journal
MENU ▼
Read by QxMD icon Read
search

Zhonghua Yi Xue za Zhi [Chinese medical journal]

journal
https://www.readbyqxmd.com/read/30440142/-mechanism-of-mir-221-contributes-to-gefitinib-resistance-in-pc-9-cells
#1
Y Y Gao, X H Kang, Y Wang, K L Zhao, Y N Wang, W Z Kou, Z H Miao, P Lu
Objective: To investigate the effect of microRNA-221 (miR-221) overexpression on gefitinib resistance in PC-9 cells and study its underlying mechanisms. Methods: PC-9 cells were transfected with LV-NC and LV-miR-221 to establish cell stabilizing strains (PC-9/NC and PC-9/miR-221), then they were used to detect the relative expression of miR-221 and apoptotic protease activating factor-1 (APAF-1) mRNA by real-time fluorescence quantitative PCR (qRT-PCR). The effects of gefitinib (0-4 μmol/L) on the growth and proliferation of cell stabilizing strains were detected by CCK-8 Assay...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440141/-clinical-analysis-of-igg4-related-lung-disease
#2
M Wu, L Wang, Y Ji, G G Shang, Q Y Hong
Objective: To improve the understanding and treatment of IgG4-related lung disease (IgG4-RLD) by analyzing the clinical characteristics of patients. Methods: A total of 13 patients with IgG4-related lung disease (IgG4-RLD) diagnosed by pathology at Zhongshan Hospital affiliated to Fudan University during December 2007 to December 2017 were included. The clinical characteristics, chest CT, pathological features, serum IgG4 levels, therapy and prognosis of these 13 patients were analyzed. Results: The 13 patients with IgG4-RLD included 8 men and 5 women, with an average age of (51...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440140/-correlation-between-serum-cd147-and-carotid-intraplaque-hemorrhage
#3
W C Guo, M Cui, X Wang, H Y Tao, B Yu
Objective: Intraplaque hemorrhage (IPH) is one of the most important causes of ischemic stroke. The purpose of this study was to explore the association between carotid IPH and CD147, which may be the serum marker related to IPH. Methods: Serum samples were collected from 68 patients with carotid artery stenosis from April to September 2004. 3.0T MRI with the 8 channel surface coil was used to scan carotid artery. Images was processed by MRI-PlaqueView. The integrity of lipid, IPH, calcified components and fibrous cap in the plaque was analysed qualitatively and quantitatively...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440139/-the-technique-and-efficacy-of-complete-resection-of-mesogastrium-above-the-pancreas-by-the-right-approach-in-laparoscopic-assisted-distal-gastrectomy-for-radical-gastrectomy
#4
J Min, K Qian, X X Wu, Z W Wang, W Zhang
Objective: To explore the safety and efficacy of mesogastrium excision above the pancreas by the right approach in radical distal gastrectomy for cancer. Methods: A total of 154 distal gastric cancer patients in the Department of Gastrointestinal Surgery of the first affiliated Hospital of Chongqing Medical University, from October 2013 to October 2014, were included in this random controlled study. These patients were divided into the study group ( n =78), who received mesogastrium excision above the pancreas by the right approach, and the control group ( n =76), who received mesogastrium excision above the pancreas when by the left approach...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440138/-study-of-de-novo-point-mutations-in-known-genes-among-patients-with-unexplained-intellectual-disability-or-developmental-delay
#5
Z J Gao, Q Jiang, X L Chen, Q Chen, X N Ji, Y Y Mao, S Feng, J J Dong, K M Xu
Objective: To analyze the de novo point mutations in known genes among patients with unexplained intellectual disability (ID) or developmental retardation (DD). Methods: A total of 120 outpatients with ID or DD were recruited in the Department of Neurology, Affiliated Children's Hospital of Capital Institute of Pediatrics between September 2015 and April 2017. Target gene sequencing was used to screen the candidate gene. The sequencing data were analyzed by a variety of bioinformatics software. Combining with the phenotypes of the patients, the candidate genetic/genomic variants were identified from next-generation sequencing data...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440137/-clinical-outcomes-of-gastric-cancer-patients-received-capecitabine-based-adjuvant-chemotherapy-and-the-corresponding-pharmacogenomics-analysis
#6
W C Chen, G Wu, W Zhang, Y Z Zhu, Y Zhou, H Zhang, X B Xia, P C Sun
Objective: To investigate the association between Thymidine phosphorylase(TYMP)genetic variation and clinical outcomes of postoperative gastric cancer (GC) patients received capecitabine based regimens. Methods: A total of 198 GC patients underwent surgical treatment and received capecitabine based adjuvant chemotherapy were included in this retrospective study. Peripheral blood and the postoperative tissue specimen of the GC patients were collected for the genotyping of polymorphism and TYMP mRNA expression, respectively...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440136/-value-of-rna-oxidation-product-8-oxo-gsn-in-evaluating-renal-function-in-patients-with-chronic-kidney-disease
#7
L N Xu, B Zhao, H T Wang, J P Cai, Y H Mao
Objective: To investigate the relationship of DNA oxidative product 8-oxo-dGsn and RNA oxidative product 8-oxo-Gsn with chronic kidney disease (CKD). Methods: Between January 2015 and December 2016, 146 cases of CKD (30, 30, 31, 30 and 25 cases of CKD stage 1-5, respectively) were collected in the Department of Nephrology in Beijing Hospital. Among them, 70 cases were male, accounting for 47.95%. The age distribution ranged from 21 to 88 years, with an average age of (56.43±16.79) years. Their fasting blood and morning urine were collected...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440135/-relationship-between-visceral-obesity-and-atherosclerosis-in-hemodialysis-patients
#8
P H He, Y L Min, C M Zhou, X Y Tong, X Lin, Q Li, Y Zha
Objective: To evaluate the relationship between surrogate markers of visceral obesity[hypertriglyceridemic waist (HW) phenotype, visceral adiposity index (VAL), lipid accumulation product (LAP)]and atherosclerosis in hemodialysis patients. Methods: A multi-center cross-sectional study was carried out. A total of 961 maintenance hemodialysis (MHD) patients from 11 hemodialysis centers of Guizhou province between July 2016 and September 2017 were enrolled in the study. Anthropometric measures were performed in all subjects...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440134/-effect-of-hyperphosphatemia-on-patency-rate-of-arteriovenous-fistula-of-patients-with-late-fistula-dysfunction-failure-after-reoperation
#9
M Zhou, F P Lu
Objective: To investigate the effect of hyperphosphatemia on long-term patency of arteriovenous fistula (AVF) of patients with late fistula dysfunction/failure after reoperation. Methods: The study was carried out in the Department of Nephrology of the First Affiliated Hospital of Tsinghua University between March 2012 and March 2013. A total of 136 maintenance hemodialysis patients[73 males, 63 females, with an average age of (57.7±16.1) years]with late AVF dysfunction/faliure who received AVF reoperation were enrolled in the study...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440133/-association-of-low-serum-parathyroid-hormone-with-protein-energy-wasting-in-maintenance-hemodialysis-patients
#10
F X Su, J Wu, C M Zhou, Q Li, S S Hu, X Lin, J J Da, Y Zha
Objective: To examine the relationship between low serum parathyroid hormone (PTH) and protein-energy wasting (PEW) in patients who underwent maintenance hemodialysis (MHD) treatment. Methods: A cross-sectional study was conducted in MHD patients between June 2015 and August 2017 in 11 MHD centers from Guizhou province. Body composition and physical parameters were measured, clinical data and other related laboratory values were collected according to the medical record system. Participants were assigned to low serum PTH group (PTH<150 ng/L), target PTH group (150 ng/L≤ PTH ≤300 ng/L) and high serum PTH group (PTH>300 ng/L)...
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440132/-evaluation-of-protein-energy-wasting-in-maintenance-hemodialysis-patients
#11
Y Zha, F Sun
No abstract text is available yet for this article.
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440131/-effects-of-interaction-between-fructose-and-intestinal-microflora-on-chronic-kidney-disease-progression
#12
Y Du, J S Jia, W J Yuan
No abstract text is available yet for this article.
November 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440130/-relationship-between-ugt1a4-142t-g-polymorphism-and-serum-concentration-of-lamotrigine-in-chinese-epileptic-patients-a-meta-analysis
#13
Z Li, Y Wang
Objective: To investigate the relationship between the polymorphism of Uridine diphosphate glucuronosyltransferases (UGT)1A4 142T>G (*3, L48V, rs 2011425)and serum concentration of lamotrigine(LTG) in Chinese epileptic patients. Methods: Databases including Cochrane Library, PubMed, Embase, CNKI, VIP and Wanfang were searched for the studies on the relationship of the polymorphisms of UGT1A4 142T>G with concentration of LTG (from the establishment a database to December 1, 2017). Meta-analysis was performed by RevMan 5...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440129/-hiv-epidemic-among-pregnant-women-in-china-2016-trend-and-spatial-analysis
#14
J R Jiang, Y B Zhou, H T Li, Y Q Gao, Y L Zhang, S S Luo, C Y Kang, J M Liu
Objective: To describe the spatial distribution characteristics of the HIV prevalence among pregnant women in mainland China in 2016, providing scientific evidence for the prevention of mother-to-child transmission of HIV. Methods: Data on pregnant women and those living with HIV in 2016 for all counties in mainland China is from the National Maternal & Child Health Statistics dataset. To obtain robust estimates, 2 964 counties were merged into 344 cities. Spatial autocorrelation analysis and trend analysis were performed based on the city-level dataset to detailedly describe the characteristics of the spatial distribution...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440128/-role-of-signaling-pathway-of-long-non-coding-rna-growth-arrest-specific-transcript-5-microrna-200c-3p-angiotensin-converting-enzyme-2-in-the-apoptosis-of-human-lung-epithelial-cell-a549-in-acute-respiratory-distress-syndrome
#15
H B Li, P P Zi, H J Shi, M Gao, R Q Sun
Objective: To investigate whether long non-coding RNA (lncRNA) growth arrest-specific transcript 5 (GAS5)/microRNA-200c-3p/angiotensin converting enzyme 2(ACE2) involved in the regulation of the apoptosis of human lung epithelial cell A549 in acute respiratory distress syndrome (ARDS). Methods: ARDS rat models were established and were divided into control, ARDS, ARDS+ pcDNA and ARDS+ pcDNA-GAS5 groups. Six hours after the establishment of ARDS rat model, arterial blood and lung tissues of the rats from the four groups were collected...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440127/-brachytherapy-treatment-planning-calculation-125-i-particle-esophageal-stent-dosimetric-study
#16
H T Sun, J J Wang, L Lin
Objective: To investigate the dosimetric distribution characteristics of (125)I seed stents with different seed spacing, diameter and length, as well as different (125)I seed activity. The dosimetry table of (125)I seed esophageal stent was derived to provide dosimetry for its clinical application. Methods: The self-expanding coated esophagus stent was designed to carry radioactive (125)I seeds with different length, diameter and seed spacing. A cylindrical organic glass model (Thickness 0.8 cm, diameter 20 cm, height 20 cm) was fixed vertically to a cylindrical organic glass containing a solid paraffin (analytical pure) solution...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440126/-effects-of-calcineurin-gene-silencing-on-the-remodeling-of-transient-outward-potassium-current-ionic-channel-in-hypertrophic-ventricular-myocytes-from-neonatal-rats
#17
J H He, L Yang, G L Xia, N Deng, Y Y Yang, Y Tian, Z N Fu, Y Q Huang
Objective: To investigate the effects of calcineurin gene silencing on the remodeling of transient outward potassium current (Ito) ionic channel and action potential duration (APD) in phenylephrine (PE)-induced hypertrophic ventricular myocytes from neonatal rats. Methods: The ventricular myocytes of 1-day-old Sprague-Dawley rats were isolated and cultured for 48 h. RNA interference mediated by adenovirus carrying short hairpin RNA was used to knock down the gene which encodes the beta subtype of calcineurin A subunit (CnAβ) and the cells were divided into 4 groups as Ad-null group, Ad-null+ PE group, Ad-CnAβshRNA1(A1) group and A1+ PE group, and then cultured for 48 h...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440125/-relevant-molecular-characteristics-analysis-on-malignant-transformation-of-interstitial-cells-induced-by-tumor-stem-cells-in-glioma-microenvironment
#18
X Y Ji, J Shi, X X Dai, Y J Sheng, Y P Xue, J C Liu, H H Cai, X L Dai, Y M Chen, Y S Zhang, Q Huang, J Dong
Objective: A variety of interstitial cells in tumor microenvironment (TME) based on glioma stem cells(GSC) have the function to promote malignant progression of tumors, but whether these interstitial cells have already undergone malignant transformation and their related molecular characteristics are still poorly understood. Methods: Human SU3-RFP glioma stem cells (GSC) stably transfected with red fluorescent protein (RFP) and interstitial cells from enhanced green fluorescent protein (EGFP) transgenic nude mice were co-cultured in vitro...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440124/-the-effect-of-pre-operation-125-i-seed-activity-measuring-on-dose-accuracy
#19
Z J Yang, H M Yu, Y S Liang, J X Zhao, Z Z Liu, H J Li, J Wang, H T Zhang
Objective: To measure the activity of (125)I seed and compare the dose difference of ten patients treated with seed implantation in pre-plan with actual seed activity and calibrate activity. Method: The activity of 100 seeds from company A and B was measured with a well-type ionization chamber 1 day before operation and named group A and B. The activity of two groups was compared and the error between actual and calibrate activity (22.2 MBq, group C) was calculated. Ten patients implanted with (125)I seeds from November 1 st to 30 th, 2017, solstice 30 were selected in Hebei General Hospital...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30440123/-the-correlation-between-the-cell-density-of-local-advanced-lung-cancer-tumor-and-the-adc-value-of-3-0-t-mri-diffusion-weighted-imaging
#20
Z X Lu, Z H Zhao, D D Wang, L Zhao, L M Yang, F Liu, Y N Huang
Objective: To investigate the correlation between tumorous cellular density (TCD) and apparent diffusion coefficient (ADC) of 3.0 T magnetic resonance diffusion weighted imaging (DWI) in local advanced lung cancer. Methods: From January 2015 to December 2017, a total of 59 patients with locally advanced lung cancer confirmed by pathology in Shaoxing People's Hospital who underwent DWI by 3.0 T magnetic resonance imaging were included.The ADC and TCD values of tumor were measured. The difference and correlation between ADC value and TCD in lung cancer were analyzed...
November 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
journal
journal
26446
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"