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Bulletin of Tokyo Dental College

Raghavendra S Medikeri, Vinayak Meharwade, Parikshit M Wate, Suresh V Lele
Immediate implant placement can be successful, even at infected sites. The adjunctive effects of concomitant use of platelet-rich fibrin (PRF) and decalcified freeze-dried bone allografts (DFDBA) at periapically infected sites remains to be determined, however. The purpose of this prospective study was to investigate the effect of combined use of PRF and DFDBA on immediate implant survival at tooth extraction sites exhibiting periapical lesions. Implants were immediately placed in 8 patients under a standard chemotherapeutic protocol...
2018: Bulletin of Tokyo Dental College
Toshihito Yoshimoto, Masamitsu Serikawa, Kazunari Higa, Kei Kitamura, Masaaki Kasahara, Masahito Yamamoto, Shinichi Abe
The objective of this study was to investigate the effects of mesenchymal cells on myoblasts in long-term cultivation of myoblast cell sheets. Sheets of myoblasts and mesenchymal cells from Japanese rabbit oral mucosa were generated and analyzed by histochemistry, Western blot, and reverse transcription-polymerase chain reaction. The presence of desmin and type IV collagen, which is seen in normal muscle tissue, was also confirmed in all the sheets produced. Expression of desmin and type IV collagen showed a decrease under co-culture conditions...
2018: Bulletin of Tokyo Dental College
C N Guruprasad, A R Pradeep
Interleukin (IL)-34 has recently been identified as an alternative ligand for colonystimulating factor-1 receptor and plays an important role in osteoclastogenesis. The aim of this study was to assess and compare IL-34 levels in gingival crevicular fluid (GCF) and plasma in obese individuals in the presence or absence of periodontal disease and to determine whether they showed a correlation with disease severity. Forty patients aged between 25 and 40 yr were enrolled and categorized into 4 groups: 10 non-obese patients with healthy periodontium (Group I); 10 obese patients with healthy periodontium (Group II); 10 non-obese patients with chronic periodontitis (Group III); and 10 obese patients with chronic periodontitis (Group IV)...
2018: Bulletin of Tokyo Dental College
Naoki Tamura, Takashi Takaki, Nobuo Takano, Takahiko Shibahara
The purpose of this study was to investigate factors involved in stress on locking mini-plate/screws used in orthognathic surgery based on patient-specific 3-dimensional finite element analysis. Data were obtained from 10 patients undergoing mandibular advancement by bilateral sagittal split ramus osteotomy. All underwent osteosynthesis with 2.0-mm titanium locking mini-plate/screws. A 3-dimensional finite element model of the mandible was created for each patient and each model subjected to the same loading conditions, which produced different stress values on locking mini-plate/screws...
2018: Bulletin of Tokyo Dental College
Akane Takenouchi, Hiroe Arai, Etsuyo Otani, Asami Fushimi, Takashi Matsukubo
The aim of this randomized-controlled, single-blinded study was to compare the effects of mechanical tooth cleaning (MTC) and ultrasonic debridement (UD) on oral hygiene status in healthy young adults. Thirty-seven participants (mean age: 20.3±0.62 years) were divided into 3 groups after pre-examination: group A, receiving MTC; B, receiving MTC+UD using a universal insert (UDUI); and C, receiving MTC+UD using a probe-shaped insert (UDPI). All participants were required to abstain from oral hygiene for 24 hours after the allocated intervention, after which they were examined...
2018: Bulletin of Tokyo Dental College
Yuki Kojima, Mizuha Kojima, Kaori Nohara, Yutaka Sakaguchi
Parkinson's disease (PD) is a highly prevalent, long-term neurodegenerative disorder that is sometimes treated by deep brain stimulation (DBS), which significantly reduces the need for dopaminergic drug therapy and improves quality of life. Such patients are cautioned, however, that dental instruments such as a dental turbine or ultrasonic scaler may adversely affect the functioning of such a system. Here, we report dental treatment for right maxillary tooth pain in a 65-year-old woman undergoing DBS for PD...
2018: Bulletin of Tokyo Dental College
Katsutoshi Kokubun, Kenichi Matsuzaka, Yoshihiko Akashi, Masami Sumi, Kei Nakajima, Satoshi Murakami, Masato Narita, Takahiko Shibahara, Takashi Inoue
Congenital epulis is an unusual benign oral mucosal lesion in newborns with no tendency to recur after excision. The histogenesis of the lesion is unknown, but it is believed to be of mesenchymal origin. We describe a case of congenital epulis (20×10 mm) in the mandibular gingiva of a newborn. The mass, which was smooth-surfaced and pedunculated with a healthy color, was surgically removed at 5 months post-birth. Histologically, the tumor consisted mainly of large eosinophilic granular cells. Immunohistochemical studies revealed intense staining for vimentin, STRO-1, and CD44, suggesting that it was derived from mesenchymal cells...
2018: Bulletin of Tokyo Dental College
Paulo Henrique Braz-Silva, Alan Motta do Canto, Leticia Oliveira, Fabiana Martins, Alessandro Antônio Pereira da Costa, João Adolfo Costa Hanemann
Sclerosing polycystic adenosis (SPA) is a rare benign lesion of the salivary glands which appears histologically similar to sclerosing adenosis and fibrocystic disease of the mammary gland. To date, 67 cases of SPA have been reported in the literature, with the lesion arising in the minor salivary glands in only 9. The present report describes the 10th case of SPA. The patient was a 39-year-old Brazilian man who presented with an asymptomatic nodule on the ventral surface of the tongue. Based on a clinical diagnosis of benign salivary gland neoplasm, an excisional biopsy of the lesion was performed...
2018: Bulletin of Tokyo Dental College
Daichi Kita, Takashi Kinumatsu, Yoshihito Ishii, Kazuya Yamanouchi, Atsushi Saito
Here, we report a case of gingival fenestration requiring periodontal plastic surgery. The patient was a 32-year-old man presenting with the chief complaint of esthetic impairment and gingival twitching due to gingival fenestration. Baseline examination revealed localized periodontal breakdown, including gingival fenestration in the lower right central incisor (#41). Periodontal examination revealed 3% of sites with a probing depth of ≥4 mm and 8.9% with bleeding on probing. Radiographic examination revealed vertical bone loss in #15 and 36, together with buccal fenestration in #41...
2018: Bulletin of Tokyo Dental College
Koichi Yoshino, Koji Ito, Masahiko Kuroda, Naoki Sugihara
Diagnosing vertical root fracture (VRF) is difficult. Here, we retrospectively investigated the duration from initial symptoms to a definite diagnosis of VRF in dental offices. Data were collected on patients with VRF between July 2013 and June 2015. Initial symptoms were ascertained from clinical records. The focus was on the maxillary second premolars and mesial roots of the mandibular first molars, where VRF is most frequent. All VRF in the bilateral dentition was analyzed. Only cases in which the buccal-lingual plane of the root was fractured were included...
2018: Bulletin of Tokyo Dental College
Svitlana Veniaminivna Kolomiiets, Kristina Oleksandrivna Udaltsova, Tetiana Andriivna Khmil, Alina Mykolaiivna Yelinska, Olena Anatoliivna Pisarenko, Viktoriya Ihorivna Shynkevych
Sialolithiasis is one of the most common and extensively obstructive disorders of the major salivary glands. Here, we report 3 cases of sialolithiasis in the submandibular salivary gland showing symptomatic similarities to other dental and non-dental disorders of the maxillofacial area. How the various clinical features of this condition and findings on 3D-CT may lead to a misdiagnosis are also discussed. In the first case, that of a 45-year-old woman, a final diagnosis of a non-radiopaque submandibular sialolith allowed the initially indicated surgical extraction of a malerupted and semi-impacted right mandibular 3rd molar to be abandoned...
2018: Bulletin of Tokyo Dental College
Hodaka Sasaki, Tomoki Hirano, Syuntaro Nomoto, Yasushi Nishii, Yasutomo Yajima
Here, we report a case of dental implant treatment involving computer-assisted surgery for bilateral agenesis of the maxillary lateral incisors. The patient was a 39-year-old woman with the chief complaint of functional and esthetic disturbance due to maxillary and mandibular malocclusion. The treatment plan comprised non-extraction comprehensive orthodontic treatment and prosthodontic treatment for space due to the absence of bilateral maxillary lateral incisors. A preliminary examination revealed that the mesiodistal spaces left by the absent bilateral maxillary lateral incisors were too narrow for implant placement (right, 5...
2018: Bulletin of Tokyo Dental College
Caroline T S Oliveira, Fredson M A de Carvalho, Leonardo C O Gonçalves, Jessyca M N de Souza, Lucas F R Garcia, André A F Marques, Samir N de Souza
The axial displacement of a tooth within the alveolar bone is called traumatic intrusive luxation. The treatment of immature permanent teeth with incomplete root formation is a challenging procedure, as the prognosis is uncertain. The objective of the present article is to report the successful treatment of traumatic intrusive luxation in teeth with incomplete root formation, where mineral trioxide aggregate (MTA) was used as an apical plug to induce apexification. A 10-year-old boy was referred to our department for emergency treatment of dentoalveolar trauma to the maxillary central incisors...
2018: Bulletin of Tokyo Dental College
Taiki Suzuki, Ryo Sekiya, Yuji Hamada, Miho Takahashi, Kazunari Karakida, Haruo Sakamoto
Here, we report a case of fatal bleeding in conjunction with mandibular medicationrelated osteonecrosis of the jaw (MRONJ). A 75-year-old Japanese man was referred to our department with osteonecrosis of the jaw due to bisphosphonate (BP) for multiple bone metastases from prostate cancer. Aggressive surgical intervention was ruled out due to a poor prognosis in terms of life expectancy. Death occurred due to hemorrhagic shock resulting from massive oral bleeding caused by necrosis of the mandible. Numerous reports have suggested that jaw necrosis is induced not only by BP, but also RANKL antibody, steroids, and molecularly-targeted agents...
2018: Bulletin of Tokyo Dental College
Ryuta Kikuchi, Kimiharu Ambe, Hideki Kon, Satoshi Takada, Hiroki Watanabe
Localization of the nitric oxide (NO)-producing enzyme, nitric oxide synthase (NOS), and its functions are currently being investigated in several tissues and organs. It has been suggested that NO is involved in nerve cell death and the development of neurodegenerative disease. The purpose of this study was to immunohistochemically investigate expression of NOS to clarify its function in the degeneration and regeneration of transected mouse sciatic nerve. Scattered neuronal NOS (nNOS)-positive Schwann cells observed on the central side of the stump on day 1 after transection showed an increase in number on day 7...
2018: Bulletin of Tokyo Dental College
Chie Tachiki, Yasushi Nishii, Takashi Takaki, Kenji Sueishi
Surgical orthodontic treatment has been reported to improve oral health-related quality of life (OHRQL). Such treatment comprises three stages: pre-surgical orthodontic treatment; orthognathic surgery; and post-surgical orthodontic treatment. Most studies have focused on change in OHRQL between before and after surgery. However, it is also necessary to evaluate OHRQL at the pre-surgical orthodontic treatment stage, as it may be negatively affected by dental decompensation compared with at pre-treatment. The purpose of this prospective study was to investigate the influence of surgical orthodontic treatment on QOL by assessing change in condition-specific QOL at each stage of treatment in skeletal class III cases...
2018: Bulletin of Tokyo Dental College
Taiki Suzuki, Ichiro Tanaka, Ryuta Osaka, Akira Baba, Kazumichi Sato, Tomohiro Yamauchi, Takeshi Nomura, Nobuo Takano
The purpose of this study was to investigate three-dimensionally temporal change in flap volume after free flap reconstructive surgery in tongue cancer patients. The results revealed an average change in flap volume of 82.3% at 1 year postoperatively. Change in tongue volume at approximately 6 months postoperatively showed a correlation with triglyceride levels. A correlation was also found between albumin levels and tongue volume at 1 year onwards postoperatively. The goal of such surgery in patients with tongue cancer is to reconstruct a functional tongue...
2017: Bulletin of Tokyo Dental College
Kunihiko Nojima, Mayuko Onoda, Yasushi Nishii, Kenji Sueishi
We performed orthodontic treatment, fitted prostheses, and provided restorative treatment in a patient with Bloch-Sulzberger syndrome and cleft lip and palate during the early mixed dentition period. We report the case after a subsequent 6-year retention phase including the period of pubertal growth. A girl aged 8 years 4 months visited our hospital with the chief complaint of crowding of the anterior teeth and anterior crossbite. She had bilateral cleft lip, alveolus, and palate; a Class II molar relationship; winging of both the maxillary bilateral central incisors; and spacing in the mandibular anterior teeth arches...
2017: Bulletin of Tokyo Dental College
Satoru Ogane, Akira Watanabe, Nobuo Takano, Takahiko Shibahara
The eruption of a tooth into the nasal cavity is a rare clinical entity. We report a case of an inverted supernumerary tooth in the nasal cavity. A 2-year-old boy was referred to our institution after examination at a local otorhinolaryngology department for otitis media. Radiological examination revealed a tooth-like structure in the right nasal cavity. The tooth was protruding from the floor of the nasal cavity along with granulation tissue. The diagnosis was an inverted tooth in the right nasal cavity. Forceps extraction was performed under general anesthesia...
2017: Bulletin of Tokyo Dental College
Keiichiro Tsujino, Seikou Shintani
We report the successful morphological correction of a maxillary lateral incisor with a talon cusp and the preservation of vital pulp by employing an intentional partial pulpotomy. A talon cusp is a comparatively rare morphological tooth anomaly that may cause multiple clinical problems. An 11-year-old girl was referred to our department for morphological correction of a maxillary lateral incisor with a talon cusp prior to orthodontic treatment. Following a detailed CT examination of the interior morphology, the abnormal cusp was resected and an intentional partial pulpotomy performed...
2017: Bulletin of Tokyo Dental College
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