journal
MENU ▼
Read by QxMD icon Read
search

American Journal of Drug and Alcohol Abuse

journal
https://www.readbyqxmd.com/read/28165770/response-to-letter
#1
Bart Hammig, Page Daniel, Heather Blunt-Vinti
No abstract text is available yet for this article.
February 6, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28121474/elevated-levels-of-dna-methylation-at-the-oprm1-promoter-region-in-men-with-opioid-use-disorder
#2
Ghasem Ebrahimi, Gholamreza Asadikaram, Hamed Akbari, Mohammad Hadi Nematollahi, Moslem Abolhassani, Gholamabbas Shahabinejad, Leyla Khodadadnejad, Mohammad Hashemi
BACKGROUND: The mu-opioid receptor, encoded by mu-opioid receptor gene (OPRM1), has an important role in the development of addiction to opioids. Its aberrant reduction on the cell membrane is responsible, at least in part, for tolerance and physical dependence. OBJECTIVES: The present study was designed to identify the relationship between opium consumption and epigenetic mechanisms involved in opium addiction. METHODS: Genomic DNA was extracted from the peripheral blood of 66 men with opium use disorder and 57 healthy men as a control group...
January 25, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28075175/racial-group-categorization-in-minority-drug-use-studies
#3
Bin Yu
No abstract text is available yet for this article.
January 11, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28032813/effects-of-the-circle-of-life-hiv-prevention-program-on-marijuana-use-among-american-indian-middle-school-youths-a-group-randomized-trial-in-a-northern-plains-tribe
#4
Nancy L Asdigian, Nancy Rumbaugh Whitesell, Ellen M Keane, Alicia C Mousseau, Carol E Kaufman
BACKGROUND: Early substance use threatens many American Indian/Alaska Native (AI/AN) communities, as it is a risk factor for maladaptive use and adverse health outcomes. Marijuana is among the first substances used by AI/AN youth, and its use becomes widespread during adolescence. Interventions that delay or reduce marijuana use hold the promise of curbing substance disorders and other health risk disparities in AI/AN populations. OBJECTIVES: We evaluated the effectiveness of the Circle of Life (COL) program in reducing marijuana use among young AI adolescents...
December 29, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28032807/region-specific-expression-of-precursor-and-mature-brain-derived-neurotrophic-factors-after-chronic-alcohol-exposure
#5
Jin-Wei Yang, Wei Ma, Yan-Lei Yang, Xian-Bin Wang, Xing-Tong Li, Tong-Tong Wang, Xiang-Peng Wang, Wei Gao, Jun-Yan Li, Xin-Fu Zhou, Jian-Hui Guo, Li-Yan Li
BACKGROUND: Alcohol abuse is a serious health problem worldwide that causes a variety of physical and mental disorders. Research has shown that the brain-derived neurotrophic factor (BDNF) plays an important role in alcohol addiction. The BDNF precursor (proBDNF) exhibits different actions than BDNF through separate receptors and pathways in the central nervous system. However, the effects of proBDNF and BDNF in alcohol addiction are not fully known. OBJECTIVES: The objective was to identify the expression patterns and effects of proBDNF and BDNF after chronic alcohol exposure...
December 29, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28032801/blackouts-among-male-and-female-youth-seeking-emergency-department-care
#6
Diana M Voloshyna, Erin E Bonar, Rebecca M Cunningham, Mark A Ilgen, Frederic C Blow, Maureen A Walton
BACKGROUND: Alcohol-related blackouts are a common consequence of heavy drinking, and these blackouts pose risk for injury and other adverse health outcomes. OBJECTIVE: To examine the prevalence and correlates of blackouts among underage drinkers. METHODS: Youth (ages 14-20) presenting to a suburban Emergency Department (ED) completed screening surveys. Among those reporting past-year alcohol consumption, we examined past 3-month blackouts in relation to: background characteristics (e...
December 29, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28010130/treatment-of-alcohol-use-disorder-and-co-occurring-ptsd
#7
Mandrill Taylor, Ismene Petrakis, Elizabeth Ralevski
BACKGROUND: Alcohol use disorder (AUD) is a serious psychiatric disorder with medical, psychiatric, and social consequences. In individuals with comorbid post-traumatic stress disorder (PTSD), treatment outcomes are notably worse in comparison with treatment outcomes associated with either disorder occurring alone. There is a growing literature evaluating treatments, both pharmacotherapy and psychotherapy focused, in individuals with co-occurring AUD and PTSD. The main objective of this review was to evaluate pharmacotherapy and psychotherapy studies that were specifically designed to evaluate the treatment of individuals with comorbid AUD and PTSD...
December 23, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28010126/quantifying-impatience-using-models-of-delay-discounting-in-substance-use-disorders
#8
Suzanne H Mitchell
No abstract text is available yet for this article.
December 23, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27996310/severity-of-alcohol-dependence-is-negatively-related-to-hypothalamic-and-prefrontal-cortical-gray-matter-density-in-heavy-drinking-smokers
#9
Kyle Bullock, Anita Cservenka, Lara A Ray
BACKGROUND: While research has examined brain structure in individuals who use alcohol or nicotine, heavy drinking smokers comprise a unique subpopulation of substance users for whom less is known about the relationship between alcohol or nicotine use and structural brain abnormalities. OBJECTIVES: The present study examined gray matter morphometry in a sample of 39 heavy drinking smokers (24 males, 15 females) in relation to alcohol and nicotine dependence and quantity of use...
December 20, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27929684/acute-effects-of-snus-in-never-tobacco-users-a-pilot-study
#10
Jenny E Ozga, Nicholas J Felicione, Daniel Elswick, Melissa D Blank
BACKGROUND: Snus tobacco characteristics may attract non-tobacco users, including relatively low, but pharmacologically active, doses of nicotine. Lower nicotine doses may limit adverse drug effects while also producing a physiologically active response. OBJECTIVES: This pilot study is the first to profile the acute effects of snus on physiological and subjective assessments in a sample of never-tobacco users. METHODS: Eleven never-tobacco users (five women; <100 uses/lifetime) were recruited from the community via university-approved advertisements...
December 8, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27929672/long-term-consequences-of-adolescent-cannabis-use-examining-intermediary-processes
#11
Kerry M Green, Elaine E Doherty, Margaret E Ensminger
BACKGROUND: In the United States, perceptions of marijuana's acceptability are at an all-time high, risk perceptions among youth are low, and rates are rising among Black youth. Thus, it is imperative to increase the understanding of long-term effects of adolescent marijuana use and ways to mitigate adverse consequences. OBJECTIVES: To identify the midlife consequences of heavy adolescent marijuana use and the mechanisms driving effects among a Black, urban population...
December 8, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27893279/american-alcohol-photo-stimuli-aaps-a-standardized-set-of-alcohol-and-matched-non-alcohol-images
#12
Christopher S Stauffer, Lily Dobberteen, Joshua D Woolley
BACKGROUND: Photographic stimuli are commonly used to assess cue reactivity in the research and treatment of alcohol use disorder. The stimuli used are often non-standardized, not properly validated, and poorly controlled. There are no previously published, validated, American-relevant sets of alcohol images created in a standardized fashion. OBJECTIVES: We aimed to: 1) make available a standardized, matched set of photographic alcohol and non-alcohol beverage stimuli, 2) establish face validity, the extent to which the stimuli are subjectively viewed as what they are purported to be, and 3) establish construct validity, the degree to which a test measures what it claims to be measuring...
November 28, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27892692/changes-in-depression-mediate-the-effects-of-aa-attendance-on-alcohol-use-outcomes
#13
Claire E Wilcox, J Scott Tonigan
BACKGROUND: Depression may contribute to increased drinking in individuals with alcohol use disorder. Although Alcoholics Anonymous (AA) attendance predicts drinking reductions, there is conflicting information regarding the intermediary role played by reductions in depression. OBJECTIVES: We explored whether AA attendance reduces depressive symptoms, the degree to which improvement in depression results in reductions in drinking, and in which subgroups these effects occur...
November 28, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27929656/epilogue-to-special-issue-on-tobacco-and-other-substance-use-disorders-links-and-implications
#14
Steven A Schroeder
This paper summarizes The American Journal of Drug and Alcohol Abuse special issue and offers suggestions for future steps. People who use alcohol or other addictive substances are much more likely to use tobacco. Yet, clinicians and scientists have long regarded these addiction categories as separate and unrelated. The resultant benign neglect of tobacco use has had disastrous consequences on patients. This special issue is an important step toward remedying that situation. It has reviewed what is known and what more needs to be discovered regarding the co-occurrence of tobacco use disorder (TUD) and other substance use disorders (SUDs)...
March 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27901590/introduction-to-special-issue-on-tobacco-and-other-substance-use-disorders-links-and-implications
#15
Theresa Winhusen
No abstract text is available yet for this article.
March 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27901585/a-review-of-positron-emission-tomography-studies-exploring-the-dopaminergic-system-in-substance-use-with-a-focus-on-tobacco-as-a-co-variate
#16
Thulasi Thiruchselvam, Saima Malik, Bernard Le Foll
With the evolving sensitivity of positron emission tomography (PET) and the emergence of novel radiotracers, greater insight has been gained into the dopaminergic system as it relates to substance use. In this review, we summarize PET investigations from the last ten years that explore the dopaminergic system in tobacco, alcohol, stimulant, opiates, and cannabis addiction. In light of the prevalence of substance co-use, this review will also explore the effect of tobacco and other substance abuse co-morbidity on the dopaminergic system across study samples in the reviewed literature...
March 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27740856/alcohol-and-nicotine-interactions-pre-clinical-models-of-dependence
#17
Josephine R Tarren, Selena E Bartlett
While the co-morbidity of alcohol (ethanol) and tobacco (nicotine) dependence is well described, the processes that underpin this strong connection are still under debate. With the increasing popularity of electronic cigarettes (e-cigarettes), it is now becoming more important to look to the neurobiological mechanisms involving alcohol and nicotine interactions to effectively treat a new generation of co-dependent individuals. Researchers have already recognized that the neuropathology produced by the combination of nicotine and ethanol is likely to produce an addictive nature very different to that of either one alone, and are employing a mixture of pre-clinical techniques to establish and investigate every stage in the development of both nicotine and ethanol-seeking behaviors...
March 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27589579/interactions-between-nicotine-and-drugs-of-abuse-a-review-of-preclinical-findings
#18
Stephen J Kohut
Polysubstance abuse is common among substance-use disorder patients, and nicotine is one of the most commonly co-used substances. Epidemiological and clinical laboratory studies suggest that nicotine, when combined with other drugs of abuse, increases intake of one or both substances. This review focuses on the preclinical literature regarding nicotine's interaction with alcohol, stimulants (i.e., cocaine, amphetamines), opioids (i.e., morphine, heroin), and Δ(9)-tetrahydrocannabinol (THC). The current understanding of how these various classes of abused drugs may interact with nicotine on behavioral, physiological, and pharmacological indices that may be important in maintaining co-use of one or both substances in human populations are highlighted...
March 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27532746/mechanisms-and-genetic-factors-underlying-co-use-of-nicotine-and-alcohol-or-other-drugs-of-abuse
#19
Sarah J Cross, Shahrdad Lotfipour, Frances M Leslie
Concurrent use of tobacco and alcohol or psychostimulants represents a major public health concern, with use of one substance influencing consumption of the other. Co-abuse of these drugs leads to substantial negative health outcomes, reduced cessation, and high economic costs, but the underlying mechanisms are poorly understood. Epidemiological data suggest that tobacco use during adolescence plays a particularly significant role. Adolescence is a sensitive period of development marked by major neurobiological maturation of brain regions critical for reward processing, learning and memory, and executive function...
March 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27494436/the-co-occurrence-of-nicotine-and-other-substance-use-and-addiction-among-youth-and-adults-in-the-united-states-implications-for-research-practice-and-policy
#20
Linda Richter, Brandie S Pugh, Philip H Smith, Samuel A Ball
BACKGROUND: The increasing popularity of non-cigarette nicotine products, especially among youth, highlights the need for greater attention to their potential risks, including nicotine addiction and other substance use and addiction. OBJECTIVES: To examine the extent to which nicotine product use co-occurs with other substance use and addiction among youth and adults, describe the demographic groups and types of nicotine products associated with an increased risk of such co-occurrence, and discuss implications for research, prevention, clinical practice, and policy...
March 2017: American Journal of Drug and Alcohol Abuse
journal
journal
25680
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"