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Folia Medica

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https://www.readbyqxmd.com/read/29668462/electrodermal-activity-monitoring-during-endotracheal-suction-in-sedated-adult-intensive-care-unit-patients
#1
Theodoros Aslanidis, Vasilios Grosomanidis, Konstantinos Karakoulas, Athanasios Chatzisotiriou
BACKGROUND: Endotracheal suctioning of respiratory secretions is one of the most common causes of pain and discomfort in Intensive Care Unit environment. The electrical properties of the skin, also known as electrodermal activity (EDA), are considered as an indirect measure of autonomous nervous system. AIM: This study explores EDA changes during endotracheal suction in sedated adult critical care patients; and compares these changes to other monitoring parameters...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668461/mobilization-and-stimulation-of-neuromuscular-tissue-masont-for-stroke-survivors
#2
Dimitrios Athanasiadis, Yannis Dionyssiotis, Jannis Papathanasiou, Eleftherios Stefas
Mobilization and Stimulation of Neuromuscular Tissue (MASONT) is a newly invented somatosensory intervention used for the recovery of function in stroke patients. This paper aims to offer a more spherical view on the new technique. To that end, a basic manual of MASONT's application is provided, along with its rational of use. Moreover, clinical observations on the application of the technique and its effects on neurological patients are presented, as well as, a report on its safety.
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668460/relations-of-apelin-with-cardiac-remodeling-in-patients-with-hypertension-and-type-2-diabetes
#3
Sergiy Koval, Kostiantyn Iushko, Tatyana Starchenko
BACKGROUND: The peptide apelin has antihypertensive and antidiabetic properties, but its role in the processes of cardiac remodeling in patients with hypertension and type 2 diabetes (T2D) is poorly understood. AIM: The aim of the study was to investigate apelin levels in patients with hyper-tension and T2D and to determine its relations to heart structural parameters and types of cardiac remodeling. MATERIALS AND METHODS: We examined 63 patients with hypertension and T2D...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668459/mucocele-of-the-paranasal-sinuses-retrospective-analysis-of-a-series-of-seven-cases
#4
Karen B Dzhambazov, Borislav D Kitov, Hristo B Zhelyazkov, Nikoleta I Traykova, Ivo I Kehayov, Tanya T Kitova
AIM: The present study aimed at identifying the risk factors, typical clinical symptoms and applied treatment in seven cases with mucocele of the paranasal sinuses. MATERIALS AND METHODS: Seven patients suffering from mucocele of the paranasal sinuses were admitted to the Clinic of Neurosurgery and the Clinic of Ear, Nose and Throat Diseases between 2014 and 2016. There were 4 females and 3 males aged between 22 and 78 (95% CI [31.44, 70.23]). Initial symptoms, their duration, clinical presentation upon admission, localization of the mucocele, type of surgical intervention and outcome have all been studied...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668458/on-the-concepts-and-history-of-glioblastoma-multiforme-morphology-genetics-and-epigenetics
#5
REVIEW
George St Stoyanov, Deyan L Dzhenkov
Glioblastoma multiforme (GBM) is a grade IV WHO malignant tumor with astrocytic differentiation. As one of the most common clinically diagnosed central nervous system (CNS) oncological entries, there have been a wide variety of historical reports of the description and evolution of ideas regarding these tumors. The first recorded reports of gliomas were given in British scientific reports, by Berns in 1800 and in 1804 by Abernety, with the first comprehensive histomorphological description being given in 1865 by Rudolf Virchow...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668457/probiotics-evidence-of-oral-health-implications
#6
REVIEW
Jukka H Meurman, Iva V Stamatova
The prevalence of common oral diseases, such as dental caries, periodontal diseases and oral candidiasis remains high in the general population. Various preventive strategies have been proposed and included in national health programs promoting oral health. Interest in probiotics in light of oral health has gradually evolved as attractive means in prevention of oral infectious diseases. The aim of the present review is to outline the current evidence on the role of probiotic species on oral health parameters and their beneficial role in contributing to healthier oral environment...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668456/review-on-retinal-gliosis-illustrated-with-a-series-of-massive-glioses-and-focal-nodular-gliosis-cases-in-regard-to-potential-pitfalls-of-ocular-reactive-tumor-like-lesions-of-this-type
#7
REVIEW
Andrzej Wincewicz, Sławka Urbaniak-Wasik, Antoinette Urbaniak, Marlena Mościcka-Rylska, Martyna Woltanowska, Mariusz Koda, Stanislaw Sulkowski, Joanna Reszeć
This paper presents a review on retinal gliosis illustrated by series of three cases of patients (a 39-year-old man and a 35-year-old woman with massive retinal gliosis (MRG) and a 51-year-old man with truly focal nodular gliosis of retina) with intraocular tumor-like masses and loss of vision, who recently suffered from painful inflammation of eyeball and who classically had a history of remote ocular trauma, onset of blindness early in lifetime or gradual but progressive loss of sight. The diagnosis of this pathological entity is given for the lesions that are composed of GFAP strongly positive, elongated, fusiform cells consistent with fibrillary astrocytes...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668455/lateral-cephalometric-study-in-adult-bulgarians-with-normal-occlusion
#8
Katya G Todorova-Plachiyska, Mariya G Stoilova-Todorova
Orthodontic treatment is effective when the facial and cephalometric characteristics of the ethnic background of patients are considered because the normal measurements for one group are not necessarily normal for another group. It is important to develop individual standards for each population. Different racial groups must be treated according to their own characteristics. The aim of this study was to establish a cephalometric standard of the cranial bases and jaw bases for Bulgarian population and to find the differences between males and females...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668454/identification-of-the-external-branch-of-the-superior-laryngeal-nerve-during-thyroid-surgery
#9
Lyubka Aleksova, Metin M Ali, Djevdet I Chakarov, Zeynep M Yozgyur
AIM: To compare the level of intra-operative identification of external branch of the superior laryngeal nerve (EBSLN) through classical conventional clinical methods of prevention against those applying intraoperative neuromonitoring (IONM). MATERIALS AND METHODS: The study included 102 patients with interventions on the thyroid gland performed in the surgical clinics of St George University Hospital and the Department of Special Surgery of Plovdiv Medical University...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668453/the-skin-and-the-eye-herpes-zoster-ophthalmicus-in-a-healthy-18-month-old-toddler
#10
Radka T Komitova, Oliana B Boykinova, Nina S Stoyanova
Herpes zoster, caused by reactivation of varicella-zoster virus, is uncommon in infancy. Even more uncommon is herpes zoster ophthalmicus, defined as herpes zoster of the ophthalmic branch of the fifth cranial nerve. Among healthy children, primary varicella-zoster virus infection during gestation as a result of maternal varicella or the first year of life is the major risk factor for development of herpes zoster in a relatively young age. Here we present an unusual case of herpes zoster ophthalmicus with dissemination in an immunocompetent toddler with favorable outcome...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668452/can-wearable-devices-accurately-measure-heart-rate-variability-a-systematic-review
#11
REVIEW
Konstantinos Georgiou, Andreas V Larentzakis, Nehal N Khamis, Ghadah I Alsuhaibani, Yasser A Alaska, Elias J Giallafos
BACKGROUND: A growing number of wearable devices claim to provide accurate, cheap and easily applicable heart rate variability (HRV) indices. This is mainly accomplished by using wearable photoplethysmography (PPG) and/or electrocardiography (ECG), through simple and non-invasive techniques, as a substitute of the gold standard RR interval estimation through electrocardiogram. Although the agreement between pulse rate variability (PRV) and HRV has been evaluated in the literature, the reported results are still inconclusive especially when using wearable devices...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668451/a-review-on-dna-repair-inhibition-by-parp-inhibitors-in-cancer-therapy
#12
REVIEW
Ashish P Shah, Chhagan N Patel, Dipen K Sureja, Kirtan P Sanghavi
The DNA repair process protects the cells from DNA damaging agent by multiple pathways. Majority of the cancer therapy cause DNA damage which leads to apoptosis. The cell has natural ability to repair this damage which ultimately leads to development of resistance of drugs. The key enzymes involved in DNA repair process are poly(ADP-ribose) (PAR) and poly(ADP-ribose) polymerases (PARP). Tumor cells repair their defective gene via defective homologues recombination (HR) in the presence of enzyme PARP. PARP inhibitors inhibit the enzyme poly(ADP-ribose) polymerases (PARPs) which lead to apoptosis of cancer cells...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668450/comorbidities-of-copd-in-bulgarian-patients-prevalence-and-association-with-severity-and-inflammation
#13
Velin Stratev, Diana Petkova, Valentina Dimitrova, Jordan Petev
BACKGROUND: wis a disease with constantly rising economic and social burden; it is associated with multiple comorbidities which contribute to the disease severity. AIM: To investigate the prevalence of co-morbidities in COPD patients and their association with the disease severity and CRP levels. PATIENTS AND METHODS: We conducted a retrospective study among 338 COPD patients (mean age 65.2±7.6 years) with assessment of comorbidities, spirometry measurements and serum levels of CRP...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668449/budgetary-impact-of-medicinal-therapies-for-rare-diseases-in-bulgaria
#14
Georgi G Iskrov, Mihajlo Michael Jakovljevic, Rumen S Stefanov
BACKGROUND: Rare diseases have been continually outlined as one of the causes for the National Health Insurance Fund's (NHIF) deficit spending in Bulgaria. AIM: To estimate the budgetary impact of rare disease medicinal therapies from NHIF perspective for 2014 and 2016. MATERIALS AND METHODS: Budgetary impact of rare diseases is calculated as a percentage of NHIF total pharmaceutical spending. Total expenditure per ICD-10 code, mean annual number of patients reimbursed and mean annual cost per patient are analysed...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668448/tranexamic-acid-in-pertrochanteric-femoral-fracture-is-it-a-safe-drug-or-not
#15
Andrea Schiavone, Michele Bisaccia, Ivan Inkov, Giuseppe Rinonapoli, Mattia Manni, Giuseppe Rollo, Luigi Meccariello, Cristina Ibáñez Vicente, Paolo Ceccarini, Carmelinda Ruggiero, Auro Caraffa
BACKGROUND: There is a high incidence of blood transfusion following hip fractures in elderly patients. AIM: The aim of this study is to evaluate the effectiveness and complications of use of tranexamic acid in proximal femur nailing surgery. MATERIALS AND METHODS: Our sample group consisted of 90 patients suffering from pertrochanteric fractures surgically treated with osteosynthesis with SupernailGT(LimaCorporate). The classification system AO/OTA was used to divide the fractures into 31A1 (n=45) and 31A2 (n=45)...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668447/diagnosis-and-treatment-of-three-cases-of-bronchial-carcinoma-in-situ
#16
Valeri Y Andreev, Nikolay A Yanev, Stefan K Stanimirov, Temenuzhka V Mircheva, Ivan N Ivanov, Savelina Popovska, Petkana A Hristova, Yavor Y Ivanov
As part of a retrospective study on bronchoscopies performed at the Clinic of Pneumonology and Phthisiatry of the University Hospital - Pleven by autofluorescence bronchoscopy we found 3 cases diagnosed with carcinoma in situ. They were treated in different ways - endobronchial electrocoagulation, extraction by forceps biopsy and open surgery, but the result was the same - clinical healing. The paper presents the three clinical cases and the analysis of the treatment.
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668446/antidepressant-effect-and-recognition-memory-improvement-of-two-novel-plant-extract-combinations-antistress-i-and-anti-stress-ii-on-rats-subjected-to-a-model-of-mild-chronic-stress
#17
Ilin K Kandilarov, Hristina I Zlatanova, Maria T Georgieva-Kotetarova, Ivanka I Kostadinova, Mariana N Katsarova, Stela Z Dimitrova, Ludmil K Lukanov, Ferit Sadakov
BACKGROUND: Chronic stress is one of the main factors which lead to depression - a psychiatric disorder affecting millions of people and predicted to be the second ranked cause of premature death in 2020. Depression is often associated with cognitive disturbances and memory deficit. Plant based therapy could be effective in the treatment of mild to moderate depression due to its low level of adverse reaction, its good tolerability and compliance. MATERIALS AND METHODS: 72 male Wistar rats, divided in 9 groups were given orally for 8 weeks two combinations of dry plant extracts - Antistress I and Antistress II and five individual dry extracts obtained from Serratula coronata, Hypericum perforatum, Valeriana officinalis, Crataegus monogyna and Melissa officinalis...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668445/pathobiochemical-mechanisms-relating-iron-homeostasis-with-parameters-of-inflammatory-activity-and-autoimmune-disorders-in-rheumatoid-arthritis
#18
Katya I Stefanova, Ginka T Delcheva, Ana I Maneva, Anastas Z Batalov, Mariela G Geneva-Popova, Rositza V Karalilova, Kiril K Simitchiev
AIM: To find the correlations between the parameters of iron homeostasis, inflammatory activity and autoimmune disorders in rheumatoid arthritis (RA). MATERIALS AND METHODS: The present study included 114 patients with RA and 42 healthy controls. We determined the parameters of iron homeostasis: serum iron, total iron binding capacity (TIBC), ferritin and soluble transferrin receptor (sTfR), the parameters of inflammatory activity: C-reactive protein (CRP), interleukin-6 (IL-6) and prohepcidin, and the parameters of autoimmune disorders: rheumatoid factor (RF), anti-cyclic citrullinated peptide (antiCCP) antibodies and DAS 28...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668444/oblong-sesamoid-bone-appearance-into-the-nuchal-ligament-a-case-report
#19
Themistoklis Tzatzairis, Jannis V Papathanasiou, Athanasios Ververidis, Ioannis Kazakos, Georgios Drosos, Konstantinos Tilkeridis
Radio-opaque formations behind the spinous processes of the cervical spine are really rare. They were described in 1929 for the first time. Sesamoid ossicles are found close to a bone or a joint and are usually small. Some sesamoids form part of normal human anatomy, while others are normal anatomical variants. We report a case of a 73-year-old Caucasian male who visited the outpatient clinic complaining about chronic cervical pain. An oblong sesamoid accidentally discovered during routine anteroposterior (AP) and lateral x-ray, within the nuchal ligament (NL) at the C3-C6 spinous processes level...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668443/development-and-validation-of-hplc-analytical-method-for-chlorantraniliprole-in-bulk-and-in-the-formulation
#20
Pankaj P Kapupara, Vandana Sorathiya, Ravi P Patel, Ketan V Shah
BACKGROUND: Chlorantraniliprole is widely used as a pesticide. It is only soluble in dimethyl formamide. However, most of the reported methods used acetonitrile and other solvents. AIM: To develop rapid, accurate, precise, and sensitive HPLC method for chlorantraniliprole. MATERIALS AND METHODS: 10 μG/mL of chlorantraniliprole containing solution was injected into the HPLC system and run in different solvent systems. 10 μG/mL solutions of chlorantraniprole was injected in a column with 20 μL microsyringe...
March 1, 2018: Folia Medica
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