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Annali Dell'Istituto Superiore di Sanità

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https://www.readbyqxmd.com/read/28617266/sustainable-public-health-systems-for-rare-diseases
#1
Rita Maria Ferrelli, Amalia Egle Gentile, Marta De Santis, Domenica Taruscio
INTRODUCTION: In the framework of the Joint Action for Rare Diseases (RD-ACTION), a specific task was defined to identify mechanisms influencing sustainability, equity and resilience of health systems for rare diseases (RDs). METHOD: Literature narrative review on health systems sustainability and resilience for RDs. Years: 2000-2015. Databases: PubMed, Scopus, EBSCOHost, EMBAL, PASCAL, EMBASE, STN International and GoogleScholar. ANALYSIS: interpretive synthesis concept and thematic analysis (Dixon-Wood, et al...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617265/a-case-of-fulminant-subacute-sclerosing-panencephalitis-presenting-with-acute-myoclonic-astatic-epilepsy
#2
Fabio Magurano, Gian Luca Marella, Antonella Marchi, Antonietta Filia, Luigi Tonino Marsella, Saverio Potenza, Roberto Massa, Paola Bucci, Melissa Baggieri, Loredana Nicoletti
The neurologic sequelae post-measles are less common than other complications measles-related and can lead to severe disability or death: primary measles encephalitis (PME), acute post-infectious measles encephalomyelitis (APME), measles inclusion body encephalitis (MIBE), and subacute sclerosing panencephalitis (SSPE). SSPE syndrome can affect people years from the acute measles virus infection, as result of the persistence of defective viral particles in brain cells. Clinical onset typically manifests with progressive intellectual deterioration, behavioral changes, and myoclonic jerks...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617264/the-professional-quality-criteria-of-italian-breast-screening-radiologists-results-from-a-national-survey-comparing-the-programmes-started-in-2000-2012-versus-the-ones-started-in-1990-1999
#3
Doralba Morrone, Livia Giordano, Franca Artuso, Daniela Bernardi, Chiara Fedato, Alfonso Frigerio, Daniela Giorgi, Carlo Naldoni, Gianni Saguatti, Daniela Severi, Mario Taffurelli, Daniela Terribile, Leonardo Ventura, Lauro Bucchi
INTRODUCTION: In Italy, due to increasing healthcare budget and staff shortages, the recently created regional mammography screening programmes were established under worse radiology practice quality criteria than the previously created programmes. METHODS: Using available data from a national questionnaire survey conducted at the end of 2013 and involving 222 responder radiologists, we compared the main professional quality standards of radiologists working in the screening programmes established during the period 2000-2012 with those working in the screening programmes created from 1990 to 1999...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617263/vaccine-hesitancy-parental-professional-and-public-responsibility
#4
Maria Luisa Di Pietro, Andrea Poscia, Adele Anna Teleman, Davide Maged, Walter Ricciardi
The opposition to vaccinations is a well-known phenomenon that dates back to the Victorian age when it was self-limited by the awareness of the importance to be protected against fearsome infectious diseases. In the XX century, the mass use of vaccination has - instead - consented to eradicate or drastically reduce the burden of diseases such as smallpox and polio. These positive effects of the vaccination campaigns have blurred out, if not erased, the memory of the tragic consequences of the past's widespread diseases, leading people to underestimate the severity of the harm that vaccinations prevent...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617262/mmr-vaccine-in-the-postpartum-does-not-expose-seronegative-women-to-untoward-effects
#5
Enrico Finale, Giuliana Leonardi, Gaetano Auletta, Roberta Amadori, Chiara Saglietti, Leonardo Pagani, Andrea Guala
BACKGROUND: The aim of this study was to assess whether rubella vaccination immediately after delivery could expose seronegative women to specific untoward effects. METHODS: 163 rubella-seronegative women received Measles-Mumps-Rubella (MMR) vaccine in the immediate postpartum period; they were evaluated at one month and at three months thereafter through telephone interviews. As controls, we matched 163 rubella-seropositive women, who might experience similar symptoms for any reason in the same timeframe...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617261/health-promotion-theories-in-nutritional-interventions-for-community-dwelling-older-adults-a-systematic-review
#6
Barbara Raffaele, Maria Matarese, Rosaria Alvaro, Maria Grazia De Marinis
OBJECTIVE: To identify theories applied in interventions promoting healthy nutrition among community-dwelling older adults and determine the efficacy of theories in changing knowledge, attitudes, and behaviors. MATERIAL AND METHODS: The PubMed, PsycINFO, Embase, and ERIC databases were searched for English articles from January 1990 to December 2015. Mono or multicomponent randomized controlled trial studies were included, whereas research on nutritional interventions related to acute or chronic diseases were excluded...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617260/pes-planus-and-pes-cavus-in-southern-italy-a-5-years-study
#7
Gianmarco Troiano, Nicola Nante, Guglielmo Lucio Citarelli
INTRODUCTION: Baropodometrical digital techniques map the pressures exerted on the foot plant during both static and dynamic loadings. The study of the distribution of such pressures makes it possible to evaluate the postural and locomotory biomechanics together with its pathological variations. METHODS: From January 2011 to August 2016 we conducted a cross sectional study in order to diagnose flatfoot and hollowfoot through the baropodometric analysis, and collecting additional information such as gender and the age...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617259/trend-and-variability-in-open-and-laparoscopic-hysterectomies-for-patients-with-benign-disease-a-retrospective-cohort-study
#8
Mario Saia, Alessandra Buja, Erich Cosmi, Domenico Mantoan, Vincenzo Baldo
AIM: The aim of the present analysis on a regional hospital database was to ascertain the variability and 5-year trends of hysterectomy rates and the different surgical approaches used. METHODS: A retrospective cohort study was conducted in Veneto Region (North-East Italy), based on administrative data collected in 6 years, from 2009 to 2014. RESULTS: Our study showed an overall decline in the hospitalization rates for hysterectomy from 197...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617258/micronized-palmitoylethanolamide-trans-polydatin-treatment-of-endometriosis-related-pain-a-meta-analysis
#9
Ugo Indraccolo, Salvatore Renato Indraccolo, Fiorenzo Mignini
AIM: To demonstrate clinical effectiveness of micronized palmitoylethanolamide-trans-polydatin combination in reducing endometriotic chronic pelvic pain. Other endometriotic-pains were also assessed. METHODS: Systematic reviews of PubMed, SCIELO, Scopus, and AJOL. Randomized trials and observational studies reporting a visual analogue scale for pain or similar in endometriotic patients were reviewed. A mean improvement of visual analogue scale (or visual analogue scale-like) scores at enrollment and at a three-month follow-up was assessed and interpreted clinically...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617257/do-italian-pregnant-women-use-periconceptional-folate-supplementation
#10
Alice Maraschini, Paola D'Aloja, Ilaria Lega, Marta Buoncristiano, Ursula Kirchmayer, Martina Ventura, Serena Donati
INTRODUCTION: Deficiency of folic acid (FA) has been identified as a risk factor for neural tube defects (NTDs) as well as other congenital anomalies. Thus, periconceptional folate supplementation is recommended for all women planning to get pregnant. METHODS: We conducted a KAP (knowledge, attitude, practice) survey to investigate the use of FA and its appropriateness. The survey included a sample of 562 women who delivered in the Lazio region between 2013 and 2014...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617256/mortality-of-populations-residing-in-geothermal-areas-of-tuscany-during-the-period-2003-2012
#11
Elisa Bustaffa, Fabrizio Minichilli, Daniela Nuvolone, Fabio Voller, Francesco Cipriani, Fabrizio Bianchi
INTRODUCTION: The limited scientific knowledge on the relationship between exposure and health effects in relation to geothermal activity motivated an epidemiologic investigation of Tuscan geothermal area. AIM: This study aims at describing mortality of populations living in Tuscan municipalities in the period 2003-2012. METHOD: Sixteen municipalities were included in the study area: eight in the northern and eight in the southern area. Mortality data come from the Regional Mortality Registry of Tuscany...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617255/a-harmonized-and-efficient-clinical-research-environment-would-benefit-patients-and-enhance-european-competitiveness-commentary
#12
Antonino Amato, Eugenio Aringhieri, Stefania Boccia, Filippo Buccella, Barbara Gorini, Donatella Gramaglia, Riccardo Masetti, Paolo Rossi, Pier Giuseppe Pelicci
The forthcoming implementation of the European Clinical Trial Regulation (Regulation (EU) No. 536/2014), which is expected to facilitate the conduct of clinical trials across the European Union, will require National Authorities to create the best conditions for the implementation of the new Regulation through national guidelines, so that sponsors may reconsider Europe as a prime location for planning clinical trials. During a meeting titled "Innovation in Clinical Research", an expert panel discussed potential local advances fostering competitiveness of European clinical research with representatives of the pharmaceutical industry, patient organisations and Italian regulatory agency in view of the forthcoming implementation of (EU) No...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617254/pertussis-in-infants-and-the-resurgence-of-a-vaccine-preventable-disease-what-to-do-commentary
#13
Giorgio Fedele, Paola Stefanelli
Pertussis or whooping cough remains one of the most poorly controlled vaccine-preventable diseases across the world. Universal vaccination has dramatically reduced its incidence but has failed to bring it completely under control. In the last decades, changes in pertussis epidemiology have been noted, likely related to the introduction of acellular pertussis vaccines. Increasing incidence is recorded among adolescents and adults who have become a reservoir for transmission to unimmunized infants, who are at risk of severe disease and death...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617253/the-emerging-role-of-the-human-bone-marrow-as-a-privileged-developmental-niche-for-the-transmission-stages-of-the-malaria-parasite-plasmodium-falciparum-commentary
#14
Pietro Alano
The spread of malaria relies on the ability of the Plasmodium parasites to be transmitted from infected individuals to the Anopheles mosquito vectors. Recent work on the most lethal of the malaria parasites, Plasmodium falciparum, identified the infected human bone marrow as a preferential site for the localization and maturation of the parasite transmission stages, the gametocytes. These findings unveil a complex host parasite interplay and an unsuspected role of the bone marrow microenvironment in the successful transmission of the malaria parasite and have major implications in developing and targeting future interventions to block the transmission of P...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617252/patient-physician-alliance-from-hippocrates-to-post-genomic-era-commentary
#15
Simonetta Pulciani, Domenica Taruscio
Patients need clinical competence, appropriate diagnosis and therapies in overcoming their disease. Yet this is insufficient. The illness experience tends to frighten people and the resulting emotional aspects could become relevant factors in coping with a sickness and disability. Hippocrates was the first to urge physicians to look beyond the physical features of diseases and to consider the patient as a unique psychosomatic entity. Additionally, the scientist spurred physicians to make the patient an active participant in combating the disease...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28617251/on-transparency-in-health-care-guidelines-editorial
#16
Carlo Petrini, Enrico Alleva
No abstract text is available yet for this article.
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361810/educational-action-in-the-rehabilitation-of-severe-acquired-brain-injuries-the-role-of-self-awareness
#17
Daniela Silvestro, Maria Mazzetti, Chiara Melia, Maria Teresa Stagno, Giovanni Augusto Carlesimo, Umberto Bivona, Rita Formisano
Severe acquired brain injuries (ABI) cause a range of short-or long-term limitations in physical and neuropsychological abilities. The aim of rehabilitation is to promote the harmonious development of the individual through collaboration between medical and educational sciences, involved in the educability of the whole person, in which the aim is not only functional recovery but also social-reintegration. This "functional synergy" permits the development of the person, and establishes an indissoluble link between functions and attitudes, thus allowing the achievement of the greater possible autonomy...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361809/association-of-non-alcoholic-fatty-liver-disease-and-cardiometabolic-risk-factors-with-early-atherosclerosis-in-an-adult-population-in-southern-italy
#18
Carmelo Antonio Caserta, Alfonso Mele, Pasquale Surace, Luigina Ferrigno, Angela Amante, Arianna Messineo, Carmelo Vacalebre, Fulvia Amato, Damiano Baldassarre, Mauro Amato, Fabrizio Marcucci, Massimo Zuin
AIM: The prevalence of risk factors for cardiovascular and metabolic diseases was investigated in an adult population of the city of Cittanova, Southern Italy. METHODS: The study was conducted among 992 randomly selected adults aged 18-75 years, between April 2009 and January 2011. RESULTS: Prevalence rates of non-alcoholic fatty liver disease (NAFLD), overweight, obesity, and metabolic syndrome (MS) were 24.8%, 41.5%, 27.1%, and 34.4%, respectively...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361808/appropriateness-and-efficacy-of-spa-therapy-for-musculoskeletal-disorders-a-delphi-method-consensus-initiative-among-experts-in-italy
#19
Marco Paoloni, Andrea Bernetti, Ovidio Brignoli, Daniela Coclite, Antonio Fraioli, Stefano Masiero, Antonello Napoletano, Nicola Quirino, Franco Rengo, Carlo Ruosi, Ugo Viora, Marco Vitale, Valter Santilli
OBJECTIVE: The aim of the study was to identify the main aspects concerning appropriateness and efficacy of Spa therapy for musculoskeletal pathologies. METHODS: A committee of 8 experts from Italian universities, public hospitals, territorial services, research institutes and patient associations was set up. Clinicians from Italian medical centers specialized in rheumatology, rehabilitation and thermal medicine took part in a Delphi process aimed at obtaining consensus statements among the participants...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361807/the-italian-reference-sites-of-the-european-innovation-partnership-on-active-and-healthy-ageing-progetto-mattone-internazionale-as-an-enabling-factor
#20
Maddalena Illario, Vincenzo De Luca, Giovanni Tramontano, Enrica Menditto, Guido Iaccarino, Lorenzo Bertorello, Ernesto Palummeri, Valeria Romano, Giuliana Moda, Marcello Maggio, Mirca Barbolini, Lisa Leonardini, Antonio Addis
BACKGROUND: Ageing population implies an increasing demand for health care services and resources, unsustainable according to current previsions. The European Commission is tackling this challenge throughout initiatives such as the European Innovation Partnership on Active and Healthy Ageing (EIP-AHA), where all the efforts are aligned to the common goal of adding two active and healthy years to the life of European Union (EU) citizens. METHOD: We presented the collaborative efforts of Italian Reference Site Collaborative Network 2012-2015...
January 2017: Annali Dell'Istituto Superiore di Sanità
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