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American Journal of Drug and Alcohol Abuse

Patricia A Cavazos-Rehg, Melissa J Krauss, Shaina J Sowles, Glennon M Floyd, Elizabeth S Cahn, Veronica L Chaitan, Marisel Ponton
BACKGROUND: The US has seen an increase in the popularity of highly concentrated forms of cannabis (hereafter concentrates) and too little is known about the potential risks associated with their use. OBJECTIVES: The present study aims to better understand the patterns and outcomes of concentrates use through the perspectives of young adult users. METHODS: Participants (N = 234, 27.9% female) aged 18-35 years were recruited using SurveyMonkey Audience® and had ingested concentrates at least once in the past 6 months...
March 7, 2018: American Journal of Drug and Alcohol Abuse
Cory A Crane
BACKGROUND: Efforts designed to investigate the effects of recent alcohol use on the perception of intimate partner aggression have been stultified by significant financial and logistical barriers that warrant the development of supplemental research methods that may result in more prolific investigation of the phenomenon. OBJECTIVES: The current study explored the viability of using online crowdsourcing to assess the effects of recent alcohol use on the perception of partner aggression...
March 7, 2018: American Journal of Drug and Alcohol Abuse
Bin Yu, Xinguang Chen, Yan Wang
BACKGROUND: Marijuana and tobacco are considered two closely related substances. It is of great significance to understand the mutual impact of marijuana and cigarette use when more states in the US have legalized marijuana use. OBJECTIVE: This study aims to investigate the transitions between marijuana and cigarette use among adolescents and emerging adults. METHOD: Guided by the probabilistic discrete events systems (PDES) theory, a five-stage model with 21 transition paths was constructed to quantify dynamic transitions between marijuana and cigarette use...
March 7, 2018: American Journal of Drug and Alcohol Abuse
Rachel L Tomko, Kevin M Gray, Stephanie R Oppenheimer, Amy E Wahlquist, Erin A McClure
BACKGROUND: The use of ambulatory assessment to study behavior and physiology in daily life is becoming more common, yet barriers to implementation remain. Limitations in budget, time, and expertise may inhibit development or purchase of dedicated ambulatory assessment software. Research Electronic Data Capture (REDCap) is widely used worldwide, offering a cost-effective and accessible option for implementing research studies. OBJECTIVES: To present a step-by-step guideline on how to implement ambulatory assessment using REDCap and provide preliminary evidence of feasibility...
March 7, 2018: American Journal of Drug and Alcohol Abuse
Jennifer M Reingle Gonzalez, Scott T Walters, Jennifer Lerch, Faye S Taxman
BACKGROUND: Although many formal and informal substance use treatment programs were originally designed for men, no studies have investigated how gender affects the use of substance use treatment modalities, and how gender differences in treatment utilization impact substance use in the unique probation context. OBJECTIVE: To describe gender differences in use and effectiveness of substance use treatment modalities (formal and informal) among probationers. METHODS: Longitudinal data were obtained from 335 individuals (93 women) who participated in the Motivational Assessment Program to Initiate Treatment (MAPIT) study...
February 16, 2018: American Journal of Drug and Alcohol Abuse
Julia D Buckner, Emily R Jeffries, Ross D Crosby, Michael J Zvolensky, Courtenay E Cavanaugh, Stephen A Wonderlich
BACKGROUND: Accumulating evidence indicates a link between post-traumatic stress disorder (PTSD) and cannabis use and suggests that this link may vary as a function of the PTSD symptom cluster type. Consistent with negative reinforcement models of substance use, individuals with elevated Cluster D (Hyperarousal) symptoms may be more likely to use cannabis in response to elevated state anxiety and experience decreases in state anxiety after using cannabis. OBJECTIVES: We aimed to test hypotheses that the interaction of Cluster D and state anxiety would be related to subsequent cannabis use and that those with elevated Cluster D symptoms who used cannabis would report the greatest decreases in state anxiety...
February 14, 2018: American Journal of Drug and Alcohol Abuse
Rubén Rodríguez-Cano, Daniel J Paulus, Michael J Zvolensky, Ana López-Durán, Carmela Martínez-Vispo, Elisardo Becoña
BACKGROUND: Depressive symptoms and craving are related to smoking maintenance; however, little is known about the association between trajectories of depressive symptoms and smoking craving after quitting. OBJECTIVES: We examined if depressive symptom change relates to change in craving following smoking cessation treatment. METHODS: Participants were 362 (64.1% female; 35.9% male) adult treatment seeking smokers who quit smoking after treatment...
February 8, 2018: American Journal of Drug and Alcohol Abuse
Daniel P Notzon, Meredith A Kelly, C Jean Choi, Martina Pavlicova, Amy L Mahony, Daniel J Brooks, John J Mariani, Frances R Levin
BACKGROUND: There are no FDA-approved pharmacotherapies for cannabis use disorders (CUD), despite the evaluation of numerous medications. Notably, chronic dosing of oral naltrexone decreases self-administration of cannabis in human laboratory studies. OBJECTIVES: To test the feasibility of long-acting injectable naltrexone for the treatment of CUD, while obtaining preliminary safety and efficacy data. METHODS: Twelve adult participants (seven male) meeting DSM-IV-TR criteria for cannabis dependence enrolled into an 8-week, open-label pilot study conducted at an academic treatment research clinic...
February 8, 2018: American Journal of Drug and Alcohol Abuse
Richard N Rosenthal
No abstract text is available yet for this article.
February 2, 2018: American Journal of Drug and Alcohol Abuse
Sean X Luo, Melanie Wall, Lirio Covey, Mei-Chen Hu, Jennifer M Scodes, Frances R Levin, Edward V Nunes, Theresa Winhusen
BACKGROUND: A double blind, placebo-controlled randomized trial (NCT00253747) evaluating osmotic-release oral system methylphenidate (OROS-MPH) for smoking-cessation revealed a significant interaction effect in which participants with higher baseline ADHD severity had better abstinence outcomes with OROS-MPH while participants with lower baseline ADHD severity had worse outcomes. OBJECTIVES: This current report examines secondary outcomes that might bear on the mechanism for this differential treatment effect...
January 25, 2018: American Journal of Drug and Alcohol Abuse
Anna Pagano, Noah Gubner, Thao Le, Joseph Guydish
BACKGROUND: Differences in tobacco use behaviors have been identified between Latinos and non-Latino whites in the general US population. Little is known about cigarette smoking and quitting behaviors of Latinos in treatment for substance use disorders (SUDs), who represent two major tobacco-vulnerable groups. OBJECTIVES: To compare, in a national sample of persons enrolled in SUD treatment, demographic, drug use, and smoking and quitting prevalence and behaviors between Latinos and non-Latino whites...
January 15, 2018: American Journal of Drug and Alcohol Abuse
Richard C Crist, James Li, Glenn A Doyle, Alex Gilbert, Bryan M Dechairo, Wade H Berrettini
BACKGROUND: Currently, no pharmacogenetic tests for selecting an opioid-dependence pharmacotherapy have been approved by the US Food and Drug Administration. OBJECTIVES: Determine the effects of variants in 11 genes on dropout rate and dose in patients receiving methadone or buprenorphine/naloxone ( Identifier: NCT00315341). METHODS: Variants in six pharmacokinetic genes (CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4) and five pharmacodynamic genes (HTR2A, OPRM1, ADRA2A, COMT, SLC6A4) were genotyped in samples from a 24-week, randomized, open-label trial of methadone and buprenorphine/naloxone for the treatment of opioid dependence (n = 764; 68...
January 15, 2018: American Journal of Drug and Alcohol Abuse
Diane Santa Maria, Nikhil Padhye, Yijiong Yang, Kathryn Gallardo, Glenn-Milo Santos, Julie Jung, Michael Businelle
BACKGROUND: Alcohol and drug use is associated with significant morbidity and mortality and is highly prevalent among homeless youth. Ecological Momentary Assessments (EMA) have been used to examine the effect of urges on drug use, though not among homeless youth. OBJECTIVES: We assessed the patterns of drug use and the correlation between real-time contextual factors and drug use using EMA collected daily. We identified predictors of drug use among a sample of homeless youth 18-25 years old in Houston, Texas...
December 29, 2017: American Journal of Drug and Alcohol Abuse
Melvin D Livingston, Brad Cannell, Keith Muller, Kelli A Komro
BACKGROUND: Despite concerns over measurement error, self-report continues to be the most common measure of adolescent alcohol use used by researchers. Objective measures of adolescent alcohol use continue to advance; however, they tend to be cost prohibitive for larger studies. By combining appropriate statistical techniques and validation subsamples, the benefits of objective alcohol measures can be made more accessible to a greater number of researchers. OBJECTIVES: To compare three easily implemented methods to correct for measurement error when objective measures of alcohol use are available for a subsample of participants, regression calibration, multiple imputation for measurement error (MIME), and probabilistic sensitivity analysis (PSA), and provide guidance regarding the use of each method in scenarios likely to occur in practice...
2018: American Journal of Drug and Alcohol Abuse
Sean M Robinson, Bryon Adinoff
No abstract text is available yet for this article.
2018: American Journal of Drug and Alcohol Abuse
Deborah C Mash
No abstract text is available yet for this article.
2018: American Journal of Drug and Alcohol Abuse
Derek C Chang, Jan Klimas, Evan Wood, Nadia Fairbairn
The prevalence of risky opioid use, opioid use disorder, and related harms continue to rise among youth (adolescents and young adults age 15-25) in North America. With an increasing number of opioid overdoses, there remain significant barriers to care for youth with opioid use disorder, and there is an urgent need to expand evidence-based care for treatment of opioid use disorder among this population. Based on the extensive literature on treatment of opioid use disorder among adults, medicated-assisted treatment is likely to be an important or even essential component of treatment of opioid use disorder for most youth...
2018: American Journal of Drug and Alcohol Abuse
Jon M Houck, Sarah W Feldstein Ewing
BACKGROUND: Brief addiction treatments including motivational interviewing (MI) have shown promise with adolescents, but the factors that influence treatment efficacy in this population remain unknown. One candidate is working memory, the ability to hold a fact or thought in mind. This is relevant, as in therapy, a client must maintain and manipulate ideas while working with a clinician. Working memory depends upon brain structures and functions that change markedly during neurodevelopment and that can be negatively impacted by substance use...
2018: American Journal of Drug and Alcohol Abuse
Michelle J Zaso, Jessica M Desalu, Jueun Kim, Kavita Suryadevara, John M Belote, Aesoon Park
BACKGROUND: Black young adults have lower rates of alcohol use than other racial groups. Genetic factors may protect against drinking. Specifically, the ADH1B*3 allele is present almost exclusively in Black populations and has been protective against alcohol use and alcohol use disorder. The protective effects of the ADH1B*3 allele, however, may differ as a function of alcohol-promoting cognitions. OBJECTIVES: The current study examined whether ADH1B*3 moderated relations of drinking motives with alcohol consumption among Black college drinkers...
2018: American Journal of Drug and Alcohol Abuse
Megan E Patrick, Deborah D Kloska, Yvonne M Terry-McElrath, Christine M Lee, Patrick M O'Malley, Lloyd D Johnston
BACKGROUND: Alcohol and marijuana are the most commonly used substances among adolescents but little is known about patterns of co-use. OBJECTIVES: This study examined patterns of concurrent (not overlapping) and simultaneous (overlapping) use of alcohol and marijuana among adolescents. METHODS: Data from US-national samples of 12th graders (N = 84,805, 48.4% female) who participated in the Monitoring the Future study from 1976 to 2016 and who used alcohol and/or marijuana in the past 12 months were used to identify latent classes of alcohol use, marijuana use, and simultaneous alcohol and marijuana (SAM) use...
December 20, 2017: American Journal of Drug and Alcohol Abuse
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