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Clinical and Experimental Dermatology

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https://www.readbyqxmd.com/read/29465162/radiotherapy-induced-morphoea-of-the-breast-responding-to-photodynamic-therapy
#1
M Papanikolaou, Z Tsianou, A M Skellett, J Murphy, G W M Millington
No abstract text is available yet for this article.
February 21, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29464730/demyelination-during-anti-tumour-necrosis-factor-therapy-for-psoriasis
#2
J M E Boggs, L Barnes
Anti-tumour necrosis factor (anti-TNF) therapies have been associated with neurological complications, including in rare cases demyelinating disease. It is currently unknown whether patients who have received more than one immunosuppressive agent or anti-TNF have a greater risk of demyelination. We report the case of a 37-year-old woman with psoriasis who presented with an acute episode of demyelination while on anti-TNF therapy. This case was complicated by the fact that progressive multifocal leukoencephalopathy was considered the likely diagnosis initially and was only definitively excluded by brain biopsy...
February 21, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29460979/management-of-naevus-sebaceous-a-national-survey-of-uk-dermatologists-and-plastic-surgeons
#3
G N Wali, S J Felton, T McPherson
Naevus sebaceous (NS) is a congenital cutaneous hamartoma, which typically occurs on the head and neck. Historically, the treatment of choice was excision in infancy because of the potential for malignant transformation; however, recent studies suggest that this risk is < 1% and unlikely in childhood. We sent a questionnaire to UK dermatologists and plastic surgeons to investigate current management practice of NS. We found that almost a third of dermatologists still recommend excision for malignancy prevention, while over 90% of plastic surgeons consider excision, with 64% citing malignancy prevention as the reason...
February 20, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29460978/use-of-tisseel-fibrin-glue-for-a-recurrent-cheek-haematoma-after-mohs-micrographic-surgery
#4
LETTER
P S A Jayasekera, C M Lawrence
No abstract text is available yet for this article.
February 20, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29460435/topical-pimecrolimus-for-paediatric-cutaneous-mastocytosis
#5
J Mashiah, A Harel, C Bodemer, S Hadj-Rabia, I Goldberg, E Sprecher, A Kutz
BACKGROUND: Most cases of paediatric cutaneous mastocytosis (CM) occur before the age of 2 years, and regression occurs in only 67% of children. Given the absence of any specific therapy, CM is usually treated symptomatically. A few publications have reported the beneficial effect of calcineurin inhibitors for CM. AIM: We sought to evaluate the clinical effectiveness and safety profile of topical pimecrolimus cream for the treatment of CM. METHODS: We performed a retrospective study of all diagnosed cases of CM treated with topical pimecrolimus 1% cream between 2013 and 2015...
February 20, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29460336/emollient-product-design-objective-measurements-of-formulation-structure-texture-and-performance-and-subjective-assessments-of-user-acceptability
#6
M D Antonijević, S Owusu-Ware, B Sanchon-Lopez
BACKGROUND: The choice of prescribed emollients is usually based on cost and patient preference. Differences in formulations can affect user acceptability. AIM: To compare the physical performance, user acceptability and various product design features of two emollient gels that are prescribed in the UK and alleged to be therapeutically interchangeable because their formulations are described as having the same contents of oily ingredients. RESULTS: We found that here are in fact significant measurable differences between the structure and performance of the two formulations, which materially affect their user acceptability...
February 20, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29457251/involvement-of-flexures-in-an-adolescent-patient-with-dermatomyositis-extension-of-inverse-gottron-papules
#7
A Bishnoi, D Parsad, U N Saikia
No abstract text is available yet for this article.
February 19, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29453771/rapid-improvement-of-nail-matrix-psoriasis-with-apremilast-clinical-and-ultrasonographic-assessment
#8
LETTER
C Muñoz-Santos, J Sola-Ortigosa, A Guilabert
No abstract text is available yet for this article.
February 16, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29453770/nivolumab-induced-lichenoid-dermatitis-occurring-in-a-patient-with-metastatic-melanoma-successfully-treated-with-alitretinoin
#9
LETTER
C Edwards, L Fearfield
No abstract text is available yet for this article.
February 16, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29451318/effective-management-of-severe-cutaneous-mastocytosis-in-young-children-with-omalizumab-xolair-%C3%A2
#10
J D M Hughes, T Olynyc, H Chapdelaine, L Segal, B Miedzybrodzki, M Ben-Shoshan
Omalizumab (Xolair ® ) is an anti-IgE monoclonal antibody, which may benefit adults with systemic mastocytosis. We report effective treatment with omalizumab in two toddlers with severe diffuse cutaneous mastocytosis. Our cases offer preliminary evidence to support the safe use of omalizumab in paediatric patients with cutaneous mastocytosis.
February 16, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29450912/association-of-clinicopathological-features-of-melanoma-with-total-naevus-count-and-a-history-of-dysplastic-naevi-a-cross-sectional-retrospective-study-within-an-academic-centre
#11
S Y Tan, L C Strazzulla, X Li, J J Park, S J Lee, C C Kim
BACKGROUND: High naevus count (HNC) (≥ 50 naevi) and presence of dysplastic naevi (DN) are risk factors for malignant melanoma (MM); however, MMs also occur in patients with low naevus count (LNC) (< 50 naevi) and in patients without DN. Little is known about differences between MMs in these groups. AIM: To characterize the clinicopathological differences between MMs in patients with HNC and those in patients with LNC, with or without biopsy-proven DN. METHODS: This was a cross-sectional retrospective chart review of 281 patients with MM seen between April 2013 and March 2014 at an academic pigmented lesion clinic (Boston, MA, USA)...
February 16, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29450908/aquagenic-pruritus-successfully-treated-with-omalizumab
#12
B Murphy, M Duffin, J Tolland
No abstract text is available yet for this article.
February 16, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29446475/an-audit-of-compliance-with-tuberculosis-screening-prior-to-treatment-with-biologics-in-psoriasis
#13
LETTER
A Kelly, B Kirby
No abstract text is available yet for this article.
February 15, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29446473/a-case-of-kaposi-varicelliform-eruption-progressing-to-herpes-simplex-virus-hepatitis-in-an-immunocompetent-patient
#14
M Okamoto, S Takahagi, A Tanaka, A Ogawa, H Nobuki, M Hide
No abstract text is available yet for this article.
February 15, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29441611/asymptomatic-facial-nodules
#15
S Sherif, L Pareja-Cebrian, M Alemkunnapuzha, N Usmani
No abstract text is available yet for this article.
February 14, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29436013/time-resolved-fluorescence-spectroscopy-for-the-diagnosis-of-oral-lichen-planus
#16
D Gorpas, P Davari, J Bec, M A Fung, L Marcu, D G Farwell, N Fazel
BACKGROUND: Lichen planus (LP) is a T-cell mediated autoimmune disorder of unknown aetiology that affects the skin, nails, oral and genital mucous membranes. Conventionally, oral LP (OLP) is diagnosed through clinical assessment and histopathological confirmation by oral biopsy. AIM: To explore the use of time-resolved fluorescence spectroscopy (TRFS) to detect fluorescence lifetime changes between lesional OLP and perilesional normal mucosa. METHODS: In this pilot study, measurements of lesional and perilesional buccal and mouth floor mucosa were conducted in vivo with a TRFS system...
February 13, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29430689/dystrophic-calcinosis-cutis-within-burns-successfully-treated-with-excision-and-secondary-intention-wound-healing
#17
K A Lockwood, T Oliphant
No abstract text is available yet for this article.
February 12, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29427327/systemic-juvenile-xanthogranuloma-a-case-report-and-brief-review
#18
M Meyer, A Grimes, E Becker, J Browning, C Assanasen, L Libow, T DeNapoli
No abstract text is available yet for this article.
February 10, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29427316/first-report-of-col7a1-mutations-in-two-patients-with-recessive-dystrophic-epidermolysis-bullosa-from-peru
#19
LETTER
A H Saeidian, L Youssefian, G M Rosales-Solis, H Vahidnezhad, V S Atanasova, J Uitto, A P South, J C Salas-Alanis
No abstract text is available yet for this article.
February 9, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29424103/alternative-activation-of-hedgehog-pathway-induced-by-ultraviolet-b-radiation-preliminary-study
#20
A Lesiak, D Sobolewska-Sztychny, I A Bednarski, K Wódz, M Sobjanek, A Woźniacka, J Narbutt
BACKGROUND: There is still much ambiguity in studies of Sonic hedgehog (Shh) pathways and its dysregulation. Some studies concerning the role of the Shh pathway in basal cell carcinoma (BCC) have been conducted, but there is a lack of studies about Shh pathway dysregulation under the influence of ultraviolet (UV)B radiation. AIM: To evaluate skin expression of Shh, Ptch1, Ptch2, Smo and Gli1 proteins in BCCs with and without the influence of UVB radiation. METHODS: In total, 34 healthy controls (HCs) and 42 patients with nodular BCC were recruited into the study...
February 9, 2018: Clinical and Experimental Dermatology
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