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American Journal of Drug and Alcohol Abuse

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https://www.readbyqxmd.com/read/28806104/repetitive-transcranial-magnetic-stimulation-rtms-administration-to-heavy-cannabis-users
#1
Gregory L Sahlem, Nathaniel L Baker, Mark S George, Robert J Malcolm, Aimee L McRae-Clark
BACKGROUND: Cannabis use disorder (CUD) is a common condition with few treatments. Several studies in other substance use disorders have found that applying repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex (DLPFC) decreases cue-elicited craving and possibly decreases use. To date, there have been no studies attempting to use rTMS in CUD. OBJECTIVES: This study was conducted to determine if rTMS could be feasibly delivered to a group of non-treatment seeking CUD participants...
August 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28806102/effects-of-alcohol-consumption-on-blood-pressure-in-hypertensive-women
#2
Naomi Deirdre Lakshmi Fisher, Endel John Orav, Grace Chang
BACKGROUND: Problem drinking carries significant health burdens, including an increased risk of hypertension. The effect of chronic alcohol intake on blood pressure (BP) in women is understudied and poorly understood. OBJECTIVES: We sought to examine the relationships between drinking habits and BP in hypertensive women. METHODS: We analyzed drinking habits in 113 women followed in the Brigham and Women's Hospital Hypertension Clinic for at least one year...
August 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28806101/homeless-women-s-service-use-barriers-and-motivation-for-participating-in-substance-use-treatment
#3
Carole C Upshur, Darlene Jenkins, Linda Weinreb, Lillian Gelberg, Elizabeth Aaker Orvek
BACKGROUND: Homeless women are at high risk for substance use disorder (SUD), and are a growing proportion of the homeless population. However, homeless women experience barriers to engaging in substance use services. OBJECTIVES: Among homeless women with SUD, to explore service use, motivation to change, service barriers, and willingness to have substance use and mental health problems addressed in primary health care. METHODS: Women with SUD were sampled from 11 Health Care for the Homeless (HCH) primary care clinics in 9 states, yielding 241 with either an alcohol or drug use disorder who then completed questions about SUD services...
August 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28795846/a-novel-non-opioid-protocol-for-medically-supervised-opioid-withdrawal-and-transition-to-antagonist-treatment
#4
Gregory Rudolf, Jim Walsh, Abigail Plawman, Paul Gianutsos, William Alto, Lloyd Mancl, Vania Rudolf
BACKGROUND: The clinical feasibility of a novel non-opioid and benzodiazepine-free protocol was assessed for the treatment of medically supervised opioid withdrawal and transition to subsequent relapse prevention strategies. METHODS: A retrospective chart review of DSM-IV diagnosed opioid-dependent patients admitted for inpatient medically supervised withdrawal examined 84 subjects (52 males, 32 females) treated with a 4-day protocol of scheduled tizanidine, hydroxyzine, and gabapentin...
August 10, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28767275/recovery-high-schools-effect-of-schools-supporting-recovery-from-substance-use-disorders
#5
Andrew J Finch, Emily Tanner-Smith, Emily Hennessy, D Paul Moberg
BACKGROUND: Recovery high schools (RHSs) provide post-treatment education and recovery support for young people with substance use disorders (SUDs). This is the first quasi-experimental outcome study to determine RHS effectiveness relative to students in non-RHSs. OBJECTIVES: To examine effects of RHS attendance on academic and substance use outcomes among adolescents treated for SUDs 6 months after recruitment to the study. METHODS: A quasi-experimental design comparing outcomes for adolescents with treated SUDs who attended RHSs for at least 28 days versus a propensity-score balanced sample of students with treated SUDs who did not attend RHSs...
August 2, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28750179/effects-of-propofol-on-conditioned-place-preference-in-male-rats-involvement-of-nitrergic-system
#6
Andleeb Shahzadi, Tuğçe Uskur, A Gökhan Akkan, Burcu Çevreli, Tayfun Uzbay
BACKGROUND: Drug-induced conditioned place preference (CPP) is linked to the addictive properties of the drug used. The number of studies that have investigated the effects of propofol on CPP is limited. Research findings suggest that nitric oxide (NO) might play an important role in substance use disorders. OBJECTIVES: The present study sought to investigate the role of the nitrergic system on the rewarding effects of propofol by using the CPP protocol in rats...
July 27, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28750172/transgenerational-modification-of-hippocampus-tnf-%C3%AE-and-s100b-levels-in-the-offspring-of-rats-chronically-exposed-to-morphine-during-adolescence
#7
Jamal Amri, Mehdi Sadegh, Neda Moulaei, Mohammad Reza Palizvan
BACKGROUND: TNF-α and S100B are important signaling factors that are involved in many aberrant conditions of the brain. Chronic morphine exposure causes aberrant modifications in the brain. OBJECTIVES: We examined the consequences of chronic morphine consumption by parents before mating on hippocampus TNF-α and S100B levels in the parents and their offspring. METHODS: A total of 12 adult female and 12 adult male Wistar rats were used as parents...
July 27, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28742979/adult-attachment-and-drinking-context-as-predictors-of-alcohol-problems-and-relationship-satisfaction-in-college-students
#8
Elise C Hocking, Raluca M Simons, Jeffrey S Simons, Harry Freeman
BACKGROUND: Evidence suggests that for young adults, intimate partners influence each other's drinking patterns. Therefore, exploration of variables related to intimate partner relationships (such as attachment style) could broaden the current understanding of risk factors for alcohol problems in this demographic. OBJECTIVES: The current study examined the role of drinking context in the relationships among insecure attachment, alcohol problems, and relationship satisfaction...
July 25, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28726525/working-memory-capacity-and-addiction-treatment-outcomes-in-adolescents
#9
Jon M Houck, Sarah W Feldstein Ewing
BACKGROUND: Brief addiction treatments including motivational interviewing (MI) have shown promise with adolescents, but the factors that influence treatment efficacy in this population remain unknown. One candidate is working memory, the ability to hold a fact or thought in mind. This is relevant, as in therapy, a client must maintain and manipulate ideas while working with a clinician. Working memory depends upon brain structures and functions that change markedly during neurodevelopment and that can be negatively impacted by substance use...
July 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28726520/rural-and-urban-substance-use-differences-effects-of-the-transition-to-college
#10
Karen J Derefinko, Zoran Bursac, Michael G Mejia, Richard Milich, Donald R Lynam
BACKGROUND: With approximately 20% of Americans residing in rural communities, substance use differences is an important topic for appropriate use of resources, policy decisions, and the development of prevention and intervention programs. OBJECTIVES: The current study examined differences in alcohol, tobacco, and marijuana use among students from rural and urban backgrounds across the transition to college. METHODS: Participants were 431 (48% male) undergraduate students from a large, public southeastern university who provided yearly alcohol, tobacco, and marijuana use data during freshman, sophomore, and junior years...
July 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28726514/increased-blood-8-hydroxy-2-deoxyguanosine-levels-in-methamphetamine-users-during-early-abstinence
#11
Ming-Chyi Huang, Ying-Ching Lai, Shih-Ku Lin, Chun-Hsin Chen
BACKGROUND: Reactive oxygen species (ROS) are thought to play a role in the adverse physical and mental consequences of methamphetamine usage. The oxidative DNA adduct 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a well-known biomarker of ROS-induced DNA damage. Currently, there is insufficient clinical information about methamphetamine-induced oxidative DNA damage. OBJECTIVES: This study examined differences in blood levels of 8-OHdG between methamphetamine users and non-users as well as alterations in 8-OHdG levels after 2 weeks of methamphetamine abstinence...
July 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28726513/effects-of-depression-and-past-year-binge-drinking-on-cognitive-control-processes-during-a-flanker-task-in-college-aged-adults
#12
Arin M Connell, Sarah Danzo, Glen Dawson
BACKGROUND: Recent but largely separate literatures have examined neurocognitive alterations related to both depression and binge drinking, suggesting similar patterns of impairments in attention control and decisional processes. However, depression and problematic alcohol use tend to co-occur, and few studies have examined whether cognitive processing effects of depression and binge drinking are independent or interacting. OBJECTIVE: The current study examined joint effects of depressive symptoms and past-year binge drinking on cognitive processing (measured via EEG assessment)...
July 20, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28665694/surveying-the-opinions-of-pennsylvania-chiefs-of-police-toward-officers-carrying-and-administering-naloxone
#13
Paul A Smyser, Jeffrey S Lubin
BACKGROUND: Recent legislation in Pennsylvania allows police officers to administer naloxone to individuals in an opioid overdose. Pressure has subsequently been placed on police departments to adopt naloxone programs. OBJECTIVE: To survey Pennsylvania Chiefs of Police regarding potential obstacles to officer-administered naloxone, and their overall opinion toward such programs. METHODS: A confidential survey was administered at the Annual Conference for the Pennsylvania Chiefs of Police Association and online over the organization's listserv...
June 30, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28662359/distinctions-between-seeking-and-non-seeking-treatment-research-participants-implications-for-clinical-trials-effectiveness
#14
Laura Acion, Janet Zwick, L Paloma Rojas Saunero, Stephan Arndt
No abstract text is available yet for this article.
June 29, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28662358/interaction-between-the-adh1b-3-allele-and-drinking-motives-on-alcohol-use-among-black-college-students
#15
Michelle J Zaso, Jessica M Desalu, Jueun Kim, Kavita Suryadevara, John M Belote, Aesoon Park
BACKGROUND: Black young adults have lower rates of alcohol use than other racial groups. Genetic factors may protect against drinking. Specifically, the ADH1B*3 allele is present almost exclusively in Black populations and has been protective against alcohol use and alcohol use disorder. The protective effects of the ADH1B*3 allele, however, may differ as a function of alcohol-promoting cognitions. OBJECTIVES: The current study examined whether ADH1B*3 moderated relations of drinking motives with alcohol consumption among Black college drinkers...
June 29, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28662352/longitudinal-associations-between-outpatient-medical-care-use-and-substance-use-among-rural-stimulant-users
#16
Michael A Cucciare, Xiaotong Han, Christine Timko, Nickolas Zaller, Kristina M Kennedy, Brenda M Booth
BACKGROUND: Negative views toward substance use treatment among some rural substance users and limited treatment resources in rural areas likely affect substance use utilization. It is therefore important to determine whether accessing healthcare options other than substance use treatment, specifically outpatient medical care (OMC), is associated with reductions in substance use. OBJECTIVES: We examined whether use of OMC was associated with reductions in substance use among rural substance users over a three-year period...
June 29, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28662343/effect-of-chronic-%C3%AE-hydroxybutyrate-ghb-administration-on-ghb-toxicokinetics-and-ghb-induced-respiratory-depression
#17
Bridget L Morse, Gurkishan S Chadha, Melanie A Felmlee, Kristin E Follman, Marilyn E Morris
BACKGROUND: γ-hydroxybutyrate (GHB) has a high potential for illicit use; overdose of this compound results in sedation, respiratory depression and death. Tolerance to the hypnotic/sedative and electroencephalogram effects of GHB occurs with chronic GHB administration; however, tolerance to respiratory depression has not been evaluated. GHB toxicodynamic effects are mediated predominantly by GABAB receptors. Chronic treatment may affect monocarboxylate transporters (MCTs) and alter the absorption, renal clearance and brain uptake of GHB...
June 29, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28650668/categorization-of-psychoactive-substances-into-hard-drugs-and-soft-drugs-a-critical-review-of-terminology-used-in-current-scientific-literature
#18
Peter Janik, Michaela Kosticova, Jan Pecenak, Michal Turcek
BACKGROUND: Precise terminology and definitions are important components of scientific language. Although the terms "hard drugs" and "soft drugs" are used widely by professionals, neither the International Classification of Diseases nor the Diagnostic and Statistical Manual classify psychoactive substances into the categories "hard" and "soft." OBJECTIVES: To analyze the occurrence of the terms "hard drugs" and "soft drugs" in recent scientific literature and to establish the degree of consensus in labeling psychoactive substances as "hard" or "soft...
June 26, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28621562/association-between-alcohol-consumption-trajectories-and-clinical-profiles-among-women-and-men-living-with-hiv
#19
Natalie E Kelso-Chichetto, Michael Plankey, Alison G Abraham, Nicole Ennis, Xinguang Chen, Robert Bolan, Robert L Cook
BACKGROUND: Alcohol use is common among persons living with HIV (PLWH). It is unclear how alcohol consumption changes over time and if these changes are associated with clinical profiles. OBJECTIVE: We aimed to describe the association between longitudinal patterns of alcohol consumption and the clinical profiles of PLWH. METHODS: Data from the Women's Interagency HIV Study (n = 1123 women) and Multicenter AIDS Cohort Study (n = 597 men) from 2004 to 2013 were utilized...
June 16, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28613973/the-association-of-cannabis-use-on-inpatient-psychiatric-hospital-outcomes
#20
Melanie Rylander, Helena R Winston, Haley Medlin, Madelyne Hull, Abraham Nussbaum
BACKGROUND: The associations between cannabis use and psychosis are well documented in numerous studies. There is a need to evaluate the impact of cannabis use on inpatient psychiatric utilization and outcomes. OBJECTIVES: To evaluate the impact of cannabis use on psychiatric hospital outcomes. METHODS: This study was conducted between April 20, 2015 and October 20, 2015. All patients (n = 120) admitted to Denver Health with psychotic symptoms were administered a urine toxicology screening testing for the presence of 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol (THC-COOH, the active metabolite of cannabis)...
June 14, 2017: American Journal of Drug and Alcohol Abuse
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