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Chinese Medical Journal

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https://www.readbyqxmd.com/read/28397736/bleeding-from-the-liver-capsule-when-to-perform-surgery
#1
LETTER
Meng-Yao Luo, Zhong Jia, Yang Cai, Ya-Feng Wan
No abstract text is available yet for this article.
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397735/acute-pulmonary-embolism-after-radiofrequency-catheter-ablation
#2
LETTER
Lan-Yan Guo, Zhong-Chan Sun, Dian-Xin Zhang, Bing Liu
No abstract text is available yet for this article.
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397734/mixed-dubin-gilbert-syndrome-a-compound-heterozygous-phenotype-of-two-novel-variants-in-abcc2-gene
#3
Jun Jiang, Hua-Gui Wang, Wei-Li Wu, Xiang-Xin Peng
No abstract text is available yet for this article.
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397733/what-has-shaken-the-determination-of-medical-students-to-become-a-doctor
#4
Xin-Ye Xu, Wei Gao, Ai-Jing Zhang, Jing Huang, Ming Cui, Wei Zhao
No abstract text is available yet for this article.
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397732/a-curriculum-using-simulation-models-to-teach-gynecology-and-obstetrics-to-trainees
#5
He-Ya Ren, Zhi-Jing Sun, Lan Zhu, Jing-He Lang, Hui Pan, Xia Wu
No abstract text is available yet for this article.
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397731/postrandomization-confounding-challenges-the-applicability-of-randomized-clinical-trials-in-comparative-effectiveness-research
#6
Ya-Guang Peng, Xiao-Lu Nie, Jing-Jing Feng, Xiao-Xia Peng
No abstract text is available yet for this article.
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397730/programmed-cell-death-1-programmed-death-ligand-1-pathway-a-new-target-for-sepsis
#7
REVIEW
Qiang Liu, Chun-Sheng Li
OBJECTIVE: Sepsis remains a leading cause of death in many Intensive Care Units worldwide. Immunosuppression has been a primary focus of sepsis research as a key pathophysiological mechanism. Given the important role of the negative costimulatory molecules programmed cell death-1 (PD-1) and programmed death-ligand 1 (PD-L1) in the occurrence of immunosuppression during sepsis, we reviewed literatures related to the PD-1/PD-L1 pathway to examine its potential as a new target for sepsis treatment...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397729/glutathione-s-transferase-p1-ile105val-polymorphism-and-male-infertility-risk-an-updated-meta-analysis
#8
Xue-Kun Huang, Yong-Han Huang, Juan-Hua Huang, Jing-Yao Liang
BACKGROUND: Several studies concerning the association between glutathione S-transferase P1 (GSTP1) Ile105Val polymorphism and male infertility risk have reported controversial findings. The present study was aimed to explore this association using a meta-analysis. METHODS: The PubMed, EMBASE, China National Knowledge Infrastructure (CNKI), and Wanfang databases were searched. Odds ratios (OR s) with 95% confidence intervals (CI s) were calculated to estimate the strength of the association...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397728/recommendations-on-the-clinical-use-of-compound-danshen-dripping-pills
#9
(no author information available yet)
No abstract text is available yet for this article.
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397727/neutralization-of-interleukin-9-decreasing-mast-cells-infiltration-in-experimental-autoimmune-encephalomyelitis
#10
Jun-Jie Yin, Xue-Qiang Hu, Zhi-Feng Mao, Jian Bao, Wei Qiu, Zheng-Qi Lu, Hao-Tian Wu, Xiao-Nan Zhong
BACKGROUND: Th9 cells are a newly discovered CD4+ T helper cell subtype, characterized by high interleukin (IL)-9 secretion. Growing evidences suggest that Th9 cells are involved in the pathogenic mechanism of multiple sclerosis (MS). Mast cells are multifunctional innate immune cells, which are perhaps best known for their role as dominant effector cells in allergies and asthma. Several lines of evidence point to an important role for mast cells in MS and its animal models. Simultaneously, there is dynamic "cross-talk" between Th9 and mast cells...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397726/long-term-brain-tissue-monitoring-after-semi-brain-irradiation-in-rats-using-proton-magnetic-resonance-spectroscopy-a-preliminary-study-in-vivo
#11
Hong Chen, Yu-Shu Cheng, Zheng-Rong Zhou
BACKGROUND: In head and neck neoplasm survivors treated with brain irradiation, metabolic alterations would occur in the radiation-induced injury area. The mechanism of these metabolic alterations has not been fully understood, while the alternations could be sensitively detected by proton (1H) nuclear magnetic resonance spectroscopy (MRS). In this study, we investigated the metabolic characteristics of radiation-induced brain injury through a long-term follow-up after radiation treatment using MRS in vivo...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397725/transforming-growth-factor-beta-1-involved-in-the-pathogenesis-of-endometriosis-through-regulating-expression-of-vascular-endothelial-growth-factor-under-hypoxia
#12
Yue-Xin Yu, Yin-Ling Xiu, Xi Chen, Ya-Li Li
BACKGROUND: Endometriosis (EMs) is a common gynecological disorder characterized by endometrial-like tissue outside the uterus. Hypoxia induces the expression of many important downstream genes to regulate the implantation, survival, and maintenance of ectopic endometriotic lesions. Transforming growth factor-beta 1 (TGF-β1) plays a major role in the etiology of EMs. We aimed to determine whether TGF-β1 affects EMs development and progression and its related mechanisms in hypoxic conditions...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397724/drug-reaction-with-eosinophilia-and-systemic-symptoms-retrospective-analysis-of-104-cases-over-one-decade
#13
Li Wang, Xue-Ling Mei
BACKGROUND: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe, life-threatening disorder caused by drugs. In the present study, we tried to explore the types of DRESS-inducing drugs, incubation period, features of skin rashes, accompanying visceral damage, and effectiveness of glucocorticoid therapy so as to inform clinical practice. METHODS: Patients diagnosed with a drug-induced rash, dermatitis, and DRESS admitted to our hospital from January 2006 to December 2015 were included in the study...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397723/short-term-preoperative-octreotide-for-thyrotropin-secreting-pituitary-adenoma
#14
Hong-Juan Fang, Yu Fu, Huan-Wen Wu, Yi-Lin Sun, Yang-Fang Li, Ya-Zhuo Zhang, Li-Yong Zhong
BACKGROUND: Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare cause of hyperthyroidism. Somatostatin (SST) analogs work by interacting with somatostatin receptors (SSTRs). This study aimed to evaluate short-term preoperative octreotide (OCT) use in TSHoma patients and to investigate SSTR2 and SSTR5 expression and observe structural changes in tumor tissue. METHODS: We reviewed records and samples from eight TSHoma patients treated between July 2012 and July 2015...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397722/long-term-outcomes-of-primary-percutaneous-coronary-intervention-with-second-generation-drug-eluting-stents-in-st-elevation-myocardial-infarction-patients-caused-by-very-late-stent-thrombosis
#15
Chen He, Yuan-Liang Ma, Chuang-Shi Wang, Lin Jiang, Jia-Hui Zhang, Yi Yao, Xiao-Fang Tang, Bo Xu, Run-Lin Gao, Jin-Qing Yuan
BACKGROUND: The ST-segment elevation myocardial infarction (STEMI) patients due to stent thrombosis (ST) remain a therapeutic challenge for a clinician. Till date, very few researches have been conducted regarding the safety and effectiveness of primary percutaneous coronary intervention (PCI) with second-generation drug-eluting stents (DES) for STEMI caused by very late ST (VLST). This retrospective study evaluated the safety, efficacy, and outcomes of primary PCI with second-generation DES for STEMI due to VLST compared with primary PCI for STEMI due to de novo lesion...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397721/ultrasonographic-characteristics-of-cortical-sulcus-development-in-the-human-fetus-between-18-and-41-weeks-of-gestation
#16
Xi Chen, Sheng-Li Li, Guo-Yang Luo, Errol R Norwitz, Shu-Yuan Ouyang, Hua-Xuan Wen, Ying Yuan, Xiao-Xian Tian, Jia-Min He
BACKGROUND: Fetal brain development is a complicated process that continues throughout pregnancy. Fetal sulcus development has typical morphological features. Assessment of fetal sulcus development to understand the cortical maturation and development by prenatal ultrasound has become widespread. This study aimed to explore a reliable method to assess cortical sulcus and to describe the normal sonographic features of cortical sulcus development in the human fetus between 18 and 41 weeks of gestation...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397720/efficacy-and-safety-of-tenofovir-disoproxil-treatment-for-chronic-hepatitis-b-patients-with-genotypic-resistance-to-other-nucleoside-analogues-a-prospective-study
#17
Jing Zhou, Yue-Ying Liu, Jiang-Shan Lian, Li-Fang Pan, Jian-Le Yang, Jian-Rong Huang
BACKGROUND: Tenofovir disoproxil (TDF) is a promising salvage therapy for patients with chronic hepatitis B (CHB) who failed regimens of other nucleoside analogues (NAs). In this study, we aimed to investigate the clinical efficacy and safety of TDF monotherapy in Chinese CHB patients with genotypic resistance. METHODS: A total of 33 CHB patients who had failed treatment with other NAs and had genotypic resistance were switched to TDF monotherapy for 48 weeks. Patients' demographic data (age, sex, history of hepatitis B virus [HBV] therapy), laboratory testing results (hepatitis B e antigen [HBeAg] status, HBV DNA levels, alanine aminotransferase [ALT] levels, serum creatinine, urinary protein, genotypic assay), clinical symptoms, and liver color ultrasound examinations were collected for evaluation at day 0 (baseline) and the 12th, 24th, 36th, and 48th weeks after initiating treatment...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397719/toll-like-receptor-4-signaling-pathway-in-the-protective-effect-of-pioglitazone-on-experimental-immunoglobulin-a-nephropathy
#18
Jia-Nan Zou, Jing Xiao, Sha-Sha Hu, Chen-Sheng Fu, Xiao-Li Zhang, Zhen-Xing Zhang, Yi-Jun Lu, Wei-Jun Chen, Zhi-Bin Ye
BACKGROUND: In vitro experiments have revealed that toll-like receptor 4 (TLR4) pathway is involved in the progression of immunoglobulin A nephropathy (IgAN) by induction of proinflammatory cytokines. Evidence showed that, in other disease models, peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists have been shown to exert anti-inflammatory effects through suppression of the expression and activity of TLR4. However, the interaction between PPAR-γ and TLR4 in IgAN has not been fully studied both in vitro and in vivo...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397718/clinical-predictors-of-outcome-in-patients-with-anti-neutrophil-cytoplasmic-autoantibody-related-renal-vasculitis-experiences-from-a-single-center
#19
Lei Pu, Gui-Sen Li, Yu-Rong Zou, Ping Zhang, Li Wang
BACKGROUND: Primary anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a chronic autoimmune disease associated with multisystem dysfunction. Renal involvement is common and closely associated with outcome. The purpose of this study was to investigate the clinical determinants of mortality of patients with AAV-related renal injury in the first 2 years after diagnosis in a single West Chinese center. METHODS: Demographic and laboratory parameters of 123 consecutive patients with AAV-related renal injury diagnosed in Renal Division and Institute of Nephrology, Sichuan Provincial People's Hospital between 2004 and 2012 were collected retrospectively...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28397717/renal-phospholipase-a2-receptor-and-the-clinical-features-of-idiopathic-membranous-nephropathy
#20
Ning-Xin Xu, Qiong-Hong Xie, Zhu-Xing Sun, Jia Wang, Yan Li, Liang Wang, Shao-Jun Liu, Jun Xue, Chuan-Ming Hao
BACKGROUND: According to the renal phospholipase A2 receptor (PLA2R) immunohistochemistry, idiopathic membranous nephropathy (iMN) could be categorized into PLA2R-associated and non-PLA2R-associated iMN. This study aimed to examine whether the non-PLA2R-associated iMN had any difference in clinical features compared with PLA2R-associated iMN. METHODS: A total of 231 adult patients diagnosed as iMN were recruited to this retrospective study. Renal PLA2R expression was examined by immunofluorescence...
April 20, 2017: Chinese Medical Journal
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