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Journal of Postgraduate Medicine

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https://www.readbyqxmd.com/read/27853046/imatinib-induced-pleural-effusion-a-case-report
#1
R Banka, Z Udwadia
Imatinib is a tyrosine kinase inhibitor and has rarely been reported to cause pleural effusion. We report the case of an 88-year-old male, known case of gastrointestinal stromal tumor on treatment with imatinib, who presented with a 2-week history of cough and dyspnea. He was diagnosed to have a right-sided pleural effusion and thoracentesis of the fluid revealed an exudate with low adenosine deaminase and negative cytology. Withdrawal of the drug lead to resolution of symptoms. We report this case to highlight the side effect profile of imatinib and warn physicians regarding this potential adverse effect which may be mistaken for metastasis or infection...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27853045/primary-sjogren-s-syndrome-presenting-as-hypokalemic-paralysis-a-case-series
#2
M Goroshi, S Khare, T Jamale, N S Shah
Primary Sjögren's syndrome (pSS) primarily involves exocrine glands, and renal tubular acidosis (RTA) is seen in one-third of the cases. RTA with hypokalemic paralysis as a presenting feature of pSS is described in few case reports in literature. We report 13 cases who presented as hypokalemic paralysis, and on evaluation were diagnosed to be pSS, as per the diagnostic criteria laid by the Sjφgren's International Collaborative Clinical Alliance (2012). All patients were female, with a mean age at presentation being 33...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27853044/ischemic-monomelic-neuropathy
#3
S Sheetal, P Byju, P Manoj
Ischemic monomelic neuropathy is an uncommon complication associated with the creation of arteriovenous (AV) fistula for hemodialysis. After placement of an arteriovenous fistula, there can be shunting of arterial blood away from the distal extremity resulting in damage to distal nerve fibers with acute neurologic symptoms. It can present with global muscle pain, weakness, and a warm hand with palpable pulses starting within the 1 st h after the creation of the AV fistula. It is a devastating complication and can result in permanent disability...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27853043/postradiotherapy-small-cell-neuroendocrine-carcinoma-of-base-of-tongue-an-unusual-clinical-and-site-presentation
#4
V Jha, P Sharma, A K Yadav, A K Mandal
Small cell neuroendocrine carcinoma (NEC) of the tongue is an extremely rare entity with only seven cases reported in literature till date. These are high-grade tumors with a dismal prognosis. There is much ambiguity regarding the classification, treatment protocols and prognostic factors of these tumors due to the paucity of studies. We describe an exceptionally rare and unusual case of small cell NEC of the base of tongue arising in an elderly man 6 years after receiving radiotherapy for the treatment of squamous cell carcinoma at the same site...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27853042/polyarteritis-nodosa-presenting-as-peripheral-vascular-disease-and-acute-limb-ischemia
#5
A Shukla, A Aggarwal
Acute limb ischemia and peripheral vascular disease (PVD) are unusual presentations of polyarteritis nodosa (PAN). Here, we present a case with PVD of both lower limbs leading to foot claudication. Digital subtraction angiography showed narrowing, irregularity, and occlusion of both lower limb arteries with no involvement of the abdomen visceral arteries. Based on significant weight loss, diastolic blood pressure >90 mmHg, myalgia, testicular pain, and angiographic abnormalities in medium-sized arteries, he was diagnosed as having PAN...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27853041/prevalence-and-risk-factors-of-hypertension-and-diabetes-in-the-katkari-tribe-of-coastal-maharashtra
#6
M G Deo, P V Pawar, S R Kanetkar, S V Kakade
BACKGROUND AND OBJECTIVES: Urban and rural India are both going through health epidemiological transition and will soon face huge burden of noncommunicable diseases (NCDs). Information on the status of NCDs in tribals is limited. Although the prevalence of hypertension in scheduled tribes (STs) has been studied in several states by the National Nutrition Monitoring Bureau, tribe-specific data are very scanty. The objective of this study was to generate data on the status of hypertension and diabetes, the two objectively measurable NCDs in Katkaris, the dominant ST in the Raigad district of coastal Maharashtra...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27853040/an-epidemiological-profile-of-chronic-obstructive-pulmonary-disease-a-community-based-study-in-delhi
#7
B Sinha, R Singla, R Chowdhury
BACKGROUND: Different definitions used for chronic obstructive pulmonary disease (COPD) preclude getting reliable prevalence estimates. Study objective was to find the prevalence of COPD as per standard Global Initiative for Chronic Obstructive Lung Disease definition, risk factors associated, and treatment seeking in adults >30 years. METHODOLOGY: Community-based cross-sectional study was conducted in Delhi, among 1200 adults, selected by systematic random sampling...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27853039/pharmacoeconomic-evaluation-of-diabetic-nephropathic-patients-attending-nephrology-department-in-a-tertiary-care-hospital
#8
J V Jose, M Jose, P Devi, R Satish
AIMS: To evaluate the cost of pharmacotherapy and its determinants in diabetic nephropathy (DN) in the nephrology department of a tertiary care hospital. MATERIALS AND METHODS: A prospective observational study was conducted among adult patients visiting nephrology outpatient department (February-July 2015). Data on demography, investigations, and medications prescribed, direct cost and indirect costs were analyzed. We used Chi-squared test for categorical variables and multivariate linear regression analysis to identify determinants of cost of pharmacotherapy and total cost...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27779154/salmonella-pyomyositis-with-concurrent-sacroiliac-osteomyelitis-presenting-as-piriformis-syndrome-a-rare-case
#9
P S Phadke, A R Gandhi, S A More, R P Joshirao
A-21-year old male admitted with fever and piriformis syndrome, typically associated with gluteal region pain radiating down the thigh, was evaluated and found to have pyomyositis involving piriformis and osteomyelitis with sacroiliac joint affection on radiological imaging. Salmonella serotype typhi was isolated from blood culture. He was treated with intravenous Ceftriaxone for 6 weeks with signs of recovery documented clinically as well as on imaging studies. Salmonella pyomyositis with osteomyelitis in an immunocompetent patient with no previous hematological or endocrine disorder makes this case an unusual presentation...
October 24, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27779153/cytohistological-correlation-in-pituitary-tumor-and-immunological-assessment-with-the-help-of-ki-67
#10
A Sen, C Das, M Mukhopadhyay, S Mukhopadhyay, S Deb, B Mukhopadhyay
BACKGROUND: Tumors of the pituitary gland and sellar region represent approximately 10-15% of all brain tumors. Pituitary adenoma (PA), the most common pathology of the pituitary gland, can be effectively subclassified only with the help of immunohistochemistry (IHC). This is important and needed for individual patient management. AIMS AND OBJECTIVES: The objective of the study was to analyze the importance of intraoperative imprint smear cytology and correlating with final histopathological diagnosis...
October 24, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27779152/role-of-demographic-and-job-related-variables-in-determining-work-related-quality-of-life-of-hospital-employees
#11
K Shukla, S Shahane, W D'Souza
BACKGROUND: Considering a huge working population in health sector faced with stressful work life, limited autonomy in work and declining work contentment calls for an overemphasis on evaluating and monitoring their satisfaction associated with work-related quality of life (WRQoL). This study evaluates WRQoL of hospital employees and validates the bilingual (English and Marathi) version of WRQoL scale. METHODS: The study was conducted during March-April'2014 on employees of a corporate hospital of Pune, India after ethical approval and informed consent from employees...
October 24, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652990/evolution-of-medical-education-in-india-the-impact-of-colonialism
#12
A Supe
The cross-cultural exchanges between the people of India and their colonial rulers provides a fascinating insight into how these encounters shaped medicine and medical education in India. This article traces the history of how Indian medicine was transformed in the backdrop of colonialism and hegemony. It goes on to show how six decades after independence, we have have still been unable to convincingly shrug off the colonial yoke. India needs to work out a national medical curriculum which caters to our country's needs...
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652989/maternal-infection-malnutrition-and-low-birth-weight
#13
Manas Pratim Roy
No abstract text is available yet for this article.
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652988/relapsing-remitting-chronic-lymphocytic-inflammation-with-pontine-perivascular-enhancement-responsive-to-steroids-syndrome-in-association-with-p-q-type-voltage-gated-calcium-channel-antibody
#14
D Dubey, M Devine, K Blackburn, W Warnack
No abstract text is available yet for this article.
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652987/right-atrial-mural-thrombi-an-autopsy-study-of-an-under-diagnosed-complication-at-an-unusual-site
#15
P Vaideeswar, J Chaudhari, N Karnik, T Sahu, A Gupta
BACKGROUND: Right atrial mural thrombi (RAMT) are often seen in association with cardiac diseases or foreign bodies. Unusual locations at the flutter isthmus and the atrial appendage prompted us to evaluate our 2-year autopsy data on such thrombi. MATERIALS AND METHODS: In the 2-year retrospective autopsy, the clinical and autopsy records of patients with RAMT were reviewed, with particular reference to the presence of central venous catheter (CVC), its site of insertion, its type, material and size, its duration of placement, and the drugs infused through the catheter...
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652986/adenosine-monophosphate-activated-protein-kinase-based-classification-of-diabetes-pharmacotherapy
#16
D Dutta, S Kalra, M Sharma
The current classification of both diabetes and antidiabetes medication is complex, preventing a treating physician from choosing the most appropriate treatment for an individual patient, sometimes resulting in patient-drug mismatch. We propose a novel, simple systematic classification of drugs, based on their effect on adenosine monophosphate-activated protein kinase (AMPK). AMPK is the master regular of energy metabolism, an energy sensor, activated when cellular energy levels are low, resulting in activation of catabolic process, and inactivation of anabolic process, having a beneficial effect on glycemia in diabetes...
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652985/the-mysterious-zika-virus-adding-to-the-tropical-flavivirus-mayhem
#17
B Mishra, B Behera
Until now, known as the demure cousin of dengue virus (DENV) inhabiting Africa, Zika virus (ZIKV) has reinvented itself to cause explosive epidemics captivating the Western hemisphere. The outbreak causing potential for ZIKV was realized when it made its way from Africa to Yap Island Micronesia in 2007, and in French Polynesia in 2013. From there, it moved on to Brazil in 2015. Now ZIKV has infected people in more than 33 countries in Central and South America and the Caribbean. Moreover the epidemiological and subsequent virological association with microcephaly cases in Brazil has prompted the World Health Organization to declare a public health emergency of International Concern...
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652984/wernicke-s-encephalopathy-due-to-hyperemesis-gravidarum-clinical-and-magnetic-resonance-imaging-characteristics
#18
V V Ashraf, J Prijesh, R Praveenkumar, K Saifudheen
Hyperemesis gravidarum-induced Wernicke's encephalopathy (WE) is an underestimated condition. The purpose of this study is to improve its awareness and early diagnosis. We report five cases of WE secondary to hyperemesis gravidarum. Classic triad of encephalopathy, ataxia, and ocular signs was seen in four out of five patients. Two unusual features noted in this series were papilledema in one patient and severe sensory-motor peripheral neuropathy in one patient. Magnetic resonance imaging (MRI) was abnormal in all the five patients, and high signal in medial thalamus and surrounding the aqueduct was the most common abnormality (5/5)...
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27652983/outcomes-of-a-conservative-approach-to-management-in-amoebic-liver-abscess
#19
S Kale, A J Nanavati, N Borle, S Nagral
CONTEXT: Unfortunately, there is confusion among the medical community regarding the management of amoebic liver abscess (ALA). Therapeutic options range from simple pharmacotherapy to use of interventions like a needle or catheter aspiration under ultrasound guidance to surgical intervention. There is a plethora of thresholds for parameters such as the maximum diameter of the abscess and volume on ultrasound examination suggested by various authors to serve as a criterion to help to decide when to use which modality in these cases...
September 21, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27763490/prevalence-of-burnout-and-its-correlates-among-residents-in-a-tertiary-medical-center-in-kerala-india-a-cross-sectional-study
#20
M D Al-Mendalawi
No abstract text is available yet for this article.
October 2016: Journal of Postgraduate Medicine
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