatment-of-severe-chronic-hand-eczema-results-from-a-uk-wide-survey
#8
I L Smith, S Brown, J Nixon, F C Cowdell, S Ersser, C Fernandez, M Goodfield, C M Green, P Hampton, J T Lear, C H Smith, L Sunderland, S Tubeuf, M Wittmann
Treatment of severe hand eczema (HE) that is resistant to topical potent corticosteroid treatment is challenging. In 2013, we surveyed 194 UK dermatologists to obtain information about their usual treatment pathways to inform the choice of the comparator in a trial of alitretinoin in severe HE (ALPHA trial); the results indicated that the treatment approaches favoured by UK dermatologists differ. Psoralen combined with ultraviolet A (PUVA) and alitretinoin were identified as the most frequent first-line treatment options for hyperkeratotic HE, whereas oral corticosteroids were identified as the most frequent first-line treatment for vesicular HE, followed by PUVA and alitretinoin...
December 2, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27910124/a-case-of-melanoma-seeding-along-a-biopsy-tract
#9
LETTER
D Trokoudes, J Weir, A Chu, R Patalay
No abstract text is available yet for this article.
December 2, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27905142/despite-numerous-recent-advances-in-dermatological-therapy-the-need-for-inpatient-dermatology-care-remains-considerable
#10
LETTER
L Nemazee, P J Hampton
No abstract text is available yet for this article.
December 1, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27905158/metastatic-spinal-cord-compression-from-basal-cell-carcinoma-of-the-skin-treated-with-surgical-decompression-and-vismodegib-case-report-and-review-of-hedgehog-signalling-pathway-inhibition-in-advanced-basal-cell-carcinoma
#11
J McGrane, S Carswell, T Talbot
We report a case of a 66-year-old man with locally advanced and metastatic basal cell carcinoma (BCC) causing spinal cord compression, which was treated with spinal surgery and subsequent vismodegib. The patient presented with a large fungating chest wall lesion and a metastasis in T8 that was causing cord compression. He had neurosurgical decompression of the T8 lesion and fixation of the spine. Punch biopsy from the fungating chest wall lesion showed a BCC with some malignant squamous differentiation (basosquamous)...
November 30, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27905128/ehlers-danlos-syndrome-related-to-fkbp14-mutations-detailed-cutaneous-phenotype
#12
A C Bursztejn, M Baumann, D Lipsker
In 2012, a new Ehlers-Danlos (ED) variant, characterized by severe progressive kyphoscoliosis, neonatal myopathy and hearing loss, with normal urinary lysylpyridinoline to hydroxylysylpyridinoline ratio and most often a recurrent homozygous mutation in the FKBP14 gene, was reported. Because one of the major affected tissues in ED syndrome is the skin, recognition of the cutaneous features of this newly recognized EDS variant is important. We describe the cutaneous phenotype of an adolescent girl harbouring the recurrent homozygous FKBP14 mutation...
November 30, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27900796/parvovirus-b19-infection-presenting-concurrently-as-papular-purpuric-gloves-and-socks-syndrome-and-bathing-trunk-eruption
#13
I Vázquez-Osorio, S Mallo-García, E Rodríguez-Díaz, P Gonzalvo-Rodríguez, L Requena
Parvovirus B19 infection can cause a wide range of cutaneous manifestations, including papular-purpuric gloves-and-socks syndrome (PPGSS) and petechial bathing trunk eruption. We report a case of an immunocompetent woman with a primary parvovirus B19 infection presenting as concurrent PPGSS and petechial bathing trunk eruption. Parvovirus B19 seroconversion was confirmed several days after the onset of the clinical manifestations. The coexistence of these two cutaneous manifestations of primary parvovirus B19 infection has rarely been reported in the literature...
November 30, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27900779/mosaic-nras-q61r-mutation-in-a-child-with-giant-congenital-melanocytic-naevus-epidermal-naevus-syndrome-and-hypophosphataemic-rickets
#14
R Ramesh, N Shaw, E K Miles, B Richard, I Colmenero, C Moss
The association of hypophosphataemic rickets with verrucous epidermal naevus (EN) and elevated fibroblast growth factor 23 levels is known as cutaneous-skeletal hypophosphataemia syndrome (CSHS), and can be caused by somatic activating mutations in RAS genes. We report a unique patient with CSHS associated with giant congenital melanocytic naevus (CMN), neurocutaneous melanosis and EN syndrome, manifesting as facial linear sebaceous naevus, developmental delay and ocular dermoids. An activating mutation Q61R in the NRAS gene was found in affected skin and ocular tissue but not blood, implying that the disparate manifestations are due to a multilineage activating mutation (mosaic RASopathy)...
November 30, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27896859/paraneoplastic-pityriasis-rubra-pilaris-case-report-and-literature-review
#15
E Bar-Ilan, A Gat, E Sprecher, T Zeeli
Pityriasis rubra pilaris (PRP; MIM 173200) is an uncommon papulosquamous inflammatory dermatosis. Only a few cases of PRP associated with an underlying malignancy have been documented. We investigated a 59-year-old patient presenting with a fulminant form of PRP recalcitrant to systemic retinoid therapy, in whom the skin disease heralded a diagnosis of cholangiocarcinoma. We searched the MEDLINE database to find articles reporting on similar associations of PRP with malignancies. We identified 10 studies linking PRP and malignancies, but an association between PRP and cholangiocarcinoma has not yet been reported...
November 29, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27896847/a-case-of-leucocytoclastic-vasculitis-as-a-complication-of-igg4-related-skin-disease
#16
S Nakagawa, Y Nakamura, S Yasui, O Yokosuka, H Matsue
No abstract text is available yet for this article.
November 29, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27868221/what-s-new-in-atopic-eczema-an-analysis-of-systematic-reviews-published-in-2014-part-2-treatment-and-prevention
#17
REVIEW
A Lloyd-Lavery, N K Rogers, S J Hatfield, D Grindlay, R Barnett, K S Thomas
This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE). It provides a summary of key findings from 12 systematic reviews (SRs) that were published or indexed during 2014, and focuses on the treatment and prevention of AE. For an update of SRs on the epidemiology, mechanisms of disease and methodological issues, see Part 1 of this update. Although phototherapy and various systemic medications (including ciclosporin, azathioprine and methotrexate) are commonly used to treat AE, many of these have not been robustly assessed in head-to-head randomized controlled trials...
November 21, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27859464/modification-of-the-double-purse-string-suture-for-the-excision-of-a-large-pigmented-naevus-on-the-buttock
#18
H F Sun, D M He, H S Lu, D X Wu
No abstract text is available yet for this article.
November 17, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27862169/erosive-pustular-dermatosis-of-the-scalp-developing-after-a-burn-from-a-hair-bleaching-procedure
#19
C Pernet, D Bessis, O Dereure, N Raison-Peyron
No abstract text is available yet for this article.
November 15, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27862168/late-onset-bulky-naevocytoma-of-the-perineum-masquerading-as-a-malignant-melanoma
#20
J W Huh, J Yoo, M S Kim, K H Choi, M S Jue, H J Park
Bulky naevocytoma of the perineum is a very rare variant of giant congenital melanocytic naevus (GCMN). It presents as a bulky naevocytic tumour in the perineal region with characteristic histological findings, such as extensive areas with a neural appearance called 'lames foliacees', formation of a pseudofollicular structure and extension of naevus cells between collagen bundles in a row called 'Indian-file' pattern. We report a case of late-onset bulky naevocytoma of the perineum in a 13-year-old girl. The patient presented with two bulky, pedunculated, heavily pigmented masses in the vulvar area that developed in a pre-existing GCMN lesion, which began around puberty and caused severe gait disturbance...
November 15, 2016: Clinical and Experimental Dermatology
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