journal
MENU ▼
Read by QxMD icon Read
search

Clinica Chimica Acta; International Journal of Clinical Chemistry

journal
https://www.readbyqxmd.com/read/29684383/prognostic-role-of-haematological-indices-in-sudden-sensorineural-hearing-loss-review-and-meta-analysis
#1
REVIEW
Zaizai Cao, Ziyue Li, Haijie Xiang, Saiyu Huang, Jinjian Gao, Xiang Zhan, Xiuxiu Zhen, Bangliang Li, JianBin Wu, Bobei Chen
BACKGROUND: Complete blood count (CBC) is an important blood test in clinical practice, and it has been recently used to predict the prognosis of patients with sudden sensorineural hearing loss (SSNHL). Some haematological indices of the CBC test have been reported to be associated with the clinical outcome of SSNHL. However, the prognostic value of these haematological indices in SSNHL is currently under debate. Here, we performed a meta-analysis to investigate the association between haematological indices of the CBC test and clinical outcomes in patients with SSNHL...
April 20, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29684382/maternal-plasma-concentrations-of-macrophage-migration-inhibitory-factor-at-first-trimester-as-a-predictive-biomarker-of-preterm-delivery-in-chinese-women
#2
Hui Zhu, Mei-Jun Yang
BACKGROUND: Infection and/or inflammation have been proposed play role in the preterm delivery (PTD) pathogenesis. Macrophage migration inhibitory factor(MIF), a mediator of innate immunity and inflammation, is induced in various infections, including those that occur during pregnancy. We assessed the relation between maternal early pregnancy plasma concentrations of MIF and PTD. METHODS: Women were recruited before 14 weeks gestation and were followed up until delivery...
April 20, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29684381/serum-chloride-as-a-novel-marker-for-adding-prognostic-information-of-mortality-in-chronic-heart-failure
#3
Yang Zhang, Rui Peng, Xinqiang Li, Jinxing Yu, Xi Chen, Zhou Zhou
BACKGROUND: Serum chloride concentrations have clinical significance in the prognosis of heart failure (HF). Little is known regarding the prognostic value of serum chloride in patients with chronic heart failure (CHF). This study sought to investigate the prognostic ability of admission serum chloride for long-term mortality in CHF patients. METHODS: We recruited 1021 patients diagnosed with CHF. Participants were followed up for all-cause mortality at 21 ± 9 months to establish the survival models and analyze the association between admission serum chloride concentrations and death risk...
April 20, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29684380/sustained-or-higher-levels-of-growth-factors-in-platelet-rich-plasma-during-7-day-storage
#4
Ying-Hao Wen, Wan-Ying Lin, Chi-Jui Lin, Yu-Chen Sun, Pi-Yueh Chang, Hsin-Yao Wang, Jang-Jih Lu, Wen-Lin Yeh, Tzong-Shi Chiueh
BACKGROUND: The effectiveness of platelet-rich plasma (PRP) for treating soft tissue injuries is still controversial. Most of PRPs were prepared simply by concentrating in volume and were injected right after preparation in physician offices. Neither platelet count nor growth factors were quantitated in advance. We prepared and stored leukocyte and platelet-rich plasma (L-PRP) by regular separation protocols for blood components in the blood bank. And we investigated the dynamic change of growth factors in the L-PRPs over the period of storage...
April 20, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29680229/zap-70-in-chronic-lymphocytic-leukemia-a-meta-analysis
#5
REVIEW
Yini Liu, Yangfeng Wang, Jule Yang, Yongyi Bi, Hong Wang
BACKGROUND: Recent studies have reported that zeta-chain-associated protein kinase 70 (ZAP-70) expression plays a prognostic role in chronic lymphocytic leukemia (CLL). However, these results remain controversial. Thus, we performed a meta-analysis to clarify the prognostic value of ZAP-70 expression in CLL. MATERIALS AND METHODS: Relevant studies were searched in PubMed, Embase, Cochrane library, and Web of Science up to January 2018. Clinicopathological features and prognostic data were extracted from the studies...
April 19, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29678632/mass-spectrometry-based-metabolomics-for-tuberculosis-meningitis
#6
REVIEW
Peixu Zhang, Weiguanliu Zhang, Yue Lang, Yan Qu, Fengna Chu, Jiafeng Chen, Li Cui
Tuberculosis meningitis (TBM) is a prevalent form of extra-pulmonary tuberculosis that causes substantial morbidity and mortality. Diagnosis of TBM is difficult because of the limited sensitivity of existing laboratory techniques. A metabolomics approach can be used to investigate the sets of metabolites of both bacteria and host, and has been used to clarify the mechanisms underlying disease development, and identify metabolic changes, leadings to improved methods for diagnosis, treatment, and prognostication...
April 18, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29678634/the-prognostic-value-of-hoxa13-in-solid-tumors-a-meta-analysis
#7
REVIEW
Yaoan Wen, Fangpeng Shu, Yeda Chen, Yiwen Chen, Yu Lan, Xiaolu Duan, Shan-Chao Zhao, Guohua Zeng
PURPOSE: The prognostic value of homeobox (HOX) A13 (HOXA13) in cancer remains uncertain due to limitations of sample size and discrete outcome in previous studies. We performed this meta-analysis to explore the prognostic effect of HOXA13 in patients with solid tumors. METHODS: PubMed, Embase, and Web of Science were searched to identify eligible studies. Hazard ratios (HR) with 95% confidence interval (95%CI) and clinicopathological factors were extracted. Subgroup analysis according to cancer type, sample size and analysis method were also performed...
April 17, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29678633/preanalytical-phase-effects-of-water-ingestion-during-fasting-on-routine-hematological-parameters-in-a-small-cohort-of-young-women
#8
G Unger, S F Benozzi, A Campion, G L Pennacchiotti
BACKGROUND: We analyze the effects of water ingestion before blood extraction on routine hematological parameters. METHODS: Twenty female volunteers -mean 24 y- were included. Blood was collected after a 12 h fast period (T0 ) and 1 h after the ingestion of 300 ml water (T1 ). These parameters were analyzed: white blood cell (WBC) count; WBC differential count including lymphocytes (lym), monocytes (mono), neutrophils, eosinophils (eos), and basophils; red blood cell (RBC) count; hematocrit (hct); hemoglobin (hgb); mean cell volume; mean cell hemoglobin; RBC distribution width; and platelet count (plt)...
April 17, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29678631/platelet-to-lymphocyte-ratio-in-advanced-cancer-review-and-meta-analysis
#9
REVIEW
Bo Li, Pingting Zhou, Yujie Liu, Haifeng Wei, Xinghai Yang, Tianrui Chen, Jianru Xiao
BACKGROUND: Inflammation biomarkers have been introduced into clinical practice for risk-rating in treatment of patients with cancer. We aimed to confirm the prognostic role of platelet-to-lymphocyte ratio (PLR) as a powerful biomarker for patients with advanced cancer. METHOD: A systematic literature search was conducted through PubMed, Embase and Web of Science databases for studies on advanced tumors. Research articles that analyzed the PLR and hazard ratios (HR) in patients with overall survival (OS) or progression-free survival (PFS) data were involved...
April 17, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29673583/novel-artificial-stool-material-for-external-quality-assurance-eqa-on-a-fecal-immunochemical-test-for-hemoglobin-fit-the-confirmed-utility-of-stable-hemoglobin-and-an-internal-standard-material
#10
Ryota Yasui, Miyu Yamada, Shizuka Takehara, Ikunosuke Sakurabayashi, Katsunori Watanabe
The fecal immunochemical test for hemoglobin (FIT), which detects lower gastrointestinal bleeding, is widely accepted for population-based colorectal cancer (CRC) screening programs. However, the FIT screening process has not been standardized yet, and standardizing the pre-analytical phase and establishing an external quality assurance (EQA) program compliant with ISO requirements is urgently needed. Although there have been various attempts to establish EQA materials suitable for FIT, no materials have yet been reported to have sufficient uniformity and acceptable immunochemical stability of hemoglobin (Hb)...
April 16, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29673582/in-silico-prediction-of-the-pathogenic-effect-of-a-novel-variant-of-bckdha-leading-to-classical-maple-syrup-urine-disease-identified-using-clinical-exome-sequencing
#11
Cynthia Fernández-Lainez, Carmen Aláez-Verson, Isabel Ibarra-González, Sergio Enríquez-Flores, Karol Carrillo-Sanchez, Leonardo Flores-Lagunes, Sara Guillén-López, Leticia Belmont-Martínez, Marcela Vela-Amieva
Maple syrup urine disease (MSUD) is a metabolic disorder caused by mutations in three of the branched-chain α-keto acid dehydrogenase complex (BCKDC) genes. Classical MSUD symptom can be observed immediately after birth and include ketoacidosis, irritability, lethargy, and coma, which can lead to death or irreversible neurodevelopmental delay in survivors. The molecular diagnosis of MSUD can be time-consuming and difficult to establish using conventional Sanger sequencing because it could be due to pathogenic variants of any of the BCKDC genes...
April 16, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29655637/analysis-of-human-blood-plasma-cell-free-dna-fragment-size-distribution-using-evagreen-chemistry-based-droplet-digital-pcr-assays
#12
M Rohan Fernando, Chao Jiang, Gary D Krzyzanowski, Wayne L Ryan
BACKGROUND: Plasma cell-free DNA (cfDNA) fragment size distribution provides important information required for diagnostic assay development. We have developed and optimized droplet digital PCR (ddPCR) assays that quantify short and long DNA fragments. These assays were used to analyze plasma cfDNA fragment size distribution in human blood. METHODS: Assays were designed to amplify 76,135, 490 and 905 base pair fragments of human β-actin gene. These assays were used for fragment size analysis of plasma cell-free, exosome and apoptotic body DNA obtained from normal and pregnant donors...
April 12, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29655636/reticulocyte-hemoglobin-content-in-a-large-sample-of-the-general-dutch-population-and-its-relation-to-conventional-iron-status-parameters
#13
A Mireille Baart, Michiel G J Balvers, Maria T E Hopman, Thijs M H Eijsvogels, Jacqueline M T Klein Gunnewiek, Corine A van Kampen
BACKGROUND: No full consensus exists on which iron status parameters to use for iron status assessment. In this study, we assessed the usefulness of measurement of the hemoglobin content of reticulocytes (CHr) in the general population. METHODS: The following iron status parameters were assessed in 1024 adults: CHr, reticulocytes, hemoglobin (Hb), ferritin, serum iron, transferrin, transferrin saturation and mean corpuscular volume (MCV). Mean parameter values and correlation coefficients for CHr and other parameters were calculated...
April 12, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29654787/prognostic-role-of-microrna-155-in-patients-with-leukemia-a-meta-analysis
#14
REVIEW
Xiaoyu Zhang, Yong Wang, Qiang Guo, Yutao Diao, Hongyan Liu, Guanhua Song, Wei Wang, Zhiyong Zhang, Haipeng Yin, Lianlian Li
BACKGROUND: Recent studies have shown that microRNA-155 (miR-155) is correlated with clinical outcomes of leukemia. This meta-analysis explores to evaluate the prognostic value of miR-155 for survival in patients with leukemia. METHODS: Eligible studies were searched from PubMed and EMBASE databases. Hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) for overall survival (OS), disease-free survival, event-free survival, progression-free survival and treatment-free survival were extracted, if available...
April 11, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29654786/biochemical-and-molecular-analyses-of-infantile-sialic-acid-storage-disease-in-a-patient-with-nonimmune-hydrops-fetalis
#15
Eungu Kang, Yoon-Myung Kim, Sun Hee Heo, Euiseok Jung, Ki-Soo Kim, Hyun Ju Yoo, Eun Na Kim, Chong Jai Kim, Gu-Hwan Kim, Beom Hee Lee
Nonimmune hydrops fetalis is the most severe clinical manifestation of lysosomal storage diseases (LSDs). Around 14 different LSDs have been accounted for as 1-15% of the cause of nonimmune hydrops fetalis. We report a Korean infant affected by an extremely rare but severe form of sialic acid storage disease. The patient presented with nonimmune hydrops fetalis, dysmorphic facial features, hepatosplenomegaly, and dysostosis multiplex and died at 39 days of age due to persistent pulmonary hypertension. LSD was suspected based on the presence of diffuse vacuolation of syncytiotrophoblast, villous stromal cells, and intermediate trophoblast in placental biopsy...
April 11, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29654785/a-metabolomics-study-on-the-immunosuppressive-effect-of-tripterygium-hypoglaucum-levl-hutch-in-mice-the-discovery-of-pathway-differences-in-serum-metabolites
#16
Yanlei Guo, Yongde Wang, Xuan Shi, Weihan Qin, Xiaomei Zhang, Jiahong Xu, Xiaoling Liu, Dajian Yang, Yong Yang
Tripterygium hypoglaucum (Levl.) Hutch (THH), a typical traditional Chinese medicine, is widely used in clinical practice for the treatment of rheumatoid arthritis, systemic lupus erythematous, and other connective tissue and autoimmune diseases. However, most related researches focused on the pharmacological effects of THH, while less attention has been paid to the immunosuppressive mechanism. The present study aims to determine the metabolic profiles, based on UPLC-Q-TOF-MS, identify differential metabolites, and find related metabolic pathways among the sensitization red blood cell (SRBC) model mice, THH treated mice, and cyclophosphamide treated group...
April 11, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29653085/prognostic-significance-of-pre-resection-albumin-fibrinogen-ratio-in-patients-with-non-small-cell-lung-cancer-a-propensity-score-matching-analysis
#17
Shuaishuai Chen, Haixi Yan, Juping Du, Jun Li, Bo Shen, Haijian Ying, Ying Zhang, Shiyong Chen
BACKGROUND: Nutrition and coagulation play important roles in cancer progression. This study was aimed to investigate the value of the albumin/fibrinogen ratio (AFR) in non-small cell lung cancer (NSCLC) patients, through a propensity score matching (PSM) method. METHODS: We retrospectively analyzed 529 NSCLC patients underwent surgical resection from 2010 to 2015. PSM was used to eliminate possible biases. A Cox proportional hazards regression model was performed to evaluate the prognostic value of AFR in NSCLC...
April 10, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29653084/calcium-dobesilate-a-drug-treatment-for-diabetic-retinopathy-can-negatively-interfere-with-the-measurement-of-glycated-albumin-using-the-enzymatic-method
#18
Xiuzhi Guo, Fang Zhao, Yicong Yin, Danchen Wang, Li'an Hou, Jie Wu, Dandan Li, Xinqi Cheng, Liangyu Xia, Ermu Xu, Ling Qiu
BACKGROUND: We reported that calcium dobesilate, a vasoprotective agent mainly used for diabetic retinopathy (DR), negatively interferes with glycated albumin (GA) assays involving enzymatic methods. METHODS: A calcium dobesilate standard was added to 3serum pools in vitro to prepare concentration-response series according to Clinical and Laboratory Standards Institute EP7-A2 guidelines. Percentage deviation between each drug concentration and the drug-free sample was calculated for 6 commercially available GA assays...
April 10, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29649453/potential-role-of-omics-technique-in-prenatal-diagnosis-of-congenital-heart-defects
#19
REVIEW
Lizhu Chen, Johnny Guan, Qiuju Wei, Zhengwei Yuan, Mo Zhang
Congenital heart defect (CHD) is one of the most common birth defects and is the leading cause of neonatal death. Currently, there are no biomarkers available for prenatal diagnosis of CHD. Clinical strategies to diagnose CHD mostly depend on fetal echocardiography. Recent advances in "omics" techniques have opened up new possibilities for biomarker discoveries. In this review, we discuss recent advances in prenatal detection of CHD using biomarkers obtained by "omics" approaches, including genomics, proteomics, metabolomics, and others...
April 10, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29649456/prognostic-value-of-pretreatment-plasma-d-dimer-levels-in-patients-with-diffuse-large-b-cell-lymphoma-dlbcl
#20
Bin Liu, Bo Li, Pingting Zhou, Wenqin Yue, Tao Wang, Jianmin Wang, Xiaoxia Hu, Weiping Zhang, Jie Chen, Li Chen, Lei Gao, Miaoxia He, Jianmin Yang
BACKGROUND: We assessed the prognostic significance of D-dimer in patients of diffuse large B cell lymphoma (DLBCL). METHODS: We performed a retrospective study including 254 patients who were newly diagnosed DLBCL. X-tile was used to generate a cutoff value for D-dimer. Both univariate screen by Cox proportional hazard model and multivariable analysis by Cox regression model were used to assess the impact of pretreatment D-dimer levels on the overall survival (OS)...
April 9, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
journal
journal
25415
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"