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Transactions of the American Clinical and Climatological Association

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https://www.readbyqxmd.com/read/30166739/present-members
#1
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2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166738/deceased-members-1884-through-2017
#2
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2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166737/acca-presidents-past-and-present-and-spouses
#3
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2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166736/american-clinical-and-climatological-association-meeting-locations-1884-2017
#4
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166735/constitution-and-by-laws
#5
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166734/former-officers-1884-through-2017
#6
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166733/instructions-to-authors-transactions-of-the-american-clinical-and-climatological-association
#7
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166732/recorder-s-report
#8
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166731/accountants-compilation-report
#9
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166730/secretary-treasurer-s-report
#10
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166729/officers-and-council-2018
#11
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166728/officers-and-council-2017
#12
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166726/an-outcomes-based-approach-across-the-medical-education-continuum
#13
Mark E Rosenberg
The medical education continuum spans undergraduate medical education (i.e., medical school), graduate medical education (i.e., residency and fellowship), and continuing medical education. This article provides three examples across the medical education and practice continuum where an outcomes-based approach is being used. By focusing on outcomes instead of process, a more predictable product of undergraduate medical education will be a medical student capable on day 1 of performing the work required of residency...
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166725/in-my-own-words-the-value-of-storytelling-to-shape-the-academic-medicine-journey
#14
Sherita Hill Golden
As young physicians, we are trained to listen to our patients as they relay a set of signs, symptoms, and feelings to us, and then to translate their stories into a diagnosis and treatment plan that improves their health status and overall quality of life. The art of storytelling is crucial in disseminating diverse and innovative perspectives in academic medicine. First, stories from patients play a pivotal role in defining new areas of research focus for building the careers of physician-scientists, allowing them to take full advantage of the depth and breadth of their clinical and research skills...
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166724/the-future-of-cardiovascular-care-from-affordable-care-to-the-academic-medical-center
#15
Marvin A Konstam
We are presently seeing exponential advances in medical knowledge and development of therapeutic and diagnostic tools. We have also begun to experience an historic restructuring of our health care system. But health care costs continue to rise, disparities persist, and the chaotic, disjointed, and often thoughtless discourse in Washington threatens to roll back the prior advances. Improvement in patient care will be severely stymied if the threats to academic medical centers are not countered. This paper will explore our present state through the lens of cardiovascular care...
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166723/efficacy-to-effectiveness-clinical-trials
#16
Harry P Selker, Sheeona Gorman, Kenneth I Kaitin
Efficacy trials, which assess treatments in optimally selected patients under advantageous conditions for relatively short time periods, are necessary to gain regulatory approval for marketing. In contrast, effectiveness trials, which test treatments across a spectrum of patients in real-world conditions with follow-up periods that match typical treatment regimens, provide critical information on drug effects in those patients who may ultimately receive the treatment. We previously proposed a study design that integrates efficacy and effectiveness trials into a 2-component "efficacy-to-effectiveness (E2E) trial," in which if the initial efficacy trial component is positive, then the trial immediately and seamlessly transitions to the effectiveness trial component...
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166722/mitochondrial-dynamics-and-metabolic-regulation-in-cardiac-and-skeletal-muscle
#17
E Dale Abel
Mitochondria are the metabolic powerhouses of cells. In addition to generating adenosine triphosphate (ATP), they play important roles in cell survival pathways such as apoptosis and necrosis. Mitochondrial size and shape are dynamically regulated by a process known as mitochondrial dynamics. The significance of this process in metabolically active cells such as skeletal and cardiac muscle are only now beginning to be elucidated. In cardiac muscle, mitochondrial dynamics plays an important role in mitochondrial quality control and defects in regulatory pathways that govern these processes and leads to heart failure...
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166721/the-jeremiah-metzger-lecture-novel-therapeutic-strategies-of-allergic-and-immunologic-disorders
#18
Ronald G Crystal, Odelya E Pagovich
Advances in understanding the immunological basis and mechanisms underlying allergic and immunologic disorders have led to effective but costly long-term and repetitive biologic therapies. Gene therapy is a rapidly advancing technology, in which a single administration of an adeno-associated virus encoding the therapeutic protein or monoclonal antibody may provide effective long-term therapy for allergic and immunologic disorders. In this review, we summarize the recent studies from our laboratory developing gene therapy strategies to treat hereditary angioedema and peanut allergy...
2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166720/jeremiah-metzger-lectures
#19
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2018: Transactions of the American Clinical and Climatological Association
https://www.readbyqxmd.com/read/30166719/the-jeremiah-metzger-lecture
#20
(no author information available yet)
No abstract text is available yet for this article.
2018: Transactions of the American Clinical and Climatological Association
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