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Journal of the National Medical Association

Moodithaya Shailaja, K M Damodara Gowda, Kedilaya Vishakh, N Suchetha Kumari
PURPOSE: Advanced age is associated with an accumulation of free radical damage, which leads to physiological and clinical modifications. Numerous pharmaceutical and nutraceuticals are considered to influence longevity and prompting healthy ageing. Therefore, the current study attempted to investigate Curcumin's role in the inflammatory indices as anti-ageing marker in albino Wistar rats. METHODS: Twelve months old rats were used in the study, grouped as Normal control (NC), Sham control (SC), Curcumin-1, Curcumin-2 and Curcumin-3...
April 2017: Journal of the National Medical Association
Cemil Kavalci, Muhittin Serkan Yilmaz, Afsin Emre Kayipmaz, Bahattin Isık, Elif Celikel, Gulsum Kavalci, Fevzi Yilmaz, Miray Ozlem, Bedriye Muge Sonmez, Selman Celebi
No abstract text is available yet for this article.
April 2017: Journal of the National Medical Association
Zilda Rogers
No abstract text is available yet for this article.
April 2017: Journal of the National Medical Association
Spencer Alexander Carter, Anna N Walker
Renal medullary carcinoma (RMC) is a rare but highly aggressive neoplasm that primarily affects young African Americans with sickle cell trait. Most patients present with macroscopic hematuria and have metastases at diagnosis. Chemotherapy, biologics directed against the more common renal cell carcinomas and radiation have all shown limited efficacy in treating patients with advanced RMC. We report two patients with RMC. Both had Stage IV disease. One underwent radical nephrectomy followed by radiation and biologic drug therapy but died five months later; the other underwent multiple cycles of chemotherapy plus anti-angiogenesis treatment but died 15 months after diagnosis...
April 2017: Journal of the National Medical Association
Tamrat M Retta, John Kwagyn, Otelio S Randall
Hypertension, a leading cause of cardiovascular morbidity and mortality worldwide, continues to challenge health professionals. There are too many patients with uncontrolled hypertension who end up with life altering or life ending complications. Over the years so much hypertension research has been conducted; and numerous effective antihypertensive drugs have been discovered and yet the rate of blood pressure control remains unacceptably low. It is high time that we focused our attention on the optimal use of the available knowledge and medications...
April 2017: Journal of the National Medical Association
Pedro A Poma
The growth of our population, especially the older than 65 segment, require more health providers. Moreover, compared to whites, persons of racial/ethnic minorities have less favorable clinical outcomes and this may be related to access to health care. Racial/ethnic concordance between physicians and patients improve outcomes and satisfaction with medical care. New medical schools have been opened, some schools have increased the size of the entering class, and there is the general desire to increase the enrollment and graduation of minority groups' physicians...
April 2017: Journal of the National Medical Association
Lea Baer, Sherise Chantell Rogers, Patricia Farrelly, Carmen Tornos, Keith Sweeney
Carcinomas arising from breast hamartomas are exceedingly rare. We present the first reported case of an African-American female presenting with a right breast lump and a subsequent mammogram suggestive of a hamartoma. She later underwent lumpectomy and was found to have HER2+ invasive ductal carcinoma (IDC) arising from a hamartoma. She was amenable to HER2-targeted trastuzumab, hormone therapy and adjuvant radiation but declined chemotherapy. In a review of the literature, IDC is the predominant neoplastic type found in hamartomas...
April 2017: Journal of the National Medical Association
Daniel P Verges, Hasan Dani, William A Sterling, Jeremy Weedon, William Atallah, Komal Mehta, David Schreiber, Jeffrey P Weiss, Nicholas T Karanikolas
PURPOSE: Several studies suggest that a baseline prostate specific antigen (PSA) measured in young men predicts future risk of prostate cancer. Considering recent recommendations against PSA screening, high-risk populations (e.g. black men, men with a high baseline PSA) may be particularly vulnerable in the coming years. Thus, we investigated the relationship between baseline PSA and future prostate cancer in a black majority-minority urban population. MATERIALS AND METHODS: A retrospective analysis was performed of the prostate biopsy database (n = 994) at the Brooklyn Veterans Affairs Hospital...
April 2017: Journal of the National Medical Association
Nneka S Udechukwu, Alan B Fleischer
Hidradenitis suppurativa (HS) is a chronic cutaneous inflammatory disease. Few reports have been published on the influence of race, ethnicity, and other patient demographic factors as determinants of care for HS. Data from the 2005 to 2011 National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medical Care Survey (NHAMCS) were analyzed for to assess factors that were predictive of outpatient visits for HS. Logistic regression controlling for demographic and other factors showed several disparities...
April 2017: Journal of the National Medical Association
Peter C Boettger, Charles L Knupp, Darla K Liles, Kaitlyn Walker
INTRODUCTION: Vitamin D levels in adult black Americans with sickle cell disease (SCD) are comparatively lower than those found in the general population of black Americans. The objectives of this study were to examine the prevalence of Vitamin D deficiency (VDD) in adults with various subtypes of sickle cell disease and identify risk factors for vitamin D deficiency. METHODS: In a retrospective study serum Vitamin D25(OH)D and/or VitaminD1,25(OH)2D levels were obtained in 120 subjects with sickle cell disease...
April 2017: Journal of the National Medical Association
Marshall H Chin
Deep-rooted structural problems drive health care disparities. Compounding the difficulty of attaining health equity, solutions in clinics and hospitals require the cooperation of clinicians, administrators, patients, and the community. Recent protests over police brutality and racism on campuses across America have opened fresh wounds over how best to end racism, with lessons for achieving health equity. Movement advocacy, the mobilizing of the people to raise awareness of an injustice and to advocate for reform, can break down ingrained structural barriers and policies that impede health equity...
April 2017: Journal of the National Medical Association
Benjamin Bowser, Robert Fullilove, Carl Word
Heroin abuse as an outcome of the prior use of painkillers increased rapidly over the past decade. This "new epidemic" is unique because the new heroin users are primarily young White Americans in rural areas of virtually every state. This commentary argues that the painkiller-to-heroin transition could not be the only cause of heroin use on such a scale and that the new and old heroin epidemics are linked. The social marketing that so successfully drove the old heroin epidemic has innovated and expanded due to the use of cell-phones, text messaging and the "dark web" which requires a Tor browser, and software that allows one to communicate with encrypted sites without detection...
April 2017: Journal of the National Medical Association
Irfan Yavasoglu, Gokhan Sargin, Fergun Yilmaz, Sermin Altındag, Gulsum Akgun, Anil Tombak, Bila Toka, Sinan Dal, Hasan Ozbas, Guven Cetin, Ayhan Donmez, Zeynep Arzu Yegin, Oktay Bilgir, Naci Tiftik, Sehmus Ertop, Orhan Ayyildiz, Mehmet Sonmez, Gokhan Pektas, Gurhan Kadıkoylu, Murat Tombuloglu, Zahit Bolaman
Low cholesterol levels may be accompanied by solid tumors or hematological malignancies such as multiple myeloma. Decreased cholesterol levels have been reported in some experimental studies about chronic lymphocytic leukemia (CLL). It may be associated with tumoral cell metabolism. Herein, we examine blood lipid profiles of patients with newly diagnosed CLL (284 male, 276 female, mean age 64 ± 11 years) as defined by National Cancer Institute criteria. The control group consisted of 71 healthy subjects with mean age 55 ± 9 years (28 male, 43 females)...
April 2017: Journal of the National Medical Association
Boluwaji Ogunyemi
Students of African ancestry often share an experience of being a racialized minority in the context of the educational institution. Late Professor of Anthropology John Ogbu's Cultural-ecological Theory of Academic Disengagement is employed to describe the negative responses encountered by peers in the name of academic achievement. The late Nigerian-American anthropologist John Ogbu described that it is often socially disadvantageous for black youth to prosper academically in formal education. Black students are often seen as betraying their cultural identities by aspiring to academic success and scholastic achievement and are met with repugnance by black peers...
April 2017: Journal of the National Medical Association
Bengur Taskiran, Guven B Cansu, Eylem Bahadir, Ruya Mutluay
Increased carotid intima media thickness indicates subclinical atherosclerosis. We evaluated the relation between vitamin D level and intima media thickness in patients with type 1 DM. 93 patients (female/male: 48/45, aged 31.5 ± 11.9 years, A1c 9.48 ± 2.43, vitamin D [15.9 (12.1-19.2)]) with type 1 DM were included into the study. Common carotid artery IMT was measured by real time B mode ultrasonography (MyLab 70 XVG, Esaote SpA, Genoa, Italy). Vitamin D was measured using radioimmunassay. Male and female patients (n = 14, 15%) had similar rates of plaque presence (p = 0...
April 2017: Journal of the National Medical Association
Richard Allen Williams
No abstract text is available yet for this article.
April 2017: Journal of the National Medical Association
Christopher J King, Yanique Redwood
The ongoing existence of institutionalized racism and discriminatory practices in various systems (education, criminal justice, housing, employment) serve as root causes of poor health in Blacks Lives. Furthermore, these unjust social structures and their complex interplay result in inefficient utilization of health services and reactive or futile interactions with medical providers. Collectively, these factors contribute to racial disparities in health and treatment represents a significant portion of the nation's health care expenditures...
May 2016: Journal of the National Medical Association
John M Fontaine, Sona M Franklin, Ashwani Gupta, Christina U Kang
No abstract text is available yet for this article.
May 2016: Journal of the National Medical Association
Yingqi Fan, Faping Wang, Suyun Li, Cheng Ye, Ying Ying, Hui Mao
Epithelioid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin that can arise in multiple and varied tissue sites. Pleural epithelioid hemangioendothelioma (PEH), a subtype of EHE, is particularly less reported. Herein, we describe a case of PEH presented with left-sided back pain in a 68-year-old female, and her chest CT scan revealed thickening of the left pleura and left pleural effusion, the histological diagnosis was confirmed by both conventional examination and immunohistochemistry. A literature search utilizing PubMed, Embase, Ovid and Cochrane, Wanfang and Chinese National Knowledge infrastructure (CNKI) for PEH was conducted to investigate the characteristics of the disease, 26 related articles were retrieved and 40 cases of PEH were reported...
May 2016: Journal of the National Medical Association
Oluwaseyi B Bolorunduro, Adekunle V Kiladejo, Islamiyat Babs Animashaun, Olakunle O Akinboboye
OBJECTIVES: To examine nationwide trends for racial disparities in Percutaneous Coronary Intervention after ST elevated Myocardial Infarction (STEMI). BACKGROUND: The Institute of Medicine (IOM) report published in 2002 showed that African Americans were less likely to receive coronary revascularization such as CABG and stents even after controlling for socioeconomics. It recommended increased awareness of these disparities among health professionals to reduce this...
May 2016: Journal of the National Medical Association
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