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European Journal of Pediatrics

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https://www.readbyqxmd.com/read/29143935/a-propensity-matched-comparison-of-hard-outcomes-in-children-on-chronic-dialysis
#1
Enrico Vidal, Nicholas C Chesnaye, Fabio Paglialonga, Bruno Minale, Giovanna Leozappa, Mario Giordano, Bruno Gianoglio, Ciro Corrado, Rosa Maria Roperto, Roberto Chimenz, Francesca Mencarelli, Ilse-Maria Ratsch, Luisa Murer, Enrico Verrina
Data concerning outcomes of children on hemodialysis (HD) and peritoneal dialysis (PD) are scarce and frequently derived from single-center experiences. We sought to compare survival and transplantation rates in a large cohort of PD and HD patients. We extracted all patients initiating dialysis under 16 years of age between 2004 and 2013 from the Italian Registry of Pediatric Chronic Dialysis. Patients on PD were propensity-matched to those on HD based on gender, age, primary cause of ESRD, and the number of co-morbidities...
November 16, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29128883/a-systematic-review-and-meta-analysis-of-the-effect-of-low-level-laser-therapy-lllt-on-chemotherapy-induced-oral-mucositis-in-pediatric-and-young-patients
#2
REVIEW
Mengxue He, Binghua Zhang, Nanping Shen, Na Wu, Jiwen Sun
Oral mucositis is one of the most frequent complications after chemotherapy, occurring in approximately 52 to 80% of children receiving treatment for cancer. Recently, it has been suggested that the use of low-energy laser could reduce the grade of oral mucositis and alleviate the symptoms. In 2014, Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology has recommended low-level laser therapy in prevention of mucositis for hematopoietic stem cell transplantation patients because of its beneficial effects in majority of recent studies...
November 11, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29127498/dynamics-in-prevalence-of-down-syndrome-in-children-with-congenital-heart-disease
#3
Constanze Pfitzer, Paul C Helm, Lisa-Maria Rosenthal, Felix Berger, Ulrike M M Bauer, Katharina Rl Schmitt
We assessed the dynamics in the prevalence of children with congenital heart disease (CHD) and Down syndrome in Germany with regard to phenotype, severity, and gender. Data from patients with CHD and Down syndrome born between 1980 and 2014 were analyzed, who are registered with the German National Register for Congenital Heart Defects. One thousand six hundred eighteen CHD patients with Down syndrome were identified. The prevalence of children born with both Down syndrome and CHD was constant from 2005 to 2009 but increased from 2010 to 2014...
November 10, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29124447/psychiatric-screening-and-interventions-for-minor-refugees-in-europe-an-overview-of-approaches-and-tools
#4
Annerieke Horlings, Irma Hein
Currently hundreds of thousands of minor refugees entered Europe. This group has been exposed to traumatic events pre-, during, and post-migration and is at increased risk of developing psychiatric disorders. In this article, we describe the results of our literature search on screening and interventions for post-traumatic stress disorder (PTSD) in minor refugees, in order to make recommendations for clinical practice. Results show that studies on diagnostic accuracy of assessment instruments and efficacy of mental healthcare interventions in this population are lacking...
November 10, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29124446/towards-better-healthcare-for-migrant-and-refugee-children-in-europe
#5
EDITORIAL
Albertine Baauw, Nicole Ritz
No abstract text is available yet for this article.
November 10, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29116397/do-we-need-repeated-weight-measurements-to-assess-dehydration-in-children-with-acute-gastroenteritis-at-the-emergency-department
#6
LETTER
Dorien Geurts, Henriëtte Moll, Rianne Oostenbrink
No abstract text is available yet for this article.
November 7, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29116396/length-of-stay-for-childbirth-in-trentino-north-east-of-italy-the-impact-of-maternal-characteristics-and-organizational-features-of-the-maternity-unit-on-the-probability-of-early-discharge-of-healthy-term-infants
#7
Riccardo Pertile, Lucia Pavanello, Massimo Soffiati, Laura Manica, Silvano Piffer
Early discharge (ED) of healthy term infants has become a common practice due to current social and economic needs. The primary objective of the present study was to evaluate trends in early discharge of healthy term neonates (≥ 37 gestational weeks) by delivery method (cesarean and vaginal) in maternity units in the Province of Trento. The secondary objective was to identify the socio-demographic characteristics (including the area of residence and distance from the designated hospital) and clinical characteristics of mothers whose infants were discharged early...
November 7, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29105029/correction-to-genetic-predisposition-in-children-with-cancer-affected-families-acceptance-of-trio-wes
#8
Triantafyllia Brozou, Julia Taeubner, Eunike Velleuer, Martin Dugas, Dagmar Wieczorek, Arndt Borkhardt, Michaela Kuhlen
The original version of this article, unfortunately, contained an error. The reference citations in the original paper are incorrectly cited to its corresponding bibliographic information. The original article was corrected.
November 6, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29103088/left-ventricular-functions-in-children-with-newly-diagnosed-graves-disease-a-single-center-study-from-upper-egypt
#9
Kotb Abbass Metwalley, Hekma Saad Farghaly, Abdelrahman Abdelhamid
This study aimed to evaluate the left ventricular (LV) functions in a cohort of children with Graves' disease (GD). This is a cross-sectional case-control study. It included 36 children with GD and 36 healthy children matched for age and gender. Thyroid hormones (TSH, FT4, and FT3) and anti-thyroid autoantibodies [anti-thyroid peroxidase (anti-TPO), thyrotropin receptor (TRAbs), and thyroglobulin antibodies] were measured. Conventional and tissue Doppler imaging (TDI) echocardiographies were used to assess left ventricular systolic and diastolic functions...
November 4, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29101451/the-influence-of-reducing-fever-on-blood-oxygen-saturation-in-children
#10
Shmuel Goldberg, Shmuel Heitner, Francis Mimouni, Leon Joseph, Reuben Bromiker, Elie Picard
Laboratory-based studies on the oxyhemoglobin dissociation curve (ODC) suggest that high blood temperature decreases the affinity of hemoglobin for oxygen. The aim of the study was to evaluate the influence of pyrexia on oxygen saturation (SpO2) in children presenting to the emergency department. Normoxemic children with body temperature at or above 38.5 °C were included. Patients with a dynamic respiratory disease were excluded. SpO2 was measured before and after antipyretic treatment. The changes in body temperature and SpO2 were assessed and compared to the changes predicted from the ODC...
November 3, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29101450/diet-in-pregnancy-more-than-food
#11
REVIEW
H Danielewicz, G Myszczyszyn, A Dębińska, A Myszkal, A Boznański, L Hirnle
High food quality, together with adequate macro- and micronutrient intake in pregnancy, is crucial for the health status of the mother and child. Recent findings suggest that it could also be beneficial or harmful in the context of the well-being of the whole future population. According to the developmental origins of health and disease hypothesis, most conditions that occur in adulthood originate in foetal life. Moreover, some epigenetic events, modified inter alia by diet, impact more than one generation...
November 3, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29090355/microbiological-comparison-of-blood-culture-and-amplification-of-16s-rdna-methods-in-combination-with-dgge-for-detection-of-neonatal-sepsis-in-blood-samples
#12
Isela García-Gudiño, Eucario Yllescas-Medrano, Rolando Maida-Claros, Diana Soriano-Becerril, Nestor F Díaz, Guadalupe García-López, Anayansí Molina-Hernández, Oscar Flores-Herrera, Francisco J Zavala-Díaz de la Serna, María Del Rosario Peralta-Pérez, Héctor Flores-Herrera
It is estimated that 15% of all newborns admitted to the neonatal intensive care unit (NICU) for suspected sepsis receive multiple broad-spectrum antibiotics without pathogen identification. The gold standard for bacterial sepsis detection is blood culture, but the sensitivity of this method is very low. Recently, amplification and analysis of the 16S ribosomal DNA (rDNA) bacterial gene in combination with denaturing gradient gel electrophoresis (DGGE) has proven to be a useful approach for identifying bacteria that are difficult to isolate by standard culture methods...
October 31, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29080051/reducing-unnecessary-chest-x-rays-antibiotics-and-bronchodilators-through-implementation-of-the-nice-bronchiolitis-guideline
#13
Richard Breakell, Benjamin Thorndyke, Julie Clennett, Christian Harkensee
Chest X-rays (CXR), antibiotics and inhaled/nebulized therapy are overused in bronchiolitis, despite evidence-based guidelines suggesting supportive management only. This study investigates the effect of the implementation of the NICE bronchiolitis guideline in a secondary paediatric unit in England. We present a quality improvement project with a completed audit cycle (winter 2014-2015 and 2015-2016) pre- and post-implementation of the NICE bronchiolitis guideline. The educational intervention included sessions for raising awareness of appropriate and inappropriate management of bronchiolitis for both clinicians and nursing staff...
October 28, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29063960/neurodevelopmental-outcome-in-survivors-of-hypoxic-ischemic-encephalopathy-without-cerebral-palsy
#14
Breda C Hayes, Elaine Doherty, Andrea Grehan, Cathy Madigan, Cliona McGarvey, Siobhan Mulvany, Tom G Matthews, Mary D King
To access outcome following hypoxic ischemic encephalopathy (HIE), survivors without cerebral palsy were invited for formal developmental assessment. Children aged ≥ 42 months were assessed using the NEPSY-2, Movement Assessment Battery for Children 2 (Movement ABC-2), Behavior Rating Inventory of Executive Function, and the Child Behavior Checklist. Children aged < 42 months were assessed using the Bayley Scales of Infant and Toddler Development, Third Edition (BSITD-3). One hundred forty-six children attended for assessments [Grade 1 (112), Grade 2 (33), and Grade 3 (1)]...
October 24, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29063210/late-onset-sepsis-due-to-urinary-tract-infection-in-very-preterm-neonates-is-not-uncommon
#15
Alexander B Mohseny, Veerle van Velze, Sylke J Steggerda, Vivianne E H J Smits-Wintjens, Vincent Bekker, Enrico Lopriore
Urinary tract infection (UTI) is a common cause of sepsis in infants. Premature infants hospitalized at a neonatal intensive care unit often have risk factors for infection. In this group, the risk of UTI is not clearly known, and guidelines for urine analysis are not unanimous. We aimed to identify the risk of UTI in premature infants with central lines, suspected of late-onset sepsis. We analyzed all 1402 infants admitted to our hospital between 2006 and 2014 with a gestational age less than 32 weeks. Six hundred sixty-two episodes of sepsis evaluations were found with an unknown source of infection based on clinical symptoms...
October 23, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29063209/interrelationship-between-iodine-nutritional-status-of-lactating-mothers-and-their-absolutely-breast-fed-infants-in%C3%A2-coastal%C3%A2-districts-of%C3%A2-gangetic%C3%A2-west-bengal-in-india
#16
N Pal, S K Samanta, A Chakraborty, N K Chandra, A K Chandra
Iodine nutritional status of 128 lactating mothers and their breast-fed infants (1-3 months) from iodine-replete villages during post-salt iodization period was evaluated. Mothers' urine, blood, and breast milk (BM) and infants' urine and blood were collected and analyzed for iodine and serum FT4 and TSH estimation. Mothers' and infants' age, parity, occupation, education, and household income were recorded. Median urinary iodine concentration (UIC) of infants was 250 μg/L, indicating their iodine intake was more than adequate...
October 23, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29022080/urinary-potassium-to-urinary-potassium-plus-sodium-ratio-can-accurately-identify-hypovolemia-in-nephrotic-syndrome-a-provisional-study
#17
Werner Keenswijk, Mohamad Ikram Ilias, Ann Raes, Raymond Donckerwolcke, Johan Vande Walle
There is evidence pointing to a decrease of the glomerular filtration rate (GFR) in a subgroup of nephrotic children, likely secondary to hypovolemia. The aim of this study is to validate the use of urinary potassium to the sum of potassium plus sodium ratio (UK/UK+UNa) as an indicator of hypovolemia in nephrotic syndrome, enabling detection of those patients who will benefit from albumin infusion. We prospectively studied 44 nephrotic children and compared different parameters to a control group (36 children)...
October 11, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28975428/a-new-efficient-method-to-monitor-precocious-puberty-nationwide-in-france
#18
Annabel Rigou, Joëlle Le Moal, Juliane Léger, Alain Le Tertre, Jean-Claude Carel
Clinical precocious puberty (PP) is a disease, reputed to be on the increase and suspected to be linked to endocrine disrupting chemicals (EDC) exposure. Population-based epidemiological data are lacking in France and scarce elsewhere. We accessed the feasibility of monitoring PP nationwide in France in this context, using a nationwide existing database, the French National Health Insurance Information System. Here, we present the method we used with a step-by-step approach to build and select the most suitable indicator...
October 3, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28963679/clinical-practice-nausea-and-vomiting-in-acute-gastroenteritis-physiopathology-and-management
#19
REVIEW
Beatrice C Canziani, Peter Uestuener, Emilio F Fossali, Sebastiano A G Lava, Mario G Bianchetti, Carlo Agostoni, Gregorio P Milani
Currently recommended management of acute gastroenteritis is supportive. Although the affected children habitually have vomiting, recommendations do not focus on the correction of this symptom. In this condition, elevated ketone bodies and stimuli initiated by gut mucosa damage produced by the enteral pathogen likely underlay nausea and vomiting. As compared to 0.9% saline, intravenous administration of a dextrose-containing bolus of 0.9% saline is associated with a greater reduction of circulating ketones and a shorter duration of nausea and vomiting...
September 30, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28963630/the-spectrum-of-care-for-pediatric-refugees-and-asylum-seekers-at-a-tertiary-health-care-facility-in-switzerland-in-2015
#20
Christian Pohl, Ines Mack, Torsten Schmitz, Nicole Ritz
The aim of this retrospective study was to describe the epidemiology and spectrum of infections of admitted pediatric refugees and asylum seekers in a tertiary referral hospital in a high-income country in Europe. We identified recent refugees and asylum seekers < 18 years of age admitted to the University Children's Hospital in Basel, Switzerland, in 2015. A retrospective analysis was performed using electronic patient records. We identified 105 admissions in 93 patients with a median age of 5.7 (IQR 2...
September 30, 2017: European Journal of Pediatrics
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