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Revista do Instituto de Medicina Tropical de São Paulo

Beatriz Teixeira Gomes da Silva, Aline Moreira de Souza, Sabrina Destri Emmerick Campos, Elba Regina Sampaio de Lemos, Alexsandra Rodrigues de Mendonça Favacho, Nádia Regina Pereira Almosny
No abstract text is available yet for this article.
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
Natane Barbosa Barcelos, Lorena de Freitas E Silva, Regyane Ferreira Guimarães Dias, Hélio Ranes de Menezes Filho, Rosângela Maria Rodrigues
Patients infected with the Human Immunodeficiency Virus (HIV) often have opportunistic infections, among which strongyloidiasis and coccidiosis are the most common parasitic infections that aggravate their health status. This study examined the prevalence of intestinal parasites, particularly of Strongyloides stercoralis and intestinal coccidia in patients with the Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) who were treated at the Specialized Assistance Service (SAE) of Jataí, State of Goiás, Brazil, and analyzed its correlation with clinical, laboratory, and socio-epidemiological parameters...
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
João Gabriel Guimarães Luz, Danilo Bueno Naves, Amanda Gabriela de Carvalho, Gilvani Alves Meira, João Victor Leite Dias, Cor Jesus Fernandes Fontes
The Brazilian municipality of Rondonópolis, Mato Grosso State, represents an important visceral leishmaniasis (VL) endemic area. This study described epidemiological and clinical aspects of the occurrence, VL/HIV coinfection and lethality related to VL in Rondonópolis. Data from autochthonous cases reported between 2011 and 2016 were obtained from official information systems. During this period, 81 autochthonous cases were reported, with decreasing incidence through 2016. Contrastingly, the lethality rate was 8...
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
Guilherme Almeida Rosa da Silva, Heloisa Loureiro de Sá Neves Motta, Erik Friedrich Alex de Souza, Pedro Afonso Nogueira Moises Cardoso, José Henrique Pilotto, Walter Araujo Eyer-Silva, Luiz Cláudio Pereira Ribeiro, Mônica Soares Dos Santos, Marcelo Costa Velho Mendes de Azevedo, Jorge Francisco da Cunha Pinto, Rogerio Neves Motta, Fernando Raphael de Almeida Ferry
OBJECTIVES: The increase in HIV transmissibility in non-ulcerative sexually transmitted infection is already well-established. It is estimated that symptomatic carriers of N. gonorrhoeae and C. trachomatis have a relative risk of 4.8-fold and 3.6-fold, respectively, for the sexual acquisition of HIV. This type of evaluation for asymptomatic urethritis is necessary to reinforce strategies to combat HIV transmission. This study aims to assess the prevalence of patients with asymptomatic urethritis among men diagnosed with HIV-1 and determine the risk factors associated with this infection...
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
Imelda Menchaca-Armenta, Moisés Ocampo-Torres, Arnulfo Hernández-Gómez, Karen Zamora-Cerritos
Diseases caused by viruses such as dengue, chikungunya and zika are mosquito-borne diseases transmitted by Aedes aegypti. We performed a cross-sectional study of healthcare personnel and the general population using questionnaires to identify the level of knowledge, attitudes and practices, and risk perception for dengue, chikungunya and zika. A total of 248 questionnaires were applied, 63.3% to healthcare personnel and 36.7% to the general population. Of the healthcare personnel, 53% were men, and in the general population 74% were women...
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
Polianna Lemos Moura Moreira Albuquerque, Karla do Nascimento Magalhaes, Tamiris de Castro Sales, José Hícaro Hellano Gonçalves Lima Paiva, Elizabeth de Francesco Daher, Geraldo Bezerra da Silva Junior
Despite the high number of accidents due to scorpion stings in Brazil, severe cases in adults are seldomly reported. In the Northeast region of Brazil, Tityus stigmurus is the most prevalent species. A 69 year-old woman who was stung by a scorpion attended the emergency room 5 hours after envenomation. She got worse due to abdominal pain. Clinical findings were concordant with class III scorpion envenomation (major systemic manifestations), complicated by acute kidney injury and acute pancreatitis. Intensive supportive therapy was adopted...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Maria Beatriz Pena E Silva Leite Nacife, Liliane Maria Vidal Siqueira, Rafael Martins, Valeska Natiely Vianna, Keila Furbino Barbosa, Cássio Zumerle Masioli, Jaime Costa da Silva, George Luiz Lins Machado-Coelho
Intestinal parasitic infections are a common health problem among Amerindian populations and schistosomiasis represents one of the most prevalent diseases in Maxakali people. The Kato-Katz is the diagnostic method recommended by WHO for epidemiological studies; however, one of the technique's limitations is the failure to detect parasites in individuals with low parasite load. The aim of this study was to establish the prevalence of Schistosoma mansoni in indigenous Maxakali villages, evaluating the TF-Test® performance for diagnosis compared to the Kato-Katz technique...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Lenyta Oliveira Gomes, Marina Rodrigues Teixeira, Júnior André da Rosa, Alberi Adolfo Feltrin, João Paulo V Rodrigues, Mariane D'Avila Vecchi, Jane Meire M Carneiro, Lúcia de Araújo C B Noblat, Silvana Gama F Chachá, Ana de Lourdes C Martinelli, Leonardo Regis L Pereira, Marysabel Pinto T Silveira, Carine Raquel Blatt, Mareni Rocha Farias
In 2012, the first-generation protease inhibitors telaprevir (TVR) and boceprevir (BOC) were introduced in the Brazilian health system for treatment of chronic hepatitis C, after their approval by the National Committee for Health Technology Incorporation (CONITEC). However, these medicines were discontinued in 2015. The short period of use in therapy and their high cost require a discussion about the consequences for patients and for the health system of the early incorporation of new therapies. The article presents a qualitative analysis of the incorporation process of both medications in Brazil and the results of a multicenter study that included patients treated with BOC or TVR between January 2011 and December 2015 in five Brazilian cities...
2018: Revista do Instituto de Medicina Tropical de São Paulo
(no author information available yet)
No abstract text is available yet for this article.
2018: Revista do Instituto de Medicina Tropical de São Paulo
Emanuelle Malzac Freire de Santana, Karen Krystine Gonçalves de Brito, Ester Missias Vilaverde Antas, Jordana de Almeida Nogueira, Oriana Deyze Correia Paiva Leadebal, Mirian Alves da Silva, Marta Miriam Lopes Costa, Maria Júlia Guimarães Oliveira Soares
Hansen's disease is probably the human disease that causes more damage. The aim of this study was to investigate the association between the occurrence of the association of grade 1 and 2 physical disabilities in Hansen's disease, as well as implications of joint analysis and strength of association with independent demographic and clinical variables. This is a quantitative, descriptive, retrospective, population-based and documentary study developed from 2009 to 2014 in a Hansen's disease reference center in Joao Pessoa, PB...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Kerla Joeline Lima Monteiro, Elis Regina Chaves Dos Reis, Beatriz Coronato Nunes, Lauren Hubert Jaeger, Deiviane Aparecida Calegar, Jéssica Pereira Dos Santos, Alexander de Oliveira Maia, Samanta Cristina das Chagas Xavier, Márcio Neves Bóia, Filipe Anibal Carvalho-Costa
This study aims to describe the prevalence, distribution, and factors associated with soil-transmitted helminthiases (STHs) in rural localities in Piaui, Brazil. Two cross-sectional surveys (n=605 subjects; 172 families) were carried out in order to obtain socio-demographic, anthropometric, spatial and parasitological data. Parasites were evaluated using Kato-Katz and centrifugal sedimentation techniques. Eggs were measured to assess infection with zoonotic Strongylida parasites. Kernel maps were constructed with Q-GIS...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Júlia Silveira Vianna, Ivy Bastos Ramis, Daniela Fernandes Ramos, Otávio Leite Gastal, Renato Azevedo da Silva, Carla Vitola Gonçalves, Pedro Eduardo Almeida da Silva
In this study, we evaluated the mutations of Helicobacter pylori associated with resistance to clarithromycin and levofloxacin. Furthermore, based on the proposed interaction between antimicrobial resistance and pathogenicity, we correlated the mutation profiles of the strains with the presence of the pathogenicity gene cagA. We analyzed 80 gastric biopsy specimens from H. pylori-infected patients for point mutations in the 23S rRNA gene region and in the gyrA gene, which are related to clarithromycin and levofloxacin resistance, respectively, and investigated the presence of the cagA gene in these strains...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Adelita Campos Araújo, Marcos Marreiro Villela, Ângela Sena-Lopes, Nara Amélia da Rosa Farias, Laura Maria Jorge de Faria, Luciana Farias da Costa Avila, Maria Elisabeth Aires Berne, Sibele Borsuk
Due to the growing population of pets, especially homeless dogs and cats, zoonoses still represent a significant public health problem. Toxoplasma gondii and Toxocara spp. are epidemiologically important zoonotic agents as they are etiological factors of human toxoplasmosis and toxocariasis, respectively. These parasites remain neglected even though they are substantially prevalent in rural areas. The aim of this study was to investigate T. gondii and T. canis seroprevalence and risk factors of seropositivity in a rural population in Pelotas municipality, Brazil...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Daniel Pagotto Vendrami, Mauro Toledo Marrelli, Marcos Takashi Obara, José Maria Soares Barata, Walter Ceretti-Junior
This article reports a list with 912 specimens of the subfamily Triatominae deposited in the Entomological Collection of the Faculty of Public Health of the University of Sao Paulo. The collection is composed of 1 holotype, 3 alotypes, 15 paralectotypes, 77 paratypes, distributed in 5 tribes and 12 genera: Tribus Alberprosenini: genus Alberprosenia Martinez & Carcavallo, 1977; Tribus Bolboderini: genus Microtriatoma Prosen & Martinez, 1952; Tribus Cavernicolini: genus Cavernicola Barber, 1937; Tribus Rhodnini: genus Psammolestes Bergroth, 1941; genus Rhodnius Stal, 1859; Tribus Triatomini: genus Dipetalogaster Usinger 1939; genus Eratyrus Stal 1859; genus Hermanlentia Jurberg & Galvão, 1997; genus Linshcosteus Distant, 1904; 1944; genus Panstrongylus Berg 1879; genus Paratriatoma Barber 1938; genus Triatoma Laporte 1833...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Thales De Brito, Ana Maria Gonçalves da Silva, Patrícia Antonia Estima Abreu
Leptospirosis is an acute bacterial septicemic febrile disease caused by pathogenic leptospires, which affect humans and animals in all parts of the world. Transmission can occur by direct contact with infected animals or, more commonly, through indirect contact with water or soil contaminated with urine from infected animals. Leptospires enter the body by penetrating mucous membranes or skin abrasions and disseminate through the hematogenic route. In humans, leptospirosis may cause a wide spectrum of symptoms...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Stefan Vilges de Oliveira, Raylene Medeiros Ferreira Costa, Geane Ferreira, Simone Valéria Costa Pereira, Marinete Amorim, Maria Fernanda Melo Monteiro, Leucio Câmara Alves, Gilberto Salles Gazeta
Spotted fevers are diseases caused by bacterial agents belonging to the spotted-fever (SF) group of the genus Rickettsia. The first documented case of SF in Pernambuco State, Northeast Brazil, was reported here. Also, it is the first case described of fatal SF in Northeast region of Brazil. The patient was a resident of Arcoverde municipality and the probable site of infection lies in Sertania municipality, both in Pernambuco State, a semi-arid region of Brazil. The patient had not visited other areas where SF is endemic...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Rachana Bhattarai, Hélène Carabin, Jose Flores-Rivera, Teresa Corona, Jefferson V Proaño, Ana Flisser, Christine M Budke
The objective of this study was to estimate the direct costs associated with the diagnosis and treatment of neurocysticercosis (NCC) during pre-hospitalization, hospitalization, and post-hospitalization periods for 108 NCC patients treated at the Instituto Nacional de Neurologia y Neurocirugia (INNN) in Mexico City, Mexico. Information on clinical manifestations, diagnostic tests, hospitalizations, surgical procedures, prescription medication, and other treatments was collected via medical chart reviews. Uncertain values for costs and frequency of treatments were imputed using bootstrap techniques...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Eloiza Lopes de Lira Tanabe, Ithallo Sathio Bessoni Tanabe, Elane Conceição Dos Santos, Juliana Paula da Silva Marques, Alessandra Abel Borges, Magliones Carneiro de Lima, Letícia Anderson, Ênio José Bassi
Chikungunya virus (CHIKV) causes a self-limiting disease characterized by the onset of fever, skin rash and persistent arthralgia. In the last decade, it has emerged as a serious public health problem causing several outbreaks around the world. Here, we report the CHIKV genotype characterization during the 2016 CHIKV outbreak in Alagoas State, Brazil. Partial E1 sequence from CHIKV-positive samples coming from different cities of Alagoas were submitted to DNA sequencing followed by phylogenetic analysis thus characterizing the virus genotype...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Marilia Ladeira de Araújo, Wellington Duarte, Augusto César Penalva de Oliveira, Maria Rita Polo Gascón, Luiz Augusto Marcondes Fonseca, Raquel de Melo Alves Paiva, Bárbara Santana, Rodrigo Tocantins Calado, Jorge Casseb
OBJECTIVE: We evaluated the association between cognitive deficits and leukocyte telomere length (LTL) in HIV-1-infected individuals. DESIGN: 73 HIV-1-infected patients undergoing neuropsychological evaluation and 91 healthy controls were included in this study. Fifteen HIV-1 positive patients did not have cognitive disorders whereas 26 had asymptomatic neurocognitive disorder (ANI), 13 presented mild to moderate neurocognitive disorder (MND), and 10 had HIV-associated dementia (HAD)...
2018: Revista do Instituto de Medicina Tropical de São Paulo
Kelem Cristina Pereira Mota, Daliane Faria Grama, Natália M Nasser Fava, Letícia Pereira Úngari, Elaine Silva Marques Faria, Márcia Cristina Cury
Among the geohelminths, parasites from the Ascarididae family have a significant role in the human and animal health. This research aims to determine the prevalence of Ascarididae species in the soil in different areas located in a city of Minas Gerais State, Brazil (South America). The study was developed in squares, parks, sports clubs, orchards and municipal children's schools. Samples of sand/soil/grass were collected from January to August 2014. The optical microscope screening was performed through formal-ether and spontaneous sedimentation techniques...
2018: Revista do Instituto de Medicina Tropical de São Paulo
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