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Anjan Adhikari, Moumita Ray, Anup Kumar Das, Tapas Kumar Sur
BACKGROUND: Rhizophora mucronata is a salt-tolerant true mangrove which is widely distributed in Indian mangrove forest and traditionally used to treat diabetes and other health ailments. AIM: The aim of this study is to elucidate the role of Indian variety of R. mucronata leaves on glucose impairing metabolism during diabetes by in vitro and in vivo methods. MATERIALS AND METHODS: The ethanolic fraction of R. mucronata leaves extract (RHE) was assessed for DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging and in vitro anti-diabetic action through α-amylase and α-glucosidase activity assessment...
January 2016: Ayu
Revati Sharma, Ahsan Bhatt, Mansee Thakur
INTRODUCTION: Bhasma, an Ayurvedic metallo-mineral preparation, is claimed to be biologically produced nanoparticles. Rajata (silver) is a noble metal known for its antimicrobial activity. Rajata Bhasma (RB) is expected to be composed of nanoparticles. With all these facts in place, this study was conducted to evaluate RB for the presence of silver nanoparticle (SNP) and its antimicrobial effect. AIM: The aim of this study is to analyze the physicochemical characterization, antibacterial activity of RB, and SNP...
January 2016: Ayu
Pankaj Pathak, Mahesh Vyas, Hitesh Vyas, Mukesh Naria
INTRODUCTION: The Drosophila melanogaster is one of the most extensively studied animal models for understanding the process of aging and longevity. This fly is being used for genetic studies since almost a century. Guduchi (Tinospora cordifolia [Wild.] Miers.) is an Ayurvedic drug used as Rasayana (rejuvenation) due to its antiaging effect. AIM: To explore the potential of Guduchi Churna (powder of T. cordifolia) on the life span of D. melanogaster using adult feeding method...
January 2016: Ayu
Suman G Singh, K Nishteswar, Bhupesh R Patel, Mukesh Nariya
BACKGROUND: Cissampelos pareira Linn. is considered as an established source of Patha, whereas Cyclea peltata (Lam.) Hook. F. & Thomas is used as a source plant of Patha in the southern part of India. In classical texts, two different varieties of Patha, i.e. Rajpatha (C. peltata) and Laghupatha (C. pareira), are mentioned which possess almost similar properties. OBJECTIVE: To compare antipyretic and analgesic activities of C. pareira and C. peltata in suitable experimental model...
January 2016: Ayu
Kshirod Kumar Ratha, Laxmidhar Barik, Ashok Kumar Panda, Jayram Hazra
Ayurvedic medicines are often considered effective for chronic and lifestyle disorders. Hypertrophic lichen planus (HLP) is a rare inflammatory skin condition and develops into squamous cell carcinoma in few cases. It has resemblance with Charma Kushtha mentioned in Ayurvedic classics. Conventional therapy used in this condition is unsatisfactory and is not free from side effects. A case of long-standing systemic steroid-dependent HLP is presented here which was intervened successfully with Ayurvedic modalities...
January 2016: Ayu
Saylee Deshmukh, Mahesh K Vyas, R R Dwivedi, Hitesh A Vyas
BACKGROUND: Non-communicable diseases are expected to kill more people in the 21(st) century which are the resultant of deranged lifestyle such as unhealthy dietary habits and wrong behavioral pattern. In Ayurveda, Ahara Vidhi (dietary rules) and Vihara (conducts) are described in detail which can be included under the heading of lifestyle. Agnimandya (indigestion) is considered as the root cause of all diseases like diabetes mellitus, obesity etc., which are few among the top ten lifestyle disorders...
January 2016: Ayu
Aneesh Vasudeva Sharma, Tukaram Sambhaji Dudhamal, Sanjay Kumar Gupta, Vyasadeva Mahanta
BACKGROUND: Sandhivata is a disease described under Vatavyadhi and resembles osteoarthritis (OA) in respect to etiology, pathology, and clinical features. Knee joints are more prone to be affected by this disease because it is the most frequently involved joint in daily works. Acharya Sushruta has indicated Agnikarma, when severe pain occurs in Twak, Mamsa, Sira, Snayu, Sandhi, and Asthi due to Vata Prakopa. Panchatikta Guggulu is a formulation mentioned in Chakradatta and Bhaishajya Ratnavali in the context of Kushtha Roga where it is also indicated for Sandhigata Vata and Asthigata Vata...
January 2016: Ayu
B A Pooja, Santosh Kumar Bhatted
BACKGROUND: Dyslipidemia, a major risk factor of coronary heart disease, is the leading single cause of death in the world. Currently available hypolipidemic agents have been associated with a large number of side effects. The radical Ayurveda Samshodhana Chikitsa as a treatment protocol can provide better effect. Therefore, the present study was designed to evaluate the effect of Virechana Karma and Lekhana Basti in dyslipidemia. OBJECTIVES: To evaluate the effect of Virechana Karma and Lekhana Basti in the management of dyslipidemia (Medoroga)...
January 2016: Ayu
Minakshi Kumbhare-Patil, Dhanraj B Gahukar, Swapnil N Patil
INTRODUCTION: The incidence rate of Gridhrasi (sciatica) is quite significant as more than three-quarters of the world's population are affected by the disease. It is characterized by the onset of Ruja (pain), Toda (pricking), and Stambha (stiffness), initially in Sphika (gluteal region) and then radiating distally to Kati-Prishtha (low back), Janu (knee), Jangha (thigh) till Pada (feet). The patients suffering from Gridhrasi have restricted movements due to painful limb, affecting the daily routine activities...
January 2016: Ayu
Ravishankar Tejvani, Kashinath G Metri, Jyotsna Agrawal, H R Nagendra
INTRODUCTION: There has been an increase in a number of orphanages and children living in orphanages in last few years. The children living in orphanages often have psychological problems among which anxiety, depression, and low self-esteem are considered to be most prominent. Yoga is a noninvasive, cost-effective, and safe intervention among complementary and alternative medicine which is known to have a positive impact on psychological problems. AIMS: The present pilot study intended to assess the effect of a two week Yoga intervention on anxiety, depression, and self-esteem of adolescents and young adults living in an orphanage...
January 2016: Ayu
Shalini Rai, Anukul Chanda Kar
"Pandu" Roga is a disease entity described in Ayurveda which has clinical features similar to that of various types of anemia, in which there develops a pale-yellow discoloration on the skin. Besides the various etiological factors, Acharya Charaka has specially described some psychological causative factors among which Chinta (excessive worry), Bhaya (fear) and Shoka (grief) are three main factors, which play an important role in the pathogenesis of Pandu Roga. This paper aims to explore the scientific explanations for the above stated factors in the causation of Pandu Roga (anemia)...
January 2016: Ayu
Ahalya Sharma, T V Shalini, S J Sriranjini, B A Venkatesh
INTRODUCTION: Ayurveda has described about the pathogenesis and the treatment of various disorders, the incidence of some of which have increased in the present scenario. Janu Sandhigata Vata correlated with osteoarthritis (OA) of the knee joint is one such chronic, degenerative, inflammatory disease which has a great impact on the quality of the life of an individual. Different modalities of treatment have been explained in the classics to tackle the condition effectively. METHODOLOGY: In the present study, an attempt has been made to review the various clinical research works done in the management of OA of the knee, which are registered in various research portal...
January 2016: Ayu
Satyapal Singh, J S Tripathi, N P Rai
The concept of bioavailability enhancer is new to the modern system of medicine. Basically, this concept originated in Ayurveda and being used in this system of medicine since centuries. Bio-enhancers augment the bioavailability or biological activity of drugs when co-administered with principal drug at low doses. Ayurveda is using several drugs such as Piper longum Linn., Zingiber officinale Rosc., and Glycyrhhiza glabra Linn. as bio-enhancers and different methods for bio-enhancing since centuries. The bio-enhancement leads to reduction in therapeutic dose of principal drug, thus reducing the possibilities of toxicity and side effects of drug, potentiating the efficacy, reducing the resistance, decreasing the requirement of raw material for drug manufacture, and ultimately benefitting to the world economy by reducing the treatment cost...
January 2016: Ayu
Mahesh Vyas
No abstract text is available yet for this article.
January 2016: Ayu
Raghavendra Naik, Rabinarayan Acharya, Mukesh B Nariya, Sneha D Borkar
INTRODUCTION: Olax scandens Roxb. is a shrub or small tree found throughout tropical India. Fruits and leaves of this plant are used for medicinal and food purpose. Traditionally, leaves of O. scandens are used as vegetable in constipation. AIM: To evaluate the acute toxicity and intestinal transit time of O. scandens leaves on experimental animals. MATERIALS AND METHODS: Acute oral toxicity study for sample was carried out following OECD guidelines...
October 2015: Ayu
Prashant Y Mali
BACKGROUND: Portulaca oleracea Linn. (Portulacaceae) is commonly known as purslane in English. In traditional system it is used to cure diarrhea, dysentery, leprosy, ulcers, asthma, and piles, reduce small tumors and inflammations. AIM: To assess cytotoxic potential of chloroform extract of P. oleracea whole plant against human colon adenocarcinoma (HCT-15) and normal (Vero) cell line. MATERIALS AND METHODS: Characterization of chloroform extract of P...
October 2015: Ayu
Raxit P Rachchh, Varsha J Galani
INTRODUCTION: Grangea maderaspatana (L.) Poir. (Asteraceae), a popular Indian medicinal plant is traditionally used for rheumatism in the knee joint and pain in the muscles. AIM: To investigate antinociceptive and antirheumatic activity of G. maderaspatana (L.) Poir. using experimental models. MATERIALS AND METHODS: Antinociceptive activity of methanolic extract of G. maderaspatana (L.) Poir. (GMME) (500 mg/kg, 1000 mg/kg, p.o.) was evaluated in rats using tail flick test...
October 2015: Ayu
Shweta Chaudhary, Pawan Kumar Godatwar, Reetu Sharma
INTRODUCTION: Thrombotic disorders are among the major fatal conditions affecting the society. Treatment modalities used for such disorders are either surgical interventions or use of drugs such as urokinase, streptokinase (SK), or tissue plasminogen activators to dissolve the blood clots. These modalities have their own limitations and side effects apart from being expensive. There is a need for safer and cost effective antithrombolytic agents. AIM: To evaluate in vitro thrombolytic property of Dhamasa (Fagonia arabica Linn...
October 2015: Ayu
Nidhi Khemuka, R Galib, Biswa Jyoti Patgiri, Pradeep Kumar Prajapati
INTRODUCTION: Kamsaharitaki Avaleha is a well-known ayurvedic preparation. Considering certain inconveniences of Avaleha, an attempt has been made to convert it into granules that are convenient in handling, dispensing, and storage. AIM: To convert Kamsaharitaki Avaleha into granules form and develop standard manufacturing procedure. MATERIALS AND METHODS: Seven pilot batches were prepared to fix the ratio of formulation composition. The procedure was repeated for 14 times to ensure the process validation...
October 2015: Ayu
Sanjay Kumar Gupta, Anup B Thakar, Tukaram S Dudhamal, Aditya Nema
Amavata is a disease in which vitiation of Vata Dosha and accumulation of Ama take place in joint(s), and it simulates rheumatoid arthritis (RA) at modern parlance. Shamana (conservative) and Shodhana (biological purification of the body) treatments are advised in Ayurveda whereas anti-inflammatory, analgesics, steroids, and disease-modifying antirheumatic drugs are required for its management as per modern medicine, which are not free from side effects. A female was suffering from multiple joints pain with swelling, severe morning stiffness, restricted movements, malaise, and Mandagni (poor appetite) for the past 1½ year, which was classified as Amavata/RA (having 7/10 score as per the RA classification criteria, 2010)...
October 2015: Ayu
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