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American Journal of Drug and Alcohol Abuse

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https://www.readbyqxmd.com/read/29333890/cigarette-smoking-and-quit-attempts-among-latinos-in-substance-use-disorder-treatment
#1
Anna Pagano, Noah Gubner, Thao Le, Joseph Guydish
BACKGROUND: Differences in tobacco use behaviors have been identified between Latinos and non-Latino whites in the general US population. Little is known about cigarette smoking and quitting behaviors of Latinos in treatment for substance use disorders (SUDs), who represent two major tobacco-vulnerable groups. OBJECTIVES: To compare, in a national sample of persons enrolled in SUD treatment, demographic, drug use, and smoking and quitting prevalence and behaviors between Latinos and non-Latino whites...
January 15, 2018: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29333880/pharmacogenetic-analysis-of-opioid-dependence-treatment-dose-and-dropout-rate
#2
Richard C Crist, James Li, Glenn A Doyle, Alex Gilbert, Bryan M Dechairo, Wade H Berrettini
BACKGROUND: Currently, no pharmacogenetic tests for selecting an opioid-dependence pharmacotherapy have been approved by the US Food and Drug Administration. OBJECTIVES: Determine the effects of variants in 11 genes on dropout rate and dose in patients receiving methadone or buprenorphine/naloxone (ClinicalTrials.gov Identifier: NCT00315341). METHODS: Variants in six pharmacokinetic genes (CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4) and five pharmacodynamic genes (HTR2A, OPRM1, ADRA2A, COMT, SLC6A4) were genotyped in samples from a 24-week, randomized, open-label trial of methadone and buprenorphine/naloxone for the treatment of opioid dependence (n = 764; 68...
January 15, 2018: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29286835/drug-use-patterns-and-predictors-among-homeless-youth-results-of-an-ecological-momentary-assessment
#3
Diane Santa Maria, Nikhil Padhye, Yijiong Yang, Kathryn Gallardo, Glenn-Milo Santos, Julie Jung, Michael Businelle
BACKGROUND: Alcohol and drug use is associated with significant morbidity and mortality and is highly prevalent among homeless youth. Ecological Momentary Assessments (EMA) have been used to examine the effect of urges on drug use, though not among homeless youth. OBJECTIVES: We assessed the patterns of drug use and the correlation between real-time contextual factors and drug use using EMA collected daily. We identified predictors of drug use among a sample of homeless youth 18-25 years old in Houston, Texas...
December 29, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29261344/patterns-of-simultaneous-and-concurrent-alcohol-and-marijuana-use-among-adolescents
#4
Megan E Patrick, Deborah D Kloska, Yvonne M Terry-McElrath, Christine M Lee, Patrick M O'Malley, Lloyd D Johnston
BACKGROUND: Alcohol and marijuana are the most commonly used substances among adolescents but little is known about patterns of co-use. OBJECTIVES: This study examined patterns of concurrent (not overlapping) and simultaneous (overlapping) use of alcohol and marijuana among adolescents. METHODS: Data from US-national samples of 12th graders (N = 84,805, 48.4% female) who participated in the Monitoring the Future study from 1976 to 2016 and who used alcohol and/or marijuana in the past 12 months were used to identify latent classes of alcohol use, marijuana use, and simultaneous alcohol and marijuana (SAM) use...
December 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29261341/benefit-requirements-for-substance-use-disorder-treatment-in-state-health-insurance-exchanges
#5
Bikki Tran Smith, Kathleen Seaton, Christina Andrews, Colleen M Grogan, Amanda Abraham, Harold Pollack, Peter Friedmann, Keith Humphreys
BACKGROUND: Established in 2014, state health insurance exchanges have greatly expanded substance use disorder (SUD) treatment coverage in the United States as qualified health plans (QHPs) within the exchanges are required to conform to parity provisions laid out by the Affordable Care Act and the Mental Health Parity and Addiction Equity Act (MHPAEA). Coverage improvements, however, have not been even as states have wide discretion over how they meet these regulations. OBJECTIVE: How states regulate SUD treatment benefits offered by QHPs has implications for the accessibility and quality of care...
December 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29261329/the-impact-of-stepfamily-relationship-quality-on-emerging-adult-non-medical-use-of-prescription-drugs
#6
Kaitlin P Ward, Cory B Dennis, Gordon E Limb
BACKGROUND: Emerging adults aged 18 to 25 are most at-risk for non-medical use of prescription drugs (NMUPD). While the literature dedicated to emerging-adult NMUPD has explored risk and protective factors at an individual level, much less is known regarding how interpersonal and familial factors relate to NMUPD. Because interpersonal bonds can have a significant impact on behavior, familial factors may be important predictors of NMUPD among emerging adults. OBJECTIVES: Inasmuch as growing up in a stepfamily is increasingly common for children, this study aimed to determine whether perceived stepfamily quality within three stepfamily subsystems - child-biological parent, child-stepparent, and child-stepsibling - decreased the likelihood of NMUPD in emerging adulthood...
December 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29215917/breaking-the-cycle-of-opioid-use-disorder-with-ibogaine
#7
Deborah C Mash
No abstract text is available yet for this article.
December 7, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29194003/mediating-effect-of-deviant-peers-on-the-relationship-between-sensation-seeking-and-lifetime-smoking-among-high-school-students
#8
Sunhee Park, Junghee Kim, Heejin Hwang
BACKGROUND: Despite the greater risk of lifetime smoking among high sensation seekers, it is difficult to change a sensation seeking tendency through interventions. Therefore, it is important to identify a modifiable factor mediating the link between these two conditions in order to weaken or disconnect the association. OBJECTIVES: Based on the literature, deviant peers may play a pivotal role in explaining this association. Thus, we aimed to investigate the mediating effect of deviant peers on the association between sensation seeking and lifetime smoking among Korean adolescents...
December 1, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29190156/medication-assisted-treatment-for-youth-with-opioid-use-disorder-current-dilemmas-and-remaining-questions
#9
Derek C Chang, Jan Klimas, Evan Wood, Nadia Fairbairn
The prevalence of risky opioid use, opioid use disorder, and related harms continue to rise among youth (adolescents and young adults age 15-25) in North America. With an increasing number of opioid overdoses, there remain significant barriers to care for youth with opioid use disorder, and there is an urgent need to expand evidence-based care for treatment of opioid use disorder among this population. Based on the extensive literature on treatment of opioid use disorder among adults, medicated-assisted treatment is likely to be an important or even essential component of treatment of opioid use disorder for most youth...
November 30, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29095057/high-inpatient-utilization-among-veterans-health-administration-patients-with-substance-use-disorders-and-co-occurring-mental-health-conditions
#10
Janelle M Painter, Carol A Malte, Anna D Rubinsky, Timothy R Campellone, Amanda K Gilmore, John S Baer, Eric J Hawkins
BACKGROUND: Substance-use disorders (SUDs) are common and costly conditions. Understanding high inpatient utilization (HIU) among patients with SUD can inform the development of treatment approaches designed to reduce healthcare expenditures and improve service quality. OBJECTIVES: To examine the prevalence, type, and predictors of HIU among patients with SUD and co-occurring mental health conditions. METHODS: Service utilization and demographic and clinical variables were extracted from a national sample of Veterans Health Administration (VA) patients with SUD-only [n = 148,960 (98...
November 2, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29095046/molecular-spectroscopic-studies-examining-the-interactions-between-phenobarbital-and-human-serum-albumin-in-alcohol-consumption
#11
Sheng-Feng Cui, Wei Li, Cheng-He Zhou
BACKGROUND: Alcohol dependence is associated with a wide range of serious mental, physical, and social consequences and is one of the most common chronic diseases worldwide. Barbiturates, which are a first-line treatment in the clinic for alcohol withdrawal, may result in combined barbiturate and alcohol use. Their co-use abuse may promote synergistic effects between barbiturates and alcohol in vivo. OBJECTIVE: To investigate the effects of different alcohol concentrations on the synergistic effects of phenobarbital and alcohol...
November 2, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29144768/editorial-board-eov
#12
(no author information available yet)
No abstract text is available yet for this article.
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28662359/distinctions-between-seeking-and-non-seeking-treatment-research-participants-implications-for-clinical-trials-effectiveness
#13
Laura Acion, Janet Zwick, L Paloma Rojas Saunero, Stephan Arndt
No abstract text is available yet for this article.
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28662343/effect-of-chronic-%C3%AE-hydroxybutyrate-ghb-administration-on-ghb-toxicokinetics-and-ghb-induced-respiratory-depression
#14
Bridget L Morse, Gurkishan S Chadha, Melanie A Felmlee, Kristin E Follman, Marilyn E Morris
BACKGROUND: γ-hydroxybutyrate (GHB) has a high potential for illicit use; overdose of this compound results in sedation, respiratory depression and death. Tolerance to the hypnotic/sedative and electroencephalogram effects of GHB occurs with chronic GHB administration; however, tolerance to respiratory depression has not been evaluated. GHB toxicodynamic effects are mediated predominantly by GABAB receptors. Chronic treatment may affect monocarboxylate transporters (MCTs) and alter the absorption, renal clearance and brain uptake of GHB...
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28650668/categorization-of-psychoactive-substances-into-hard-drugs-and-soft-drugs-a-critical-review-of-terminology-used-in-current-scientific-literature
#15
Peter Janik, Michaela Kosticova, Jan Pecenak, Michal Turcek
BACKGROUND: Precise terminology and definitions are important components of scientific language. Although the terms "hard drugs" and "soft drugs" are used widely by professionals, neither the International Classification of Diseases nor the Diagnostic and Statistical Manual classify psychoactive substances into the categories "hard" and "soft." OBJECTIVES: To analyze the occurrence of the terms "hard drugs" and "soft drugs" in recent scientific literature and to establish the degree of consensus in labeling psychoactive substances as "hard" or "soft...
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28635349/the-association-between-alcohol-use-trajectories-from-adolescence-to-adulthood-and-cannabis-use-disorder-in-adulthood-a-22-year-longitudinal-study
#16
Jung Yeon Lee, Judith S Brook, Mario De La Rosa, Youngjin Kim, David W Brook
BACKGROUND: Due to the increasing prevalence of cannabis use disorder (CUD), the impact of cannabis use on public health may be significant. OBJECTIVE: The present study seeks the possible precursors (e.g., alcohol use) of CUD in order to minimize the potential negative consequences of CUD such as impaired coordination and performance. METHOD: The Harlem Longitudinal Development Study included 674 participants (53% African Americans, 47% Puerto Ricans), with 60% females (n=405) from a six wave survey...
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28635346/effect-of-drug-related-cues-on-response-inhibition-through-abstinence-a-pilot-study-in-male-heroin-abstainers
#17
Bobo Su, Ling Yang, Grace Y Wang, Sha Wang, Shaomei Li, Hua Cao, Yan Zhang
BACKGROUND: Chronic heroin use can cause a deficit of inhibitory function, leading to a loss of control over drug use. Exposure to drug-related cues is considered as one of the contributing factors. However, it is unclear whether there are dynamic changes on the effect of drug-related cues on response inhibition following prolonged abstinence. OBJECTIVE: The present study investigated the effect of drug-related cues on response inhibition in heroin abstainers at different abstinent phases...
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28635343/primary-psychopathy-and-alcohol-pathology-in-college-students-the-role-of-protective-behavioral-strategies
#18
Matthew P Kramer, Brittany L Stevenson, Robert D Dvorak
OVERVIEW: Though not an official diagnosis, psychopathy has become an important area of research due to the litany of deleterious outcomes associated with this aspect of temperament. Psychopathy is composed of primary and secondary traits. Research consistently links psychopathy to alcohol pathology, though often only via secondary traits which are comprised of intractable aspects of behavior (e.g., poor impulse control). In contrast, primary psychopathy is comprised of behaviors that can be learned and thus may be more malleable (i...
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28557531/importance-of-short-term-continuing-care-plan-adherence-on-long-term-outcomes-among-patients-discharged-from-residential-substance-use-treatment
#19
Steven L Proctor, Jaclyn L Wainwright, Philip L Herschman
BACKGROUND: Patients adherent to their recommended treatment regimen demonstrate favorable outcomes. However, it is unclear whether there are specific short-term continuing care performance variables indicative of better long-term prognosis. OBJECTIVE: This study determined the impact of attendance at an outpatient appointment within 7 days post-discharge from residential treatment on 12-month outcomes. METHOD: Data were abstracted from electronic medical records for 275 patients (58...
November 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28510498/deficits-in-go-no-go-task-performance-in-male-undergraduate-high-risk-alcohol-users-are-driven-by-speeded-responding-to-go-stimuli
#20
Xin Zhao, Wang Qian, Lily Fu, Joseph H R Maes
BACKGROUND: Response disinhibition plays an important role in addictive behaviors. However, results of studies on the performance on response inhibition tasks of individuals evidencing potentially problematic levels of alcohol drinking are mixed. OBJECTIVES: We assessed conditions under which persons with a relatively high risk of alcohol dependence show inhibition deficits in such tasks and investigated the nature of those deficits. METHODS: Fifty-eight male undergraduate students, 27 of which were high-risk drinkers according to the Alcohol Use Disorders Identification Test, performed a go/no-go inhibition task with differing percentages of no-go trials (50% vs...
November 2017: American Journal of Drug and Alcohol Abuse
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