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Revista da Sociedade Brasileira de Medicina Tropical

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https://www.readbyqxmd.com/read/29972582/professor-ruth-sonntag-nussenzweig-1928-2018-first-steps-towards-a-successful-anti-sporozoite-vaccine-against-malaria
#1
Antoniana Ursine Krettli
No abstract text is available yet for this article.
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972581/neurosyphilis-manifesting-as-trigeminal-nerve-dysfunction
#2
Leonardo Junio da Silva Medeiros, Edson Marchiori, Paulo Roberto Valle Bahia
No abstract text is available yet for this article.
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972580/encephalitis-and-transverse-myelitis-in-dengue-and-chikungunya-coinfection
#3
Luis Arthur Brasil Gadelha Farias, Juliana Mandato Ferragut, Roberto da Justa Pires Neto
No abstract text is available yet for this article.
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972579/a-rare-case-of-gastric-mucormycosis-in-an-immunocompetent-patient
#4
Bruno Fernandes Barros Brehme de Abreu, Márcio Luís Duarte, Lucas Ribeiro Dos Santos, Angelo Sementilli, Felipe Nunes Figueiras
We report the case of a 23-year-old immunocompetent patient who presented at the emergency department of a Brazilian hospital with epigastric pain and fever. After an investigation that included a computed tomography scan and upper gastrointestinal endoscopy with biopsy, a diagnosis of mucormycosis was established. The patient exhibited favorable progress after surgery and antifungal therapy. Mucormycosis is a rare condition that usually affects immunocompromised patients, with a high mortality rate of up to 85%...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972578/atrial-fibrillation-in-acute-chagas-disease-acquired-via-oral-transmission-a-case-report
#5
Paulo Fernando Pimenta de Souza, Rosane Cheble Domingues Pine, Francisco Lúzio de Paula Ramos, Ana Yecê das Neves Pinto
Atrial fibrillation (AF), a type of supraventricular arrhythmia increases the risk of thromboembolism. Chagas disease has been reported in the Brazilian Amazon region over approximately 20 years. Cardiac abnormalities are recorded in at least 50% of patients and among these, 3.3% develop AF. We describe a case of a 41-year-old man from Muaná, Pará State, who reported a 30-day history of a febrile illness. Acute Chagas disease was confirmed, and an electrocardiogram revealed AF. He was treated with antiparasitic and anti-arrhythmic drugs, beta blockers, and anticoagulants...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972577/combination-therapy-with-liposomal-amphotericin-b-ambisome-n-methylglucamine-antimoniate-glucantime-and-pentamidine-isethionate-in-a-refractory-visceral-leishmaniasis-case
#6
Maria Antonia Ferreira Gomes, Lana Lira Cantidio de Medeiros, Fernanda Paula Dantas Lobo, Nathália Rayane Silva Wanderley, Ana Paula Rodrigues Matos, Tácito do Nascimento Jácome, Maria Goretti Lins Monteiro, Kleber Giovanni Luz
Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis after being treated with liposomal amphotericin B in two distinct occasions. Considering the persistent clinical features and weak response to conventional treatment, a combination therapy with liposomal amphotericin B (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate was initiated, and response to treatment was good...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972576/encephalitis-associated-with-zika-virus-infection-and-reactivation-of-the-varicella-zoster-virus-in-a-brazilian-child
#7
Marcelo Adriano da Cunha E Silva Vieira, Alzira Almeida de Sousa Castro, Daniele Freitas Henriques, Eliana Vieira Pinto da Silva, Fernando Neto Tavares, Lívia Carício Martins, Lucas Melo Guimarães, Talita Antonia Furtado Monteiro, Raimunda do Socorro da Silva Azevedo, Ana Cecíclia Ribeiro Cruz, Pedro Fernando da Costa Vasconcelos
We report a case of encephalitis associated with Zika virus infection and reactivation of varicella-zoster virus in the central nervous system of a Brazilian child. This case raises the possibility that reactivation of the latent varicella-zoster virus may be a mechanism of neurological impairment induced by acquired Zika virus infection.
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972575/can-aspergillus-fumigatus-conidia-cause-false-positive-results-in-the-galactomannan-enzyme-immunoassay-test
#8
Ângela Leitzke Cabana, Josiara Furtado Mendes, Gabriel Baracy Klafke, Tchana Martinez Brandolt, Aryse Martins Melo, Mário Carlos Araújo Meireles, Melissa Orzechowski Xavier
INTRODUCTION: Several factors can cause false-positive results in the galactomannan (GM) test; however, others remain unknown. Presently, the impact of airborne contamination by Aspergillus conidia during enzyme-linked immunosorbent assay (ELISA) remains uninvestigated. METHODS: We studied 12 A. fumigatus isolates. Fungal conidia were serially diluted and tested for GM detection using the Platelia® Aspergillus enzyme immunoassay (EIA). RESULTS: The conidia concentration required for an EIA-positive result was 4...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972574/antiplasmodial-and-antileishmanial-activities-of-compounds-from-piper-tuberculatum-jacq-fruits
#9
Flávio Augusto de Souza Oliveira, Guilherme Matos Passarini, Daniel Sol Sol de Medeiros, Ana Paula de Azevedo Santos, Saara Neri Fialho, Aurileya de Jesus Gouveia, Marcinete Latorre, Elci Marlei Freitag, Patrícia Soares de Maria de Medeiros, Carolina Bioni Garcia Teles, Valdir Alves Facundo
INTRODUCTION: This study assessed the activity of compounds from Piper tuberculatum against Plasmodium falciparum and Leishmania guyanensis. METHODS: The effects of compounds from P. tuberculatum fruits on P. falciparum and L. guyanensis promastigote growth in vitro were determined. Hemolytic action and cytotoxicity in HepG2 and J774 cells were measured. RESULTS: Three compounds showed strong antiplasmodial activity and one compound showed strong antileishmanial activity...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972573/molecular-diagnosis-of-cutaneous-leishmaniasis-in-an-endemic-area-of-acre-state-in-the-amazonian-region-of-brazil
#10
Thais de Araujo-Pereira, Daniela de Pita-Pereira, Regina Barbosa Moreira, Tainah Silva-Galdino, Márcia P de Oliveira Duarte, Reginaldo Peçanha Brazil, Constança Britto
INTRODUCTION: This study proposes to identify the Leishmania species found in the skin lesions of cutaneous leishmaniasis (CL) patients from Brasiléia municipality (Acre). METHODS: Skin biopsy imprints or biopsy fragments were assayed via kDNA-PCR/RFLP and FRET-real-time PCR. RESULTS: Of individuals with suspected CL, 18 were positive for Leishmania kDNA. Leishmania (Viannia) braziliensis (61.1%) and Leishmania (Viannia) guyanensis (5.5%) were identified in the positive samples...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972572/socio-epidemiological-characterization-of-human-leptospirosis-in-the-federal-district-brazil-2011-2015
#11
Ivanildo de Oliveira Correia Santos, Marina Frota de Albuquerque Landi, Eduardo Maurício Mendes de Lima, Laurício Monteiro Cruz, Maria Isabel Rao Bofill, Divino Eterno Dos Santos, Márcio Botelho de Castro
INTRODUCTION: Human leptospirosis (HL) in the Federal District (DF), Brazil, is endemic and requires studies to characterize the socio-epidemiological profile of the vulnerable population. METHODS: Seventy-nine autochthonous cases of HL between 2011-2015 were analyzed based on the databases of the Epidemiological and Environmental Health Surveillance Department, DF. RESULTS: The male population aged 31-45 years represented 86% of the leptospirosis cases; most belonged to the social classes D and E...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972571/detection-of-antibodies-against-leptospira-spp-in-free-living-marsupials-caught-in-the-eastern-amazon
#12
Gleiciane Schupp de Sena Mesquita, Katarine de Souza Rocha, Thamillys Rayssa Marques Monteiro, Marcely Karen Santos do Rosário, Ianny Watuzy Monteiro Baia, Helyanne de Sousa Pereira, Valiria Duarte Cerqueira, Carla Cristina Guimarães de Moraes
INTRODUCTION: Serological surveys are important to assess the health status of wild animals. In this study, antibodies against Leptospira spp, causal agents of leptospirosis, were detected in free-living marsupials in the State of Pará, Brazil. METHODS: Nineteen blood samples collected from marsupials in the municipalities of Peixe-Boi, Viseu, and Castanhal were subjected to microscopic agglutination tests. RESULTS: In total, 36.8% (7/19) of samples were positive, and two exhibited co-agglutination...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972570/serological-and-molecular-detection-of-leptospira-spp-in-dogs
#13
Giulia Soares Latosinski, Felipe Fornazari, Selene Daniela Babboni, Karen Caffaro, Antonio Carlos Paes, Helio Langoni
INTRODUCTION: This study aimed to detect anti-Leptospira spp antibodies and Leptospira DNA in domestic dogs. METHODS: Blood and urine from 106 dogs were evaluated by microscopic agglutination test (MAT) and polymerase chain reaction (PCR), respectively. RESULTS: Six (5.7%) and one (1%) animals were positive by MAT and PCR, respectively. CONCLUSIONS: These results show a low prevalence of infection by Leptospira spp. The absence of positive results for the Icterohaemorrhagiae serogroup indicates the small relevance of these dogs as sources of human leptospirosis...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972569/coexistence-of-virulence-genes-in-methicillin-resistant-staphylococcus-aureus-clinical-isolates
#14
Adriana Medianeira Rossato, Keli Cristine Reiter, Pedro Alves d'Azevedo
INTRODUCTION: The pathogenic versatility of Staphylococcus aureus is attributed to various virulence genes, including enterotoxins and hemolysins. METHODS: Here, the virulence genes in 177 nosocomial MRSA strains in Porto Alegre, Brazil were detected by PCR. RESULTS: The overall prevalence rates were as follows: sea, 4.5%; pvl, 18.6%; tst, 27.7%; hla, 87.6%; and hld, 90.4%. No strain contained all tested genes. However, there was frequent coexistence of tst with pvl and hla with hld (40...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972568/depression-and-anxiety-disorders-among-patients-with-human-t-cell-lymphotropic-virus-type-1-a-cross-sectional-study-with-a-comparison-group
#15
COMPARATIVE STUDY
Pedro Augusto Sampaio Rocha-Filho, Liliana Raulino Goncalves
INTRODUCTION: Studies have linked human T-cell lymphotropic virus type-1 (HTLV-1) to psychiatric disease. METHODS: Patients with HTLV-1 were compared to patients seen by family doctors using a semi-structured questionnaire and the Hospital Anxiety and Depression Scale. RESULTS: Participants with (n=58) and without (n=340) HTLV were compared. Anxiety and depression were associated with greater age, being a woman, spastic paraparesis (depression: PR=4...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972567/clinical-and-laboratorial-features-of-oral-candidiasis-in-hiv-positive-patients
#16
Regiane Nogueira Spalanzani, Karine Mattos, Luiza Inahe Marques, Pedro Fernando Diniz Barros, Pamela Iruama Peres Pereira, Anamaria Mello Miranda Paniago, Rinaldo Poncio Mendes, Marilene Rodrigues Chang
INTRODUCTION: We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972566/neurologic-manifestations-in-emerging-arboviral-diseases-in-rio-de-janeiro-city-brazil-2015-2016
#17
Marina Baptista de Azevedo, Márcia Sandre Coelho Coutinho, Mônica Agostinho da Silva, Denise Bastos Arduini, Juliana Dias Vieira Lima, Rosangela Monteiro, Bárbara Nicácio Bahia Mendes, Maria Cristina Ferreira Lemos, Claudio Pompeiano Noronha, Valéria Saraceni
INTRODUCTION: Dengue has affected Rio de Janeiro City since the 1980s. The sequential Zika and chikungunya virus introductions during 2015 aggravated the health scenario, with 97,241 cases of arboviral diseases reported in 2015-2016, some with neurological disorders. METHODS: Arbovirus-related neurologic cases were descriptively analyzed, including neurological syndromes and laboratory results. RESULTS: In total, 112 cases with non-congenital neurologic manifestations (Guillain-Barré syndrome, 64...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972565/epidemiological-study-of-snakebite-cases-in-brazilian-western-amazonia
#18
Katia Regina Pena Schesquini Roriz, Kayena Delaix Zaqueo, Sulamita Silva Setubal, Tony Hiroshi Katsuragawa, Renato Roriz da Silva, Carla Freire Celedônio Fernandes, Luiz Augusto Paiva Cardoso, Moreno Magalhães de Souza Rodrigues, Andreimar Martins Soares, Rodrigo Guerino Stábeli, Juliana Pavan Zuliani
INTRODUCTION: Brazil has the largest number of snakebite cases in South America, of which the large majority is concentrated in the Midwest and North. METHODS: In this descriptive observational study, we assessed the epidemiological and clinical snakebite cases referred to the Centro de Medicina Tropical de Rondônia from September 2008 to September 2010. RESULTS: We followed up 92 cases from admission until discharge, namely 81 (88%) men and 11 (12%) women, with a mean age of 37 years, and mainly from rural areas (91...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972564/performance-of-the-is6110-taqman%C3%A2-assay-in-the-diagnosis-of-extrapulmonary-tuberculosis-from-different-biological-samples
#19
Fabiana Cristina Fulco Santos, Laís Ariane de Siqueira Lira, Rosana de Albuquerque Montenegro, Juliana Figueirêdo da Costa Lima, Andrea Santos Lima, Haiana Charifker Schindler, Lílian Maria Lapa Montenegro
INTRODUCTION: This study evaluated the performance of the IS6110-TaqMan® assay in different types of biological samples and tissues for laboratory diagnosis of extrapulmonary tuberculosis. METHODS: 143 biological samples and tissues from patients with suspected extrapulmonary tuberculosis from the health services of Recife/Pernambuco/Brazil were evaluated with the IS6110-TaqMan® assay. RESULTS: The sensitivities of the IS6110-TaqMan® assay calculated for blood, urine, both blood and urine samples, tissue biopsies, extrapulmonary body fluid samples, and all samples from patients calculated together were 55...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29972563/a-diagnosis-of-pulmonary-tuberculosis-and-drug-resistance-among-inmates-in-mato-grosso-do-sul-brazil
#20
Eunice Atsuko Totumi Cunha, Marli Marques, Maria do Socorro Nantua Evangelista, Maurício Antonio Pompilio, Renata Terumi Shiguematsu Yassuda, Albert Schiaveto de Souza
INTRODUCTION: High endemic levels of pulmonary tuberculosis in prisons result from overcrowding, limited access to healthcare, delayed diagnosis, sustained transmission owing to poor control measures, and multidrug resistance. This study evaluated locally implemented measures for early pulmonary tuberculosis diagnosis and evaluated resistance to anti-tuberculosis drugs. METHODS: This transversal study employed data from the Mato Grosso do Sul State Tuberculosis Control Program obtained from 35 correctional facilities in 16 counties for 2 periods (2007-2010 and 2011-2014)...
May 2018: Revista da Sociedade Brasileira de Medicina Tropical
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