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Journal of the Indian Medical Association

P R Shanthala, Prema Saldhana, Krishnaraj Upadhyaya
Gynandroblastoma is a rare ovarian mixed sex cord stromal tumour with very few cases reported in literature. These tumours are considered to be potentially malignant. Here a case of gynandroblastoma occurring in a 30-year female is reported who gave history of irregular menstrual bleeding and pain abdomen, there were no signs of virilisation. Computed tomography scan showed a left adnexal mixed density pelvic mass suggesting malignant ovarian tumour. Histological study revealed, the tumour was composed of mixed sex cord elements with predominantly intermediate differentiated Sertoli-Leydig cell component and a second adult type granulosa cell component...
February 2014: Journal of the Indian Medical Association
(no author information available yet)
No effective medical treatment is available for the treatment of ochronotic arthritis which is a manifestation of long standing alkaptonuria. A patient of long standing alkaptonuria progressing to debilitating ochronotic arthritis of both hip and knee jointswith severe deformities has been described. He was successfully treated with bilateral total hip and knee arthroplasty with an excellent four-year follow-up. The occurrence of severe osteoporosis in this condition and the importance of advocating surgery before development of severe deformities of the joints to improve the outcome of surgery has been highlighted in this article...
February 2014: Journal of the Indian Medical Association
Prachis Ashdhir, Shyam Sunder Sharma, Garima Sharma
A 40-year-old man, resident of a rural area of Rajasthan state of India presented with recurrent biliary colic and fever since last 2 years. Examination was normal and investigations revealed a dilated common bile duct with elevated alkaline phosphatase. Magnetic resonance cholangiopancreatography revealed a dilated biliary system without any evident cause. Patient was subjected to endoscopic retrograde cholangioancreatography and it demonstrated biliary dilatation with a linear filling defect in lower common bile duct, further sphinicterotomy was done and a live Fasciola hepatica was extracted using a biliary basket...
February 2014: Journal of the Indian Medical Association
Sumita Mehta, Shalini Rajaram, Sruithi Bhaskaran, Neerja Goel
Proximal femoral focal deficiency (PFFD) is a rare anomaly with an estimated incidence of < 0.2/ 10,000 births. The aetiology of PFFD is unknown though various agents have been implicated including anoxia, ischaemia, mechanical or thermal injury. Herein is reported a case of a 22-year-old primigravida who delivered a baby with PFFD. This patient had developed high grade fever and had undergone ischiorectal abscess drainage at 7 weeks of gestation; maternal hyperthermia combined with anoxic injury might have been contributory factors in the causation of this disorder...
February 2014: Journal of the Indian Medical Association
Biren Prasad Padhy
Hydatid disease is a common parasitic disease of liver. Rupture of aliver hydatid into the peritoneal cavity, either spontaneous or iatrogenic (during surgery) leads to widespread dissemination and is a difficult problem to manage. Surgical management along with long term antihelminthic treatment offers the only hope for such cases. A case of disseminated intra-abdominal hydatid disease and its management has been reported.
February 2014: Journal of the Indian Medical Association
P S Singh, S R S Kushwaha
Eosinophilic ascitis is probably the most unusual and rare presentation of eosinophilic gastroenteritis and is generally associated with the serosal form of eosinophilic gastroenteritis. It is characterised by eosinophilic infiltration of any or all layers of the gut wall and may involve any segment of the gastro-intestinal tract. Peripheral eosinophilia may or may not be present. A case of eosinophilic ascitis that developed eight weeks postpartum in a 30-year-old young female has been reported. She presented with gastro-intestinal symptoms, ascitis and right sided pleurar effusion...
February 2014: Journal of the Indian Medical Association
Kiran Kumar Singal, Neerja Singal, Ram Gopal Sharma, Parveen Gupta
Air travel has become so common these days that about one billion people travel in one year. A few number of the persons travelling by air have suffered or are suffering from one or more medical conditions which may increase risk to passenger himself. There may be additional risk to copassengers, crew of aircraft or safety of aircraft may be compromised. The present article evaluates different medical conditions from pregnancy to cardiovascular diseases in relation to the air travel.
February 2014: Journal of the Indian Medical Association
Nikhil S Patel, Vipin K Sisodia, Samir H Vadher
Current literature has suggested that sentinel lymph node biopsy may replace axillary dissection as the nodal staging procedure of choice in early breast cancer. The aim of this study is to evaluate the effectiveness and accuracy of sentinel lymph node biopsy using methylene blue dye in predicting axillary nodal status in early breast cancer with clinically impalpable axillary lymph nodes. In the period between June 2005 and May 2009, 50 patients with early breast cancer and clinically impalpable axillary lymph nodes, underwent sentinel lymph node biopsy using methylene blue dye followed by completion of axillary dissection in the same setting after taking a written consent from the patients...
February 2014: Journal of the Indian Medical Association
Subrata Dutta, Md Nazarul Islam, Soumen Chakroborty, Anup Mondal, Rakhi Bandopadhay, Sharmistha Gayen, Alok Ranjan
To study the effects of anti-oxidant on tear film parameters in patients with diabetes mellitus, a total of 100 patients of diabetes mellitus with defective Schirmer test and tear film break-up time were enrolled in this study and they were given vitamin C (1000 mg/day) and vitamin E (400 IU/day) for 30 days. Schirmer test and tear break-up, time were re-examined after 1 month. There was significant improvement in values for Schirmer test (p < 0.001) and tear break-up time. Oxidative stress has an influence on how diabetes mellitus affects various systems of body...
February 2014: Journal of the Indian Medical Association
Poonam Dalal, Jagjit Singh
Headache is a common symptom in paediatric hospital practice, the causes may be primary or secondary. A study was conducted in department of paediatrics from May 2005 to February 2007 in order to find out common causes for recurrent headache in children. A total of hundred children in age range of 3-14 years were included in the study. Children with secondary headache were excluded from the study. Various clinical characteristics were studied and based on these, types of headache were categorised using International Headache Society criteria...
February 2014: Journal of the Indian Medical Association
Pankaj K Yadav, Bhavin Shah, Amol Shende, S Rajesh
The objective of this study was to evaluate the role of biceps tendon sheath effusion detected on ultrasound as a diagnostic clue to rotator cuff pathology. Despite being the most common cause of shoulder pain in adults early sonographic changes of rotator cuff tendinopathy are easy to miss. A total of 31 patients out of whom 27 had unilateral shoulder pain and 4 had bilateral complaints under- went ultrasonographic examination of shoulder joint using high frequency linear array transducer. Any fluid surrounding the long head of biceps tendon was noted followed by a careful search for any associated sonographic abnormality involving the rotator cuff...
February 2014: Journal of the Indian Medical Association
Kanai Lal Barik, Uttam Kumar Paul, Anup Kumar Bhattacharyya, Amit Adhikary, Gajanand Agarwal, Kriti Sundar Rana
Epilepsy is a common paediatric neurologic disorder that is difficult to manage in a substantial portion of children, highlighting the continued need for more effective and better tolerated drugs. A multicentric study was conducted from August, 2011 to July, 2013 using levetiracetam (LEV) in newely diagnosed epilepsy in 122 young children of 1-5 years age group to find its role in practical scenario depending upon the knowledge from prior literature available. It has been demonstrated effective as adjunctive therapy as well as monotherapy for new-onset partial seizures and generalised tonic-clonic seizures (GTCS) but it acts better as adjunctive therapy than the monotherapy...
February 2014: Journal of the Indian Medical Association
Garima Kapoor, Sudha Salhan, Nivedita Sarda, Deepika Aggarwal
The aim of this study is to compare the effectiveness of 100 mg versus 200 mg mifepristone along with misoprostol for medical abortion in gestation upto 56 days. This is a prospective controlled study. Eighty women seeking medical abortion with a gestation up to 56 days were included in the study. The women were randomly allotted into two groups. They received 100 mg/200 mg mifepristone on day 1 followed by 800 mcg misoprostol two days later. Women who had not aborted completely by day 14, received a repeat dose of 400 mcg misoprostol and were evaluated on day 21 for completeness of the procedure...
February 2014: Journal of the Indian Medical Association
Kalishankar Bhattacharyya, Nikhilesh Mandal, Uttam Kumar Paul, Anup Kumar Bhattacharyya, Keshab Sinharay, Kripasindhu Gantait
Post-traumatic seizure (PTS) is the development of recurrent seizures following head trauma and has a high clinical relevance. We tried to understand the epidemiology of PTS in a multicentric pro- spective study during the period May 2010 to April 2012. We included 320 patients excluding poor Glasgow coma scale (GCS) ie, <4 and history of previous epilepsy. At a median follow-up of one year, 49 patients (15.31%) developed PTS. Incidence of immediate, early and late onset seizures were 27 (8.4%), 14 (4.4%), 9 (2...
February 2014: Journal of the Indian Medical Association
Subramanian Natarajan, Poonam Rudrawar
Bronchiectasis is an abnormal permanent dilatation distortion and destruction of the airways with both pulmonary and extrapulmonary side-effects. The aim of the study was to find out the presenting features, aetiologies and socioeconomic factors in patients of bronchiectasis. It is a prospective observational study comprising 53 patients over aperiod of two years. Aetiologies were determined using Kuppuswamy's socioeconomic scale. Number of exacerbations and mortality were noted. The age ranged from 14 to 80 years (mean: 43...
February 2014: Journal of the Indian Medical Association
Neerja, Kuldeep Jain
The study aims to analyse the role of hysteroscopy-laparoscopy in diagnosis and treatment of infertility with effect on pregnancy outcome. The study group comprised 200 patients of 20-30 years age (125 with primary and 75 with secondary infertility). Hysterosalpingography (HSG) was done in all. Diagnostic as well as operative hysteroscopy-laparoscopy if required were performed in the same sitting in cases who have already been treated for 6 months and did not conceive, with unexplained cause or with abnormal HSG findings...
February 2014: Journal of the Indian Medical Association
(no author information available yet)
The study was aimed for molecular detection of mycobacterial DNA in different clinical samples using real-time polymerase chain reaction (RT-PCR) system and rapid diagnosis of tuberculosis. A total of 508 clinical specimens (blood 343, menstrual fluid 53, endometrial tissue 43, body fluid 36, pus from lymph nodes 18, sputum 8, urine 5 and semen 2) were included in this study. We extracted DNA using QIAamp DNA Mini Kit (QIAGEN, Germany) and performed real-time assay using Rotor-Gene Q machine from Corbett Research, Australia for specific amplification of IS6110 sequence of mycobacterial genome...
February 2014: Journal of the Indian Medical Association
T G Krishna Murthy
No abstract text is available yet for this article.
February 2014: Journal of the Indian Medical Association
Somedeb Gupta, Debabrata Das
Conjunctival melanoma is a rare ocular malignancy occurring most frequently in aged patients. It is a potentially life-threatening condition. This article presents history and management of a case of malignant melanoma of conjunctiva resembling a horn.
January 2014: Journal of the Indian Medical Association
Chhaya Roy, Asit Ranjan Deb, Madhumay Pal, Diptimoy Das, Ananya Mandal, Sima Mukhopadhyay
Small cell carcinoma of the urinary bladder is extremely rare. In this report, a case of non-metastatic small cell carcinoma of the urinary bladder treated by systemic chemotherapy followed by adjuvant external radiotherapy, with a brief review of the epidemiology, clinical features, diagnosis, pathological features, staging, treatment and prognosis about this neoplasm is reported. A 53 years old man attended with sign and symptoms suggestive of a bladder cancer. Computed tomography of the whole abdomen showed a large tumour at right lateral wall of the bladder...
January 2014: Journal of the Indian Medical Association
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