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Drug and Alcohol Dependence

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https://www.readbyqxmd.com/read/28918240/contingency-management-treatment-in-cocaine-using-methadone-maintained-patients-with-and-without-legal-problems
#1
Meredith K Ginley, Carla J Rash, Todd A Olmstead, Nancy M Petry
BACKGROUND: Legal difficulties and cocaine use are prevalent in methadone maintenance patients, and they are related to one another, as well as to poor response to methadone treatment. Contingency management (CM) is efficacious for decreasing cocaine use, but the relation of CM treatment to criminal activities has rarely been studied. METHODS: This study evaluated whether baseline legal problems are related to subsequent substance use and illegal activities for cocaine using methadone maintained patients and whether CM differentially improves outcomes depending on baseline legal problems...
September 8, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28917206/maternal-and-infant-outcomes-following-third-trimester-exposure-to-marijuana-in-opioid-dependent-pregnant-women-maintained-on-buprenorphine
#2
Alane B O'Connor, Brandon K Kelly, Liam M O'Brien
BACKGROUND: To determine whether maternal and infant outcomes are associated with exposure to marijuana during the third trimester in a population of opioid dependent pregnant women maintained on buprenorphine. METHODS: This retrospective cohort study of 191 maternal-infant dyads exposed to buprenorphine during pregnancy examines a variety of variables including gestational age, birthweight, method of delivery, Apgar scores at one and five minutes, duration of infant hospital stay, peak neonatal abstinence syndrome (NAS) score, duration of NAS and incidence of pharmacologic treatment of NAS in infants exposed to marijuana during the third trimester as compared to infants not exposed to marijuana during the third trimester...
September 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28903079/escalating-patterns-of-emergency-health-care-prior-to-first-admission-with-amphetamine-psychosis-a-window-of-opportunity
#3
Grant Sara, Julia Lappin, Timothy Dobbins, Adrian J Dunlop, Louisa Degenhardt
AIM: To describe health service contact in the two years prior to a first hospital admission with amphetamine-related psychosis, and to identify possible opportunities for early intervention. METHOD: Routine health data collections were used to identify 6130 persons aged 16-65 who had a first hospital admission with amphetamine-related psychosis in New South Wales (NSW), Australia, between 2005 and 2016. Health service contacts in the two years prior to first admission were identified, using public hospital, emergency department and community mental health data...
September 6, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28892720/physicians-in-training-are-not-prepared-to-prescribe-medical-marijuana
#4
Anastasia B Evanoff, Tiffany Quan, Carolyn Dufault, Michael Awad, Laura Jean Bierut
BACKGROUND: While medical marijuana use is legal in more than half of U.S. states, evidence is limited about the preparation of physicians-in-training to prescribe medical marijuana. We asked whether current medical school and graduate medical educational training prepare physicians to prescribe medical marijuana. METHODS: We conducted a national survey of U.S. medical school curriculum deans, a similar survey of residents and fellows at Washington University in St...
September 4, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28888150/gender-differences-in-trajectories-of-alcohol-use-from-ages-13-to-33-across-latina-o-ethnic-groups
#5
Michael D Niño, Tianji Cai, Xóchitl Mota-Back, Joseph Comeau
BACKGROUND: Research examining alcohol use trajectories among Latina/os is scarce. Further, prior findings on alcohol use by ethnic group and gender is mixed. The purpose of this study was twofold: (a.) to examine developmental trajectories for two types of alcohol (drunkenness and heavy drinking) use across four Latina/o ethnic groups (Cubans, Puerto Ricans, Central/South American, and Mexican Americans) and, (b.) to examine the role of gender and ethnicity in developmental trajectories of drunkenness and heavy drinking among Latina/os...
September 4, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28888149/the-impact-of-alcohol-policies-on-alcohol-attributable-diseases-in-taiwan-a-population-based-study
#6
Yung-Hsiang Ying, Yung-Ching Weng, Koyin Chang
BACKGROUND: Taiwan has some of the strictest alcohol-related driving laws in the world. However, its laws continue to be toughened to reduce the ever-increasing social cost of alcohol-related harm. AIM: This study assumes that alcohol-related driving laws show a spillover effect such that behavioral changes originally meant to apply behind the wheel come to affect drinking behavior in other contexts. The effects of alcohol driving laws and taxes on alcohol-related morbidity are assessed; incidence rates of alcohol-attributable diseases (AAD) serve as our measure of morbidity...
September 4, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28888154/factors-associated-with-an-evidence-based-measure-of-implementation-for-the-adolescent-community-reinforcement-approach
#7
Bryan R Garner, Sarah B Hunter, Mary E Slaughter, Bing Han, Susan H Godley
BACKGROUND: An evidence-based measure of implementation (EBMI) is an implementation outcome measure shown to have predictive validity with one or more future-measured constructs of importance. The current study sought to identify correlates and predictors of an EBMI called procedure exposure. Garner et al. (2016) found procedure exposure to be an EBMI for the Adolescent Community Reinforcement Approach (A-CRA). METHODS: The dataset included 76 community-based substance use treatment organizations located across the United States...
September 2, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28910690/smoking-cessation-for-substance-misusers-a-systematic-review-of-qualitative-studies-on-participant-and-provider-beliefs-and-perceptions
#8
REVIEW
Sarah Gentry, Jean Craig, Richard Holland, Caitlin Notley
INTRODUCTION: Smoking prevalence among those in substance misuse treatment remains much higher than the general population, despite evidence for effective cessation interventions that do not negatively impact substance misuse outcomes. This systematic review summarises qualitative data on barriers and facilitators to smoking cessation for people in substance misuse treatment, participants' and providers' perceptions about effects of smoking cessation on substance misuse treatment, timing of intervention delivery and aspects of interventions perceived to be effective...
September 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28886396/alcohol-and-depression-evidence-from-the-2014-health-survey-for-england
#9
S Awaworyi Churchill, L Farrell
BACKGROUND: A relatively large body of literature examines the association between depression and alcohol consumption, with evidence suggesting a bidirectional causal relationship. However, the endogeneity arising from this reverse causation has not been addressed in the literature. METHODS: Using data on 5828 respondents from the Health Survey for England (HSE), this study revisits the relationship between alcohol and depression and addresses the endogenous nature of this relationship...
September 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28915478/studying-the-interactive-effects-of-menthol-and-nicotine-among-youth-an-examination-using-e-cigarettes
#10
Suchitra Krishnan-Sarin, Barry G Green, Grace Kong, Dana A Cavallo, Peter Jatlow, Ralitza Gueorguieva, Eugenia Buta, Stephanie S O'Malley
BACKGROUND: Tobacco products containing menthol are widely used by youth. We used e-cigarettes to conduct an experimental evaluation of the independent and interactive effects of menthol and nicotine among youth. PROCEDURES: Pilot chemosensory experiments with fourteen e-cigarette users identified low (barely perceptible, 0.5%) and high (similar to commercial e-liquid, 3.5%) menthol concentrations. Sixty e-cigarette users were randomized to a nicotine concentration (0mg/ml, 6mg/ml, 12mg/ml) and participated in 3 laboratory sessions...
August 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28892721/glial-and-neuroinflammatory-targets-for-treating-substance-use-disorders
#11
REVIEW
Ryan K Bachtell, Jermaine D Jones, Keith G Heinzerling, Patrick M Beardsley, Sandra D Comer
BACKGROUND: The plenary session at the 2016 Behavior, Biology and Chemistry: Translational Research in Addiction Conference focused on glia as potential players in the development, persistence and treatment of substance use disorders. Glia partake in various functions that are important for healthy brain activity. Drugs of abuse alter glial cell activity producing several perturbations in brain function that are thought to contribute to behavioral changes associated with substance use disorders...
August 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28888153/life-events-and-alcohol-use-disorder-clinical-course-modeling-the-dynamic-association
#12
Marketa Krenek, Mark A Prince, Stephen A Maisto
BACKGROUND: Despite over 35 years of study, the relationship between life events (LEs) and alcohol use disorder (AUD) treatment outcome lacks consistent empirical support, which may be due to a lack of theoretically driven designs and corresponding statistical analyses. The purpose of this study was to elucidate the LEs-AUD treatment outcome relationship by statistically modeling the dynamic relationship between negative LEs and alcohol use post-treatment, as it is conceptualized within the dynamic model of relapse...
August 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28881319/acute-effects-of-intravenous-cocaine-administration-on-serum-concentrations-of-ghrelin-amylin-glucagon-like-peptide-1-insulin-leptin-and-peptide-yy-and-relationships-with-cardiorespiratory-and-subjective-responses
#13
Sofia Bouhlal, Kayla N Ellefsen, Mikela B Sheskier, Erick Singley, Sandrine Pirard, David A Gorelick, Marilyn A Huestis, Lorenzo Leggio
BACKGROUND: Food intake and use of drugs of abuse like cocaine share common central and peripheral physiological pathways. Appetitive hormones play a major role in regulating food intake; however, little is known about the effects of acute cocaine administration on the blood concentrations of these hormones in cocaine users. METHODS: We evaluated serum concentrations of six appetitive hormones: ghrelin (total and acyl-ghrelin), amylin, glucagon-like peptide-1 (GLP-1), insulin, leptin and peptide YY (PYY), as well as acute cardiorespiratory and subjective responses of 8 experienced cocaine users who received 25mg intravenous (IV) cocaine...
August 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28869859/maternal-buprenorphine-treatment-and-infant-outcome
#14
Lauren M Jansson, Martha L Velez, Krystle McConnell, Nancy Spencer, Michelle Tuten, Hendree Jones, Rebeca Rios, Van L King, Neeraj Gandotra, Lorraine Millio, Janet A DiPietro
BACKGROUND AND OBJECTIVES: Maternal buprenorphine maintenance predisposes the infant to exhibit neonatal abstinence syndrome (NAS), but there is insufficient published information regarding the nature of NAS and factors that contribute to its severity in buprenorphine-exposed infants. METHODS: The present study evaluated forty-one infants of buprenorphine-maintained women in comprehensive substance use disorder treatment who participated in an open-label study examining the effects of maternal buprenorphine maintenance on infant outcomes...
August 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28869858/internalized-stigma-as-an-independent-risk-factor-for-substance-use-problems-among-primary-care-patients-rationale-and-preliminary-support
#15
Magdalena Kulesza, Katherine E Watkins, Allison J Ober, Karen C Osilla, Brett Ewing
BACKGROUND: Little is known about internalized stigma among primary care patients, and whether the presence of internalized stigma is related to the severity of substance use problems independent of substance use-related variables. We sought to examine the relationship between internalized stigma and substance use problems among primary care patients with opioid or alcohol use disorders (OAUDs). METHODS: We present baseline data from 393 primary care patients who were enrolled in a study of collaborative care for OAUDs...
August 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28858670/generalised-inhibitory-impairment-to-appetitive-cues-from-alcoholic-to-non-alcoholic-visual-stimuli
#16
Rebecca L Monk, Adam Qureshi, Charlotte R Pennington, Iain Hamlin
BACKGROUND: Prior research demonstrates that individuals who consume alcohol show diminished inhibitory control towards alcohol-related cues. However, such research contrasts predominantly alcoholic appetitive cues with non-alcoholic, non-appetitive cues (e.g., stationary items). As such, it is not clear whether it is specifically the alcoholic nature of the cues that influences impairments in inhibitory control or whether more general appetitive processes are at play. AIMS: The current study examined the hitherto untested assertion that the disinhibiting effects of alcohol-related stimuli might generalise to other appetitive liquid stimuli, but not to non-appetitive liquid stimuli...
August 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28888151/evaluation-of-the-ac-ok-mental-health-and-substance-abuse-screening-measure-in-an-international-sample-of-latino-immigrants
#17
Ligia M Chavez, Patrick E Shrout, Ye Wang, Francisco Collazos, Rodrigo Carmona, Margarita Alegría
BACKGROUND: Early detection and intervention in primary care is integral to behavioral health. Valid, practical screening assessments are scarce, particularly for non-English speaking populations. We address this need by evaluating the psychometric properties of the Spanish version of the AC-OK Screen for Co-occurring Disorders for first and second generation immigrant Latinos in Massachusetts, USA, and Madrid and Barcelona, Spain. METHODS: 567 Latino participants were recruited in waiting areas of clinics or by referral from Primary Care, Mental Health, Substance Use, and HIV Treatment Clinics, as well as Community Agencies...
August 24, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28881318/alcohol-and-substance-use-diagnoses-among-hiv-positive-patients-receiving-care-in-nyc-clinic-settings
#18
Sitaji Gurung, Ana Ventuneac, Demetria Cain, Chloe Mirzayi, Christopher Ferraris, H Jonathon Rendina, Martha A Sparks, Jeffrey T Parsons
BACKGROUND: Substance use among HIV-positive persons exacerbates health problems. This study sought to estimate the prevalence of alcohol and drug-use diagnoses and examined hypothesized predictors associated with alcohol and drug-use diagnoses among HIV-positive patients in New York City (NYC). METHODS: This cohort study reviewed electronic medical records (EMRs) of 4965 HIV-positive patients based on diagnostic codes. These patients attended a comprehensive care clinic in NYC in 2012...
August 24, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28866369/interpreting-quantitative-urine-buprenorphine-and-norbuprenorphine-levels-in-office-based-clinical-practice
#19
Joseph H Donroe, Stephen R Holt, Patrick G O'Connor, Nitin Sukumar, Jeanette M Tetrault
BACKGROUND: Quantitative urine buprenorphine testing is used to monitor patients receiving buprenorphine for the treatment of opioid use disorder (OUD), however the interpretation of urine buprenorphine testing is complex. Currently, interpretation of quantitative buprenorphine testing is guided by data from drug assay development studies and forensic labs rather than clinical treatment cohorts. METHODS: In this retrospective study, we describe the patterns of urine buprenorphine and norbuprenorphine levels in patients prescribed sublingual buprenorphine for OUD in an office-based addiction treatment clinic...
August 24, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28865391/discriminative-stimulus-and-locomotor-effects-of-para-substituted-and-benzofuran-analogs-of-amphetamine
#20
Sean B Dolan, Michael J Forster, Michael B Gatch
Novel psychoactive substances have maintained a prominent role in the global drug culture, despite increased regulation by governing bodies. Novel compounds continue to become available on the market, often in "Ecstasy" or "Molly" formulations in lieu of MDMA, at a much faster rate than they can be properly characterized. The current study aimed to investigate the discriminative stimulus and locomotor effects of three putatively entactogenic compounds that have become increasingly prevalent on the drug market: 5-(2-aminopropyl)-benzofuran (5-APB), 6-(2-aminopropryl)-2,3-dihydrobenzofuran (6-APDB), and 4-fluoroamphetamine (4-FA)...
August 24, 2017: Drug and Alcohol Dependence
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