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https://www.readbyqxmd.com/read/30636518/total-joint-replacement-in-sub-saharan-africa-a-systematic-review
#1
Peter Se Davies, Simon M Graham, Sithombo Maqungo, William J Harrison
Outcomes of arthroplasty in sub-Saharan Africa are not widely reported. To our knowledge, this systematic review is the first to explore this topic. Scopus, EMBASE, Medline and PubMed databases were searched, utilising MeSH headings and Boolean search strategies. All papers from South Africa were excluded. Twelve papers reporting 606 total hip replacements (THRs) and 763 total knee replacements (TKRs) were included. Avascular necrosis was the most common indication for THR, whereas osteoarthritis was the main indication for TKR...
January 12, 2019: Tropical Doctor
https://www.readbyqxmd.com/read/30636517/clinico-epidemiological-profile-and-predictors-of-outcome-in-children-with-diphtheria-a-study-from-northern-india
#2
Nabaneeta Dash, Sanjay Verma, Muralidharan Jayashree, Rakesh Kumar, Pankaj C Vaidya, Meenu Singh
Diphtheria, a vaccine preventable disease in children, is still being reported from India. Details of 99 children with a clinical diagnosis of diphtheria admitted to a paediatric tertiary care teaching and referral hospital between January 2008 and December 2015 were collected retrospectively and analysed. The median (interquartile range [IQR]) age of the study group was 7.0 years (IQR = 5.0-8.0 years). Nearly two-thirds were unimmunised. Clinical features included fever (97%), dysphagia (82%), sore throat (67%), bull neck (54%), stridor (40%), neuropathy (27%) and nasal discharge (14%)...
January 12, 2019: Tropical Doctor
https://www.readbyqxmd.com/read/30614411/diagnostic-utility-of-bone-marrow-examination-in-evaluation-of-fever-a-descriptive-study-on-98-immunocompetent-adults-from-a-tertiary-care-institute-in-south-india
#3
Sri Krishna Sai, Somanath Padhi, Renu G Boy Varghese, Reba Kanungo, Aneesh Basheer, Nayyar Iqbal
Five-year clinico-laboratory data from 99 (one HIV seropositive) adults (mean age = 41.3 ± 20.4 years) who underwent bone marrow examination for fever persisting for ≥ 1 week were analysed and correlated with microbiological characteristics. Infections, reactive marrow changes and haematolymphoid malignancies were most commonly associated with fever. A high concordance rate of 71% was noted between aspiration and trephine biopsies. Bone marrow granulomas (BMG) were seen exclusively on sections and were most commonly of tubercular and typhoidal in origin (two Salmonella Typhi, one Salmonella Paratyphi A)...
January 6, 2019: Tropical Doctor
https://www.readbyqxmd.com/read/30602348/ambiguous-skin-ulcer-on-the-ear-pinna
#4
Nazar Abdalla
Cutaneous leishmaniasis (CL) is a parasitic disease which has a biphasic life cycle; infection by promastigotes from the sandfly reaches a wound where it is phagocytosed by macrophages, producing the amastigote (the Leishmania donovani body) in the host. A protozoan parasite transmitted by the phlebotomous sandfly causes human leishmaniasis. Cutaneous forms include classical cutaneous, mucocutaneous and post-kala-azar dermal leishmaniasis. It affects c. 300 million individuals in more than 90 nations around the globe...
January 2, 2019: Tropical Doctor
https://www.readbyqxmd.com/read/30602347/brain-death-in-low-income-countries-a-report-from-malawi
#5
Meghan Prin, Caroline Quinsey, Clement Kadyaudzu, Eldad Hadar, Anthony Charles
Most low-income nations have no practice guidelines for brain death; data describing brain death in these regions is absent. Our retrospective study describes the prevalence of brain death among patients treated in an intensive care unit (ICU) at a referral hospital in Malawi. The primary outcome was designation of brain death in the medical chart. Of 449 ICU patients included for analysis between September 2016 and May 2018, 43 (9.6%) were diagnosed with brain death during the ICU admission. The most common diagnostic reasons for admission among these patients were trauma (49%), malaria (16%) and postoperative monitoring after general abdominal surgery (19%)...
January 2, 2019: Tropical Doctor
https://www.readbyqxmd.com/read/30591000/a-challenging-case-of-pyrexia-of-unknown-origin-adrenal-histoplasmosis-mimicking-tuberculosis-in-a-patient-with-chronic-hepatitis-c
#6
Venkat Ramesh, Suneetha Narreddy, Swarnalata Gowrishankar, Ravikiran Barigala, Sagarika Nanda
We present an unusual case of fever of unknown origin with bilateral adrenal masses in a patient with compensated chronic liver disease (compensated) due to hepatitis C who had been treated elsewhere with four months of anti-tuberculous therapy for suspected disseminated tuberculosis (TB). At our institution, he underwent a CT-guided biopsy of the adrenal lesion which to our surprise did not reveal any evidence of TB but a close mimic.
December 28, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30582730/co-existence-of-mycobacterial-infections-is-it-an-emerging-issue-with-retroviral-infections
#7
Bsdp Keragala, Hmmtb Herath, Ghdc Janappriya, C N Gunasekera
We report a 46-year-old woman presenting with leprosy, HIV and active pulmonary tuberculosis (TB). It is advisable to screen for each one of TB, HIV and leprosy patients, especially when an extra feature emerges. Particularly in a leprosy case, if TB remains undiagnosed, the development of rifampicin resistance secondary to monotherapy in leprosy is a major concern.
December 24, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30558480/genitourinary-melioidosis-a-descriptive-study
#8
Maria Koshy, Prashansa Sadanshiv, Sowmya Sathyendra
Melioidosis is the disease caused by the soil and water bacterium, Burkholderia pseudomallei. Our study aimed to delineate its genitourinary manifestations. Over a 10-year period (2006-2016), 20 adults with culture-confirmed genitourinary melioidosis were identified. The patients were all men with a mean age of 45.3 ± 12.3 years. The common risk factors were diabetes mellitus (65%) and alcoholism (25%); a majority of patients (90%) had chronic melioidosis. Most had disseminated disease (n = 17) and 55% were bacteraemic...
December 17, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30541387/ileocaecal-tuberculosis-an-under-recognised-cause-of-vitamin-b-12-deficiency
#9
Ashok Kumar Pannu, Dinesh Raja Palanisamy
A combination of anaemia and knuckle pigmentation should always raise concern for megaloblastic anaemia. As the terminal ileum is the site of vitamin B12 absorption and also the commonest site of abdominal tuberculosis, a clinical triad of prolonged fever, knuckle pigmentation and right lower quadrant abdominal tenderness should suggest ileocaecal tuberculosis in endemic areas.
December 12, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30537911/mycoplasma-pneumoniae-infection-and-asthma-in-children
#10
Surinder Kumar, Ruma Dev Roy, G R Sethi, Sanjeev R Saigal
A clinical association between exacerbation of asthma symptoms and Mycoplasma pneumoniae ( M. pneumoniae) infection has long been suspected. We studied 80 children aged 5-15 years; 50 with asthma (Group 1) and 30 without an acute exacerbation of asthma (Group 2) for detection of M. pneumoniae by serology and polymerase chain reaction (PCR) on nasopharyngeal aspirates. Our study confirms that lower respiratory tract infections with M. pneumoniae are frequently associated with exacerbations of asthma in children...
December 11, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30526377/urine-pregnancy-test-upt-hcg-negative-molar-pregnancy-a-short-report-from-masanga-sierra-leone
#11
T M Gresnigt, J M Sikkema
In Masanga, Sierra Leone, a multigravid woman presented with a urine pregnancy test negative molar pregnancy. This can be explained by the 'hook-effect'. In resource-poor settings where quantitative serum hCG cannot be determined, it is of paramount importance to remain vigilant of the diagnosis of molar pregnancy. Clinical judgement and sonography remain key in diagnosing molar pregnancy in district hospitals in low- and middle-income countries (LMICs), especially since their occurrence is much more common in these countries...
December 7, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30486743/cardiovascular-manifestations-and-patient-outcomes-following-snake-envenomation-a-pilot-study
#12
Aditya John Binu, Ajay Kumar Mishra, Karthik Gunasekaran, Ramya Iyadurai
Cardiotoxicity in snake envenomation has not been adequately explored in the literature. This retrospective, observational study analysed clinical profiles and cardiovascular effects (CVE), with associated outcomes, in snake envenomation. Thirty-four patients were recruited between April 2014 and October 2017. Cardiovascular involvement was seen in 24 (70.6%) patients. Electrocardiographic changes included prolonged QTc (62.5%), T-wave inversion (37.5%) and tall T-waves (12.5%). Hospital stay was 7.2 (SD = 5...
November 28, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30482107/simultaneous-use-of-two-rapid-diagnostic-tests-for-the-diagnosis-of-chagas-disease
#13
Diego Mendicino, Carlina Colussi, Edgardo Moretti
The sensitivity of rapid diagnostic tests (RDT) for Chagas disease is not great enough for their single use. The aim of this paper was to evaluate the performance of two RDTs for Chagas disease, used simultaneously. Two different RDTs (A and B) were performed in 64 and 42 serum samples that were negative and positive, respectively, by conventional serological techniques. Validity and reliability of both tests were evaluated individually and simultaneously. Sensitivity was 90.5% and 97.6%, and specificity was 100% and 93...
November 27, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30458680/newborn-pulse-oximetry-screening-it-s-time-to-have-recommendation-and-universal-implementation-in-india
#14
Shahid Akhtar Siddiqui
No abstract text is available yet for this article.
November 20, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30453836/paediatric-visceral-leishmaniasis-a-retrospective-study-on-clinical-manifestations-demographic-features-and-laboratory-findings-of-hospitalised-cases-in-iran-between-2006-and-2016
#15
Manijeh Nourian, Aliehsan Heidari, Saleheh Tajali, Erfan Ghasemi, Mehdi Mohebali, Amir Heidari
Visceral leishmaniasis (VL) is a neglected disease. Our retrospective study describes 38 clinical and epidemiological characteristics of VL in patients admitted to a paediatric hospital in Tehran, Iran, who came from different geographical regions, indicating that the disease has spread to most parts of the country. Some 76.3% of the children documented suffered with symptoms of the disease for two months before admission.
November 19, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30451091/characteristics-and-outcomes-of-traumatic-spinal-cord-injury-in-a-low-resource-setting
#16
Jessica Eaton, Cornelius Mukuzunga, Joanna Grudziak, Anthony Charles
Spinal cord injury (SCI) is relatively rare and affects an estimated 15-40 per 1 million people globally. All patients admitted from October 2016 to June 2017 at Kamuzu Central Hospital, Malawi with a spinal column injury were retrospectively studied. Out of 1442 patients, 46 had vertebral column injury, and half of these had neurological deficit. The most common mechanism of injury was road traffic crash (45.7%), and cervical SCIs were the most common (41.3%). The overall mortality was 15.2%, thus demonstrating devastating morbidity and mortality...
November 18, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30419777/the-burden-of-chronic-elbow-dislocations-in-cambodia-and-early-results-of-a-cost-effective-surgical-approach
#17
Alice E Mortimer, Alex Nicholls, Aziz Rawal, Saqib Noor, Heang Oy, James G Gollogly
Chronic elbow dislocation presents a surgical challenge and there is difficulty in balancing stability with early mobilisation. We present a series of 103 patients treated with open reduction via a posterior approach and provide early results of an alternative combined medial and lateral approach (Soddo technique, Anderson et al.). Of the 103 patients, 81% initially consulted a traditional healer and the mean dislocation period was 11 weeks. There was significant loss to follow-up. Only 12 patients having undergone the posterior approach had complete datasets...
November 12, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30419776/unmet-need-for-contraception-among-hiv-positive-women-in-ile-ife-nigeria
#18
Temitope Omoladun Okunola, Kayode T Ijaduola, Ebunoluwa A Adejuyigbe
As mother-to-child transmission of HIV is difficult to predict and also hard to prevent in practice, pregnancy among women living with HIV/AIDS (WHA) needs to be taken with considerable aforethought. The prevention of unwanted pregnancy among WHA is therefore a public health issue. The aim of our study was to determine the unmet need for contraception among HIV-positive women and the associated factors. Ours was a cross-sectional study involving 425 non-pregnant WHA attending an adult HIV clinic in Nigeria...
November 12, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30419775/ophthalmomyiasis-externa-due-to-sheep-nasal-botfly-in-rural-jamaica
#19
Valence Jordan, Lizette Mowatt
We present the case of a young male patient who presented with pain, redness and foreign body sensation in his left eye. There was no associated decrease in vision. Three live larvae were removed from his left conjunctival sac and sent to the laboratory for identification. The patient was treated symptomatically and his symptoms were mostly resolved by the following day. The larvae were later identified as the first instar of the sheep nasal botfly. Poor sanitation and exposure to livestock were among the identified risk factors in this case...
November 12, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/30394857/scrotal-abscess-consequent-on-syphilitic-epididymo-orchitis
#20
Vivek Agrawal, Rohit Ranjan
Syphilis is notorious and a great imitator of all diseases. It is a chronic bacterial infection, caused by the sexually transmitted spirochete, Treponema pallidum. Though it has drastically reduced in prevalence, its recent resurgence (especially with HIV disease) is worrying. Without treatment, the disease can progress over years through a series of clinical stages and lead to irreversible neurological or cardiovascular complications. The disease may occur in any organ, including the testis, and is commonly mistaken for malignancy...
November 4, 2018: Tropical Doctor
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