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Indian Pediatrics

Tarun Gera, Dheeraj Shah, Harshpal Singh Sachdev
OBJECTIVE: To evaluate the impact of water, sanitation and hygiene (WASH) interventions in children (age <18 y) on growth, non-diarrheal morbidity and mortality in children. DESIGN: Systematic review of randomized controlled trials, non-randomized controlled trials and controlled before-after studies. SETTING: Low- and middle-income countries. PARTICIPANTS: 41 trials with WASH intervention, incorporating data on 113055 children...
February 9, 2018: Indian Pediatrics
Pankaj Yadav, Pankaj Sharma, Rohit Arora
We carried out content analysis of 4 batches each of 3 commercially available probiotic formulations proposed to be containing Bacillus clausii. Species identification was done using MALDI-TOF-MS technique while bacterial count was done using plate colony count. Only one of the three probiotic formulation analyzed was found to have homogeneous population of B. clausii while none was found to have the exact viable bacterial count as suggested on the label.
February 9, 2018: Indian Pediatrics
Mini Sreedharan, Kalpana Devadathan, Kunju P A Mohammed, Bindusha Sasidharan, Jayakumar Parameswaran Pillai, Minikumari Amma Vasumathy Amma, Saboorabeegum Muthubeevi
OBJECTIVE: To assess the effect of monotherapy with Carbamazepine (CBZ) and Sodium valproate (VPA) on serum 25-OH Vitamin D levels in children with epilepsy compared to controls. DESIGN: Cross-sectional study. SETTING: Outpatient department of a tertiary-care Pediatric Neurology centre, and a nearby day-care centre and school. STUDY PERIOD: June 2012 to May 2013. PARTICIPANTS: Children with epilepsy aged 2 to 13 years on monotherapy with CBZ (n=28) or VPA (n=28) for at least 6 months; 109 age-matched controls from a nearby day-care centre and school...
February 9, 2018: Indian Pediatrics
P Hansashree, Sanjay Verma, Amit Rawat, Naveen Sankhyan, Bhavneet Bharti
OBJECTIVE: To find out seropositivity rates at 4-6 and 9-12 years of age; among those who received one-dose measles at 9 months and one-dose MMR at 15 months of age. METHODS: 80 healthy children (53 males) at 4-6 or 9-12 years of age, attending outpatient department for vaccination were enrolled. Antibody titers were estimated using commercially available quantitative-IgG ELISA kits. RESULTS: The seropositivity rates against measles, mumps, rubella were 80% (40/50), 86% (43/50), and 96% (48/50), respectively at 4-6 years, and 83...
February 9, 2018: Indian Pediatrics
Meenakshi Lallar, Archana Rai, Priyanka Srivastava, Kausik Mandal, Neerja Gupta, Madhulika Kabra, Shubha R Phadke
OBJECTIVE: To assess yield of MECP2 gene sequence variations analysis and large deletions in suspected cases of Rett syndrome. DESIGN: Descriptive study. SETTING: Tertiary-care medical genetics center. PATIENTS: Girls with neuroregression, postnatal microcephaly and signs and symptoms suggestive of classical and atypical Rett syndrome were classified into two groups. Group I consisted of girls with Classical and atypical Rett syndrome on basis on the Revised Rett Syndrome diagnostic criteria, 2010...
February 9, 2018: Indian Pediatrics
Vivek V Shukla, Satvik Bansal, Archana Nimbalkar, Apurva Chapla, Ajay Phatak, Dipen Patel, Somashekhar Nimbalkar
OBJECTIVE: To compare individual efficacy and additive effects of pain control interventions in preterm neonates. DESIGN: Randomized controlled trial. SETTING: Level-3 University affiliated neonatal intensive care unit. PARTICIPANTS: 200 neonates (26-36 weeks gestational age) requiring heel-stick for bedside glucose assessment. Exclusion criteria were neurologic impairment and critical illness precluding study interventions...
February 9, 2018: Indian Pediatrics
Mullai Baalaaji, Muralidharan Jayashree, Karthi Nallasamy, Sunit Singhi, Arun Bansal
OBJECTIVE: To identify predictors and outcome of acute kidney injury (AKI) in children with diabetic ketoacidosis (DKA) admitted to a Pediatric Intensive Care Unit (PICU). METHODS: Retrospective case review of 79 children with DKA admitted between 2011-2014. RESULTS: Twenty eight children developed AKI during the hospital stay; 20 (71.4%) recovered with hydration alone. Serum chloride at 24 hours was independently associated with AKI. Children with AKI had prolonged acidosis and PICU stay and higher mortality...
February 9, 2018: Indian Pediatrics
B Vamshi Krishna, Suman Das, Sandip Sen
OBJECTIVE: To determine the correlation and validity of non-invasive blood pressure obtained by auscultatory and oscillometric methods compared to invasive blood pressure in critically ill children. METHODS: We compared invasive with auscultatory and oscillometric blood pressures using paired t-test, Pearson's correlation coefficient and Bland-Altman plot in 50 children (age 1-12 y) admitted in Pediatric intensive care unit. RESULTS: Systolic, diastolic, and mean arterial pressures of invasive methods significantly correlated with auscultatory and oscillometric methods (P<0...
February 9, 2018: Indian Pediatrics
Smita Nair, Amitabh Singh, Mamta Jajoo
This retrospective observational study aimed to find the clinical profile of hypernatremic dehydration in neonates. 49 neonates (3.4% of the total admitted newborns) developed hypernatremic dehydration. The major presenting complaints were fever (34.6%), poor feeding (42.8%), loose stools (40.8%) and lethargy (26.5%). The time needed for correction of hypernatremia was 38.6 (±15.1) hours. Exclusively breastfed neonates had lesser complication rates of hypernatremic dehydration.
February 9, 2018: Indian Pediatrics
Anitha Abimannane, Ramachandran Rameshkumar, Ponnarmeni Satheesh, Subramanian Mahadevan
OBJECTIVE: To study the effect of the second dose of scorpion antivenom in children with non-resolving or worsening scorpion sting envenomation. METHODS: 72 children aged ≤12 years with scorpion sting envenomation grade 2 and above were enrolled. 61 received the first dose of three vials of antivenom at admission (group A). Children with persistent/worsening envenomation at 6 hours received the second dose (group B). The time required for resolution of autonomic symptoms, myocardial dysfunction, predictors of the second dose and side effects were studied...
February 9, 2018: Indian Pediatrics
Surbhi V Gupta, Anju Aggarwal, M M A Faridi, Gargi Rai, Shukla Das, Mrinalini Kotru
OBJECTIVE: To compare levels of IL-6 in children with febrile seizures and febrile controls. METHODS: Study conducted in a tertiary-care hospital in Northern India from November 2013 to April 2015, enrolling 160 children (80 each with febrile seizures and febrile controls), aged6 months - 60 months. Serum IL-6 estimated by ELISA method. Iron study done as per standard technique. All the cases of febrile seizure were followed up at 1 week, 3 months and 6 months for recurrence of seizures...
February 9, 2018: Indian Pediatrics
Chandrika Verma, M M A Faridi, Manish Narang, Iqbal R Kaur
OBJECTIVE: To compare anti HBs titers between term low birth weight (1800-2499 g) infants and normal birth weight infants, 6 weeks after last dose of primary immunization with pentavalent vaccine, and to study adverse events following immunization (AEFI) with pentavalent vaccine. DESIGN: Cohort study. SETTING: Tertiary-care hospital predominantly catering to urban poor population of East Delhi. PARTICIPANTS: 265 low birth weight (1800-2499 g) and 265 normal birth weight (2500-4000 g) infants Monovalent Hepatitis B vaccine was administered within 24 hours of birth followed by three primary doses of pentavalent vaccine at 6, 10 and 14 weeks...
February 9, 2018: Indian Pediatrics
Ugra Mohan Jha, Neeraj Dhingra, Yujwal Raj Jones, Bharat Bhusan Rewari, L Jeyaseelan, Pauline Harvey, Laxmikant Chavan, Niranjan Saggurti, D C S Reddy
OBJECTIVE: To assess the survival probability and associated factors among children living with human immunodeficiency virus (CLHIV) receiving antiretroviral therapy (ART) in India. METHODS: The data on 5874 children (55% boys) from one of the high HIV burden states of India from the cohort were analyzed. Data were extracted from the computerized management information system of the National AIDS Control Organization (NACO). Children were eligible for inclusion if they had started ART during 2007-2013, and had at least one potential follow-up...
February 9, 2018: Indian Pediatrics
Sunita V S Bandewar, Amita Aggarwal, Rajeev Kumar, Rakesh Aggarwal, Peush C Sahni, Sanjay A Pai
No abstract text is available yet for this article.
December 29, 2017: Indian Pediatrics
Jogender Kumar, Amitabh Singh
No abstract text is available yet for this article.
February 15, 2018: Indian Pediatrics
Rajiv Sinha, Nayan Banerji, Subhasis Saha
No abstract text is available yet for this article.
February 15, 2018: Indian Pediatrics
Prashant Patil, Dinesh Giri, Mohammed Didi, Senthil Senniappan
Congenital Hyperinsulinism (CHI) is a major cause of neonatal hypoglycemia characterised by non-ketotic hypoglycemia. We describe the occurrence and higher prevalence of ketotic hypoglycemia (KH) in 5 children with transient CHI. Four children had required diazoxide to control the persistent hypoglycemia that was discontinued at a mean age of 11.25 (+5.25) months. KH developed after an average time period of 6.7 months following the resolution of CHI. Children with transient CHI may be at risk of subsequently developing KH at a variable age period...
February 15, 2018: Indian Pediatrics
Thananda Trakarnvanich, Supatsri Sethasine, Charnarong Trisuwanwat, Methavee Insawang
We studied two types of formative assessment: recall type, and problem-based questions, with summative scores and previous grades in 77 fourth-year medical students. We found that the formative scores did not correlate well with the summative scores, but were associated with the Grade point average in the preclinical period.
February 15, 2018: Indian Pediatrics
Almudena Alonso-Ojembarrena, Antonio Segado-Arenas, Isabel Benavente-Fernández, Simón Pedro Lubián-López
We describe our experience with helmet-delivered continuous positive airway pressure in five preterm newborns. We analyzed oxygen requirement, arterial oxygen saturation, respiratory rate, medium arterial pressure, heart rate, apneic spells and patient's comfort. The patients' vital signs or pain scale were not different before and after treatment.
February 15, 2018: Indian Pediatrics
Siva Prasad Vyasam, Thangaraj Abiramalatha, Nalapalu Srinivasan Hema, Niranjan Thomas
BACKGROUND: Cytomegalovirus (CMV) enterocolitis is rare in term neonates. CASE CHARACTERISTICS: A term newborn with persistent pneumonia from birth developed enterocolitis on day 18 of life. OUTCOME: Polymerase chain reaction (PCR) for CMV DNA was positive in urine sample. Antiviral therapy for six weeks resulted in successful treatment without any stricture formation. MESSAGE: CMV enterocolitis should be considered as a differential diagnosis in atypical cases of necrotizing enterocolitis in neonates...
February 15, 2018: Indian Pediatrics
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