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Medicine (Baltimore)

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https://www.readbyqxmd.com/read/28614271/serum-anti-pla2r-antibody-and-glomerular-pla2r-deposition-in-chinese-patients-with-membranous-nephropathy-a-cross-sectional-study
#1
Lu Pang, Ai-Min Zhang, Hai-Xia Li, Jia-Lin Du, Li-Li Jiao, Nan Duan, Yi Liu, Dan Yu
M-type phospholipase A2 receptor (PLA2R) is the major target antigen in primary membranous nephropathy (PMN). Previous studies have evaluated the diagnostic value of serum anti-PLA2R antibody. However, the correlation of serum anti-PLA2R antibody and glomerular PLA2R deposition, and their association with clinical characteristics need to be further evaluated.A total of 136 patients were involved as inception group because serum anti-PLA2R antibody and glomerular PLA2R antigen were simultaneously measured. We examined serum anti-PLA2R antibody by ELISA and glomerular PLA2R deposition by immunofluorescence assay...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614270/computer-tomography-urography-assisted-real-time-ultrasound-guided-percutaneous-nephrolithotomy-on-renal-calculus
#2
You-Qiang Fang, Jie-Ying Wu, Teng-Cheng Li, Hao-Feng Zheng, Guan-Can Liang, Yan-Xiong Chen, Xiao-Bin Hong, Wei-Zhong Cai, Zhi-Jun Zang, Jin-Ming Di
This study aimed to assess the role of pre-designed route on computer tomography urography (CTU) in the ultrasound-guided percutaneous nephrolithotomy (PCNL) for renal calculus.From August 2013 to May 2016, a total of 100 patients diagnosed with complex renal calculus in our hospital were randomly divided into CTU group and control group (without CTU assistance). CTU was used to design a rational route for puncturing in CTU group. Ultrasound was used in both groups to establish a working trace in the operation areas...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614269/comparison-of-preoperative-imaging-and-pathological-findings-for-pancreatic-head-adenocarcinoma-a-retrospective-analysis-by-the-association-fran%C3%A3-aise-de-chirurgie
#3
Marine Gilabert, Jean-Marie Boher, Jean-Luc Raoul, François Paye, Philippe Bachellier, Olivier Turrini, Jean Robert Delpero
Initial imaging of pancreatic ductal adenocarcinoma is of crucial importance in the decision-making process. The aim of this study was to compare preoperative imaging, pathological data, and outcomes in a series of patients who underwent resection for pancreatic head cancer.From January 2004 to December 2009, data were collected by the Association Française de Chirurgie on 1044 patients who received first-line R0 resection of pancreatic head cancer.On imaging (computed tomography scan 97%, echoendoscopic ultrasound 61...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614268/pulmonary-and-cutaneous-infection-caused-by-nocardia-farcinica-in-a-patient-with-nephrotic-syndrome-a-case-report
#4
Ning Zhu, Yuan Zhu, Yi Wang, Shaoshao Dong
RATIONALE: Nocardia species is known as conditional pathogenic bacteria. Disseminated infection caused by Nocardia species is rare and occurs primarily in immunosuppressed patients. Signs and symptoms of this infection are frequently nonspecific making early diagnosis and treatment difficult. PATIENT CONCERNS: We report a case of subcutaneous and pulmonary nocardiosis due to Nocardia farcinica (N farcinica) in a patient with nephrotic syndrome who is undergoing long-term corticosteroid therapy...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614267/regional-cost-and-experience-not-size-or-hospital-inclusion-helps-predict-aco-success
#5
John Schulz, Matthew DeCamp, Scott A Berkowitz
The Medicare Shared Savings Program (MSSP) continues to expand and now includes 434 accountable care organizations (ACOs) serving more than 7 million beneficiaries. During 2014, 86 of these ACOs earned over $300 million in shared savings payments by promoting higher-quality patient care at a lower cost.Whether organizational characteristics, regional cost of care, or experience in the MSSP are associated with the ability to achieve shared savings remains uncertain.Using financial results from 2013 and 2014, we examined all 339 MSSP ACOs with a 2012, 2013, or 2014 start-date...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614266/the-effect-of-public-reporting-presentation-on-patients-decision-making-an-experimental-survey-in-yunan-province-china
#6
Chenxi Liu, Yuqing Tang, Dan Wang, Xinping Zhang
Public reporting of comparative performance information (PRCPI) influence patients' decision making and optimal presentation of PRCPI is urgently required for successful patients' engagement and quality improvement. This study was to explore the presentation of PRCPI impacting on consumers' decision making.This research applied a controlled design, with participants allocated randomly to 6 groups, and a total of 515 participants were recruited in Yunnan province. Five aspects of PRCPI presentations were evaluated, including display (star rating vs numeric information), and whether information was simplified, interpreted, overload, or ranked...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614265/prognostic-value-of-tumor-volume-and-radiation-dose-in-moderate-sized-hepatocellular-carcinoma-a-multicenter-analysis-in-korea-krog-14-17
#7
Myungsoo Kim, Chul Seung Kay, Won Il Jang, Mi-Sook Kim, Dong Soo Lee, Hong Seok Jang
The purpose of this study is to investigate the prognostic value of tumor volume and radiation dose for predicting treatment outcomes in moderate-sized hepatocellular carcinoma (HCC).A total of 72 patients with unresectable HCC ranging in size from 5 to 10 cm were treated with high-dose radiotherapy including hypofractionated radiotherapy (HRT) and stereotactic body radiotherapy (SBRT), in 3 institutions from 2003 to 2013. The HRT doses ranged from 33 to 60 Gy in 3 to 10 fractions. The primary endpoint was local progression-free survival (PFS); the secondary endpoints were overall PFS, overall survival (OS), and treatment toxicity...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614264/extremely-low-frame-rate-digital-fluoroscopy-in-catheter-ablation-of-atrial-fibrillation-a-comparison-of-2-versus-4-frame-rate
#8
Ji Hyun Lee, Jun Kim, Minsu Kim, Jongmin Hwang, You Mi Hwang, Joon-Won Kang, Gi-Byoung Nam, Kee-Joon Choi, You-Ho Kim
Despite the technological advance in 3-dimensional (3D) mapping, radiation exposure during catheter ablation of atrial fibrillation (AF) continues to be a major concern in both patients and physicians. Previous studies reported substantial radiation exposure (7369-8690 cGy cm) during AF catheter ablation with fluoroscopic settings of 7.5 frames per second (FPS) under 3D mapping system guidance. We evaluated the efficacy and safety of a low-frame-rate fluoroscopy protocol for catheter ablation for AF.Retrospective analysis of data on 133 patients who underwent AF catheter ablation with 3-D electro-anatomic mapping at our institute from January 2014 to May 2015 was performed...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614263/misdiagnosed-anomalous-left-coronary-artery-from-the-pulmonary-artery-as-endocardial-fibroelastosis-in-infancy-a-case-series
#9
Fan Ma, Kaiyu Zhou, Xiaoqing Shi, Xiaoqing Wang, Yi Zhang, Yifei Li, Yimin Hua, Chuan Wang
INTRODUCTION: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare but severe congenital cardiac malformation. The prognosis mainly depends on the early and accurate diagnosis and treatment. However, without a typical and specific clinical manifestation in early stage, ALCAPA has a higher rate of false initial diagnosis. DIAGNOSTIC AND THERAPEUTIC PROCEDURE: Three infants with impaired left ventricle (LV) function, LV enlargement, mitral valve regurgitation (MR), and LV endocardium thickness were initially diagnosed as endocardial fibroelastosis (EFE)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614262/minimally-invasive-mitral-valve-replacement-is-a-safe-and-effective-surgery-for-patients-with-rheumatic-valve-disease-a-retrospective-study
#10
Junyu Zhai, Lai Wei, Ben Huang, Chunsheng Wang, Hongqiang Zhang, Kanhua Yin
The aim of the study was to evaluate the treatment of minimally invasive mitral valve replacement (MIMVR) through a right minithoracotomy for patients with rheumatic mitral valve disease.From February 2009 to December 2016, 360 patients with rheumatic mitral valve disease underwent mitral valve replacement by the same surgeon. Among them, 150 patients accepted MIMVR through a right minithoracotomy, whereas the other 210 accepted a traditional median sternotomy. After matching by patients by age, sex, EuroSCORE, New York Heart Association (NYHA) classification, renal and liver function, and degree of mitral valve disease, we selected 224 patients for analysis in our retrospective study...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614261/a-prisma-compliant-meta-analysis-of-mdr1-polymorphisms-and-idiopathic-nephrotic-syndrome-susceptibility-and-steroid-responsiveness
#11
Shi-Sheng Han, Yan-Qiu Xu, Yan Lu, Xiang-Chen Gu, Yi Wang
BACKGROUND: Studies have investigated rs1128503, rs1045642, and rs2032582 in multidrug resistance protein 1 (MDR1) for association with susceptibility to idiopathic nephrotic syndrome (INS) and steroid resistance. However, because these findings were inconsistent, we performed a meta-analysis to determine whether there was evidence of a role of these MDR1 variants in INS. METHODS: The PubMed, Embase, and Web of Science databases were systematically searched to identify studies that examined MDR1 polymorphisms with susceptibility to INS and/or to steroid resistance...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614260/abnormal-octadeca-carbon-fatty-acids-distribution-in-erythrocyte-membrane-phospholipids-of-patients-with-gastrointestinal-tumor
#12
Shaohui Lin, Tianyu Li, Xifang Liu, Shihu Wei, Zequn Liu, Shimin Hu, Yali Liu, Hongzhuan Tan
Fatty acid (FA) composition is closely associated with tumorigenesis and neoplasm metastasis. This study was designed to investigate the differences of phospholipid FA (PLFA) composition in erythrocyte and platelet cell membranes in both gastrointestinal (GI) tumor patients and healthy controls.In this prospective study, 50 GI tumor patients and 33 healthy volunteers were recruited between the years 2013 and 2015. Blood samples were collected from healthy volunteers and patients, and FA composition was assessed using gas chromatography-mass spectrometer (GC-MS), and data were analyzed by multifactor regression analysis...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614259/global-regulator-soxr-is-a-negative-regulator-of-efflux-pump-gene-expression-and-affects-antibiotic-resistance-and-fitness-in-acinetobacter-baumannii
#13
Henan Li, Qi Wang, Ruobing Wang, Yawei Zhang, Xiaojuan Wang, Hui Wang
SoxR is a global regulator contributing to multidrug resistance in Enterobacteriaceae. However, the contribution of SoxR to antibiotic resistance and fitness in Acinetobacter baumannii has not yet been studied. Comparisons of molecular characteristics were performed between 32 multidrug-resistant A. baumannii isolates and 11 susceptible isolates. A soxR overexpression mutant was constructed, and its resistance phenotype was analyzed. The impact of SoxR on efflux pump gene expression was measured at the transcription level...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614258/the-malposition-of-a-central-venous-catheter-through-a-sheath-introducer-via-the-left-internal-jugular-vein-a-case-report
#14
Jung A Lim, Chan Hee Jee, Kyung-Hwa Kwak
RATIONALE: The misplacement of central venous catheter (CVC) can occur more often at the left jugular vein than the right side due to anatomic differences. And many of the previously reported cases are about catheter misplacement resulting from vessel penetration associated with guidewire. This case differs that the catheter itself through the sheath introducer can cause venous injury that may lead to the malposition of CVC particularly through an approach to the left internal jugular vein...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614257/enhancing-clinical-effectiveness-of-pre-radiotherapy-workflow-by-using-multidisciplinary-cooperating-e-control-and-e-alerts-a-squire-compliant-quality-improving-study
#15
Yung-Hsiang Lin, Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Chun-Liang Lai, Yi-Ting Shih, Pei-Han Yeh, Yi-An Lin, Wei-Ta Tsai, Hui-Ling Hsieh, Liang-Cheng Chen, Li-Wen Huang, Po-Hao Lin, Dai-Wei Liu, Feng-Chun Hsu, Shiang-Jiun Tsai, Jia-Chi Liu, En-Seu Chung, Hon-Yi Lin
Radiotherapy (RT) is useful in managing cancer diseases. In clinical practice, early initiation of RT is crucial for enhancing tumor control. But, delivering precise RT requires a series of pre-RT working processes in a tight staff-cooperation manner. In this regard, using information system to conduct e-control and e-alerts has been suggested to improve practice effectiveness; however, this effect is not well defined in a real-world RT setting.We designed an information system to perform e-control and e-alerts for the whole process of pre-RT workflow to shorten processing time, to improve overall staff satisfaction, and to enhance working confidence...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614256/association-between-chemokine-cxc-ligand-12-gene-polymorphism-rs1746048-and-coronary-heart-disease-a-moose-compliant-meta-analysis
#16
Min Chen, Yu-Feng Jiang, Nan-Nan Zhang, Hua-Jia Yang, Lang-Biao Xu, Qing Rui, Si-Jia Sun, Jia-Lu Yao, Ya-Feng Zhou
Recently a large number of investigations have implicated the association between the chemokine CXC ligand 12 gene polymorphism (rs1746048) and risk of coronary heart disease (CHD), but the results remain debatable. The aim of our study was to provide more compelling evidence for the relationship between rs1746048 and CHD risk. Studies eligible for this meta-analysis were identified through electronic search of PubMed, EMBASE, and CNKI. Two authors performed independent literature review and study quality assessment by using the Newcastle-Ottawa Scale checklist...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614255/identification-of-micrornas-as-diagnostic-biomarkers-for-acute-myocardial-infarction-in-asian-populations-a-systematic-review-and-meta-analysis
#17
Qian Wang, Junfen Ma, Zhiyun Jiang, Fan Wu, Jiedan Ping, Liang Ming
BACKGROUND: Acute myocardial infarction (AMI) is one of the leading causes of mortality and morbidity worldwide. Recently, several studies have revealed the diagnostic value of circulating microRNAs (miRNAs) for AMI detection. However, the diagnostic capacity of miRNAs for AMI is still controversial due to the inconsistent results among studies. METHODS: A systematic literature search was conducted to retrieve relevant articles in PubMed and other databases up to February 2017...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614254/relationship-of-diabetes-with-renal-dysfunction-in-hypertensive-adults
#18
Yuejuan Wang, Biyan Zhong, Youbao Li, Xianhui Qin, Binyan Wang, Xin Xu, Fanfan Hou, Yong Huo, Xiping Xu
We aimed to examine the relationship of diabetes with the estimated glomerular filtration rate (eGFR)-based renal function in the Chinese hypertensive adults.This cross-sectional analysis included a total of 18,641 hypertensive adults aged 45 to 75 years. The relationship of diabetes (a fasting glucose ≥7.0 mmol/L or self-reported use of hypoglycemic agents or physician diagnosed diabetes) with glomerular hyperfiltration (an absolute eGFR >90th percentile after adjusting for sex, age), hypofiltration (an eGFR <10th percentile and ≥60 mL/min/1...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614253/a-systematic-review-and-meta-analysis-into-the-effect-of-lateral-wedge-arch-support-insoles-for-reducing-knee-joint-load-in-patients-with-medial-knee-osteoarthritis
#19
Fei Xing, Bin Lu, Ming-Jie Kuang, Ying Wang, Yun-Long Zhao, Jie Zhao, Lei Sun, Yan Wang, Jian-Xiong Ma, Xin-Long Ma
OBJECTIVE: The aim of this study was to evaluate the immediate effects of lateral wedge arch support insoles (LWAS) on reducing the knee joint load in patients with medial knee osteoarthritis (OA) compared with an appropriate control. METHODS: Databases including Medline, EMBASE, Web of Science, Wiley Online Library, Cochrane library, and Google Scholar were searched with no limits on study date or language, from the earliest available date to October 31, 2016. The included studies had to have the aim of reducing knee load and have an appropriate control...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614252/suprascapular-nerve-entrapment-caused-by-an-intraosseous-ganglion-of-the-scapula-a-case-report
#20
Jung Ryul Kim, Sung Il Wang
RATIONALE: Suprascapular nerve compression is a rare but important entity that is often missed in clinical practice. Nerve dysfunction caused by an intraosseous ganglion of the glenoid is extremely rare, to the best of our knowledge, only 1 case of suprascapular nerve entrapment due to an intraosseous ganglion cyst has been reported previously in the published literature. PATIENT CONCERNS: We report a 61-year-old woman who had complained right shoulder pain that lasted over 3 years which was exacerbated by overhead activities...
June 2017: Medicine (Baltimore)
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