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Chinese Medical Journal

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https://www.readbyqxmd.com/read/29848837/pharmacokinetic-studies-of-factor-viii-in-chinese-boys-with-severe-hemophilia-a-a-single-center-study
#1
Zhen-Ping Chen, Pei-Jing Li, Gang Li, Ling Tang, Ying-Zi Zhen, Xin-Yi Wu, Xiao-Ling Cheng, Koon Hung Luke, Victor S Blanchette, Man-Chiu Poon, Qiu-Lan Ding, Run-Hui Wu
Background: Although much attention has been paid to the pharmacokinetics (PKs) of different factor VIII (FVIII) concentrates in persons with hemophilia A (HA), limited information is available in young boys with severe HA. In this study, we aimed to assess the PK parameters of FVIII products in boys with severe HA in China. Methods: A total of 36 boys (plasma-derived [pd]-FVIII, n = 15; recombinant [r] FVIII, n = 21) were enrolled between January 2015 and May 2016 in Beijing Children's Hospital...
May 30, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998906/corrigendum-genistein-improves-liver-damage-in-male-mice-exposed-to-morphine
#2
(no author information available yet)
[This corrects the article DOI: 10.4103/0366-6999.235117].
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998905/diagnosis-related-groups-payment-reform-in-beijing
#3
LETTER
Wei-Ping Jiao
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998904/acquired-syphilis-in-a-chinese-family-among-three-generations
#4
LETTER
Fu-Quan Long, Li-Shi Zhao, Jia Chen
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998903/influence-of-the-anatomy-of-the-collecting-system-upon-percutaneous-nephrolithotomy-for-removal-of-renal-staghorn-stones
#5
LETTER
Bo Xiao, Xiao-Lin Diao, Wei-Guo Hu, Xin Zhang, Song Chen, Yu-Bao Liu, Yu-Zhe Tang, Wen-Jie Bai, Jian-Xing Li
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998902/hybrid-management-for-supraceliac-aortic-aneurysm-in-a-high-risk-patient
#6
LETTER
Jun Seong Kwon, Jeong Kye Hwang, Sun Cheol Park, Sang Dong Kim
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998901/acute-pancreatitis-as-a-long-term-complication-of-pancreatectomy
#7
LETTER
Dong-Ya Huang, Qiang Li, Feng Guo, Kui-Rong Jiang, Cun-Cai Dai, Jun-Li Wu, Wen-Tao Gao, Yi Miao
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998900/successful-management-of-a-rare-case-of-humerus-non-hodgkin-s-lymphoma-in-rapid-progress
#8
LETTER
Shu-Zhong Liu, Xi Zhou, An Song, Yi-Peng Wang, Yong Liu
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998899/effect-of-education-by-messaging-software-on-the-quality-of-bowel-preparation-for-colonoscopy
#9
LETTER
Qing-Xia Zhang, Jie Li, Qin Zhang, Yi Li, Cong-Han Lei, Bai-Xue Shang, Xiao-Shuang Guan, Qing Zhang
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998898/reverse-postulation-for-disruption-of-brain-networks-hypothesis-of-schizophrenia
#10
LETTER
Xin-Yu Guo, Shen Li, Hong-Jun Tian, Jie Li, Chuan-Jun Zhuo
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998897/successful-treatment-of-erlotinib-on-metastatic-adenoid-cystic-carcinoma-of-the-lacrimal-gland
#11
LETTER
Ke-Ke Nie, Jing Xu, Chen Gao, Zhong-Fa Zhang, Ke-Tao Lan, You-Xin Ji
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998896/unilateral-isolated-basal-vein-thrombosis-associated-with-deep-cerebral-venous-infarction
#12
LETTER
Min-Jian Qiu, Jun Tian, Wei Luo, Bao-Rong Zhang
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998895/ten-things-to-be-considered-in-practicing-critical-care-echocardiography
#13
Xin Ding, Da-Wei Liu, Yan-Gong Cao, Hong-Min Zhang, Huan Chen, Hua Zhao, Xiao-Ting Wang
No abstract text is available yet for this article.
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998894/pulmonary-embolism-in-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease
#14
REVIEW
Yao-Qian Cao, Li-Xia Dong, Jie Cao
Objective: In most countries, nearly 6% of the adults are suffering from chronic obstructive pulmonary disease (COPD), which puts a huge economic burden on the society. Moreover, COPD has been considered as an independent risk factor for pulmonary embolism (PE). In this review, we summarized the existing evidence that demonstrates the associations between COPD exacerbation and PE from various aspects, including epidemiology, pathophysiological changes, risk factors, clinical features, management, and prognosis...
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998893/effects-of-dandelion-extract-on-the-proliferation-of-rat-skeletal-muscle-cells-and-the-inhibition-of-a-lipopolysaccharide-induced-inflammatory-reaction
#15
Qiang Liu, Heng Zhao, Yue Gao, Yan Meng, Xiang-Xuan Zhao, Shi-Nong Pan
Background: Dandelion is commonly used in traditional Chinese medicine with several active compounds found in extracts. It has a variety of pharmacological effects, such as a reduction in swelling and inflammation, and detoxification. The mechanism by which dandelion extract inhibits the inflammatory response in skeletal muscle cells remains unknown; therefore, the aim of this study was to investigate the effects of dandelion extract root on the proliferation of skeletal muscle cells and the alleviation of lipopolysaccharide (LPS)-induced inflammatory response in vitro...
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998892/inhibitory-effects-of-sulfur-dioxide-on-rat-myocardial-fibroblast-proliferation-and-migration
#16
Lu-Lu Zhang, Jun-Bao Du, Chao-Shu Tang, Hong-Fang Jin, Ya-Qian Huang
Background: Myocardial fibrosis is an important pathological change in many heart diseases, but its pathogenesis is very complex and has not yet been fully elucidated. The study was designed to examine whether endogenous sulfur dioxide (SO2 ) is a novel myocardial fibroblast proliferation and migration inhibitor. Methods: Primary rat myocardial fibroblasts were isolated and transfected with aspartate aminotransferase (AAT1 and AAT2) knockdown lentivirus or empty lentivirus...
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998891/constructing-a-novel-three-dimensional-biomimetic-corneal-endothelium-graft-by-culturing-corneal-endothelium-cells-on-compressed-collagen-gels
#17
Yu-Jie Cen, Yun Feng
Background: Endothelium allotransplantation is the primary treatment for corneal decompensation. The worldwide shortage of donor corneal tissue has led to increasing pressure to seek an alternative for surgical restoration of corneal endothelium. Compressed collagen (CC) gels have excellent biocompatibility, simple preparation course and easy to be manipulated. This study aimed to form a new biomimetic endothelium graft by CC. Methods: We expanded bovine corneal endothelial cells (B-CECs) on laminin-coated CC to form a biomimetic endothelium graft...
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998890/effect-of-autophagy-inhibition-on-the-protection-of-ischemia-preconditioning-against-myocardial-ischemia-reperfusion-injury-in-diabetic-rats
#18
Ya-Yang Liu, Chao Sun, Fu-Shan Xue, Gui-Zhen Yang, Hui-Xian Li, Qing Liu, Xu Liao
Background: Ischemia preconditioning (IPC) remains the most powerful intervention of protection against myocardial ischemia/reperfusion injury (IRI), but diabetes can weaken or eliminate its cardioprotective effect and detailed mechanisms remain unclear. In this study, we aimed to explore whether changes of autophagy in the diabetic condition are attributable to the decreased cardioprotective effect of IPC. Methods: Sixty diabetic male Sprague-Dawley rats were randomly divided into the control (C), IRI, rapamycin (R), wortmannin (W), rapamycin + IPC (R + IPC), and wortmannin + IPC (W + IPC) groups...
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998889/effect-of-dandelion-extracts-on-the-proliferation-of-ovarian-granulosa-cells-and-expression-of-hormone-receptors
#19
Tong Wang, Bing Xue, Hui Shao, Shu-Yu Wang, Li Bai, Cheng-Hong Yin, Huan-Ying Zhao, Yong-Chao Qi, Le-Le Cui, Xin He, Yan-Min Ma
Background: In the current society, infertility related to age has become a social problem. The in vitro fertilization (IVF) success rate in women with poor ovarian response (POR) is very low. Dandelion extract T-1 (DE-T1) is an effective component of the extract from the leaves and stems of Taraxacum officinale, which is one of the medicines used in some patients with POR, but its molecular mechanism remains unclear. Methods: Following IVF, ovarian granulosa cells (GCs) of sixty patients were extracted and divided into normal ovarian response (NOR) and POR groups...
July 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29998888/curcumin-inhibits-lipopolysaccharide-induced-mucin-5ac-hypersecretion-and-airway-inflammation-via-nuclear-factor-erythroid-2-related-factor-2
#20
Xiao-Ping Lin, Cheng Xue, Jia-Min Zhang, Wei-Jing Wu, Xiao-Yang Chen, Yi-Ming Zeng
Background: Excess mucus production is an important pathophysiological feature of chronic inflammatory airway diseases. Effective therapies are currently lacking. The aim of the study was to evaluate the effects of curcumin (CUR) on lipopolysaccharide (LPS)-induced mucus secretion and inflammation, and explored the underlying mechanism in vivo and in vitro. Methods: For the in vitro study, human bronchial epithelial (NCI-H292) cells were pretreated with CUR or vehicle for 30 min, and then exposed to LPS for 24 h...
July 20, 2018: Chinese Medical Journal
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