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American Journal of Drug and Alcohol Abuse

Huixi Dong, Cheng Yang, Yidong Shen, Liang Liu, Mengqi Liu, Wei Hao
BACKGROUND: Repeated and extensive methamphetamine or ketamine use may cause psychotic symptoms. Whether the chronic and combined use of these substances has a greater psychotic effect is still unknown. OBJECTIVES: To examine the effect of different levels of ketamine use on psychotic disorders and symptoms in male methamphetamine-dependent subjects. METHODS: A cross-sectional, structured, and clinical interview method was used to examine the differences in DSM-IV-TR Axis I psychotic disorders and symptoms among methamphetamine-dependent subjects in three categories: 205 with no ketamine use, 38 with occasional ketamine use, and 72 with ketamine abuse or dependence from compulsory rehabilitation centers...
January 14, 2019: American Journal of Drug and Alcohol Abuse
Jesús Gómez-Bujedo, Sara Domínguez-Salas, Pedro Juan Pérez-Moreno, Enrique Moraleda-Barreno, Oscar M Lozano
BACKGROUND: Interpretation bias tasks such as word association tests have shown a moderate relation with substance use, but most studies have been conducted in nonclinical samples and these tasks are difficult to rate. OBJECTIVES: To provide: (1) reliability evidence of the Word Association Task for Drug Use Disorder (WAT-DUD), a novel and easy-to-rate instrument for measuring interpretation bias and (2) validity evidence based on the relationship between the WAT-DUD and variables associated with patterns of drug use and treatment outcomes...
January 14, 2019: American Journal of Drug and Alcohol Abuse
Canan Beate Schüller, Jens Kuhn, Frank Jessen, Xiaochen Hu
BACKGROUND: Delay discounting (DD) describes the phenomenon of devaluing future rewards in favor of immediate rewards. Increased DD is a key behavioral marker of addiction, and has been suggested as a target for interventions to alleviate addiction symptoms (e.g., preference for immediate drug use over larger-and-later rewards, and relapses) in patients with substance use disorders (SUD). OBJECTIVES: Performed a meta-analysis on neuroimaging results of DD regarding specific contrasts in healthy participants...
January 11, 2019: American Journal of Drug and Alcohol Abuse
Mitra-Sadat Sadat-Shirazi, Nima Babhadi-Ashar, Solmaz Khalifeh, Sarah Mahboubi, Hamid Ahmadian-Moghaddam, Mohammad-Reza Zarrindast
BACKGROUND: Besides the analgesic effect of tramadol, prolonged exposure to tramadol can induce adaptive changes thereby leading to dependence and tolerance. Tramadol induces its effect via µ-opioid receptor (MOR). However, tramadol has other targets such as serotonin and epinephrine transporters. OBJECTIVE: CREB and ΔFosB are transcriptional factors, which are involved in the behavioral abnormalities underlying drug abuse. In this study, the effects of acute and chronic tramadol treatments on MOR, ΔFosB, and CREB levels were studied...
January 11, 2019: American Journal of Drug and Alcohol Abuse
Devin E Banks, Alexandra R Hershberger, Taylor Pemberton, Richelle L Clifton, Matthew C Aalsma, Tamika C B Zapolski
BACKGROUND: Adolescent cannabis use is associated with increased risk for psychological problems, with evidence for more severe problems among youth who use cannabis in combination with other substances (i.e., polysubstance use). Juvenile offenders engage in both cannabis use and polysubstance use at higher rates than the general adolescent population. Yet, limited research has examined the relationship between cannabis poly-use (e.g., cannabis and alcohol use) and functional or psychological problems among juvenile offenders...
January 8, 2019: American Journal of Drug and Alcohol Abuse
Séverine Lannoy, Valérie Dormal, Joël Billieux, Pierre Maurage
BACKGROUND: Binge drinking, characterized by alternations between intense alcohol intakes and abstinence periods, is the most frequent alcohol-consumption pattern among adolescents and is associated with cognitive impairments. OBJECTIVES: It appears crucial to disentangle the psychological factors involved in the emergence of binge drinking in adolescence, and centrally the role played by drinking motives, which are related to binge drinking. METHODS: This longitudinal study explored the role of drinking motives (i...
January 2, 2019: American Journal of Drug and Alcohol Abuse
Joseph J Palamar, Alberto Salomone, Rachele Bigiarini, Marco Vincenti, Patricia Acosta, Babak Tofighi
BACKGROUND: Deaths from fentanyl exposure continue to increase in the US. Fentanyl test strips are now available to test urine for presence of fentanyl, but additional testing methods are needed to determine past exposure and to determine exposure to specific analogs. OBJECTIVES: To investigate exposure to such analogs through hair testing. METHODS: Forty individuals in inpatient detoxification (7.5% female) reporting past-month heroin use were surveyed and provided a hair sample to be tested at a later date...
January 2, 2019: American Journal of Drug and Alcohol Abuse
Montgomry L Burgoon, Thomas Albani, Brittney Keller-Hamilton, Bo Lu, Megan E Roberts, Peter F Craigmile, Christopher Browning, Wenna Xi, Amy K Ferketich
BACKGROUND: The tobacco industry spends billions on retail marketing and such marketing is associated with tobacco use. Previous research has not examined actual and potential exposures that adolescents have on a daily basis. OBJECTIVE: The objective of this study was to determine whether both self-reported and geographically estimated tobacco retailer exposures differ by participant or neighborhood characteristics among urban and rural adolescents. METHODS: The data for this study were part of a cohort study of 1220 adolescent males residing in urban and rural (Appalachian) regions in Ohio...
January 2, 2019: American Journal of Drug and Alcohol Abuse
Andrew C Naglich, E Sherwood Brown, Bryon Adinoff
BACKGROUND: Bupropion is a substituted cathinone compound widely used as a first line or add-on treatment for depression, smoking cessation, and more recently in combination with naltrexone for weight loss. As abuse of synthetic cathinone compounds has received more attention in recent years, concern about the misuse potential of bupropion has grown as well. OBJECTIVES: We review bupropion pharmacology and assessments of misuse potential including preclinical evidence, human studies, and post-marketing surveillance of bupropion misuse...
January 2, 2019: American Journal of Drug and Alcohol Abuse
S Callinan, G Rankin, R Room, O Stanesby, G Rao, O Waleewong, T K Greenfield, A Hope, A-M Laslett
BACKGROUND: Partners of heavy drinking individuals can be detrimentally affected as a result of their partner's drinking. OBJECTIVES: The aim of this study was to identify the proportion of heterosexual intimate partner relationships with a heavy drinking male that resulted in reported alcohol-related harm and to investigate the impact of this on well-being in 9 countries. METHODS: This study used survey data from the Gender and Alcohol's Harm to Others (GENAHTO) Project on Alcohol's Harm to Others in 9 countries (10,613 female respondents, 7,091 with intimate live-in partners)...
November 29, 2018: American Journal of Drug and Alcohol Abuse
Mukesh Maithani, Harpreet Grover, Richa Raturi, Vikas Gupta, Parveen Bansal
BACKGROUND: A large part of the population of India prefers the traditional medicine (ayurvedic formulations) for primary health care. However, the effective quality control of herbal medicine is still a big challenge. Numerous reports indicate noncompliance with Compromised Good Manufacturing Practice (GMP) guidelines by the manufacturers which may lead to adverse drug reactions or toxic effects. Asava and arishta are the classical herbal dosage forms wherein fermentation occurs during production leading to the generation of ethanol...
November 14, 2018: American Journal of Drug and Alcohol Abuse
Jani Kajanoja, Noora M Scheinin, Max Karukivi, Linnea Karlsson, Hasse Karlsson
BACKGROUND: A high prevalence of alexithymia has been consistently reported in alcohol- and drug-dependent populations. However, less is known about the role of alexithymia, and its individual dimensions on substance use in healthier populations. OBJECTIVES: To examine how different alexithymia dimensions associate with substance use, while controlling for confounding factors. METHODS: In the FinnBrain Birth Cohort Study, we analyzed a sample of 994 men...
November 14, 2018: American Journal of Drug and Alcohol Abuse
Alexandre Lemyre, Audrey Gauthier-Légaré, Richard E Bélanger
Researchers have increasingly studied shyness, social anxiety, and social anxiety disorder (SAD) as potential precursors of substance use. OBJECTIVES: The objective of this study was to review the relationships between these variables and tobacco use, alcohol use, and cannabis/drug use in normative adolescent populations and the extent to which these associations differ by gender. METHODS: A systematic search in PsycINFO and PubMed was conducted, reference screening was performed, and five experts were consulted...
November 13, 2018: American Journal of Drug and Alcohol Abuse
Lara A Ray, Spencer Bujarski, Erica Grodin, Emily Hartwell, ReJoyce Green, Alexandra Venegas, Aaron C Lim, Artha Gillis, Karen Miotto
BACKGROUND: Alcohol use disorder (AUD) and its associated consequences remain significant public health concerns. Given that AUD represents a spectrum of severity, treatment options represent a continuum of care, ranging from single-session brief interventions to more intensive, prolonged, and specialized treatment modalities. OBJECTIVE: This qualitative literature review seeks to describe the best practices for AUD by placing a particular emphasis on identifying those practices which have received the most empirical support...
October 29, 2018: American Journal of Drug and Alcohol Abuse
Scott C Wollman, Alexander O Hauson, Matthew G Hall, Eric J Connors, Kenneth E Allen, Mark J Stern, Rick A Stephan, Christine L Kimmel, Sharis Sarkissians, Brianna D Barlet, Christopher Flora-Tostado
BACKGROUND: Research has demonstrated that patients with opioid use disorders (OUD; including both opioid abuse and/or dependence) have poorer neuropsychological functioning compared to healthy controls; however, the pattern and robustness of the findings remain unknown. OBJECTIVES: This study meta-analyzed the results from previous research examining the neuropsychological deficits associated with opioids across 14 neurocognitive domains. METHOD: Articles comparing patients with OUD to healthy controls were selected based on detailed inclusion/exclusion criteria and variables of interest were coded...
October 25, 2018: American Journal of Drug and Alcohol Abuse
Grace L Reynolds, Dennis G Fisher
BACKGROUND: Alcohol and drug use by women is related to high-risk sexual practices and protective behaviors. OBJECTIVES: To determine sexual risk and protective behaviors using information about women's drug use immediately before or during sex. METHODS: Latent class analysis using PROC LCA in SAS software was used to determine classes of women using both past 30-day drug use and before or during sex. Participants were recruited from a community-based research site located in a low socio-economic area of Los Angeles County and completed the Risk Behavior Assessment, which elicits information on drug and sex risk behaviors...
October 25, 2018: American Journal of Drug and Alcohol Abuse
Joseph J Palamar
Surveys are the leading method of gathering data on prevalence and correlates of prescription opioid misuse. As the opioid crisis continues in the United States, reliable data on misuse have become increasingly important as under- and overreporting is common. This perspective discusses six potential barriers to researchers accurately assessing opioid misuse on surveys. These barriers include lack of respondent drug knowledge, researchers not properly defining opioids for respondents, querying overall opioid misuse rather than misuse of specific opioids, varying terminology (e...
September 19, 2018: American Journal of Drug and Alcohol Abuse
Chris Patterson, Lee Hogan, Miles Cox
BACKGROUND: There are two main categories of retrospective self-report alcohol consumption measures: summary and daily drinking. Time-efficient summary measures have been criticized for being less able to capture sporadic and unpatterned drinking. A novel retrospective summary measure, the Typical and Atypical Drinking Diary (TADD), may produce more precise estimates of alcohol consumption than the gold-standard daily measure, the Timeline Followback (TLFB). OBJECTIVE: To establish how accurately the TADD and TLFB retrospectively capture alcohol consumption compared to the Daily Drinking Diary (DDD) method...
September 19, 2018: American Journal of Drug and Alcohol Abuse
Marco Cavicchioli, Mariagrazia Movalli, Cesare Maffei
BACKGROUND: Theoretical frameworks postulate that mindfulness represents a relevant therapeutic process in substance use disorders (SUDs), especially in treating difficulties with emotion regulation (DER). Nonetheless, it remains unclear how mindfulness dimensions, particularly self-regulation of attention and acceptance attitudes, are implicated in the well-validated relationship between DER and SUDs. It is also uncertain whether mindfulness is considered a common protective factor for SUDs...
September 14, 2018: American Journal of Drug and Alcohol Abuse
Benjamin R Castine, Natalia Albein-Urios, Oscar Lozano-Rojas, Jose M Martinez-Gonzalez, Jakob Hohwy, Antonio Verdejo-Garcia
BACKGROUND: Individuals with cocaine use disorder (CUD) often display behaviours that are paradoxically misaligned with their situation. Typical examples include poor treatment motivation and inconsistent self-reported craving. These behaviours may reflect impairments in the awareness of one's own behaviour. OBJECTIVES: We examined whether impaired self-awareness of addiction-related frontostriatal dysfunction (i.e., symptoms of apathy, disinhibition, and executive dysfunction) was associated with treatment motivation and craving...
September 5, 2018: American Journal of Drug and Alcohol Abuse
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