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Cardiology

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https://www.readbyqxmd.com/read/28099954/an-evolution-of-management-in-hypertrophic-cardiomyopathy-myectomy-alcohol-septal-ablation-mitral-valve-replacement-mitraclip
#1
Konstantinos Dean Boudoulas, Harisios Boudoulas
No abstract text is available yet for this article.
January 19, 2017: Cardiology
https://www.readbyqxmd.com/read/28095388/the-use-of-mitraclip-for-symptomatic-patients-with-hypertrophic-obstructive-cardiomyopathy
#2
Felix Thomas, Florian Rader, Robert J Siegel
OBJECTIVES: Current nonpharmacological therapies for symptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM), including septal myectomy and alcohol septal ablation (ASA), carry significant risks for serious cardiac conduction abnormalities. We present a review of the currently available published data regarding the novel use of the relatively low-risk MitraClip® system in the treatment of symptomatic patients. METHODS: Data were collected from 4 separate studies on the use of the MitraClip on 15 symptomatic HOCM patients with systolic anterior motion (SAM) of the mitral valve apparatus...
January 18, 2017: Cardiology
https://www.readbyqxmd.com/read/28068653/exosomes-derived-from-human-pulmonary-artery-endothelial-cells-shift-the-balance-between-proliferation-and-apoptosis-of-smooth-muscle-cells
#3
Lin Zhao, Hui Luo, Xiaohui Li, Tangzhiming Li, Jingni He, Qiangqiang Qi, Yuwei Liu, Zaixin Yu
BACKGROUND: The overproliferation of pulmonary vascular cells is noted in pulmonary hypertension. The role of exosomes from pulmonary artery endothelial cells (PAEC) in the proliferation and apoptosis of pulmonary artery smooth muscle cells (PASMC) remains unclear. METHODS: Exosomes were isolated and purified from the culture medium of PAEC using a commercial kit. Lipopolysaccharide (LPS), hypoxia, and hydrogen peroxide were utilized to induce PAEC injury. Coculture of PAEC and PASMC was conducted using Transwell plates, and GW4869 was applied to inhibit exosome release...
January 10, 2017: Cardiology
https://www.readbyqxmd.com/read/27988518/conduction-abnormalities-after-transcatheter-aortic-valve-implantation-and-diastolic-dysfunction
#4
Ofir Priesler, Simon Biner, Ariel Finkelstein, Yoav Michowitz
OBJECTIVES: Transcatheter aortic valve implantation (TAVI) is frequently associated with the development of conduction abnormalities. We assessed the effect of conduction abnormalities on diastolic function following TAVI. METHODS: In total, 101 consecutive post-TAVI patients were included, each with echocardiographic follow-up at 1 and 6 months. Diastolic properties were correlated with the occurrence of a long PR interval and wide QRS, and their change from baseline...
December 17, 2016: Cardiology
https://www.readbyqxmd.com/read/27988513/relationship-between-serum-inflammatory-biomarkers-and-thrombus-characteristics-in-patients-with-st-segment-elevation-myocardial-infarction
#5
Giampaolo Niccoli, Alberto Menozzi, Davide Capodanno, Carlo Trani, Vasile Sirbu, Massimo Fineschi, Chiara Zara, Filippo Crea, Daniela Trabattoni, Francesco Saia, Elena Ladich, Giuseppe Biondi Zoccai, Guilherme Attizzani, Giulio Guagliumi
OBJECTIVES: To compare angiographic and optical coherence tomography (OCT) data pertinent to thrombi, along with the histologic characteristics of aspirated thrombi in patients presenting with ST elevation myocardial infarction (STEMI) with or without inflammation, as assessed by C-reactive protein (CRP) and myeloperoxidase (MPO). METHODS: In the OCTAVIA (Optical Coherence Tomography Assessment of Gender Diversity in Primary Angioplasty) study, 140 patients with STEMI referred for primary percutaneous intervention were enrolled...
December 17, 2016: Cardiology
https://www.readbyqxmd.com/read/27978528/drug-eluting-balloon-technology-for-native-non-small-coronary-artery-disease-another-crusade-against-skepticism
#6
Dario Buccheri
No abstract text is available yet for this article.
December 16, 2016: Cardiology
https://www.readbyqxmd.com/read/27978523/paravalvular-regurgitation-after-transcutaneous-aortic-valve-replacement-a-dynamic-lesion
#7
Gregg S Pressman
No abstract text is available yet for this article.
December 16, 2016: Cardiology
https://www.readbyqxmd.com/read/27974724/myocardial-infarction-after-ozone-therapy-is-ozone-therapy-dr-jekyll-or-mr-hyde
#8
Çağın Mustafa Üreyen, Cem Yunus Baş, Şakir Arslan
No abstract text is available yet for this article.
December 15, 2016: Cardiology
https://www.readbyqxmd.com/read/27960178/use-and-disuse-of-observational-research-the-case-of-remote-monitoring-in-heart-failure
#9
Luigi Tavazzi, Jeffrey S Borer, Guido Tavazzi
No abstract text is available yet for this article.
December 14, 2016: Cardiology
https://www.readbyqxmd.com/read/27951539/wellens-syndrome-with-syncope-but-not-chest-pain
#10
Omar Z Yasin, Alberto Rubio-Tapia, Maurice E Sarano
We report the case of a woman in her 70s presenting to the emergency department with syncope, troponemia, and an electrocardiogram with deep symmetric T-wave inversions in V2 and V3 and prolonged QTc. Her presentation was concerning for acute coronary syndrome, Wellens syndrome in particular, given the elevated troponin levels, lack of ST segment changes, and characteristic T-wave findings. The diagnosis was confirmed with angiography that showed a critical left anterior descending (LAD) artery occlusion. Since myocardial infarction does not typically present with syncope, we explored the differential diagnoses for T-wave inversions, which include electrolyte abnormalities, medications, intracranial hemorrhage, pulmonary embolism, and other cardiac diseases that were ruled out in our patient...
December 13, 2016: Cardiology
https://www.readbyqxmd.com/read/27925612/transthoracic-echocardiography-to-assess-aortic-regurgitation-after-tavr-a-comparison-with-periprocedural-transesophageal-echocardiography
#11
Alexandra Goncalves, Charles Nyman, David R Okada, Avinainder Singh, Jeffrey Swanson, Michael Cheezum, Michael Steigner, Marcelo Di Carli, Scott Solomon, Pinak B Shah, Deepak L Bhatt, Douglas Shook, Ron Blankstein
BACKGROUND: We aimed to compare periprocedural transesophageal echocardiography (TEE) with postprocedural transthoracic echocardiography (TTE) for the diagnosis of aortic regurgitation (AR). METHODS AND RESULTS: TEE and TTE images of 163 transcatheter aortic valve replacement (TAVR) patients (mean age 81 ± 8 years; 56% men) were reviewed separately and blinded to each other as well as to all clinical data. The median time between TEE during TAVR (TEE/TAVR) and TTE was 4 days (IQR 2-10 days)...
December 8, 2016: Cardiology
https://www.readbyqxmd.com/read/27923231/congenital-absence-of-the-pericardium-a-systematic-approach-to-diagnosis-and-management
#12
Bo Xu, Jorge Betancor, Craig Asher, Adriana Rosario, Allan Klein
Congenital absence of the pericardium (CAP) is a rare condition. Failure to recognize the clinical features of this condition can lead to incorrect and delayed diagnosis. Limited data are available regarding the optimal approach to diagnose and manage patients with suspected CAP. Due to the rare nature of CAP, this condition can present diagnostic and management dilemmas for clinicians. Using 3 cases of CAP as a framework, a clinically focused review on the diagnosis and management of CAP is presented. Clinicians will be provided with a systematic approach to evaluating patients with suspected CAP, incorporating key history, examination, and multimodality cardiovascular imaging investigations...
December 7, 2016: Cardiology
https://www.readbyqxmd.com/read/27894109/ozone-therapy-and-its-use-in-medicine-further-comments
#13
Lamberto Re, Robert Rowen, Valter Travagli
No abstract text is available yet for this article.
November 29, 2016: Cardiology
https://www.readbyqxmd.com/read/27880950/protease-activated-receptor-1-contributes-to-angiotensin-ii-induced-cardiovascular-remodeling-and-inflammation
#14
Silvio Antoniak, Jessica C Cardenas, Laura J Buczek, Frank C Church, Nigel Mackman, Rafal Pawlinski
BACKGROUND: Angiotensin II (Ang II) plays an important role in cardiovascular disease. It also leads to the activation of coagulation. The coagulation protease thrombin induces cellular responses by activating protease-activated receptor 1 (PAR-1). We investigated whether PAR-1 contributes to Ang II-induced cardiovascular remodeling and inflammation. METHODS AND RESULTS: PAR-1+/+ (wild-type; WT) and PAR-1-/- mice were infused with Ang II (600 ng/kg/min) for up to 4 weeks...
November 24, 2016: Cardiology
https://www.readbyqxmd.com/read/27846629/assessment-of-a-drug-eluting-balloon-for-the-treatment-of-de-novo-coronary-lesions-guided-by-optical-coherence-tomography-study-protocol-for-a-randomized-controlled-trial
#15
Bo Li, Yu Ding, Feng Tian, Weiren Chen, Tianwen Han, Yundai Chen
BACKGROUND: The drug-eluting balloon (DEB) is a promising tool to prevent restenosis after coronary angioplasty. However, data on the outcomes of DEB in de novo lesions are scarce. Vessel recoil and constrictive remodeling are the dominant causes of restenosis after angioplasty. The use of cutting balloons (CB) may effectively reduce elastic recoil after balloon dilation. In this study, we evaluate the efficacy and safety of DEB in treating de novo coronary artery lesions, using a predilation strategy with cutting balloon (CB) dilation before DEB angioplasty...
November 16, 2016: Cardiology
https://www.readbyqxmd.com/read/27832643/cardiac-surgery-for-carcinoid-heart-disease-a-weapon-not-to-be-misused
#16
Maria Bonou, Chris J Kapelios, Gregory Kaltsas, Konstantinos Perreas, Konstantinos Toutouzas, John Barbetseas
Carcinoid heart disease (CHD) complicates approximately 25% of patients with a carcinoid tumor and carcinoid syndrome and leads to heart valve degeneration with mixed-stenotic and regurgitation pathology and consequent heart failure (HF) leading to significant morbidity and mortality. Cardiac surgery in symptomatic, severe CHD leads to significantly better functional capacity and prolonged survival when compared to medical treatment alone. Recent studies have shown improvement in postoperative outcomes of patients undergoing surgery for CHD over the last decades...
November 11, 2016: Cardiology
https://www.readbyqxmd.com/read/27829244/red-cell-distribution-width-and-hemorrhagic-events-related-to-dabigatran-use
#17
Ibrahim Halil Altiparmak, Feyzullah Besli
No abstract text is available yet for this article.
November 10, 2016: Cardiology
https://www.readbyqxmd.com/read/27825159/injection-of-htert-transduced-endothelial-progenitor-cells-promotes-beneficial-aortic-changes-in-a-high-fat-dietary-model-of-early-atherosclerosis
#18
Xingsheng Li, Yanru Deng, Shunrong Zhao, Dandan Zhang, Qingwei Chen
OBJECTIVES: Cultured endothelial progenitor cells (EPCs) display troubling issues that adversely affect their applicability to endothelial regeneration. We hypothesized that transduction of the human telomerase catalytic subunit (hTERT) gene would enhance EPC function in treating dietary-induced early atherosclerosis (AS). METHODS: A dietary-induced early AS model was successfully constructed in 90 healthy male rats, while 30 healthy control (HC) rats were normally fed...
November 9, 2016: Cardiology
https://www.readbyqxmd.com/read/27825157/biomarkers-in-heart-failure-with-preserved-ejection-fraction-problems-and-opportunities
#19
Filippos K Triposkiadis
No abstract text is available yet for this article.
November 9, 2016: Cardiology
https://www.readbyqxmd.com/read/27816974/troponin-i-and-d-dimer-for-discriminating-acute-pulmonary-thromboembolism-from-myocardial-infarction
#20
Soo Jin Kim, Moo Hyun Kim, Kwang Min Lee, Tae Hyung Kim, Sun Yong Choi, Min Kook Son, Ji Woen Park, Victor L Serebruany
BACKGROUND: Acute pulmonary thromboembolism (APTE) is a life-threatening condition, often manifesting with chest pain, dyspnea, and increased cardiac biomarkers including cardiac troponin I (CTI) and D-dimer. Therefore, APTE is often misdiagnosed with classical non-ST elevation myocardial infarction (NSTEMI), resulting in unnecessary coronary interventions and a delay of therapy. OBJECTIVES: Our aim was to distinguish APTE from NSTEMI based on CTI and D-dimer levels...
November 5, 2016: Cardiology
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