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Journal of Postgraduate Medicine

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https://www.readbyqxmd.com/read/30147082/cabergoline-treatment-in-prolactinoma-amelioration-in-obstructive-and-central-sleep-apneas
#1
M Binar, O Karakoc, C Haymana, H Arslan
A 44-year-old male patient was admitted to the otolaryngology department with a history of progressive snoring, excessive daytime sleepiness, and reduced libido for the last 6 months. Polysomnography demonstrated the presence of moderate obstructive sleep apnea (OSA) with an apnea-hypopnea index (AHI) of 24.6 events/h, consisting of 77 obstructive and 59 central apneas. The marked number of central apneas in the sleep study and urologic complaints prompted the performance of brain magnetic resonance imaging (MRI), which indicated a pituitary macroadenoma (prolactinoma)...
August 24, 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30117480/recurrent-takotsubo-cardiomyopathy-in-a-postmenopausal-indian-lady-is-there-a-pattern
#2
N M Sharath Babu, S T Chacko, B R Chacko, A Irodi
Takotsubo cardiomyopathy (TTC) is a syndrome of acute left ventricular dysfunction with a clinical presentation often mimicking acute coronary syndrome. Without a high index of suspicion, this clinical entity often goes unrecognized. Although initially categorized as a benign completely reversible condition, it is no longer considered to be so. Recurrence of this condition, though rare, has been reported in a non-Indian population. We present a case of recurrent TTC in a postmenopausal Indian lady who had a similar clinical presentation both at the index event and at recurrence...
August 16, 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30306968/predatory-journals-the-rise-of-worthless-biomedical-science
#3
REVIEW
H Sharma, S Verma
In today's world when biomedical science is experiencing continuous threats from various sources, publication of research articles in predatory journals has created a major havoc. These predatory journals are publishing worthless biomedical science which will haunt genuine researchers and keen readers of authentic biomedical journals for several decades. Hence, researchers of various disciplines and academic experience should be continuously made aware of these predatory publishers and potential ways to recognize them...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30306967/proptosis-with-hemiplegia-unusual-presentation-of-multiple-myeloma
#4
K Ghosh
No abstract text is available yet for this article.
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30306966/measles-rubella-vaccination-campaign-a-trust-deficit
#5
A Sreedevi
No abstract text is available yet for this article.
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30306965/tele-evidence-comes-to-the-rescue-of-overburdened-medical-doctors
#6
A Aggrawal
No abstract text is available yet for this article.
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30264740/primary-osteogenic-sarcoma-of-the-skull-report-of-two-cases-with-review-of-literature
#7
R Singh, K Jha, I Pant, D Satti
Primary calvarial (excluding jaw) osteosarcoma is rare. We report two cases highlighting their unusual presentation and histopathologic variability - a 30-year-old female who presented with progressively increasing headache and a rapidly growing frontal swelling and a 16-year-old girl who had a rapidly growing mass in the left frontoparietal region which had recurred thrice but was otherwise asymptomatic. The lesions were osteolytic on neuroimaging and histopathological examination confirmed osteosarcoma. These two unusual cases are discussed along with a brief review of literature...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30264739/corkscrewing-of-retinal-arterioles-leading-to-diagnosis-of-coarctation-of-aorta
#8
A Shaik, K V Praveen Kumar, P Chiranjeevi, S Abdul Khader
Coarctation of aorta (CoA) usually leads to elevation of blood pressure above the site of obstruction and this elevated blood pressure probably gets transferred and is reflected in the retinal arterioles producing certain signs of hypertensive retinopathy. Fundus examination helps in differentiating hypertension due to CoA from other causes of juvenile hypertension, as corkscrewing of retinal arterioles is seen only in CoA but not in other conditions. A 16 year hypertensive male who was on antihypertensive treatment presented for routine checkup...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30226479/adult-teratoid-wilm-s-tumor-a-diagnostic-dilemma
#9
S Rajaian, M K Ramani, N S Kekre
No abstract text is available yet for this article.
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30207325/plasmacytoma-of-the-mesentery
#10
S M Thambi, S G Nair, R Benson
Extramedullary plasmacytoma represents 3%-5% of all plasma cell neoplasms. Plasmacytomas of the mesentery are extremely rare. We report the case of a 56-year-old man who presented with an abdominal mass and was diagnosed to have plasmacytoma of the mesentery. A literature review was also conducted on publications pertaining to solitary mesenteric plasmacytomas. These patients present late by which time the abdominal mass has reached a significant size. Radiation as a modality for local control has a limited role in treating mesenteric plasmacytomas...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30147083/neonatal-hyperlipidemia-with-pancreatitis-novel-gene-mutation-of-lipoprotein-lipase
#11
M H Shah, R Roshan, R Desai, S S Kadam
Lipoprotein lipase (LPL) deficiency is an autosomal recessive metabolic disorder with varying presentation in infancy and childhood, whereas clinical manifestations are rare in neonatal period. The estimated prevalence is one in a million births. A 23-day-old baby was admitted with complaints of fever, vomiting, and lethargy. Blood sample drawn appeared lipemic. Lipemia retinalis was noted on funduscopic examination. Biochemical analysis revealed abnormal lipid profile with severe hypertriglyceridemia (10,300 mg/dL) and elevated serum lipase level (517 IU/L) indicative of LPL deficiency with acute pancreatitis...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30136660/bilateral-massive-pneumonia-as-an-unusual-manifestation-of-puumala-hantavirus-infection
#12
H T Gozdas, D Menemenlioğlu, Y Coşgun, G Çelebi
Renal involvement due to European Puumala virus (PUUV) is frequent but pulmonary involvement is quite rare. We present here, a 24-year-old male with atypical clinical presentation of acute PUUV infection with gross pulmonary and minimal renal involvement. Severe pulmonary manifestations of PUUV infection, in this case, highlights that hantavirus infection should be considered in the differential diagnosis of atypical pneumonia.
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30117481/proptosis-and-hemiplegia-as-an-initial-manifestation-of-multiple-myeloma
#13
N Tahiliani, P Kataria, A Patel, P Kendre
Multiple myeloma (MM) is a monoclonal gammopathy, also known as the malignant proliferation of plasma cells, presenting with typical complications such as hypercalcemia, osteolytic bone lesions, anemia, renal insufficiency, and frequent infections. Central nervous system (CNS) involvement in MM in the form of parenchymal involvement is very uncommon and has been reported only in 1% of patients. CNS involvement as an initial presentation is very rare and has poor prognosis. Also specific treatment guidelines do not exist for the treatment of such patients...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30004038/peripheral-arterial-disease-and-risk-of-hip-fracture-a-systematic-review-and-meta-analysis-of-cohort-studies
#14
P Ungprasert, K Wijarnpreecha, C Thongprayoon, W Cheungpasitporn
Background: Previous studies have suggested an increased risk of hip fracture among patients with peripheral arterial disease (PAD), however, the results have been inconsistent. This meta-analysis was conducted with the aim to summarize all available evidence to better characterize the risk of incident hip fracture among these patients. Materials and Methods: A comprehensive literature review was conducted using the MEDLINE and EMBASE databases through October 2017 to identify all cohort and case-control studies that compared the risk of subsequent hip fracture between patients with PAD and individuals without PAD...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/29943747/tele-evidence-a-videoconferencing-tool-as-a-viable-alternative-to-physical-appearance-of-doctors-for-the-judicial-summons
#15
S Bari, P Arora, A K Gupta, M Singh, A K Aggarwal
Introduction: The role of physicians often extends beyond provision of direct patient care and includes appearance in courts as professional or expert witnesses to give their testimony in various legal cases. This often consumes precious time and resources of the doctors and the hospitals. This study was taken up to evaluate the present system of the physical appearance of the doctors to various courts and compare it with the videoconferencing mode of giving testimony (tele-evidence)...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/29943746/early-presentation-of-ruptured-post-traumatic-hepatic-artery-pseudoaneurysm
#16
M S Patel, V Shetty, A Shelake, A A Deshpande
Visceral artery aneurysms (VAA) are an uncommon but well recognized condition. Hepatic artery aneurysms (HAA) represent 14-20% of all visceral artery aneurysms. Post traumatic hepatic artery pseudoaneurysm is an uncommon delayed complication of blunt liver trauma. Here we present a case of a 27 year old male with blunt abdominal trauma who developed a post traumatic pseudoaneurysm of the hepatic artery just proximal to its bifurcation into the left and right branches. The pseudoaneurysm ruptured within 12 hours of injury and he required double ligation of the hepatic artery as well as right and left hepatic arteries ...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/29943740/moyamoya-syndrome-in-hemoglobin-e-beta-thalassemia-a-rare-presentation-and-association
#17
P N Doctor, A Choudhari, M Verma, R H Merchant
Moyamoya disease is an idiopathic, nonatherosclerotic, noninflammatory, chronic progressive cerebrovascular disease characterized by bilateral stenosis or occlusion of the arteries around the circle of Willis, typically the supraclinoid internal carotid arteries, followed by extensive collateralization, which are prone to thrombosis, aneurysm, and hemorrhage. Secondary moyamoya phenomenon or moyamoya syndrome (MMS) occurs in a wide range of clinical scenarios including prothrombotic states such as sickle cell anemia, but the association with other hemoglobinopathies is less frequently observed...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/29943738/social-capital-trust-in-health-information-and-acceptance-of-measles-rubella-vaccination-campaign-in-tamil-nadu-a-case-control-study
#18
B Palanisamy, V Gopichandran, K Kosalram
Background: Parents' decision about vaccination of children is influenced by social relationships and sources of information. The aim of this study was to assess the influence of social capital and trust in health information on the status of Measles-Rubella (MR) vaccination campaign in Tamil Nadu. Materials and Methods: This was a case-control study carried out in Kancheepuram district in Tamil Nadu where the MR vaccination campaign offered by Government of Tamil Nadu had poor acceptance...
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/29848835/enzyme-replacement-therapy-in-india-lessons-and-insights
#19
EDITORIAL
M Muranjan, S Karande
No abstract text is available yet for this article.
October 2018: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/30004037/polycystic-ovary-syndrome-pcos-and-kisspeptin-a-sri-lankan-study
#20
B Umayal, S N Jayakody, N V Chandrasekharan, W S S Wijesundera, C N Wijeyaratne
Context: Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder affecting young women. Kisspeptins are a family of closely related peptides encoded by Kiss1 gene that controls the hypothalamic-pituitary-gonadal axis by binding to its receptor (GPR54) expressed in gonadotropin-releasing hormone (GnRH) neurons and releases GnRH. Since GnRH secretion is deregulated in PCOS, we hypothesized that dysregulated gonadotropin secretion in PCOS is reflected by kisspeptin levels. Aim: We aimed to measure serum kisspeptin levels of subjects with well-characterized PCOS versus controls and explore any correlation between kisspeptin and PCOS-related reproductive and metabolic disturbances...
July 13, 2018: Journal of Postgraduate Medicine
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