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Anais da Academia Brasileira de Ciências

Raquel A C Leão, Vagner D Pinho, Artur S Coelho, Arthur E Kümmerle, Paulo R R Costa
New acylhydrazone-based palladacycles are prepared and evaluated as pre-catalysts in Mirozoki-Heck and oxyarylation reactions.
May 14, 2018: Anais da Academia Brasileira de Ciências
Luma G Magalhaes, Leonardo L G Ferreira, Adriano D Andricopulo
Cancer is one of the leading causes of death worldwide. With the increase in life expectancy, the number of cancer cases has reached unprecedented levels. In this scenario, the pharmaceutical industry has made significant investments in this therapeutic area. Despite these efforts, cancer drug research remains a remarkably challenging field, and therapeutic innovations have not yet achieved expected clinical results. However, the physiopathology of the disease is now better understood, and the discovery of novel molecular targets has refreshed the expectations of developing improved treatments...
May 14, 2018: Anais da Academia Brasileira de Ciências
Ariel A Beltramino, Roberto E Vogler, Alejandra Rumi, Leila B Guzmán, Stella M Martín, Juana G Peso
The exotic land gastropod Ovachlamys fulgens (Gude, 1900), aka the jumping snail, was registered in Eldorado city, Misiones province, constituting the first documented record of that species in Argentina-and for all of South America as well. Identities of the individuals were confirmed through morphological examination, and by a DNA sequencing of the cytochrome oxidase subunit I gene. DNA sequences for the mitochondrial 16S-rRNA and the nuclear 18S-rRNA genes were also obtained from the morphologically-confirmed specimens to gain insights into the genetic background of this species in Argentina, and as additional markers for enhancing the rapidity of identification by governmental authorities who are responsible for managing the presence of exotic species...
May 14, 2018: Anais da Academia Brasileira de Ciências
Leonardo O Medici, Fabíola V Gonçalves, Marcos Paulo S DA Fonseca, Salete A Gaziola, Daiana Schmidt, Ricardo A Azevedo, Carlos Pimentel
In this study, we are presenting recommendations to the best agricultural use as well as for plant breeding of three millet cultivars namely ENA1 and ENA2, which have African origin, and BRS1501 originally from India. These cultivars were evaluated for growth, yield and grain quality traits. The morphological traits evaluated in this study indicated that the African genotypes ENA1 and ENA2 are better than the Indian genotype BRS1501 for no-till farming or to produce forage with 15% of crude protein at flowering and at harvest to produce stover (around 7% of crude protein content) for livestock feeding...
May 14, 2018: Anais da Academia Brasileira de Ciências
Noelia S Ferrando, María C Claps, Hernán H Benítez, Néstor A Gabellone
In the present work, we provide the first approach about the life-history of Brachionus plicatilis in South America. We tested with laboratory experiments the response of the pampean strain of B. plicatilis for two of its main stressors (conductivity and temperature). We evaluated the effects of eight conductivity values from 1 to 17 and two temperatures (15 and 25 °C) to compare its abundance with those obtained in the pampean lotic and lentic environments, where this rotifer is frequent or dominant...
May 14, 2018: Anais da Academia Brasileira de Ciências
Carolina L Adam, Murilo Z Marochi, Setuko Masunari
A study on relative growth, sexual dimorphism and ontogenetic trajectory was carried out in a population of the aeglidAegla marginata coming from Barrinha River, Iguape River Basin, Tunas do Paraná, Paraná State, Brazil. The size the of morphological sexual maturity was estimated for males and females. The analysis of sexual dimorphism and ontogenetic trajectory were performed using geometric morphometric technique. Males reach maturity with 10.58 mm of carapace length (CL) and females with 10.38 mm CL. Sexual size dimorphism was only visible among adults, with males reaching larger sizes...
May 14, 2018: Anais da Academia Brasileira de Ciências
Nilza N Felizardo, Marcelo Knoff, Jessica B Diniz, Eduardo J L Torres, Flávia A A Calixto, Sérgio C São Clemente
From September 2014 to November 2015, 30 Paralichthys orbignyanus specimens were obtained from Sepetiba Bay in the municipality of Rio de Janeiro, State of Rio de Janeiro, Brazil. The fishes were necropsied and cestode larvae were recovered from the abdominal cavity, mesentery, and serosas of the stomach, intestine, spleen, liver, kidney and gonads. Nineteen fish were parasitized by a total of 90 trypanorhynch plerocerci. Based on morphological characters, these were identified as Pterobothrium crassicolle...
May 14, 2018: Anais da Academia Brasileira de Ciências
Ruiter L Morais, Mariângela F Santiago, Joachim W Zang, Warde A Fonseca-Zang, Fernando Schimidt
One of the most prominent fields of environmental chemistry is the study and the removal of micro-pollutants from aqueous matrices. Analytical techniques for their identification and quantification are becoming more sensitive and comprehensive and, as a result, an increasing number of drugs have been detected in environmental samples. However, the literature shows that conventional treatments for drinking water and wastewater are not sufficient for remove these compounds. This study aims to check whether the process of hydrothermal carbonization (CHT) is effective in removing the synthetic sex hormones: ethinyl estradiol, gestodene and cyproterone acetate from aqueous samples...
May 14, 2018: Anais da Academia Brasileira de Ciências
Reizaluamar J Neves, Rafael P Diniz, Eder J DE Oliveira
New techniques of rapid multiplication of cassava (Manihot esculenta Crantz) have been developed, requiring technical support for large-scale use. This work main to evaluate the agronomic performance of plantlets obtained by leaf buds technique against stem cuttings in the field conditions. The work was conducted using the randomized block design in a factorial scheme with 3 varieties (BRS Kiriris, 98150-06, 9624-09) × 4 origins of the plantlets (conventional - stem cuttings of 20 cm length, leaf buds of the upper, middle and inferior stem part) × 2 agrochemicals (control and treated)...
April 23, 2018: Anais da Academia Brasileira de Ciências
Samvel N Sirakanyan, Athina Geronikaki, Domenico Spinelli, Elmira K Hakobyan, Viktor G Kartsev, Anthi Petrou, Anush A Hovakimyan
Annulated thienopyrimidine derivatives attracted big interest of the scientific community due to their broad spectrum of biological activities among which are the inhibition of phosphodiesterase, antiproliferative and antimicrobial activities. As a continuation of our studies on the synthesis and biological activity of fused thieno[3,2-d]pyrimidine derivatives, the goal of this paper is the synthesis and study of the properties of compounds containing different heterocycles such as fused thieno[2,3-b]pyridine and tetrazolo[1,5-c]pyrimidine in the same molecule...
April 23, 2018: Anais da Academia Brasileira de Ciências
Rodrigo M DA Costa, Karina Karmirian, Stevens K Rehen
Neural development represents a dynamic process where mitochondrial integrity is decisive for neuronal activity. Structural changes in these organelles may be related to neurological disorders. Valproic acid (VPA) is an anticonvulsive drug commonly used for epilepsy treatment and its use is associated to increased risk of neuropsychiatric disorders. Recently we showed changes in shape and membrane potential in mitochondria from human neural progenitor cells (NPCs) exposed to VPA (da Costa et al. 2015). Here, we applied transmission electron microscopy and electron tomography to evaluate mitochondrial damage caused by VPA in NPCs...
April 23, 2018: Anais da Academia Brasileira de Ciências
Diego B Borin, Nathana J Mezzomo, Rodrigo A Vaucher, Guilherme DO Carmo, Luiz C Rodrigues Junior, Fernando B Sulczewski, Claiton I Schwertz, Ricardo E Mendes, Adriani P Damiani, Vanessa M DE Andrade, Virgínia C Rech, Carina R Boeck
Creatine acts intracellularly as energy buffer and storage, demonstrating protective effects in animal models of neurodegenerative diseases. However, its permeability throught blood-brain barrier (BBB) is reduced. The aim of the present study was developing a carrier to facilitate the delivery of creatine to the central nervous system. Creatine nanoliposomes were produced, characterized and assayed in models of toxicity in vitro and in vivo. Particles showed negative zeta potential (-12,5 mV), polydispersity index 0...
April 23, 2018: Anais da Academia Brasileira de Ciências
Luis Felipe Lima E Silva, Douglas C DE Souza, Luciane V Resende, Rita DE Cássia M R Nassur, Carolina Q Samartini, Wilson M Gonçalves
The objective of this study was to characterize the nutritional compounds of interest present in vegetables known as non-conventional, in Brazil. The following evaluations were carried out: antioxidant activity, phenolic compounds, vitamin C, calories, carbohydrates, humidity, lipids, proteins, fiber, acidity and quantification of minerals (P, K, Ca, Mg, S, Cu, Fe, Mn, Zn and B). The species studied were Amaranthus hybridus L., Amaranthus viridis L., Basella alba L., Eryngium campestre L., Hibiscus sabdariffa L...
April 23, 2018: Anais da Academia Brasileira de Ciências
Arnon H C Anésio, Márcia V Santos, Raul R Silveira, Evander A Ferreira, José B Dos Santos, Leandro D DA Silva
The aim of this work was to determine the persistence of auxinic herbicides applied on tropical pasture and toxicity for succeeding crops. The herbicides were applied in an area of dystrophic red‒yellow latosol with pasture infested of weeds. At 40, 80, and 280 days after application of herbicide, the soil samples were collected at depths of 0 to 20 cm. Soil with residues of 2,4-D, 2,4-D + picloram, triclopyr, and a soil without herbicide application were analyzed with six replicates. Seven crops were cultivated in these soils: cucumber (Cucumis sativus L...
April 23, 2018: Anais da Academia Brasileira de Ciências
Wendel C DE Sousa, Andressa T S Paz, Jamira D Rocha, Edemilson C DA Conceição, Luciane M DE Almeida, Lee C Chen, Leonardo L Borges, Elisa F L C Bailão
Costus spiralis is a Brazilian native plant used in popular medicine, but the safety of this therapeutic use needs investigation. So, the aim of this study was to evaluate the cytogenotoxic and antigenotoxic effects of C. spiralis leaves or stems aqueous extracts on Allium cepa root cells. Moreover, a phytochemical screening and an antioxidant and antifungal activities evaluation were performed. C. spiralis aqueous extracts presented cytotoxicity, but no mutagenicity was observed. When the antigenotoxicity was evaluated, C...
April 23, 2018: Anais da Academia Brasileira de Ciências
Danilo P Moreira-Junior, Valéria C Maia
As few Asilidae inventories of Rio de Janeiro areas have been published, there are many data gaps. This paper aims to contribute to the knowledge of richness, abundance and distribution of this family in this State. From January 2013 to March 2014, insects were collected monthly using Malaise traps and every two months using entomological nets in the Reserva Biológica União (REBIO), and Estação Ecológica Estadual de Guaxindiba (EEEG). 682 specimens of Asilidae were collected in the present study, distributed in 31 genera and 51 species (20 identified and 31 unidentified), 527 of REBIO (in 19 genera and 38 species - 14 identified and 24 unidentified), and 155 specimens of EEEG (in 12 genera and 19 species - 6 identified and 13 unidentified)...
April 23, 2018: Anais da Academia Brasileira de Ciências
Marcos Toebe, Letícia N Machado, Francieli L Tartaglia, Juliana O DE Carvalho, Cirineu T Bandeira, Alberto Cargnelutti Filho
The objective of this study was to determine the sample size necessary to estimate the mean and coefficient of variation in four species of crotalarias (C. juncea, C. spectabilis, C. breviflora and C. ochroleuca). An experiment was carried out for each species during the season 2014/15. At harvest, 1,000 pods of each species were randomly collected. In each pod were measured: mass of pod with and without seeds, length, width and height of pods, number and mass of seeds per pod, and mass of hundred seeds. Measures of central tendency, variability and distribution were calculated, and the normality was verified...
April 16, 2018: Anais da Academia Brasileira de Ciências
Antonio C B Burtoloso, Patrícia B Momo, Graziele L Novais
For many years diazocarbonyl compounds have been studied due to their versatility and usability in many chemical transformations. In this review, we summarize the traditional methods to prepare these compounds as well as the new methods and recent improvements in experimental procedures. Moreover, emergence of continuous flow techniques has allowed safer and environmentally friendly procedures for the handling of diazomethane and diazo compounds and will also be a topic in this review.
April 16, 2018: Anais da Academia Brasileira de Ciências
Silvia I R Franke, Patrícia Molz, Camila Mai, Joel H Ellwanger, Fernanda F Zenkner, Jorge A Horta, Daniel Prá
We evaluated the influence of hesperidin and vitamin C (VitC) on glycemic parameters, lipid profile, and DNA damage in male Wistar rats treated with sucrose overload. Rats were divided into six experimental groups: I-water control; II-sucrose control; III-hesperidin control; IV-VitC control; V-co-treatment of sucrose plus hesperidin; VI-co-treatment of sucrose plus VitC. We measured the levels of triglycerides, total cholesterol, HDL-c, LDL-c, fasting glucose, and glycated hemoglobin (A1C). DNA damage was evaluated in blood and brain cells using the comet assay and the micronucleus test was used to evaluate chromosomal damages in the rat bone marrow...
April 16, 2018: Anais da Academia Brasileira de Ciências
Érica F S Azevedo, Daniela R Costa E Silva, Tamires V S Natividade, Elane G Giese, Ana Rita DE Lima, Paola C Soares, Érika Branco
The wall of the diaphragm can be affected by changes caused by physical trauma, allowing the passage of viscera between the abdominal cavity and thoracic cavity, thus reducing the space for pulmonary expansion, leading to the formation of hernia and possible death. Thus, we aimed to characterize, size and determine the topography of the diaphragmatic muscle in the Southern Tamandua, since clinical and surgical activities in wild animals have become a reality more and more present in veterinary medicine. We used six adult animals, x-rayed and dissected, followed by collection of fragments of muscular portions for histological analysis...
April 16, 2018: Anais da Academia Brasileira de Ciências
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