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Sachin K Chandavarkar, S N Mamle Desai
INTRODUCTION: Drugs that induce diuresis are known as diuretics. Diuretic drugs act either by increasing the glomerular filtration rate (or) by decreasing the rate of reabsorption of fluid from the tubules. In recent years, interest in herbal agents as therapeutic treatment option has increased due to their limited side effects. AIM: To evaluate the diuretic activity of various extracts of whole plant of Biophytum sensitivum (Linn.) DC. in Wistar strain albino rats...
July 2015: Ayu
Ahamed Shahan Ajmeer, Tukaram S Dudhamal, Sanjay Kumar Gupta
INTRODUCTION: Prevalence of diabetes and its complications have been a burden to the society from the ancient times, in the present and also will be in the future unless proper measures are taken to prevent its manifestation. There have been an increasing number of death associated-amputation cases which are mainly caused by nonhealing wounds. These facts urge researchers to develop new, more effective wound treatments for diabetic patients. AIM: To evaluate and compare the effect of Katupila Kalka (Securinega leucopyrus [Willd...
July 2015: Ayu
Md Nafiujjaman, Md Nurunnabi, Samir Kumar Saha, Rownak Jahan, Yong-Kyu Lee, Mohammed Rahmatullah
INTRODUCTION: Though metal based drugs have been prescribed in Ayurveda for centuries to treat various diseases, such as rheumatoid arthritis and cancer, toxicity of these drugs containing heavy metal is a great drawback for practical application. So, proper scientific validation of herbo-metallic drugs like Arkeshwara Rasa (AR) have become one of the focused research arena of new drugs against cancers. AIM: To investigate the in vitro anticancer effects of AR. MATERIALS AND METHODS: Anticancer activity of AR was investigated on two human cancer cell lines, which represent two different tissues (pancreas and skin)...
July 2015: Ayu
Rohit Kumar, Vinod Nair, Surender Singh, Yogendra Kumar Gupta
INTRODUCTION: Rosa centifolia L. (Rosaceae) have been used for the treatment of joint pain and rheumatoid arthritis (RA) in the traditional system of medicine. AIM: In this study, the antiarthritic activity of the alcoholic extract from the floral parts of R. centifolia was investigated. MATERIALS AND METHODS: The anti-inflammatory and antiarthritic activity of R. centifolia alcoholic extract (RCAE: 32, 64, and 128 mg/kg) was evaluated using the carrageenan-induced paw edema and complete Freund's adjuvant (CFA) induced arthritis model...
July 2015: Ayu
Priyank A Patel, Mihir P Parikh, Sarika Johari, Tejal R Gandhi
INTRODUCTION: Albizzia lebbeck (L.) Benth. (Family - Leguminosae) extract is a proven mast cell stabilizing agent. Mast cells are involved in the inflammatory processes leading to the diabetes mellitus. AIM: To evaluate the effect of A. lebbeck against experimentally induced type 2 diabetes mellitus in rats. MATERIALS AND METHOD: Female Sprague-Dawley rats were randomly allocated to six groups (n = 6). Diabetes was induced by single intraperitoneal injection of streptozotocin (50 mg/kg) given after 15 min of nicotinamide administration (110 mg/kg)...
July 2015: Ayu
Dushyant Kumar, Paragouda A Patil, Subarna Roy, Sanjiv D Kholkute, Harsha V Hegde, Vinod Nair
INTRODUCTION: The root of Plumbago zeylanica Linn. is used in traditional medicine for the treatment of chronic inflammatory diseases and various disorders. The toxicity of this plant has not yet been extensively evaluated. AIM: To evaluate and compare the toxicity of P. zeylanica root petroleum ether (PZPE), acetone (PZAC), and the hydroalcoholic (PZHY) extracts. MATERIALS AND METHODS: The acute and sub-acute toxicities of extracts were evaluated according to OECD guidelines 425 and 407, respectively in female rats...
July 2015: Ayu
S Rejitha, P Prathibha, Indira Madambath
INTRODUCTION: Most of the pharmaceutical effects of alcohol are due to its accumulation in the brain. Ksheerabala (101) an Ayurvedic formulation mainly used against central nervous system disorders. AIM: To determine the antioxidant and neuroprotective effect of Ksheerabala (101) on alcohol-induced oxidative stress in rats. MATERIALS AND METHODS: Male Albino rats of Sprague-Dawley strain were grouped into four; control, alcohol (4 g/kg), Ksheerabala (15 μL/1 ml milk/100 g) and Ksheerabala (15 μL/1 ml milk/100 g) + alcohol (4 g/kg)...
July 2015: Ayu
Ganesh Muguli, Vishakante D Gowda, Vishnu Dutta, Atul N Jadhav, Bibhilesh B Mendhe, Rangesh Paramesh, U V Babu
INTRODUCTION: Ayurvedic texts describe many formulations for different ailments. Triphala Guggulu (TG) is reputed for treating inflammatory conditions. These formulations have been considered complementary medicine or alternative to conventional medicines across the globe. These complex polyherbal formulations need science-based approach toward manufacturing process and chemical standardization. AIM: To evaluate TG tablets to meet modern pharmaceutical approaches and also standardization processes...
July 2015: Ayu
Asmita A Wele, Nikhil U Pendse, Shrikant P Takle, Raghunath V Burase, Sanjay V Patil, Supriya Bhalerao, Abhay M Harsulkar
INTRODUCTION: Vasarishta built upon Mritasanjeevani Sura (MS) is a polyherbal hydro-alcoholic anti-asthmatic formulation which is administered in a dose of 1 ml instead of standard dose 40 ml, generally advocated for any "Asava-Arishta" in Ayurveda. AIM: The present study was aimed at finding out rationale for the peculiar distillation process to manufacture MS followed by Sthapana process to make Vasarishta. It was further aimed to find out difference in Vasarishta samples manufactured by purely fermentation process and the peculiar method mentioned above...
July 2015: Ayu
K N Sunil Kumar, Priyadarshini Pushpendra, B S Holla, B Ravishankar, B Yashovarma
INTRODUCTION: Measuring chemical stability of polyherbal formulations is very challenging due to diversity in phytochemical composition. As there are no comprehensive guidelines for stability testing of herbal products, there is a need for a sensitive tool to detect how the quality of herbal products varies with time under the influence of environmental conditions. AIMS: To validate the employability of high-performance thin layer chromatography (HPTLC) for real-time stability of Hutabhugadi Churna (HC)...
July 2015: Ayu
Sneha D Borkar, Raghavendra Naik, Vinay J Shukla, Rabinarayan Acharya
BACKGROUND: Rivea hypocrateriformis (Desr.) Choisy is known to be the source plant of Phanji, a classically delineated leafy vegetable which is till date used by some hill dwelling Kandha tribes of Odisha. Though it is in use since a long time, it is not yet evaluated for its nutritive value. AIM: The leaves of R. hypocrateriformis were evaluated for its nutritive value and antioxidant potential. MATERIALS AND METHODS: The in vitro antioxidant properties of the leaf of R...
July 2015: Ayu
Shaizi Layeeq, Anup B Thakar
INTRODUCTION: Iron deficiency anemia (IDA) is one of the most common nutritional deficiencies worldwide, which can be correlated to Pandu described in ayurvedic classics. Poor absorption of iron is one of the main reasons of IDA. Amalaki (Phyllanthus emblica L.) has Tridoshahara, especially Pittashamaka (pacifying Pitta) and Rasayana (rejuvenative) properties, thus nourishes the Dhatus and is also known to enhance the absorption of iron. AIMS: To evaluate the efficacy of Amalaki Rasayana in the management of Pandu w...
July 2015: Ayu
Hitesh Bhati, R Manjusha
INTRODUCTION: Senile cataract is the leading cause of blindness according to the World Health Report, 1998. Till date no accepted medical treatment is available for cataract. In Ayurveda visual disturbances are described in the context of Timira, Kacha and Linganasha. Timira is an early stage characterized by blurring of vision and Linganasha is end stage where complete loss of vision occurs. Ancient scholars have advocated different Anjana application and oral medications in the Timira and Kacha stage...
July 2015: Ayu
Vishal Arya, Lavina Taneja
INTRODUCTION: Dental caries is a universal disease. Dietary modification is important in reducing the occurrence of dental caries. Tea which is so frequently consumed with cariogenic starch rich food is proposed to have anticariogenic potential. The various mechanism has been proposed for same and one being inhibition of salivary amylase activity. AIM: To determine the effect of 1.5% black tea decoction on salivary amylase activity in children with high caries and no caries...
July 2015: Ayu
Ankit M Paneliya, Biswajyoti Patgiri, R Galib, Pradeep Kumar Prajapati
INTRODUCTION: Bronchial asthma is one of the chronic inflammatory disorders of the respiratory tract causing a huge number of deaths annually. Increased industrialization and pollution are the exacerbating factors for this situation. In Ayurveda, this miserable condition is comparable with Tamaka Shwasa. Synthetic drugs provide instant symptomatic relief in cases of bronchial asthma but are known to develop certain adverse drug reactions. Considering this, the current suffering population is looking hopefully towards other systems of medicine such as Ayurveda for better relief...
July 2015: Ayu
Bharat A Salve, Raakhi K Tripathi, Anup U Petare, Ashwinikumar A Raut, Nirmala N Rege
INTRODUCTION: In Ayurveda Tinospora cordifolia (Willd.) Miers., has been used for its Rasayana, Deepana, Jwaranashana, Tridosha Shamaka properties. It is an immunomodulator, useful in stress, hyperlipidemia, pyrexia. T. cordifolia was evaluated for adaptogenic activity in healthy volunteers during exercise. AIMS: The primary objective of this study was to evaluate the effect of T. cordifolia on physical performance, and secondary objectives were to evaluate muscle power, maximal oxygen consumption, and sympathetic activity in comparison with placebo when subjected to physical stress...
July 2015: Ayu
Swagata D Tavhare, K Nishteswar, Vinay J Shukla
INTRODUCTION: Ayurvedic classics have advocated to collect the medicinal plants according to part used and seasons in order to get desired pharmacological action and therapeutic benefits. The logic behind this principle is being validated by recent researches. AIM: To analyze the influence of lunar cycles on growth of Ashwagandha in Shishira and Greeshma Ritu (winter and summer season). MATERIALS AND METHODS: Fourteen small crops of Ashwagandha of average size 10 cm were collected on October 7, 2013, from institute campus and then replantation was done at Charaka Herbal Garden, Gujarat Ayurved University, Jamnagar in an area of 60 cm × 60 cm (l × b)...
July 2015: Ayu
Pravin M Bolshete
INTRODUCTION: Reporting of ethical approval and informed consent in clinical research articles involving human subjects is necessary as per the International Committee of Medical Journal Editors (ICMJE). AIM: To assess the reporting of ethics committee approval and informed consent in clinical research articles published in AYU journal. MATERIALS AND METHODS: This was a retrospective analysis of published articles in AYU from 2012 to 2014...
July 2015: Ayu
Madhur G Aggithaya, Saravu R Narahari
INTRODUCTION: The journals that publish on Ayurveda are increasingly indexed by popular medical databases in recent years. However, many Eastern journals are not indexed biomedical journal databases such as PubMed. Literature searches for Ayurveda continue to be challenging due to the nonavailability of active, unbiased dedicated databases for Ayurvedic literature. In 2010, authors identified 46 databases that can be used for systematic search of Ayurvedic papers and theses. This update reviewed our previous recommendation and identified current and relevant databases...
July 2015: Ayu
Hari Sharma
Meditation has become popular in many Western nations, especially the USA. An increasing body of research shows various health benefits associated with meditation and these findings have sparked interest in the field of medicine. The practice of meditation originated in the ancient Vedic times of India and is described in the ancient Vedic texts. Meditation is one of the modalities used in Ayurveda (Science of Life), the comprehensive, natural health care system that originated in the ancient Vedic times of India...
July 2015: Ayu
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