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https://www.readbyqxmd.com/read/29762872/the-effect-of-onabotulinumtoxina-on-aura-frequency-and-severity-in-patients-with-hemiplegic-migraine-case-series-of-11-patients
#1
Tiffany Y Chen, Ivan Garza, David W Dodick, Carrie E Robertson
BACKGROUND: OnabotulinumtoxinA has been demonstrated to be effective for the preventive treatment of headache in individuals with chronic migraine and has been approved and recommended for this patient population. While the therapeutic effect of onabotulinumtoxinA on migraine headache is well documented, there is limited information on the effect of onabotulinumtoxinA on migraine aura. OBJECTIVE: Given the prolonged and often debilitating nature of aura in patients with hemiplegic migraine, our group sought to examine the effect of onabotulinumtoxinA on aura frequency and severity in this specific subset of migraine patients...
May 15, 2018: Headache
https://www.readbyqxmd.com/read/29757458/posttraumatic-headache-basic-mechanisms-and-therapeutic-targets
#2
REVIEW
Joshua Kamins, Andrew Charles
Frequent or continuous headache, often refractory to medical therapy, is a common occurrence after head trauma. In addition to being the most common acute symptom after traumatic brain injury (TBI), headache is also one of the most persistent and disabling symptoms. Different studies indicate that 18-58% of those suffering a TBI will have significant headache at 1 year following the trauma. In addition to being disabling on its own, posttraumatic headache (PTH) is a predictor of overall outcome after concussion...
May 14, 2018: Headache
https://www.readbyqxmd.com/read/29737529/posttraumatic-headache-classification-by-symptom-based-clinical-profiles
#3
Sylvia Lucas, Andrew H Ahn
There are currently no accepted therapies for posttraumatic headache (PTH). In order to meet the urgent need for effective therapies for PTH, we must continue to address fundamental gaps in our understanding of the clinical course and impact of PTH. Here we examine the existing schema used to characterize the clinical characteristics of PTH, including the International Classification of Headache Disorders (ICHD). There remain unresolved questions about whether to classify patients based on the extent of brain injury or on clinical symptom profiles...
May 8, 2018: Headache
https://www.readbyqxmd.com/read/29732536/cognitive-behavioral-therapy-for-insomnia-to-reduce-chronic-migraine-a-sequential-bayesian-analysis
#4
REVIEW
Todd A Smitherman, Alexander J Kuka, Anne H Calhoun, A Brooke Pellegrino Walters, Rachel E Davis-Martin, Carrie E Ambrose, Jeanetta C Rains, Timothy T Houle
BACKGROUND: Insomnia is frequently comorbid with chronic migraine, and small trials suggest that cognitive-behavioral treatment of insomnia (CBTi) may reduce migraine frequency. This study endeavored to provide a quantitative synthesis of existing CBTi trials for adults with chronic migraine using Bayesian statistical methods, given their utility in combining prior knowledge with sequentially gathered data. METHODS: Completer analyses of 2 randomized trials comparing CBTi to a sham control intervention (Calhoun and Ford, 2007; Smitherman et al, 2016) were used to quantify the effects of a brief course of treatment on headache frequency...
May 6, 2018: Headache
https://www.readbyqxmd.com/read/29727478/assessing-physician-patient-dialogues-about-chronic-migraine-during-routine-office-visits
#5
Dawn C Buse, Patrick Gillard, Kaitlyn Arctander, Amy W Kuang, Richard B Lipton
OBJECTIVE: To assess physician-patient communication and identify the frequency of use of specific communication techniques by analyzing recordings of routinely scheduled medical encounters for patients with clinician-identified chronic migraine. BACKGROUND: Chronic migraine is an under-diagnosed, under-treated, and highly burdensome disease. Effective medical communication is integral to optimal medical care, including providing accurate diagnoses, creating effective treatment plans, and enhancing patient adherence...
May 4, 2018: Headache
https://www.readbyqxmd.com/read/29727473/can-circadian-dysregulation-exacerbate-migraines
#6
REVIEW
Jason C Ong, Hannah L Taylor, Margaret Park, Helen J Burgess, Rina S Fox, Sarah Snyder, Jeanetta C Rains, Colin A Espie, James K Wyatt
OBJECTIVE: This observational pilot study examined objective circadian phase and sleep timing in chronic migraine (CM) and healthy controls (HC) and the impact of circadian factors on migraine frequency and severity. BACKGROUND: Sleep disturbance has been identified as a risk factor in the development and maintenance of CM but the biological mechanisms linking sleep and migraine remain largely theoretical. METHODS: Twenty women with CM and 20 age-matched HC completed a protocol that included a 7 day sleep assessment at home using wrist actigraphy followed by a circadian phase assessment using salivary melatonin...
May 4, 2018: Headache
https://www.readbyqxmd.com/read/29708585/when-treatment-establishes-diagnosis-a-case-report-of-posttraumatic-chronic-paroxysmal-hemicrania
#7
LETTER
Sneha Jacob, David Watson, Jack E Riggs
No abstract text is available yet for this article.
April 30, 2018: Headache
https://www.readbyqxmd.com/read/29536530/the-use-and-method-of-action-of-intravenous-lidocaine-and-its-metabolite-in-headache-disorders
#8
Thomas Berk, Stephen D Silberstein
BACKGROUND: Lidocaine, an amide anesthetic, has been used in the treatment of a wide variety of pain disorders for over 75 years. In addition to pain control, lidocaine is an anti-arrhythmic agent and has anti-inflammatory properties. Lidocaine's unique properties, including nonlinear pharmacokinetics, have limited its modern-day use. OBJECTIVE: The purpose of this review is to offer a better understanding of the properties of this unique treatment, which we hope will allow more practitioners to offer this to their patients...
March 14, 2018: Headache
https://www.readbyqxmd.com/read/29536529/cluster-headache-clinical-phenotypes-tobacco-nonexposed-never-smoker-and-no-parental-secondary-smoke-exposure-as-a-child-versus-tobacco-exposed-results-from-the-united-states-cluster-headache-survey
#9
Todd D Rozen
OBJECTIVE: To present results from the United States Cluster Headache Survey comparing the clinical presentation of tobacco nonexposed and tobacco-exposed cluster headache patients. BACKGROUND: Cluster headache is uniquely tied to a personal history of tobacco usage/cigarette smoking and, if the individual cluster headache sufferer did not smoke, it has been shown that their parent(s) typically did and that individual had significant secondary smoke exposure as a child...
March 14, 2018: Headache
https://www.readbyqxmd.com/read/29536502/concussion-a-history-of-science-and-medicine-1870-2005
#10
REVIEW
Stephen T Casper
OBJECTIVE: To review the intellectual history of concussion from the mid-19th century to the opening decade of the 21st century. BACKGROUND: Head injuries (HI) and their acute and long-term effects have been investigated for centuries, with major reviews of the topic appearing by 1870. Thus, while it has long been acknowledged that chronic traumatic encephalopathy was first described by Harrison Martland in 1928, an examination of the history of concussion research up to Martland's seminal report places his studies in a deeper historical context...
March 14, 2018: Headache
https://www.readbyqxmd.com/read/29528485/transcranial-magnetic-stimulation-for-migraine-prevention-in-adolescents-a-pilot-open-label-study
#11
Samantha L Irwin, William Qubty, I Elaine Allen, Irene Patniyot, Peter J Goadsby, Amy A Gelfand
OBJECTIVE: To assess the feasibility, tolerability, and patient acceptability of single-pulse transcranial magnetic stimulation (sTMS) for migraine prevention in adolescents in an open-label pilot study. BACKGROUND: Migraine is common in adolescents and can be disabling. Well tolerated preventative therapies that are safe and effective are needed. METHODS: This was an open-label prospective pilot feasibility study of sTMS for migraine prevention in adolescents aged 12-17 years...
March 12, 2018: Headache
https://www.readbyqxmd.com/read/29527677/the-prevalence-and-impact-of-migraine-and-severe-headache-in-the-united-states-figures-and-trends-from-government-health-studies
#12
Rebecca Burch, Paul Rizzoli, Elizabeth Loder
BACKGROUND AND OBJECTIVES: In this targeted systematic review, we aimed to identify up-to-date prevalence estimates of migraine and severe headache in adults from population-based US government surveys. Our goal was to assess the stability of prevalence estimates over time, and to identify additional information pertinent to the burden and treatment of migraine and other severe headache conditions. METHODS: We searched for the most current publicly available summary statistics from the National Health Interview Survey (NHIS), the National Hospital Ambulatory Medical Care Survey (NHAMCS), and the National Ambulatory Medical Care Survey (NAMCS)...
March 12, 2018: Headache
https://www.readbyqxmd.com/read/29520765/factors-associated-with-medication-overuse-headache-in-patients-seeking-treatment-for-primary-headache
#13
Kelly R Peck, Malcolm M Roland, Todd A Smitherman
BACKGROUND: Although risk factors for medication-overuse headache have been identified within the general population, most studies have neglected clinical samples. The present study examined the relative and combined associations of these factors with medication-overuse headache in a sample of US adults seeking treatment for primary headache disorders. METHODS: Treatment-seeking headache patients provided data on demographics, headache variables, psychiatric variables, use of headache medications, and use of other prescription medications and substances...
March 9, 2018: Headache
https://www.readbyqxmd.com/read/29516491/orbital-pain-ophthalmoplegia-and-oligoclonal-bands-in-the-cerebrospinal-fluid-a-case-report-of-tolosa-hunt-syndrome
#14
LETTER
Jonas Alexander Jarholm, Kashif Waqar Faiz, Trond Nysted, Svetozar Zarnovicky, Espen Saxhaug Kristoffersen
No abstract text is available yet for this article.
March 8, 2018: Headache
https://www.readbyqxmd.com/read/29516486/opioid-induced-likeability-and-feeling-good-are-not-associated-with-return-visits-to-an-ed-among-migraine-patients-administered-iv-hydromorphone
#15
Benjamin W Friedman, Alexander Latev, Caron Campbell, Deborah White
BACKGROUND: Parenteral opioids are used in more than 50% of emergency department (ED) visits for migraine. Use of opioids for migraine has been associated with subsequent ED visits, perhaps because of opioid-induced euphoria. In this study, we quantify the extent to which nontherapeutic effects of opioids influence migraine outcomes. We hypothesized that "feeling good" and medication likeability would in fact be associated with receipt of opioids (rather than relief of migraine pain) and that receipt of opioids (rather than relief of migraine pain) would be associated with return visits to the ED...
March 8, 2018: Headache
https://www.readbyqxmd.com/read/29516477/cbt-for-pediatric-migraine-a-qualitative-study-of-patient-and-parent-experience
#16
Ashley M Kroon Van Diest, Michelle M Ernst, Lisa Vaughn, Shalonda Slater, Scott W Powers
OBJECTIVE: The goal of this study was to determine which cognitive behavioral therapy (CBT-HA) treatment components pediatric headache patient stakeholders would report to be most helpful and essential to reducing headache frequency and related disability to develop a streamlined, less burdensome treatment package that would be more accessible to patients and families. BACKGROUND: Pediatric migraine is a prevalent and disabling condition. CBT-HA has been shown to reduce headache frequency and related disability, but may not be readily available or accepted by many migraine sufferers due to treatment burden entailed...
March 8, 2018: Headache
https://www.readbyqxmd.com/read/29488620/mirror-induced-headaches-a-new-self-image-trigger-for-migraine-attacks
#17
Amit Shankar Singh
No abstract text is available yet for this article.
February 28, 2018: Headache
https://www.readbyqxmd.com/read/29476532/research-imaging-of-brain-structure-and-function-after-concussion
#18
REVIEW
Catherine D Chong, Todd J Schwedt
Even when concussions are associated with prolonged physical and cognitive sequelae, concussions are typically "invisible" on diagnostic brain imaging, indicating that the neuropathology associated with concussion lies under the detection threshold of routine imaging. However, data from brain structural and functional research imaging studies using diffusion tensor imaging, resting-state functional magnetic resonance imaging, and brain perfusion imaging indicate that these imaging sequences have a role in identifying concussion-related neuropathology...
February 24, 2018: Headache
https://www.readbyqxmd.com/read/29697156/a-review-of-monoclonal-antibody-therapies-and-other-preventative-treatments-in-migraine
#19
Uwe Reuter
Monoclonal antibodies targeting the calcitonin gene-related peptide pathway represent a new class of mechanism-specific, migraine-targeted therapies available for migraine prevention. To date, four monoclonal antibodies have demonstrated efficacy in phase II and III trials, significantly reducing migraine days per month versus placebo with rapid onset of action. While their efficacy may be considered similar to existing preventive options, their true value may lie in an improved tolerability profile, with high specificity and selectivity for the calcitonin gene-related peptide receptor or ligand reducing the potential for off-target binding and toxicity...
May 2018: Headache
https://www.readbyqxmd.com/read/29697155/foreword-the-cgrp-pathway-and-migraine-prevention-reducing-the-burden-of-disease
#20
Philip R Holland
No abstract text is available yet for this article.
May 2018: Headache
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