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Zhonghua Yi Xue za Zhi [Chinese medical journal]

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https://www.readbyqxmd.com/read/30220175/-a-retrospective-study-of-the-mortality-and-death-related-risk-factors-of-patients-hospitalized-for-asthma-exacerbation-in-chinese-urban-areas
#1
J T Lin, B Xing, H P Tang, L Yang, Y D Yuan, Y H Gu, P Chen, X J Liu, J Zhang, H G Liu, C Z Wang, W Zhou, D J Sun, Y Q Chen, Z C Chen, M Huang, Q C Lin, C P Hu, X H Yang, J M Huo, X W Ye, X Zhou, P Jiang, W Zhang, Y J Huang, L M Dai, R Y Liu, S X Cai, J Y Xu, J Y Zhou
Objective: To study the mortality and death-related risk factors of patients hospitalized for asthma exacerbation in Chinese urban areas. Methods: A retrospective study was carried out in 29 hospitals of 29 provinces throughout mainland China. Patients hospitalized for asthma exacerbation during 2013-2014 in each hospital were included. For each patient, information about demography, admission time, comorbidities, severity of diseases, intense care unit (ICU) admission, use of mechanical ventilation and the outcome was obtained...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220174/-effect-of-different-genotypes-of-pnpla3-i148m-on-hepatocyte-proliferation
#2
X M Yan, S H Yuan, X Xu, H Y Ai, H Liang
Objective: To explore the influence of patatin-like phospholipase domain containing-3 (PNPLA3) wild type 148I/I and mutant type 148M/M on HepG2 cell proliferation and the relative mechanisms. Methods: HepG2 cell line stably overexpressing PNPLA3 148I/I, 148M/M and negative control (NC) were set up. Cell counting kit-8 (CCK8) assay was used to measure cell viability. Edu assay was used to determine the ability of cell proliferation. Western blot was used to detect the protein levels in the phosphatidylinositol 3-kinases (PI3K) pathway...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220173/-effect-and-mechanism-of-microrna-146a-on-tlr4-inflammatory-signal-pathway-in-the-lung-tissues-of-rats-with-mechanical-ventilator-induced-lung-injury
#3
X Lin, L Y Xu, X H Li, T X Yu, Q Lin, L Chen, Y W Bao
Objective: To investigate the effect and mechanism of microRNA-146a (miR-146a) on Toll-Like Receptor 4 (TLR4) inflammatory signal pathway in the lung tissues of rats with mechanical ventilator-induced lung injury. Methods: Thirty-two healthy male Sprague-Dawley rats were randomly divided into 4 groups ( n =8 each): group A, normal control group, no mechanical ventilation, spontaneous breathing; group B, mechanical ventilation injury; group C, mechanical ventilation injury plus no-load virus transfection; group D, mechanical ventilation injury plus virus transfection; in group B, C, and D, mechanical ventilation were performed, respiratory rate was controlled at 80 beats/min, tidal volume was 40 ml/kg, inhaled oxygen concentration (FiO2 ) was 21%, inhalation/expiration ratio was 1∶2, positive end expiratory pressure ventilation (PEEP) was 0, each group were ventilated 4 hours daily, 7 days continuously to establish ventilator induced lung injury (VILI) rat model...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220172/-effects-of-tlr4-pi3k-rac1-pathway-on-cytoskeleton-rearrangement-and-phagocytosis-of-macrophage
#4
F Li, J L Chen, X L Zeng, H R Bao, X J Liu
Objective: To investigate the effects of Toll-like receptor 4 (TLR4)-phosphatidylinositol 3-kinase (PI3K) -Ras-related C3 botulinum toxin 1 (Rac1) signaling pathway on macrophage cytoskeleton rearrangement and phagocytosis. Methods: Mouse macrophage cell line RAW264.7 was divided into blank group, negative control group and TLR4-RNA interference (RNAi) group. The lentivirus carrying TLR4 short hairpin RNA (shRNA) and nonsense control sequence were respectively transfected into TLR4-RNAi group and negative control group...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220171/-the-impact-of-genetic-variation-of-kdr-on-clinical-outcomes-of-advanced-colorectal-cancer-patients-treated-by-first-line-bevacizumab-based-regimens
#5
H X Wang, X Mei, T X Gong, N Han, P Liu, J Wang, Z M Zhang
Objective: To investigate the association between kinase insertion region receptor (KDR) gene genetic variation and the efficacy of bevacizumab in patients with advanced colorectal cancer(CRC) were investigated in this study. Methods: 118 patients with advanced colorectal cancer who were treated by bevacizumab based first line regimens were included in this study. Peripheral blood and the biopsy tissue specimens of the CRC patients were collected for the genotyping of genetic variation and KDR gene expression, respectively...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220170/-a-comparative-study-of-cold-snare-and-hot-snare-resection-of-small-colorectal-polyps
#6
Y Wang, X Li, L Zhang, P Bai, X S Yang, Y H Huang, X C Lin
Objective: To compare the effect of cold snare and hot snare on the resection of small colorectal polyps, and to explore the clinical value of cold snare technique in removing colorectal polyps. Methods: From September 1, 2017 to January 31, 2018, 206 cases of patients with colorectal polyp resection in the Department of Gastroenterology of Peking University International Hospital were studied. During this period, according to the standard, 103 cases of patients (158 polyps) were in the cold snare group, and 103 patients (180 polyps) were randomly selected as control group from patients of the hot snare group...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220169/-clinical-characteristics-of-silent-pheochromocytoma
#7
H Yang, H H Wu, N Bu, L Zhou, J Q Zhang, L Q Zhou, X H Guo
Objective: To summarize the clinical characteristics of silent paraganglioma. Methods: A total of 247 pheochromocytoma cases in Peking University First Hospital between January 1993 and December 2015 were analyzed retrospectively.The cases were divided into two groups according to whether they had hypertension: non-silent group (193 cases) and silent group (53 cases), then the clinical characteristics between the groups were compared, and the clinical features of silent pheochromocytoma were reviewed. Results: There were 53 silent pheochromocytoma cases in this study, which accounted for 21...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220168/-clinical-characteristics-and-prognosis-analysis-of-46-cases-of-newly-diagnosed-localized-head-and-neck-rhabdomyosarcoma
#8
C G Zhang, S Y Zhou, P Liu, Y Qin, J L Yang, X H He, Y K Shi
Objective: To analyze the clinical characteristics and prognosis of newly diagnosed localized head and neck rhabdomyosarcoma. Methods: Cases of newly diagnosed localized head and neck rhabdomyosarcoma between January 2006 and December 2016 were analyzed retrospectively. The clinical features of the patients were described. The Kaplan-Meier method was used to analyze the survival rate under different combined modality therapy and the survival rate with or without chemotherapy. The prognostic factors were analyzed by Cox model...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220167/-the-role-of-prophylactic-use-of-pegylated-recombinant-human-granulocyte-colony-stimulating-factor-peg-rhg-csf-in-breast-cancer-receiving-adjuvant-chemotherapy
#9
J Y Zhang, Y X Liu, H Wang, L Mi, G H Song, H F Jiang, Y Yan, B Shao, W Y Kong, R Y Zhang, R Ran, X R Liu, J Wang, Y T Lin, H P Li
Objectives: To investigate the efficacy and safety of prophylactic use of pegylated recombinant human granulocyte colony-stimulating factor(PEG-rhG-CSF) in breast cancer receiving docetaxel as adjuvant chemotherapy. Methods: A total of 58 patients with breast cancer receiving adjuvant chemotherapy with docetaxel were included between January 2014 to October 2017. Prophylactic use of PEG-rhG-CSF was administered.Patients were further divided into two groups according to the frequency of PEG-rhG-CSF use: frequent use group (≥3 cycles) and non-frequent use group (<3 cycles)...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220166/-clinical-analysis-of-hepatic-perivascular-epithelioid-cell-neoplasm-a-report-of-eleven-cases
#10
G Y Wang, C Zhao, D F Hou, M W Yang, X R Hu, Z H Liu, X M Bu
Objective: To investigate the clinical features, diagnosis and therapy of hepatic perivascular epithelioid neoplasms (PEComa). Methods: The clinical data of eleven patients with hepatic PEComa who received surgical treatment at Shengjing Hospital Affiliated to China Medical University from April 2012 to October 2017 were collected. The clinical manifestations, imaging features, diagnostic and therapeutic strategies, pathologic features, prognosis were analyzed. Results: The patients aged from 35 to 55 years (mean: 47 years , 3 males and 8 females)...
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220165/-medication-and-biologic-treatment-of-acute-respiratory-distress-syndrome
#11
H Luo, S Z Ding, X R Zhang
No abstract text is available yet for this article.
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220164/-heterogeneity-of-pathophysiological-characteristics-of-acute-respiratory-distress-syndrome
#12
P H Pan, C Song, M H Dai
No abstract text is available yet for this article.
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220163/-extracorporeal-membrane-oxygenation-hope-of-severe-acute-respiratory-distress-syndrome
#13
B Sun, X Tang
No abstract text is available yet for this article.
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220162/-personalized-mechanical-ventilation-guided-by-pulmonary-mechanics-in-acute-respiratory-distress-syndrome-patients
#14
L X Xie, Y Wang
No abstract text is available yet for this article.
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220161/-definition-changes-of-acute-respiratory-distress-syndrome-over-the-past-50-years
#15
Q Y Zhan, X Yu
No abstract text is available yet for this article.
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220160/-the-concept-and-application-of-intelligence-medicine
#16
R Liu
No abstract text is available yet for this article.
September 11, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220159/-targeting-diagnosis-and-treatment-value-of-chelating-anti-il-1%C3%AE-mab-spions-in-temporal-lobe-epilepsy-model
#17
Y L Wang, X B Hu, L Y Gao, X R Wu, X Chu, S H Zhou, Q X Kong
Objective: In order to study the diagnosis and treatment value of chelating anti-IL-1β mAb-SPIONs in temporal lobe epilepsy model induced by lithium chlorid and pilocarpine. Methods: Forty-five temporal lobe epilepsy model rats were randomly and equally divided into saline group, plain-SPIONs group, anti-IL-1β mAb-SPIONs group. Each group was injected with equal particles at day 3 and day 14 after the onset of seizures. MRI were conducteds before and 4 hours after particles injection and T2 values were measured...
September 4, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220158/-application-of-transperineal-pelvic-floor-ultrasonography-in-the-diagnosis-of-female-stress-urinary-incontinence
#18
R Lu, Y Zhang, F R Dai, Y P Yu
Objective: To explore the application of transperineal pelvic floor ultrasonography in the diagnosis of female stress urinary incontinence(SUI). Methods: From March 2017 to December 2017, 60 patients diagnosed with SUI by department of gynecology, Xiangya Hospital of Central South University were selected as the case group, and 30 cases of normal women in the same period were selected as the control group. All subjects in both groups were examined by transperineal pelvic floor ultrasonography, that is, to be measured the bladder neck descent(BND), the urethral inclination angle(UIA), the posterior urethrovesical angle(PUVA) and the levator hiatus area(LHA) in resting state and during Valsalva maneuver...
September 4, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220157/-clinical-evaluation-of-dry-chemical-enzyme-method-for-detecting-neisseria-gonorrhoeae-and-analysis-of-external-quality-assessment-results
#19
Y F Wang, S S Tai, H Y Yang
Objective: Neisseria gonorrhoeae in female cervix sample was detected by dry chemical enzymatic method and culture method. The detection effects of two detection methods were analyzed to provide reference for clinical detection. At the same time, strains were separated and identified to evaluate reliability of different methods. Methods: During October 2015 to December 2017, 8 860 samples of female cervix from the Third Affiliated Hospital of Zhengzhou University and Henan Provincial Peoples Hospital were detected by dry chemical enzymatic method and culture method...
September 4, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30220156/-virtual-planning-and-3d-printing-modeling-for-mandibular-reconstruction-with-fibula-free-flap
#20
W H Ren, L Gao, S M Li, F Li, Y Zhi, J Z Song, Q B Wang, L F Xue, Z G Qu, K Q Zhi
Objective: To evaluate the use of virtual planning and 3D printing modeling in mandibular reconstruction and compare the operation time and surgical outcome of this technique with conventional method. Methods: Between June 2013 and June 2017, A total of 18 patients underwent the mandibular reconstruction with fibula free flap in the Affiliated Hospital of Qingdao University.Among 18 patients, there were 11 males and 7 females with an average age of 36.5 years (21-73 years). Nine patients underwent vascularized fibula flap mandibular reconstruction using virtual planning and 3D printing modeling...
September 4, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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