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Neuropsychobiology

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https://www.readbyqxmd.com/read/29772573/chronobiology
#1
(no author information available yet)
No abstract text is available yet for this article.
May 17, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29739008/abstracts-of-award-winning-posters
#2
(no author information available yet)
No abstract text is available yet for this article.
May 8, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29694980/a-twelve-week-moderate-exercise-programme-improved-symptoms-of-depression-insomnia-and-verbal-learning-in-post-aneurysmal-subarachnoid-haemorrhage-patients-a-comparison-with-meningioma-patients-and-healthy-controls
#3
Flora Colledge, Serge Brand, Uwe Pühse, Edith Holsboer-Trachsler, Stefan Zimmerer, Ramona Schleith, Markus Gerber
OBJECTIVES: Deficits in psychological functioning, cognitive functioning, and sleep are frequently experienced by individuals who have survived aneurysmal subarachnoid haemorrhage (aSAH). Exercise has been shown to improve these domains; to date, it has never been explored in patients following aSAH. The aim of this exploratory study is to compare the effects of an exercise programme in this population with another patient group, and a group of healthy controls. METHODS: The present study explored the effects of 12 weeks of moderate aerobic exercise training on 15 aSAH patients, 16 meningioma patients, and 17 healthy controls...
April 25, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29694960/kynurenine-pathway-in-autism-spectrum-disorders-in-children
#4
Vesna Bryn, Robert Verkerk, Ola H Skjeldal, Ola Didrik Saugstad, Heidi Ormstad
BACKGROUND: There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory states, we aimed to determine whether this pathway is activated in ASD. METHODS: Sixty-five pediatric ASD patients (including 52 boys) were enrolled from an epidemiological survey covering 2 counties in Norway; 30 (46...
April 25, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29649810/female-gender-marital-and-family-problems-and-feelings-of-guilt-are-related-to-self-immolation-suicide-attempts
#5
Mohammad Ahmadpanah, Amir Hosein Rahighi, Mohammad Haghighi
BACKGROUND: Self-immolation (SI) is considered one of the most painful, dramatic, and at the same time most inexplicable methods of suicide, with a high social impact. Prevalence rates are particularly high in Iran, and in north-western Iran specifically. Here, we report sociodemographic, psychological, and psychiatric characteristics of patients attempting self-immolation (PSIs), compared to patients with accident burns (PABs). METHOD: Patients referred to the Burns Emergency Unit of the Besat Hospital (Hamadan, Iran) were enrolled in the present study between winter 2015 and summer 2016...
April 12, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29621775/association-of-polymorphisms-of-serotonin-transporter-5httlpr-and-5-ht2c-receptor-genes-with-criminal-behavior-in-russian-criminal-offenders
#6
Valentina A Toshchakova, Yalda Bakhtiari, Alexander V Kulikov, Sergey I Gusev, Marina V Trofimova, Olga Yu Fedorenko, Ekaterina V Mikhalitskaya, Nina K Popova, Nikolay A Bokhan, Johannes E Hovens, Anton J M Loonen, Bob Wilffert, Svetlana A Ivanova
BACKGROUND: Human aggression is a heterogeneous behavior with biological, psychological, and social backgrounds. As the biological mechanisms that regulate aggression are components of both reward-seeking and adversity-fleeing behavior, these phenomena are difficult to disentangle into separate neurochemical processes. Nevertheless, evidence exists linking some forms of aggression to aberrant serotonergic neurotransmission. We determined possible associations between 6 serotonergic neurotransmission-related gene variants and severe criminal offenses...
April 5, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29346785/impulsivity-and-saliva-cortisol-in-patients-with-suicide-attempt-and-controls
#7
Ute Lewitzka, Michael Bauer, Bettina Ripke, Thomas Bronisch, Lydia Günther
OBJECTIVES: The objective of this study was to prove concepts in the characterization of suicidal patients and the possible usefulness of those markers to potentially identify patients with a higher risk for suicidality. METHODS: Patients with a recent suicide attempt were compared with patients suffering from depression, adjustment disorder, anxiety, or eating disorders without suicidality, healthy controls and remitted patients with a history of at least 1 suicide attempt (≥1 year)...
January 18, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29339668/proinflammatory-cytokines-and-oxidative-stress-decrease-the-transport-of-dopamine-precursor-tyrosine-in-human-fibroblasts
#8
Ravi Vumma, Jessica Johansson, Nikolaos Venizelos
BACKGROUND: Proinflammatory cytokines and oxidative stress responses have been extensively implicated in the pathophysiology of neuropsychiatric disorders over the past 2 decades. Moreover, disturbed transport of the dopamine precursor (i.e., the amino acid tyrosine) has been demonstrated, in different studies, across fibroblast cell membranes obtained from neuropsychiatric patients. However, the role and influences of proinflammatory cytokines and oxidative stress, and the reasons for disturbed tyrosine transport in neuropsychiatric disorders, are still not evaluated...
January 16, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29035887/valeriana-officinalis-root-extract-modulates-cortical-excitatory-circuits-in-humans
#9
Ludovico Mineo, Carmen Concerto, Dhaval Patel, Tyrone Mayorga, Michael Paula, Eileen Chusid, Eugenio Aguglia, Fortunato Battaglia
BACKGROUND: Valeriana officinalis extract (VE) is a popular herbal medicine used for the treatment of anxiety and sleep disorders. Although the anxiolytic and sedative effects are mainly attributed to the modulation of GABA-ergic transmission, the mechanism of action has not been fully investigated in humans. Noninvasive brain stimulation protocols can be used to elucidate the mechanisms of action of psychoactive substances at the cortical level in humans. In this study, we investigated the effects of a single dose of VE on cortical excitability as assessed with transcranial magnetic stimulation (TMS)...
October 17, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29032375/erratum
#10
(no author information available yet)
No abstract text is available yet for this article.
October 13, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28848102/plasma-bdnf-level-in-major-depression-biomarker-of-the-val66met-bdnf-polymorphism-and-of-the-clinical-course-in-met-carrier-patients
#11
Romain Colle, Séverine Trabado, Denis J David, Sylvie Brailly-Tabard, Patrick Hardy, Bruno Falissard, Bruno Fève, Laurent Becquemont, Céline Verstuyft, Emmanuelle Corruble
AIMS: Despite the involvement of the brain-derived neurotrophic factor (BDNF) in the physiopathology of major depressive disorder (MDD), the coherence between the components of the BDNF pathway and their link with the clinical features of MDD are insufficiently studied. We aimed to assess in Caucasian depressed patients the impact of the BDNF Val66Met polymorphism on plasma BDNF levels taking into account the clinical characteristics of MDD. METHODS: A total of 328 Caucasian adult MDD patients with a current major depressive episode (MDE) were assessed for the BDNF Val66Met polymorphism, plasma BDNF levels and clinical characteristics of the MDD...
August 23, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28803247/potential-gender-related-aging-processes-occur-earlier-and-faster-in-the-vermis-of-patients-with-bipolar-disorder-an-mri-study
#12
Marta Serati, Giuseppe Delvecchio, Giulia Orsenigo, Cinzia Perlini, Marco Barillari, Mirella Ruggeri, Alfredo Carlo Altamura, Marcella Bellani, Paolo Brambilla
BACKGROUND: In the last decades, there has been increasing interest in investigating the role of the vermis in bipolar disorder (BD), especially because of its involvement in cognitive processes. The main aims of this study were to explore the integrity of the vermis and elucidate the role of demographic and clinical variables on vermis volumes in BD patients, stratified according to gender. METHODS: T1-weighted images were obtained for 38 BD patients and 38 healthy controls using a 1...
August 12, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28793304/frontal-cortex-myo-inositol-is-associated-with-sleep-and-depression-in-adolescents-a-proton-magnetic-resonance-spectroscopy-study
#13
Anna S Urrila, Antti Hakkarainen, Anu Castaneda, Tiina Paunio, Mauri Marttunen, Nina Lundbom
AIM: This study used proton magnetic resonance spectroscopy (1H MRS) to evaluate the neurochemistry of the frontal cortex in adolescents with symptoms of sleep and depression. METHODS: Nineteen non-medicated adolescent boys (mean age 16.0 years; 9 clinical cases with depression/sleep symptoms and 10 healthy controls) underwent 1H MRS at 3 T. MR spectra were acquired from the anterior cingulate cortex (ACC), the dorsolateral prefrontal cortex, and frontal white matter...
August 10, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28750407/in-individuals-following-aneurysmal-subarachnoid-haemorrhage-hair-cortisol-concentrations-are-higher-and-more-strongly-associated-with-psychological-functioning-and-sleep-complaints-than-in-healthy-controls
#14
Flora Colledge, Serge Brand, Stefan Zimmerer, Uwe Pühse, Edith Holsboer-Trachsler, Markus Gerber
BACKGROUND: Following an aneurysmal subarachnoid haemorrhage (aSAH), many patients report persistent deficits in psychological functioning, characterised by high levels of stress and symptoms of depression, low life satisfaction, along with poor sleep. Such deficits have been associated with altered saliva and serum cortisol levels due to a dysregulation of hypothalamic-pituitary-adrenal axis activity (HPA-AA). However, hair cortisol concentrations (HCCs) have not been assessed in this population, although this method allows a long-term insight into cortisol values...
July 28, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28700991/strain-differences-and-effects-of-environmental-manipulation-on-astrocytes-glial-fibrillary-acidic-protein-glucocorticoid-receptor-and-microglia-iba1-immunoreactivity-between-wistar-kyoto-and-wistar-females
#15
Guergana R Mileva, Carinna Moyes, Shaezeen Syed, Catherine Bielajew
BACKGROUND: Depression is often associated with an increase in hypothalamic-pituitary-adrenal (HPA) axis reactivity and immune response. To investigate this relationship, we examined the consequences of environmental manipulation on the neural correlates of the HPA axis and immune response in an animal model of depression, the Wistar-Kyoto (WKY) rat. Additionally, female animals are often overlooked in preclinical research because of the hormone fluctuations inherent in the estrous cycle...
July 13, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28178693/abstracts-of-award-winning-posters-16th-international-forum-on-mood-and-anxiety-disorders-rome-december-8-10-2016
#16
(no author information available yet)
No abstract text is available yet for this article.
February 9, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29510398/epigenetic-effects-of-intravenous-diacetylmorphine-on-the-methylation-of-pomc-and-nr3c1
#17
Adrian Groh, Mathias Rhein, Vanessa Buchholz, Alexandra Burkert, Christian G Huber, Undine E Lang, Stefan J Borgwardt, Annemarie Heberlein, Marc A N Muschler, Thomas Hillemacher, Stefan Bleich, Helge Frieling, Marc Walter
The administration of diacetylmorphine (DAM) reduces the activation of the hypothalamic-pituitary-adrenal (HPA) axis in opioid-maintained patients. However, the epigenetic effects of DAM on addiction-related genes have not been investigated yet. In a randomized controlled study, we examined the immediate effects of intravenous DAM versus placebo on the promoter methylation of the POMC (pro- opiomelanocortin) and NR3C1 (glucocorticoid receptor 1) genes. Twenty-eight heroin-dependent patients on DAM-assisted treatment received either DAM or saline in a randomized crossover design and 17 healthy participants received saline only...
2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29466802/healthy-and-pathological-brain-aging-from-the-perspective-of-oscillations-functional-connectivity-and-signal-complexity
#18
Ryouhei Ishii, Leonides Canuet, Yasunori Aoki, Masahiro Hata, Masao Iwase, Shunichiro Ikeda, Keiichiro Nishida, Manabu Ikeda
Healthy aging is associated with impairment in cognitive information processing. Several neuroimaging methods such as functional magnetic resonance imaging, positron emission tomography and near-infrared spectroscopy have been used to explore healthy and pathological aging by relying on hemodynamic or metabolic changes that occur in response to brain activity. Since electroencephalography (EEG) and magnetoencephalography (MEG) are able to measure neural activity directly with a high temporal resolution of milliseconds, these neurophysiological techniques are particularly important to investigate the dynamics of brain activity underlying neurocognitive aging...
2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29402816/further-evidence-of-the-positive-influence-of-repetitive-transcranial-magnetic-stimulation-on-speech-and-language-in-patients-with-aphasia-after-stroke-results-from-a-double-blind-intervention-with-sham-condition
#19
Mohammad Haghighi, Mehrdokht Mazdeh, Nazila Ranjbar, Mohammad Ali Seifrabie
BACKGROUND: After a stroke, up to 20% of patients suffer from aphasia. The preferred treatment for stroke-related aphasia (SRA) is regular speech and language training (SLT). In the present study, we investigated to what extent adjuvant repetitive transcranial magnetic stimulation (rTMS) might enhance recovery. While there is growing evidence of the positive effect of adjuvant rTMS on aphasia, no study has yet been based on an Iranian sample. METHOD: A total of 12 patients (mean age: 55 years; right-handed; 7 women) underwent treatment for SRA 1 month after stroke...
2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29402784/parallel-effects-of-methamphetamine-on-anxiety-and-ccl3-in-humans-and-a-genetic-mouse-model-of-high-methamphetamine-intake
#20
Marilyn Huckans, Clare J Wilhelm, Tamara J Phillips, Elaine T Huang, Rebekah Hudson, Jennifer M Loftis
BACKGROUND: Methamphetamine (MA) abuse causes immune dysfunction and neuropsychiatric impairment. The mechanisms underlying these deficits remain unidentified. METHODS: The effects of MA on anxiety-like behavior and immune function were investigated in mice selectively bred to voluntarily consume high amounts of MA [i.e., MA high drinking (MAHDR) mice]. MA (or saline) was administered to mice using a chronic (14-day), binge-like model. Performance in the elevated zero maze (EZM) was determined 5 days after the last MA dose to examine anxiety-like behavior...
2017: Neuropsychobiology
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