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American Journal of Drug and Alcohol Abuse

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https://www.readbyqxmd.com/read/28541119/treatment-of-opioid-use-disorder-with-ibogaine-detoxification-and-drug-use-outcomes
#1
Thomas Kingsley Brown, Kenneth Alper
BACKGROUND: Ibogaine is a monoterpene indole alkaloid used in medical and nonmedical settings for the treatment of opioid use disorder. Its mechanism of action is apparently novel. There are no published prospective studies of drug use outcomes with ibogaine. OBJECTIVES: To study outcomes following opioid detoxification with ibogaine. METHODS: In this observational study, 30 subjects with DSM-IV Opioid Dependence (25 males, 5 females) received a mean total dose of 1,540 ± 920 mg ibogaine HCl...
May 25, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28498718/effects-of-regular-cannabis-use-on-neurocognition-brain-structure-and-function-a-systematic-review-of-findings-in-adults
#2
Danilo A Nader, Zila M Sanchez
BACKGROUND: Cannabis is the most used illicit drug worldwide. The long-standing consequences for the central nervous system associated with frequent cannabis use have not been well delineated and should be determined. OBJECTIVE: To review recent studies on the effects of regular cannabis use regarding its effects on cognition, brain structure, and function in adults. METHODS: A systematic literature review was conducted by performing electronic searches in the PubMed, LILACS, and SciELO databases (2010-2016)...
May 12, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28485987/assessing-self-reported-use-of-new-psychoactive-substances-the-impact-of-gate-questions
#3
Joseph J Palamar, Patricia Acosta, Fermín Fernández Calderón, Scott Sherman, Charles M Cleland
BACKGROUND: New psychoactive substances (NPS) continue to emerge; however, few surveys of substance use ask about NPS use. Research is needed to determine how to most effectively query use of NPS and other uncommon drugs. OBJECTIVE: To determine whether prevalence of self-reported lifetime and past-year use differs depending on whether or not queries about NPS use are preceded by "gate questions." Gate questions utilize skip-logic, such that only a "yes" response to the use of specific drug class is followed by more extensive queries of drug use in that drug class...
May 9, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28481655/young-adult-binge-drinkers-have-immunophenotypic-changes-in-peripheral-polymorphonuclear-cells-and-monocytes
#4
Adolfo Pérez-García, América Guadalupe Arroyo-Valerio, José Luis Zaldivar-Fujigaki, Mayra A Bustos-Esquivel, Alfonso Gastelum-Strozzi, Miguel A Padilla-Castañeda, Arturo Reding-Bernal, David Kershenobich, Joselín Hernández-Ruiz
BACKGROUND: High alcohol intake on weekends (binge drinking) is more frequent in young adults, who could undergo early liver damage. Alcohol-induced liver damage is characterized by polymorphonuclear cell (PMN) infiltration, which can be represented in the peripheral blood by altered trafficking and activation profiles. OBJECTIVE: To evaluate the PMN trafficking and activation immunophenotypic profiles in people with a binge drinking pattern. METHODS: People with binge drinking (n = 18, 8 females) or at low risk (n = 16, 13 females) based on their AUDIT and HEPCA scores were studied...
May 8, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28481633/the-best-of-both-worlds-avatar-assisted-therapy-offers-the-benefits-of-therapist-assisted-and-internet-based-interventions
#5
Darla E Kendzor, Emily T Hébert
No abstract text is available yet for this article.
May 8, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28481624/older-adults-marijuana-use-injuries-and-emergency-department-visits
#6
Namkee G Choi, C Nathan Marti, Diana M DiNitto, Bryan Y Choi
BACKGROUND: Despite increasing marijuana use among older adults, little research has been done on marijuana's effects on their healthcare use. OBJECTIVES: To examine whether (1) marijuana use is associated with the likelihood of emergency department (ED) visits through increased injury risk, and (2) marijuana use patterns are associated with injury risk and ED visits among older adults. METHODS: Using the 2012-2013 National Epidemiologic Survey on Alcohol and Related Problems (N = 14,715 aged 50+; 6,379 men and 8,336 women), descriptive statistics were used to compare past-year marijuana users to nonusers on sociodemographic and physical/mental health characteristics...
May 8, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28471245/there-has-been-little-progress-in-implementing-comprehensive-alcohol-control-strategies-in-africa
#7
Nasheeta Peer
Alcohol is the most common substance of addiction and a threat not only to health but also to sustainable human development. Consequently, at least a 10% relative reduction in the harmful use of alcohol has been advocated by the World Health Organization (WHO). This perspective describes alcohol use in Africa, strategies to reduce harmful alcohol use, and the ability of African countries to meet this target. Although alcohol consumption in Africa was intermediate compared to other world regions, the total alcohol per capita among alcohol consumers was the second highest (19...
May 4, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28471244/aldh2-2-and-peer-drinking-in-east-asian-college-students
#8
Taryn O'Shea, Nathaniel Thomas, Bradley Todd Webb, Danielle M Dick, Kenneth S Kendler, Karen G Chartier
BACKGROUND: The ALDH2*2 allele (A-allele) at rs671 is more commonly carried by Asians and is associated with alcohol-related flushing, a strong adverse reaction to alcohol that is protective against drinking. Social factors, such as having friends who binge drink, also contribute to drinking in Asian youth. OBJECTIVES: This study examined the interplay between ALDH2*2, peer drinking, and alcohol consumption in college students. We hypothesized that the relationship between ALDH2*2 and standard grams of ethanol per month would vary based on the level of peer drinking...
May 4, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28448718/cannabis-use-by-women-during-pregnancy-does-not-influence-infant-dna-methylation-of-the-dopamine-receptor-drd4
#9
Peter D Fransquet, Delyse Hutchinson, Craig A Olsson, Steve Allsop, Elizabeth J Elliott, Lucinda Burns, Richard Mattick, Richard Saffery, Joanne Ryan
BACKGROUND: Maternal cannabis use in pregnancy is linked with long-term adverse behavioral outcomes in offspring. Epigenetic processes established in utero that affect dopaminergic (reward) signaling may mediate risks. Associations between cannabis use and offspring DNA methylation have not been investigated; however, maternal tobacco smoking in pregnancy is associated with distinct patterns of DNA methylation at birth and beyond. OBJECTIVES: To determine whether maternal cannabis use is associated with methylation of the dopamine receptor gene DRD4 promoter in infants...
April 27, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28426264/differences-between-treatment-seeking-and-non-treatment-seeking-participants-in-medication-studies-for-alcoholism-do-they-matter
#10
Lara A Ray, Spencer Bujarski, Megan M Yardley, Daniel J O Roche, Emily E Hartwell
BACKGROUND: Medication development for alcoholism typically includes experimental pharmacology studies with non-treatment-seeking individuals with alcohol use disorder (AUD) paving the way for randomized controlled trials in treatment-seekers with AUD. OBJECTIVES: The goal of this study is to provide a direct comparison between AUD treatment-seeking research participants and non-treatment-seeking participants on demographic and clinical variables and to test whether variables that differentiate the two groups are associated with clinical outcomes...
April 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28410003/smoking-cessation-treatment-in-substance-use-disorder-treatment-settings-an-emergency-too
#11
Alain Braillon
No abstract text is available yet for this article.
April 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28410002/comparing-behavioral-health-models-for-reducing-risky-drinking-among-older-male-veterans
#12
Nikki R Wooten, Abbas S Tavakoli, Marlene B Al-Barwani, Naomi A Thomas, Hrishikesh Chakraborty, Anna M Scheyett, Kelly M Kaminski, Alyssia C Woods, Sue E Levkoff
BACKGROUND: Screening older veterans in Veterans Affairs Medical Center (VAMC) primary care clinics for risky drinking facilitates early identification and referral to treatment. OBJECTIVE: This study compared two behavioral health models, integrated care (a standardized brief alcohol intervention co-located in primary care clinics) and enhanced referral care (referral to specialty mental health or substance abuse clinics), for reducing risky drinking among older male VAMC primary care patients...
April 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28402753/author-s-response-smoking-cessation-treatment-in-substance-use-disorder-settings
#13
Hannah K Knudsen
No abstract text is available yet for this article.
April 12, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28402711/prevalence-and-incidence-of-drug-use-among-college-students-an-8-year-longitudinal-analysis
#14
Amelia M Arria, Kimberly M Caldeira, Hannah K Allen, Brittany A Bugbee, Kathryn B Vincent, Kevin E O'Grady
BACKGROUND: Drug use among college students is associated with adverse academic and health outcomes and risks to personal safety. OBJECTIVES: This study utilized data from a longitudinal study to estimate annual prevalence, cumulative lifetime prevalence, and incidence of ten types of drug use during the eight years after college entry and the average age of onset of each drug used. METHODS: Participants (N = 1,253; 52% female) were young adults who were originally enrolled as first-time, first-year students at a university in the mid-Atlantic US...
April 12, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28402682/ibogaine-treatment-outcomes-for-opioid-dependence-from-a-twelve-month-follow-up-observational-study
#15
Geoffrey E Noller, Chris M Frampton, Berra Yazar-Klosinski
BACKGROUND: The psychoactive indole alkaloid ibogaine has been associated with encouraging treatment outcomes for opioid dependence. The legal status of ibogaine in New Zealand provides a unique opportunity to evaluate durability of treatment outcomes. OBJECTIVE: To examine longitudinal treatment effects over a 12-month period among individuals receiving legal ibogaine treatment for opioid dependence. METHOD: This observational study measured addiction severity as the primary outcome in 14 participants (50% female) over 12 months post-treatment using the Addiction Severity Index-Lite (ASI-Lite) following a single ibogaine treatment by either of two treatment providers...
April 12, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28387530/combining-medically-assisted-treatment-and-twelve-step-programming-a-perspective-and-review
#16
Marc Galanter
BACKGROUND: People with severe substance use disorders require long-term rehabilitative care after the initial treatment. There is, however, a deficit in the availability of such care. This may be due both to inadequate medical coverage and insufficient use of community-based Twelve-Step programs in many treatment facilities. In order to address this deficit, rehabilitative care for severe substance use disorders could be promoted through collaboration between practitioners of medically assisted treatment, employing medications, and Twelve-Step-oriented practitioners...
April 7, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28375656/evidence-based-treatment-and-supervision-practices-for-co-occurring-mental-and-substance-use-disorders-in-the-criminal-justice-system
#17
Roger H Peters, M Scott Young, Elizabeth C Rojas, Claire M Gorey
BACKGROUND: Over seven million persons in the United States are supervised by the criminal justice system, including many who have co-occurring mental and substance use disorders (CODs). This population is at high risk for recidivism and presents numerous challenges to those working in the justice system. OBJECTIVES: To provide a contemporary review of the existing research and examine key issues and evidence-based treatment and supervision practices related to CODs in the justice system...
April 4, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28345966/the-importance-of-standardization-of-stimuli-for-functional-mri-tasks-to-evaluate-substance-use-disorder-pathology
#18
Claire E Wilcox, Eric D Claus
No abstract text is available yet for this article.
March 27, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28301250/naltrexone-in-the-treatment-of-binge-eating-disorder-in-a-patient-with-severe-alcohol-use-disorder-a-case-report
#19
Arnaud Leroy, Louise Carton, Harry Gomajee, Regis Bordet, Olivier Cottencin
No abstract text is available yet for this article.
March 16, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28301219/management-of-comorbid-bipolar-disorder-and-substance-use-disorders
#20
Ihsan M Salloum, Edson Sherwood Brown
BACKGROUND: The comorbidity of substance use disorders (SUDs) in bipolar disorder is among the highest in psychiatric disorders. Evidence-based controlled psychosocial or pharmacological interventions trials, which may guide treatment decisions, have not been systematically reviewed. OBJECTIVE: To present a narrative review of the public health and clinical significance of this condition, including diagnostic and treatment implications, and to evaluate controlled trials conducted to date...
March 16, 2017: American Journal of Drug and Alcohol Abuse
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