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Polimery W Medycynie

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https://www.readbyqxmd.com/read/29160630/synthetic-grafts-in-the-treatment-of-ruptured-anterior-cruciate-ligament-of-the-knee-joint
#1
REVIEW
Wojciech Satora, Aleksandra Królikowska, Andrzej Czamara, Paweł Reichert
The anterior cruciate ligament (ACL) is cited as the most frequently injured ligament in the knee. The standard treatment of ACL injury remains ligament reconstruction followed by a postoperative physiotherapeutic procedure. During the reconstruction, the torn ligament can be replaced with an autograft or an allograft. A synthetic ligament is also one of the available graft options. Synthetic grafts in ruptured ACL treatment have been used as scaffolds, stents, or prostheses. The story of using synthetic materials in ACL deficient knee treatment started in the beginning of the 20th century with the usage of silk and silver fibers...
January 2017: Polimery W Medycynie
https://www.readbyqxmd.com/read/29160629/chitosan-and-its-composites-properties-for-use-in-bone-substitution
#2
REVIEW
Marek Stępniewski, Jacek Martynkiewicz, Jerzy Gosk
For many years, research has been carried out on finding an ideal bone substitute. Chitosan (CTS) is a naturally occurring polysaccharide, obtained mainly from, inter alia, the shells of crustaceans. It is characterized by its high level of biocompatibility, biodegradability and antimicrobial properties as well as its support in the healing of wounds. Chitosan, due to its ability to form porous structures, can be used in the production of scaffolds used in the treatment of bone defects. There are numerous studies on the use of CTS in combination with other substances which aim to improve its biological and mechanical properties...
January 2017: Polimery W Medycynie
https://www.readbyqxmd.com/read/29160628/the-role-of-chitin-and-chitosan-in-peripheral-nerve-reconstruction
#3
REVIEW
Michał Bąk, Olga N Gutkowska, Ewa Wagner, Jerzy Gosk
Chitin is a natural polysaccharide commonly found in nature and chitosan is its partially deacetylated derivative. The properties of both biopolymers allow their wide use in medicine and various industries. This paper presents the possibilities offered by chitin and chitosan for the creation of neurotubes utilized in peripheral nerve repair procedures. In the initial part of this manuscript, experimental studies on both polysaccharides carried out by numerous authors have been presented and their results have been discussed...
January 2017: Polimery W Medycynie
https://www.readbyqxmd.com/read/29160627/native-and-microwave-modified-terminalia-mantaly-gums-as-sustained-release-and-bioadhesive-excipients-in-naproxen-matrix-tablet-formulations
#4
Michael Ayodele Odeniyi, Babatunde Mukhtar Oyedokun, Oluyemisi Adebowale Bamiro
BACKGROUND: Hydrophilic polymers provide a means of sustaining drug delivery. Native gums may be limited in function, but modification may improve their activity. OBJECTIVES: The aim of the study was to evaluate native and modified forms of Terminalia mantaly gum for their sustained-release and bioadhesive properties. MATERIAL AND METHODS: The native gum (NTM) was modified by microwave irradiation for 20 seconds (MTM20) and 60 seconds (MTM60) and characterized using microscopy, Fourier transform infrared spectroscopy (FTIR) and packing properties...
January 2017: Polimery W Medycynie
https://www.readbyqxmd.com/read/29160626/film-forming-properties-of-cissus-pulpunea-guill-and-perr-and-irvingia-gabonensis-o-rorke-gums
#5
Tolulope Omolola Ajala, Hope Idemudia Olaiya, Oluwatoyin Adepeju Odeku
BACKGROUND: Natural polymers such as gums have gained attention in drug delivery systems due to their availability, compatibility and degradation under natural and physiological conditions. OBJECTIVES: The aim of the present study was to investigate the film forming properties of gums obtained from the stem of Cissus polpunea (Guill and Perr) and the seed of Irvingia gabonensis (O'Rorke). MATERIAL AND METHODS: Gums were extracted from the relevant plant parts and characterized using functional, proximate and elemental properties...
January 2017: Polimery W Medycynie
https://www.readbyqxmd.com/read/29160625/evaluation-of-two-novel-plant-gums-for-bioadhesive-microsphere-and-sustained-release-formulations-of-metformin-hydrochloride
#6
John Oluwasogo Ayorinde, Michael Ayodele Odeniyi, Arvind K Bansal
BACKGROUND: The biological half life of metformin requires multiple doses which are associated with poor patient compliance. This justifies the need for a dosage form with reduced dosing frequency. OBJECTIVES: Gums from Enterolobium cyclocarpum and Cedrela odorata trees were evaluated in formulating bioadhesive microspheres containing metformin hydrochloride, for sustained drug release. Hydroxylpropylmethyl cellulose (HPMC) was the standard. MATERIAL AND METHODS: Microspheres were produced from formulations of API and either cedrela gum (FC), enterolobium gum (FE) or HPMC (FH), using a W/O solvent extraction technique...
January 2017: Polimery W Medycynie
https://www.readbyqxmd.com/read/29160624/buccal-patches-of-atenolol-formulated-using-fenugreek-trigonella-foenum-graecum-l-seed-mucilage
#7
Surya Narayan Ratha Adhikari, Satyabrata Panda
BACKGROUND: The use of mucoadhesive natural polymers in designing mucoadhesive patch systems has received much attention. OBJECTIVES: The study involved the development and evaluation of buccal patches of atenolol using fenugreek (Trigonella foenum-graecum L.) seed mucilage with hydroxylpropyl methyl cellulose (HPMC K4M) and a backing membrane (ethyl cellulose 5% w/v). MATERIAL AND METHODS: These atenolol-releasing buccal patches were prepared using a solvent casting technique...
January 2017: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397457/a-retrospective-evaluation-of-anatomical-reinsertion-of-the-distal-biceps-brachii-tendon-using-an-acl-tightrope%C3%A2-rt-with-a-titanium-cortical-button-and-ultra-high-molecular-weight-polyethylene-suture-a-preliminary-report
#8
Jarosław Witkowski, Maciej Kentel, Aleksandra Królikowska, Paweł Reichert
BACKGROUND: Various surgical techniques for treating distal biceps brachii tendon injury have been described, and to date there is no consensus regarding the preferred fixation method for the anatomic reinsertion of the ruptured tendon. OBJECTIVES: The aim of the study was to clinically and functionally evaluate the upper limb after surgical anatomic reinsertion of the distal biceps brachii tendon using an ACL TightRope® RT with a titanium cortical button and ultra high molecular weight polyethylene (UHMWPE) suture, and to assess postoperative complications...
July 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397456/postoperative-knee-joint-stability-following-anterior-cruciate-ligament-reconstruction-using-the-ligament-advanced-reinforcement-system
#9
Sebastian Krupa, Aleksandra Królikowska, Paweł Reichert
BACKGROUND: One of the goals of the synthetic materials used in knee joint reconstruction of the anterior cruciate ligament (ACL) is to improve the strength and stability of the graft immediately after the reconstruction. One of the synthetic grafts is a non-absorbable synthetic ligament device made of terephthalic polyethylene polyester fibers, the Ligament Advanced Reinforcement System (LARS). OBJECTIVES: The aim of the study was to assess postoperative knee joint stability in patients who had undergone ACL reconstruction using the LARS graft...
July 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397455/-application-of-synthetic-and-semisynthetic-polymers-kollidon-k30-and-hydroxypropylmethylcellulose-as-carriers-of-ketoprofen-in-solid-oral-prolonged-release-dosage-forms
#10
Wojciech Linka, Mateusz Kot, Michał Kołodziejczyk
BACKGROUND: One of the most important challenges of the modern technology of solid oral dosage forms is to increase the effectiveness of the drug, reduce side effects and improve the comfort of use. One way to obtain such effects are prolonged release dosage forms. OBJECTIVES: The aim of the study was to investigate the suitability of polymers (synthetic - Kollidon K30 and semisynthetic - hydroxypropyl methylcellulose), and calcium hydrogen phosphate dihydrate - as an inorganic insoluble filler - in the construction of the matrices of the solid oral dosage forms containing non-steroidal anti-inflammatory drugs (NSAIDs)...
July 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397454/histological-evaluation-of-the-local-soft-tissue-reaction-after-implanting-resorbable-and-non-resorbable-monofilament-fibers
#11
COMPARATIVE STUDY
Bogusława Żywicka, Maria Szymonowicz, Danuta Bryła, Zbigniew Rybak
BACKGROUND: The development of technologies and scientific disciplines connected with medical implantation devices is dynamically affecting modern treatments by contemporary medicine and veterinary medicine; it also entails a need to monitor their impact on living organisms. OBJECTIVES: The aim of the study was to conduct a comparative histological evaluation of the response of soft tissues after implanting monofilament fibers from resorbable glyconate and from non-resorbable polypropylene (PP) and polyamide (PA) in rats...
July 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397453/the-effect-of-curing-light-intensity-on-free-volume-size-in-some-dental-composites
#12
Mahdieh Shirazinia, Ali Akbar Mehmandoost-Khajeh-Dad, Vahid Dehghani, Jamshid Mehmandoost-Khajeh-Dad, Morteza Khaghani
BACKGROUND: Dental composite resins - reinforced polymers - are types of synthetic resins that are used in dentistry as restorative material or adhesives. The effect of curing-light intensity on free volume sizes of 4 commercial dental composites has been studied by means of the well-known positron annihilation lifetime spectroscopy technique. OBJECTIVES: The aim of the study was to compare the photosensitivity of 4 commercial dimethacrylate-based dental composites...
July 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397452/investigation-and-optimization-of-the-effect-of-polymers-on-drug-release-of-norfloxacin-from-floating-tablets
#13
Dipak D Gadade, Kalpana Sarda, Sadhana R Shahi
BACKGROUND: Norfloxacin is fluoroquinolone anti-infective used in the treatment of urinary tract infections, prostatitis, gonorrhea and genital tract infections. It has plasma half life of 3 to 4 h requiring multiple dosing in the treatment. Releaseretarding polymers can be used to modulate the drug release of norfloxacin. OBJECTIVES: The objective of this study was to investigate the effect of release-retarding polymers on the drug release of norfloxacin from floating tablets...
July 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397451/the-stress-relaxation-process-in-sutures-tied-with-a-surgeon-s-knot-in-a-simulated-biological-environment
#14
Aneta Liber-Kneć, Sylwia Łagan
BACKGROUND: The exact characteristics of sutures are not only the basis for selecting from among different types of suture, but also provide the necessary information for the design of new surgical sutures. Apart from information relating to the breaking load of a suture reported in pharmacopoeias, the viscoelastic properties of sutures can be an additional selection criterium - one that influences stitching quality, especially when there is a risk of wound dehiscence. OBJECTIVES: The aim of the study was to assess the stress relaxation process for 3 polymeric sutures in an environment simulating the conditions in a living organism and (for comparison) in room conditions...
July 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397425/polymers-as-carriers-of-gentamicin-in-traumatology-and-orthopedic-surgery-current-state-of-knowledge
#15
REVIEW
Jarosław Witkowski, Witold Wnukiewicz, Paweł Reichert
Osteomyelitis in patients undergoing surgery because of injuries and diseases of the musculoskeletal system is a serious clinical, economic and social problem. It is one of the greatest therapeutic challenges in traumatology and orthopedic surgery. To achieve the best results in the treatment of osteomyelitis, surgical debridement and intravenous antibiotic therapy is supported by local antibiotic delivery. Many different substances can be used as drug carriers. In this study we present and compare some polymers used as carriers of gentamicin...
January 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397424/chemical-substances-used-in-the-treatment-of-ganglions-located-in-the-hand-and-wrist
#16
REVIEW
Sebastian Kuliński, Olga Gutkowska, Jerzy Gosk
The aim of this work was to compare different chemical substances used in the treatment of ganglions located in the hand and wrist region. Their basic properties and mechanisms of action have been described. Moreover, the risks associated with the use of particular substances have been highlighted and potential complications connected with their administration have been discussed. On the basis of the available literature, the results of ganglion aspiration treatment followed by an injection of a chemical substance into the cyst cavity have been assessed...
January 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397423/corneal-cross-linking-an-example-of-photoinduced-polymerization-as-a-treatment-modality-in-keratoconus
#17
REVIEW
Magdalena Kubrak-Kisza, Krystian Jerzy Kisza, Marta Misiuk-Hojło
The cornea is one of the principal refractive elements in the human eye and plays a crucial role in the process of vision. Keratoconus is the most common corneal dystrophy, found mostly among young adults. It is characterized by a reduced number of collagen cross-links in the corneal stroma, resulting in reduced biomechanical stability and an abnormal shape of the cornea. These changes lead to progressive myopia, corneal thinning, central scarring and irregular astigmatism, causing severely impaired vision...
January 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397422/thermoplastic-elastomers-materials-for-heart-assist-devices
#18
REVIEW
Agnieszka Piegat, Mirosława El Fray
Heart assisting devices have become a standard element in clinical practice and provide support for the traditional methods of treating heart disease. Regardless of the construction of VAD (ventricular assist devices), there are crucial requirements that have to be met by the construction materials: high purity, desired physical, chemical and mechanical properties, easy fabrication and high stability and susceptibility to sterilization. They must not cause thrombosis, destroy cellular elements, alter plasma protein, destroy enzymes, deplete electrolytes, cause immune response and cancer, and must not produce toxic and allergic reactions, when they are applied in direct contact with biological tissues and fluids...
January 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397421/-methods-of-reduction-of-warm-ischemic-time-in-kidney-transplantation-and-their-role-of-early-and-late-outcomes
#19
REVIEW
Agnieszka Lepiesza, Paweł Chudoba, Dorota Kamińska, Artur Pupka, Patrycja Zaleska
Kidney is the organ transplanted most often. An increase in the number of expanded criteria donors (ECD) has been observed for years, and consequently the condition of transplanted organs worsened. In recent years, the possibility to recover organs from donors after cardiac death (DCD) became legally available in Poland, which will result in the increase of donors. Every DCD donor is at the same time ECD donor. One of the most important challenges the transplantology has to face is the improvement of the quality of transplanted organs...
January 2016: Polimery W Medycynie
https://www.readbyqxmd.com/read/28397420/-vascular-system-infections-characteristics-risk-factors-prevention-methods-and-economic-impact
#20
REVIEW
Benita Wiatrak, Ewa Karuga-Kuźniewska, Arleta Staszuk, Justyna Gabryś, Ryszard Tadeusiewicz
One of the main problems of modern medicine are infections. They can be divided into local and general (depending on infected tissues and/or organs) or hospital and community-acquired infections (depending on the location and source of infection). The occurrence of infection reduces the ability for quick recovery, and in case of complications the ability to continue professional activity. Bacteria can be present in the vascular system causing vein, artery, capillary infection or blood infection (bacteremia)...
January 2016: Polimery W Medycynie
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