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Kurume Medical Journal

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https://www.readbyqxmd.com/read/29780064/systemic-lupus-erythematosus-and-sj%C3%A3-gren-s-syndrome-complicated-by-conversion-disorder-a-case-report
#1
Misa Nakamura, Seiji Tanaka, Tadashi Inoue, Yasuto Maeda, Kiyohito Okumiya, Takuya Esaki, G O Shimomura, Kenji Masunaga, Shinichiro Nagamitsu, Yushiro Yamashita
Conversion disorder (CD) is sometimes accompanied by motor and sensory impairments, such as muscle weakness, paralysis, sensory hypersensitivity, and sensory loss. Sjögren's syndrome (SS) complicates 5-10% of cases of systemic lupus erythematosus (SLE). Patients with SS or SLE present with various neurological symptoms and psychiatric manifestations. When neurological symptoms are present, it is important to distinguish whether the symptoms are caused by a neurological or a mental disorder because the former requires early intensive intervention, such as methylprednisolone pulse therapy (MPT), whereas psychotherapy or antidepressant drugs are recommended for mental disorders...
May 21, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29780063/the-effect-of-ozone-on-colonic-epithelial-cells
#2
Hidetomo Himuro
Due to its strong oxidation activity, ozone has been well known to kill bacteria and exert toxic effects on human tissues. At the same time, ozone is being used for the treatment of diseases such as inflammatory bowel disease in some European countries. However, the use of ozone for therapeutic purposes, despite its strong toxic effects, remains largely unexplored. Interestingly, we found that intrarectal administration of ozone gas induced transient colonic epithelial cell damage characterized by the impairment of cell survival pathways involved in DNA replication, cell cycle, and mismatch repair...
May 21, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29780062/effect-of-chlorella-ingestion-on-oxidative-stress-and-fatigue-symptoms-in-healthy-men
#3
Hirotaka Okada, Noriko Yoshida, Tatsuyuki Kakuma, Kouji Toyomasu
OBJECTIVE: We examined the effects of dietary chlorella ingestion on oxidative stress and fatigue symptoms in healthy men under resting and fatigue conditions. METHOD: We conducted a double-blind, parallel-arm controlled study. Twenty-seven healthy male volunteers (mean age, 35.4±10.4 years) were randomly divided into the chlorella and placebo groups, and received chlorella (6 g/day) and lactose as placebo (7.2 g/day), respectively, for 4 weeks. To simulate mild fatigue, subjects underwent exercise (40% of the heart rate reserve) for 30 minutes...
May 21, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29780061/a-retroaortic-left-renal-vein-in-a-female-cadaver
#4
Yoshiko Fujishima, Koichi Watanabe, Yoko Tabira, Joe Iwanaga, Yui Odo, Tsuyoshi Saga, R Shane Tubbs, Koh-Ichi Yamaki
We encountered a case of retroaortic left renal vein (RLRV) during an anatomical dissection course at our medical school in 2017. The case was a female cadaver who was 88 years old at death. Six roots of the left renal vein (RV) arose from the hilus of the kidney and joined to form one left renal vein, crossed dorsal to the abdominal aorta (AA) at the level of the second lumbar vertebra, and then drained into the inferior vena cava (IVC). Two roots joined at the right renal hilus to become the right RV to then drain into the IVC at the level of the first lumbar vertebral body...
May 21, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29780060/development-of-oropharyngeal-scope-type-ii-with-integrated-tongue-depressor-for-examination-of-the-oropharynx-ntop2016-study
#5
Koichi Tsunoda, Rika Kobayashi, Akiko Kada, Akiko M Saito, Y U Hanada, Hayato Misawa, Keizo Horibe, Tonghyo Chong, Miwako Honda, Yoko Morita, Osamu Komiyama
The oropharynx is examined by focusing an electric light, penlight, or forehead mirror on a desired visual field using a tongue depressor. However, it is extremely difficult to obtain objective recorded evidence for display with these methods, and the tools for examination have remained virtually unchanged for the past century. Treatment of the pharynx/oral cavity is exceedingly difficult, particularly in elderly patients and children. Therefore, there is an increasing need to develop a method for displaying the visual field during oropharyngeal examinations which is acceptable to patients, which can easily be applied at all medical institutions, which can be displayed to third parties, and which can be used by doctors for recording data and determining treatment...
May 21, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29553097/a-case-of-duplicated-right-vertebral-artery
#6
Mayuko Motomura, Koichi Watanabe, Yoko Tabira, Joe Iwanaga, Wakako Matsuuchi, Daichi Yoshida, Tsuyoshi Saga, Koh-Ichi Yamaki
We encountered a case of duplicated right vertebral artery during an anatomical dissection course for medical students in 2015. Two vertebral arteries were found in the right neck of a 91-year-old female cadaver. The proximal leg of the arteries arose from the area between the right subclavian artery and the right common carotid artery that diverged from the brachiocephalic artery. The distal leg arose from the right subclavian artery as expected. The proximal leg entered the transverse foramen of the fourth cervical vertebra and the distal leg entered the transverse foramen of the sixth cervical vertebra...
March 16, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29553096/a-randomized-trial-of-respiratory-status-during-airway-stenting-under-general-anesthesia-spontaneous-respiration-vs-controlled-ventilation-with-muscle-relaxants
#7
Sakura Okamoto, Hideo Saka, Masahide Oki, Namie Somiya, Sachiyo Yokoyama, Yoshihiro Mizutani, Akiko Kada, Akira Tomita
Airway stenting is a procedure in which a stent is inserted into a stenotic site in the airway. However, the optimal ventilation for airway stenting remains controversial. We have planned a randomized, unblinded controlled study to compare intraoperative respiratory status by dividing patients, who underwent airway stenting, into spontaneous respiration (SP) and controlled ventilation with muscle relaxants (MR) groups. This study started in April 2016. The subjects, patients aged ≥20 years with airway stenosis caused by malignant neoplasms for which airway stenting was scheduled, are randomly allocated to SP and MR groups...
March 16, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29553095/the-usefulness-of-piezoelectric-surgery-in-sagittal-split-ramus-osteotomy
#8
Akihiro Koba, Ryuichiro Tanoue, Shogo Kikuta, Shingo Hirashima, Yoshihiro Miyazono, Jingo Kusukawa
Mandibular osteotomy carries with it a risk of damaging blood vessels and nerves when using traditional surgical techniques. Piezosurgery® , is a new technique that uses ultrasonic vibration to enable bone-selective sectioning without damage to the surrounding soft tissues. However, paralysis may not be completely eliminated using Piezosurgery® for osteotomy. We investigated how piezoelectric surgery in bilateral sagittal splitting ramus osteotomy (BSSRO) affected the surrounding soft tissue. Forty-four patients with skeletal mandibular prognathism underwent mandibular setback with BSSRO...
March 16, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29553094/role-of-regulatory-t-cells-in-airway-inflammation-in-asthma
#9
Tomotaka Kawayama, Takashi Kinoshita, Kazuko Matsunaga, Yoshiko Naito, Jun Sasaki, Yoshikazu Tominaga, Tomoaki Hoshino
Asthma is an allergic disease characterized by chronic airway inflammation, airway hyperresponsiveness (AHR), reversibility and remodeling. Inhaled corticosteroids (ICS) are effective in many patients with asthma. However, ICS are a controlling, but not but curative treatment, and there are still many patients with refractory and difficult-to-treat asthma. The evaluation of airway inflammation by induced sputum, non-specific AHR by methacholine, and asthmatic reactions by specific allergen challenge techniques are useful not only to investigate the pathogenesis of asthma but also to help develop new drugs for asthma management...
March 16, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29249780/palliative-reirradiation-for-painful-bone-metastases-clinical-cases-and-literature-review
#10
Gen Suzuki, Hideya Yamazaki, Norihiro Aibe, Koji Masui, Naomi Sasaki, Kotoha Tatekawa, Daisuke Shimizu, Takuya Kimoto, Takeshi Nishimura, Akihiro Nakashima, Kei Yamada
Reirradiation to previously irradiated peripheral bone metastases for pain has been shown to be safe and effective, but no specific trial has been completed to define the indications for reirradiation of patients with recurrent symptoms of metastatic bone disease. Thus, we aimed to assess the effectiveness and prognostic factors of reirradiation for painful bone metastases. To do so, we reviewed the cases of 14 patients with painful bone metastases who had undergone reirradiation at our hospital. A favorable pain response after reirradiation was achieved in 50% (7/14) of the patients...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29176297/treatment-of-a-large-pharyngeal-venous-malformation-using-transoral-sclerotherapy
#11
Asako Kuhara, Norimitsu Tanaka, Tomoko Kugiyama, Masamichi Koganemaru, Kensuke Kiyokawa, Toshi Abe
Management of venous malformation (VM) in the pharynx is challenging because of difficulties in needle access and the presence of nerves as well as other critical anatomical structures around the lesion. We describe the successful treatment of a large pharyngeal VM using transoral sclerotherapy. The patient, a 21-yearold male, visited our hospital for sclerotherapy treatment consultation after complaining of difficulty in swallowing because of a pharyngeal VM. Transoral sclerotherapy was successful, and the symptoms showed complete alleviation...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29176296/periostin-expression-in-non-small-cell-lung-cancer-clinical-significance
#12
Daigo Murakami, Shinzo Takamori, Akihiko Kawahara, Masahiro Mitsuoka, Masaki Kashihara, Koichi Yoshiyama, Ryoichi Matsumoto, Shintaro Yokoyama, Kiminori Fujimoto, Atsushi Kawaguchi, Kenji Izuhara, Yoshito Akagi
Periostin is an extracellular matrix N-glycoprotein that is a major constituent of the desmoplastic stroma around solid tumors. Periostin promotes tumor invasion and metastasis via epithelial-mesenchymal transition. The aims of this study were to evaluate periostin expression immunohistochemically and quantitatively in patients with non-small cell lung cancer (NSCLC) and to assess any associations with clinical features and prognosis. A total of 184 specimens of NSCLC tissue were investigated, including 134 adenocarcinomas, 39 squamous cell carcinomas, and 11 other histologic subtypes...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29057760/anaplastic-thyroid-carcinoma-treated-with-lenvatinib
#13
Jun-Ichi Ohkubo, Azusa Takahashi, Shoji Ikezaki, Fumiko Takenaga, Yufu Ohkubo, Hideaki Suzuki
OBJECTIVE: We report a case of anaplastic thyroid carcinoma (ATC) with local recurrence and distant metastasis that responded very well to treatment with lenvatinib, a new molecular-targeted anticancer drug. CASE REPORT: A 91-year-old Japanese woman presented with a 5-month history of a painless mass in her left anterior neck. She had a past history of total thyroidectomy and neck dissection for papillary carcinoma of the thyroid. Here she underwent neck dissection, and the histopathological diagnosis was lymph node metastasis of papillary carcinoma with anaplastic transformation...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/29057759/novel-cadaver-injection-method-using-latex-and-magnetic-fluid
#14
Koichi Watanabe, Yoko Tabira, Tsuyoshi Saga, Joe Iwanaga, Wakako Matsuuchi, Daisuke Yamauchi, Hiroaki Tanaka, Shin-Ichiro Hashiguchi, Koh-Ichi Yamaki
Vascular injection into extracted tissue may be associated with leakage due to excessive local injection pressure. Historically, this complication has been impossible to resolve because the injection pressure has been the only available force with which to send the agent to the peripheral vasculature. We have developed a new vascular injection method that utilizes a material affected by magnetic force and is therefore not solely dependent upon the injection pressure. We mixed the same weights of latex and magnetic fluid and injected the solution into the arterial stump of an extracted tissue specimen...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/28674264/a-rare-case-of-ulcerative-colitis-with-neurofibromatosis-type-1
#15
Shuhei Fukunaga, Hidetoshi Takedatsu, Keiichi Mitsuyama, Takuji Torimura
Concomitant association of histologically proven inflammatory bowel disease (IBD) and neurofibromatosis type 1 (NF1) is a rare finding documented in only 5 adult clinical cases. A 34-year-old woman with known neurofibromatosis was admitted to our department with a 6-month history of intractable bloody diarrhea and abdominal pain. After a thorough clinical examination and paraclinical assessments, including colonoscopy and biopsy, ulcerative colitis (UC) was confirmed as the cause of gastrointestinal bleeding...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/28603158/long-term-prognosis-after-extracranial-intracranial-bypass-surgery-for-symptomatic-cerebrovascular-occlusive-disease
#16
Hideki Komatani, Yuji Okamoto, Takachika Aoki, Kei Noguchi, Motohiro Morioka
Prognosis after extracranial-intracranial (EC-IC) bypass surgery has only been studied for a few years and the benefits of this procedure are still controversial. In this single-center retrospective study, we examined the long-term prognosis of patients who underwent EC-IC bypass surgery. Subjects were patients with symptomatic internal carotid artery or intracranial lesion occlusive disease who underwent EC-IC bypass surgery between 1991 and 2003. Of these, long-term prognosis was examined in 57 patients (39 male, 18 female; mean age, 61...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/28603157/anatomical-and-radiological-analyses-of-l-shaped-kidney-with-vascular-anomalies
#17
Joe Iwanaga, Koichi Watanabe, Tsuyoshi Saga, Nobuhiro Tahara, Yoko Tabira, Ayano Sakuragi, Keiko Kaji, Kiyoshi Takahashi, Koh-Ichi Yamaki
L-shaped kidney is a congenital anomaly. The disorder results in the kidney appearing very similar in shape to horseshoe kidney (also a congenital anomaly), but either the right or left kidney is located at a position lower than the other kidney. In this report, we describe a woman with L-shaped kidney, identified during anatomical dissection, and compare the findings with clinical data obtained before her death. We discuss the embryology of L-shaped kidney based on detailed anatomical data on the kidney and its vascular system obtained by means of gross anatomical, radiological, and histological examinations...
February 26, 2018: Kurume Medical Journal
https://www.readbyqxmd.com/read/28381728/the-effects-of-psychoeducation-on-long-term-inpatients-with-schizophrenia-and-schizoaffective-disorder
#18
Nobuhiko Yanagida, Toshiro Uchino, Naohisa Uchimura
This study aimed to examine the significance of intervention to improve medication adherence in long-term inpatients by providing psychoeducation and then elucidating the effects of this training in terms of patient knowledge and attitudes. Subjects were patients who had been hospitalized for more than 1 year after being admitted to a psychiatric hospital, had been diagnosed as F2 (schizophrenia, schizoaffective disorder) according to the International Classification of Diseases, 10th Edition, and were capable of verbal communication...
May 8, 2017: Kurume Medical Journal
https://www.readbyqxmd.com/read/28381727/long-term-outcomes-of-pancreatic-function-following-pancreatic-trauma
#19
COMPARATIVE STUDY
Toshio Morita, Osamu Takasu, Teruo Sakamoto, Shinjirou Mori, Atsuo Nakamura, Masakazu Nabeta, Nobuhisa Hirayu, Mariko Moroki, Norio Yamashita
The objective of this study is to retrospectively assess long-term outcomes and late complications of pancreatic trauma. We studied 14 patients with pancreatic trauma who were treated at the Advanced Emergency Medical Service Center, Kurume University Hospital, between 1981 and 2012 and discharged alive. Relevant data were extracted from patient records and a retrospective patient questionnaire and blood test were completed to evaluate pancreatic function. The median patient age at the time of the survey was 49 years; the median post-injury period was 23 years and 5 months...
May 8, 2017: Kurume Medical Journal
https://www.readbyqxmd.com/read/28302934/hepatitis-b-vaccination-status-among-japanese-travelers
#20
COMPARATIVE STUDY
Kenichiro Yaita, Koji Yahara, Yoshiro Sakai, Jun Iwahashi, Kenji Masunaga, Nobuyuki Hamada, Hiroshi Watanabe
This study clarified the characteristics of travelers who received hepatitis B vaccinations. Subjects were 233 Japanese travelers who visited our clinic prior to travel. We summarized the characteristics of the clients and performed two comparative studies: first, we compared a hepatitis B-vaccinated group with an unvaccinated group; second, we compared a group that had completed the hepatitis B vaccine series with a group that did not complete the series. The hepatitis B vaccine was administered to 152 clients...
May 8, 2017: Kurume Medical Journal
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