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Katherine T Hamilton, Matthew S Robbins
OBJECTIVE: To assess the acute treatment of pregnant women presenting to a hospital with migraine. BACKGROUND: Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population. To date, no study has directly explored physician practices for treatment of acute migraine in pregnant women. METHODS: We conducted a retrospective chart review of medication administration for pregnant women who presented to an acute care setting with a migraine attack and received neurology consultation between 2009 and 2014...
November 7, 2018: Headache
Frederick R Taylor
BACKGROUND: Calcitonin gene-related peptide (CGRP) therapeutics introduce new excitement and possibly yet to be determined distressing discords in the field of Headache Medicine. Growth in knowledge of CGRP in the pathophysiology of migraine introduced CGRP antagonism to headache treatment. Potential adverse effects on the other circulatory and neurovascular diseases have been foremost concerns. Failures in development of gepants and growth in knowledge of monoclonal antibody therapeutics combined to deliver the anti-CGRP monoclonal antibodies (mAbs)...
November 3, 2018: Headache
Dawn C Buse, Jeanetta C Rains, Jelena M Pavlovic, Kristina M Fanning, Michael L Reed, Aubrey Manack Adams, Richard B Lipton
OBJECTIVES: We examined the cross-sectional association of sleep apnea and indices of sleep quality with both episodic migraine (EM) and chronic migraine (CM). BACKGROUND: Sleep apnea and abnormal patterns of sleep, such as insomnia, were associated with migraine onset, severity, and progression in previous research. METHODS: The Chronic Migraine Epidemiology & Outcomes Study, a longitudinal study, used a series of web-based surveys to assess migraine symptoms, burden, and patterns of health care utilization...
November 1, 2018: Headache
Dinesh Lulla, Deniz Altinok, Lalitha Sivaswamy
No abstract text is available yet for this article.
October 31, 2018: Headache
Elizabeth K Seng, Emily D Mauser, Maya Marzouk, Zarine S Patel, Noah Rosen, Dawn C Buse
OBJECTIVE: The current study aimed to describe the impact of parental migraine on adolescent children (aged 11-17) living at home with a parent with migraine. BACKGROUND: Emerging evidence suggests that migraine impacts the family members of people with migraine. However, there has been little research to evaluate the perspective of the child of a parent with migraine. METHODS: This cross-sectional observational study included parents who met International Classification of Headache Disorders criteria for migraine and their 11-17-year-old children currently living with the parent with migraine recruited from neurologist offices and online...
October 31, 2018: Headache
Stephen D Silberstein, Lulu Lee, Kavita Gandhi, Timothy Fitzgerald, Jvawnna Bell, Joshua M Cohen
OBJECTIVE: To examine the disability, health care resource utilization, and direct annual costs among patients with migraine, categorized according to the number of headache days experienced in the past month. BACKGROUND: Migraine exists on a continuum of different attack frequencies and associated levels of disability. People with migraine have increased health care utilization and incur substantially more direct costs than those without the disease. While the broad implications of migraine are evident, there is a need to comprehensively describe the impact of headache frequency on the burden of illness...
October 30, 2018: Headache
Asha Hareendran, Anne Skalicky, Sally Mannix, Sara Lavoie, Pooja Desai, Martha Bayliss, Andrew V Thach, Daniel D Mikol, Dawn C Buse
OBJECTIVE: The objective of this study was to develop a method for evaluating patient-relevant outcomes of interventions for preventing migraine attacks, followed by an assessment of the content validity of a new patient-reported outcome (PRO) instrument: the Migraine Functional Impact Questionnaire (MFIQ). BACKGROUND: The aim of preventive treatments for migraine is not only to reduce migraine frequency, but also to restore patients' ability to function and improve quality of life...
October 30, 2018: Headache
Yuka Matsuzawa, Yuen Shan Christine Lee, Felicia Fraser, Donna Langenbahn, Amanda Shallcross, Scott Powers, Richard Lipton, Naomi Simon, Mia Minen
BACKGROUND/OBJECTIVES: Nonpharmacological interventions, such as biofeedback, cognitive behavioral therapy, and relaxation techniques are Level-A evidence-based treatments for headache. The impact of these interventions is often equivalent to or greater than pharmacological interventions, with fewer side effects. Despite such evidence, the rate of participation in nonpharmacological interventions for headache remains low. Once obstacles to optimizing use of behavioral interventions, such as local access to nonpharmacological treatment and primary headache providers are traversed, identification of barriers contributing to low adherence is imperative given the high levels of disability and cost associated with treating headache disorders...
October 27, 2018: Headache
Elizabeth W Loder, Melissa Rayhill, Rebecca C Burch
OBJECTIVE: We sought to analyze publicly available information about patient harm associated with an iontophoretic sumatriptan patch, to identify what went wrong and to suggest ways in which similar problems might be prevented in the future. BACKGROUND: The Zecuity® sumatriptan iontophoretic transdermal system was marketed for acute treatment of migraine. The patch was withdrawn less than 10 months after its introduction because of multiple reports of scarring and burning...
October 27, 2018: Headache
Verena Sorgenfrei, Peter Kropp, Andreas Straube, Ruth Ruscheweyh
OBJECTIVE: To determine if migraine patients with high achievement motivation have an increased use of acute headache medication. BACKGROUND: It has been hypothesized that high achievement-motivated migraine patients have an increased use of acute headache medication to be able to perform at work and during daily life, putting them at risk for medication overuse headache (MOH). METHODS: The Achievement Motivation Inventory and use of acute headache medication were assessed in 117 migraine patients (60 episodic, 57 chronic) at their first appointment at our tertiary headache center...
October 27, 2018: Headache
Ana Marissa Lagman-Bartolome, Christine Lay
Migraine is a disabling neurological condition and it is well described that early treatment is more effective and less likely to lead to headache recurrence. While it would seem intuitive for a migraine sufferer to treat early, despite well-established guidelines by the Canadian Headache Society, many sufferers continue to treat late. As a result, acute therapy is less effective, resulting in higher associated disability and a longer lasting attack. Pain scales can help patients determine how to treat; however, we propose a simple, easily recalled traffic light system to help patients determine which drug to use based upon how they feel...
October 27, 2018: Headache
Mansoureh Togha, Soodeh Razeghi Jahromi, Zeinab Ghorbani, Fahimeh Martami, Maryam Seifishahpar
OBJECTIVE: The association between serum vitamin D and migraine is investigated in this research.s BACKGROUND: Although the pathogenesis of migraine headache is not fully understood, the possible role of inflammation and disturbed immune system has been proposed; thus, higher levels of vitamin D might reduce the risk of migraine. However, the results of related studies have been inconclusive. METHODS: Seventy healthy individuals and 70 age- and sex-matched migraineurs (34 chronic and 36 episodic migraineurs), diagnosed according to the International Headache Society criteria (ICHD-IIIβ), were recruited...
October 20, 2018: Headache
Bornali Kundu, John D Rolston
OBJECTIVE: The aim of this study was to report the trends in the use of common surgical interventions over the past decade to treat cranial nerve neuralgias. METHODS: The Centers for Medicare and Medicaid Services Part B National Summary Data File from 2000 to 2016 were studied. RESULTS: A total of 57.1 million persons were enrolled in 2016, up from 39.6 million persons in 2000. Suboccipital craniectomy done for cranial nerve decompressions (including cranial nerves V, VII, and IX) increased by 33...
October 18, 2018: Headache
Elizabeth K Seng, Pablo Prieto, Gabriel Boucher, Marina Vives-Mestres
OBJECTIVE: To evaluate factors associated naturalistically with adherence to a mobile headache diary. BACKGROUND: Self-monitoring (keeping a headache diary) is commonly used in headache to enhance diagnostic accuracy and evaluate the effectiveness of headache therapies. Mobile applications are increasingly used to facilitate keeping a headache diary. Little is known about the factors associated with adherence to mobile headache diaries. METHODS: In this naturalistic longitudinal cohort study, people with headache (n = 1561) registered to use Curelator Headache® (now called N1-Headache®), an application that includes a mobile headache diary, through their physician (coupon), or directly through the website or app store using either a paid or free version of the application...
October 18, 2018: Headache
Christina L Szperka, Juliana VanderPluym, Serena L Orr, Christopher B Oakley, William Qubty, Irene Patniyot, Ana Marissa Lagman-Bartolome, Cynthia Morris, Jessica Gautreaux, M Cristina Victorio, Suzanne Hagler, Sona Narula, Meghan S Candee, Catalina Cleves-Bayon, Rashmi Rao, Robert H Fryer, Alma R Bicknese, Marcy Yonker, Andrew D Hershey, Scott W Powers, Peter J Goadsby, Amy A Gelfand
No abstract text is available yet for this article.
October 15, 2018: Headache
Emmanuelle A D Schindler, Douglas A Wright, Marsha J Weil, Christopher H Gottschalk, Brian P Pittman, Jason J Sico
OBJECTIVE: In this secondary analysis of the Clusterbusters® Medication Use survey, the use, effectiveness, and tolerability of inhaled oxygen were investigated and compared with injectable sumatriptan. We also sought to understand the predictors of medication response. BACKGROUND: Inhaled oxygen is a mainstay abortive intervention in cluster headache but is not approved by the Food and Drug Administration (FDA). Unlike injectable sumatriptan, the only FDA-approved pharmacologic intervention for cluster headache, oxygen can be used multiple times a day, which is highly relevant for a condition with numerous daily attacks...
September 17, 2018: Headache
Wietse Wiels, Anissa Ourtani, Anne-Marie Van Binst, Sylvie De Raedt
No abstract text is available yet for this article.
September 17, 2018: Headache
Irina Aschehoug, Daniel Fossum Bratbak, Erling Andreas Tronvik
OBJECTIVES: To investigate long-term outcomes in per-protocol chronic cluster headache patients (n = 7), 18 and 24 months after participation in "Pilot study of sphenopalatine injection of onabotulinumtoxinA for the treatment of intractable chronic cluster headache." METHODS: Data were collected prospectively through headache diaries, HIT-6, and open questionnaire forms at 18 and 24 months after the first treatment. Patients had access to repeated injections when needed...
September 14, 2018: Headache
Carolyn Bernstein, Jan Shifren, Nasim Maleki
No abstract text is available yet for this article.
September 8, 2018: Headache
Daniela Vivaldi, Massimiliano Di Giosia, Inna E Tchivileva, Gary W Jay, Gary D Slade, Pei F Lim
Headache attributed to temporomandibular disorders (TMDH) is defined as a secondary headache by the International Classification of Headache Disorders 3rd edition (ICHD-3). OBJECTIVE: The objective of this case-control study is to investigate the phenotypic characteristics of chronic TMD with and without TMDH. We hypothesize that chronic TMD with TMDH is associated with increased number of bodily pain conditions, more painful sites in the head and neck region, and greater TMD pain intensity...
September 4, 2018: Headache
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