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JPMA. the Journal of the Pakistan Medical Association

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https://www.readbyqxmd.com/read/28138197/hookworm-infestation-as-a-cause-of-melena-and-severe-anaemia-in-farmer
#1
Marvi Tariq, Syeda Maria Muzammil, Fareed Ahmed Shaikh, K M Inam Pal
Hookworm infections remain a major cause of morbidity in the developing world. Prevalence is highest in agricultural areas, where use of waste water for irrigation and poor hygiene increases infection rates among farmers. Infections present with gastrointestinal symptoms and chronic anaemia, and there are usually no signs of overt blood loss. The following report describes a case of melena in a middle-aged farmer, where the diagnosis of hookworm infestation was delayed due to the unusual presentation. The patient underwent multiple blood transfusions before referral to the Aga Khan University Hospital (AKUH), Karachi and was managed conservatively with mebendazole at our hospital after exclusion of other possible causes of gastrointestinal bleeding...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138196/superior-septal-approach-versus-left-atrial-approach-for-mitral-valve-replacement-a-retrospective-cohort-study
#2
Tooba Ansar, Taimur Asif Ali, Saneeha Shahid, Saulat Hasnain Fatimi, Ghulam Murtaza
OBJECTIVE: To compare the outcomes of superior septal approach and left atrial approach for mitral valve replacement. METHODS: This retrospective cohort study was conducted at the Aga Khan University Hospital, Karachi, and comprised records of patients who had undergone isolated mitral valve replacement from May 2003 to April 2012. Cases were reviewed for the outcomes [primary: loss of normal sinus rhythm; secondary: complications, residual defect and mortality]...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138195/barriers-and-bridges-to-insulin-therapy-bio-psychosocial-classification
#3
Sanjay Kalra, Samit Ghosal
Barriers to insulin therapy are a major challenge to optimal practice of primary care diabetes. The primary care practitioner has to contend with multiple barriers while trying to initiate appropriate insulin therapy in a timely manner. Proper understanding of these barriers allows for efficient bridging of them. This article proposes a bio psychosocial classification of the potential barriers to insulin therapy, and possible bridges which can be built to overcome them.
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138194/efficacy-and-safety-concerns-regarding-complementary-and-alternative-medicine-use-among-diabetes-patients
#4
Jothydev Kesavadev
There has been an ever increasing rise in the use of Complementary and Alternative Medicinal (CAM) practices among general populations during past few decades. Individuals with diabetes being prone to an array of related health complications, demand special attention concerning their interest towards different CAM practices. Apart from clinical practitioner and patient based awareness programmes regarding the safety and efficacy implications of CAM therapies, stringent regulations should also be imposed on these unconventional health practices so as to strike off any major adverse events...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138193/haemoperitoneum-due-to-ruptured-ovarian-cyst-in-a-13-year-old-girl-with-factor-v-deficiency-a-case-report
#5
Saba Laila Aslam, Muhammed Fareeduddin
Factor V deficiency is a rare autosomal recessive coagulation disorder. We are reporting a case of a 13 year old girl with factor V deficiency presenting as life threatening haemoperitoneum, following bleeding from ruptured ovarian cyst. Prolonged Prothrombin Time, Activated Partial Thromboplastin Time and a normal platelet count pointed towards a disorder of coagulation. Mixing study with factor V deficient plasma and coagulation factor assay revealed markedly reduced plasma factor V clotting activity.
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138192/a-rare-cause-of-recurrent-chest-infection-in-children-bronchopulmonary-sequestration
#6
Shabbir Hussain, Shoaib Ahmed, Syed Awais Ul Hassan Shah, Saba Haider Tarar
Bronchopulmonary sequestration is one of the rare thoracic congenital anomalies. We report the case of a 6 year old boy with history of recurrent episodes of chest infection and breathing difficulty. This time admitted with fever and cough. Investigations revelaed neutrophilic leucocytosis, raised C-reactive protein and a retrocardiac opacity on chest radiographs. Contrast enhanced Computed Topography(CT scan) revealed a large, well defined, left lower lobe multi-loculated cystic mass with a vessel arising from the descending aorta supplying sequestrated lung portion...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138191/intestinal-obstruction-due-to-congenital-malrotation-complicating-a-multiple-pregnancy-a-rare-case-report
#7
Yuzhu Yin, Chuo Li, Chengfang Xu, Lingling Wu, Ni Deng, Hongying Hou, Bin Wu
Intestinal obstruction due to congenital intestinal malrotation is usually diagnosed in neonates but may, in rare cases, occur during pregnancy. The absence of specific symptoms in combination with its low incidence makes timely detection of intestinal malrotation-related obstruction difficult in expectant mothers. We present a rare case of a 23-year-old woman with a twin pregnancy following in vitro fertilization-embryo transfer (IVF-ET) who presented with symptoms of intestinal obstruction at 22+4 weeks of gestation...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138190/effects-of-medical-and-mental-status-on-treatment-modalities-in-patients-treated-under-general-anaesthesia-at-the-ktu-faculty-of-dentistry-in-trabzon-turkey-a-comparative-retrospective-study
#8
Ozgul Baygin, Tamer Tuzuner, Adem Kusgoz, Gorkem Yahyaoglu, Nagehan Yilmaz, Simge Aksoy
This study evaluated the differences in dental conditions and treatment modalities between disabled and non-cooperative healthy children under general anaesthesia. The data were collected from paediatric patients between 3 and 15 years of age who received dental treatment under general anaesthesia. Patients with at least one mental/physical disturbance (group 1) and other healthy non-cooperative patients (group 2) were compared with regard to gender, age, weight, and treatment time-type. The statistical analyses were performed using Fisher's exact and Mann-Whitney U tests...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138189/medical-students-perception-of-the-progress-test-as-a-quality-controlled-assessment-tool-for-improving-learning-and-teaching-at-a-public-sector-medical-college-in-saudi-arabia
#9
Kamran Sattar, Tauseef Ahmad, Mahmoud Salah Khalil, Mona Mohamed Soliman, Gominda Giatry Punnamperuma, Hamza Mohammad Abdulghani
Progress test's distinguishing characteristics make it pertinent worldwide. We explored medical students' perceptions and opinions about Progress Test (PT) with a view to identifying areas concomitant with it's execution. This cross-sectional study took place at College of Medicine, Saudi Arabia, during the academic year 2015-16. A questionnaire (14 items) was administered. Reason for majority n=96 (89.7%) of the total participants to take the PT was their keenness to compare their academic standing with their peers from other participating medical colleges...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138188/skin-of-colour-characteristics-and-disease
#10
Zohra Zaidi
Skin colour varies from pale white to very dark. Fitzpatrick's skin phototypes are based on the person's skin colour and its response to sun exposure in terms of burning and tanning of the skin. Fitzpatrick's type 1V-V1 is known as the skin of colour and type 1-111 is the fair or white skin. The colour of the skin and texture of the hair are the most apparent phenotype to differentiate the different races; this correlates closely with the geography and ultraviolet radiation of the sun. There are notable differences in skin disease incidence, presentation, and treatment based on skin type...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138187/an-overview-on-phase-variation-mechanisms-and-roles-in-bacterial-adaptation
#11
Sajjad Ahmad, Mushtaq Ahmad, Salman Khan, Faisal Ahmad, Sabir Nawaz, Farman Ullah Khan
In nature, bacteria are exposed to multiple stress conditions posing threat to their life. However, bacteria evolve constantly and employ myriad of genetic and phenotypic strategies for successful survival. One such adaptive process is phase variation - a random, frequent and reversible ON/OFF switching of contingency genes generating phenotypical variations within the bacterial population. Pathogenic and commensal bacteria make use of this heritable process as a tool for adaptation, generating intra-strain diversity and immune evasion...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138186/relationship-of-seminal-free-l-carnitine-with-functional-spermatozoal-characteristics-results-from-an-observational-study-conducted-in-a-tertiary-care-hospital-of-karachi-pakistan
#12
Syed Danish Haseen Ahmed, Shahid Ahsan, Tehseen Iqbal, Syed Intesar Ahmed Burney
OBJECTIVE: To investigate the relationship of seminal free L-carnitine with functional spermatozoal characteristics. METHODS: This observational study was conducted at the Jinnah Postgraduate Medical Centre, Karachi, from August 2009 to June 2013, and comprised fertile and infertile subjects. Semen analysis was performed and reported for its volume, sperm count, motility and morphology according to the World Health Organisation's guidelines. Seminal free L-carnitine was estimated by high-performance liquid chromatography...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138185/cytogenetic-damage-in-the-buccal-cells-of-photocopying-workers-in-lahore-pakistan
#13
Houda Javed, Nadia Ghani
OBJECTIVE: To assess the genotoxic effects associated with workers in relation to the emissions at photocopying centres. METHODS: This case-control study was conducted at the Lahore College for Women University, Lahore, Pakistan, from August to November 2015, and comprised photocopying operators and controls. Micronuclei and other nuclear abnormalities in exfoliated buccal cells were analysed. A structured questionnaire was designed and interviews were conducted face-to-face...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138184/genexpert-a-new-tool-for-the-rapid-detection-of-rifampicin-resistance-in-mycobacterium-tuberculosis
#14
Muhammad Saeed, Shagufta Iram, Shahida Hussain, Adeel Ahmed, Mamoon Akbar, Maleeha Aslam
OBJECTIVE: To evaluate the diagnostic accuracy of GeneXpert assay for the detection of rifampicin resistance in mycobacterium tuberculosis using conventional drug susceptibility testing as gold standard. METHODS: This cross-sectional study was conducted at Jinnah Hospital, Lahore, / Allama Iqbal Medical College, Lahore, Pakistan, from January 2012 to December 2014, and comprised clinically and radiologically diagnosed tuberculosis suspected cases. Pulmonary and extra-pulmonary specimens were collected from strong tuberculosis suspects...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138183/spectrum-of-histopathological-diagnosis-in-paediatric-patients-with-liver-disorders-in-pakistan
#15
Syeda Shaheera Hashmi, Abu Bakar Hafeez Bhatti, Munir Iqbal Malik, Atif Rana, Humaira Nasir, Faisal Saud Dar, Ejaz Ahmed Khan
OBJECTIVE: To document spectrum of paediatric liver disorders confirmed on liver biopsy. METHODS: The retrospective review of patients was conducted at Shifa International Hospital, Islamabad, Pakistan, and comprised data of all children who underwent ultrasound-guided percutaneous liver biopsy between December 2008 and June 2015. Frequency of individual diagnosis was assessed and compared on gender basis. SPSS 16 was used for statistical analysis. RESULTS: There were medical records of 74 patients in the study with an overall median age of 6...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138182/gestational-diabetes-mellitus-and-the-predisposing-factors
#16
Syeda Sadia Fatima, Rehana Rehman, Faiza Alam, Sarosh Madhani, Bushra Chaudhry, Taseer Ahmed Khan
OBJECTIVE: To evaluate the occurrence of gestational diabetes mellitus and its association with demographic and anthropometric variables in pregnant women. METHODS: This cross-sectional study was conducted at the Aga Khan University Hospital, Abbasi Shaheed Hospital and Memon Hospital in Karachi, from February 2014 to December 2015, and comprised pregnant women who were screened by 75-g 2-hour oral glucose tolerance test, (24-28 weeks of gestation) and classified as per the criteria of the International Association of Diabetes and Pregnancy Study Group...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138181/patients-knowledge-on-rheumatoid-arthritis-a-study-at-a-tertiary-care-hospital
#17
Zarghoona Khalil, Babur Salim, Amjad Nasim, Sakina Malik
OBJECTIVE: To determine the level of disease awareness among patients of rheumatoid arthritis. METHODS: The cross-sectional study was conducted at the Fauji Foundation Hospital, Rawalpindi, Pakistan, from January to June 2015, and comprised patients with rheumatoid arthritis. A self-made questionnaire was used which was translated in Urdu. The questionnaire had three sets of questions. The first set gathered information on the gender, age, level of education and the duration of the disease of the patient...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138180/histopathological-pattern-of-benign-endoscopic-gastric-biopsies-in-western-saudi-arabia-a-review-of-1236-cases
#18
Zeinab Moustafa Elsawaf, Abdulkader Mohammed Albasri, Akbar Shah Hussainy, Ahmed Safar Alhujaily
OBJECTIVE: To determine the histopathological pattern of gastritis and benign gastric diseases in western Saudi Arabia. METHODS: TThis retrospective histopathology-based study was conducted in a tertiary care hospital in Madinah, Saudi Arabia, and comprised medical records of all patients who were diagnosed to have benign gastric diseases from January 2006 to December 2015.SPSS 19 was used for data analysis. RESULTS: Of the 1,236 patients, 669(54...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138179/thiopental-versus-ketofol-in-paediatric-sedation-for-magnetic-resonance-imaging-a-randomized-trial
#19
Yasemin Burcu Ustun, Yunus Oktay Atalay, Ersin Koksal, Cengiz Kaya, Fatih Ozkan, Elif Bengi Sener, Ahmet Veysel Polat
OBJECTIVE: To compare the efficiency of intravenous thiopental against intravenous ketamine-propofol combination in paediatric sedation for magnetic resonance imaging. METHODS: This prospective study was conducted at Ondokuz Mayis University Hospital, Samsun, Turkey, from July 1, 2014, to January 1, 2015, and comprised children aged 1 month to 12 years undergoing elective magnetic resonance imaging who were randomly assigned to two equal groups. Group I received thiopental 3 mg/kg intravenously followed by an additional dose of thiopental 1 mg/kg to achieve a Ramsay sedation score of 4...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138178/validation-of-respiratory-questionnaire-for-lung-function-assessment-among-an-occupational-group-of-textile-workers-in-pakistan
#20
Tanzil Jamali, Asaad Ahmed Nafees
OBJECTIVE: To determine the association of spirometric lung pattern with respiratory symptoms and to validate the American Thoracic Society respiratory questionnaire for lung function assessment among textile workers. METHODS: This cross-sectional survey was conducted from August to December 2009 among adult textile workers of Karachi. Data was collected through the American Thoracic Society Division of Lung Disease respiratory questionnaire and the lung function was assessed by using a spirometer...
February 2017: JPMA. the Journal of the Pakistan Medical Association
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