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Revista do Instituto de Medicina Tropical de São Paulo

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https://www.readbyqxmd.com/read/29116294/secondary-syphilis-presenting-as-leucoderma-syphiliticum-case-report-and-review
#1
Walter de Araujo Eyer-Silva, Carlos José Martins, Guilherme Almeida Rosa da Silva, Giresse Acakpovi, Jorge Francisco da Cunha Pinto
Leucoderma syphiliticum (LS), originally described as syphilide pigmentaire, encompasses a spectrum of dyschromic lesions that emerge during the course of secondary syphilis. Very few case reports are available in modern biomedical databases. We present the case of a 57-year-old HIV-infected male patient who presented with several round to oval, non-scaling, slightly raised and well-demarcated hypochromic lesions scattered over the trunk, abdomen, dorsum, and arms. Prior non-treponemal tests were negative for syphilis, but novel studies yielded positive results at high titers...
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29116293/antioxidant-effect-of-morus-nigra-on-chagas-disease-progression
#2
Michelly Cristina Montenote, Vithor Zuccaro Wajsman, Yoichi Takaki Konno, Paulo César Ferreira, Regildo Márcio Gonçalves Silva, Altino Luiz Silva Therezo, Luciana Pereira Silva, Luciamáre Perinetti Alves Martins
Considering the widespread popular use of Morus nigra and the amount of scientific information on its antioxidant and anti-inflammatory activity, the effectiveness of this phytotherapeutic compound in the parasitemia progression during the acute phase of Chagas disease and its role in the development of the inflammatory process as well as its effects on the oxidative damage in the chronic phase of infection were evaluated. Thus, 96 male Swiss mice were randomly divided into eight groups, four groups were uninfected controls, and four groups were intraperitoneally infected with 5...
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29116292/first-isolation-report-of-arcobacter-cryaerophilus-from-a-human-diarrhea-sample-in-costa-rica
#3
Karol Barboza, Zaida Cubillo, Eduardo Castro, Mauricio Redondo-Solano, Heriberto Fernández-Jaramillo, María Laura Arias Echandi
Arcobacter cryaerophilus is an emerging enteropathogen and potential zoonotic agent transmitted by food and water. In Costa Rica, this bacterium has not been associated with cases of human gastroenteritis, even though it has been isolated from farm animals, especially poultry. This paper reports the first isolation of A. cryaerophilus from a human case of bloody watery diarrhea and the virulence genes associated with this isolate.
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29116291/analysis-of-dengue-cases-according-to-clinical-severity-s%C3%A3-o-lu%C3%A3-s-maranh%C3%A3-o-brazil
#4
José de Jesus Dias, Maria Dos Remédios Freitas Carvalho Branco, Rejane Christine de Sousa Queiroz, Alcione Miranda Dos Santos, Emnielle Pinto Borges Moreira, Maria do Socorro da Silva
Severe dengue cases have increased in Brazil since 2001, with the first records in Maranhão dating back to 2002. The aim of this study was to determine the prevalence of severe dengue cases by age group and the possible risk factors. This was a study of secondary data on dengue in residents of São Luís, Maranhão, Brazil, using probable cases notified to the National Mandatory Reporting System (SINAN) from 2002 to 2011. The diagnosis and classification of dengue were based on the Brazilian Ministry of Health criteria: dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue fever with complications (DWC)...
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29116290/drug-resistance-ampc-%C3%AE-lactamase-and-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-isolated-from-fish-and-shrimp
#5
Marília Viana Albuquerque de Almeida, Ítalo Mendes Cangussú, Antonia Leonadia Siqueira de Carvalho, Izabelly Linhares Ponte Brito, Renata Albuquerque Costa
The present study aims to detect the production of extended-spectrum beta-lactamases (ESBL) by enterobacteria isolated from samples of fresh shrimp and fish obtained from the retail trade of the city of Sobral, Ceará State, Brazil. All bacterial isolates were submitted to identification and antimicrobial susceptibility testing using aminopenicillin, beta-lactamase inhibitors, carbapenem, 1st, 2nd, 3rd and 4th generation cephalosporins, and monobactam. Three types of beta-lactamases - ESBL, AmpC and KPC - were investigated...
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29116289/difficulties-in-the-revaccination-program-of-hematopoietic-stem-cell-transplantation-recipients
#6
Paula Moreira da Silva, Élen Monteiro da Silva, Anderson João Simioni, Mair Pedro de Souza, Vergílio Antonio Rensi Colturato, Clarisse Martins Machado
Hematopoietic stem cell transplant (HSCT) recipients should be routinely revaccinated after transplantation. We evaluated the difficulties met in the revaccination program and how a prospective and tailored follow-up could help to overcome these obstacles. HSCT recipients (n=122) were prospectively followed up and categorized into Group 1 (n=72), recipients who had already started the revaccination program, and Group 2 (n=50), recipients starting their vaccines. Whenever a difficulty was reported, interventions and subsequent evaluations were performed...
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29116288/epidemiological-surveillance-of-land-borders-in-north-and-south-america-a-case-study
#7
Robson Bruniera-Oliveira, Marco Aurélio Pereira Horta, Aiden Varan, Sonia Montiel, Eduardo Hage Carmo, Stephen H Waterman, José Fernando de Souza Verani
This study aims to analyze the different binational/multinational activities, programs, and structures taking place on the borders of Brazil and the U.S. between 2013 and 2015. A descriptive exploratory study of two border epidemiological surveillance (BES) systems has been performed. Two approaches were used to collect data: i) technical visits to the facilities involved with border surveillance and application of a questionnaire survey; ii) application of an online questionnaire survey. It was identified that, for both surveillance systems, more than 55% of the technicians had realized that the BES and its activities have high priority...
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29116287/peginterferon-still-has-a-place-in-the-treatment-of-hepatitis-c-caused-by-genotype-3-virus
#8
Aline Vitali Grando, Paulo Roberto Abrão Ferreira, Mário Guimarães Pessôa, Daniel Ferraz de Campos Mazo, Carlos Eduardo Brandão-Mello, Tânia Reuter, Ana de Lourdes Candolo Martinelli, Mário Peribanez Gonzalez, Ana Catharina Seixas-Santos Nastri, Aléia Faustina Campos, Max Igor Banks Ferreira Lopes, José David Urbaez Brito, Maria Cássia Mendes-Corrêa
Despite recent advances in therapy for chronic hepatitis C (CHC), the disease caused by genotype 3 virus (GEN3) is still considered a treatment challenge in certain patient subgroups. The aim of this retrospective study was to evaluate the effectiveness and safety of the peginterferon (Peg-IFN) and ribavirin (RBV) combination treatment for GEN3/CHC patients, and to evaluate sustained virological response (SVR) indicators and early treatment interruption due to serious adverse events (SAE). This was a retrospective observational study of GEN3/CHC patients, co-infected or not by HIV and treated with Peg-IFN/RBV in nine Brazilian healthcare centers...
November 6, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28876418/a-conventional-pcr-for-differentiating-common-taeniid-species-of-dogs-based-on-in-silico-microsatellite-analysis
#9
Saeedeh Shamsaddini, Mohammad Ali Mohammadi, Seyed Reza Mirbadie, Sima Rostami, Mansoureh Dehghani, Balal Sadeghi, Majid Fasihi Harandi
Canine taeniids are among the major tapeworms with remarkable medical and economic significance. Reliable diagnosis and differentiation of dog taeniids using simple and sensitive tools are of paramount importance for establishing an efficient surveillance system. Microsatellites as abundant unique tandem repeats of short DNA motifs are useful genetic markers for molecular epidemiological studies. The purpose of the present study was to find a primer pair for rapid differentiation of major tapeworms of dogs, Taenia hydatigena, T...
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28876417/prospective-study-of-patients-with-persistent-symptoms-of-dengue-in-brazil
#10
Luciana de Almeida Silva Teixeira, Fabiana Prado Dos Santos Nogueira, Gabriel Antonio Nogueira Nascentes
Dengue is an arboviral infection clinically recognized as an acute and self-limited disease. Persistence of dengue symptoms is known, but it has been little studied. The aim of this study was to characterize persistent symptoms in 113 patients with dengue followed up clinically and by laboratory testing at a tertiary hospital. Symptoms that persisted for more than 14 days were observed in 61 (54.0%) patients, and six (6.2%) of them had symptoms for 6 months or more. The persistent symptoms identified were myalgia, weakness, hair loss, memory loss, reduced resistance to physical effort, headache, reasoning problems, arthralgia, sleepiness- and emotional lability...
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28876416/considerations-of-potential-vectors-and-animal-reservoirs-in-an-emerging-cutaneous-leishmaniasis-area-in-s%C3%A3-o-domingos-ranch-paran%C3%A3-state-in-southearn-brazil
#11
Norberto Assis Membrive, Flora Hisatugo, Thaís Gomes Verzignassi Silveira, Jorge Juarez Vieira Teixeira, Kárin Rosi Reinhold-Castro, Ueslei Teodoro
The aim of this study was to better understand the dynamics of Leishmania sand flies and reservoirs in São Domingos ranch, Arapongas municipality, Paraná State, an anthropic environment in an endemic area of cutaneous leishmaniasis (CL). Sand flies were collected in wild animal burrows, residences and in the forest, with Falcão light trap (FA), Shannon trap (SH) and quadrangular pyramidal trap (QP). The search for Leishmania was made on sand flies, biological samples of wild rodents and dogs using PCR and culture; while parasite direct search (DS) was carried out on animal skin lesions; infection of gold hamsters; and indirect immunofluorescence (IIF) test in dog blood samples...
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28876415/chronic-lymphadenopathy-caused-by-a-brazilian-strain-of-bartonella-henselae
#12
Paulo Eduardo Neves Ferreira Velho, Marina Rovani Drummond, Marcio Antonio Haro Adad, Maria Letícia Cintra, Stanley Sowy, Pedro Paulo Vissotto de Paiva Diniz
Bartonella henselae is a relevant causative agent of bartonelloses in humans. We described an immunocompetent patient with clinical manifestation of chronic cervical lymphadenopathy after a cat-scratch in her forearm. This case shows B. henselae infection persistence even after prolonged antibiotic treatment.
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28902298/nursing-infant-with-acquired-toxoplasmosis-in-the-first-months-of-life-a-case-report
#13
Hanstter Hallison Alves Rezende, Heloísa Ribeiro Storchilo, Jaqueline Ataíde Silva Lima, Antônio Roberto Gomes, Taynara Cristina Gomes, Jéssica Yonara de Souza, Mariza Martins Avelino, Waldemar Naves do Amaral, Marina Clare Vinaud, Ana Maria de Castro
Toxoplasmosis is caused by Toxoplasma gondii and the probability of this infection occurring in the first months of life is usually low because its transmission is related to eating habits. A 6-month-old nursing infant was diagnosed with acute toxoplasmosis, which was identified through anti- T. gondii IgA, IgM and low-avidity IgG serologic assays, polymerase chain reaction (PCR) and mouse bioassay test although its mother was seronegative. This serological divergence between mother and child led us to interview the mother regarding epidemiological factors...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28902297/the-influence-of-serial-fecal-sampling-on-the-diagnosis-of-giardiasis-in-humans-dogs-and-cats
#14
Flávia Fernandes de Mendonça Uchôa, Adriana Pittella Sudré, Daniel de Barros Macieira, Nádia Regina Pereira Almosny
Giardia infection is a common clinical problem in humans and pets. The diagnosis of giardiasis is challenging as hosts intermittently excrete protozoan cysts in their feces. In the present study, we comparatively evaluated two methods of serial fecal sampling in humans, dogs, and cats from Rio de Janeiro, Brazil. The Faust et al. technique was used to examine fecal specimens collected in triplicate from 133 patients (52 humans, 60 dogs, and 21 cats). Specimens from 74 patients were received from the group assigned to carry out sampling on consecutive days - 34 humans, 35 dogs, and 5 cats, and specimens from 59 patients were received from the group assigned to carry out sampling on non-consecutive, separate days - 18 human beings, 25 dogs, and 16 cats...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28902296/an-unusual-case-of-bacillary-angiomatosis-in-the-oral-cavity-of-an-aids-patient-who-had-no-concomitant-tegumentary-lesions-case-report-and-review
#15
Walter de Araujo Eyer-Silva, Pedro Eugênio Mendes Arena Soares, Marcelo Costa Velho Mendes de Azevedo, Guilherme Almeida Rosa da Silva, Dario José Hart Pontes Signorini, Rogerio Neves-Motta, Jorge Francisco da Cunha Pinto, Lívia Machado Moura, Rodrigo Panno Basílio-de-Oliveira, Luciana Ferreira de Araujo, Alexsandra Rodrigues de Mendonça Favacho, Elba Regina Sampaio Lemos
Bacillary angiomatosis (BA) is an angioproliferative disease of immunocompromised patients that usually presents as vascular tumors in the skin and subcutaneous tissues. It is caused by chronic infections with either Bartonella henselae or B. quintana. Oral cavity BA is exceedingly rare and even rarer without simultaneous cutaneous disease. We report herein the case of a 51-year-old HIV-infected man who presented severe odynophagia and an eroded lesion on the hard palate that progressed to an oronasal fistula...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28902295/sandfly-fauna-diptera-psychodidae-in-an-urban-area-central-west-of-brazil
#16
Wagner de Souza Fernandes, Leandro Machado Borges, Aline Etelvina Casaril, Everton Falcão de Oliveira, Jucelei de Oliveira Moura Infran, Eliane Mattos Piranda, Elisa Teruya Oshiro, Suellem Petilim Gomes, Alessandra Gutierrez de Oliveira
Biological and ecological relations among vectors and their pathogens are important to understand the epidemiology of vector-borne diseases. Camapuã is an endemic area for visceral and tegumentary leishmaniasis. The aim of this study was to characterize the sandfly fauna present in Camapuã , MS, Brazil. Sand flies were collected every fortnight from May 2014 to April 2015 using automatic light traps in the domicile and peridomicile of twelve neighborhoods and forest. The collected specimens were identified based on morphology according to the valid identification keys...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28902294/oral-health-conditions-in-leprosy-cases-in-hyperendemic-area-of-the-brazilian-amazon
#17
Zilanda Martins de Almeida, Alberto Novaes Ramos, Marcos Túlio Raposo, Francisco Rogerlândio Martins-Melo, Cidia Vasconcellos
Leprosy is a hyperendemic chronic condition in the Rondônia State . Despite the significant impact of oral health on the quality of life and clinical evolution of leprosy patients, systematic evaluation of oral health status has been neglected. To analyze the dental-clinical profile, self-perceived oral health and dental health service access of leprosy cases in the municipality of Cacoal in Rondônia State , North Brazil, from 2001 to 2012. A descriptive, cross-sectional study design was performed based on dental evaluation and standardized structured instruments...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28902293/characterization-of-leishmania-l-infantum-chagasi-in-visceral-leishmaniasis-associated-with-hiv-co-infection-in-northeastern-brazil
#18
Elaine Cristina Bomfim de Lima, Walter Lins Barbosa, Maria Edileuza Felinto de Brito, Fábio Lopes de Melo, Sinval Pinto Brandão, Zulma Maria de Medeiros
Visceral leishmaniasis, associated with HIV/AIDS coinfection, is becoming a more aggressive disease, complicating an accurate prognosis. A 21-year-old HIV-positive female presenting with clinical features of visceral leishmaniasis was enrolled in this study. Bone marrow cytology, Novy-MacNeal-Nicolle culture and kDNA PCR of peripheral blood were all positive. Typing methods, multilocus enzyme electrophoresis and ITS1-RFLP PCR of peripheral blood confirmed infection by Leishmania (L.) infantum chagasi . PCR has proved to be safer and more affordable than other characterization methods; ITS1-RFLP PCR can diagnose and type Leishmania spp...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28793027/oviposition-behavior-of-haemagogus-leucocelaenus-diptera-culicidae-a-vector-of-wild-yellow-fever-in-brazil
#19
Aline Tátila-Ferreira, Daniele de Aguiar Maia, Filipe Vieira Santos de Abreu, William Costa Rodrigues, Jeronimo Alencar
Haemagogus leucocelaenus, which is considered a major vector of wild yellow fever, exhibits acrodendrophilic habits and mainly deposits its eggs in treeholes and bamboo internodes. The selection of nursery sites is essential in the life history and reproductive success of mosquitoes. The present work investigated the preferred oviposition height and period of Hg. leucocelaenus in an Atlantic forest area in Rio de Janeiro. Sampling was performed using oviposition traps that were placed on plant material at 0, 2, 4, 6, and 8 m above the ground, from August 2015 to July 2016...
August 7, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28793026/epidemiological-study-of-scorpion-stings-in-the-rio-grande-do-norte-state-northeastern-brazil
#20
Kaliany Adja Medeiros de Araújo, Aluska Vieira Tavares, Michael Radan de Vasconcelos Marques, Alecxandro Alves Vieira, Renner de Souza Leite
This communication is a retrospective epidemiological study of the scorpion sting cases recorded from 2007 to 2014 in the Rio Grande do Norte State, Northeastern Brazil. The data was collected from the Injury Notification Information System database of the Health Department of Rio Grande do Norte State. A total of 20,555 cases were studied. The cases were distributed over all months of the period studied and occurred mainly in urban areas. Victims were predominantly 20-29 year-old women. Most victims were stung on the foot and received medical care within 1-3 h after being stung...
August 7, 2017: Revista do Instituto de Medicina Tropical de São Paulo
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