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Bulletin of Tokyo Dental College

Kazumichi Sato, Taiki Suzuki, Yusuke Sanjo, Takashi Ushioda, Kazuhiko Hashimoto, Hirokazu Saito, Satoru Ogane, Nobuo Takano, Takeshi Nomura
Disseminated carcinomatosis of the bone marrow (DCBM) is characterized by diffuse metastasis to bone marrow and sudden mortality. To the best of our knowledge, no studies to date have reported progression of oral squamous cell carcinoma to DCBM. Herein, we report a case of squamous cell carcinoma in the maxillary gingiva suspected of progressing to DCBM. A 64-year-old woman presented with white lesions on the left maxillary gingiva. The lesions were diagnosed as squamous cell carcinoma (T2, N0, M0), and partial maxillectomy performed...
October 18, 2018: Bulletin of Tokyo Dental College
Yoshitaka Furuya, Masae Yamamoto, Taichi Ito, Takashi Takaki, Takahiko Shibahara, Yasutomo Yajima
An abnormal maxillomandibular ridge relationship frequently hinders oral implant treatment in patients with jaw deformities. Here, we describe a patient who was experiencing difficulty using dentures due to multiple maxillary tooth loss and mandibular prognathism. Treatment comprising sagittal splitting ramus osteotomy and alveolar ridge augmentation using bone grafts harvested from the mandibular ramus followed by implant treatment yielded good outcomes. The patient was a 47-year-old woman presenting with an unstable upper partial denture...
October 18, 2018: Bulletin of Tokyo Dental College
Eiko Makino, Keiichiro Tsujino, Takenobu Ishii, Seikou Shintani, Kenji Sueishi
The aim of this study was to obtain basic data that might serve as criteria in the diagnosis of delayed eruption of the permanent teeth. The synchronicity of the eruption of corresponding contralateral teeth was determined. Data were obtained on both the deciduous and permanent dentition based on records made every 2 months at the Department of Pediatric Dentistry of Tokyo Dental College. These data were then used to investigate bilateral differences in the timing of eruption of the permanent teeth. Over 80% of incisors, first molars, mandibular canines, and maxillary first premolars erupted within 4 months of their contralateral counterparts, while this occurred in 75% of maxillary canines, mandibular first premolars, and mandibular second molars, 70% of maxillary and mandibular second premolars, and 65% of maxillary second molars...
October 18, 2018: Bulletin of Tokyo Dental College
Midori Ohta, Takayuki Ueda, Kaoru Sakurai
The deterioration in masticatory function often seen in older adults rules out the consumption of hard foods, while a common decline in autonomic nervous response often observed in older adults may result in maladjustment to environmental stresses. The purpose of this study was to investigate whether autonomic nervous activity in older adults increased during the mastication of soft foods compared to at rest. The participants comprised 9 volunteer nursing home residents aged 78 to 100 years. All consumed soft rice as a grain dish and coarsely chopped food as side dishes...
October 18, 2018: Bulletin of Tokyo Dental College
Masayuki Hirota, Kenichirou Suga, Takahiko Shibahara
The purpose of the present study was to investigate the relevance of the external morphology of the mandibular ramus, internal bone tissue structure, and maxillofacial morphology at the site for sagittal split ramus osteotomy among different facial skeletal patterns. A total of 80 patients with jaw deformities who underwent sagittal split ramus osteotomy were included in the study. The patients were divided into two groups based on facial skeletal type (skeletal Class II or skeletal Class III). A further 7 patients with no skeletal abnormalities were established as the control group (skeletal Class I)...
October 18, 2018: Bulletin of Tokyo Dental College
Yuichiro Kikuchi, Ryuta Kimizuka, Tetsuo Kato, Katsuji Okuda, Eitoyo Kokubu, Kazuyuki Ishihara
Treponema denticola, an anaerobic spirochete found mainly in the oral cavity, is associated with periodontal disease and has a variety of virulence factors. Although in vitro studies have shown that T. denticola is able to penetrate epithelial cell monolayers, its effect on the epithelial barrier junction is not known. Human gingival epithelial cells are closely associated with adjacent membranes, forming barriers in the presence of tight junction proteins, including zonula occludens-1 (ZO-1), claudin-1, and occludin...
October 18, 2018: Bulletin of Tokyo Dental College
C N Guruprasad, A R Pradeep
Interleukin-34 (IL-34), an alternative ligand for macrophage colony-stimulating factor receptor, plays an important role in osteoclastogenesis. The aim of this study was to analyze the effect of smoking on IL-34 levels in gingival crevicular fluid (GCF) and plasma in individuals with healthy periodontium and chronic generalized periodontitis (CP). A total of 60 individuals ranging in age from 25 to 55 years were enrolled in the study. The participants were divided into 4 groups: Group A, 30 samples (15 GCF and 15 plasma) obtained from 15 non-smokers with healthy periodontium; Group B, 30 samples (15 GCF and 15 plasma) from 15 smokers with healthy periodontium; Group C, 30 samples (15 GCF and 15 plasma) from 15 non-smokers with CP; and Group D, 30 samples (15 GCF and 15 plasma) from 15 smokers with CP...
October 18, 2018: Bulletin of Tokyo Dental College
Takako Eguchi, Mihoko Tada, Takami Shiratori, Mitsue Imai, Yuki Onose, Seitaro Suzuki, Ryouichi Satou, Yoichi Ishizuka, Naoki Sugihara
The purpose of this study was to determine the distribution of healthy elderly individuals undergoing regular dental check-ups and identify any environmental or associated oral factors. A cross-sectional questionnaire survey was used to interview 216 individuals attending 2 welfare facilities for the elderly, of whom 160 were included in the final analysis. Items comprised age, sex, number of residual teeth, frequency of teeth/denture cleaning, subjective chewing ability, denture use, oral status, regular dental check-ups, visitation of the same dentist, number of dental visits in the past year, General Oral Health Assessment Index (GOHAI) (Japanese version) score, living situation, and use of routine medication...
October 18, 2018: Bulletin of Tokyo Dental College
Nobuharu Yamamoto, Takamichi Morikawa, Takashi Yakushiji, Takahiko Shibahara
An iliac block graft is the most commonly used biomaterial for reconstruction following resection of the mandible. Its use has some disadvantages, however, including limitations on the amount of bone that may be harvested, and the subsequent increase in burden on the iliac bone. Therefore, recently, free vascularized fibular grafts have been used as an alternative in some cases. Here, we report the advantages of, and issues related to reconstruction using free vascularized fibular grafts observed at Tokyo Dental College Chiba Hospital...
October 18, 2018: Bulletin of Tokyo Dental College
Mai Ohkubo, Takayuki Ueda, Hiroki Sugito, Akira Watanabe, Fumi Seshima, Toshiyuki Morioka, Yasutomo Yajima
A working group established at Tokyo Dental College Suidobashi Hospital considered how to manage patients experiencing difficulties with food intake during the process of dental treatment. This resulted in the opening of an in-hospital booth dedicated to providing advice on such problems. A survey was performed to determine the number of patients utilizing this facility and the department which they were attending with the aim of investigating factors involved in eating-related problems. The results revealed that patients were being referred to the booth from the departments of dental prosthetics, conservative dentistry, oral and maxillofacial surgery (by both dentists and dietitians), oral implantation, and orthodontics...
2018: Bulletin of Tokyo Dental College
Mika Otonari-Yamamoto, Kei Nakajima, Junichiro Sakamoto, Kenichi Imoto, Motoko Watanabe, Shinya Kotaki, Migiwa Kuroda, Kenichi Matsuzaka, Takahiko Shibahara, Hugh D Curtin, Tazuko K Goto
On images, a dermoid cyst is often described as resembling a "sack of marbles" or "marbles in a bag". Typically, it comprises an inhomogeneity filled with multiple nodules in a fluid matrix on both computed tomography and magnetic resonance imaging (MRI). How it appears, however, will vary depending on its histological contents, which may cause confusion in arriving at a diagnosis. This report describes a dermoid cyst in the floor of the mouth of a 55 year-old woman that showed an atypical internal appearance on MRI...
2018: Bulletin of Tokyo Dental College
Gentaro Mori, Takafumi Kobayashi, Taichi Ito, Yasutomo Yajima
Sjögren's syndrome (SS), an autoimmune disorder, affects the exocrine glands, including the lacrimal and salivary glands. It is characterized by symptoms of dry eye and dry mouth. As secretion of saliva decreases, patients with SS experience rampant caries, pain in the oral mucosa, inflammation and hardening of the salivary glands, abnormal taste, dysphagia, and loss of teeth earlier than healthy individuals. A removable partial denture is often used as a prosthesis after tooth loss. Compromised salivary lubrication, however, can produce traumatic ulceration of the mucosa, making use of a removable prosthesis in SS patients painful...
2018: Bulletin of Tokyo Dental College
Takeshi Onda, Kamichika Hayashi, Naoki Shiraishi, Nobuo Takano, Takahiko Shibahara
Verruciform xanthoma (VX), a papillary or wart-like lesion of the mucosa, is histopathologically characterized by papillary projection of the epithelium and an aggregation of foam cells in the lamina propria. Here, we describe a case of VX in the posterior mandibular gingiva, initially suspected to be a benign lesion based on clinical findings and cytology prior to an excisional biopsy. The patient was a 62-year-old man who had visited a local dentist approximately 1 year earlier, presenting with a white lesion in the left posterior mandibular gingiva that resisted removal by scraping...
2018: Bulletin of Tokyo Dental College
Masashi Eriguchi, Akira Watanabe, Kenichirou Suga, Youko Nakano, Teruo Sakamoto, Kenji Sueishi, Takeshi Uchiyama
The purpose of this study was to investigate the long-term effects of two-stage palatoplasty on the morphology of the maxillary alveolar arch and occlusion using plaster models of the maxilla and mandible obtained from patients with unilateral complete cleft lip and palate who also underwent orthodontic treatment. A total of 20 patients undergoing two-stage palatoplasty by Perko's method (Group T) were enrolled. Plaster models of the maxilla and mandible were obtained from each patient at Time 1, on commencement of orthodontic treatment in the mixed dentition period; at Time 2, on that of orthodontic treatment in the permanent dentition period; and at Time 3, on completion of active orthodontic treatment...
2018: Bulletin of Tokyo Dental College
Tetsuhide Makiguchi, Hiroki Imai, Aiko Arakawa, Ayako Tashiro, Takuro Yonezu, Seikou Shintani
The purpose of the present study was to investigate change in the size of the jaw and deciduous teeth in Japanese children over the past 40 years by performing measurements on plaster models of the dental arch obtained from children born between 2007 and 2009 (2000s group) and children born between 1968 and 1974 (70s) group. A total of 61 children were enrolled in the 2000s group, comprising 25 boys (average age, 4 years 5 months) and 36 girls (average age, 4 years 4 months), and 93 children in the 70s group, comprising 45 boys (4 years 6 months) and 48 girls (4 years 4 months)...
2018: Bulletin of Tokyo Dental College
Koichiro Ogami, Takayuki Ueda, Masahiro Ryu, Sayaka Tajima, Kaoru Sakurai
The tongue surface in older people requiring nursing care is often coated with a layer believed to comprise, keratinized products of degeneration, food residue, bacteria, and leukocytes attached to the tongue papillae. Which factors affect the status of this tongue coating remain to be elucidated, however. The purpose of this study was to evaluate factors related to tongue coating status in older people requiring nursing care. The study participants comprised 41 individuals admitted to special nursing homes for the elderly...
2018: Bulletin of Tokyo Dental College
Tadashi Kogou, Takashi Takaki, Takahiko Shibahara
Two-dimensional cephalometric analysis is commonly used in planning and evaluating the outcome of orthognathic surgery. It is difficult to arrive at an accurate evaluation with this method, however, as the jaw bones overlap in profile. Therefore, the purpose of this study was to use 3-dimensional (3-D) orthognathic treatment planning software for measurement of distances and angles to evaluate change in dentofacial morphology and stability after orthognathic surgery in patients with jaw deformity and facial asymmetry...
2018: Bulletin of Tokyo Dental College
Raghavendra S Medikeri, Vinayak Meharwade, Parikshit M Wate, Suresh V Lele
Immediate implant placement can be successful, even at infected sites. The adjunctive effects of concomitant use of platelet-rich fibrin (PRF) and decalcified freeze-dried bone allografts (DFDBA) at periapically infected sites remains to be determined, however. The purpose of this prospective study was to investigate the effect of combined use of PRF and DFDBA on immediate implant survival at tooth extraction sites exhibiting periapical lesions. Implants were immediately placed in 8 patients under a standard chemotherapeutic protocol...
2018: Bulletin of Tokyo Dental College
Toshihito Yoshimoto, Masamitsu Serikawa, Kazunari Higa, Kei Kitamura, Masaaki Kasahara, Masahito Yamamoto, Shinichi Abe
The objective of this study was to investigate the effects of mesenchymal cells on myoblasts in long-term cultivation of myoblast cell sheets. Sheets of myoblasts and mesenchymal cells from Japanese rabbit oral mucosa were generated and analyzed by histochemistry, Western blot, and reverse transcription-polymerase chain reaction. The presence of desmin and type IV collagen, which is seen in normal muscle tissue, was also confirmed in all the sheets produced. Expression of desmin and type IV collagen showed a decrease under co-culture conditions...
2018: Bulletin of Tokyo Dental College
C N Guruprasad, A R Pradeep
Interleukin (IL)-34 has recently been identified as an alternative ligand for colonystimulating factor-1 receptor and plays an important role in osteoclastogenesis. The aim of this study was to assess and compare IL-34 levels in gingival crevicular fluid (GCF) and plasma in obese individuals in the presence or absence of periodontal disease and to determine whether they showed a correlation with disease severity. Forty patients aged between 25 and 40 yr were enrolled and categorized into 4 groups: 10 non-obese patients with healthy periodontium (Group I); 10 obese patients with healthy periodontium (Group II); 10 non-obese patients with chronic periodontitis (Group III); and 10 obese patients with chronic periodontitis (Group IV)...
2018: Bulletin of Tokyo Dental College
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