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Cardiology

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https://www.readbyqxmd.com/read/30317228/the-accuracy-of-a-large-v-wave-in-the-pulmonary-capillary-wedge-pressure-waveform-for-diagnosing-current-mitral-regurgitation
#1
Hideyuki Hayashi, Yukio Abe, Yusuke Morita, Eisaku Nakane, Yoshizumi Haruna, Tetsuya Haruna, Moriaki Inoko
BACKGROUND: Large V waves in the pulmonary capillary wedge pressure (PCWP) waveform traditionally indicate severe mitral regurgitation (MR). However, our understanding of MR etiology and hemodynamics has changed in recent decades. OBJECTIVES: We aimed to reevaluate the association between large V waves and current MR to determine whether traditional large V wave criteria remain optimal. METHOD: We reviewed 1,964 right heart catheterizations (RHCs) performed at our institution from 2010 to 2017, and retrospectively selected 126 patients with sinus rhythm who underwent echocardiography within 2 days (0...
October 12, 2018: Cardiology
https://www.readbyqxmd.com/read/30304721/matrix-gla-protein-plaque-stability-and-cardiovascular-events-in-patients-with-severe-atherosclerotic-disease
#2
Sabine R Zwakenberg, Yvonne T van der Schouw, Cees Vermeer, Gerard Pasterkamp, Hester M den Ruijter, Joline W J Beulens
OBJECTIVE: This study aims to investigate whether plasma matrix Gla protein (MGP) species, desphospho-uncarboxylated (dp-uc) MGP, and total uncarboxylated (t-uc) MGP are associated with plaque levels of uncarboxylated (uc) MGP, markers of plaque stability, and cardiovascular disease (CVD) risk. METHODS: From the Athero-Express biobank, we selected carotid plaque samples of 100 patients who underwent carotid endarterectomy. The level of agreement between plasma MGP species and plaque ucMGP levels was assessed using weighted kappa (κ)...
October 10, 2018: Cardiology
https://www.readbyqxmd.com/read/30304720/the-utility-of-flow-rate-compared-with-left-ventricular-stroke-volume-index-in-the-hemodynamic-classification-of-severe-aortic-stenosis-with-preserved-ejection-fraction
#3
Dragos Alexandru, Simcha Pollack, Florentina Petillo, J Jane Cao, Eddy Barasch
OBJECTIVES: To substitute the stroke volume index (SVi) with flow rate (FR) in the hemodynamic classification of severe aortic stenosis (AS) with preserved ejection fraction (EF), in order to evaluate its prognostic value. METHODS: A total of 529 patients (78.8 ± 9.8 years old, 44.1% males) with isolated severe AS (aortic valve area, AVA < 1 cm2), EF ≥50%, in sinus rhythm, who underwent transthoracic echocardiography, were stratified by FR (≥/< 200 mL/s) and mean pressure gradient (MG) (≥/< 40 mm Hg): FRnormal/MGhigh, FRlow/MGhigh, FRnormal/MGlow, and FRlow/MGlow...
October 10, 2018: Cardiology
https://www.readbyqxmd.com/read/30304719/changes-in-profiles-of-kawasaki-disease-noted-over-time-in-suzhou-china
#4
Ling Sun, Yunjia Tang, Ye Wang, Guanghui Qian, Wenhua Yan, Bo Wang, Xuan Li, Haitao Lv
OBJECTIVES: The purpose of the present study was to explore the changes in epidemiological, clinical and laboratory characteristics of Kawasaki disease (KD) over a 12-year period in this area. METHODS: The medical records of KD patients hospitalized in the Children's Hospital of Soochow University from January 2006 to December 2017 were retrospectively reviewed and analyzed. To elucidate the changes more clearly in these years, we divided all patients into three groups according to the time of admission, 5-year time intervals apart...
October 10, 2018: Cardiology
https://www.readbyqxmd.com/read/30293082/the-effect-of-autoantibody-against-m2-muscarinic-acetylcholine-receptor-in-heart-failure-patients-on-digoxin-treatment
#5
Dongyan Hou, Zhenping Fan, Lin Xu, Hua Wang, Zhiyong Zhang, Guiling Ma, Xiaorong Xu, Xin Wang, Juan Zhang, Jiamei Liu, Lin Zhang
BACKGROUND: Autoantibody against M2-muscarinic acetylcholine receptor (anti-M2AChR) has a biological effect similar to a vagus agonist. Digoxin has a function of vagus nervous system stimulation. We hypothesized that anti-M2AChR is highly correlated with digoxin in patients with chronic heart failure (CHF). METHODS: Synthetic M2AChR peptides served as the target antigen in an ELISA were used to screen the sera of 80 CHF patients, who were separated into a negative (-) or positive (+) anti-M2AChR group according to their anti-M2AChR reactivity...
October 5, 2018: Cardiology
https://www.readbyqxmd.com/read/30293068/relation-of-the-ankle-brachial-index-to-left-ventricular-ejection-fraction-in-patients-without-coronary-artery-disease
#6
Arismendy Nunez, Sophia Russ, Muhammad Ihsan, Sarah Gaballah, Attiya Haque, Clive Goulbourne, Dale Railwah, Ryan Massay, Muhammad Afzal Khan, Louis Salciccioli, Mark Stewart, Jason M Lazar
BACKGROUND: The low ankle brachial index (ABI) values are indicative of peripheral arterial disease, but have recently been found to be associated with reduced left ventricular ejection fraction (LVEF). This may relate to coexisting coronary artery disease (CAD). AIM: This study prospectively assessed a potential ABI-LVEF association in patients without CAD. METHODS AND RESULTS: We studied 55 patients (age 57 ± 13 years, 49% male) with normal coronary arteries with LVEF determination...
October 5, 2018: Cardiology
https://www.readbyqxmd.com/read/30227400/evaluation-of-left-ventricular-performance-is-there-a-gold-standard
#7
Konstantinos Dean Boudoulas, Filippos Triposkiadis, Harisios Boudoulas
No abstract text is available yet for this article.
September 18, 2018: Cardiology
https://www.readbyqxmd.com/read/30227396/short-term-high-intensity-interval-training-is-superior-to-moderate-intensity-continuous-training-in-improving-cardiac-autonomic-function-in-children
#8
Anneke van Biljon, Andrew J McKune, Katrina D DuBose, Unathi Kolanisi, Stuart J Semple
OBJECTIVES: This study aimed to investigate the impact of 3 isocaloric exercise programs on cardiac autonomic nervous system (ANS) functioning in children. METHODS: One hundred nine children (39% boys and 61% girls) aged 10-13 years (mean 11.07 ± 0.81) were conveniently assigned to 1 of 4 groups as follows: Moderate-intensity continuous training (MICT; n = 29) at 65-70% of the predicted maximum heart rate (MHR), High-intensity interval training (HIIT; n = 29) at > 80% of the predicted MHR, HIIT and MICT combined on alternate weeks (ALT; n = 27), and a control group (n = 24)...
September 18, 2018: Cardiology
https://www.readbyqxmd.com/read/30212826/obstructive-sleep-apnea-and-sudden-cardiac-death-is-the-landscape-clear
#9
Emmanuel N Simantirakis, Panteleimon E Papakonstantinou
No abstract text is available yet for this article.
September 13, 2018: Cardiology
https://www.readbyqxmd.com/read/30205374/clues-to-the-pathophysiology-of-sudden-cardiac-death-in-obstructive-sleep-apnea
#10
REVIEW
Tatyana Olegovna Brodovskaya, Irina Fedorovna Grishina, Tatiana Fedorovna Peretolchina, Olga Georgievna Solenskaia, Olga Petrovna Kovtun, Olga Vyacheslavovna Teplyakova, Sergey Aleksandrovich Chernjadev, Artem Anatolievich Popov, Viacheslav Valentinovich Kurmin
BACKGROUND: Risk assessment of sudden cardiac death (SCD) is multifactorial and complex, especially among individuals without established cardiovascular disease. There are insufficiently investigated conditions that can affect arrhythmogenesis. One such condition is obstructive sleep apnea (OSA) syndrome, which is not on the list of risk factors of the Russian National Society of Arrhythmology. OBJECTIVE: The aim of this review article is to discuss clues to the pathophysiology of SCD in OSA subjects...
September 11, 2018: Cardiology
https://www.readbyqxmd.com/read/30176665/association-between-radiotherapy-and-anatomic-severity-of-coronary-artery-disease-a-propensity-score-matching-comparison-among-adult-onset-thoracic-cancer-survivors
#11
Shunying Hu, Hai Gao, Jianzhong Zhang, Xian Han, Qian Yang, Juan Zhang, Yundai Chen
OBJECTIVE: To investigate the association between radiotherapy and anatomic severity of coronary artery disease (CAD) using the SYNTAX scores (SXscores) of coronary angiograms in adult-onset thoracic cancer survivors. METHODS: A total of 152 patients who previously had thoracic cancer and underwent coronary angiography between 2010 and 2016 were examined. Propensity score matching (PSM) was used to identify 27 well-matched pairs of patients. Characteristics and coronary angiograms were collected from each patient...
September 3, 2018: Cardiology
https://www.readbyqxmd.com/read/30138945/survival-after-aortic-valve-replacement-for-aortic-regurgitation-prediction-from-preoperative-contractility-measurement
#12
Jeffrey S Borer, Phyllis G Supino, Edmund McM Herrold, Antony Innasimuthu, Clare Hochreiter, Karl Krieger, Leonard N Girardi, O Wayne Isom
BACKGROUND: Noninvasive measurement of myocardial contractility (end-systolic wall stress-adjusted change in left ventricular ejection fraction from rest to exercise [ΔLVEF - ΔESS]) predicts heart failure, subnormal LVEFrest, and sudden death in asymptomatic patients with chronic severe aortic regurgitation (AR). Here we assess the relation of preoperative ΔLVEF - ΔESS to survival after aortic valve replacement (AVR). METHODS: Patients who underwent AVR for chronic, isolated, pure severe AR (n = 66) were followed for 13...
August 23, 2018: Cardiology
https://www.readbyqxmd.com/read/30138936/successful-apixaban-treatment-of-tavr-thrombosis-after-warfarin-failure
#13
Saleen Khan, Olisaemeka Achike, Rajasekhar Nekkanti, Blase Carabello
In this study, we present a case of progressive transcatheter aortic valve replacement thrombosis in a patient receiving warfarin that resolved with treatment with heparin and apixaban.
August 23, 2018: Cardiology
https://www.readbyqxmd.com/read/30138928/cyp2c19-genetic-polymorphism-and-pharmacodynamics-of-prasugrel-maintenance-dose-in-patients-undergoing-percutaneous-coronary-intervention
#14
George Kassimis, Dimitrios Alexopoulos
No abstract text is available yet for this article.
August 23, 2018: Cardiology
https://www.readbyqxmd.com/read/30138919/antithrombotic-therapy-after-bioprosthetic-aortic-valve-replacement-a-therapeutic-morass
#15
REVIEW
Anton A Gryaznov, Ayman Saeyeldin, Mohamed Abdelbaky, Mohammad A Zafar, Maryam Tanweer, Mahnoor Imran, Dimitra Papanikolaou, Young Erben, Julia Zefirova, Bulat A Ziganshin, John A Elefteriades
Valvular heart disease is a common pathologic condition that affects 6 million people in the United States and more than 100 million worldwide. The most common valvular disorder is aortic stenosis. Current American and European guidelines recommend surgical management for symptomatic aortic stenosis with low risk of perioperative complications and endovascular intervention for high-risk patients with multiple comorbidities. Considering the increasing volume of aortic valve replacement (AVR) with biological valves, it is very important to select the appropriate anticoagulant after surgical AVR...
August 23, 2018: Cardiology
https://www.readbyqxmd.com/read/30138917/an-hs-tnt-second-peak-associated-with-high-crp-at-day-2-appears-as-potential-biomarkers-of-micro-vascular-occlusion-on-magnetic-resonance-imaging-after-reperfused-st-segment-elevation-myocardial-infarction
#16
Fabien Huet, Mariama Akodad, Nils Kuster, Hélène Kovacsik, Florence Leclercq, Anne-Marie Dupuy, Richard Gervasoni, Gisele Khoury, Jean Christophe Macia, Jean-Paul Cristol, François Roubille
INTRODUCTION: Micro-vascular occlusion (MVO) in a myocardial infarction (MI) is associated with an increased risk of heart failure and mortality. Hs-T-troponin has a double peak kinetic after MI. The aim was to determine if this kinetic was correlated to MVO evaluated by cardiac magnetic resonance imaging (MRI) after MI. METHODS: This is a monocentric retrospective study. Inclusion criteria were hospitalization for MI, Thrombolysis In Myocardial Infarction flow 0 at coronary angiography, reperfusion within 12 h from the onset of chest pain, cardiac MRI within the first month, and a 5-days' biological follow-up with at least hs-T-Troponin and C-reactive protein (CRP)...
August 23, 2018: Cardiology
https://www.readbyqxmd.com/read/30138916/urgent-myocardial-revascularization-in-non-st-segment-elevation-acute-myocardial-infarction-guided-by-speckle-tracking-echocardiography-a-challenging-interventional-decision-making
#17
Fabio Capasso, Marco Pepe, Salvatore Severino, Giuseppe Valva, Pietro Landino, Donato Mele
A 68-year-old man with a non-ST elevation myocardial infarction (NSTEMI) presented with a low risk profile indicating invasive revascularization within 72 h. However, left ventricular (LV) global longitudinal strain (GLS) calculated by two-dimensional speckle tracking echocardiography (2D-STE) in the Emergency Room showed substantial myocardial infarction. Therefore, urgent reperfusion therapy was decided and delivered within 30 min from hospital admission. LV GLS fully recovered after the invasive procedure and the final infarct size was 7%...
August 23, 2018: Cardiology
https://www.readbyqxmd.com/read/30130761/a-6-month-follow-up-study-of-the-relation-between-apolipoprotein-e-gene-polymorphism-and-major-adverse-cardiovascular-events-in-patients-with-acute-coronary-syndrome
#18
Jinggang Xia, Shaodong Hu, Chunlin Yin, Dong Xu
OBJECTIVES: This study aimed to investigate the relation between ApoE gene polymorphisms and major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS) during a 6-month follow-up. METHODS: From October 2016 to July 2017, 211 patients were admitted to a cardiology clinic with a diagnosis of ACS. Blood samples were obtained from all patients on the first day. The primary end point was a 6-month incidence of MACE. ApoE gene polymorphism was genotyped by real-time PCR using TaqMan® SNP Genotyping Assay...
2018: Cardiology
https://www.readbyqxmd.com/read/30130750/the-aortic-stenosis-complex
#19
Konstantinos Dean Boudoulas, Filippos Triposkiadis, Harisios Boudoulas
No abstract text is available yet for this article.
2018: Cardiology
https://www.readbyqxmd.com/read/30099471/care-pathways-in-st-elevation-myocardial-infarction-maybe-a-modern-way-to-hippocrates-oath-harm-less-and-help-more
#20
George Latsios, Kostas Toutouzas, Dimitris Tousoulis
No abstract text is available yet for this article.
2018: Cardiology
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