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Emmanuelle A D Schindler, Douglas A Wright, Marsha J Weil, Christopher H Gottschalk, Brian P Pittman, Jason J Sico
OBJECTIVE: In this secondary analysis of the Clusterbusters® Medication Use survey, the use, effectiveness, and tolerability of inhaled oxygen were investigated and compared with injectable sumatriptan. We also sought to understand the predictors of medication response. BACKGROUND: Inhaled oxygen is a mainstay abortive intervention in cluster headache but is not approved by the Food and Drug Administration (FDA). Unlike injectable sumatriptan, the only FDA-approved pharmacologic intervention for cluster headache, oxygen can be used multiple times a day, which is highly relevant for a condition with numerous daily attacks...
September 17, 2018: Headache
Wietse Wiels, Anissa Ourtani, Anne-Marie Van Binst, Sylvie De Raedt
No abstract text is available yet for this article.
September 17, 2018: Headache
Irina Aschehoug, Daniel Fossum Bratbak, Erling Andreas Tronvik
OBJECTIVES: To investigate long-term outcomes in per-protocol chronic cluster headache patients (n = 7), 18 and 24 months after participation in "Pilot study of sphenopalatine injection of onabotulinumtoxinA for the treatment of intractable chronic cluster headache." METHODS: Data were collected prospectively through headache diaries, HIT-6, and open questionnaire forms at 18 and 24 months after the first treatment. Patients had access to repeated injections when needed...
September 14, 2018: Headache
Mia T Minen, Emma Ortega, Richard B Lipton, Robert Cowan
BACKGROUND: Emergency department (ED) visits for migraine are burdensome to patients and to the larger healthcare system and society. Thus, it is important to determine strategies used to prevent ED visits and the common communication patterns between headache specialists and the ED team. OBJECTIVE: We sought to understand: (1) Whether headache specialists use headache management protocols. (2) The strategies they use to try and reduce the number of ED visits for headache...
September 12, 2018: Headache
Carolyn Bernstein, Jan Shifren, Nasim Maleki
No abstract text is available yet for this article.
September 8, 2018: Headache
Frederick R Taylor
Growth in knowledge about calcitonin gene-related peptide (CGRP) in the pathophysiology of migraine brought CGRP antagonism to headache medicine. Failures in development of small molecule CGRP receptor antagonists and increasing knowledge and use of monoclonal antibodies (mAbs) in medicine led to the breakthrough development of large molecule anti-CGRP mAbs: eptinezumab, erenumab, fremanezumab, and galcanezumab. This specifics about CGRP immunology aims to outline: (1) knowledge needed for CGRP antagonism and (2) developmental issues of specific CGRP antagonists for provider use...
September 5, 2018: Headache
Daniela Vivaldi, Massimiliano Di Giosia, Inna E Tchivileva, Gary W Jay, Gary D Slade, Pei F Lim
Headache attributed to temporomandibular disorders (TMDH) is defined as a secondary headache by the International Classification of Headache Disorders 3rd edition (ICHD-3). OBJECTIVE: The objective of this case-control study is to investigate the phenotypic characteristics of chronic TMD with and without TMDH. We hypothesize that chronic TMD with TMDH is associated with increased number of bodily pain conditions, more painful sites in the head and neck region, and greater TMD pain intensity...
September 4, 2018: Headache
Hidetaka Tamune, Takaie Kuki, Tetsuya Kashiyama, Toshiki Uchihara
OBJECTIVE: -In order to identify appropriate candidates with suspected meningitis for lumbar puncture (LP), study designs and diagnostic values of jolt accentuation of headache (JA) were reviewed. BACKGROUND: -Acute meningitis is a life-threatening disease that requires LP for accurate diagnosis. JA was reported the most sensitive indicator of cerebrospinal fluid pleocytosis; however, subsequent studies have failed to confirm this claim. METHODS: -We reviewed articles concerning JA, published prior to December 2017, using MEDLINE and Japanese medical databases...
September 4, 2018: Headache
Ioana Medrea, Suzanne Christie
OBJECTIVE: The current definition of chronic migraine is relatively new. This definition has been field tested multiple times and has gone through multiple revisions. The evolution of the concept of migraine and its transformation to involve the category of chronic migraine is outlined. DISCUSSION: Chronic migraine as a disease was initially recognized in patients seen in headache clinics with a large burden of disability from frequent headaches and a history of prior migraines...
September 4, 2018: Headache
Valentina Favoni, Luisa Sambati, Federico Oppi, Michelangelo Stanzani Maserati, Sabina Cevoli, Giulia Pierangeli
No abstract text is available yet for this article.
September 3, 2018: Headache
Levi Howard, Gina Dumkrieger, Catherine D Chong, Katherine Ross, Visar Berisha, Todd J Schwedt
BACKGROUND: Most persistent posttraumatic headaches (PPTH) have a phenotype that meets diagnostic criteria for migraine or probable migraine. Although symptoms of autonomic dysfunction have been well described among those with migraine, the presence and relative severity of such symptoms among those with PPTH have yet to be reported. OBJECTIVE: The objective of this study was to assess and compare symptoms of autonomic dysfunction among those with PPTH attributed to mild traumatic brain injury (mTBI) vs migraine vs healthy controls using Composite Autonomic Symptom Score 31 (COMPASS-31) questionnaire scores...
August 29, 2018: Headache
Joshua Lai, Rebecca A Harrison, Alyson Plecash, Thalia S Field
BACKGROUND: Persistent post-stroke headache is a clinical entity that has recently entered the International Classification of Headache Disorders, 3rd edition. In contrast to acute headache attributed to stroke, the epidemiology, clinical features, potential pathophysiology, and management of persistent post-stroke headache have not been reviewed. METHODS: We summarize the literature describing persistent headache attributed to stroke. RESULTS: Persistent headache after ischemic or hemorrhagic stroke affects up to 23% of patients...
August 27, 2018: Headache
Benjamin W Friedman, Sajid Mohamed, Matthew S Robbins, Eddie Irizarry, Valerie Tarsia, Scott Pearlman, E John Gallagher
BACKGROUND: Greater occipital nerve block (GONB) is thought to be an effective treatment for acute migraine, though no randomized efficacy data have been published for this indication. We hypothesized that bilateral GONB with bupivacaine would provide greater rates of headache freedom than a sham injection among a population of emergency department (ED) patients who reported persistence of moderate or severe headache despite standard treatment with intravenous metoclopramide. METHODS: This was a randomized clinical trial conducted in 2 urban EDs...
August 25, 2018: Headache
Todd D Rozen
OBJECTIVE: To determine the efficacy of high-volume anesthetic suboccipital nerve blocks (HVSON) for chronic cluster headache (CCH) and to define consistency of response over long-term use. BACKGROUND: There are studies showing efficacy of greater occipital and suboccipital nerve block injections for CCH and also their possible use as a preventive treatment modality. There are scant data about the long-term efficacy of repetitive greater occipital and suboccipital nerve injections in CCH...
August 24, 2018: Headache
Elizabeth Loder, Paul Rizzoli
This paper describes current non-antibody pharmacologic approaches to the prevention of migraine in adults. Preventive therapy should be considered for patients with migraine who routinely have more than 6 headache days per month or in other special circumstances. Choices for preventive therapy are based on patient preferences about side effects and evidence of efficacy. The evidence level and commonly used doses for selected categories of migraine preventive medication are reviewed, including antiepileptic drugs, antihypertensive drugs, and antidepressants...
August 23, 2018: Headache
Ali G Hamedani, Kailyn F R Witonsky, Mahgenn Cosico, Robert Rennie, Riu Xiao, Claire A Sheldon, Grace L Paley, Shana E McCormack, Geraldine W Liu, Deborah I Friedman, Grant T Liu, Christina L Szperka
Background - Certain headache characteristics and associated symptoms are commonly attributed to increased intracranial pressure, but they have not been systematically studied among children in the context of revised diagnostic criteria for pseudotumor cerebri syndrome (PTCS). Methods - We performed a retrospective cohort study of patients treated for suspected or confirmed PTCS. Charts were reviewed for PTCS and headache diagnostic criteria and associated characteristics. Chi-squared or Fisher's exact tests were used to compare the frequency of headache characteristics between groups...
August 23, 2018: Headache
Ethan Benore, Erin E Webster, Lu Wang, Gerard Banez
BACKGROUND: -Many children suffering from chronic headache and migraine present with comorbid functional disability, including physical, social, emotional, and academic activities. For children severely impaired by headache, intensive interdisciplinary pain rehabilitation treatment (IIPT) can improve functioning. However, there are limited data evaluating children's response to rehabilitation across several time points. OBJECTIVE: -This study aims to evaluate the trajectory of recovery for children undergoing IIPT for chronic headache, as well as to examine the proposed assumption that physical and psychosocial functioning improves prior to a reported reduction in pain...
August 23, 2018: Headache
Rongfei Wang, Ruozhuo Liu, Zhao Dong, Hui Su, Ran Ao, Yinglu Liu, Yan Wang, Lin Ma, Shengyuan Yu
Background - Headache may be due to either a primary or secondary disorder, and neuroimaging assessments can play an important role when differentiating between these types of headache. Although many studies have reported no significant differences between primary headache patients and the general population in terms of abnormal neuroimaging findings, others have shown that neuroimaging may be employed to rule out secondary causes of headache that could impact morbidity and mortality. This issue remains under debate...
August 23, 2018: Headache
Pahn K Choi, Ji Y Chung, Hyun G Kang
No abstract text is available yet for this article.
August 23, 2018: Headache
Yi Zhang, Yuan Chen, Yajun Lian
No abstract text is available yet for this article.
August 21, 2018: Headache
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