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Chinese Medical Journal

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https://www.readbyqxmd.com/read/30381583/impact-of-cyp3a4-1g-polymorphism-on-fentanyl-analgesia-assessed-by-analgesia-nociception-index-in-chinese-patients-undergoing-hysteroscopy
#1
Qi Yan, Yi Su, Lan Gao, Nan Ding, Hong-Ying Zhang, Wen E, Yue Wang, Yi Feng, Hai-Yan An
Background: The clinical efficacy of fentanyl for pain control differs greatly across individuals. The purpose of this study was to investigate the impact of CYP3A4*1G polymorphism including wild-type homozygote (CYP3A4*1/*1, GG), mutant heterozygote (CYP3A4*1/*1G, GA), and mutant homozygote (CYP3A4*1G/*1G, AA) on fentanyl analgesia in Chinese patients undergoing hysteroscopy by the assessment of analgesia nociception index (ANI). Methods: A total of 200 gynecologic patients scheduled for elective hysteroscopy under general anesthesia at Peking University People's Hospital from May to December in 2017 were enrolled in this study...
October 24, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425211/renal-fibrosis-and-mitochondrial-damage
#2
Jiao Qin, Zhang-Zhe Peng, Qian Li, Rui Wen, Li-Jian Tao
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425210/stenting-for-aorto-ostial-in-stent-restenosis-via-side-strut-of-an-excessively-protruding-stent-guided-by-intracoronary-imaging
#3
LETTER
Yu Du, Ying-Xin Zhao, Wei Liu, Jian-Wei Zhang, Zhen-Xian Yan, Yu-Jie Zhou
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425209/severe-lymphopenia-and-related-t-cell-immunity-in-an-avian-influenza-a-h7n9-infected-patient
#4
LETTER
Nan-Nan Zhang, Yi Zhang, Jin-Gen Xia, Min Li, Xu Huang, Ruo-Yang Zhang, Qing-Yuan Zhan
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425208/evaluation-of-the-spasticity-after-botulinum-toxin-injection-using-paired-pulse-transcranial-magnetic-stimulation
#5
LETTER
Chin-Hsuan Chia, Fang Li, Qin-Ying Li, Wen-Ting Qin
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425207/cardiac-resynchronization-therapy-pacemaker-implantation-guided-by-three-dimensional-electroanatomic-mapping-for-a-chinese-young-man-with-danon-disease
#6
LETTER
Lan-Yan Guo, Bo Wang, Min Shen, Bing Liu, Li-Wen Liu
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425206/a-rare-cause-of-recurrent-fatal-hemoptysis-dieulafoy-s-disease-of-the-bronchus
#7
LETTER
Feng Wang, Tu-Guang Kuang, Jian-Feng Wang, Yuan-Hua Yang
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425205/mining-and-correlation-analysis-of-association-rules-between-properties-and-therapeutic-efficacy-of-chinese-materia-medica-based-on-strategy-pattern
#8
LETTER
Di-Yao Wu, Xin-You Zhang, Xiao-Ling Zhou
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425204/prevalence-of-chronic-kidney-disease-mineral-bone-disorder-in-hemodialysis-patients-in-hebei-china
#9
LETTER
Jing-Jing Jin, Sheng-Lei Zhang, Jin-Sheng Xu, Li-Wen Cui, Hui-Ran Zhang, Ya-Ling Bai
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425203/a-case-of-podocytic-infolding-glomerulopathy-with-primary-sj%C3%A3-gren-s-syndrome-and-hashimoto-s-thyroiditis
#10
LETTER
Jun-Yan Fang, A-Hui Song, Bo Shen, Ying-Li Liu
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425202/serum-metabolic-profiling-in-a-mouse-model-of-adriamycin-induced-focal-segmental-glomerulosclerosis
#11
LETTER
Li Lyu, Cai-Li Wang, Zeng-Yan Li, Ying-Jin Shi, Yan-Hui Zhang, Yan Mi, Zhao Hu
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425201/statistical-prediction-in-pathological-types-of-chronic-kidney-disease
#12
LETTER
Mei-Fang Song, Zong-Wei Yi, Xue-Jing Zhu, Xue-Ling Qu, Chang Wang, Zai-Qi Zhang, Lin Sun, Fu-You Liu, Yuan Yang
No abstract text is available yet for this article.
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425200/-helicobacter-pylori-infection-is-associated-with-occurrence-of-proteinuria-in-type-2-diabetes-patients-a-systemic-review-and-meta-analysis
#13
Yan Shi, Jia-Yu Duan, Dong-Wei Liu, Ying-Jin Qiao, Qiu-Xia Han, Shao-Kang Pan, Li Tang, Guang-Yan Cai, Xiang-Mei Chen, Zhang-Suo Liu, Han-Yu Zhu
Background: Type 2 diabetes (T2DM) patients are susceptible to Helicobacter pylori (HP), and it has been reported that the occurrence of proteinuria is associated with HP infection in T2DM patients; however, this view remains controversial. This meta-analysis aimed to explore the association between HP infection and the occurrence of proteinuria in T2DM patients. In addition, we hope to provide some recommendations to readers in clinical or related fields. Methods: Our meta-analysis was conducted with the methodology of the Cochrane Collaboration...
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425199/effect-of-endothelial-microparticles-induced-by-hypoxia-on-migration-and-angiogenesis-of-human-umbilical-vein-endothelial-cells-by-delivering-microrna-19b
#14
Hui-Zhu Liang, Su-Fang Li, Feng Zhang, Man-Yan Wu, Chang-Long Li, Jun-Xian Song, Chongyou Lee, Hong Chen
Background: Microparticles (MPs) are small extracellular plasma membrane particles shed by activated and apoptotic cells, which are involved in the development of atherosclerosis. Our previous study found that microRNA (miR)-19b encapsulated within endothelial MPs (EMPs) may contribute to the upregulation of circulating miR-19b in unstable angina patients. Hypoxia is involved in atherosclerosis as a critical pathological stimulus. However, it still remains unclear whether the increase of miR-19b levels in EMPs is related to hypoxia and if the effect of miR-19b - wrapped within EMPs - stimulates hypoxia on vascular endothelial cells...
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425198/purinergic-2x7-receptor-is-involved-in-the-podocyte-damage-of-obesity-related-glomerulopathy-via-activating-nucleotide-binding-and-oligomerization-domain-like-receptor-protein-3-inflammasome
#15
Xiao-Xia Hou, Hong-Rui Dong, Li-Jun Sun, Min Yang, Hong Cheng, Yi-Pu Chen
Background: The nucleotide-binding and oligomerization domain-like receptor protein 3 (NLRP3) inflammasome composed of NLRP3, apoptosis-associated speck-like protein containing CARD (ASC), and caspase-1 is engaged in the inflammatory response of many kidney diseases and can be activated by purinergic 2X7 receptor (P2X7R). This study was conducted to explore whether P2X7R plays a pathogenic role in the podocyte damage of obesity-related glomerulopathy (ORG) and whether this role is mediated by the activation of NLRP3 inflammasome...
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425197/clinical-neuroimaging-and-pathological-analyses-of-13-chinese-leigh-syndrome-patients-with-mitochondrial-dna-mutations
#16
Xiao-Lin Yu, Chuan-Zhu Yan, Kun-Qian Ji, Peng-Fei Lin, Xue-Bi Xu, Ting-Jun Dai, Wei Li, Yu-Ying Zhao
Background: Leigh syndrome (LS) is a rare disease caused by mitochondrial defects and has high phenotypic and genotypic heterogeneity. We analyzed the clinical symptoms, neuroimaging, muscular histopathology, and genotypes of 13 Chinese LS patients with mitochondrial DNA (mtDNA) mutations. Methods: Mutations in mtDNA were identified by targeted sequencing. The brain imaging features on magnetic resonance imaging (MRI) were analyzed. The levels of lactate in fasting blood and cerebrospinal fluid (CSF) were routinely tested...
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425196/validation-of-predictive-value-of-patterns-of-nonadherence-to-antiplatelet-regimen-in-stented-patients-thrombotic-risk-score-in-chinese-population-undergoing-percutaneous-coronary-intervention-a-prospective-observational-study
#17
Xue-Yan Zhao, Jian-Xin Li, Xiao-Fang Tang, Jing-Jing Xu, Ying Song, Lin Jiang, Jue Chen, Lei Song, Li-Jian Gao, Zhan Gao, Shu-Bin Qiao, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan
Background: The patterns of nonadherence to antiplatelet regimen in stented patients (PARIS) thrombotic risk score are a novel score for predicting the risk of coronary thrombotic events (CTEs) after percutaneous coronary intervention (PCI) with drug-eluting stents. However, the prognostic value of this score has not been fully evaluated in non-Euro-American PCI populations. Methods: We performed a prospective, observational study of 10,724 patients who underwent PCI in Fuwai hospital, China and evaluated the PARIS thrombotic risk score's predictive value of CTEs in the PCI population...
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425195/efficacy-and-safety-of-tofacitinib-in-chinese-patients-with-rheumatoid-arthritis
#18
Zhan-Guo Li, Yi Liu, Hu-Ji Xu, Zhi-Wei Chen, Chun-De Bao, Jie-Ruo Gu, Dong-Bao Zhao, Yuan An, Lie-Ju Hwang, Lisy Wang, Joel Kremer, Qi-Zhe Wu
Background: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This study assessed the efficacy and safety of tofacitinib in Chinese patients with RA enrolled in Phase 3 and long-term extension (LTE) studies. Methods: ORAL Sync was a 1-year, randomized, placebo-controlled, Phase 3 trial. Patients received tofacitinib 5 or 10 mg twice daily (BID) or placebo advanced to tofacitinib 5 or 10 mg BID at 3 or 6 months. All patients remained on ≥1 background conventional synthetic disease-modifying antirheumatic drug...
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425194/beneficial-effect-of-moderately-increasing-hypothermic-machine-perfusion-pressure-on-donor-after-cardiac-death-renal-transplantation
#19
Chen-Guang Ding, Pu-Xun Tian, Xiao-Ming Ding, He-Li Xiang, Yang Li, Xiao-Hui Tian, Feng Han, Qian-Hui Tai, Qian-Long Liu, Jin Zheng, Wu-Jun Xue
Background: Vascular resistance and flow rate during hypothermic machine perfusion (HMP) of kidneys is correlated with graft function. We aimed to determine the effects of increasing HMP pressure versus maintaining the initial pressure on kidney transplantation outcomes. Methods: We retrospectively reviewed the data of 76 primary transplantation patients who received HMP-preserved kidneys from 48 donors after cardiac death between September 1, 2013, and August 31, 2015...
November 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30425193/new-mutation-of-coenzyme-q-10-monooxygenase-6-causing-podocyte-injury-in-a-focal-segmental-glomerulosclerosis-patient
#20
Cheng-Cheng Song, Quan Hong, Xiao-Dong Geng, Xu Wang, Shu-Qiang Wang, Shao-Yuan Cui, Man-Di Guo, Ou Li, Guang-Yan Cai, Xiang-Mei Chen, Di Wu
Background: Focal segmental glomerulosclerosis (FSGS) is a kidney disease that is commonly associated with proteinuria and the progressive loss of renal function, which is characterized by podocyte injury and the depletion and collapse of glomerular capillary segments. The pathogenesis of FSGS has not been completely elucidated; however, recent advances in molecular genetics have provided increasing evidence that podocyte structural and functional disruption is central to FSGS pathogenesis...
November 20, 2018: Chinese Medical Journal
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