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Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections

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https://www.readbyqxmd.com/read/27822761/erratum-to-new-data-on-avifauna-of-the-ustyurt-plateau-in-the-holocene
#1
A E Nekrasov, P A Kosintsev, Z Samashev, A Ongar, T V Loshakova, V N Bolshakov
No abstract text is available yet for this article.
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822760/cyanobacteria-in-iron-banded-formations-of-the-kursk-magnetic-anomaly
#2
A Yu Rozanov, M M Astafieva, L V Zaitseva, N A Alfimova, S B Felitsyn
Fossilized cyanobacteria(?) represented by trichomes enclosed in common sheaths were detected in early Proterozoic iron banded formations of the Kursk magnetic anomaly (limonite-martite ores of the Lebedinsky mine and iron banded formations of the Korobkovskoye deposit). These fossils morphologically similar to current representatives of the genus Microcoleus were buried in situ.
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822759/cytokine-pattern-of-the-breast-tumor-supernatant
#3
A I Autenshlyus, T A Kunts, K V Karpukhina, E S Mikhaylova, N A Varaksin, I O Marinkin, V V Lyakhovich
Cytokine production was evaluated in supernatants of cultured tumor cells that were obtained by biopsy of the breast invasive ductal carcinoma (IDC) and breast fibroadenoma (FA) and grown in vitro. In the IDC supernatants, the concentrations of pro-inflammatory (pro-oncogenic) cytokines IL-17, IL-18, and IFNγ and of IL-1 receptor antagonist were significantly higher than in the FA cell supernatants. The concentrations of anti-inflammatory cytokine IL-10 and MCP-1 protein in supernatants of IDC cells were significantly lower than those determined in FA supernatants...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822758/effect-of-polypeptides-from-sea-anemone-heteractis-crispa-on-the-rodent-blood-pressure-heart-rate-and-hemostasis
#4
L A Skobtsova, I A Dyachenko, Ya A Andreev, Yu A Logashina, A N Murashev, E V Grishin
АРНС1-3 peptides, modulators of TRPV1 receptors, have been administered to SD rats to study their influence on the animal hemostatic system, heart rate, and blood pressure. None of АЗРС1-3 polypeptides have any effect on the hemostatic system. Both АРНС1 and АРНС2 polypeptides increased significantly the heart rate, but they did not affect blood pressure, which was probably caused by an ability of these polypeptides to modify animal thermoregulation.
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822757/involvement-of-dihydropyridine-sensitive-calcium-channels-in-high-asynchrony-of-transmitter-release-in-neuromuscular-synapses-of-newborn-rats
#5
V F Khuzakhmetova, L F Nurullin, E A Bukharaeva, E E Nikolsky
Experiments on neuromuscular synapses of rats at different stages of ontogenesis have been performed. It has been found that one of the reasons of higher asynchrony of the release of single quanta of acetylcholine in the synapses of newborn animals is the activity of the presynaptic dihydropyridine-sensitive calcium channels of the L-type.
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822756/the-time-scale-of-adaptation-in-tonal-sequence-processing-by-the-mouse-auditory-midbrain-neurons
#6
E S Malinina, M A Egorova, G D Khorunzhii, A G Akimov
The time course of poststimulatory adaptation of the inferior colliculus central nucleus (ICC) of CBB6F1 hybrid mice to sound sequences, specifically, series of four tonal stimuli presented at intervals of 0, 2, 4, 10, 20, 50, 100, 200, 500, 700, 1000, and 1500 ms were studied. Assessment of the adaptation of the entire neuronal population have shown that, at an interstimulus interval of 0-200 ms, the response to the first tone in a series is significantly stronger than those to the second to fourth tones, the strengths of the latter three responses not differing significantly from one another...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822755/myosin-accelerates-synaptic-vesicle-recycling-in-the-motor-nerve-endings
#7
P N Grigoryev, A L Zefirov
Neurotransmitter release and exocytosis of synaptic vesicles in the motor nerve endings of the frog cutaneous-pectoris muscle were studied using electrophysiological and optical methods under the conditions of inhibition of the myosin light-chain kinase and non-muscle myosin by the specific inhibitors ML-7 (12 μM) and (-)-blebbistatin (100 μM). At high-frequency stimulation (20 pulses/s), these inhibitors strengthened suppression of transmitter release during the first 20-25 s and slowed down the release of the fluorescent dye FM 1-43...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822754/roles-of-leptin-and-ghrelin-in-the-regulation-of-the-phenotype-and-cytokine-production-by-nk-cells-from-peripheral-blood
#8
S V Shirshev, I V Nekrasova, E G Orlova, O L Gorbunova
Both leptin and ghrelin used separately at the concentrations corresponding to trimesters II-III of pregnancy increase the number of CD56(bright) NK cells in mononuclear cell suspension; their combination also enhances the L-selectin expression on the surface of these cells in the culture. These hormones do not affect the production of TGF-β1, IL-17А, or IFN-γ by NK cells, and they inhibit the production of IL-10. Leptin decreses the IL-4 production by NKp46(+) cells, but the presence of ghrelin abrogates this effect...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822753/specific-features-of-adaptation-of-rats-to-chronic-cold-treatment
#9
S Yu Tsibul'nikov, L N Maslov, N V Naryzhnaya, V V Ivanov, Yu B Lishmanov
Permanent exposure of rats to four-week cold treatment at +4ºC for 24 h/day resulted in increased weights of the brown adipose tissue, adrenals, and spleen and had no effect on the levels of cortisol and corticosterone in the blood serum. Similar data were observed after exposure of rats to intermittent four-week cold treatment at +4ºC for 8 h/day. After short-term exposure of rats to intermittent cold treatment at +4ºC for 1.5 h/day, all indices studied were similar to those observed in intact animals.
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822752/investigation-of-the-effects-of-gaba-receptor-agonists-in-the-differentiation-of-human-induced-pluripotent-stem-cells-into-dopaminergic-neurons
#10
S A Antonov, E V Novosadova, E L Arsenyeva, M A Grefenstein, A A Zykova, A G Kobylyansky, E S Manuilova, I A Grivennikov, S N Illarioshkin, N F Myasoedov
The influence of GABA receptor agonists on the terminal differentiation in vitro of dopaminergic (DA) neurons derived from IPS cells was investigated. GABA-A agonist muscimol induced transient elevation of intracellular Ca(2+) level ([Ca(2+)] i ) in the investigated cells at days 5 to 21 of differentiation. Differentiation of cells in the presence of muscimol reduced tyrosine hydroxylase expression. Thus, the presence of active GABA-A receptors, associated with phenotype determination via Ca(2+)-signalling was demonstrated in differentiating human DA neurons...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822751/memantine-attenuates-cognitive-impairments-after-status-epilepticus-induced-in-a-lithium-pilocarpine-model
#11
S V Kalemenev, O E Zubareva, V V Sizov, V V Lavrent'eva, N Ya Lukomskaya, K Kh Kim, A V Zaitsev, L G Magazanik
The capability of memantine, a noncompetitive antagonist of the NMDA receptors, to prevent impairments of cognitive functions in rats was investigated in the lithium-pilocarpine model of epilepsy. After status epilepticus, rats exhibited impaired exploratory behavior and spatial memory, and a decline of extinction of orienting behavior. Memantine administration prevented these disturbances. Thus, the blockade of the NMDA receptors immediately after status epilepticus allowed prevention of the development of the possible cognitive impairments...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822750/effects-of-intranasal-administration-of-the-peptide-antagonist-of-type-i-vaniloid-receptor-trpv1-in-the-rodent-central-nervous-system
#12
A O Tishkina, E K Mart'yanova, Yu A Logashina, Ya A Andreev, S F Khaibullina, E V Martynova, A A Rizvanov, N V Gulyaeva, E V Grishin
Intranasal administration of the polypeptide APHC3, an antagonist of the TRPV1 receptor, had acute anxiolytic and antidepressant effects, as well as an ability to modify the microglial response to proinflammatory stress and cytokine profile of the hippocampus. However, the acute antidepressant effect of the polypeptide was not related to the attenuation of neuroiflammation and probably had a different mechanism. The use of intranasal administration of the APHC3 peptide as a therapeutic approach aimed at decreasing depression symptoms needs additional studies in order to find the mechanism of action of this polypeptide in the central nervous system (CNS)...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822749/effect-of-electromagnetic-microwave-radiation-on-the-growth-of-ehrlich-ascites-carcinoma
#13
O V Kryukova, V F Pyankov, A F Kopylov, R G Khlebopros
Daily exposure of mouse recipients of Ehrlich ascites carcinoma to electromagnetic radiation of the microwave range leads to a change in the dynamics of tumor growth by decreasing the total number of cells. The number of tumor cells with blebbing morphological signs after microwave radiation increases gradually with tumor growth. The maximum content of tumor cells in the state of blebbing is observed during active proliferation in tumor-recipient mice of the control group (without irradiation).
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27822748/suppression-of-ehrlich-carcinoma-growth-by-cobra-venom-factor
#14
T I Terpinskaya, V S Ulashchik, A V Osipov, V I Tsetlin, Yu N Utkin
Cobra venom factor (CVF) depletes the complement system of the blood by forming stable convertase C3/C5 of the alternative pathway. We found that CVF from the Thailand cobra venom slows down the growth of subcutaneous Ehrlich carcinoma (EC) in mice at a dose of 1.7 nmol/g. Previously, we described a similar effect for the nerve growth factor (NGF) from the venom of this cobra. However, these factors did not exhibit either synergy or additive effect. On the contrary, they neutralized the antitumor effect of each other when they were administered simultaneously...
September 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27595833/effect-of-pregnancy-specific-%C3%AE-1-glycoprotein-on-indoleamine-2-3-dioxygenase-activity-in-human-monocytes
#15
S A Zamorina, V P Timganova, M S Bochkova, P V Khramtsov, M B Raev
The role of heterogenic human pregnancy-specific glycoprotein (PSG), obtained by the authors' technology, in the regulation of the indoleamine-2,3-dioxygenase (IDO) activity in female blood monocytes has been studied in vitro. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-γ. Upon the induction of cell proliferation by lipopolysaccharides, the stimulating effect was obtained only with 10 μg/mL of PSG. Enhanced IDO activity is probably a factor of peripheral immunological tolerance and antimicrobial protection against intracellular infections in the gestation period...
July 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27595832/effects-of-%C3%AE-endorphin-on-the-production-of-reactive-oxygen-species-il-1%C3%AE-tnf-%C3%AE-and-il-10-by-murine-peritoneal-macrophages-in-vivo
#16
S V Gein, T A Baeva, V O Nebogatikov
It has been demonstrated that β-endorphin stimulates the zymosan-induced secretion of reactive oxygen species and suppresses the spontaneous production of IL-1β and IL-10 by murine peritoneal macrophages in vivo.
July 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27595831/specific-effect-of-the-hldf-differentiation-factor-on-the-cytokine-production-potential-of-immunocompetent-blood-cells-in-stomach-adenocarcinoma
#17
A I Autenshlyus, T A Kunts, E S Mikhaylova, N A Varaksin, A P Bogachuk, V M Lipkin
The cytokine production potential of immunocompetent cells from the blood of stomach adenocarcinoma patients was analyzed after the pretreatment of cells with the HLDF differentiation factor with subsequent exposure to polyclonal activators (HLDF+PA). IL-1β, IL-1Ra, TNFα, IL-2, IL-6, IL-8, IL-10, IL-17, IL-18, IL-18BPa, IFNγ, G-CSF, and GM-CSF were quantified in the supernatants after precipitation of the cells. Specific effects of HLDF+PA were manifested as an increase in the production of IL-8, IL-17, and GM-CSF due to suppression of Th1-dependent immune reactions in a Th17-mediated mechanism that is a part of a broader functional antagonism of Th1 and Th17 lymphocyte subpopulations...
July 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27595830/immune-complexes-that-contain-hiv-antigens-activate-peripheral-blood-t-cells
#18
L B Korolevskaya, K V Shmagel, E V Saidakova, N G Shmagel, V A Chereshnev
Uninfected donor T cells were treated in vitro by model immune complexes that contained either HIV or hepatitis C virus (HCV) antigens. Unlike HCV antigen-containing complexes, the immune complexes that contained HIV antigens have been shown to activate peripheral blood T cells of uninfected donors under in vitro conditions. Both the antiviral antibodies and HIV antigen were involved in the activation process. The unique properties of the immune complexes formed by HIV antigens and antiviral antibodies are believed to result from the virus-specific antibody properties and molecular conformation of the antigen-antibody complex...
July 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27595829/the-first-results-of-using-the-allium-test-in-estimating-the-chemical-and-radiation-toxicity-of-bottom-sediments-in-the-yenisei-river
#19
A Ya Bolsunovsky, E A Trofimova, A V Zueva, D V Dementiev
The first results of the use of the Allium test for estimation of toxicity of bottom sediments in the Yenisei River and the effect of external γ-radiation under laboratory conditions are presented. The effect of stimulation of the onion root growth, i.e., the absence of toxicity was discovered in toxicological experiments using bottom sediments and under external γ-radiation. The stimulating effect of radiation on the growth of onion roots limits the use of the Allium test for testing samples from the Yenisei River ecosystem in the zone subjected to the impact of radioactive discharges from the Mining and Chemical Combine...
July 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/27595828/new-data-on-the-distribution-and-taxonomy-of-fossil-soergel-s-ox-soergelia-sp-bovidae-artiodactyla-mammalia-in-yakutia
#20
G G Boeskorov
Novel findings of fossil remains of the extinct artiodactyl Soergel's ox, as well as some findings that were not analyzed previously, are presented in the article. Soergelia remains are extremely rare; therefore, the species range of these animals remains uncharacterized by now and the taxonomic positions of some findings are not clear. Analysis of the new material extends the knowledge on the species range and the limits of morphological variation of the Soergel's ox and allowed a more precise assessment of the taxonomic position of the findings from Yakutia...
July 2016: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
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