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Journal of Rheumatology

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https://www.readbyqxmd.com/read/27980015/predicting-which-children-with-juvenile-idiopathic-arthritis-will-have-a-severe-disease-course-results-from-the-reacch-out-cohort
#1
Jaime Guzman, Andrew Henrey, Thomas Loughin, Roberta A Berard, Natalie J Shiff, Roman Jurencak, Susanne M Benseler, Lori B Tucker
OBJECTIVE: We studied an inception cohort of children with juvenile idiopathic arthritis (JIA) to (1) identify distinct disease courses based on changes over 5 years in 5 variables prioritized by patients, parents, and clinicians; and (2) estimate the probability of a severe disease course for each child at diagnosis. METHODS: Assessments of quality of life, pain, medication requirements, patient-reported side effects, and active joint counts were scheduled at 0, 6, 12, 18, 24, 36, 48, and 60 months...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980014/stiffness-is-the-cardinal-symptom-of-inflammatory-musculoskeletal-diseases-yet-still-variably-measured-report-from-the-omeract-2016-stiffness-special-interest-group
#2
Serena Halls, Premarani Sinnathurai, Sarah Hewlett, Sarah L Mackie, Lyn March, Susan J Bartlett, Clifton O Bingham, Rieke Alten, Ina Campbell, Catherine L Hill, Robert J Holt, Rod Hughes, John R Kirwan, Amye L Leong, Ying Ying Leung, Anne Lyddiatt, Lorna Neill, Ana-Maria Orbai
OBJECTIVE: The objectives of the Outcome Measures in Rheumatology (OMERACT) Stiffness special interest group (SIG) are to characterize stiffness as an outcome in rheumatic disease and to identify and validate a stiffness patient-reported outcome (PRO) in rheumatology. METHODS: At OMERACT 2016, international groups presented and discussed results of several concurrent research projects on stiffness: a literature review of rheumatoid arthritis (RA) stiffness PRO measures, a qualitative investigation into the RA and polymyalgia rheumatica patient perspective of stiffness, data-driven stiffness conceptual model development, development and testing of an RA stiffness PRO measure, and a quantitative work testing stiffness items in patients with RA and psoriatic arthritis...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980013/histopathological-classification-and-renal-outcome-in-patients-with-antineutrophil-cytoplasmic-antibodies-associated-renal-vasculitis-a-study-of-186-patients-and-metaanalysis
#3
Yong-Xi Chen, Jing Xu, Xiao-Xia Pan, Ping-Yan Shen, Xiao Li, Hong Ren, Xiao-Nong Chen, Li-Yan Ni, Wen Zhang, Nan Chen
OBJECTIVE: Renal vasculitis is one of the most common manifestations of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) and renal histology is a key predictor of the outcome. A new histopathologic classification was proposed and validated, but the results are still debated. METHODS: We performed a retrospective analysis to validate the histopathologic classification and performed a metaanalysis to evaluate its predictive value. There were 186 patients with ANCA-associated renal vasculitis diagnosed at Ruijin Hospital who were enrolled in the retrospective study...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980012/baseline-shoulder-ultrasonography-is-not-a-predictive-marker-of-response-to-glucocorticoids-in-patients-with-polymyalgia-rheumatica-a-12-month-followup-study
#4
Maria Concetta Miceli, Angelo Zoli, Giusy Peluso, Silvia Bosello, Elisa Gremese, Gianfranco Ferraccioli
OBJECTIVE: In this study, we evaluated whether ultrasound (US) subdeltoid bursitis (SB) and/or biceps tenosynovitis (BT) presence at baseline could represent a predictive marker of response to standard therapy after 12 months of followup, and whether a positive US examination could highlight the need of higher maintenance dosage of glucocorticoids (GC) at 6 and 12 months in patients with polymyalgia rheumatica (PMR). METHODS: Sixty-six consecutive patients with PMR underwent bilateral shoulder US evaluations before starting therapy and after 12 months of followup...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980011/mapping-the-effect-of-psoriatic-arthritis-using-the-international-classification-of-functioning-disability-and-health
#5
Tania Gudu, Uta Kiltz, Maarten de Wit, Tore Kristian Kvien, Laure Gossec
OBJECTIVE: The effect of a disease can be categorized by a standardized reference system: the International Classification of Functioning, Disability and Health (ICF). The objective was to map the effect of psoriatic arthritis (PsA) from the patient's perspective to the ICF. METHODS: A systematic literature review was performed. Qualitative publications reporting domains of impact important for patients with PsA were identified using the following terms: ("psoriatic arthritis") AND ("quality of life" OR "impact")...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980010/predictors-of-mortality-in-people-with-recent-onset-gout-a-prospective-observational-study
#6
Zoë L Vincent, Greg Gamble, Meaghan House, Julie Knight, Anne Horne, William J Taylor, Nicola Dalbeth
OBJECTIVE: To determine mortality rates and predictors of death at baseline in people with a recent onset of gout. METHODS: People with gout disease duration < 10 years were recruited from primary and secondary care settings. Comprehensive clinical assessment was completed at baseline. Participants were prospectively followed for at least 1 year. Information about death was systematically collected from primary and secondary health records. Standardized mortality ratios (SMR) were calculated and risk factors for mortality were analyzed using Cox proportional hazard regression models...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980009/understanding-how-the-diagnostic-delay-of-spondyloarthritis-differs-between-women-and-men-a-systematic-review-and-metaanalysis
#7
Vega Jovaní, Mar Blasco-Blasco, M Teresa Ruiz-Cantero, Eliseo Pascual
OBJECTIVE: To identify empirical evidence of diagnostic delay in spondyloarthritis (SpA), determine whether sex-related differences persist, and conduct an analysis from that perspective of the possible causes, including the influence of quality research, in this group of inflammatory rheumatic diseases. METHODS: A systematic review was done of delay in diagnosis of SpA in MEDLINE and EMBASE and other sources. Study quality was determined in line with the Strengthening The Reporting of OBservational studies in Epidemiology (STROBE) statement...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980008/the-pharmacodynamics-pharmacokinetics-and-safety-of-arhalofenate-in-combination-with-febuxostat-when-treating-hyperuricemia-associated-with-gout
#8
Alexandra S Steinberg, Bradley D Vince, Yun-Jung Choi, Robert L Martin, Charles A McWherter, Pol F Boudes
OBJECTIVE: Arhalofenate (ARH), in development for gout, has uricosuric and anti-flare activities. ARH plus febuxostat (FBX) were evaluated in subjects with gout for serum uric acid (SUA) lowering, drug interaction, and safety. METHODS: Open phase II trial in gout volunteers (NCT02252835). Cohort 1 received ARH 600 mg for 2 weeks, followed by sequential 1-week co-administration of FBX 80 mg followed by 40 mg. FBX 40 mg was continued alone for 2 weeks. Cohort 2 received ARH 800 mg for 2 weeks, followed by sequential 1-week co-administration of FBX 40 mg followed by 80 mg...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27980007/patient-reported-flares-in-ankylosing-spondylitis-a-cross-sectional-analysis-of-234-patients
#9
Charlotte Jacquemin, Walter P Maksymowych, Annelies Boonen, Laure Gossec
OBJECTIVE: Ankylosing spondylitis (AS) is characterized by periodic flares. The objective of this study was to assess the frequency of patient-reported flares and their related factors. METHODS: This cross-sectional study analyzed the 2004 data of a Canadian cohort. Participants had AS according to the modified New York criteria. Current flare status ("Are you experiencing a current flare"?), number of flares over the past 3 months, their average duration, the Bath Ankylosing Spondylitis Disease Activity and Functional Index (BASDAI and BASFI, respectively), and the AS Quality of Life questionnaire were assessed by self-report...
December 15, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27909087/stand-up-and-be-counted-measuring-and-mapping-the-rheumatology-workforce-in-canada
#10
Claire E H Barber, Lauren Jewett, Elizabeth M Badley, Diane Lacaille, Alfred Cividino, Vandana Ahluwalia, Henry Averns, Cory Baillie, Janet Ellsworth, Janet Pope, Deborah Levy, Christine Charnock, Claire McGowan, J Carter Thorne, Cheryl Barnabe, Michel Zummer, Katie Lundon, Robert S McDougall, John G Thomson, Elaine A Yacyshyn, Dianne Mosher, Julie Brophy, Thanu Nadarajah Ruban, Deborah A Marshall
OBJECTIVE: To characterize the practicing rheumatologist workforce, the Canadian Rheumatology Association (CRA) launched the Stand Up and Be Counted workforce survey in 2015. METHODS: The survey was distributed electronically to 695 individuals, of whom 519 were expected to be practicing rheumatologists. Demographic and practice information were elicited. We estimated the number of full-time equivalent rheumatologists per 75,000 population from the median proportion of time devoted to clinical practice multiplied by provincial rheumatologist numbers from the Canadian Medical Association...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27909086/the-12-item-psoriatic-arthritis-impact-of-disease-questionnaire-construct-validity-reliability-and-interpretability-in-a-clinical-setting
#11
Marco Di Carlo, Andrea Becciolini, Valentina Lato, Chiara Crotti, Ennio Giulio Favalli, Fausto Salaffi
OBJECTIVE: To study, in a real-life setting, the construct validity, the reliability, and the interpretability of the 12-item Psoriatic Arthritis Impact of Disease (PsAID-12) questionnaire in patients with psoriatic arthritis (PsA). METHODS: In 144 consecutive patients with PsA (81 men and 63 women, mean age of 51.4 ± 12.8 yrs, and 77 receiving biologic treatment), the PsAID-12 and other patient-reported outcomes (PRO) were collected, such as the Dermatology Life Quality Index...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27909085/a-negative-antinuclear-antibody-does-not-indicate-autoantibody-negativity-in-myositis-role-of-anticytoplasmic-antibody-as-a-screening-test-for-antisynthetase-syndrome
#12
Rohit Aggarwal, Namrata Dhillon, Noreen Fertig, Diane Koontz, Zengbiao Qi, Chester V Oddis
OBJECTIVE: To evaluate the utility of anticytoplasmic autoantibody (anti-CytAb) in antisynthetase antibody-positive (anti-SynAb+) patients. METHODS: Anti-SynAb+ patients were evaluated for antinuclear antibody (ANA) and anti-CytAb [cytoplasmic staining on indirect immunofluorescence (IIF)] positivity. Anti-SynAb+ patients included those possessing anti-Jo1 and other antisynthetase autoantibodies. Control groups included scleroderma, systemic lupus erythematosus, Sjögren syndrome, rheumatoid arthritis, and healthy subjects...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27909084/sustained-benefits-of-exercise-based-motivational-interviewing-but-only-among-nonusers-of-opioids-in-patients-with-fibromyalgia
#13
Sunghye Kim, James E Slaven, Dennis C Ang
OBJECTIVE: Given the known side effects of opioids and their potential effects on cognition, we sought to evaluate the benefits of motivational interviewing (MI) to promote physical activity on 2 subsets of participants with fibromyalgia (FM): nonusers and users of opioids. METHODS: This was a secondary data analysis of a 36-week randomized controlled trial to assess the efficacy of MI to promote physical activity among participants with FM. Participants were randomized to 1 of 2 treatment arms: 6 phone-based MI sessions (n = 107) or 6 sessions of FM self-management instructions [attention control (AC), n = 109]...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27909083/continual-maintenance-of-remission-defined-by-the-acr-eular-criteria-in-daily-practice-leads-to-better-functional-outcomes-in-patients-with-rheumatoid-arthritis
#14
Kumi Shidara, Ayako Nakajima, Eisuke Inoue, Daisuke Hoshi, Naoki Sugimoto, Yohei Seto, Eiichi Tanaka, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka
OBJECTIVE: To evaluate longterm functional outcomes in rheumatoid arthritis (RA) based on the number of times that the American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) or the 28-joint Disease Activity Score (DAS28) remission criteria were fulfilled. METHODS: Patients with RA who participated in all 6 data collections in an observational cohort from 2008 to 2010 and who fulfilled the DAS28 remission criteria at baseline were studied...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27909081/five-year-efficacy-and-safety-of-tocilizumab-monotherapy-in-patients-with-rheumatoid-arthritis-who-were-methotrexate-and-biologic-naive-or-free-of-methotrexate-for-6-months-the-ambition-study
#15
Graeme Jones, Thomas Wallace, Matthew J McIntosh, Laura Brockwell, Juan J Gómez-Reino, Anthony Sebba
OBJECTIVE: To report on the 5-year efficacy and safety results of the AMBITION (Actemra versus Methotrexate double-Blind Investigative Trial In mONotherapy) monotherapy study (ClinicalTrials.gov: NCT00109408, NCT00720798). METHODS: Patients with rheumatoid arthritis for whom biologics had not failed or who did not discontinue methotrexate because of lack of efficacy or tolerability were followed up for 5 years to assess the efficacy and serious adverse events (SAE) of tocilizumab (TCZ) monotherapy...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27803133/comparison-of-the-phenotype-and-outcome-of-granulomatosis-with-polyangiitis-between-uk-and-japanese-cohorts
#16
Shunsuke Furuta, Afzal N Chaudhry, Yoshihiro Arimura, Hiroaki Dobashi, Shouichi Fujimoto, Sakae Homma, Niels Rasmussen, David R Jayne
OBJECTIVE: There are differences in the frequencies of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis subgroups between different geographic regions, and we have reported differences in the phenotype of microscopic polyangiitis between Europe and Japan. In this retrospective observational study, we compared phenotypes and outcomes of granulomatosis with polyangiitis (GPA) between the United Kingdom and Japan. METHODS: We identified 128 UK and 82 Japanese patients with GPA diagnosed between 2000 and 2012...
November 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/28042135/developing-a-risk-scoring-model-for-ankylosing-spondylitis-based-on-a-combination-of-hla-b27-single-nucleotide-polymorphism-and-copy-number-variant-markers
#17
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28042134/upregulation-of-thrombospondin-1-expression-in-synovial-tissues-and-plasma-of-rheumatoid-arthritis-role-of-transforming-growth-factor-%C3%AE-1-toward-fibroblast-like-synovial-cells
#18
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28042133/assessing-elementary-lesions-in-gout-by-ultrasound-results-of-an-omeract-patient-based-agreement-and-reliability-exercise
#19
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28042132/summary-findings-of-a-systematic-literature-review-of-the-ultrasound-assessment-of-bone-erosions-in-rheumatoid-arthritis
#20
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Journal of Rheumatology
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