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Annali Dell'Istituto Superiore di Sanità

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https://www.readbyqxmd.com/read/28361810/educational-action-in-the-rehabilitation-of-severe-acquired-brain-injuries-the-role-of-self-awareness
#1
Daniela Silvestro, Maria Mazzetti, Chiara Melia, Maria Teresa Stagno, Giovanni Augusto Carlesimo, Umberto Bivona, Rita Formisano
Severe acquired brain injuries (ABI) cause a range of short-or long-term limitations in physical and neuropsychological abilities. The aim of rehabilitation is to promote the harmonious development of the individual through collaboration between medical and educational sciences, involved in the educability of the whole person, in which the aim is not only functional recovery but also social-reintegration. This "functional synergy" permits the development of the person, and establishes an indissoluble link between functions and attitudes, thus allowing the achievement of the greater possible autonomy...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361809/association-of-non-alcoholic-fatty-liver-disease-and-cardiometabolic-risk-factors-with-early-atherosclerosis-in-an-adult-population-in-southern-italy
#2
Carmelo Antonio Caserta, Alfonso Mele, Pasquale Surace, Luigina Ferrigno, Angela Amante, Arianna Messineo, Carmelo Vacalebre, Fulvia Amato, Damiano Baldassarre, Mauro Amato, Fabrizio Marcucci, Massimo Zuin
AIM: The prevalence of risk factors for cardiovascular and metabolic diseases was investigated in an adult population of the city of Cittanova, Southern Italy. METHODS: The study was conducted among 992 randomly selected adults aged 18-75 years, between April 2009 and January 2011. RESULTS: Prevalence rates of non-alcoholic fatty liver disease (NAFLD), overweight, obesity, and metabolic syndrome (MS) were 24.8%, 41.5%, 27.1%, and 34.4%, respectively...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361808/appropriateness-and-efficacy-of-spa-therapy-for-musculoskeletal-disorders-a-delphi-method-consensus-initiative-among-experts-in-italy
#3
Marco Paoloni, Andrea Bernetti, Ovidio Brignoli, Daniela Coclite, Antonio Fraioli, Stefano Masiero, Antonello Napoletano, Nicola Quirino, Franco Rengo, Carlo Ruosi, Ugo Viora, Marco Vitale, Valter Santilli
OBJECTIVE: The aim of the study was to identify the main aspects concerning appropriateness and efficacy of Spa therapy for musculoskeletal pathologies. METHODS: A committee of 8 experts from Italian universities, public hospitals, territorial services, research institutes and patient associations was set up. Clinicians from Italian medical centers specialized in rheumatology, rehabilitation and thermal medicine took part in a Delphi process aimed at obtaining consensus statements among the participants...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361807/the-italian-reference-sites-of-the-european-innovation-partnership-on-active-and-healthy-ageing-progetto-mattone-internazionale-as-an-enabling-factor
#4
Maddalena Illario, Vincenzo De Luca, Giovanni Tramontano, Enrica Menditto, Guido Iaccarino, Lorenzo Bertorello, Ernesto Palummeri, Valeria Romano, Giuliana Moda, Marcello Maggio, Mirca Barbolini, Lisa Leonardini, Antonio Addis
BACKGROUND: Ageing population implies an increasing demand for health care services and resources, unsustainable according to current previsions. The European Commission is tackling this challenge throughout initiatives such as the European Innovation Partnership on Active and Healthy Ageing (EIP-AHA), where all the efforts are aligned to the common goal of adding two active and healthy years to the life of European Union (EU) citizens. METHOD: We presented the collaborative efforts of Italian Reference Site Collaborative Network 2012-2015...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361806/association-between-serum-vitamin-d-and-metabolic-syndrome-in-middle-aged-and-older-adults-and-role-of-supplementation-therapy-with-vitamin-d
#5
Walter Verrusio, Paola Andreozzi, Alessia Renzi, Marco Musumeci, Nicolò Gueli, Mauro Cacciafesta
OBJECTIVES: To evaluate i) the correlation between vitamin D (vit. D) serum concentrations and metabolic syndrome (MetS); ii) the efficacy of 6 months supplementation therapy with vit. D. METHOD: 200 patients were enrolled. Blood analyses and anthropometric measurements were carried out. Patients with hypovitaminosis D received an oral supplement therapy. RESULTS: 81% of the sample shows vit. D levels < 30 ng/mL. Rate of MetS was significantly higher in vit...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361805/hospital-efficiency-how-to-spend-less-maintaining-quality
#6
Paolo Campanella, Elena Azzolini, Alessio Izzi, Ferruccio Pelone, Concetta De Meo, Daniele La Milia, Maria Lucia Specchia, Walter Ricciardi
INTRODUCTION: The recent global economic crisis is pushing governments worldwide to obtain a more explicit and urgent rationing of resources. The purpose of this study is to provide, through Data Envelopment Analysis (DEA), a methodological framework useful for investigating technical efficiency of hospital care. METHODS: To validate such framework, we compared 50 Italian public hospital trusts (AOs) to identify relative efficient using inputs and outputs from national databases...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361804/risk-adjusted-mortality-after-hip-replacement-surgery-a-retrospective-study
#7
Gabriele Messina, Silvia Forni, Daniele Rosadini, Manuele Falcone, Francesca Collini, Nicola Nante
INTRODUCTION: Hip replacement (HR) operations are increasing. Short term mortality is an indicator of quality; few studies include risk adjustment models to predict HR outcomes. We evaluated in-hospital and 30-day mortality in hospitalized patients for HR and compared the performance of two risk adjustment algorithms. MATERIALS AND METHODS: A retrospective cohort study on hospital discharge records of patients undergoing HR from 2000 to 2005 in Tuscany Region, Italy, applied All-Patient Refined Diagnosis Related Groups (APR-DRG) and Elixhauser Index (EI) risk adjustment models to predict outcomes...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361803/illicit-drugs-in-emergency-department-patients-injured-in-road-traffic-accidents
#8
Pietro Papa, Loretta Rocchi, Laura Maria Rolandi, Marcello Di Tuccio, Marco Biffi, Antonella Valli
Urine and blood samples from 1730 drivers involved in road accidents (July 2012 - December 2015) were analyzed for the evaluation of driving under influence of drug of abuse according to the Lombardia Region guideline. The 22.5% (95% CI 20.5 to 24.5) of urine screenings tested positive for at least one class of drugs. 10.6% (95% CI 9.2 to 12.1) of the 1730 drivers were under the influence of drug, being blood concentration above the cut-off limit for at least one active substance; the proportion of illicit drugs in blood was cocaine 5...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361802/molecular-characterization-of-babesia-and-theileria-species-in-ticks-collected-in-the-outskirt-of-monte-romano-lazio-region-central-italy
#9
Luciano Toma, Marco Di Luca, Fabiola Mancini, Francesco Severini, Carmela Mariano, Giancarlo Nicolai, Valentina Laghezza Masci, Alessandra Ciervo, Anna Maria Fausto, Simone Mario Cacciò
BACKGROUND: In 2012-2013, an investigation was carried out in the Viterbo province, Lazio region, on ticks and tick-borne Apicomplexan protozoa of the Babesia and Theileria genera. This followed the reporting of high density of ticks by soldiers operating in a military shooting range, and the signaling by owners and local veterinary authorities of several cases of babesiosis among cattle. METHODS: A total of 422 ticks were collected from 35 heads, whereas 96 ticks were collected by dragging...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361801/uterus-transplants-and-their-ethical-implications
#10
Carlo Petrini, Assuntina Morresi
Early experiments in womb transplants have increased interest in the possibility of performing this procedure in women who have no womb, usually for congenital reasons. The present article describes past experiments and summarises the most relevant reference documents before indicating the key ethical implications involved in womb transplants.
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361800/the-product-of-the-human-ahi-1-abelson-helper-integration-site-gene-experimental-in-vitro-data-point-to-its-involvement-in-tumor-cell-invasion
#11
Giuseppina Bozzuto, Agnese Molinari
INTRODUCTION: Each of the steps involved in invasion of tumors requires specific molecular program in which the modulation of adhesive and migratory properties of disseminating cells plays an essential role. The improvement in the knowledge of these mechanisms can lead to discovery of new target candidates in drug development. In this study we focused attention on the product of the human AHI-1 (Abelson helper integration site) gene Jouberin (Jbn). METHODS: In particular, we explore by in vitro invasion assay, AHI-1 knockdown and electron microscopy, if Jbn is involved in the signaling machinery that regulates tumor invasion...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361799/do-i-need-training-in-public-health-ethics-a-survey-on-italian-residents-beliefs-knowledge-and-curricula
#12
Massimiliano Colucci, Martina Chellini, Paola Anello, Benedetto Arru, Glenda Tettamanti, Elena Marcon
INTRODUCTION: Ethics is needed to support the decision-making process in public health and to face moral issues during practice. However, professionals are often not adequately trained. OBJECTIVES: In 2015, the National Conference of Public Health Medical Residents of the Italian Society of Public Health started the "Public Health Ethics" workgroup to evaluate how the Italian Schools of Public Health train their residents in ethics, and which are residents' beliefs, knowledge and attitudes about public health ethics...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361798/research-on-biological-materials-of-human-origin-jurists-and-scientists-face-to-face-commentary
#13
Carlo Petrini, Walter Ricciardi
On 3rd October 2016 a convention was held in the Aldo Moro room of the Chamber of Deputies on "Research on biological materials of human origin. Jurists and scientists face to face". The convention was organised by the Bioethics Unit of the Istituto Superiore di Sanità (ISS, Italian National Institute of Health) in conjunction with the Italian Academy of the Internet Code (IAIC) and the Fondazione Centro di Iniziativa Giuridica Piero Calamandrei. The present contribution reports the topics discussed and the key conclusions reached...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361797/knowledge-and-participation-moving-towards-scientific-citizenship-editorial
#14
Fabrizio Rufo
No abstract text is available yet for this article.
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28361796/why-research-on-endocrine-disrupting-chemicals-is-still-worthwhile-editorial
#15
Alberto Mantovani
No abstract text is available yet for this article.
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/27999235/drug-resistant-tuberculosis-in-naples-2008-2013
#16
Annalisa Del Giudice, Alessandro Mustazzolu, Angelo Iacobino, Rossella Perna, Riccardo Smeraglia, Rachele Marino, Lanfranco Fattorini, Giulia Santoro
BACKGROUND: Drug-resistant tuberculosis (TB) is a serious threat in industrialized countries, but information from Southern Italy is lacking. Here, we present the results of a retrospective study of TB cases diagnosed in 2008-2013 in Naples, the largest city in Southern Italy. METHODS: Six hundred ninety Mycobacterium tuberculosis strains were isolated at the Ospedali dei Colli of Naples, and resistance to first-line and second-line drugs was determined. RESULTS: Multidrug-resistant (MDR) TB increased from 2008 to 2013, with 77...
October 2016: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/27999234/teleretinography-into-diabetes-integrated-care-an-italian-experience
#17
Roberto Perilli, Rosamaria Di Biagio, Renato Seller, Luigi Ruotolo, Carla Granchelli, Valeria Marisi, Stefania Melena, Agostino Consoli
INTRODUCTION: Integrated care, by allowing information exchange among health professionals, improves outcomes and favours a reduction in hospital admission in diabetes. Retinal complications can be sight-threatening, and diabetic patients often miss the suggested yearly clinical examination. METHODS: Teleretinography can be easily performed in patients attending Diabetes Clinics: images are sent to a remote ophthalmologist, grading and instructions are received and forwarded to General Practitioners by a dedicated software...
October 2016: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/27999233/smallpox-as-an-actual-biothreat-lessons-learned-from-its-outbreak-in-ex-yugoslavia-in-1972
#18
Elizabeta Ristanovic, Ana Gligic, Sonja Atanasievska, Vesna Protic-Djokic, Dragutin Jovanovic, Miodrag Radunovic
Variola (smallpox) virus is classified as class A of potential biological weapons, due to its microbiological, genetic, antigenic and epidemiological characteristics. The potential danger is more real because vaccination against smallpox has stopped since disease eradication in 1979. That is why we want to share our unique, rich experience and acquired knowledge in the fight against this highly contagious and deadly disease during the smallpox outbreak in ex-Yugoslavia in 1972. It was the largest postwar outbreak in Europe when there were officially registered 175 ill patients, 35 of them with lethal outcome...
October 2016: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/27999232/the-relationship-between-medical-ethics-and-the-legal-system-in-italy-food-for-thought
#19
Carlo Petrini, Walter Ricciardi
Relations between ethics in general - and medical ethics in particular - and legal systems are complex and have been extensively examined in the literature. The topic is important not only for ethicists and jurists, but also for members of the public, who benefit from the services offered by the professions. While the Italian Institute of Health does not claim to propose new avenues for exploration of the relations between ethics and legal systems, it offers some food for thought in the ongoing debate.
October 2016: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/27999231/adverse-reproductive-outcomes-associated-with-exposure-to-a-municipal-solid-waste-incinerator
#20
Michele Santoro, Fabrizio Minichilli, Nunzia Linzalone, Alessio Coi, Maria Teresa Maurello, Domenico Sallese, Fabrizio Bianchi
INTRODUCTION: The association between reproductive health outcomes and exposure to municipal solid waste incinerators (MSWIs) is inconclusive. This study investigates the association between exposure to a MSWI and various reproductive outcomes (preterm birth, low birth weight, small for gestational age, and sex ratio), taking into account other sources of pollution (industrial plants, highway, major roads with high traffic flows) and maternal factors, including the socioeconomic status...
October 2016: Annali Dell'Istituto Superiore di Sanità
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